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Curriculum

Maria TORCIA

Ruolo attuale:: Docente a Contratto

Recapiti

maria.torcia(AT)unifi.it

Maria TORCIA

Curriculum

FIRENZE 14.03.2025

Curriculum vitae
Prof. Maria, Gabriella Torcia,

Professore Associato in Microbiologia e Microbiologia Clinica.(SSD MED/07)

Indirizzo: DIPARTIMENTO DI MEDICINA SPERIMENTALE E CLINICA - VIALE PIERACCINI 6 – 50139 FIRENZE
Telefono +39 3479966990
E-mail maria.torcia@unifi.it
Nazionalità: Italiana
Data di nascita: 24 marzo 1958

Attività didattica
[B030939] - Microbiologia - Corso di Laurea in Medicina E Chirurgia,
[B016765] Microbiologia Generale; Corso di laurea B014 – Biotecnologie
B230: Corso di Laurea - Odontoiatria e Protesi Dentaria (Lm)

Attività Clinica: SoD complessa di Andrologia, Endocrinologia e Incongruenza di
genere-AOU Careggi- Centro di Riferimento Regionale per la Crioconservazione del liquido seminale

Esperienza lavorativa
2010-2025 Professore Associato in Microbiologia e Microbiologia Clinica.(SSD MED/07)
Dipartimento di Medicina Sperimentale e Clinica;
Dirigente Medico SOD Andrologia, Endocrinologia femminile e incongruenza di genere; Azienda Ospedaliero-Universitaria di Careggi, Firenze
2002-2010 Ricercatore a tempo indeterminato: Dipartimento di Medicina Sperimentale e Clinica;
1987-2002: Funzionario Tecnico, Università degli studi di Firenze
1986-1987: Borsa di studio di Associazione Italiana per la Ricerca sul Cancro
1985-1986: Borsa di studio del Ministero Pubblica Istruzione
per attività di ricerca presso Istituto di Clinica Medica IV, Università di Firenze
1981-1984: Specializzazione in Ematologia Generale (Clinica e Laboratorio): Qualifica conseguita con votazione di
70/70 e lode
1981: Laurea in Medicina e Chirurgia con votazione di 110/110 e lode
1975: Maturità scientifica con votazione di 60/60

Esperienze all’estero
1992-1993) Merck Sharp & Dohme Corp Research Laboratories, West Point, PA 19486(Screening di librerie fagiche)
1988-1990 Visiting Researcher at College of Physicians and Surgery, Department of Physiology and Cellular Biophysics, Columbia University, New York, NY

Competenza ed esperienza in vari settori di ricerca e in particolare:
- Immunologia
- Ematologia
- Microbiologia (Interazione Patogeno/Ospite)

Madrelingua: ITALIANO
Altre lingue: INGLESE SPAGNOLO

Coordinatrice di numerosi progetti finanziati da Enti Pubblici tra cui:
2020-2025: Regione Toscana, Bando Salute 2018
2015-2018: ENTE CASSA DI RISPARMIO DI FIRENZE
2013: ISTITUTO TOSCANO TUMORI - Regione Toscana
2002-2020: Fondi MIUR ex 60% - Università di Firenze
2006-2008: PRIN
2003-2005:Fondo FISR, CNR/MIUR:
2003-2005:Ministero Sanità, Ricerca Finalizzata
2001-2006:FIRB Progetti Autonomi 2001
2000:Agenzia CNR 2000:
1999:Progetto Strategico CNR
1998:CNR, Progetto Finalizzato: Biotecnologie

Socio ordinario fino al 2010 di Società Italiana di Immunologia, Immunologia Clinica ed
Allergologia (SIICA)
Socio ordinario di Società Italiana di Microbiologia (SIM)
Socio ordinario di American Society of Microbiology (ASM)
Attività di referaggio scientifico-editoriale per PROGETTI MIUR , VQR, ISS
Attività di referaggio per riviste scientifiche internazionali nel settore della Microbiologia,
Parassitologia, Immunologia

Esperienze lavorative
- Elevata esperienza nel settore della genomica microbica e caratterizzazione microbiota
- Elevata esperienza nel settore dell’immunologia cellulare e molecolare con particolare riguardo alla tipizzazione ed analisi funzionale di cellule del sistema immunitario in corso di malattie infettive e neoplastiche.
- Elevata esperienza nei settori della biochimica e biologia molecolare, citofluorimetria e microscopia confocale.
- Buona esperienza in Bioinformatica

Ottima conoscenza di software per scrittura, calcolo in ambiente Windows e Mac
Ottima conoscenza di software per analisi statistica e valorizzazione immagine.

Attivita’ di ricerca
2015-2025
A. Analisi metagenomica della flora vaginale batterica e fungina in corso di infezione con
Papilloma Virus (HPV 16-18): identificazione di co-fattori microbici correlati alla
persistenza dell’infezione e alla progressione neoplastica dell’epitelio cervicale
B. Identificazione di specie microbiche del microbiota vaginale che inibiscono i
meccanismi anti-virali e aumentano l’espressione di oncogeni di HPV 16/18
C. Meccanismi di “editing” del genoma di SARS-CoV-2
D. Analisi metagenomica della flora vaginale batterica e fungina in donne con fattori di
rischio per parto pretermine
E. Analisi metagenomica del microbiota seminale
F. Studio dell’interazione di ceppi di Klebsiella pneumoniae (KP)–KPC, di KP con
fenotipo ipermucoide e di E.coli-mcr con le cellule dell’immunità innata: identificazione
dei meccanismi molecolari che facilitano la colonizzazione e la diffusione.
G. Studio dei meccanismi infiammatori attivati da Parvo Virus B19 in monociti e fibroblasti
da soggetti sani o da pazienti con sclerodermia
H. Impatto delle infezioni virali sull’attività riproduttiva

2006 – 2015:
H. Valutazione degli effetti di radiazioni laser a bassa intensità su popolazioni di lieviti patogeni
I. Valutazione immunologica di gruppi etnici dell’Africa Subsahariana con diversa resistenza
all’infezione malarica.
L. Studio dei meccanismi di attivazione delle cellule T regolatorie nella risposta immunitaria al
Plasmodium falciparum, Leishmania infantum e Toxoplasma Gondii
M. Differenze di “gender” nella risposta immunitaria ad infezioni virali
N. Caratterizzazione degli effettori della risposta immunitaria ai lieviti

