Prima lezione di Chimica delle Biomolecole Lunedi 15 settembre 2025, 16:00-18:00 Aula 39 Blocco Aule

La lezione 1 del Corso di Chimica delle Biomolecole si svolgera' Lunedi 15/09/25, 16:00-18:00 in Aula 39 Blocco Aule. La lezione successiva si svolgerà Mercoledi 17/09/25 ore 9-11: Aula 39 Vi daro' anche informazioni su Erasmus+ Anna Maria Papini

Su appuntamento

e-mail: annamaria.papini@unifi.it

cell: 3478844146

skype contact: pepthome

Short biography

After completion of an International PhD degree in 1990, under the supervision of Professor Luis Moroder at the Max Planck Institute for Biochemistry, she launched in 1991 a comprehensive peptide-based translational research program and founded the first laboratory of peptide chemistry at the University of Florence. She was Associate Professor of Bioorganic Chemistry (2001-2019) and in 2020, she was appointed Full Professor at the University of Florence. She is Laureate of the “Chaire d’Excellence” 2009-2014 of the French “Agence Nationale de la Recherche” (unique for chemistry out of 16) for the project “PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases”. The project was developed at the Université Paris-Seine (now CY Cergy Paris Université), where she was appointed Full Professor of Bioorganic chemistry, founding and being Director of the platform PeptLab@UCP, born to support start-up companies involved in R&D of peptide-based products (2008-2020). In 2009, she started the French-Italian Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology (PeptLab) that she coordinates, associating the Departments of Chemistry and NeuroFarBa (Section of Pharmaceutical Sciences) of the University of Florence and PeptLab@UCP in France. In June 2019, at PeptLab@UCP, she launched a facility for large-scale production of peptides with the Liberty Pro MW-assisted synthesizer, the technology she trusted for its unique performances since she purchased, in 2005, the first MW-peptide synthesizer installed in Europe, at PeptLab at the University of Florence. In recognition of her outstanding contribution to peptide science, in 2008, she was the recipient of the Leonidas Zervas Award of the European Peptide Society and of the First Dimitrios Theodoropoulos Memorial Award of the Hellenic Peptide Society. She was awarded the Rita Levi Montalcini Prize 2019-2021 for the binational cooperation between Italy and Israel to develop her program aimed to characterise possible unknown bacterial and/or viral infections triggering immune-mediated diseases using aberrantly glycosylated peptide antigens and recognized with the Barry Cohen Prize 2024 for Medicinal Chemistry/Chemical Biology that was attributed by the Israel Chemical Society on July 18, 2024 at the Weizmann Institute of Science, Rehovot, after presenting a keynote lecture. She will be awarded with the Medal of the Polish Chemical Society during the award ceremony that will take place during the official opening of the 67th Scientific Meeting of the Polish Chemical Society on Monday, September 22, 2025 and on Wednesday September 24, 2025 she will deliver the plenary lecture to present her research. Since 2013, she is delegate of the International Affairs and Erasmus Program of the School of Mathematical, Physical, and Natural Sciences of the University of Florence supporting and orienting students interested in international education pathways and since 2021 she is Director of the Phd Programme in Chemical Sciences of the University of Florence, confirmed for a second term till 2027. She contributed to launch several double degrees in Chemical sciences for 2-year Masters (Hebrew University of Jerusalem, University of Burgos, Rouen Normandie, Paris Sciences et Lettres) and for PhDs (Wroclaw University of Science and Technology, University of Cergy-Pontoise, University of Rouen Normandie, Ecole Normale Supérieure-University Pierre et Marie Curie). She has been Treasurer and Member of the Executive Committee of the European Peptide Society (2011-2020) and still is Councillor of the American Peptide Society (2019-2025). In 2015, she was founding member of the Italian Peptide Society and she was appointed scientific officer of the executive committee since 2017. She organised several meetings, among them, she was chair with Phil E. Dawson of the 2016 Gordon Research Conference “Crossing Barriers by Peptide Science for Health and Wellness” and on August 25-31, 2024 she cochaired with Paolo Rovero the 14^th International Peptide Symposium/37^th European Peptide Symposium (www.eps2024.com) that took place at Palazzo dei Congressi in Florence (Italy) with 1049 participants from 45 countries and all the 5 continents. Three parallel workshops were organised at Plesso Didattico Morgagni of the University of Florence on Friday, August 30 and Saturday, August 31, right after the main symposium, on hot topics, i.e., 1) Applications of computational AI/ML in peptide research with a roadmap to peptide drug and material development; 2) Embracing innovation and sustainability in peptide synthesis; 3) Navigating entrepreneurship and technology transfer in peptide discovery and development (supported in part by EUniWell, Project TTpep: Technology Transfer of Peptides for the Well-being Economy). In 2003 she cofounded the first spin-off of the University of Florence, EspiKem Srl, that managed the valorisation of a peptide-based anti-aging cosmeceutical product, Definisse KP1, developed in her academic laboratories and launched on the global market on September 2023 by Relife, the aesthetic medicine division of Menarini group. Moreover, she cofounded and acted as CSO of the start-up Toscana Biomarkers Srl (2007-2014), with the R&D mission to innovate and licensing intellectual property of peptides for diagnostic kits of autoimmune diseases. Distinguished for activity in technology transfer, she received the 2009 Frost & Sullivan Excellence in Research Award in the European autoimmune disease diagnostics market and the Vespucci Award of the Region Toscana for the development of a company aimed to research and produce innovative peptide-based diagnostic methodologies for autoimmune diseases. In 2016, she founded and is Director of the Toscana EU-Region technology transfer Laboratory of Molecular Diagnostics and Life Sciences (MoD&LS) where she coordinated the standardisation of the HPLC-MS analyses of ca. 60 endocrine disrupting chemicals and their metabolites in more than 4000 biological fluids of children and their mothers (urines, sera and breast milk) to associate their presence with children disease development such as autism, obesity, and insulin resistance. Moreover, she has been scientific supervisor of the PeptLab and Fabbrica Italiana Sintetici Spa joint laboratory PeptFarm, for GMP large-scale peptide synthesis in Vicenza. Recently thanks to a cooperation with Protein Technologies AB (Sweden) she has been involved in a joint industrial PhD to develop sustainable strategies for peptide production with a holistic approach integrating green solvents and reagents, automatic peptide synthesizers and low impact purification platforms. She worked as panel member, evaluator and rapporteur for several funding European agencies (2012-2019 - Panel Member for ERC Advanced Grant evaluation PE5 – Synthetic chemistry and materials, REA HE-MSCA-PF-2018-2024; ESF-FWO 2018-2024), and national Agencies in Europe (Research Council of Lithuania 2018-2023; Polish National Science Centre 2018-2023, etc.) and in the world (CANADIAN INSTITUTES OF HEALTH RESEARCH, Israeli German Foundation, etc.) to select projects. She is coauthor (ORCID: 0000-0002-2947-7107) of 399 peer-reviewed publications indexed by WOS (ID: JAX-3042-2023, 05/02/2025), 212 indexed by Scopus (ID: 7005551589) and of 11 filed patents some of them licensed to companies, including the coupling reagents TBCRs . She presented worldwide 161 invited lectures in International Symposia, Universities, and Research Centres (31 aimed to technology transfer). Her laboratory has communicated 76 oral and 295 poster presentations at international symposia. In her independent career, she has trained 40 PhDs and 82 undergraduate students (55 M.Sc. and 27 B.Sc.), 16 post-doctoral fellows and 11 research assistants, with focus on the characterisation of aberrant post-translational modifications and biomarkers of immune-mediated diseases, structure-activity relationship studies, and efficient synthetic strategies for metabolic stabilization by strategic side-chain to side-chain cyclization. Her PhD students have received important distinctions, including the 2024 XX Edition of Antonio Bardazzi Award 2023, “Sara Lapi” Award for the Best Master Theses in Chemistry, the 2016 Louis Forest “Prix de la Chancellerie des Universités de Paris”, the 2005 Bert Schram Young Investigator Honorable Mention, and the 1999 Bruce W. Erickson Award from the American Peptide Society.

Anna Maria Papini is married and has two daughters (Giulia 09/05/1991 and Elena 10/04/1996)

Firenze (Italy), February 5, 2025

ANNA MARIA PAPINI

Professore Ordinario di Chimica Bioorganica, Dottore di Ricerca in Scienze Chimiche

Curriculum completo A.M. Papini in italiano

Nata a Firenze il 2 febbraio 1959. Coniugata con due figlie: Giulia, Indja (Firenze, 9 maggio 1991) e Elena, Désirée (Firenze, 10 aprile 1996). Nazionalità: francese e italiana. Immatricolata all'Ambasciata di Francia a Roma, Via Giulia 251 (NUMIC 00300232) con protezione consolare della Francia. Lingue (parlate e scritte) lingue madri: italiano e francese. Inglese etedesco.

Indirizzo

Unità di Ricerca Interdipartimentale di Chimica e Biologia di Peptidi e Proteine - PeptLab c/o Dipartimento di Chimica "Ugo Schiff, Polo Scientifico dell'Università degli Studi di Firenze, Via della lastruccia 3-13, I-50019 Sesto Fiorentino. Tel. Studio +39-055-457-3561. Cell. +39-3478844146. e- mail: annamaria.papini@unifi.it. www.peptlab.unifi.it

FORMAZIONE E QUALIFICAZIONI ACCADEMICHE E PROFESSIONALI

1977: Maturità Scientifica. Liceo Scientifico Leonardo da Vinci, Firenze.

15/04/1983: Laurea in Chimica (indirizzo organico-biologico), Università degli Studi di Firenze. Titolo della tesi di laurea: “Funzionalizzazione regioselettiva di eteri e tioeteri ciclici: sintesi di derivati bifunzionali via composti organometallici del gruppo IVB” (Relatore: Prof. A. Ricci, Correlatore: Prof. F. De Sarlo).

5/09/1990. Titolo di Dottore di ricerca in Scienze Chimiche, Roma (Ministero della Pubblica Istruzione). Titolo della tesi: "Sintesi di peptidi e loro studio sotto il profilo chimico, bio-farmacologico  ed immunologico". Tutori Prof. L. Moroder, Max Planck Institute for Biochemistry, Martinsried (DE) e Prof. G. Rapi, Dip.to Chimica Organica, Università di Firenze(IT).

1984-1989: Dottorato di Ricerca internazionale in Scienze Chimiche: 1984-1985 Vincitrice di  Concorso del Ministero della Pubblica Istruzione per titoli ed esami, per l’attribuzione di novantasette borse di studio per il settore 1, Scienze Chimiche, per la frequenza di attività di specializzazione o dottorato di ricerca presso istituzioni estere di livello universitario, I Ciclo (G.U. 79, 22.3.83). Nono  posto della graduatoria dei vincitori. Progetto: "Molecular mechanisms of allergic contact dermatitis", Faculté de Médecine, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke  (Canada) (Prof. G. Dupuis). 1986-1989 Vincitrice di Concorso del Ministero della Pubblica Istruzione  per Dottorato di ricerca in Scienze Chimiche, III Ciclo. 1986-1987: Dipartimento di Chimica Organica, Università degli Studi di Firenze (Prof. G. Rapi). 1988-1989: Max Planck Institute for Biochemistry, Department of Peptide Chemistry, Martinsried (DE) (Prof. Dr. L. Moroder). Progetto: "Sintesi e attività biologica di peptidi della colecistochinina e di loro coniugati con proteine per studi di immunochimica". 1990-1991 (12 mesi): Post-doctoral fellow, Dipartimento di Dermatologia, Azienda ospedaliera universitaria, Università di Firenze. Supervisore Prof. M.D. E. Panconesi. Progetto: "Chemical aspects of hapten-carrier interaction in immune response of contactallergy".

1984: Abilitazione alla professione di chimico e iscritta all'Ordine dei Chimici della Toscana dal 1984 (N. d'ordine 1073).

Abilitazione Scientifica Nazionale a Professore Ordinario in Italia

11/12/2013-11/12/2022 e 06/09/2018-06/09/2029: Abilitazione Scientifica Nazionale per Professore di Prima Fascia, Settore Concorsuale 03/C1 Chimica Organica e SSD CHIM 06 – Chimica Organica.

Abilitazione a "Professeur des Universités francaises, CNU Section 32: Chimie organique, minérale et industrielle" del "Ministère de l'Education Nationale" in Francia (equivalente a professore ordinario in Italia).

2001-2004: n° qualification 01132111096 e 2005-2008: n° qualification 05132111096.

POSIZIONI RICOPERTE E RESPONSABILITA'

ATTIVITÀ PROFESSIONALE ACCADEMICA E DI TERZA MISSIONE PRESSO L'UNIVERSITA' DI FIRENZE

Dall'1/03/2020: Professore Ordinario di ruolo di prima fascia per il settore concorsuale 03/C1 (Chimica organica), SSD CHIM/06 (Chimica Organica) quale vincitrice di procedura selettiva ex art. 18, comma 1, Legge 240/2010 (approvazione atti 20/11/2019, dai quali risulta prima in graduatoria su 5 candidati).

1/11/2002-29/02/2020: Professore universitario di ruolo di seconda fascia confermato per  il  settore scientifico-disciplinare CHIM/06 presso la Facoltà di Scienze Matematiche Fisiche e Naturali (SMFN) dell'Università di Firenze. Afferente al Dipartimento di Chimica Organica "Ugo Schiff" confluito da gennaio 2010 nel Dipartimento di Chimica (valutazione comparativa per posti n. 1, per la Facoltà di SMFN dell’Università di Firenze, G.U. n. 29, 4a serie speciale, del 12/04/2002, risultata prima su 3 candidati).

1/11/2001-31/10/2002: Ricercatore universitario confermato per SSD CHIM/06 -  Chimica  organica, Facoltà di SMFN di Firenze, afferente al Dipartimento di Chimica Organica (Vincitrice di valutazione comparativa per un posto di ricercatore universitario confermato riservato a tecnici laureati per il SSD C05X Chimica Organica presso la Facoltà diSMFN).

31/12/1991-31/10/2001: Inquadrata nei profili della VIII qualifica funzionale, perché in possesso dei requisiti richiesti dalla legge 21/91 presso il Dipartimento di Chimica Organica “Ugo Schiff”, Università di Firenze.

1/01/1991-30/12/1991: Nominata VII qualifica funzionale tecnico scientifica e socio sanitaria  presso il Dipartimento di Chimica Organica “Ugo Schiff”, a seguito di pubblico concorso a n. 1 posto di collaboratore tecnico che prevedeva come requisito per l’ammissione il diploma di laurea in Chimica (G.U. n. 62-bis del 7/8/1990).

RESPONSABILITA' PRESSO LA SCUOLA DI SCIENZE, MATEMATICHE, FISICHE E NATURALI DELL'UNIVERSITA' DI FIRENZE

2025-2029: Membro eletto del Collegio della Scuola di SMFN, quale rappresentante del Dipartimento  di Chimica "Ugo Schiff” (secondomandato).

2022-2025: Nominata vice-presidente della Scuola di SMFN

Dal 2013: Delegata alle Relazioni Internazionali e responsabile del programma Erasmus+. OltreagestiretuttelemobilitàdeglistudentiErasmus+inentrataeuscitaperstudioetraineeship(ca.

300 studenti/anno dei CDS in Fisica, Chimica, Matematica, Informatica, Scienze Biologiche, Scienze Naturali, Scienze della Terra, Ottica, Biotecnologie, Beni Culturali), ha coordinato la stipula degli accordi per i doppi titoli di LM54 in Scienze Chimiche e in "Advanced Molecular Sciences" dell'Università di Firenze con: 1) Master en Quimica Avanzada dell'Università di Burgos (ES); 2) Master en Chimie dell'Université de Rouen Normandie (FR) per cui é stato ottenuto un finanziamento dall'Université franco-italienne per il 2022-2025 (30.000,00 Euro) per lo scambio di 4 studenti/anno; 3) Master in "Integrative Chemistry and Innovation"di ChimieParisTech, ENS e ESCPI Paris di PSL Université Paris; 4) Master in Chemistry della Hebrew University of Jerusalem (IL).

2021-2025: Membro eletto del Collegio della Scuola di SMFN, quale rappresentante del Dipartimento  di Chimica "Ugo Schiff”.

Dal 2018: Nominata membro del Comitato per la didattica nel CDS in Chimica.

Dal 2016: Delegata per i tirocini all'estero del CDS in Chimica.

Dal 2019: Delegata per i tirocini all'estero del CDS in "Advanced Molecular Sciences".

2010-2014: Rappresentante della Facoltà di SMFN nel Consiglio Direttivo del Centro Linguistico di Ateneo.

2012: Membro della Commissione per la Valutazione dei candidati dei TFA A059 (Tirocini Formativiattivi per insegnanti di Chimica delle ScuoleSuperiori).

2011: Rappresentante del Dipartimento di Chimica "Ugo Schiff" nel Polo di Innovazione per le Scienze della Vita.

Dal 2005: Responsabile del Programma Erasmus+ per il CDS in Chimica

2006-2016: Vice-presidente e delegata per la chimica nel Consiglio Direttivo di OpenLab, centro di servizi per l'educazione e la divulgazione scientifica.

PARTECIPAZIONE A COLLEGI DI CORSI DI DOTTORATO

2024-2027: Coordinatore eletto per il secondo mandato del Corso di dottorato in Scienze Chimiche dell'Università di Firenze (Curricula: CHIMICA e SCIENZA PER LA CONSERVAZIONE DEI BENI CULTURALI) - Ciclo 40.

2021-2024: Coordinatore eletto del Corso di dottorato in Scienze Chimiche dell'Università di Firenze (Curricula: CHIMICA e SCIENZA PER LA CONSERVAZIONE DEI BENI CULTURALI) - Cicli 35, 36, 37, 38

e 39. https://www.dottoratoscienzechimiche.unifi.it/index.html?newlang=eng

Dal 2010: Partecipa al Collegio dei docenti del Corso di Dottorato di ricerca in Scienze Chimiche dell'Università di Firenze.

Dal 2022: Partecipa al Collegio dei docenti del Corso di DOTTORATO NAZIONALE IN HERITAGE SCIENCE, Coordinatore nazionale Università degli Studi di ROMA "Sapienza" - Cicli 38 e39.

2006-2009: Partecipa al Collegio dei docenti del Corso di dottorato in DINAMICA NON LINEARE E SISTEMI COMPLESSI dell'Università di Firenze.

RESPONSABILITA' DI RICERCA E TERZA MISSIONE

1995-2001: Fonda ed é nominata responsabile del primo Laboratorio di Sintesi di Peptidi presso il Polo Biomedico, assegnato al Prof. G. Rapi del Dip.to di Chimica Organica, per le esigenze della ricerca della Cattedra di Chimica e Propedeutica Biochimica, Università di Firenze.

Dal 2004 ad oggi Fonda insieme a F. Lolli, P. Rovero, e M. Chelli e coordina l'Unità di Ricerca Interdipartimentale di Chimica e Biologia di Peptidi e Proteine (PeptLab) presso l’Università di Firenze, costituita dai Dip.ti di Chimica "Ugo Schiff" (DICUS) e di Neuroscienze, Area del Farmaco e Salute del Bambino (NEUROFARBA), che afferiscono rispettivamente alle Scuole di SMFN e di Scienze della Salute Umana.

ATTIVITA' DI COORDINAMENTO DELL'UNITA' DI RICERCA INTERDIPARTIMENTALE DI CHIMICA E BIOLOGIA DI PEPTIDI E PROTEINE - PeptLab - www.peptlab.unifi.it

PeptLab è una unità di ricerca interdipartimentale riconosciuta a livello internazionale per la sua infrastruttura per la risoluzione di problematiche di ricerca e trasferimento tecnologico verso chi ricerca know-how e skills nell'ambito degli amminoacidi, peptidi e proteine, loro sintesi, purificazione e caratterizzazione chimica, biologica ed immunochimica. La dimostrazione lampante è stata nell'essere riuscita ad attirare 1049 partecipanti da 45 paesi del mondo dai 5 continenti al 37th European/14th International Peptide Symposium che ha organizzato insieme a Paolo Rovero (NeuroFarba, Università di Firenze) dal 25 al 31 Agosto 2024 a Firenze, Palazzo dei Congressi (www.eps2024.com), inclusi tre workshop satelliti su tematiche di frontiera della scienza dei peptidi quali "Applications of computational AI/ML in peptide research with a roadmap to peptide drug and material development", "Embracing innovation and sustainability in peptide synthesis", "Navigating entrepreneurship and technology transfer in peptide discovery and development (supported in part by EUniWell, Project TTpep: Technology Transfer of Peptides for the Well-beingEconomy)".

PEPTLAB NELLE ATTIVITA' DI TRASFERIMENTO TECNOLOGICO

PeptLab  è costituito da una Unità di Sintesi, una Unità di Purificazione e Caratterizzazione, una Unità  di Produzione di Proteine, una Unità di Proteomica e una Unità di Immunochimica. Lavorano circa 20 giovani i cui salari sono finanziati esclusivamente da fondi di ricerca di PeptLab. La piattaforma tecnologica di PeptLab è stata fortemente finanziata grazie a contributi della Fondazione Ente Cassa di Risparmio di Firenze.

2020-2024: CASO DI STUDIO PEPTIDES4WELLNESS PER VQR ANVUR. I risultati portati avanti da PeptLab (c/o i Dipartimenti di Chimica e NeuroFarBa dell’Università di Firenze) nell’area scientifica SCIENZE CHIMICHE e riassunti nel caso studio “Peptides4Wellness” sono stati conferiti per la valutazione ANVUR nelle aree: TEMATICA 1: Trasferimento tecnologico (campi di azione 1: Iniziative di cross-innovation e cross-fertilization, collaborazioni Impresa-Università, 2: Valorizzazione proprietà intellettuale o industriale, 3: Imprenditorialità accademica); TEMATICA 3: Scienze della vita e salute (campi di azione 1: Prevenzione, promozione e tutela della salute pubblica, 2: Salute ambientale e sicurezza alimentare); TEMATICA 4 (campo azione 1: Transizione ecologica ed energetica, sostenibilità ambientale e climatica).

Dal 2003: EspiKem S.r.l.. Primo spin-off dell'Università di Firenze fondato nel 2003 da A.M. Papini. EspiKem opera in convenzione presso PeptLab con contratti di ricerca conto terzi annuali, gestiti amministrativamente dal DICUS.

2007-2014: Toscana Biomarkers S.r.l.. Start-up nata dall'"Approccio Chimico Inverso" messo a punto presso PeptLab e fondata da A.M. Papini per la ricerca e sviluppo di test diagnostico-prognostici per malattie mediate dal sistema immunitario, basati su peptidi modificati. Toscana Biomarkers ha commissionato nel periodo 2007-2014 a PeptLab attività di ricerca in outsourcing anche finalizzata a progetti finanziati dalla CE.

2016-2022: Apotech S.r.l.. Start-up fondata da A.M. Papini. Apotech si è occupata della commercializzazione di prodotti cosmeceutici basati su peptidi della Serpina A1 sviluppati da PeptLab in

collaborazione con EspiKem. Da luglio 2020 ha contribuito al trasferimento della tecnologia a RELIFE (gruppo Menarini), del prodotto cosmeceutico anti-aging DEFINISSE KP1 che è stato lanciato sul mercato il 23 Settembre 2023 (https://www.relife.ie/aesthetic-medicine/definisse-kp1/redensifying- cream/). Un nuovo analogo del peptide Serpina A1 (inibitore fisiologico della degradazione del collagene) è rivendicato in un brevetto internazionale depositato dall'Università di Firenze in collaborazione con EspiKem di cui A.M. Papini è uno degli inventori ed è attualmente in fasedi valorizzazione.

Dal 2016: Laboratorio MOD&LS (Molecular Diagnostics & Life Sciences). Responsabile  scientifico delle attività di ricerca e servizio del centro di competenza RISE B, finanziato dalla Regione Toscana (PAR FAS 2007-2013, P.I.R. 1.3, azione 1 infrastrutture per settori produttivi, Sesto F.no) e incubato presso l’Incubatore dell’Università di Firenze. Fornisce know-how e servizi alle imprese anche per la fornitura di antigeni sintetici per test diagnostici dell'autoimmunità, prodotti sviluppati e licenziati dalla startup da lei fondata Toscana Biomarkers (2007-2014), ad aziende nel settore della diagnostica  in vitro a livello internazionale (DIESSE, DIAMETRA,ecc.).

2017-2020: PeptFarm: Fondatore e coordinatore scientifico del Laboratorio congiunto PeptFarm "Università di Firenze – Impresa" (incubato presso MOD&LS) fondato tra PeptLab e Fabbrica Italiana Sintetici, F.I.S.,  S.p.a. (Vicenza, IT) per il trasferimento della tecnologia per la produzione su larga  scala in GMP di peptidi, principi attivi farmaceutici (si vedano doi: 10.1021/acs.oprd.0c00490 e doi: 10.1021/acs.oprd.1c00368).

PEPTLAB NELLE ATTIVITA' DI INTERNAZIONALIZZAZIONE

2024 A.M. Papini coordina le attività di PeptLab dell'Università di Firenze nel progetto EUniWell "Sustainable and green upscaling processes for peptide(-based) in vitro diagnostics and  cosmeceuticals", nell'ambito del Third round of selected projects in the Well-Being Research Incubator Programme, insieme all'University of Cologne (Prof. Ines Neundorf), Semmelweis University (Prof. Istvan Mandity), University of Birmingham (Dr. HelenHook).

Giugno 2023-Agosto 2024 PeptLab per l'Università di Firenze (Prof. A.M. Papini e Prof. P. Rovero) vince in collaborazione con la University of Cologne (coordinatore Prof. I. Neundorf), Semmelweis University (Prof. I. Mandity), University of Birmingham (Dr. H. Hook) la 5th EUniWell Seed Funding Call (SFC5) per l’implementazione del progetto TTPep - Peptides for Well-being (Technology Transfer of Peptides for the Well-being Economy) che ha lo scopo di promuovere ipeptidi educando le nuove generazioni in questo settore emergente di molecole naturali ad elevato impatto per la salute e il benessere. Specifici corsi di training, seminari e workshop permetteranno di sviluppare conoscenza nella scienza dei peptidi da valorizzare come prodotti diagnostici, farmaci, cosmeceutici anche in una prospettiva di economia circolare.

2009-2020 PeptLab è stato associato all'unità di ricerca Chimie Biologie (LCB), UMR-CNRS-8076 BioCIS - Biomolécules : Conception, Isolement, Synthèse della CY Cergy Paris Université / Université Paris Saclay / CNRS (sito di Neuville sur Oise, Cergy-Pontoise) presso cui A.M. Papini ha creato dal 2008 la Piattaforma PeptLab@UCP ora CY PeptLab, grazie alla Chaire d'Excellence 2009-  2014 attribuitale dall'Agence Nationale de la Recherche. A.M. Papini é stata Direttore della Piattafroma PeptLab@UCP dal 2013 al 2020.

PeptLab accoglie studenti da tutto il mondo che hanno interesse a formarsi nell'ambito della chimica, immunochimica e biologia di peptidi e proteine per applicazioni in ambito diagnostico, terapeutico, cosmeceutico, dei materiali mirati a processi di rigenerazione, di economia circolare, ecc.

PREMI E RICONOSCIMENTI SCIENTIFICI

2025: MEDAL OF THE POLISH CHEMICAL SOCIETY attribuita dalla Polish Chemical Society. La medaglia sarà attribuita il 22 settembre, 2025 presso la Wrocław University of Science and Technology (Poland) durante la cerimonia di apertura del Congresso annuale della Polish Chemical Society. Presenterà una plenary lecture il 24 settembre 2025.

Giugno 2025-Febbraio 2026: PREMIO EUNIWELL CHAMPION PEPTIDES4WELLNESS come senior academic "to take the leadership role in advancing EUniWell’s mission to foster well-being across universities and society. Through their expertise and vision, EUniWell Champions will contribute to developing the well-being focused future directions of the Alliance". L'attribuzione formale del titolo di Champion avverrà a Santiago de Compostela durante il 1st meeting of the Centre for Advanced Studies (CAS) Symposium: Innovation in Well-being for Sustainable Development Goals Achievement, presentando la Keynote lecture come UNIFI EUniWell Champion: “Peptides 4 WellBeing”.

2024:BARRYCOHENPRIZEFORMEDICINALCHEMISTRY/CHEMICALBIOLOGY attribuito dalla Israel Chemical Society. Il premio è stato attribuito il 18 luglio, 2024 alWeizmann Institute of Science, Rehovot, dopo la presentazione della keynote lecture: Titolo: From chemical immunology to medicinal chemistry: the power of peptides to elucidate the mystery of molecular mimicry.

2019:RITA LEVI MONTALCINI PRIZE 2018 per la cooperazione scientifica Italia-Israele per la ricerca “The chemical reverse approach to understand the molecular mechanisms ofautoimmune diseases: research project from bench to bedside to develop diagnostic assays”, Israeli Council for Higher Education.            http://www.unifimagazine.it/premio-la-cooperazione-scientifica-italia-israele-ad-anna-maria-papini/, https://ambtelaviv.esteri.it/ambasciata_telaviv/it/ambasciata/news/dall_ambasciata/2019/04/giornata- della-ricerca-italiana.html.

2009-2014: CHAIRE D'EXCELLENCE EDITION 2009, unica cattedra in Francia attribuita alla  Chimica su 16 totali attribuite alle diverse discipline e assegnata dall'Agence Nationale de la Recherche del Ministère de l’enseignement supérieure et de la recherche (FR) per il progetto: "PepKit. Développement de kits de détection de maladies autoimmunes basés sur des peptides" (ANR-09-CEXC- 013-01).

2008: LEONIDAS ZERVAS AWARD for outstanding contribution made to peptide chemistry, 30th European Peptide Symposium, Helsinki, Finland, 31/08/2008.

2008: 1st DIMITRIS THEODOROPOULOS MEMORIAL LECTURE AWARD for outstanding achievements in Peptide Sciences, 6th Hellenic Forum on Bioactive Peptides, 18/05/2008.

2006: BEST POSTER AWARD LUCIO SENATORE, XXII Congresso Nazionale della Società Chimica Italiana [V. Volkov, F. Nuti, Y.Takaoka, R. Chelli, A.M. Papini, and R. Righini. Structure and bonding of water molecules in the polar region of phospholipid membrane investigated by two-dimensional IR spectroscopy and MD computer simulation. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006, Abstract FIS-P-135], attributed to the work performed with the Postdoc student F. Nuti and the coworker R. Chelli.

2005: BERT SCHRAM PRICE, HONORABLE MENTION, 19th American Peptide Symposium, San Diego, California, USA [B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOGED with the synthetic putative autoantigen CSF114(Glc) and [N31(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. 19th American Peptide Symposium (San Diego, CA, USA), June 18-24, 2005, LY 03, Abstract p. 484], attributed to the work performed with the PhD student B.Mulinacci.

2005: BEST POSTER AWARD GLYCO XVIII, XVIII International Symposium on Glycoconjugates, Florence, Italy [F. Nuti, I. Paolini, B.Mulinacci, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Sugar-scan of CSF114(Glc) for autoantibody recognition in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Firenze, September 4-9, 2005, Abstract P057, Glycoconjugate J., 2005, 22(4–6), 254], attributed to the work performed with the PhD student F. Nuti.

1999: BRUCE W. ERICKSON AWARD for outstanding achievement in peptide sciences, 16th American Peptide Symposium, Minneapolis, Minnesota, USA [E. Nardi, S. Mazzucco, S. Matà, M.Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli] attributed to the PhD student E. Nardi.

ATTIVITÀ PROFESSIONALE ACCADEMICA DI DIDATTICA E RICERCA E DI TRASFERIMENTO TECNOLOGICO A LIVELLO INTERNAZIONALE

2009-2014: Vincitrice della "Chaire d'Excellence" Edition 2009 dell'Agence Nationale de la Recherche del Ministère de l’enseignement supérieure et de la recherche (FR), unica attribuita alla chimica su 16 vincitori. Assegnati 989.200,00 Euro per l'attività quinquennale per il progetto: "PepKit: Développement de kits de détection de maladies autoimmunes basés sur des peptides".

2013-2020: Fonda e dirige la Piattaforma italo-francese PeptLab dell’Università di Firenze e di CY  Cergy Paris Université (Cergy-Pontoise,FR).

2019: Fonda la prima piattaforma per sintesi su larga scala di peptidi PeptLab@UCP presso CY Cergy Paris Université (Neuville sur-Oise, FR), installando in Europa il primo sintetizzatore assistito da microonde Liberty Pro (CEM, Charlotteville, NC, USA).

2001: Classificata al primo posto della graduatoria di un concorso per titoli ed esami (JO n50 28/02/2001) per il posto di Professore 32 PR 0788 presso l’Università di Lyon-1 (FR), section 32, Chimica Organica, Minerale e Industriale, profilo Molecole bioattive, Chimica biomimetica. Rinuncia per  il progetto Sclerosi Multipla, sviluppo di un kit diagnostico da svolgersi presso il Polo Scientifico e Tecnologico dell'Università di Firenze.

ATTIVITA' DIDATTICA IN ISTITUZIONI ESTERE E VISITING PROFESSOR

2023-2025: ISI Florence - INTERNATIONAL STUDIES FLORENCE - CHEM 212 – Organic Chemistry II

(3 CREDITS), Discipline: Chemistry, STEM. Spring semester. Taught  in: English. Instructors: Anna  Maria Papini Ph.D. (4 Guest lectures) and Claudia BelloPh.D.

2008 (1 mese): Professore invitato presso l'Université de Bourgogne, Dijon (FR). 2008 (1 mese ): Professore invitato presso l'Université de Cergy-Pontoise, Neuville sur Oise (FR). 2005 (1 mese): Professore invitato presso l'Université de Bourgogne, Dijon (FR). 1999 (1 mese): Professore a tempo determinato (PAST 8035), Département de Chimie U.F.R. Sciences et Techniques, Neuville sur Oise, Université de Cergy-Pontoise (FR). 1997-1998 (6 mesi): Professore a tempo determinato (PAST 8035), Département de Chimie U.F.R. Sciences et Techniques, Neuville sur Oise, Université de Cergy- Pontoise (FR).

ERASMUS+ TEACHING MOBILITY

Febbraio 2020: Université de Rouen (8h). Gennaio 2019: Faculty of Chemistry of the University of Wroclaw (PL). Level: Bachelor, Master and PhD in Chemistry (13h). Gennaio 2018: Faculty of Chemistry of the University of Wroclaw (PL). Level: Bachelor, Master and PhD in Chemistry (10 h). Giugno 2016: Erasmus Teaching Mobility at the Faculty of Chemistry, University of Wroclaw (PL) – Level: PhD in Chemistry (Call 2015 – KA1, 8h). Maggio 2016: Faculty of Chemistry, University of Wroclaw (PL) – Level: Master in Chemistry – LLP Erasmus Teaching Mobility Call 2015 – KA1, 8h). Settembre 2012: Università di Patrasso (GR) - Level: Master in Medicinal Chemistry – LLP Erasmus Teaching Mobility (AF N° 2011-1-IT2-ERA02-25889, 5h). Settembre 2010: Abant Izzet Baysal University, Faculty of Arts & Sciences, Bolu (TR) - Level: Master e PhD in Chemistry - LLP Erasmus TeachingMobility(AFN°2009-1-IT2-ERA02-09056,5h).Settembre2010:UniversityofBalikesir(TR)

- Level: Master in Chemistry - LLP Erasmus Teaching Mobility (AF N° 2009-1-IT2-ERA02-09056, 5h). Luglio 2010: Università di Patrasso (GR) - Level: Master in Medicinal Chemistry – LLP Erasmus Teaching Mobility (AF N° 2009-1-IT2-ERA02-09056, 5h). Ottobre 2010: University of Gdansk (PL) - Level: Master in Chemistry - LLP Erasmus Teaching Mobility (AF N° 2009-1-IT2-ERA02-09056, 5h). Dicembre 2004: Université Henry Poincaré Nancy 1, Faculté des Sciences et Techniques, Nancy (FR) - Level: D.E.A. Microbiologie-Enzymologie-Nutrition (Aspects Moléculaires et Cellulaires), Magistére Microbiologie-Enzymologie (3éme année). Module Biophysique et Biologie Structurale(8h).

ATTIVITA’ DIDATTICA PRESSO L’UFR SCIENCES ET TECHNIQUES, UNIVERSITE DE CERGY- PONTOISE (FR)

2015-2020: 132h/anno. Semester 1, Course Master 1: Bioorganic Chemistry (20h: 10h CM + 10h   TD), Course Master 2 Molecules for health: Peptides and Proteins (15h CM) and Immunochemistry (6h CM). Semester 2, Course Master 1 – option biomolecules: Amino acids and peptides (20h: 10h CM + 10h TD). Practical tutorials (Travaux Pratiques) Organic Chemistry(35h).

2009-2014: 60h/anno Semester 1: Bioorganic Chemistry (20h: 10h CM + 10h TD). Travaux Pratiques Chimie organique (35h).

CREAZIONE E RESPONSABILITA' DI ACCORDI INTERNAZIONALI CON ISTITUZIONI EUROPEE E EXTA-EUROPEE

DOPPI TITOLI

2020-2025 e 2026-2030: Doppio titolo tra la LM54 Scienze Chimiche dell'Università di Firenze e il Diplome de Master en Chimie dell'Université de Rouen Normandie. Vincitrice di un finanziamento dell'Université Franco-Italienne por la mobilità di studenti in entrata e in uscita nel quinquennio 2020- 2025.

2021-2026: Doppio titolo tra la LM54 in Scienze Chimiche e Advanced Molecular Sciences  dell'Università di Firenze e il Diplome de Master in Chemistry dell'Université Paris Sciences et Lettres, Ecole Nationale Supérieure de Chimie de Paris, Ecole normale supérieure, Ecole Supérieure de Physique et de Chimie de la Ville de Paris, Chimie ParisTech(France).

2023-2027: Doppio titolo tra la LM54 Scienze Chimiche e Advanced Molecular Sciences dell'Università  di Firenze e il Master in Chemistry della Hebrew University of Jerusalem.

2016-2020: Doppio titolo tra la LM54 Scienze Chimiche e il Master en Quimica Avanzada dell'Universidad de Burgos (Spain).

ACCORDI DI COLLABORAZIONE CULTURALE E SCIENTIFICA

2025-2029 Accordo tra il Dipartimento di Chimica dell'Università di Firenze e il Department of Chemistry dell'Université de Montreal (Prof. W.D. Lubell).

Dal 2019 e rinnovato per 2025-2029: Accordo tra il Dipartimento di Chimica dell'Università di Firenze e Osaka Municipality University, Faculty of Chemistry (Prof. I. Fujii e Prof. I. Nakase).

2019-2027: Accordo tra il Dipartimento di Chimica dell'Università di Firenze e l'Institute of Chemistry della University of Wroclaw (Prof. P. Stefanowicz).

2019-2027: Accordo tra il Dipartimento di Chimica dell'Università di Firenze e la Faculty of Chemistry della Wroclaw University of Science and Technology (Prof. R. Latajka).

ATTIVITA' SCIENTIFICA ALL'ESTERO

2025-2026 - I semestre: EUNIWELL CHAMPION "to advance EUniWell’s mission to foster well-being across universities and society and contribute to developing the well-being focused future directions of the Alliance". 7 MOBILITA'- MOBILITY 1. October 2025 (7 days): University of Cologne (EUniWell alliance). Host: Prof. Dr. Ines NEUNDORF. MOBILITY 2. November 2025 (5 days): University of Bonn (NeurotechEU alliance). Host: Prof. Dr. Diana IMHOF. MOBILITY 3. December 2025 (7 days): Pôle Universitaire d'Innovation, Nantes Université (EUniWell alliance). Host : Dr. Céline BRESSOLLETTE- BODIN, Médecin-biologiste, Maître de conférence praticien hospitalier. MOBILITY 4. January 2026 (5 days): Institute of Chemistry for Life and Health Sciences, Chimie ParisTech (alliance EELISA). Host: Prof. Carlo ADAMO. MOBILITY 5. February 2026 (5 days): University of Santiago deCompostela (EUniWell alliance). Host: Prof. Fernandez Maria Josefa ALONSO. MOBILITY 6. March 2026 (7 days): Semmelweis University, Research Centre for Natural Sciences, Institute of Materials and Environmental Chemistry (EUniWell alliance). Host: Prof. Dr. Istvan MANDITY. VIRTUAL MOBILITY 7: October 2025- March 2026 (6 days): University of Rijeka, Croatia (YUFE alliance). Host: Associate Professor Daniela KALAFATOVICH, PhD.