1984-2006
O. Definizione dei meccanismi molecolari di soppressione della risposta immunitaria tumorespecifica
P. Ruolo dei circuiti autocrini di crescita in neoplasie ematologiche e melanoma
Q. Meccanismi regolatori della crescita nelle cellule endoteliali
R. Meccanismi molecolari che regolano la sopravvivenza delle cellule di memoria nel sistema
Immunitario

Maria TORCIA

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Silvano, Angela; Sotillo, Javier; Cecchi, Marta; Loukas, Alex; Ouedraogo, Mireille; Parenti, Astrid; Bruschi, Fabrizio; Torcia, Maria Gabriella; Mangano, Valentina D (2024). Schistosoma heamatobium tetraspanins TSP-2 and TSP-6 induce Dendritic Cells maturation, cytokine production and T helper cells differentiation in vitro. MICROBES AND INFECTION, pp. 0-0, ISSN:1286-4579 DOI Accesso ONLINE all'editore

Dabizzi, Sara; Maggi, Mario; Torcia, Maria Gabriella (2024). Update on known and emergent viruses affecting human male genital tract and fertility. BASIC AND CLINICAL ANDROLOGY, vol. 34, pp. 6-6, ISSN:2051-4190 DOI

Angela Silvano , Niccolò Meriggi, Sonia Renzi, Viola Seravalli , Maria Gabriella Torcia , Duccio Cavalieri, Mariarosaria Di Tommaso (2023). Vaginal Microbiome in Pregnant Women with and without Short Cervix. NUTRIENTS, pp. 0-0, ISSN:2072-6643

Sabrina Nicolò; Alberto Antonelli; Michele Tanturli; Ilaria Baccani; Chiara Bonaiuto; Giuseppe Castronovo; Gian Maria Rossolini; G. Mattiuz; M. G. Torcia (2023). Bacterial Species from Vaginal Microbiota Differently Affect the Production of the E6 and E7 Oncoproteins and of p53 and p-Rb Oncosuppressors in HPV16-Infected Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 0-0, ISSN:1422-0067 DOI Accesso ONLINE all'editore

Marchiani S, Dabizzi S, Degl'Innocenti S, Fino MG, Torcia MG, Paoli D, Lombardo F, Ciccone N, Pollini S, Rossolini GM, Vignozzi L, Krausz C, Baldi E (2022). Safety issues in semen banks during the COVID-19 pandemic: data from a European survey. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol. 45, pp. 973-980, ISSN:1720-8386 DOI

Morselli S.; Sebastianelli A.; Liaci A.; Zaccaro C.; Pecoraro A.; Nicoletti R.; Manera A.; Bisegna C.; Campi R.; Pollini S.; Antonelli A.; Lagi F.; Coppi M.; Baldi E.; Marchiani S.; Nicolo S.; Torcia M.; Annunziato F.; Maggi M.; Vignozzi L.; Bartoloni A.; Rossolini G.M.; Serni S.; Gacci M. (2022). Male reproductive system inflammation after healing from coronavirus disease 2019. ANDROLOGY, vol. 10, pp. 1030-1037, ISSN:2047-2919 DOI Accesso ONLINE all'editore

Nicolò, Sabrina; Mattiuz, Giorgio; Antonelli, Alberto; Arena, Fabio; Di Pilato, Vincenzo; Giani, Tommaso; Baccani, Ilaria; Clemente, Ann Maria; Castronovo, Giuseppe; Tanturli, Michele; Cozzolino, Federico; Rossolini, Gian Maria; Torcia, Maria Gabriella (2022). Hypervirulent Klebsiella pneumoniae Strains Modulate Human Dendritic Cell Functions and Affect TH1/TH17 Response. MICROORGANISMS, vol. 10, pp. 384-384, ISSN:2076-2607 DOI

Nicolo S.; Tanturli M.; Mattiuz G.; Antonelli A.; Baccani I.; Bonaiuto C.; Baldi S.; Nannini G.; Menicatti M.; Bartolucci G.; Rossolini G.M.; Amedei A.; Torcia M.G. (2021). Vaginal lactobacilli and vaginal dysbiosis-associated bacteria differently affect cervical epithelial and immune homeostasis and anti-viral defenses. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 0-0, ISSN:1661-6596 DOI

Marchiani S.; Baccani I.; Tamburrino L.; Mattiuz G.; Nicolo S.; Bonaiuto C.; Panico C.; Vignozzi L.; Antonelli A.; Rossolini G.M.; Torcia M.; Baldi E. (2021). Author Correction: Effects of common Gram-negative pathogens causing male genitourinary-tract infections on human sperm functions (Scientific Reports, (2021), 11, 1, (19177), 10.1038/s41598-021-98710-5). SCIENTIFIC REPORTS, vol. 11, pp. 0-0, ISSN:2045-2322 DOI

Gacci M.; Coppi M.; Baldi E.; Sebastianelli A.; Zaccaro C.; Morselli S.; Pecoraro A.; Manera A.; Nicoletti R.; Liaci A.; Bisegna C.; Gemma L.; Giancane S.; Pollini S.; Antonelli A.; Lagi F.; Marchiani S.; Dabizzi S.; Nicolo S.; Torcia M.; Degl'innocenti S.; Annunziato F.; Maggi M.; Vignozzi L.; Bartoloni A.; Rossolini G.M.; Serni S. (2021). Reply: COVID-19: Semen impairment may not be related to the virus. HUMAN REPRODUCTION, vol. 36, pp. 2065-2066, ISSN:0268-1161 DOI

Sara Marchiani, Ilaria Baccani, Lara Tamburrino, Giorgio Mattiuz, Sabrina Nicolò, Chiara Bonaiuto, Carmen Panico, Linda Vignozzi, Alberto Antonelli, Gian maria Rossolini, Maria Torcia, Elisabetta Baldi (2021). Effects of common gram‑negative pathogens causing male genitourinary‑tract infections on human sperm functions. SCIENTIFIC REPORTS, pp. 0-0, ISSN:2045-2322 DOI

Monica Di Paola; Viola Seravalli; Sara Paccosi; Carlotta Linari; Astrid Parenti; Carlotta De Filippo; Michele Tanturli; Francesco Vitali; Maria Gabriella Torcia; Mariarosaria Di Tommaso (2020). Identification of Vaginal Microbial Communities Associated with Extreme Cervical Shortening in Pregnant Women. JOURNAL OF CLINICAL MEDICINE, vol. 9, pp. 3621-3636, ISSN:2077-0383 DOI Accesso ONLINE all'editore

Mattiuz, Giorgio; Nicolò, Sabrina; Antonelli, Alberto; Giani, Tommaso; Baccani, Ilaria; Cannatelli, Antonio; Clemente, Ann Maria; Castronovo, Giuseppe; Tanturli, Michele; Cozzolino, Federico; Rossolini, Gian Maria; Torcia, Maria Gabriella (2020). mcr-1 gene expression modulates the inflammatory response of human macrophages to Escherichia coli. INFECTION AND IMMUNITY, pp. 0-0, ISSN:0019-9567 DOI

Salvatore Di Giorgio, Filippo Martignano, Maria Gabriella Torcia, Giorgio Mattiuz, Silvestro Conticello (2020). Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2. SCIENCE ADVANCES, pp. 0-0, ISSN:2375-2548 DOI

Torcia M.G. (2019). Interplay among vaginal microbiome, immune response and sexually transmitted viral infections. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 266-266, ISSN:1661-6596 DOI Accesso ONLINE all'editore

Zakrzewska K.; Arvia R.; Torcia M.G.; Clemente A.M.; Tanturli M.; Castronovo G.; Sighinolfi G.; Giuggioli D.; Ferri C. (2019). Effects of Parvovirus B19 In Vitro Infection on Monocytes from Patients with Systemic Sclerosis: Enhanced Inflammatory Pathways by Caspase-1 Activation and Cytokine Production. JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 139, pp. 0-0, ISSN:0022-202X DOI Accesso ONLINE all'editore

Medelin, M.; Giacco, V.; Aldinucci, A.; Castronovo, G.; Bonechi, E.; Sibilla, A.; Tanturli, M.; Torcia, M.; Ballerini, L.*; Cozzolino, F.; Ballerini, C. (2018). Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro. MOLECULAR BRAIN, vol. 11, pp. 3-16, ISSN:1756-6606 DOI Accesso ONLINE all'editore

Ignacio Celestino; Paola Checconi; Donatella Amatore; Marta De Angelis; Paolo Coluccio; Rosanna Dattilo; Danilo Alunni Fegatelli; Ann Maria Clemente; Paola Matarrese; Maria Gabriella Torcia; Romina Mancinelli; Caterina Loredana Mammola; Enrico Garaci; Anna Rita Vestri; Walter Malorni; Anna Teresa Palamara; Lucia Nencioni (2018). Differential redox state contributes to sex disparities in the response to influenza virus infection in male and female mice. FRONTIERS IN IMMUNOLOGY, vol. 9, pp. 1-17, ISSN:1664-3224 DOI

DI PAOLA, Monica; Cristina, Sani; Clemente, ANN MARIA; Iossa, Anna; Perissi, Eloisa; Castronovo, Giuseppe; Tanturli, Michele; RIVERO GUEDEZ, DAMARIZ COROMOTO; Cozzolino, Federico; Cavalieri, Duccio; Carozzi, Francesca; DE FILIPPO, Carlotta; Torcia, Maria (2017). Characterization of cervico-vaginal microbiota in women developing persistent high-risk Human Papillomavirus infection. SCIENTIFIC REPORTS, vol. 7:10200, pp. 0-0, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Clemente, Ann Maria; Castronovo, Giuseppe; Antonelli, Alberto; D'Andrea, Marco Maria; Tanturli, Michele; Perissi, Eloisa; Paccosi, Sara; Parenti, Astrid; Cozzolino, Federico; Rossolini, Gian Maria; Torcia, Maria (2017). Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase. PLOS ONE, vol. 12, pp. 0-0, ISSN:1932-6203 DOI

Castronovo, Giuseppe; Clemente, Ann Maria; Antonelli, Alberto; D'Andrea, Marco Maria; Tanturli, Michele; Perissi, Eloisa; Paccosi, Sara; Parenti, Astrid; Cozzolino, Federico; Rossolini, Gian Maria; Torcia, Maria (2017). Differences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases. PLOS ONE, vol. 12, pp. e0170125-e0170141, ISSN:1932-6203 DOI Accesso ONLINE all'editore

Russo, Edda; Lombardelli, Letizia; Giudici, Francesco; Cavalli, Tiziana; Ficari, Ferdinando; Fazi, Marilena; Scaringi, Stefano; Biancone, Livia; Logiodice, Federica; Nesi, Mariateresa; Latiano, Anna; Annese, Vito; Torcia, Maria; Bechi, Paolo; Tonelli, Francesco; Piccinni, Marie-Pierre; Malentacchi, Cecilia (2017). Crohn's Colitis: Development of a multiplex gene expression assay comparing mRNA levels of susceptibility genes. CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, vol. 41, pp. 435-444, ISSN:2210-7401 DOI Accesso ONLINE all'editore

Clemente, A.M; Rizzetto, L.; Castronovo, G.; Perissi, E.; Tanturli, M.; Cozzolino, F.; Cavalieri, D.; Fusi, F.; Cialdai, F.; Vignali, L.; Torcia, M.G.; Monici, M. (2015). Effects of near-infrared laser radiation on the survival and inflammatory potential of Candida spp. involved in the pathogenesis of chemotherapy-induced oral mucositis. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, vol. 34, pp. 1999-2007, ISSN:0934-9723 DOI Accesso ONLINE all'editore

Anna Maria Clemente; Alberto Antonelli; Marco Maria D’Andrea; Gian Maria Rossolini; Maria Gabriella Torcia (2014). High inflammatory potential and reduced regulatory T cells differentiation of selected KPC-Klebsiella pneumoniae (Kp) strains compared to non KPC-producing Kp. In: 42° Congresso Nazionale della Società Italiana di Microbiologia, Torino, 28/09-01/10/2014, Società Italiana di Microbiologia, pp. 0-0.