2019-2020: Visiting Research Professor presso Institute of Chemistry della Hebrew Universityof Jerusalem, Faculty of Medicine, Bar-Ilan University e Weizmann Institute of Science per la cooperazione scientifica Italia-Israele per la ricerca “The role of bacterial glycoproteins in the animal model of  multiple sclerosis" finanziato da Israeli Council for HigherEducation.

2009-2020: Direttore delle attività scientifiche della Piattaforma PeptLab@UCP, CY Cergy Paris Université, Neuville sur Oise (FR).

1999 (2 mesi): Visiting researcher DAAD (Deutscher Akademischer Austauschdienst), Medizinisch Naturwissenschaftlichens Forschungs Zentrum, University of Tuebingen (DE). Progetto: T-cell response and peptidase susceptibility of lipopeptide epitopes.

1999 (1 mese): Visiting researcher, Département de Chimie, Laboratoire de Synthèse Organique Sélective et Chimie Organométallique (SOSCO), Universitè de Cergy-Pontoise (FR). Progetto: Synthesis of unnatural amino acids protected for solid-phase peptide synthesis.

1998 (6 mesi): Visiting fellow, Département de Chimie, Laboratoire de Synthèse Organique Sélective et Chimie Organométallique (SOSCO), Universitè de Cergy-Pontoise (FR).Progetto: Synthesis of unnatural amino acids protected for solid-phase peptidesynthesis.

ATTIVITA' SCIENTIFICA PRESSO ISTITUZIONI DI RICERCA

2017-2020: Associata all'Istituto CNR di Cristallografia.

ATTIVITA' DI TERZA MISSIONE: TRASFERIMENTO TECNOLOGICO

2003: Fonda insieme a F. Lolli, P.  Rovero e M. Chelli EspiKem Srl il primo spin-off dell'Università  di Firenze, Contract Research Organisation specializzata in sintesi, purificazione e caratterizzazione di peptidi e peptidomimetici per ricerca su commissione, collaborando in convenzione conto terzi con PeptLab dell'Università di Firenze.

2007-2014: Fonda insieme a F. Lolli, P. Migliorini, M. Chelli e P. Rovero Toscana Biomarkers Srl partecipando alla societa' con una quota del 10% insieme a SICI, Biofund e Toscana Venture come soci di maggioranza. E' stata Presidente del Comitato Scientifico. Toscana Biomarkers è stata bioincubata  nel parco scientifico di Siena dalla Fondazione Toscana Life Sciences in Via Torre Fiorentina. Dipendenti di Toscana Biomarkers sono stati cinque giovani ricercatori e due borsisti della Provincia di Siena. La missione di Toscana Biomarkers è stata la ricerca e lo sviluppo di nuove molecole peptidiche come  sonde antigeniche di patologie autoimmuni per lo sviluppo di test diagnostici innovativi e laloro applicazione in piattaforme analitiche per uso clinico-diagnostico. La proprietà intellettuale di Toscana Biomarkers é stata licenziata a produttori europei di IVD: Diametra (Milano, IT), Theradiag (Paris, FR).

PREMI E RICONOSCIMENTI PER ATTIVITA' DI TRASFERIMENTO TECNOLOGICO

2009: PREMIO VESPUCCI VI Edizione Award for the Start Up section and Special Mention of the Jury attributed to Toscana Biomarkers. "The mention is conferred for the remarkable development perspectives of the company, which is devoted to the research and production of novel methods and assays for the diagnosis of autoimmune diseases as multiple sclerosis and rheumatoid arthritis."

2008: FROST & SULLIVAN EXCELLENCE IN RESEARCH AWARD IN THE EUROPEAN AUTOIMMUNE DISEASE DIAGNOSTICS MARKET presented to Toscana Biomarkers, London (UK) March 2009.

2006 START CUP 2006 per il business plan di Toscana Biomarkers Srl.

2004:PREMIO VESPUCCI RICERCA INNOVAZIONE ETICA IN TOSCANA per la sezione Brevetti, assegnato ad A.M. Papini per il brevetto “Preparation of glycopeptides for use in the diagnosis or therapeutic  treatment  of  multiple  sclerosis”  [Inventors:  A.M.  Papini,  P.   Rovero,  M.  Chelli,  F.Lolli. Applicant: University of Florence, Italy. PCT International Application (2003) WO 03000733 A2. Priority Data FI2001A000114 del 22.06.2001 IT].

ORGANIZZAZIONE DI CONGRESSI SCIENTIFICI INTERNAZIONALI

2024: Chairperson insieme al Prof. P. Rovero del 14th International/37th European Peptide Symposium (https://eps2024.com/) che è stato organizzato a Firenze (IT) presso il Palazzo dei Congressi, 25-31/08/2024 (1049 partecipanti da 45 paesi del mondo e 5 continenti) (https://eps2024.com/).

2019: Chairperson della “Giornata scientifica della Società Italiana Peptidi dedicata ai Soci Giovani, Premio scientifico Vittorio Erspamer. September 21, 2019, Polo Didattico Morgagni, University of Florence, Viale Morgagni 44, Firenze (IT). 2019: Chairperson con Fernando Albericio dell'International Oligonucleotides and Peptides Conference, Track Peptides, Ramada Plaza Hotel, Milano (IT), September 17-18, 2019. 2019: Chairperson della Session III: Peptide Nutraceutics and Cosmeceutics and Session IV: Peptide Engineering and Smart Materials, CIS 2019 - Chemistry meets Industry  andSociety, Società Chimica Italiana, WS3 – Smart Peptide Chemistry for next generation industry in a sustainable society, Grand Hotel Salerno, Salerno (IT), August 28-30, 2019. 2018: Chairperson del 2nd Italian Peptide Society Meeting, Attribuzione del Premio Ernesto Scoffone 2018, Napoli (IT), 5-6 June 2018. 2017: Chairperson della Giornata Scientifica della Società Italiana Peptidi dedicata ai soci giovani con attribuzione del Premio Scientifico Vittorio Erspamer – Emerging Peptide Science from Italy, Firenze  (IT), Plesso Didattico Università di Firenze, Viale Morgagni 40-44, 23 Settembre 2017. 2016: Chairperson della Gordon Research Conference 2016 "The peptides, Chemistry & Biology of" insieme a Phil Dawson (The Scripps Research Institute, Departments of Cell Biology and Chemistry, La Jolla, CA), Ventura, CA, 21-26 Febbraio 2016 (https://www.grc.org/programs.aspx?id=11886).  2016: Chairperson del 1st Mass Spectrometry Peptide Day, Convento di Sant’Apollonia, Firenze, 10-12 Febbraio 2016 (http://www.spettrometriadimassa.it/Congressi/1MS-PeptideDay/). 2014: Chairperson dell’International Symposium Peptides in Paris PIPS 2014 e Training Course 5-10 Ottobre 2014. Co- editor del numero speciale su Biopolymers Peptide Science insieme a S. Lavielle (UPMC, Parigi) e W. Lubell (Université de Montreal, Canada). 2014: Responsabile del semestre tematico Peptides  &  Proteins Molecules of Life. Université de Cergy Pontoise (FR), evento finale della Chaire d’Excellence 2009-2014. 2014: Co-Chair della Gordon Research Conference 2014 "The peptides, Chemistry& Biology of", Ventura, CA, 23-28 Febbraio 2014  (https://www.grc.org/programs.aspx?id=11885).  2011: Chair del simposio "Peptides and proteins in the new millennium" organizzato in onore del Dottorato Honoris Causa conferito dall'Università di Cergy-Pontoise al Prof. L. Moroder a Neuville-sur- Oise (FR), 5-6 Ottobre, 2011. Ospite d'onore il premio Nobel per la chimica 1988 Robert Huber. In quell'occasione AM Papini ha presentato la "Laudatio" alla Carriera Scientifica di Luis Moroder. 2011: Chairperson del Simposio “Microwave-Assisted Organic Peptide Synthesis” (MAOPS2), Chiostro del Maglio, Firenze, 26-28 Aprile 2011. 2010: 1st Italy Australia Peptide Symposium on Biomolecules for Diagnostics & Therapeutics, Satellite del 31st European Peptide Symposium, Monash University, sede di Prato (IT), 10-12 Settembre 2010. 2007: EUROCOMBI4, 1st International Symposium on  Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials, Chiostro del Maglio, Firenze (IT), 15-18 Luglio 2007. 2006: International Training Course on Mass Spectrometry & High Performance Liquid Chromatography of Proteins (sponsorizzato dall'UNESCO e organizzato in collaborazione con il Prof. V. Schettino), Polo Scientifico dell'Università di Firenze, 1-12 Maggio 2006. 2003: 1st Practical Training Course: Innovative Combinatorial Approaches and Technologies, European Society of Combinatorial Sciences, Polo Scientifico dell'Università di Firenze, 9-11 Aprile 2003.

MEMBRO DEL COMITATO SCIENTIFICO DI CONGRESSI INTERNAZIONALI

2022: Membro del Scientific Advisory Board del 12th International Peptide Symposium/36th European Peptide Symposium, Sitges (ES) August 28-September 2, 2020 posticipato a August 28-September 2, 2022. 2020: Membro della Scientific Committee del 3rd Meeting della Italian Peptide Society,  December 12, 2020 (Webinar, Rome, IT). 2018: Membro della Scientific Committee del 16th Naples Workshop on Bioactive Peptides, Naples (IT) June 7-9, 2018. 2017-2019: Membro del Comitato Consultivo dell’American Peptide Symposium 2019, Monterey, CA, USA, 22-27 Giugno 2019. 2017- 2018: Membro del Comitato Organizzatore della European Chemistry Conference, Roma (IT) ,11-13 Giugno 2018. 2016: Membro del Comitato Scientifico del 34th European Peptide Symposium, Leipzig (DE). 2014: Membro del Comitato Scientifico del 33rd European Peptide Symposium, Sofia (BG).  2010: Membro del Comitato Scientifico del 31st European Peptide Symposium, Copenhagen (DA). 2009: Membro del Comitato Scientifico di SCS-09 2nd International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials, Bejing (Cina). 2001, 2002 e 2004: Membro del Comitato Scientifico del 2nd, 3rd e 5th Medicinal Chemistry Conference: Drug  discoveryand Design, University of Patras (GR).

FINANZIAMENTI DI PROGETTI DI RICERCA SU BANDI COMPETITIVI

2023-2026: Responsabile per UNIFI del Bando per la Ricerca Finalizzata anno 2021 “Ministero della Salute”, Progetto RF-2021-12374177. Titolo: “Persistence and magnitude of adaptive immune response to anti-SARS-CoV-2 vaccine, including assessment of cross reaction to virus variants, in  healthy children and in immunocompromised paediatric and adult patients: implication for  vaccinationstrategy”. Total funding €450.000,00: National PI F. Annunziato, Regione Toscana, AOU Careggi/SOD Centro Diagnostico di Citofluorimetria e Immunoterapia (Enrolment of immunocompromised adult patients and flow cytometric analysis of spike specific B and T cells of all patients of the project); Coordinatore OU3 per DICUS/PeptLab@UNIFI, University of Florence: A.M. Papini (Synthesis  ofpeptides of SARS-CoV-2 spike protein, both wild type and mutated); Coordinator OU2 for AOU Meyer, Dipartimento Specialistico Interdisciplinare: M. Resti (Enrolment of paediatric patients, both healthy  and immunocompromised ones, and quantification of SARS-CoV-2 specific Ig serumlevels).

2022-2025: Principal Investigator del progetto PNRR THE - TUSCANY HEALTH ECOSYSTEM (CUP B83C22003920001). Titolo: Development of diagnostic technologies based on synthetic modified peptide ("Synthetic Antigenic Probes, SAPs) to detect and characterize auto-antibodies as biomarkers   of immune responses. € 61.000,00 (PhD fellowship) + 36.000,00(materiali).

2020-2026: Responsabile per UNIFI del progetto LIFE18 ENV/IT/000460 “Life MILCH”: “Mother and Infant dyads: Lowering the impact of endocrine disrupting Chemicals in milk for a Healthy Life” (Totale per UNIFI € 711.028). 2021-2022: Responsabile Unità del progetto “Regione Toscana POR FESR 2014-2020” R&D of SMEs. ECO-SMART DEGREASING SYSTEM 4.0. Total cost of the project € 1.497.849,55 (UNIFI € 204.700,00). 2017-2019: Responsabile Unità del progetto “Regione Toscana POR CReO FESR 2014-2020”. EcoReLabel: Ecological removable and recyclable labels. € 303.000,00. 2011-2013: Responsabile Unità del progetto "Regione Toscana PAR FAS 2009 Linea di Azione 1.1.a.3" Progetto S.I.C.A.M.O.R.: Sviluppo di Indagini Chimiche Applicate al Mantenimento delle Opere e al Restauro. € 192.000,00. 2010-2012: Responsabile Unità del progetto “Regione Toscana POR CReO FESR 2007-2013”. Progetto MARK: Identification of diagnostic biomarkers of autoimmune diseases. € 450.000,00. 2005-2011: “Fondazione Cassa di Risparmio di Firenze”. Progetto: Molecular characterisation of peptide-protein interaction in autoimmune diseases. € 1.500.000 per PeptLab, Università di Firenze. 2005-2007: Coordinatore del progetto FIRB Internazionalizzazione -Italian Ministry of University & Research and Harvard Medical School (36 mesi). Progetto: Studio del ruolo  degli zuccheri nella eziologia della sclerosi multipla. € 350.000,00. 2002-2004, 2005-2007, 2008- 2010: Progetti PRIN-Italian Ministry of University & Research. Progetti: 1) Responsabile  unità:  Sviluppo e validazione di nuovi approcci terapeutici immuno-mediati per malattie demielinizzanti autoimmuni del sistema nervoso centrale; rilevanza per la sclerosi multipla (24 mesi); 2) Coordinatore Nazionale: Progettazione, sintesi e caratterizzazione immunologica di nuovi glicopeptidi mimetici di autoantigeni mielinici per lo studio dei meccanismi molecolari della sclerosi multipla e per lo sviluppo di strumenti diagnostici innovativi (24 mesi); 3) Coordinatore Nazionale: Progettazione, sintesi e caratterizzazione immunologica di peptidi modificati per la diagnosi ed il "follow-up" di malattie autoimmuni (24 mesi); Totali: €700.000,00.

2009-2014: “Chaire d’Excellence” Edition 2009 Categoria Sénior longue durée (ANR-09-CEXC-013- 01). PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases. € 999.998,00 for the PeptLab@UCP platform at Université Cergy-Pontoise (France). 2018: Région Ile de France, funding dedicated to launch the large-scale facility KgPeptLab@UCP at Université Paris-Seine, Neuville site, Cergy Pontoise (France). € 800.000,00. 2016-2018: Lauréate MRSEI-ANR Edition 2015, EU Project REDIPOC to organize and submit a FET-OPEN project for a Reliable Diagnostic Point Of Care Network. € 20.000,00.

2013-2016:  PhD grant by ANRT Thèse CIFRE in cooperation with REGULAXIS. € 90.000. 2015-2018: BIRAC, Indo-French Challenge-oriented Call for proposals 2014. “AMIR-PepKit IVD, R&D  of a peptide-based-diagnostic kit for an early detection of a fatal immune response in acute myocardial infarction patients”. € 50.000,00. 2011-2013: Responsabile Unità del progetto finanziato dalla Fondation Pierre-Gilles de Gennes pour la recherche (18 mesi). Projet n° 40, «Immune-mediated diseases: Glycopeptidomic-based diagnostics to follow up disease activity» in collaborazione con la   Prof. S. Lavielle, UPMC-ENS Paris - due postdoctoral fellowship, 2x18 months e 90.000,00 Euro per materiali. 2017-2020: Responsabile Unità del progetto dell'"Université franco-italienne".  Finanziamento di una posizione di dottorato di ricerca in cotutela tra la scuola di dottorato in Scienze Chimiche dell’Università di Firenze e l’Ecole Normale Supérieure di Parigi (Francia) Dottorando: A. Mazzoleni. Tutori: Prof. A.M. Papini e Dr. J.M. Mallet. 2007: Responsabile Unità del "Programme Action Integrées Galilée n°14418SL, Université Franco-Italienne" (12 mesi). University of Florence (PeptLab)   & Université de Cergy-Pontoise/Lab. SOSCO - Progetto Synthèse d'acides aminés glycosyléspour l'obtention de glycopeptides pour le diagnostic et le pronostic de la sclérose en plaques. Euro 4.000,00 per  scambio  di  ricercatori.  2006:  Responsabile  Unità  del  "Programme  Action  Integrées  Galilée N°11686QA, Université Franco-Italienne" (12 mesi). University of Florence (PeptLab) & Université de Dijon (CNRS, UMR 5188) - Progetto: Métallopeptides électrodétectables appliqués au diagnostic et à la thérapie des pathologies autoimmunes. Euro 4.000,00 per scambio di ricercatori). 2001: Coordinatore Nazionale del progetto finanziato dalla Fondazione Lieselotte und Dr. Karl Otto Winkler (Germania) (12 mesi). Progetto: Sintesi dei metaboliti del (2-etilesil)ftalato (DEHP) e del dibutilftalato (DBP). Finanziamento: Euro 4.906,00. 1998-2000: Programma Vigoni. Partners Dr. Anna Maria Papini, Dipartimento di Chimica Organica “Ugo Schiff”, Università degli Studi di Firenze; Prof. Dr. Dieter Mecke, Institute of Physiological Chemistry e Dr. Hubert Kalbacher, MNF, Universität Tübingen (Germany). “Studio del ruolo di peptidi e glicopeptidi della glicoproteina oligodentrocitica della mielina come nuovi antigeni in neuropatologie nell’uomo”. 1996-1999: Coordinatore Nazionale del progetto Istituto Superiore di Sanità - Ministero della Sanità - Progetto Sclerosi Multipla (36 mesi). Progetto di Ricerca: Caratterizzazione della risposta linfocitaria verso peptidi e lipopeptidi della proteina basica della mielina umana nella sclerosi multipla. Finanziamento: £ 155.000.000.

FINANZIAMENTI DI PROGETTI DI RICERCA E SVILUPPO E DOTTORATI DI INTERESSE INDUSTRIALE

Dal 1991: Fin dall'inizio del suo percorso professionale A.M. Papini si é occupata attivamente di trasferimento tecnologico e valorizzazione dei risultati della ricerca, come anche dimostrato dagli 11 brevetti di cui é coinventrice. Inoltre, a conferma dell'interesse e del suo forte coinvolgimento ha stipulato convenzioni di ricerca a livello nazionale e internazionale con aziende private quali F.I.S. Fabbrica Italiana Sintetici S.r.l. (2017-2020 Laboratorio congiunto PeptFarm), IMMCO Diagnostics Buffalo, Fresenius Cabi, Merck-Serono, Menarini S.p.A., ma anche con lo spin-off EspiKem (IP mirata a biopeptidi d’interesse cosmeceutico) e la start-up Toscana Biomarkers (IP mirata a test diagnostici per l’autoimmunità), che ha contribuito a fondare, oltre che con istituzioni di ricerca miste pubblico/privato quali l'Istituto Europeo di Oncologia e la Fondazione Bracco per un importo complessivo superiore ai 4.500.000,00 Euro.

Le tematiche sono state sempre mirate alla sintesi di peptidi e peptidi modificati anche su larga scala con strategie innovative per la produzione di ingredienti attivi come farmaci, peptidi costretti, glicopeptidi ecc. per studi di immunochimica, farmacologia, ecc., per la caratterizzazione di interazioni peptide-recettori, per lo sviluppo di test diagnostici per le malattie autoimmuni, per la messa a punto di processi di sintesi sostenibile di peptidi,ecc.