Ann Maria Clemente; Carlo Severini; Giuseppe Castronovo; Michele Tanturli; Federico Cozzolino; Maria Torcia (2014). Effects of soluble extracts from Leishmania infantum promastigotes, Toxoplasma gondii tachyzoites on TGF-β mediated pathways in activated CD4+ T lymphocytes.. MICROBES AND INFECTION, vol. 14, pp. 102-106, ISSN:1286-4579 DOI

Sara Paccosi; Claudia Musilli; Roberto Caporale; Anna Maria Grazia Gelli; Daniele Guasti; Ann Maria Clemente; Maria Torcia; Amelia Filippelli; Paolo Romagnoli; Astrid Parenti (2014). Stimulatory interactions between human coronary smooth muscle cells and dendritic cells. PLOS ONE, vol. 9(6), pp. e99652-e99652, ISSN:1932-6203 DOI

Ann Maria Clemente; Carlo Severini; Giuseppe Castronovo; Michele Tanturli; Eloisa Perissi; Federico Cozzolino; MAria Gabriella Torcia (2014). Effects of soluble extracts from leishmania infantum promastigotes, toxoplasma gondii tachyzoites on TGF-β mediated pathways in activated CD4+ T lymphocytes.. MICROBES AND INFECTION, vol. 16, pp. 778-787, ISSN:1286-4579 DOI Accesso ONLINE all'editore

Paolo Romagnoli; Astrid Parenti; Sara Paccosi; Amelia Filippelli; Roberto Caporale; Ann Maria Clemente; Maria Gabriella Torcia; Angela Silvano (2014). Inflammatory mechanisms in the pathogenesis of cardiovascular Disease. In: 30th LIAC Meeting on Vascular Research, Valladolid (SPAIN), 22-25 october 2014, LIAC.The Latin Society for Vascular Research), pp. 37-38.

A. M. Clemente;G. Fadigati;R. Caporale;D. G. Marchese;G. Castronovo;A. R. Sannella;C. Severini;F. Verra;E. Garaci;F. Cozzolino;M. G. Torcia (2013). Modulation of the Immune and Inflammatory Responses by Plasmodium falciparum Schizont Extracts: Role of Myeloid Dendritic Cells in Effector and Regulatory Functions of CD4+ Lymphocytes. INFECTION AND IMMUNITY, vol. 81, pp. 1842-1851, ISSN:0019-9567 DOI

G. S. Sanou; R. W. Tiendrebeogo; A. L. Ouedraogo; A. Diarra; A. Ouedraogo; J. B. Yaro; E. Ouedraogo; F. Verra; C. Behr; M. Troye-Blomberg; D. Modiano; A. Dolo; M. G. Torcia; Y. Traore; S. B. Sirima; I. Nebie. (2012). Haematological parameters, natural regulatory CD4+CD25+FOXP3+ T cells and gammadelta T cells among two sympatric ethnic groups having different susceptibility to malaria in Burkina Faso. BMC RESEARCH NOTES, vol. %, pp. 0-0, ISSN:1756-0500

M. Torcia; L. Nencioni; A. M. Clemente; L. Civitelli; I. Celestino; D. Limongi; G. Fadigati; E. Perissi; F. Cozzolino; E. Garaci; A. Palamara (2012). Gender differences in the response to viral infections: TLR8 and TLR9 ligand stimulation induce higher IL10 production in males. PLOS ONE, vol. 7, pp. 0-0, ISSN:1932-6203 DOI

D. Scarpi; D. Cirelli; C. Matrone; G. Castronovo; P. Rosini; E. G. Occhiato; F. Romano; L. Bartali; A. M. Clemente; G. Bottegoni; A. Cavalli; G. De Chiara; P. Bonini; P. Calissano; A. T. Palamara; E. Garaci; M. G. Torcia; A. Guarna; F. Cozzolino (2012). Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity. CELL DEATH & DISEASE, vol. 3, pp. 0-0, ISSN:2041-4889 DOI

F. Nunnari; E. Gerace; D. Cirelli; E. Landucci; G. Castronovo; S. Bono; E. Perissi; M. G. Torcia; A. Guarna; D. E. Pellegrini-Giampietro; F. Cozzolino (2012). Nerve Growth Factor mimetics with neuroprotective activity in ischemic brain damage. In: Convegno Monotematico S.I.F, Urbino, 22-23 giugno 2012, Società Italiana Farmacologia, pp. 0-1.

Clemente A; Caporale R; Sannella AR; Majori G; Severini C; Fadigati G; Cirelli D; Bonini P; Garaci E; Cozzolino F; Torcia M (2011). Plasmodium falciparum soluble extracts potentiate the suppressive function of polyclonal T regulatory cells through activation of TGFβ-mediated signals.. CELLULAR MICROBIOLOGY, vol. 13, pp. 1328-1338, ISSN:1462-5814 DOI Accesso ONLINE all'editore

A. M. Clemente; F. Cozzolino; C. Severini; E. Garaci; M. G. Torcia (2011). Meccanismi di attivazione ed espansione delle cellule T regolatorie nell'infezione da P. Falciparum. In: Società Italiana di Microbiologia, 3-6/10/2011, non noto, pp. 36-36.

M. G. Torcia (2011). Mechanisms regulating expansion of polyclonal Treg populations and increase of their suppressive function mediated by P. falciparum proteins. FIGHTMAL: Correlating protection against malaria with serum profiles against Plasmodium falciparum antigen repertoires.. In: London School of Hygiene & Tropical Medicine, London, pp. 0-0.

C. M. Scimia; D. Scarpi, D. Cirelli, F. Romano, J. Francalanci, M. G. Torcia, E. Garaci, A. Guarna, G. Condorelli, F. Cozzolino (2010). Nerve Growth Factor mimetics reduce infarct size and functional damage upon coronary artery ligation in mice. In: Cardiovascular Development and Repair - Keystone Symposia, Keystone - Colorado - USA, 28/2-5/3/2010, Keystone Symposia, pp. 0-0.

D. Cavalieri; D. Rivero; L. Beltrame; S. I. Buschow; E. Calura; L. Rizzetto; S. Gessani; M. C. Gauzzi; W. Reith; A. Baur; R. Bonaiuti; M. Brandizi; C. De Filippo; U. D'Oro; S. Draghici; I. Dunand-Sauthier; E. Gatti; F. Granucci; M. Gündel; M. Kramer; M. Kuka; A. Lanyi; C. J. Melief; N. van Montfoort; R. Ostuni; P. Pierre; R. Popovici; E. Rajnavolgyi; S. Schierer; G. Schuler; V. Soumelis; A. Splendiani; I. Stefanini; M. G. Torcia; I. Zanoni; R. Zollinger; C. G. Figdor; J. M. Austyn (2010). DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells.. IMMUNOME RESEARCH, vol. 6, pp. 0-0, ISSN:1745-7580 DOI

L. Rizzetto; M. Kuka; C. De Filippo; A. Cambi; M. G. Netea; L. Beltrame; G. Napolitani; M. Torcia; U. D'Oro; D. Cavalieri (2010). Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism. JOURNAL OF IMMUNOLOGY, vol. 184, pp. 4258-4268, ISSN:0022-1767