Dal 2021: E' tutore o cotutore di dottorati d’interesse industriale in Scienze Chimiche XXXVII CICLO cofinanziati su tematiche PON Ricerca e Innovazione 2014-2020 (D.M 1061/2021) da SPIN-PET S.r.l. Progetto: Sviluppo di materiali macromolecolari e reticolati a base proteica/peptidica a partire da fonti vegetali e da Gyros Protein Technologies AB Progetto: “Development of green technologies for the automated synthesis of peptide active ingredients”, per il XXXVIII CICLO del dottorato cofinanziato nel contesto del DM 352/2022 da FISCHER ANALYTICS GmbH Progetto: “Characterization of peptidome related to aberrant immune responses by innovative liquid chromatographic-mass spectrometric technologies”, per il XXXIX CICLO del dottorato cofinanziato dal PNRR - Tuscan Health Ecosystem,  Spoke 6, Precision Medicine and personalized healthcare.

PARTECIPAZIONE A BOARD, COMITATI DI VALUTAZIONE E COMMISSIONI

ATTIVITÀ DI VALUTATORE DI PROGETTI DI RICERCA E DI UNIVERSITA' e CENTRI DI RICERCA A LIVELLOINTERNAZIONALE

COMUNITA' EUROPEA (Evaluator EX2006A195962)

ERCEA - European Research Council Evaluation Agency

2012-2019: nominata dall'ERCEA a far parte quale Membro Esperto del Comitato per la Valutazione  dei progetti “Advanced Grant” presentati al Panel PE5 "Synthetic Chemistry and Materials"(2 riunioni/anno – 8 riunioni totali ogni 2 anni a Bruxelles (BE), valutazione di circa 100 progetti/anno per l’attribuzione di circa 5 milioni Euro/anno). ERC-2018-AdG PE5 PANEL EVALUATOR Step 2(Brussels, BE, 30/01-01/02/2019) e Step 1 (Brussels, BE, 20-22/11/2018). ERC-2017-AdGPE5 PANEL EVALUATOR 1 Step (28-30/11/2017). ERC-2016-AdG PE5 PANEL EVALUATOR Step 2 (Brussels,BE,23-25/01/2017)eStep1(Brussels,BE,14-16/11/2016).ERC-2014-AdG PE5 PANEL EVALUATOR Step 2 (Brussels, BE, 16-18/03/2015) e Step 1 (Brussels, BE, 12-14/01/2015). ERC- 2012-AdG PE5 PANEL EVALUATOR Step 1 e 2 (Brussels, BE).

REA - European Research Executive Agency

2018-2024: Evaluator, Briefing & Rapporteur of Individual Fellowships per Marie Curie Sklodowska- Curie Actions, b>REA HE-MSCA-PF-2024 (03/10/2024-02/12/2024), REA HE-MSCA-PF-2023 (1/10/2023-09/12/2023), REA HE-MSCA-PF-2022 (1/10/2022-09/12/2022) e REA HE-MSCA-PF- 2021 (18/11/2021-11/02/2022). 2020: H2020-MSCA-IF-2020 (2/10/2020-4/12/2020). 2019: H2020-MSCA-IF-2019 (7/10/2019-6/12/2019), 2018: H2020-MSCA-IF-2018 (25/09/2018- 15/11/2018).

Maggio 2025: HORIZON-JU-GH-EDCTP3-2025-01-02-Malaria - Crossreader di 7 progetti, 2024: HORIZON-JU-GH-EDCTP3-2024-01-02-Malaria - Evaluator e crossreader (Maggio 2024 e 14/10/2024- 08/11/2024.

Marzo-Giugno 2024: HORIZON-WIDERA-2023-TALENTS-01 (ERA Chairs 24) - Evaluators e Rapporteurs. Valutazione di 3 progetti

OTTOBRE 2023-DICEMBRE 2024: HORIZON-HLTH-2024-DISEASE-03-14 two stage - 1st Stage, Tackling high-burden for patients, under-researched medical conditions. Valutazione di 7 progetti.

NOVEMBRE 2023-GENNAIO 2024: HORIZON-WIDERA-2023-ACCESS-02, Expert e Cross-reader di 9 progetti.

NOVEMBRE 2023-MARZO 2024: EISMEA-EIC PATHFINDER CHALLENGES 2023, Rapporteur e cross-reader di 6 progetti.

JUNE-JULY 2023: EIC TRANSITION PROJECT Expert for the first review of the project nr. 101057978 INCYPROnext that exploits the research results of an ERC Proof of Concept project  INCYPRO.

ESF - European Science Foundation e FWO - Research Foundation Flanders

2024: FWO-FRP-2024_Sci-Tech, VLIR-iBOF 2024, FWO Strategic Basic Research (SBO), FWO-PDOC- 2024_Sci-Tech. 2023: FWO-Research-Project 23-FWO-FRP-0150. 2022: FWO-Research-Project 22- FWO-FRP-0792 e 22-FWO-FRP-0400. 2021: FWO-SBO-E-2021; FWO-SBO-ES-2021; FWO-SBO-M- 2021; FWO-BRC Brazil 2021; FWO-BRC China 2021. 2020: FWO-FRP-20_Med eFWO-FRP-20_Bio.

2019: FWO-FRP-19_Med e GE6 Contrats Doctoraux.

ERASMUS+

2019: Member of the panel to evaluate the Erasmus Mundus joint Master Degree SERP+ (for Qualifications in the European Higher Education Area - FQ-EHEA), a two-year programme in Surface, Electro, Radiation, and Photo-Chemistry with elements of Management, Business, Innovation and Valorisation, Communication and Patent law (Université Paris-Sud, Universidade de Porto, Università degli studi di Genova, Uniwersytet im. Adama Mickiewicza). Poznan (PL), June 1-3, 2019. 12-14 November 2018: Member of the training committee for the implementation of the European Approach to Quality Assurance of Erasmus Mundus Joint Master Degrees, Cologne (DE).

CANADA

CANADIAN INSTITUTES OF HEALTH RESEARCH

2022: Panel member per la valutazione dei progetti del Joint Canada-Israel Health Research Program Phase II Funding Opportunities: valutazione individuale di 7 progetti (13/05/2022-13/06/2022) e partecipazione a 3 comitati congiunti per la definizione della graduatoria dei progetti selezionati (20- 22/06/2022, online via zoom).

FRANCIA

2021-2024 e 2025-2028: Membro della Scientific Committee di ChimieParistech (Paris).

Conseil Nationale des Universités (CNU)

2016-2019: Eletta membro del CNU francese per le abilitazioni e le promozioni del personale docente (Maitre de Conférences e Professori) delle Università francesi (4 riunioni annuali in varie sedi universitarie in Francia).

Agence Nationale de la Recherche (ANR)

2019: Nominata membro della Scientific Evaluation Committee N° 44 “Biochemistry of  living  organisms ". ChâteauForm, République, 8 Bis Rue De La Fontaine Au Roi, 75011 Paris, January 14-15, 2019 and June 17-18, 2019. 2014: Nominata a far parte del panel di valutazione delle pre-proposal   per il processo di selezione di progetti da finanziare nel 2015 in Francia. 2010: Nominata dall'ANR a far parte quale membro esperto/rapporteur/lecteur del Comitato per la valutazione dei progetti presentati per i programmi Blanc (91 progetti) et Jeune Chercheurs/Jeunes chercheuses (37 progetti) del bando AAP Edition 2010 SIMI 7 (Chimie moléculaire, organique, de coordination, catalyse et chimie  biologique) (Paris, La Défense, commissione di valutazione in due step: gennaio 2010 e maggio2010).

Haut Conseil de l’Evaluation de la Recherche et de l’Enseignement Supérieur (HCERES)   2024:Membro del panel (in rappresentanza del CNU Section32) della HCERES per la commissione di valutazione dell'Unità di ricerca CiTCoM - Cibles Thérapeutiques et Conception de Médicaments, Vague D, UMR 8038, CNRS, Université Paris Cité (Gennaio 29-30, 2024), N. Leulliot: Director, I. Broutin : Deputy Director, P. Belmont : Deputy Director.

2020: Membro del panel (in rappresentanza del CNU Section 32) della HCERES per la commissione di valutazione Group A dell'Unità di ricerca “Institut de Biomolécules Max Mousseron”, Montpellier (Febbraio 25-28, 2020). 6-7/12/2017: Nominata dall’HCERES quale vice-presidente del Comitato per la Valutazione della ricerca e l'insegnamento Vague D dell’Unità di ricerca “Molecules of Communication and Adaptation of Microorganisms” (MCAM) UMR 7245 CNRS del Muséum National d’Histoire Naturelle (MNHN), Direttore P. Grellier.

Agence d’Evaluation de la Recherche et de l’Enseignement Supérieur (AERES)

Febbraio 2011: Nominata dall'AERES membro esperto del Comitato per la Valutazione della ricerca e l'insegnamento dell'"Institut de Chimie Moléculaire di Reims", Université de Reims Champagne  Ardenne, Direttore M.X. Coqueret. Marzo 2010: Nominata dall'AERES membro esperto del Comitato per la Valutazione della ricerca e l'insegnamento dell'"Institute of Biology and Technology" di Saclay (iBiTecc-S), Equipe "Service d'Ingénierie Moléculaire des Protéines" (SIMOPRO) CEA Saclay, Gif sur Yvette, Direttore V. Dive.

Fondation de la Recherche Médicale (FRM, Parigi)

2011 e 2012: Nominata Membro Esperto del Comitato per la Valutazione dei progetti presentati alla FRM - Appel d'offres 2011 e 2012 Programme Pionniers de la Recherche, Chimie pour la Médecine (valutazioni in due step Giugno e Dicembre 2011 e 2012). 2012-2016: Valutatore dei progetti selezionati in itinere.

LITUANIA

Research Council of Lithuania

Aprile-Giugno 2024: Member of the Expert Panel for the Research Council of Lithuania for the Call for proposals XIII CALL FOR PROPOSALS FOR THE IMPLEMENTATION OF RESEARCHER GROUPS PROJECTS

2023: Member of the Expert Panel for Comparative Expert Assessment of Research and Development Activities Carried out by Universities and Research Institutes in Lithuania, to evaluate the Unit of Assessments Biochemistry, Chemical Engineering (Biotechnology), and Chemistry of Vilnius University (Individual assessment: 2023-03-16 - 2023-04-19; Expert panel visits in Vilnius: 2023-04-24 - 2023-04-28; Summary assessment period: 2023-04-29 - 2023-05-31)

2022: Expert Panel commission for the Research Council of Lithuania for XII CALL FOR PROPOSALS  FOR THE IMPLEMENTATION OF RESEARCHER GROUPS PROJECTS FOR 2023-2026. Evaluation of 30 projects of Natural, Technical, and Medical Sciences.

2021: Leader of the expert Panel commission for the Research Council of Lithuania for the Call for proposals Promotion of Postdoctoral Fellows. Evaluation of 26 projects of Natural, Technical,  and Medical Sciences (March 8, 2021-May 13, 2021. 2 Steps, 2nd step on April 20, 2021 held remotely using Microsoft TEAMS platform). 2021: Leader of the expert Panel commission for the ResearchCouncil of Lithuania for the Call for proposals for Lithuanian-Polish programme. Evaluation of30 projects in the field of Natural, Technical, Agricultural, and Medical Sciences (February 3, 2021-March 24, 2021. 2 Steps, 2nd step on February 25, 2021 held remotely using Microsoft TEAMS platform). 2020: Member of the expert commission of the Research Council of Lithuania for the X Call for proposals for the Implementation of researcher groups projects for 2021-2024. Evaluation of 34 projects in the field of Natural, Technical, Agricultural, and Medical Sciences (November 17, 2020- January 30, 2021. 2 Steps, 2nd step on December 17, 2020 held remotely using Microsoft TEAMS platform). 2020: Leader of the expert panel commission for the Research Council of Lithuania for EEA Financial Mechanism 2014-2021, Baltic Research Programme, Call for Proposals in Lithuania, evaluation of 11 projects in the field of Natural, Technical, and Medical Sciences (July 1-9, 2020). 2020: Leader of the expert panel for the Research Council of Lithuania for the Evaluation of "Implementing World-class R&D Projects (SMART)" of 22 projects in the field of Natural, Technical, Medical andAgricultural Sciences (May 7-8, 2020). 2020: Member of the expert panel and acting as Leader of the expert panel for the Research Council of Lithuania for the “Distinguished Professor Programme”. Evaluation of 12 projects in the field of Natural, Technical,  Medical and Agricultural Sciences (February 1-March 5,  2020). 2019: Member of the expert commission of the Research Council of Lithuania for the Competitive Funding of Research and Dissemination Projects (evaluation of 27 projects). Two-stage evaluation process: 1st stage individual expert assessment of the proposal remotely (by March 17, 2019); 2nd stage participation at the panel assessment followed by the summary evaluation on March 22,2019,9:00-18:00,ResearchCouncilofLithuaniainVilnius(Gediminoav.3,Room212),Lithuania.

24-29/09/2018: Panel member as expert of bioorganic chemistry and chemical biology for assessment of research and development of the universities and research institutions of Lithuania in  the field of physical sciences.

ROMANIA

Executive Agency for Higher Education, Research, Development and Innovation Funding (U.E.F.I.S.C.D.I, Bucarest)

2021-2022: Expert reviewer & Rapporteur of funding applications for 8 projects: a) Programme 1 - Subprogramme 1.1. Human Resources: i) Postdoctoral Research Projects (PD-2021), ii) Research Projects for Young Independent Teams (TE-2021), and b) Programme 4 Fundamental and Frontier Research Exploratory Research Projects (PCE-2021). Domain 1) PHYSICAL SCIENCES AND ENGINEERING, Subdomains: a) PE4. Physical and Analytical Chemical Sciences: Analytical chemistry,chemical theory, physical chemistry/chemical physics, b) PE5. Synthetic Chemistry and Materials: Materials synthesis, structure-properties relations, functional and advanced materials, molecular architecture, organic chemistry; Domain 2 LS. LIFE SCIENCES, Subdomains: a) LS7. Applied Medical Technologies, Diagnostics, Therapies and Public Health: Development of tools for diagnosis, monitoring and treatment of diseases, pharmacology, clinical medicine, regenerative medicine, epidemiology and public health, b) LS9. Applied Life Sciences, Biotechnology, and Molecular and Biosystems Engineering: Applied plant and animal sciences, forestry, food sciences, applied biotechnology, environmental, and marine biotechnology, applied bioengineering, biomass and biofuels, biohazards).

SPAGNA

2024-2027: Nominata membro del Scientific Advisory Board dell'Instituto de Química  Médica  (Madrid). 4-5 online meetings (1-2 hours each, between June and October) to discuss research plans, methodologies, and future directions, an in-person visit on September 26th, 2024 concominantly with the ceremony commemorating IQM's 50th anniversary (October 27th, 2024). After this first period   (end October 2024) the participation will consist of one-two meetings per year for a followup.

2019-2026: Nominata 1 su 8 membri dell'External Scientific Advisory Board of The Institute for Advanced Chemistry of Catalonia (IQAC), del Spanish National Research Council (CSIC), devoted to research of excellence in Chemical Sciences, come leading scientist in peptide chemistry and the application of peptides in different fields (1st Meeting in Barcelona, Catalonia 25-26 November 2019, November 2024, and then remote meetings).

Maggio 2024 e Maggio 2025 ID CA46313ER: Evaluator per la Agency for Management of University and Research Grants, valutazione di una media di 15 progetti.

PORTOGALLO

Marzo-Luglio 2024 e Maggio-Ottobre 2025: Panel member per la Fundação para a Ciência e a Tecnologia, 2023 Call for Exploratory Research Projects in Chemistry, valutazione di 18/20 progetti come 1st e 2nd reader.

POLONIA

Gennaio-Aprile 2023: Panel member per il National Science Centre. Funding Scheme OPUS (addressed at researchers at any stage of their research career) + LAP (funding for foreign partners  and is organized in cooperation with foreign research teams from the Czech Republic, Austria, Slovenia, Germany, Switzerland Luxemburg and Belgium-Flandres). Three-step rocedure: stage 1: remote individual evaluation of projects and 27.02-28.02.2023 in person meeting in Krakow (PL) for ranking short list; stage 2: evaluation of external experts and 14.04.2023 on-line meeting on Webex for final ranking list and consensus reports for rejectedproposals.

26-27/07/2018: Panel member of the Foundation for Polish Science to select the winners of the First Team programme, edition 5/2018, Warsaw (PL).

SLOVENIA

Ministry of Education, Science, and Sport, Republic of Slovenia

2016: Nominata Membro del panel di valutazione dei progetti della sezione “Promotion of Research   and Development Programmes Implementation” (1 riunione a Ljubjana, Giugno 2016 per la selezione   di 1 progetto da circa 2 milioniEuro)

ATTIVITA' DI REVISORE IN COMITATI INTERNAZIONALI IN REMOTO

2017: Expert member for the German-Israeli Foundation (GIF) for Scientific Research and Development to evaluate projects presented at the GIF Regular Program. 2016: External Member of an “Ad Hoc Committee” for promotion review at The Scripps Research Institute (TSRI, USA) of candidates to the rank of Associate Professor with Tenure. 2016: Appointed evaluator for research projects submitted to the United States–Israel Binational Science Foundation (BSF).2016: Appointed External evaluator of candidates for Faculty Positions in the subject field “Organic Chemistry with emphasis on Chemistry” at the University of Patras (GR). 2015-2016: Appointed Reviewer for research projects submitted to the executive government agency of the Polish National Science Centre (Narodowe Centrum Nauki-NCN). 2014: Appointed reviewer for Vienna Scienceand Technology Fund (VSTF, Austria) to evaluate proposals submitted to the Vienna Research Groups  for Young Investigators call in the field of “Life Sciences”. 2014: Appointed reviewer for the National Science Centre in Poland (Narodowe Centrum Nauki - NCN)) to evaluate projects in the Funding scheme PRELUDIUM. 2011-2013: Appointed reviewer for the Association Nationale Recherche et Technologie (ANRT, Paris, France) to evaluate proposals “CIFRE” (Conventions Industrielles de Formation par la Recherche) to fund PhD fellowships to be perfomed 50% in industrial environments. 2012-2017: Referee for the Evaluation of the quality of the research of the Italian Universities -VqR.

MEMBRO DI COMMISSIONI DI CONCORSO IN ITALIA

Posizioni di Professore universitario di ruolo di seconda fascia

2021: Membro della commissione della procedura per la valutazione per la chiamata di n. 1 professore universitario di ruolo di seconda fascia, ai sensi dell'art. 24, comma 6, della Legge n. 240/2010, presso l'Universita degli Studi di Parma, per le esigenze del Dipartimento di SCIENZE DEGLI ALIMENTI E DEL FARMACO, SC 03/Cl Chimica Organica, SSD CHIM/06 Chimica Organica, indetta con Decreto Rettorale rep. DRD n. 265/2021 PROT. 34751 del 8.2.2021 (altri membri: Franca Zanardi e AnnaBernardi).

2021: Membro della commissione della procedura per la valutazione dei titolari d contratto aricercatore a tempo determinato di cui all’art. 24, Comma 3, Lettera B, Legge 240/2010 ai fini dell’inquadramento nella fascia dei professori associati riservato a Elena Cini (altri membri: Giovanni Piersanti e Adalgisa Sinicropi)

MEMBRO DI COMMISSIONI DI DOTTORATO E ABILITAZIONI A LIVELLO NAZIONALE E INTERNAZIONALE

COMMISSIONI ESAMI FINALI PER IL CONSEGUIMENTO DEL TITOLO DI DOTTORATO ALL'ESTERO

21 Aprile 2023: Valutatore esterno e presidente della commissione di esame finale della tesi di PhD in Industrial Chemistry and Chemical Engineering (CII), Politecnico di Milano di Alessandro Marchetti. Titolo:  HALOGENATED  AMYLOIDOGENIC  PEPTIDES:  FROM  SELFASSEMBLY  TO  HYBRID  MATERIALS. Politecnico di Milano. Febbraio 2023: External examiner della tesi di PhD in Biochemical Engineering della School of Biochemical Engineering of the Indian Institute of Technology of the Banaras Hindu University (Varanasi, India) di Mr Deepankar Sharma. Title: L-ASPARAGINASE PRODUCTION FROM MICROBIAL SOURCE, PURIFICATION, CHARACTERIZATION AND APPLICATION.

Marzo 2023: External rapporteur della tesi di PhD in Chemistry Ciclo 34 dell'Università degli studi di Salerno di Alicja Araszczuk. Title: MACROCYCLES: NEW PROPERTIES AND APPLICATIONS. 2021: Rapporteur della commissione di dottorato di Carole Deflers, Chatenay Malabry (FR), July 8, 2021. Title: Evaluation and Optimization of Targeting Systems for the Preferential Heart Delivery of Therapeutic Agents. PhD thesis of the Université Paris-Saclay, École doctorale n°569 : Innovation Thérapeutique: du fondamental à l’appliqué (ITFA). 2021: Membro della commissione di dottorato di Hendrik Rusche come Directrice de thèse, Cergy-Pontoise, April 12, 2021. Title: Aberrant immune response to xenobiotics triggering autoimmunity: the proof-of-concept of antibodies against biologics and non-typeable Haemophilus influenzae adhesin protein. PhD thesis of CY Cergy Paris Université, Ecole Doctorale Sciences et Techniques (online via Zoom). 2020: Examinatrice della commissione di dottorato di Bastien Petit,  Dijon (FR), December 2, 2020. Titre: Valorisation des produits naturels glycosyles pour la sante et l'environnement: du diagnostic de maladies autoimmunes a la protection des cultures. PhD thesis of Université de Bourgogne Franche-Comté, Ecole Doctorale de Pharmacie (online via Zoom). 2020:Membro della commissione di dottorato di Antonio Mazzoleni come Directrice de thèse, Paris(FR), March 20, 2020. Title: Glucosylated peptides in autoimmune diseases: synthetic strategies and application to antibody detection and capture. PhD thesis of Paris Sorbonne Université in cotutorate  with the University of Florence, Ecole Doctorale en Chimie prepared at Ecole Normale Supérieure and PeptLab at the Department of Chemistry of the University of Florence (online viaZoom).

Inoltre A.M. Papini é stata "Rapporteur" partecipando alle commissioni di ulteriori tesi di dottorato nel: 2011, 2016 & 2018 Ecole Doctorale en Chimie, Université Paris-Sud (FR); 2010, 2012 & 2013 Ecole Doctorale en Chimie, Université Pierre et Marie Curie, Paris (FR); 2012: PhD School in Chemistry della University of Montreal (Canada); 2010 Ecole Doctorale en Chimie, Université Montpellier 2 (FR); 2009 Ecole Doctorale en Chimie, Université de Bourgogne (FR); 2008, 2010 & 2011 Ecole Doctorale en Chimie, Université de Strasbourg (FR).

COMMISSIONI DI ESAME PER LA SELEZIONE DI DOTTORANDI IN ITALIA

Luglio 2025 Presidente delle Commissioni di esame per l'ammissione al Corso di Dottorato in Scienze Chimiche XLI ciclo dell'Università di Firenze: bando ordinario e bando EU-Joint Research Centre (JRC) . Luglio 2024 Presidente delle Commissioni di esame per l'ammissione al Corso di Dottorato in Scienze Chimiche XL ciclo dell'Università di Firenze: bando ordinario e Borse DM 351 e 352.

Luglio-Settembre 2023 Presidente delle Commissioni di esame per l'ammissione al Corso  di  Dottorato in Scienze Chimiche XXXIX ciclo dell'Università di Firenze: bando ordinario e Borse DM 117 e 118.

Agosto 2022 Presidente della Commissione di esame per l'ammissione al Corso di  Dottorato  in Scienze Chimiche XXXVIII ciclo dell'Università di Firenze: bando ordinario e Borse DM352.

Novembre 2022 Presidente della Commissione di esame per l'ammissione al Corso di Dottorato in Scienze Chimiche XXXVIII ciclo dell'Università di Firenze: bando Borse su finanziamenti PNRR. Novembre 2021: Presidente della Commissione di esame per l'ammissione al Corso di Dottorato in Scienze Chimiche XXXVII ciclo dell'Università di Firenze: bando su tematiche PON Ricerca  e  Innovazione 2014-2020 (D.M 1061/2021) per dottorati d'interesse industriale. Settembre 2021: Presidente della Commissione di esame per l'ammissione al Corso di Dottorato in Scienze Chimiche XXXVII ciclo dell'Università di Firenze: bando ordinario. Agosto-Settembre 2018: Membro della commissione di esame per l'ammissione al Corso di Dottorato in Scienze Chimiche XXXIV ciclo dell'Università di Firenze.

COMMISSIONI DI ESAME PER L'ATTRIBUZIONE DEL TITOLO DI HDR ("HABILITATIONS A DIRIGER LES RECHERCHES")

2008: Rapporteur" della commissione di esame presso l'Université de Strasbourg (FR) e 2011: Rapporteur" della commissione di esame presso l'Université Pierre et Marie Curie, Paris (FR).

ATTIVITA' EDITORIALE

Dal 2025 ad oggi: Editor-in Chief di Protein & Peptide Letters, Bentham Science Publishers Ltd. (https://www.benthamscience.com/journal/51/download_flyer)

Dal 2025 ad oggi: Editor-in Chief di Current Protein and Peptide Sciences, Bentham Science  Publishers Ltd.(https://www.benthamscience.com/journal/42/download_flyer)

Dal 2005 al 2024: Editor-for-Europe di Protein & Peptide Letters, Bentham Science Publishers Ltd.  Dal 2018 al 2024: Associate Editor di Current Protein and Peptide Sciences, Bentham Science Publishers Ltd. Dal 2013 al 2018: Membro dell'Editorial Advisory Board di Current Protein and Peptide Science, Bentham Science Publishers Ltd. Dal 2008 ad oggi: Membro dell'Editorial Advisory Board del Journal of Peptide Science, Wiley Publisher. Dal 2005 ad oggi: Membro dell'Editorial Advisory Board dell'International Journal of Peptide Research and Therapeutics. Dal 2003 ad oggi: Membro dell'Editorial Advisory Board di International Journal of Peptide Research and Therapeutics, Springer.  Dal 2017 ad oggi: Membro dell'Editorial Board di Biosensors – Open Access Jounal MDPI (ISSN 2079- 6374; CODEN: BIOSHU. Dal 2018 ad oggi: Review Editor di Frontiers in Chemistry – Chemical   Biology Open access publisher. 2007-2016: Membro dell'Editorial Board di Chemistry Today, Editor Teknoscienze. Dal 2004 ad oggi: Membro dell’Editorial Advisory Board di Current Drug Delivery, Bentham Science Publishers Ltd.(http://www.bentham.org/cdd/index2.htm).

PARTECIPAZIONE A SCIENTIFIC ADVISORY BOARD, SOCIETA' SCIENTIFICHE, ORDINI PROFESSIONALI E ASSOCIAZIONI NO-PROFIT

2014-2020: Membro del Scientific Advisory Board di Regulaxis (www.regulaxis.com). Dal 2000: Membro fondatore della European Society of Combinatorial Sciences. 2009-2020: Consigliere eletto dell'Ordine dei Chimici della Toscana. 1987-2018: Membro della Società Chimica Italiana (SCI) e della Divisione di Chimica Organica. Dal 1993: Membro fondatore della Divisione di Chimica dei Sistemi Biologici della SCI. Dal 1988: Membro fondatore della American Peptide Society (APS). Dal 1988 : Membro della European Peptide Society (EPS). Dal 1988: Membro della Federation of American Societies for Experimental Biology (FASEB).

Membro del Board di Società scientifiche

2019-2025 : Eletta Councilor della American Peptide Society . 2011-2020: Eletta Tesoriere e membro dell’Executive Board della European Peptide Society (EPS). A.M. Papini ha contribuito a un aumento dei fondi della EPS da 97.000,00 a 250.000,00 Euro grazie ai nuovi accordi conWiley (royalties del Journal of Peptide Science), BCN, Curran Associates (per cessione dei contributi sui Proceedings degli EPS). 2017-2021: Eletta membro dell’Executive Board e scientific officer della Italian Peptide Society. 2004-2008:Nominata membro della Scientific Affairs Committee della European Peptide Society. 2000-2013: Nominata rappresentante accademico per l’Italia nel Board della Society of Combinatorial Chemistry.

ATTIVITA’ DIDATTICA PRESSO LA SCUOLA DI SMFN DELL’UNIVERSITA’ DI FIRENZE

Dal 2021/2022 ad oggi: Laurea Triennale in Scienze Biologiche B005: Titolare del Corso di Chimica Organica (B006416, 3/6 ECTS, Cognomi M-Z).

Dal 2019/2020 ad oggi: Laurea Magistrale in inglese "Advanced Molecular Sciences LM 54": Titolare del Corso "Advanced synthetic methods" (B029593, 3/6 ECTS).

Dal 2010/2011 ad oggi: Laurea Magistrale in Scienze Chimiche B088, LM 54, curriculum in Chimica delle Molecole Biologiche: Titolare del Corso Chimica delle Biomolecole (B012715, 6 ECTS); curriculum in Sintesi, struttura e proprietà di molecole organiche: Titolare del Corso Chimica Bioorganica  (B012895, 6 ECTS).

2002/2007: Laurea Triennale in Chimica B025 (6 ECTS): Titolare del Corso Laboratorio di Chimica Organica I.

2007/2009: Laurea Specialistica in Chimica delle Molecole Biologiche: Titolare del Corso Chimica Bioorganica con Laboratorio (6 ECTS).

Dal 2023/2024 ad oggi: Docente del percorso formativo abilitante da 60 CFU, PF60, per l'insegnamento della chimica organica nei licei (8h/anno)

ATTIVITA’ DIDATTICA PRESSO LA SCUOLA DI SCIENZE PER L'ECONOMIA E MANAGEMENT DELL’UNIVERSITA’ DI FIRENZE

Dal 2022/2023 ad oggi: Laurea Triennale DM 270/04 in inglese "Sustainable business and societal challenges B247": Corso "Sustainable, environmental chemistry and technology for circular economy (with LAB)" (B031720, 4/12 ECTS).

RELATORE/CORRELATORE DI TESI DI LAUREA TRIENNALE (LT) E MAGISTRALE (LM) E TUTORE DI DOTTORATI DIRICERCA

2001/2025 Tutore di 48 dottorandi di ricerca in scienze chimiche (44 tesi finalizzate e 4 in corso), relatore di 88 tesi di LM in Scienze Chimiche, 29 tesi di LT. Tutore di studenti Erasmus: 40 studenti Erasmus Traineeship per periodi di 4-12 mesi (37 finalizzati e 3 in corso).

ATTIVITA’ DIDATTICA INNOVATIVA IN ITALIA

2016-2026: Coordinatore con il Prof. V. Schettino (Accademico dei Lincei) del corso di formazione per insegnanti delle Scuole secondarie superiori: Aspetti multidisciplinari nell’insegnamento delle Scienze, Polo Firenze - I Lincei per una nuova didattica nella Scuola, Fondazione I Lincei per la Scuola, Accademia Nazionale dei Lincei(https://www.linceiscuola.it/firenze/)

2020: Membro del panel di valutazione dei finalisti di FameLab 2020 (7 Marzo 2020): “Talent in  science” competizione internazionale di giovani ricercatori e studenti di dottorato coinvolti in attività di disseminazione, OpenLab, Psiquadro, e British Council Italy (i primi due classificati hanno partecipato alla Masterclass in science communication della competizione internazionale a Cheltenham, UK, June 4- 5, 2020.

2010-2012: Direttore del Corso di Specializzazione per la Professione di Chimico, Facoltà di SMFN dell’Università di Firenze in collaborazione con l’Ordine dei Chimici della Toscana.

2010-2011: Organizzatore del Corso Rischio Chimico per Vigili del Fuoco della Regione Toscana in collaborazione con OpenLab e Ordine dei Chimici dellaToscana.

2010: Organizzatore del Corso in Spettrometria di Massa per Vigili del Fuoco della Regione Toscana in collaborazione con OpenLab e Ordine dei Chimici dellaToscana.

2002-2003: Membro del Consiglio direttivo e della commissione didattica del Master II livello “Innovative Synthetic Methodologies” della Facoltà di SMFN dell’Università di Firenze.

2002: Membro del Comitato organizzatore dell’ Open day” del Dipartimento di Chimica, XII Settimana della Cultura Scientifica in Toscana.

2001-2016: Organizzatore delle attività di chimica per il progetto OpenLab: disseminazione delle Scienze presso il Polo Scientifico e Tecnologico dell'Università di Firenze dedicata a studenti da 3 a 18 anni delle Scuole di ogni ordine e grado in Toscana.

1986-1990: Formatore di Chimica per insegnanti delle scuole primarie per il Progetto IRRSAE in Toscana.

INTERESSI DI RICERCA

PEPTIDE AND PROTEIN ORGANIC CHEMISTRY. Development of synthetic solid-phase strategies. Microwave- and induction-assisted peptide synthesis. Bioorganic chemistry of peptides and proteins. Synthetic & semi- synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (constrained amino acids, glycosyl and lipophilic amino acids). Coupling reagents for peptide chemistry (amide and ester bond formation). Side-chain to side-chain peptide cyclisation, i.e., lactams, dicarba analogs, triazolyl-based cyclization, Glaser cyclization, etc., to mimic bioactive secondary structures for SAR studies (PTH, MT, Octreotide, Oxytocin, etc.)

CHEMICAL IMMUNOLOGY. Characterization of aberrant post-translational modifications (glycosylation, glycation, lipoylation, etc.) in antigens triggering immune-mediated diseases (Multiple Sclerosis, T1D, PBC, coeliac disease, rheumatoid arthritis, Rett Syndrome, Metabolic disorders, etc.) to characterize antibodies. Characterization of anti-drug antibodies. Study of the molecular mechanisms   of immune-mediated diseases. Cross-reactions with infectious diseases, i.e., bacterial and/or viral infections.

ROLE OF PHTALATES AND OTHER ENVIRONMENTAL POLLUTANTS IN ENDOCRINE DISRUPTION: Characterization by HPLC and GC-MS of EDCs (particularly from microplastics) in biological fluids (breast milk, urine, blood) and infant food for clinical correlation studies with metabolic diseases and autistic spectrum disorders in children (in cooperation with pediatricians from the Università di Parma, Azienda Ospedaliera di Reggio Emilia, Università di Cagliari).

INDUSTRIAL APPLICATIONS AIMED TO TECHNOLOGY TRANSFER: In vitro Diagnostics and peptide biomarkers. Glycoconjugates and PTM antigens as diagnostic and prognostic tools  for  human, animal, and plant diseases. IVDs for autoimmune diseases. Characterisation of biomarkers of disease activity. R&D of diagnostic/prognostic tools, immunotherapies, apheresis technologies. In vivo Diagnostics and imaging techniques. DOTA peptide analogues for cancer pre-targeting diagnosis & therapy. FIV peptides for the development of an anti-retroviral therapy for felines. Cultural heritage. Peptide-based immunoassays for characterization of glues, in particular collagen. Peptide Nutraceuticals and cosmeceuticals. Spiruline. Fish feed. Peptides involved in collagen turnover. Development of processes for large-scale and green solid-phase  peptide  synthesis. Production of active pharmaceutical peptide ingredients byMW-technology.

SNAP-SHOT DEL TEAM PEPTLAB (Giugno 2025)

12 studenti PhD, 2 Tecnologi di ricerca, 1 Ricercatore CNR-ICCOM, 2 Professori ordinari, 1 Professore Associato, 4 Laureandi Magistrali, 2 studenti PhD Erasmus+ traineeship, 2 dottorandi in cotutela

PUBBLICAZIONI E COMUNICAZIONI DELL’ATTIVITÀ SCIENTIFICA

PARAMETRI    BIBLIOMETRICI    (10/06/2025)    ORCID:    0000-0002-2947-7107.    Research   ID 7005551589.WOS data - Total publications: 404. h-index: 33. Citazioni totali: 3938. Sum of times cited by patents: 122. Citing patents:103. SCOPUSdata-Documents: 220. h-index: 34. GOOGLE SCHOLAR - Citazioni: 5353. h-index: 40. i10-index 125. A.M. Papini é coinventrice di 11 brevetti. La lista totale dei contributi è disponibile a www.peptlab.unifi.it e https://www.unifi.it/p-doc2-0-0-A-3f2a3d2b3b302b.html

SEMINARI E CONFERENZE SU INVITO

2000-2025: 165 conferenze su invito per plenary, keynote o award lectures presentate a congressi internazionali, presso Università o Centri di ricerca Internazionali (EU, USA, Canada, Australia, Israele, Giappone, Nord-Corea, Cina), di cui 30 conferenze su invito su tematiche di trasferimento tecnologico nello spazio globale della Ricerca e Sviluppo e 3 webinar.

COMUNICAZIONI ORALI E POSTER A CONGRESSI INTERNAZIONALI

1985-2025: 76 comunicazioni orali e 295 comunicazioni poster sono state selezionate a Congressi nazionali e internazionali e presentate anche da dottorandi e assegnisti di cui A.M. Papini è stata responsabile scientifico.

Firenze (Italia), 11 Giugno 2025

Invited Lectures at Universities, Research Centres and National/International Symposia

(Period 2000-2025)

 Legenda: Total 128 Invited Lectures: IL: Invited Lecture; KL: Invited Keynote Lecture; PL: Invited Plenary Lecture; AL: Award Lecture; S: Invited Seminar; ILTT: Technology Transfer Invited Lecture.

2000

[Inv1] IL1: 1st Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 1-3, 2000. March 1, 2000: Lecture invited by the Chair Prof. J. Matsoukas. Title: Synthesis of post-translational modified peptide and non-peptide analogues of MBP/MOG myelin antigens in multiple sclerosis research.

2001

[Inv2] IL2: 2nd Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 1-3, 2001. March 1, 2001: Lecture invited by the Chair Prof. J. Matsoukas e Prof. P. Cordopatis. Title: Specific role of Asn(Glc) in autoantibody recognition to glycosylated peptides: towards new immunotherapeutic drugs for the treatment of Multiple Sclerosis.

2002

[Inv3] PL1: 3rd Conference“Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras, Greece, March 7-9, 2002. March 7, 2002: Plenary “Memory Lecture in Honour of Marco Vergelli for his contributions to Multiple Sclerosis Research” invited by the Chairs Prof. J. Matsoukas and Prof. P. Cordopatis. Title: A very promising Cyclic MBP Peptide for Multiple Sclerosis.

[Inv4] PL2: European Commission-funded Intensive Course: “Synthesis for Solving Biological Problems”,Henderson Hall,Newcastle upon Tyne (United Kingdom), August 3-10, 2002. August 3, 2002: Plenary Lecture invited by the Chair Prof. Bernard Golding. Title: Synthesis of post-translationally modified peptidesof myelin proteins. The contribution of bioorganic chemistry to the diagnosis and immunotherapy of the autoimmune disease multiple sclerosis ».

2003

[Inv5] S1: Institut de Biologie Moléculaire et Cellulaire, Strasbourg (France). Seminar invited by Dr. Jean-Paul Briand, February 21, 2003, h. 9 :30, Salle des Séminaires. Title: CSF114(Glc): the glycopeptide detecting autoantibodies in multiple sclerosis. MS PepKit, the first diagnostic test to follow-up the disease activity.

[Inv6] S2:INSERM E209, Hôpital Saint-Antoine, Bâtiment Raoul, Paris (France). Seminar invited by Dr. Claude Carnaud, June 23, 2003. Title: Contribution of peptide chemistry to study the autoimmune disease multiple sclerosis.

[Inv7] S3: Journée de l’Ecole Doctorale: Du Matériau à l’Interface Chimie-Biologie, Université de Paris-Sud, Bâtiment 338, Paris (France). Seminar invited by Prof. Yves Langlois, September 19, 2003. Title: Contribution de le chimie bioorganique à l’étude d’une pathologie auto-immune: cas de la sclérose en plaque. 

[Inv8] S4: 1st Pratical Training Course “Innovative combinatorial approaches and technologies”, ComGenex, Budapest (Hungary) & Polo Scientifico, Università di Firenze, Firenze (Italy), April 9-11, 2003. April 11, 2003: Seminario su invito del Dr. Ferenc Darvas, ComGenex, Budapest. Title: A combinatorial approach for the rational design of innovative diagnostic tools for autoimmune diseases.