L. Nencioni; G. De Chiara; R. Sgarbanti; D. Amatore; K. Aquilano; M. E. Marcocci; A. Serafino; M. Torcia; F. Cozzolino; M. R. Ciriolo; E. Garaci; A. T. Palamara (2009). Bcl-2 expression and p38MAPK activity in cells infected with influenza A virus: impact on virally induced apoptosis and viral replication. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284, pp. 16004-16015, ISSN:0021-9258

A. Guarna; F. Cozzolino; M. Torcia; E. Garaci (2009). Pharmaceutical compositions for the treatment of diseases related to neurotrophines. Numero: US Patent 7625892 Minerva Patents SA

M. G. Torcia (2008). Meccanismi di soppressione della risposta immunitarianell’infezione da Plasmodium falciparum: ruolo dell’immunità innata e specifica.. In: 36° Congresso della Società Italiana di Microbiologia, pp. 0-0.

A. M. Clemente; C. Severini; A. Sannella; G. Maiori; R. Caporale; F. Cozzolino; D. Modiano; M. G. Torcia (2008). TLR5 is involved in enhancing suppressive capacity and FOXP3 expression of CD4+CD25+ Tregulatory cells during an immune response “in vitro” to P. falciparum malaria. In: INTERNATIONAL CONGRESS ON CYTOKINES IN IMMUNE REGULATION AND DISEASE, Cytokines, pp. 0-0.

A. BONACCHI; ML TADDEI ; I PETRAI ;E EFSEN ; R. DEFRANCO ; D. NOSI ; M. TORCIA; P. ROSINI ; L. FORMIGLI ; K. ROMBOUTS ; S. ZECCHI; S. MILANI ; M. PINZANI ; G. LAFFI ; F. MARRA (2008). Nuclear localization of TRK-A in liver cells.. HISTOLOGY AND HISTOPATHOLOGY, vol. 23, pp. 327-340, ISSN:0213-3911

Torcia, Maria; Santarlasci, Veronica; Cosmi, Lorenzo; Clemente, Annamaria; Maggi, Laura; Mangano, Valentina ; Verra, Federica; Bancone, Germana; Nebie, Issa; Sirima, Bienvenu Sodiomon; Liotta, Francesco; Frosali, Francesca; Angeli, Roberta; Severini, Carlo; Sannella, Anna R.; Bonini, Paolo; Lucibello, Maria; Maggi, Enrico; Garaci, Enrico; Coluzzi, Mario; Cozzolino, Federico; Annunziato, Francesco; Romagnani, Sergio; Modiano, David (2008). Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105, pp. 646-651, ISSN:0027-8424 DOI

DE CHIARA G; MARCOCCI ME; TORCIA M; LUCIBELLO M; ROSINI P; BONINI P; HIGASHIMOTO Y; DAMONTE G; ARMIROTTI A; AMODEI S; PALAMARA AT; RUSSO T; GARACI E; F. COZZOLINO (2006). Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281, pp. 21353-21361, ISSN:0021-9258

M. Torcia (2006). Nerve growth factor as a vaccine adjuvant. Numero: US Patent 6572866 Minerva Patents SA

ROSINI P; DE CHIARA G; BONINI P; LUCIBELLO M; MARCOCCI ME; GARACI E; F. COZZOLINO; TORCIA M (2004). Nerve growth factor-dependent survival of CESS B cell line is mediated by increased expression and decreased degradation of MAPK phosphatase 1.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, pp. 14016-14023, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824:

ROSINI P; DE CHIARA G; BONINI P; LUCIBELLO M; MARCOCCI ME; GARACI E; COZZOLINO F; M. TORCIA (2004). NGF-dependent survival of CESS B cell line is mediated by increased expression and decreased degradation of MKP-1.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, pp. 14016-14023, ISSN:0021-9258 DOI

E. Efsen; A. Bonacchi; I. Petrai; P. Rosini; M. Torcia; M. Pinzani; P. Gentilini; F. Marra (2002). NGF and Trk-A as a novel autocrine loop in the early stages of hepatic stellate cell (HSC) activation. JOURNAL OF HEPATOLOGY, vol. 36, pp. 70-70, ISSN:0168-8278

ROSINI P; BONACCORSI L; BALDI E; CHIASSERINI C; G. FORTI; DE CHIARA G; LUCIBELLO M; MONGIAT M; IOZZO RV; GARACI E; COZZOLINO F; TORCIA M (2002). Androgen receptor expression induces FGF2, FGF-binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth, survival, and androgen receptor down-modulation.. THE PROSTATE, vol. 53(4), pp. 310-321, ISSN:0270-4137, John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551:

M. Torcia; G. De Chiara; L. Nencioni; S. Ammendola; D. Labardi; M. Lucibello; P. Rosini; L. N. J.; P. Bonini; P. Dello Sbarba; A. T. Palamara; N. Zambrano; T. Russo; E. Garaci; F. Cozzolino (2001). Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, pp. 39027-39036, ISSN:0021-9258

TORCIA M; DE CHIARA G; NENCIONI L; AMMENDOLA S; LABARDI D; LUCIBELLO M; ROSINI P; MARLIER LN; BONINI P; DELLO SBARBA P; PALAMARA AT; ZAMBRANO N; RUSSO T; GARACI E; F. COZZOLINO (2001). NGF inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation and cytochrome c release.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, pp. 39027-39036, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824:

ROSINI P; DE CHIARA G; LUCIBELLO M; GARACI E; F. COZZOLINO; TORCIA M (2000). NGF withdrawal induces apoptosis in CESS B cell line through p38 MAPK activation and Bcl-2 phosphorylation.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 278, pp. 753-759, ISSN:0006-291X, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445:

M. Torcia; G. De Chiara; P. Rosini; L. Nencioni; M. Lucibello; E. Garaci; F. Cozzolino (2000). Nerve Growth Factor inhibits apoptosis via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation and cytochrome c release. MOLECULAR BIOLOGY OF THE CELL, vol. 11, pp. 38A-38A, ISSN:1059-1524

TORCIA M; LUCIBELLO M; DE CHIARA G; LABARDI D; NENCIONI L; BONINI P; GARACI E; F. COZZOLINO (1999). Interferon-alpha-induced inhibition of B16 melanoma cell proliferation:interference with the bFGF autocrine growth circuit.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 262, pp. 838-844, ISSN:0006-291X, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445:

M. Torcia; M. Lucibello; E. Vannier; S. Fabiani; A. Miliani; G. Guidi; O. Spada; S. K. Dower; J. E. Sims; A. R. Shaw; C. A. Dinarello; E. Garaci; F. Cozzolino (1996). Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. EXPERIMENTAL HEMATOLOGY, vol. 24, pp. 868-868, ISSN:0301-472X

Torcia M; Bracci Laudiero L; Lucibello M; Nencioni L; Labardi D; Rubartelli A; Cozzolino F; Aloe L; Garaci E. (1996). Nerve growth factor is an autocrine survival factor for memory B lymphocytes. CELL, vol. 85, pp. 345-356, ISSN:0092-8674, Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850:

KUWABARA K; OGAWA S; MATSUMOTO M; KOGA S; CLAUSS M; PINSKY D; WITTE L; JOSEPH-SILVERSTEIN J; FURIE M; KAMADA T; TORCIA M; F. COZZOLINO; STERN D (1995). Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 92, pp. 4606-4610, ISSN:0027-8424, National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525:

A. RAMBALDI; R. SCHIRO; M. TORCIA; C. A. DINARELLO; T. BARBUI; F. COZZOLINO; G. MASERA; A. BIONDI (1994). Autocrine and paracrine growth-factors in leukemia-cell proliferation. In: International Symposium on Molecular Diagnosis and Monitoring of Leukaemia and Lymphoma, Perugia, APR 15-17, 1993, vol. 2, pp. 189-196.

RAMBALDI A; TORCIA M; DINARELLO CA; BARBUI T; F. COZZOLINO (1993). Modulation of cell proliferation and cytokine production in AML by recombinant interleukin-1 receptor antagonist.. LEUKEMIA, vol. 7, pp. 10-12, ISSN:0887-6924, Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358:

Cozzolino F.; Torcia M.; Lucibello M.; Morbidelli L.; Ziche M.; Platt J.; Fabiani S.; Brett J.; Stern D. (1993). Cytokine-mediated control of endothelial cell growth: interferon-* and interleukin-2 synergistically enhance basic fibroblast growth factor synthesis and induce release, promoting cell growth in vitro and in vivo.. THE JOURNAL OF CLINICAL INVESTIGATION, vol. 91, pp. 2504-2512, ISSN:0021-9738

M. TORCIA; M. LUCIBELLO; E. VANNIER; S. FABIANI; C. A. DINARELLO; F. COZZOLINO (1992). TRANSFORMING GROWTH-FACTOR-BETA INDUCES SYNTHESIS AND SECRETION OF INTERLEUKIN-1 RECEPTOR ANTAGONIST IN ACUTE MYELOID-LEUKEMIA CELLS. In: 2ND INTERNATIONAL CONGRESS ON CYTOKINES : BASIC PRINCIPLES AND CLINICAL APPLICATIONS, Firenze, MAR 23-25, 1992, vol. 92, pp. 61-66.

F. COZZOLINO; M. TORCIA; M. ZICHE; M. LUCIBELLO; J. BRETT; J. PLATT; D. STERN (1992). CYTOKINE CONTROL OF ENDOTHELIAL-CELL (EC) GROWTH - ALPHA-INTERFERON (ALPHA-IFN) AND INTERLEUKIN-2 (IL-2) SYNERGISTICALLY ENHANCE BASIC FIBROBLAST GROWTH-FACTOR (BFGF) SYNTHESIS AND INDUCE SECRETION PROMOTING CELL-GROWTH INVITRO AND INVIVO. CLINICAL RESEARCH, vol. 40, pp. 186-186, ISSN:0009-9279

SHREENIWAS R; OGAWA S; F. COZZOLINO; TORCIA M; BRAUNSTEIN N; BUTURA C; BRETT J; LIEBERMAN HB; FURIE M; JOSEPH-SILVERSTEIN J; STERN D (1991). Macrovascular and microvascular endothelium during long-term hypoxia: alterations in cell growth, monolayer permeability, and cell surface coagulant properties.. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 146, pp. 8-17, ISSN:0021-9541, John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551:

RAMBALDI A; TORCIA M; BETTONI S; VANNIER E; BARBUI T; SHAW AR; DINARELLO CA; F. COZZOLINO (1991). Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells.. BLOOD, vol. 78, pp. 3248-53, ISSN:0006-4971, American Society of Hematology:1900 M Street Northwest, Suite 200:Washington, DC 20036:(800)633-4931, (202)776-0544, EMAIL: publishing@hematology.org, ash@hematology.org, INTERNET: http://www.hematology.org, Fax: (202)776-0551:

F. COZZOLINO; G. TORCIA; M. ZICHE; S. OGAWA; J. BRETT; S. KOGA; H. VLASSARA; P. NAWROTH; D. STERN (1990). Advanced Glycosylation End-Products (Ages) Stimulate Endothelial-Cell (Ec) Growth-Invitro And Invivo. CIRCULATION, vol. 82, pp. 36-36, ISSN:0009-7322

F. COZZOLINO; TORCIA M; BETTONI S; ALDINUCCI D; BURGIO VL; RUBARTELLI A; BARBUI T; RAMBALDI A (1990). Interleukin-1 and interleukin-2 control granulocyte- and granulocyte-macrophage colony-stimulating factor gene expression and cell proliferation in cultured acute myeloblastic leukemia.. INTERNATIONAL JOURNAL OF CANCER, vol. 46, pp. 902-907, ISSN:0020-7136, John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551:

F.Cozzolino; M.Torcia; D.Aldinucci; M.Ziche; F.Almerigogna; D.Bani; DM.Stern (1990). Interleukin 1 is an autocrine regulator of human endothelial cell growth.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 87, pp. 6487-6491, ISSN:0027-8424

Cozzolino F.; Torcia M.; Aldinucci D.; Gallo O.; Gallina E.; Talini G.; Fini Storchi O. (1989). Meccanismi di soppressione della risposta immunitaria antitumorale in linfonodi metastatici di pazienti con carcinoma della laringe. L'immunoterapia dei tumori della testa e del collo. pp. 25-28

TORCIA M; ALDINUCCI D; CAROSSINO A.M.; IMREH F; COZZOLINO F. (1989). Biologic and clinical significance of cytokine production in B-cell malignancies. EUROPEAN JOURNAL OF HAEMATOLOGY, vol. 51, pp. 35-42, ISSN:0902-4441