[Inv9] IL3: Italian-German Mini Symposiumon Peptides and Proteins. “Structure and Molecular Recognition”, Max Planck Institut für Biochemie, Kleiner Hoersaal, Bauteil T, Martinsried (Germany). December 5, 2003: Lecture su invito del Prof. Luis Moroder. Title: Development of the innovative designed glycopeptide CSF114(Glc) as prognostic tool for the characterizationof an antibody-mediated multiple sclerosis subgroup. 

2004

[Inv10] IL4: 5th Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 11-13, 2004. March 11, 2014: Lecture su invito del Chair Prof. J. Matsoukas. Title: Development of the innovative designed glycopeptide CSF114(Glc), as prognostic tool for the characterization of an antibody-mediated multiple sclerosis subgroup.

[Inv11] IL5: 9th Naples Workshop, Peptides as Therapeutic, Diagnostics & Vaccines, Villa Orlandi, Anacapri (Italy), May 8-11, 2004. May 9, 2004: Lecture su invito del Chair Prof. Ettore Benedetti. Title: Peptide-based immunoassays for the diagnosis of autoimmune diseases. 

[Inv12] S5: Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon (France), June 11, 2004 : Seminario su invito del Prof. Sylvain Jugé. Title: Solid-phase strategy to cyclic structures.

[Inv13] S6: D.E.A (Diplôme d’Etude Avancés): Microbiologie-Enzymologie-Nutrition (Aspects Moléculaires et Cellulaires), Magistére Microbiologie-Enzymologie (3éme année). Module Biophysique et Biologie Structurale, Université Henry Poincare, Nancy 1, Faculté des Sciences et Techniques, Nancy (France), December 3, 2004 : Seminario su invito del Dr. A. Aubry e dal Prof. B. Vitoux. Title : Peptides portants des modifications post-traductionnelles pour le diagnostic et la thérapie de pathologies autoimmunes.

2005

[Inv14] S7: Weizmann Institute of Science, Rehovot (Israel), January 18, 2005: Seminario su invito del Prof. M. Sela (Past President del Weizmann Institute e inventore del farmaco Copolymer1. Title: Glycosylated synthetic probes to detect disease-specific autoantibodies, biomarkers of Multiple Sclerosis.

[Inv15] IL6: 4thEuropean-Japanese Bioorganic Meeting & Chemical Biology COE Program sponsored by Okayama University, Hotel Limani, Ushimado, Setoucvhi, Okayama-Pref. (Japan), March 15-19, 2005. March 17, 2005: Lecture su invito del Prof. Tetsuo Toraya. Title: CSF114(Glc): the first synthetic glycopeptide probe to follow-up disease acrivity in Multiple Sclerosis patients.

[Inv16] S8:Seminaris del Parc Cientific de Barcelona 2005, Universitat de Barcelona (Spain),  May 19, 2005: Seminario su invito del Prof. Fernando Albericio. Titolo: A combinatorial approach for the rational design of innovative prognostic tools for multiple sclerosis.

[Inv17] S9: Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon (France), May 2, 2005 : Seminario su invito del Prof. Claude Moise. Title: Les bases de la synthése peptidique.

[Inv18] S10: Conférences de l’Institut de Chimie des Substances Naturelles, CNRS-UPR2301, Bâtiment 27, Gif-sur-Yvette (France), 7 Julliet, 2005 : Seminario su invito del Direttore dell’ICSN Prof. Jean-Yves Lallemand. Title: Les glycopeptides pour le développement de tests prognostiques innovatifs pour suivre la sclérose en plaque: vers un traitement thérapeutique nouveau.

2006

[Inv19] S11:Doctorate School in Chemical Sciences, Università di Siena. Symposium on Metal Ions and Neurodegeneration,Scientific Campus of S. Miniato, Via A. Moro, Siena Room 14. January 31, 2006: Seminario su invito dellla Prof. Elena Gaggelli a nome del Collegio dei Docenti del Dottorato. Title: Aberrant glucosylation triggering autoimmunity in multiple sclerosis.

[Inv20] IL7:Symposium on Recent Advances in Synthesis and Chemical Biology V. Center for Synthesis and Chemical Biology. O'Flanagan Theatre, Royal College of Surgeons in Ireland (RCSI), Dublin (Ireland), December 15, 2006: Invited by Prof. Kevin B. Nolan. Title: An Innovative Chemical Reverse Approach to the Discovery of Specific Biomarkers of Autoimmune Diseases.

[Inv21] IL8: 7th Conference “Medicinal Chemistry: Drug Design and Design”, Conference and Cultural Centre, University of Patras (Greece), March 8-11, 2006. March 9, 2016: Invited by the Chair Prof. J. Matsoukas. Title: Diagnostics and Prognostic Tools in Multiple Sclerosis.

2007

[Inv22] PL3:Israeli-Italian Bi-National Conference Brain functions: from Basic Reasearch to clinical Applications, Weizmann Institute of Science, Rehovot (Israel), March 14, 2007: Plenary Lecture invited by Prof. M. Tsodyks. Title: A chemical reverse approach to biomarkers of neurological disorders.

[Inv23] S12:Department of Biological Chemistry, Judea & Samaria College, Ariel (Israel),March 15, 2007:Invited by Dr. Gary Gellerman. Title: An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis from follow-up of disease activity to specific therapeutic treatments.

[Inv24] PL4:6^th Congress of the Israeli association for Medicinal Chemistry, Weizmann Institute of Science, Rehovot (Israel), March 18, 2007.Plenary Lecture invited by Prof. M. Fridkin. Title: A chemical Reverse Approach to detect biomarkers of autoimmune diseases (Bulletin of the Israel Chemical Society N. 23/January 2008).

[Inv25] S13:Bar-Ilan University, Department of Chemistry,Ramat-Gan (Israel), Special Seminar March 19, 2007.Invited by Prof. Gerardo Byk. Title: Optimized synthetic strategies to glycopeptides for the development of a diagnostic/prognostic test for Multiple Sclerosis.

[Inv26] S14:Istituto di Biofisica- Unità Operativa di Pisa. Area Ricerca Pisa- S. Cataldo, Pisa (Italy). May, 2, 2007. Invited by Dr. Santi Chillemi. Title: A chemical reverse approach to decte autoantibodies as biomarkers of autoimmune diseases.

[Inv27] IL9: Modern Solid Phase Peptide Synthesis & its applications. An official satellite meeting of the 7^th International Australian Peptide Symposium, Port Douglas (Australia), October 17-20, 2007. October 18, 2007. Invited by Prof. J. Wade. Title: N-Triazinylammonium coupling reagents: from the concept of superactive esters to a versatile assistance for peptide synthesis.

[Inv28] S15:Howard Florey Institute, University of Melbourne, Melbourne (Australia), October 29, 2007. Invited by Prof. John Wade. Title: An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis: from an efficient follow-up of disease activity to a guide for specific therapeutic treatments. 

[Inv29] S16:Burnet Institute, Austin Campus, Heidelberg (Australia), October 31, 2007. Invited by Prof. V. Apostolopoulos. Title: Strategies for characterisation of a Multiple Sclerosis pattern disease based on specific autoantibodies as biomarkers.

2008

[Inv30] IL10: Third ERA Chemistry Flash Conference: Carbohydrates at the interfaces of biology, medicine and materials science. ERA-Chemistry “A Network of research councils for the development and implementation oif joint bottom-up European programmes for curiosity driven research”, Embarkinitiative, Killarney (Ireland), 9-13 March, 2008. March 13, 2008. Invited by Prof. S. Oscarson and Prof. P. Murphy. Title: Aberrant glycosylations as biomarkers of autoimmune diseases correlating with disease activity: toward the development of reliable diagnostic/prognostic tools.

[Inv31] AL1: 6^th Hellenic Forum on Bioactive Peptides, The Conference and Cultural Centre of the University of Patras (Greece), May 18-20, 2008. May 18, 2008: 1st Dimitrios Theodoropoulos Memorial Lecture Award by the Hellenic Peptide Society to A.M. Papini in recognition of her significant contribution to the advancement of peptide science and especially in peptide chemistry. Title: A “Chemical Reverse Approach” to modified peptides as synthetic antigenic probes to detect autoantibodies as biomarkers of multiple sclerosis.

[Inv32] IL11: 5th Bulgarian Peptide Symposium, Rila Mountain (Bulgaria), 28-30 May 2008. May 30, 2008.Invited by Prof. L. Vezenkov. Title: Post-translationally modified peptides to develop reliable diagnostic/prognostic assays to follow up autoimmune diseases.

[Inv33] AL2: 30th European Peptide Symposium 31 Agosto-5 Settembre  2008, Helsinki (Finland). 31 Agosto 2008: Leonidas Zervas Memorial Lecture Award 2008attributed by the European Peptide Society to A.M. Papini for her outstanding achievements in peptide science (in commemoration of L. Zervas and the outstanding contributions he made to peptide chemistry nominated by the European Peptide Society). Title: Peptide-based immunoassays for biomarkers detection: a challenge for translational research.

[Inv34] S17:Istituto Clinico Humanitas Centro di Ricerca e Didattica, Rozzano, Milano (Italy). December 17, 2008. Invited by Prof. Carlo Selmi. Title: A Chemical Reverse Approach to Detect Biomarkers of Autoimmune Diseases: a Challenge for Translational Research.

[Inv35] IL12: 6th International Microwaves in Chemistry Conference, Cambridge Mariott@MIT, Cambridge, MA (USA), May 13-16, 2008. May 14, 2008. Invited by Prof. Stephen L. Buchwald and Prof. Camille Dreyfus. Title: Optrimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostic/prognostic immunoassays.

2009

[Inv36] S18: Barcelona Biomedical Research Park PRBB-CRG Seminar, Pompeu Fabra University, Barcelona (Spain). February 23, 2009. Invited by Prof. David Andreu.Title: Peptide-based Immunoassays for Biomarkers Detection: a Challenge for Translational Research.

[Inv37] S19: Master di II livello in “Progettazione e Sviluppo di Farmaci”. Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici. Università degli Studi di Pavia (Italy). April 17, 2009. Invited by Prof. Ornella Azzolina.Title: Recenti progressi nella sintesi di peptidi d’interesse biomedico.

[Inv38] PL5: MAOPS, International Symposium on Microwave-Assisted Organic and Peptide Synthesis 2009, La Grande Motte (France). June 4-5, 2009. June 4, 2009. Invited by Dr. Gilles Subra.Title: Optimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostics.

[Inv39] PL6: 11th International Congress on Amino Acids, Peptides and Proteins, Vienna (Austria). August 3-7, 2009. August 6, 2009. Prominent speaker and Plenary Lecture invited by Prof. Norbert Sewald.Title: Glycated and glycosylated amino acids for Solid-Phase GlycoPeptide Synthesis: a challenge to microwave-assisted strategies for R&D diagnostics of autoimmune diseases.

[Inv40] PL7:Fundacion BBVA – IRB Barcelona BioMed Conference on “Peptide engineering: Therapeutic peptides”, October 26-28, 2009. October, 28, 2009. Invited by Prof. Ernest Giralt and Prof. Claudio Toniolo.Title: Click chemistry reaction: a challenge for peptide engineering to develop efficient drugs and diagnostics.

[Inv41] IL13: Does size matter? Beyond small molecule therapeutics: challenges and success stories”, Université Libre de Bruxelles, Salle Dupéel, Avenue Jeanne 44, Brusselles (Belgium). November 6, 2009: Distinguished speaker invited by Dr. Edmond Differding (President of the Medicinal Chemistry Division, SRC) e del Prof. Koen Augustyns (President, Division for Medicinal and Bioorganic Chemistry, KVCV).Title: Synthetic post-translationally modified peptides for the discovery of new biomarkers of autoimmune diseases: a “Chemical Reverse Approach”.

[Inv42] S20: Prefectural University of Osaka (Japan). November 12, 2009. Invited by Prof. Ikuo Fujii.Title: Post-translationally modified peptides for detection of biomarkers of immune-mediated diseases: A “Chemical Reverse Approach”.

2010

[Inv43] PL8: XII Convegno-Scuola sulla Chimica dei Carboidrati, Gruppo Interdivisionale Chimica dei Carboidrati della S.C.I. Pontignano (Siena). June 20-23, 2010. June 21, 2010. Invited by Prof. Michelangelo Parrillo on behalf of the scinetific committee. Title: Glycated and glycosylated amino acids for solid-phase glycopeptide synthesis: a challenge for R&D diagnostics of neurodegenerative diseases.                     

[Inv44] S21: Université de Versailles, Saint Quentin en Yvelines (France). November 4, 2010.Invited by Prof. Francois Couty.Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[Inv45] IL14: Juvenil Diabetes Research Foundation Workshop “Role of Beta Cell Antigen Modifications in the Pathogenesis of T1D and their Diagnostic and Therapeutic Potential”,New York (USA). December 13th, 2010. Invited by the scientific committee. Title: A “Chemical Reverse Approach” to detect autoantibodies as biomarkers of autoimmune diseases: a challenge for theragnostics.

2011

[Inv46] S22: iBiTec-S, CEA/Saclay, Gif sur Yvette (France). January 25, 2011. Invited by Dr. Bernard Rousseau. Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics".

[Inv47] S23: ICOA - UMR 6005 / Université d'Orléans, Orleans (France). March 30, 2011. Invited by Prof. Patrick Rollin. Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[Inv48] S24:Lessons for the « Cycle thématique de l’Université de Cergy-Pontoise » :. "Dynamiques  des systèmes complexes: Modélisation de macromolécules biologiques", St  Martin, Université de Cergy-Pontoise (France).March 31, 2011. Invited by the Chair Prof. Roberto Livi. Title: 3D structures mimicking protein biological activity: from a rational design to peptide-based diagnostics and therapeutics.

[Inv49] S25: Master 2nd level “Progettazione e Sviluppo di Farmaci: Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici”. Università degli Studi di Pavia, Pavia (Italy). April 15, 2011. Invited by Prof. Ornella Azzolina.Title: “Approcci sintetici per indurre strutture secondarie e modulare l'attività biologica di peptidi”.

[Inv50] S26: Neonatology and beyond, Sala Universitaria - Palazzo Granafei Nervegna, Brindisi (Italy). 14 May 2011. Invited by the Chair Dr. Giuseppe Latini. Title: Ricerca di biomarcatori nelle malattie mediate dal sistema immunitario. Corso di aggiornamento per attribuzione di crediti ECM.

[Inv51] S27:Ecole Doctorale, Université de Montpellier (France). May 26, 2011. Invited by the Dean of the Faculty of Pharmacy Prof. Jean Martinez. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[Inv52] IL15:Italian-German Meeting: Green and SustainableApproach to Process Intensification, Torino (Italy), 2-3 June 2011. June 3, 2011. Invited by the Chair Prof. Giancarlo Cravotto. Title: Efficient synthetic strategies aimed to R&D of diagnostics.

[Inv53] S28:INSERM U829, Laboratoire SABNP "Structure-Activité des Biomolécules Normales et Pathologiques" Université d'Evry-Val d'Essonne (France). June 7, 2011. Invited by Prof. Flavio Toma. Title : A « Chemical Reverse Approach » to develop efficient diagnostic/prognostic assays for immune-mediated diseases.

[Inv54] IL16: Gordon Research Conference – Carbohydrates, Colby College, Waterville, ME (USA), June 19-24, 2011. June 21, 2011. Invited by theChairs Robert J. Woods and Nicola Pohl.Title: The “Chemical Reverse Approach” to develop glycopeptides as synthetic antigens characterising autoantibodies as biomarkers of neurodegenerative diseases. https://www.grc.org/carbohydrates-conference/2011/

[Inv55] S29: Dipartimento di Scienze della Vita, Università degli Studi di Trieste, Trieste (Italy). July 25, 2011. Invited by theDirector of the Dipartimento di Scienze della Vita Prof. Renato Gennaro.Title: A « Chemical Reverse Approach » to develop efficient and reliable diagnostics for immune-mediated diseases.

2012

[Inv56] IL17: Gordon Research Conference: Peptides, Chemistry & Biology of Peptides as Signals, BioMaterials and Therapeutics. Ventura Beach Marriott, Ventura, CA (USA) February 19-24, 2012.February 21, 2012. Discussion Leader invited by the Chairs Prof. Fred R. Naider andMaria A. Bednarek. Session: Peptide Vaccines.

[Inv57] PL9: 1^st See-Drug Workshop From chemical to systems biology – Peptide synthesis and protein production May 9-10, 2012, Patras (Greece). May 9, 2012. Invited by the Chair Prof. Georgios A. Spyroulias. Title: The importance of a “chemical reverse approach” to modulate secondary structures inducing specific and high affinity biological recognition.

[Inv58] S30:Scuola di Dottorato, Aula 1, Edificio E della Presidenza della Facoltà di Scienze dell'Università di Pisa, Via Buonarroti 1, Pisa (Italy). May 28, 2012. Invited by Dr. Federica Chiellini. Title: Problem solving in diagnostics of immune-mediated diseases: a Chemical Reverse Approach.

[Inv59] KL1: 13th Naples Workshop on Bioactive Peptides. Conformation and activity in peptides: relationships and interactions, Aula Magna Partenope, Napoli (Italy), June 7-9, 2012. June 9, 2012. Invited by the Chairs Prof. Giancarlo Morelli and Dr. Michele Saviano.Title: The mimicry pathway from glycopeptides to specific protein antigens of autoimmune neurodegenerative diseases. http://www.cirpeb.unina.it/naples2012/NW2012.pdf

[Inv60] PL10: Saxon Biotechnology Symposium, Centre for Biotechnology and Biomedicine (BBZ), Universitaet Leipzig and Biotechnology Center (BIOTEC) of the Technical University of Dresden, Deutscher Platz 5, 01403 Leipzig (Germany), June 20, 2012: Plenary Lecture invited by the Director of the Biotechnologisch-Biomedizinisches Zentrum, Prof. Dr. Andrea Robitzki. Title: Post-translational modified peptides to develop efficient IVD to follow up disease activity of autoimmune diseases: a challenge for theragnostics. http://www.biotec.tu-dresden.de/fileadmin/press/press-releases/12.06.20._Saechischer_Biotechnologietag.pdf

[Inv61] IL18: 32nd European Peptide Symposium, Athens (Greece), September 2-7 2012. September 7, 2012: Lectureinvited by the Chair Prof. George Kokotos. Title: The mimicry pathway from anti-glycopeptide antibodies to specific protein antigens of immune-mediated neurodegenerative/neuroregressive diseases: the case study of Rett syndrome.

[Inv62] IL19: 2nd Austrian Peptide Symposium, Vienna (Austria). November 29 2012.Invited by the Chairs Prof. Christian F.W. Becker and Dr. Christian Gruber. Title: Post-translationally modified peptides detecting autoantibodies as biomarkers of neurodegenerative diseases: A challenge for theragnostics of immune-mediated diseases.

[Inv63] S31: Département de Chimie, Faculté des arts et des sciences, Université de Montreal (Québec), Salle 1035, Pavillon J.-A. Bombardier. December 12, 2012. Seminar invited by Prof. William D. Lubell and Prof. Joelle Pelletier. Title: A “Chemical Reverse Approach” to Modulate Peptide Secondary Structures Inducing Specific and High Affinity Biological Recognition. http://www.calendrier.umontreal.ca/detail/155102

2013

[Inv64] S32: Karlsruhe Institute of Technology , Department of Molecular Biophysics at the Institute of Biological Interfaces, Karlsruhe (Germany).January 21, 2013. Seminar invited by Prof. Dr. Anne S. Ulrich. Title: Peptide secondary structures modulating biological recognition: a “chemical reverse approach”.

[Inv65] PL11: 22nd Polish Peptide Symposium, Kudowa Zdroj (Poland), September 1-5, 2013. September 4, 2013. Plenary Lecture invited by the Chairman Prof. Rafal Latajka. Title: Autoimmunity and Neurodegeneration: the Mimicry Pathway From Aberrant N-glucosylated Peptides to Specific Protein Antigens.

2014

[Inv66] IL20: Gordon Research Seminar (GRS): Chemistry & Biology of Peptides: Recent Advances in the Peptide Chemistry Toolbox, Ventura Beach Marriott, Ventura, CA (USA), February 22-23, 2014. February 22, 2014. Discussion leader invited by the Chairs Charles J. Bowerman and Neha Garg for the Session title: “Pushing the Boundaries of Peptide Methodology and Application”.https://www.grc.org/chemistry-and-biology-of-peptides-grs-conference/2014/

[Inv67] IL21: Hungarian Peptide Symposium, 28-30 May, 2014, Lake Balaton (Hungary). May 28, 2014: Invited by the Chair Prof. Gabor Mezo. Title: Post-translationally modified peptides to develop efficient IVDs to follow up disease activity: a challenge for theragnostics of autoimmune diseases.