F. COZZOLINO; RUBARTELLI A; ALDINUCCI D; SITIA R; TORCIA M; SHAW AR; DI GUGLIELMO R (1989). Interleukin 1 as an autocrine growth factor for acute myeloid leukemia cells.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 86, pp. 2369-2373, ISSN:0027-8424, National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525:

MAY LT; TORCIA M; F. COZZOLINO; RAY A; TATTER SB; SANTHANAM U; SEHGAL PB; STERN DM (1989). Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 159, pp. 991-998, ISSN:0006-291X, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445:

F. COZZOLINO; TORCIA M; ALDINUCCI D; RUBARTELLI A; MILIANI A; SHAW AR; LANSDORP PM; DI GUGLIELMO R (1989). Production of interleukin-1 by bone marrow myeloma cells.. BLOOD, vol. 74, pp. 380-387, ISSN:0006-4971, American Society of Hematology:1900 M Street Northwest, Suite 200:Washington, DC 20036:(800)633-4931, (202)776-0544, EMAIL: publishing@hematology.org, ash@hematology.org, INTERNET: http://www.hematology.org, Fax: (202)776-0551:

AMATO M; BERGESIO F; SALVADORI M; F. COZZOLINO; TORCIA M; HIMMELFARB J (1989). In vitro cytokine production induced by different dialysis membranes and by anaphylatoxins C3a and C5a.. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol. 12, pp. 112-117, ISSN:0391-3988, Wichtig Editore:Via Friuli 72 74, I 20135 Milan Italy:011 39 02 5455122, 011 39 2 55195443, EMAIL: info@wichtig-publisher.com, INTERNET: http://www.wichtig-publisher.com, Fax: 011 39 2 55195971:

AMATO M; COZZOLINO F; BERGESIO F; SALVADORI M; TORCIA M.G.; CAROSSINO A.M. ; SODI A. (1988). In vitro interleukin-1 production by different dialysis membranes.. NEPHROLOGY DIALYSIS TRANSPLANTATION, vol. 3, pp. 432-434, ISSN:0931-0509, Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485:

COZZOLINO F; TORCIA M; MILIANI A; CAROSSINO A.M. ; GIORDANI R; CINOTTI S; FILIMBERTI E; SACCARDI R; BERNABEI P; GUIDI G; ET AL. (1988). Potential role of interleukin-1 as the trigger for diffuse intravascular coagulation in acute nonlymphoblastic leukemia.. THE AMERICAN JOURNAL OF MEDICINE, vol. 84, pp. 240-250, ISSN:0002-9343, Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680:

Selli C.; Torcia M.; Carini M.; Carossino A.M.; Cozzolino F (1987). Produzione di citochine in vitro da parte del carcinoma renale.. In: Atti del XIII Congresso Nazionale della Società Italiana di Ricerche in Chirurgia, pp. 353-356.

F. COZZOLINO; TORCIA M; DI GUGLIELMO R (1987). Immunoregolazione in alcune forme di emopoiesi neoplastica.. HAEMATOLOGICA, vol. 72, pp. 301-304, ISSN:0390-6078, Fondaz Ferrata Storti:Strada Nuova 134, 27100 Pavia Italy:011 39 0382 531182, EMAIL: office@haematologica.it, Fax: 011 39 0382 27721:

F. COZZOLINO; M. TORCIA; M. FERRARINI; R. DIGUGLIELMO; P. P. NAWROTH; D. M. STERN (1987). ACUTE MYELOID-LEUKEMIA CELL-DERIVED INTERLEUKIN-1 AND DIFFUSE INTRAVASCULAR COAGULATION. In: CONF ON CELLULAR BLOOD COMPONENTS IN HAEMOSTASIS AND THROMBOSIS : IMPLICATIONS FROM MYELOPROLIFERATIVE DISORDERS, Bergamo, MAY 07-08, 1987, CONF ON CELLULAR BLOOD COMPONENTS IN HAEMOSTASIS AND THROMBOSI, vol. 1, pp. 97-103.

COZZOLINO F.; TORCIA M.; CAROSSINO A.M.; GIORDANI R.; SELLI C.; TALINI G.; REALI E.; NOVELLI A.; PISTOIA V.; FERRARINI M. (1987). Characterization of cells from invaded lymph nodes in patients with solid tumors. Lymphokine requirement for tumor-specific lymphoproliferative response.. JOURNAL OF EXPERIMENTAL MEDICINE, vol. 166, pp. 303-318, ISSN:0022-1007, Rockefeller University Press:1114 First Avenue, Fourth Floor:New York, NY 10021:(212)327-8572, EMAIL: rupcd@rockvax.rockefeller.edu, INTERNET: http://www.rockefeller.edu/rupress, Fax: (212)327-7944:

M. Torcia; A. Rubartelli; A. Shaw; F. Cozzolino (1987). Interleukin-1 production by multiple-myeloma cells. JOURNAL OF LEUKOCYTE BIOLOGY, vol. 42, pp. 590-591, ISSN:0741-5400

COZZOLINO F; TORCIA M; CASTIGLI E; SELLI C; GIORDANI R; CAROSSINO A.M.; SQUADRELLI M; CAGNONI M; PISTOIA V; FERRARINI M. (1986). Presence of activated T-cell with a T8+M1+Leu7+ surface phenotype in invaded lymph nodes from patients with solid tumors. JOURNAL OF THE NATIONAL CANCER INSTITUTE, vol. 77, pp. 637-641, ISSN:0027-8874, Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485:

PISTOIA V; F. COZZOLINO; RUBARTELLI A; TORCIA M; RONCELLA S; FERRARINI M (1986). In vitro production of interleukin 1 by normal and malignant human B lymphocytes.. JOURNAL OF IMMUNOLOGY, vol. 136, pp. 1688-1692, ISSN:0022-1767, American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099:

PISTOIA V; F. COZZOLINO; TORCIA M; CASTIGLI E; FERRARINI M (1985). Production of B cell growth factor by a Leu-7+, OK M1+ non-T cell with the features of large granular lymphocytes.. JOURNAL OF IMMUNOLOGY, vol. 134, pp. 3179-3184, ISSN:0022-1767, American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099:

B. Neri; T. Comparini; G. Torcia; M. Tommasi; S. Bacalli; A. Ciapini (1984). Assessment of Phosphohexose-isomerase, Beta2-microgubulin and Ferritin in lung cancer. LABORATORY MEDICINE, vol. 11, pp. 9-12, ISSN:0007-5027

B. Neri; M. Torcia; t. Comparini; S. Guidi; A. Milani; A. Ciapini (1983). Creatine Kinase MB: A non invasive test monitoring acute adriamycin and daunomycin cardiotoxicity. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, vol. 2, pp. 41-45, ISSN:0392-9078

B. Neri; T. Comparini; M. Torcia; A. Ciapini (1983). Prevention of adriamycin and daunomycin cardiotoxicity in cancerous patiens by L-Carnitine. In: XIII International Congress of Chemotherapy, 1983, vol. Proceedings XIII International Congress of Chemotherapy, pp. 49-53.