[Inv68] KL2: 14^th Naples Workshop on Bioactive Peptides “The Renaissance era of Peptides in Drug Discovery”, Aula Magna Partenope, Centro Congressi “Federico II”,Napoli (Italy), 12-14 June 2014. June 13, 2014: Keynote Lecture su invito dei Chair Prof. G. Morelli, Dr. M. Saviano e Prof. Paolo Grieco. Title: From an N-glucopeptide synthetic probe to an hyper-glucosylated protein antigen: a bacterial infection triggering and antibody mediated form of multiple sclerosis?

[Inv69] IL22: First European Workshop on Tolerogenic Vaccination in Autoimmune Diseases, University of Piemonte Orientale “Amedeo Avogadro” Aula Magna, Via Solaroli 17, 28100 Novara (Italy). November 20, 2014. Invited by the Chairs Prof. Umberto Dianzani and Prof. John Matsoukas. Title: Glycopeptides and immune response.

2015

[Inv70] S33: Technische Universität München, Emil Erlenmeyer Forum 5, Freising, Weihenstephen (Germany). June 2, 2015. Invited by Prof. A. Kaporniotu. Title: A “Chemical Reverse Approach” to Modulate Peptide Secondary Structures Inducing Specific and High Affinity Biological Recognition.

[Inv71] IL23: International Joint Israel-Greek-Italian Neuroimmunology Meeting, Elounda, Crete (Greece), June 11-14, 2015. 13 June 2015. Invited by the Chairs Prof. Dimitrios Karussis. Title: From synthetic glycopeptides to the discovery of bacterial proteins cross-reacting with anti-N-glucosylation antibodies in Multiple Sclerosis.

[Inv72] PL12: 23rd Polish Peptide Symposium August 30 – September 3, 2015. Hotel Zacisze Piłsudskiego 97-215 Spała (Poland). September 1, 2015. Plenary Lecture invited by the Chair Prof. Beate Kolesinska. Title: Strategies for modulation of secondary structures to optimise biological recognition.

[Inv73] IL24: 15th International Conference on Microwave and High Frequency Heating AMPERE 2015, Carocow (Poland), September 14-17, 2015. September 16, 2015. Invited by the Chairman Dariusz Bogdal. Title: The challenge of MW-assisted solid-phase peptide synthesis: R&D of peptide-based diagnostics.

2016

[Inv74] IL25: Gordon Research Seminar (GRS): Chemistry & Biology of Peptides: Peptides and Petidomimetics: Inspired by Nature and Applied by Scientists, Ventura Beach Marriott, Ventura, CA (USA), February 20-21, 2016. February 20, 2016: Discussion Leader invited by the Chairs Neha Garg and Astrid Knuhtsen for the Session “Peptides in Infectious Diseases”.https://www.grc.org/chemistry-and-biology-of-peptides-grs-conference/2016/

[Inv75] S34: Department of Biology, Technische Universität Darmstadt (Germany). July 7, 2016.Invited by Prof. Maria Cristina Cardoso. Title: From an N-glucosylated peptide to a bacterial protein involved in triggering autoantibodies in Multiple Sclerosis and Rett Syndrome

[Inv76] S35: UMR CNRS BioCIS – Unité Mixte de Recherche CNRS BioCIS (Biomolécules: Conception, Isolement, Synthèse), Faculté de Pharmacie, Université Paris-Sud, Chatenay-Malabry (France). October 13, 2016. Invited by the Director Dr. Bruno Figadère. Title: Antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

[Inv77] PL13: Theo Murphy International Scientific Discussion meeting, The Royal Society “Self-assembled peptides: from nanostructure to bioactivity” Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ (UK), October 24-25, 2016. October 25, 2016. Plenary Lecture invited by the Chairs Prof. Dek Woolfson and Prof. Louise Serpell. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens. Tape record of the talk: http://downloads.royalsociety.org/events/2016/10/self-assembled-peptides/Papini.mp3

[Inv78] S36: IBB - Istituto CNR di Biostrutture e Bioimmagini, Sezione di Catania (Italy), December 6, 2016. Invited by the Director of IBB Dr. Marcello Mancini and the Director of the Unit of Catania Dr. Giuseppe Pappalardo. Title: Autoimmunity and neurodegeneration. The mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens, antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

2017

[Inv79] PL14: SECO 54 – 54th Edition of the « Semaine d’Etudes en Chimie Organique », May 7-13 2017, Saint Martin de Londres, Hérault (France). May 9, 2017: Plenary lecture su invito del Dr. Kévin Fauché a nome del Comitato organizzatore. Title : Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens.

[Inv80] PL15: 24th Polish Peptide Symposium on the occasion of the 50th anniversary of the first meeting of Polish scientists working in the field of peptides, Jastrzębia Góra, Gdańsk (Poland), September 3-7, 2017. September 5, 2017: Plenary lecture invited by the Chairperson Prof. Sylwia Rodziewicz-Motowidło for the “Session dedicated to the memory of Dr. K. Bankowski: Peptide and peptidomimetics synthesis”. Title: Cosmeceuticals behind the secret of youth: a peptide point view.

[Inv81] S37 I Lincei per una nuova didattica nella scuola a.s. 2017-2018. Polo di Firenze. Corso di Formazione in Scienze. Aula Strozzi, Via La Pira 4, Firenze, 12 Dicembre 2017, 15:00-18:00. Title: Nel Mondo dei Carboidrati: Struttura e nomenclatura dei carboidrati e delle biomolecole. Invited by the Coordinator Prof. V. Schettino.

2018

[Inv82] S38: Technische Universität München, Emil-Erlenmeyer-Forum 5, Freising-Weihenstephen, January 9, 2018. Invited by Prof. Dr. Aphrodite Kapurniotu. Title: Peptides in the pharmaceutical market: state-of-the art and perspectives.

[Inv83] S39: Center of Evolutionary Chemical Biology, Department of Chemistry & Nano Science Center, University of Copenhagen, January 11, 2018. Invited by Prof. Dr. Morten Meldal. Title: Antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

[Inv84] S40: Corso di specializzazione per attribuzione ECM “Endocrine Disrupting Chemicals and Developmental Origins of Health and Disease”, Reggio Emilia (Italy), 23 Febbraio 2018. Invited by the Chair Prof. Maria Street to moderate session IV: Nuovi supporti per la ricerca.

[Inv85] KL3: RiminiPeptides 2018: “Peptides and conjugates for tumor targeting, therapy and diagnosis:, June 16-18, 2018 Rimini (Italy). June 17, 2018. Keynote Lecture invited by the Chair Prof. Dr. Norbert Sewald. Title:Exotic side chain-to-side-chain cyclization modes in octreotide analogs for tumor pretargeting.

[Inv86] KL4: EuroChemistry Conference 2018 June 11-13, 2018 Rome, Italy. June 11, 2018. Keynote lecture invited by the Chair Dr. Steven J. Soldin. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific bacterial antigens.

[Inv87] S41: Wroclaw University of Technology, Zakład Technologii Organicznej i Farmaceutycznej Wydział Chemiczny (Poland), June 28, 2018. Invited by Prof. Dr. Rafal Latajka. Title: "Peptides and conjugates for tumor targeting, therapy and diagnosis: the wonderful world of click chemistry".

[Inv88] PL16: International Workshop & Summer School “Mass spectrometry in Medical Technology and Biotechnology” Int. MSc Course “Medizintechnik/ Medical Technology”, Rhein Main University, Rüsselsheim am Main (Germany), August 19-25, 2018. August 19, 2019: Plenary opening Lecture invited by Prof. Dr. Michael Przybylski. Title: “A chemical approach to identify peptide epitopes for high affinity antibodies in autoimmune diseases”.

[Inv89] IL26: EuroPEPTIDES 2018 part of Tides Europe: Peptide Discovery and Drug Development Strategies, Postillion Hotel Amsterdam, Paul Van Vlissingenstraat 8, NL – 1096 BK Amsterdam (NL), November 6-8, 2018. November 6, 2018. Invited by Dr. Waleed Danho. Title: “New Modalities and peptide drug development strategies”.

[Inv90] IL27: 10th International Peptide Symposium, ROHM Theatre Kyoto and Miyako Messe (Japan), December 3-7, 2018. December6, 2018. Invited by the Chair Prof. Shiroh Futaki. Title: “Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae”.

2019

[Inv91] S42: L. LEKARSKA FAKULTA, Univerzita Karlova, Large meeting room of Dean’s Office Building, Praha (Tchek Republic), March 19, 2019. Invited by Prof. Aleksi Šedo, Dr. Sc., Dean of the First Faculty of Medicine. Title: Glycopeptides as immunological probes for the characterization of autoantibodies, biomarkers of Multiple Sclerosis.

[Inv92] S43: CoffeTalk@ISOF: Extended Edition. ISOF12- CNR Area della Ricerca di Bologna - Ed. 12; Meeting Room (1st Floor), Via P. Gobetti 101, 40129 Bologna (Italy), April 16, 2019. Invited by Dr. Paolo Dambruoso. Title: A chemical approach to identify peptide epitopes for high affinity antibodies in autoimmune diseases.

[Inv93] S44: 5th Workshop of the Joint Doctoral Program in Chemistry (Università degli Studi di Trieste e Università Cà Foscari di Venezia), Room Giorgio Padoan, San Sebastiano, Venezia, June 26-28, 2019. June 28, 2019. Invited by the Coordinator of the PhD School Prof. Barbara Milani. Title: A Chemical Reverse Approach to develop efficient and reliable peptide-based diagnostics for immune-mediated diseases.

[Inv94] S45: Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Czech Republic. Title: A « Chemical Reverse Approach » to develop efficient and reliable peptide-based drugs and diagnostics for immune-mediated diseases. Invited by Prof. Dr. Magdalena Chottova-Dvorakova

[Inv95] PL17: 25th Polish Peptide Symposium, Wojanów (Poland), September, 8-12, 2019. September 9, 2019: Plenary lecture invited by the Chair Prof. Justyna Brasun. Title: The Chicken or Egg dilemma: are antibodies to aberrantly modified conformational peptide epitopes in autoimmunity reminiscent of early infections?

[Inv96] S46: Colloquium of the Department of Bioscience and Biotechnology Konkuk University Seoul 05029 (Korea) October 14, 2019 – 3:00 pm. Title: Are antibodies to aberrantly modified conformational peptide epitopes in autoimmunity reminiscent of early infections?

[Inv97] PL18: Recent Advances in Peptide Research, Joint International Peptide Symposium Korean Protein Peptide Society & SKKU College of Pharmacy. Sungkyunkwan University, Suwon (South-Korea), October 15, 2019. Title: From a synthetic N-glucosylated peptide probe to an hyper-glucosylated adhesin protein antigen: a bacterial infection triggering an antibody mediated form of Multiple Sclerosis?

[Inv98] IL28: 124th Korean Chemical Society National Meeting. Session: Peptides and Biological Chemistry, Changwon (South Korea), October 17-18, 2019. Invited Lecture by the Secretary general of the Korean Chemical Society (KCS), Division of Biological Chemistry on behalf of the Organising Committee Dr. Hyun-Suk Lim, by the President of the Korean Peptide Society Prof. Yangmee Kim and the President of the KCS Division of Biological Chemistry Prof. Sang Jeon Sung. Title: Strategies for modulation of secondary structures to optimise biological recognition.

[Inv99] S47: Visiting Professor Master 2, Université de Rouen Haute-Normandie, November 20-22, 2019. Course title : Peptide drugs: the potentiality becoming actuality. Invited by the Director of the Course Prof. P.-Y. Renard.

[Inv97] AL3: Council forHigher Education (Israel). Rita Levi Montalcini Prize 2019 for Israel-Italy Scientific Cooperation (Prof. Nir Quit, Bar-Ilan University, Dr. Mattan Hurevich, Institute of Chemistry, Hebrew University of Jerusalem, Dr. Rina Aharoni, Weizmann Institute of Sciences) The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel, December 23, 2019, 2 pm. Title: The Chicken or Egg dilemma: Are antibodies to aberrantly modified conformational peptide epitopes in autoimmunity reminiscent of early infections?

2020

[Inv98] PL19: 17th Iberian Peptide Meeting (17^th EPI), Auditorium of the Rocasolano Institute of Physical Chemistry (IQFR), Consejo Superior de Investigaciones Cientificas (CSIC), Madrid (Spain), February 5-7, 2020. February 5, 2020. Plenary Lecture invited by the Chairs Rosario González-Muñiz, Mª Angeles Jiménez and María José Camarasa. Title: Strategies for modulation of peptide secondary structures to optimise biological recognition. http://epi2020.iqfr.csic.es/

[Inv99] IL29: 85th Annual Meeting of the Israel Chemical Society, W1: Chemical Biology (Teddy A). International Convention Center ICC (Binyanei Hauma), Jerusalem (Israel), February 18-19, 2020. February 19, 2020 – 11:50-12:20. Invited Lectureby the Chairs Shlomo Yitzchaik and Lioz Etgar. Title: From a synthetic N-glucosylated peptide probe to an hyper-glucosylated adhesin protein antigen: a bacterial infection triggering an antibody mediated form of multiple sclerosis?

2021

[Inv100] IL30: Latest Development in Peptide Synthesis. Academic Guest Speaker. Title: The challenge to design fully automated solid-phase MW-assisted cGMP ready processes of peptide production as active pharmaceutical ingredients. CEM Webinar 10^th March 2021 9:15am-3:00pm. https://www.cemmicrowave.co.uk/copy-of-peptide-synthesis-webinar-march-2021---speakers. https://vimeo.com/cemmicrowave/peptidewebinar2021

[Inv101] PL20: 2021 Boulder Peptide Symposium, Peptide Vaccines Virtual Mini-Symposium, St. Julien Hotel & Spa in Boulder, Colorado, June 11, 2021, 12:00 Invited Lecture by Dr. John Philip Mayer, University of Colorado Boulder and Dr. Matthew Duffy, Title: Aberrantly modified conformational peptide epitopes, specific for antibodies biomarkers of immune-mediated diseases, can be reminiscent of an early infection. The Chicken or Egg dilemma? https://boulderpeptide.org/

[Inv102] S48: Bussole per i tempi nuovi. Fondazione CR Firenze in collaborazione con la Fondazione Parchi Monumentali Bardini e Peyron. 10 Giugno 2021, Villa Bardini, Firenze (Italy). Titolo : Nuove molecole per nuove sfide: proteine e peptidi per una nuova medicina. Invited by the Chair Prof. Luca Rosi.

2022

[Inv103] IL31: GIOCONDA’S SMILE AWARD Acquario di Roma, 20 Maggio 2022. Title: Plastica e autismo: Il chimico alla ricerca delle molecole che interferiscono con la salute del bambino. Invited by the organising committee.

[Inv104] S49 CEM Workshop, 36th European Peptide Symposium and 12^th International Peptide Symposium, Sitges, Barcelona, Thursday September 1, 2022, 13:30 p.m. Title: Optimisation of Safe Processes from Bench to Pilot cGMP Production of Peptide Active Pharmaceutical Ingredients: The Challenge of Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer. Invited by CEM.

[Inv105] IL32: 36th European Peptide Symposium and 12^th International Peptide Symposium, Sitges, Barcelona, Wednesday August 31, 2022, 19:00-19:30. Title: The challenge of epitope presentation for efficient antibody recognition: a lesson from autoimmune diseases for a more effective management of emerging infectious diseases. I11. Invited by the Chair: Dr. M. Teixeido.

[Inv106] S50: XL-CHEM Graduate School of Research Autumn School 2022, Friday September 9, 2022 – 10:15-12:15. Amphi Poirier, MSA - Normandie Université. Title: The challenge of biological function optimisation through side-chain to side-chain macrocyclisation fine tuning of peptide secondary structures. Invited by Prof. J.Y Renard.

[Inv107] IL33: Convegno Internazionale 4° INCONTRO: AMBIENTE, DIABETE ED ENDOCRINOPATIE IN PEDIATRIA, NH Parma, Via P. Borsellino 31, 22-23 Settembre 2022. Title: IL PROGETTO EUROPEO LIFE-MILCH: NUOVI DATI UN ANNO DOPO, Invited by the Chair Prof. Maria Street.

[Inv108] IL34: 18th International Workshop on Neonatology and Pediatrics. From womb to adulthood. T HOTEL, Cagliari (Italy), 19th – 22nd October 2022. Title: Endocrine Disrupters in Milk. Quantitative analysis of phthalates, bisphenols, parabens, pyrethroids, PAHs, polar pesticides and metals in baby bottles, infant formula, and breast milk to define their role as EDCs in the Life MILCH project. Invited by the President of the Symposium Vassilios Fanos                   

[Inv109] S51: Webinar Xtalks. Gyros Protein Technologies, Friday October 28, 2022 – 16:00 pm CEST. Title: Obtaining Complex Peptides Thanks to Efficient Technologies is No Longer a Dream: Successful Stories of Difficult Syntheses,

[Inv110] S52: Associazione Amici del Liceo Scientifico «Leonardo da Vinci» di Firenze  29 Novembre 2022. Liceo Scientifico « Leonardo da Vinci », Firenze. Title: Una lezione dalla natura per combattere virus e batteri: peptidi e proteine

2023

[Inv111] IL35: Terza edizione  Rotary EXPO PLASTIC FREE  NELL’AMBIENTE. Roma, 31 Marzo 2023. Title: Salute e inquinamento da microplastiche: una ricerca Universitaria sull’aumento delle nascite con patologie di autismo. Invited by the President of the Rotary Club Roma.

[Inv112] S53: EUniWell SFC5 Kick-off Meeting. University of Cologne. Wednesday June 7, 2023 14:00-15:30. Title: Technology Transfer of Peptides for the Well-being Economy: TTPep - Peptides for Well-being. Invited by Prof. Dr. Ines Neundorf

[Inv113] PL21: 10th International Peptide Conference, Bulgarian Peptide Society, Varna, Bulgaria. Session 1, September 1, 2023. Title: From peptide-based drugs and diagnostics to cosmetics to inspire next Generation EU Researchers to transfer academic results into the market. Invited by Prof. Pamela Papajnova.

[Inv114] S54: EUniWell SFC5 Workshop: Introduction Research Incubator Programme 2023, Peptides as natural products for well-being. University of Birmingham, Wednesday September 26, 2023 15:00-18:00. Title: Technology Transfer of Peptides for the Well-being Economy: TTPep - Peptides for Well-being. Invited by Dr. Liam Grover

[Inv115] IL36: 19th International Workshop on Neonatology and Pediatrics, FROM WOMB TO AGING, FROM MEDICAL HISTORY TO ARTIFICIAL INTELLIGENCE. 18th-21st October 2023 | T Hotel, Cagliari. Title: The first comprehensive diagnostic profile of specific metabolites of EDCs phthalates, bisphenols, parabens, pyrethroids, PAHs, and polar pesticides in mother and child dyads News from the LIFE MILCH project. Invited by the Chair Prof. V. Fanos. Lecture 40.  Journal of Pediatric and Neonatal Individualized Medicine 2022;11(2):e110243, p 40-41. doi: 10.7363/110243 Published online: 2022 Oct 18. 

[Inv116] IL37: 60th Anniversary of Japanese Peptide Symposium: Development of Peptide Science. November 9, 2023 – Biwako Hall, Center for the Performing Arts, Shiga 15-1 Uchidehama, Otsu-shi, Shiga. Session 7 November 9, 2023 - 11:10-11:35 a.m. Title: From Serpin A1 to KP1 protecting dermal collagen from degradation: the story of a peptide-based cosmeceutical into the market and beyond. Invited by the Chairs: Prof. and Prof.

[Inv117] IL38: International Mini-Symposium on Peptide Design and Functional Extension: A Satellite Symposium of the 60th Japanese Peptide Symposium. Saturday, November 11th, 2023, Seminar Room 4 and 5, Uji Obaku Plaza, Kyoto University. Title: From peptides to peptidomimetics and the challenge of industrial applications. Invited by the Chair Prof Shiroh Futaki.