B. Neri; T. Comparini; A. Milani; M. Torcia; A. Ciapini (1983). Protective effects of L-carnitine on acute Adriamycin and Daunomycin cardiotoxicity in cancer patiens. CLINICAL TRIALS JOURNAL, vol. 20, pp. 98-103, ISSN:0009-9325

Maria TORCIA

Curriculum

FIRENZE 14.03.2025

Curriculum vitae
Prof. Maria, Gabriella Torcia,

Associate Professor in Microbiology (SSD MED/07)

Address: DIPARTIMENTO DI MEDICINA SPERIMENTALE E CLINICA - VIALE PIERACCINI 6 – 50139 FIRENZE
Telefono +39 3479966990
E-mail maria.torcia@unifi.it
Nazionalità: Italiana
Data di nascita: 24 marzo 1958

Teaching Activity
[B030939] - Microbiology –Medicine and Surgery,
[B016765] General Microbiology; B014 –Biotechnology

B230: - Microbiology : Dentistry

Clinical Activity: Andrology, Endocrinology and Gender Incongruence-AOU Careggi- Regional Reference Center for Cryopreservation of Seminal Fluid

Esperienza lavorativa
2010-2025 Associate Professor in Microbiology and Clinical Microbiology.(SSD MED/07)
Department of Experimental and Clinical Medicine;
Medical Doctor: SOD Andrology, Endocrinology and Gender Incongruence; Azienda Ospedaliero-Universitaria di Careggi, Firenze
2002-2010 Assistant Professor general medicine: Department of Experimental and Clinical Medicine;
1987-2002: Technical Officer, Università degli studi di Firenze
1986-1987: Scholarship Associazione Italiana per la Ricerca sul Cancro
1985-1986: Scholarship of the Ministero Pubblica Istruzione
per attività di ricerca presso Istituto di Clinica Medica IV, Università di Firenze
1981-1984: Specialization in General Hematology (Clinical and Laboratory): Qualification obtained with a grade of 70/70 laude
1981: Degree in Medicine and Surgery with a grade of 110/110 laude
1975: Scientific high school diploma with a grade of 60/60

Experiences abroad
1992-1993) Merck Sharp & Dohme Corp Research Laboratories, West Point, PA 19486(Screening di librerie fagiche)
1988-1990 Visiting Researcher at College of Physicians and Surgery, Department of Physiology and Cellular Biophysics, Columbia University, New York, NY

Expertise and experience in various research areas and in particular:
-Immunology
-Hematology
- Microbiology (pathogen/host interaction)

First language: ITALIAN
Other languages: ENGLISH SPANISH

Coordinator of numerous projects funded by Public Institutions including:
2020-2025: Regione Toscana, Bando Salute 2018
2015-2018: ENTE CASSA DI RISPARMIO DI FIRENZE
2013: ISTITUTO TOSCANO TUMORI - Regione Toscana
2002-2020: Fondi MIUR ex 60% - Università di Firenze
2006-2008: PRIN
2003-2005:Fondo FISR, CNR/MIUR:
2003-2005:Ministero Sanità, Ricerca Finalizzata
2001-2006:FIRB Progetti Autonomi 2001
2000:Agenzia CNR 2000:
1999:Progetto Strategico CNR
1998:CNR, Progetto Finalizzato: Biotecnologie

Ordinary member until 2010 of the Italian Society of Immunology, Clinical Immunology and Allergology (SIICA)
Ordinary member of the Italian Society of Microbiology (SIM)
Socio ordinario di American Society of Microbiology (ASM)
Scientific-editorial refereeing activities for MIUR, VQR, ISS PROJECTS
Referee for international scientific journals in the field of Microbiology, Parasitology, Immunology

Work experience
- High experience in the field of microbial genomics and microbiota characterization
- High experience in the field of cellular and molecular immunology with particular regard to the typing and functional analysis of cells of the immune system in the course of infectious and neoplastic diseases.
- High experience in the fields of biochemistry and molecular biology, flow cytometry and confocal microscopy.
- Good experience in Bioinformatics

Excellent knowledge of software for Windows and Mac environments
Excellent knowledge of software for statistical analysis and imageing

Research activities
2015-2025
A. Metagenomic analysis of bacterial and fungal vaginal flora during infection with Papilloma Virus (HPV 16-18): identification of microbial co-factors related to the persistence of infection and neoplastic progression of the cervical epithelium
B. Identification of microbial species of the vaginal microbiota that inhibit anti-viral mechanisms and increase the expression of HPV 16/18 oncogenes
C. Mechanisms of genome editing of SARS-CoV-2
D. Metagenomic analysis of bacterial and fungal vaginal flora in women with risk factors for preterm birth
E. Metagenomic analysis of seminal microbiota
F. Study of the interaction of Klebsiella pneumoniae (KP)–KPC strains with hypermucoid phenotype, and E.coli-mcr with innate immunity cells: identification of the molecular mechanisms that facilitate colonization and spread.
G. Study of the inflammatory mechanisms activated by Parvo Virus B19 in monocytes and fibroblasts in healthy subjects and patients with sclerodermia
H. Impact of viral infections on reproductive activity

2006 – 2015:
H. Evaluation of the effects of low-intensity laser radiation on pathogenic yeast populations
I. Immunological evaluation of ethnic groups from Sub-Saharan Africa with different resistance to malaria infection.
L. Study of the mechanisms of regulatory T cell activation in the immune response to Plasmodium falciparum, Leishmania infantum and Toxoplasma Gondii
M. Gender differences in the immune response to viral infections
N. Characterization of the effectors of the immune response to yeasts

1984-2006
O. Definition of the molecular mechanisms of suppression of the tumor-specific immune response
P. Role of autocrine growth circuits in hematologic malignancies and melanoma
Q. Growth regulatory mechanisms in endothelial cells
R. Molecular mechanisms that regulate the survival of memory cells in the immune system