[Inv118] S55: Osaka Municipality University, November 13, 2023, Title: A peptide-based approach to fight SARS-Cov-2: from vaccines to antivirals. Invited by Prof. Ikuo Fujii

[Inv119]IL39: V Incontro Ambiente, Diabete ed Endocrinopatie in Pediatria. 16-17 Novembre 2023 | NH Hotel, Parma (Italy). Title: Gli Interferenti endocrini nelle diadi madre-bambino. Invited by the Chair Prof. M. Street.

2024

[Inv120] S56: Proteinwissenschaftliches Kolloquium Weihenstephan and SFB1035, Technische Universität München (TUM), School of Life Sciences, Emil-Erlenmeyer-Forum, Freising, Germany. January 19, 2024  - 11:15 a.m. Title: A peptide-based approach to fight SARS-Cov-2: from vaccines to antivirals. Invited by Prof. Dr. Aphrodite Kapurniotu

[Inv121] S57 PurePep Webinar, Gyros Protein Technologies, Wednesday May 8, 2024 – 4:00 pm CET. Title: Cutting through the noise of green peptide chemistry: The challenge for safe manufacturing processes not only of API but also cosmetic quality grade. Invited by Dr. D. Sarma, MesaLab.

[Inv122] AL4: 20st  Annual Meeting of The Medicinal Chemistry Section of the Israel Chemical Society (MCS-ICS), The David Lopatie Conference Centre, Weizmann Institute of Science, July 18, 2024: 2024 Award for Excellence in Medicinal Chemistry in Memory of Barry Cohen attributed to A.M. Papini for her immense contributions to peptide science and chemical immunology (thanks to an endowment fund donated by Teva Pharmaceutical Industries in memory of Mr. Abraham (Barry) Cohen, a prominent member of Teva's Board of Directors that passed away in 2012). Title: From chemical immunology to medicinal chemistry: the power of peptides to elucidate the mystery of molecular mimicry.

[Inv123] S58: Presentations by the Scientiifc Advisory Board Members, Instituto de Quimica Medica-CSIC, C/Juan de la Cierva 3, Madrid (Spain), September 17, 2024 – 10:00-12:00. Title: From chemical immunology to medicinal chemistry: the power of peptides to elucidate the mystery of molecular mimicry. Invited by the Director Dr. M. Jesus Perez de Vega.

[Inv124] IL40: Meeting “Sustainable development in the Tuscan territory: the contribution of the University and the professions”, Auditorium Centro Tecnico Federale Coverciano, Firenze (Italy), 8 November 2024. Title: The new perspectives of Sustainable Chemistry. Invited by the Chair. Prof. Laura Bini.

[Inv125] IL41: VI Incontro Ambiente, Diabete ed Endocrinopatie in Pediatria. 29-30 Novembre 2024 | NH Hotel, Parma (Italy). Title: Gli Interferenti Endocrini: dall’Ambiente al Latte Materno fino alle Urine del Neonato. Invited by the Chair Prof. M. Street.

[Inv126] S59: Seminar of the Institute of Chemistry for Life and Health Sciences (i-CLeHS), UMR CNRS 8060, ENSCP-Chimie ParisTech (Paris, France), December 17, 2024. Title: From peptide-based drugs and diagnostics to cosmectics to inspire next generation EU researchers to transfer academic results into the market. Invited by the Director Prof. Dr. Carlo Adamo.

2025

[Inv127] IL42: Chemical Biology Mini-Symposium. New Chemistry Unit and School of Advanced Materials, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India. Lecture 25th February 2025. Title: The challenge of molecular mimicry triggering the immune system: structure-based designed linear and conformational peptide epitopes to trap antibody biomarkers.  Invited by the Chair Prof. T. Govindaraju

[Inv128] IL43: 10^th Indian Peptide Symposium. Iiser Pune (India) February 26-28, 2025. Lecture 27^th February 2025, 11:10-11:35 am. Title: The challenge of biological function optimization fine tuning peptide secondary structures by side-chain to side-chain macrocyclization. Invited by the Chair Prof. H N Gopi

[Inv129] S60: Corso di laurea triennale in Chimica e Chimica Industriale, Dipartimento di Chimica, Università degli Studi di Padova, Via Marzolo, Padova, Italy. March 19, 2025 - 16:30-18:00. Title: Peptidi in Terapeutica e Diagnostica: il ruolo del "peptide bioorganic chemist". Invited by Prof. Marta De Zotti.

[Inv129] S61: Proteinwissenschaftliches Kolloquium Weihenstephan and SFB1035, Technische Universität München (TUM), School of Life Sciences, Emil-Erlenmeyer-Forum, Freising, Germany. May 8, 2025  - 14:00-16:00. Title: Peptide Power: Harnessing Lessons from SARS-CoV-2 to Revolutionize Antiviral and Antibacterial drugs. Invited by Prof. Dr. Aphrodite Kapurniotu

[Inv130] PL22: Peptide Chemistry Day, University of Zagreb, 21st May 2025 - 9:15-10:00. Title: From Chemical immunology to Medicinal Chemistry: the power of peptides to elucidate the mystery of molecular mimicry. Invited by the Chair Prof. Ruza Frkanec.

[Inv131] IL44: 29th American Peptide Symposium & 15th International Peptide Symposium, June 15-19, 2025, Sheraton San Diego Hotel & Marina in San Diego, CA (USA). L24, 8:45-9:10, June 17, 2025. Title: Advancing Sustainable Peptide Synthesis: Green Strategies for Scalable and Efficient Automatised Solid-Phase Manufacturing. Invited by the Chairs: Dr. Eileen J. Kennedy, Dr. Jean Chmielewski and Dr. Wendy Hartsock

[Inv132] KL5: French Italian Joint Peptide Meeting: GFPP24 and ItPS5. June 22-26, 2025, Aussois (France). Keynote speaker PL6, 10:40-11:30, June 24,  2025. Title: From peptide-based drugs and diagnostics to cosmetics to inspire next generation EU researchers to Transfer academic results into the market. Invited by the Organising Committee.

[Inv133] KL6: EUniWell First CAS Symposium Innovation in Well-Being for SDGs Achievement. Santiago de Compostela 24-26 June, 2025. Title: Keynote by Anna Maria Papini, UNIFI EUniWell Champion: “Peptides 4 WellBeing”. June 25, 2025, 15:00-18:00. Invited by EUniWell University alliance.

[Inv134] IL45: EPSC 2025:3 The European Peptide Synthesis Conference of 2025. Sheraton Porto Hotel, Porto, Portugal, 25-27^th August 2025. Title: Advancing Sustainable Peptide Synthesis: Green Strategies for Scalable and Efficient Automatised Solid-Phase Manufacturing. August 25, 2025 15:00-15:30. Invited by the Event Chair Elisabetta Bianchi, Senior Director, Peptide Chemistry Curium SpA.

[Inv135] AL5: Keynote lecture on the occasion of the attribution of the Medal of the Polish Chemical Society during the 67th Scientific Meeting of the Polish Chemical Society. Wednesday, September 24, 11:40 AM. Title: From chemical immunology to medicinal chemistry: the power of peptides to elucidate the mystery of molecular mimicry. Invited and awarded by the Board of the Polish Chemical Society

Invited Lectures aimed to technology transfer

(Period 2004-2025)

[ILTT1] Simposio “Direzioni future nella sclerosi multipla”, Facoltà di Medicina e Chirurgia, Università di Firenze, Dipartimento di Scienze Neurologiche e Psichiatriche, Firenze, (Italy), Aula Magna della Facoltà di Medicina. 6 April 2004. Invitedspeaker by Prof. S. Sorbi. Title: CSF114(Glc): un glicopeptide sintetico, marker innovativo di sclerosi multipla mediata da autoanticorpi.

[ILTT2] i-techpartner Academy Italy, Research leaders and entrepreneurs assess collaborative innovation, APRE Europe, Rome (Italy). 27 November, 2007. Invited by APRE as Chief of the Scientific Committee of Toscana Biomarkers Srl (Siena) and research leader of the universities involved in funded start-ups. Title: Modified peptides as diagnostic tools for autoimmune disease: a chemical reverse approach.

[ILTT3] 2nd TLS Investment Advisory Panel Meeting, Hotel Garden, Via Custoza 2, Siena (Italy), Fondazione Toscana Life Sciences. July 13, 2007.Invited by Francesco Maria Senatore, Business development TLS. Title: Optimised synthetic strategies to develop an efficient diagnostic/prognostic test for Multiple Sclerosis.

[ILTT4] “Peptide Users Group”, Spring Symposium, Mimotopes – Genzyme Pharmaceuticals, Melbourne (Australia). October 30, 2007.Invited by Mimotopes - The Peptide Company. Title: Optimised synthetic strategies to develop an efficient diagnostic/prognostic test for Multiple Sclerosis.

[ILTT5] BioInItaly 2008, Milan Chamber of Commerce Special Agency for Innovation, Affari ai Giureconsulti, Milano (Italy), March 31-Apri1, 2008. April 1, 2008. Invited by the organising committee. Title: Toscana Biomarkers

[ILTT6] BioInItaly in partnership with innovhub, Milan Chamber of Commerce Special Agency for Innovation, Affari ai Giureconsulti, Milano (Italy), May 4-5, 2009. May 5, 2009. Invitedspeakerby Dr. Roberto Gradnik, President of Assobiotech (Italian Association for the Development of Biotechnology). Title: The Start-up Toscana Biomarkers.

[ILTT7] Conseil Général du Val d’Oise, 2 Avenue du Parc, 95000 Cergy-Pontoise (France), July 7, 2009. InvitedbyDr. Jean-Francois Benon, General Manager of CEEVO, (Comité d’expansion économique du Val d’Oise). Title: Molecular Detection for Life Sciences (MoDeLS). A project under the Seventh Framework Programme – Regions of Knowledge Initiative.

[ILTT8] Region of Osaka (Japan). Mission Economique du Val d’Oise. November 10, 2009. Invited by the Region of Osaka. Title: Molecular Detection for Life Sciences MOD&LS: A Project under the 7^th Framework Programme-Regions of Knowledge Initiative.

[ILTT9] State University of Osaka (Japan). November 13, 2009. Invited by the Region of Osaka. Title: Molecular Detection for Life Sciences: An European Project coordinated by the Conseil Général du Val d’Oise.

[ILTT10] Ricerca Impresa, Polo Scientifico di Sesto Fiorentino, Università di Firenze (Italy). December 3, 2009. Title:Molecular Detection for Life Sciences (MoDeLS): An European Project coordinated by CGVO – Ile de France.

[ILTT11] Conseil Régional de Bourgogne, 17, boulevard de la Trémouille CS, Dijon (France). December 9, 2009. Invited by Conseil Régional de Bourgogne. Title: Molecular Detection for Life Sciences (MoDeLS): An Innovative Management Model of European Projects.

[ILTT12] TLS Work in Progress, Centro Ricerche Novartis, Siena (Italy). December 11, 2009. Invited by the General Manager of Toscana Life Sciences Dr. G. Carganico. Title: Toscana Biomarkers S.r.l. R&D start-up company. Start-up Toscana Biomarkers.

[ILTT13] Presentation to Cosmetic Valley in Neuville Université (France).February 24, 2010. Invited by the Directeur Général and Founder of Cosmetic Valley Jean-Luc Ansel. Title: European Leonardo Institute of Technology@UCP. An Infrastructure to favour Innovation in Cosmetics towards Cosmeceutics.

[ILTT14] Hybrigenics, Paris (France). March 10, 2010. Invited by the Director of Industrial Operation & Technology Development Jean-Christophe Rain, Dr. Sci.Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics".

[ILTT15] CGVO Semaine de la Recherche et de l’Innovation Cergy-Pontoise (France).May 3, 2010. Invited by the Managing Director of Val d’Oise Economic Expansion Committee Dr. Jean-Francois Benon.Title: Molecular Detection for Life Sciences. An Institute of Technology@UCP. An Infrastructure to favour Innovation in Diagnostics: an European Model.

[ILTT16] Roche Partnering GEM EventResearch and Technology Team. Hotel Lutetia, 45 Blvd. Raspail, 75005 Paris (France). June 23, 2010. Invited by the Manager Global Business Development Dr. Imma Barrera and RP DBA Leader Metabolism Dr. Andrew Sleight. Title: Toscana Biomarkers S.r.l. R&D start-up company.

[ILTT17] 5th EU-China Business & Technology Cooperation Fair, organised by the EU Project Innovation Centre – EUPIC, and Chengdu Hi-Tech Zone Management Committee, Chengdu, Sichuan (China), 16-21 October 2010.Speech from the experts October 18, 2010. Guest speakerinvited by Segree Dai, CEO of EUPIC. Title: Molecular Diagnostics for Life Sciences (MoDeLS) An European Infrastructure based on a Technology Platform Network to favour R&D in SMEs

[ILTT18] China – Italy Regional Cooperation Forum on Technology and Innovation, Fortezza da Basso, Firenze (Italy), 10-12 November 2010. November 11, 2010. Invitedspeaker for the session “Life Sciences e industria della salute” by Assobiotec and Toscana Life Sciences as a successful example of SME. Title: Toscana Biomarkers: the proof-of-concept of an innovative approach to molecular diagnostics.

[ILTT19] F. Hoffman La Roche, Basel (Switzerland). February 1, 2011. Invited by the Director of Peptide Discovery. Title: Toscana Biomarkers S.r.l. R&D start-up company.

[ILTT20] Meeting UCP & 3M Science, Neuville Université. September 1, 2011. Invitedspeaker by 3M Science.Title: Molecular Diagnostics for Life Sciences (MoDeLS). An European Infrastructure based on a Technology Platform Network to favour R&D in SMEs.

[ILTT21] IPSEN INNOVATION – ZI de Courtaboeuf 5, Av. Du Canada 91940 Les Ulis (France). January 18, 2012. Invited by Dr. Christophe Lanco, Sr Scientist - Compounds Discovery. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[ILTT22] EuroPEPTIDES 2013, Clarion Congress Hotel Prague (Czech Republic), November 13-14, 2013. November 13, 2013. Invited as speaker at the forefront of peptide development for the “Session on peptide diagnostics and biomarkers” by the Chair Dr. Waleed Danho on behalf di INFORMA. Title: Optimised Synthetic Strategies to Post-Translationally Modified Peptides as Reliable Diagnostics of Immune-Mediated Diseases.

[ILTT23] Connexions R&D 2013: Rencontrez les acteurs de la recherche en cosmétique. Les Turbulences, Frac Centre, Orléans (France). December 10, 2013. Invited by the President J.-L. Ansel on behalf of the scientific committee of Cosmetic Valley France. Title: Peptides et applications cosmétiques.

[ILTT24]1ère Edition des rencontres interdisciplinaires «Chimie-Biologie». SATT idfinnov, Cité Internationale Universitaire – Maison de Norvège, Paris (France). March 18, 2014. Invited by the scientific Committee of idfinnov. Title: « Projet PepKit » Mise en place et développement d’une approche de « chimie inverse » à l’Université de Cergy-Pontoise et création de la plateforme PeptLab@UCP ».

[ILTT25] Conférence Inter-professionnelle SUP’BIOTECH.Dermo-Cosmétologie : les enjeux de la R&D, Paris (France). February 10, 2015. Invited speaker by the scientific Committee. Title: Peptides et applications cosmétiques avec la présentation des plateformes de recherche sur les peptides (Université de Cergy-Pontoise).

[ILTT26] COMET 2015, 8 & 9 June 2015, Cergy-Pontoise (Val d’Oise, France). Title : AN IN VITRO TECHNIQUE FOR BIOLOGICAL SCREENING OF COLLAGEN TURNOVER MODULATING PEPTIDES AS ANTI-AGING.

[ILTT27] F.I.S.Fabbrica Italiana Sintetici, Montecchio Maggiore, Vicenza (Italy), 11 november 2016, Title: Il Laboratorio PeptLab di Firenze: un lungo viaggio nel mare tempestoso della chimica organica dei peptidi. Invited by Dr. Marco Galvagni, Head of R&D.

[ILTT28] Peptide Therapeutics Forum, BASEL LIFE, Congress Centre Basel (Switzerland), September, 10-11, 2019. September 11, 2019. Invited lecture by the Chairs Dr. Thomas Vorherr (Novartis Pharma AG, Basel, CH) and Roderich Suessmuth (Technical University of Berlin, Germany). Title: Exotic side chain-to-side-chain cyclization modes in octreotide analogs for tumor pretargeting. https://www.basellife.org/2019/basel-life-structure/innovation-forums/scientific-programme/peptide-therapeutics.html

[ILTT29] IOPC 2019 - International Oligonucleotides and Peptides Conference, Ramada Plaza Hotel, Milano (Italy), September 17-18, 2019. September 18, 2019. Invited by TeknoScienze as Member of the Scientific Committee, Chair of the Workshop on Delivery and Speaker. Title: Specific Glycosylation Techniques for Efficient Protein Therapeutics. https://www.iopc-tks.com/committee/

[ILTT30] UniFi@ARTES 4.0: Industry 4.0 Competence Centre on Advanced Robotics and enabling digital Technologies & Systems 4.0. Firenze (Italy) 22-23 Giugno 2021. Invited by University of Florence. Title: I peptidi: una lezione dalla natura per sviluppare molecole sostenibili d’interesse dell’industria cosmeceutica, nutraceutica, diagnostica, farmaceutica, dei materiali e molto altro.

Chair of scientific sessions in Symposia

Monday September 1, 2008 (16:00-17:20):  Chair of the Session 04 “Libraries and peptidomimetic applications”, 30th European Peptide Symposium, Helsinki (Finland), invited by the Chair Dr. H. Lankinen.

Wednesday October 28, 2009 (9:00-13:15): Chair of the Session III, Barcelona BioMed Confreences. Peptide engineering: therapeutic peptides, Barcelona (Spain), invited by the Chairs Prof. E. Giralt and Prof. C. Toniolo.

Monday September 6, 2010 (10:40-12:30):  Chair of the Session S2 “Synthetic Chemistry of amino acids and peptides”, 31st European Peptide Symposium, Copenhagen, invited by the Chair Prof. M. Meldal.

Thursday July 29, 2010 (15:20-16:20): Chair of the Session B, 24th International Symposium on the Organic Chemistry of Sulfur – ISOCS-24, Florence (Italy), invited by the Chair Prof. A. Degl’Innocenti.

Sunday June 10, 2012 (9:00-11:00): Chair of the Session VIII “Peptide drug design”, 13th Naples Workshop on Bioactive Peptides, Napoli (Italy), invited by the Chair Prof. G. Morelli.

Thursday September 6, 2012 (11:00-12:30): Chair of the 16th Session, 32th European Peptide Symposium, Athens (Greece), invited by the Chair Prof. G. Kokotos.

Wednesday September 4, 2013 (15:00-16:55): Chair of the Sessione “Enzymes substrates and inhibitors II”, 22nd Polish Peptide Symposium, Kudowa Zdroj (Poland), invited by the Chair Prof. R. Latajka.

Friday June 13, 2014 (16:40-18:20): Chair of the Session IB “Antimicrobial Peptides”, 14th Naples Workshop on Bioactive Peptides, Napoli (Italy), invited by the Chair Prof. G. Morelli.

Monday September 1, 2014 (14:00-16:40): Chair of the Session 3, 33rd European Peptide Symposium, Sofia (Bulgaria), invited by the Chair Prof. L. Vezenkov.

Wednesday September 2, 2015 (9:00-10:40): Chair of the Session “Peptides/Peptidomimetics for Medicine II”, 23rd Polish Peptide Symposium, Spala 2015 (Poland), invited by the Chair Prof. B. Kolesinska.

Saturday October 3, 2015 (8:30-13:30): Moderatore della I sessione “Chimica, cibo, acqua potabile e sicurezza alimentare”, XVII Congresso Nazionale dei Chimici, Milano (Italy), invited by the scientific coordinator Dr. E. Miriani.

Thursday September 8, 2016 (8:30-10:30): Chair of the Session “Imaging and modulation of enzymes and receptors: Receptor Modulation”, 34th European Peptide Symposium-8th International Peptide Symposium, Leipzig (Germany), invited by the Chair Prof. A. Beck-Sickinger.

Friday December 7, 2018 (14:50-16:20): Chair of the Session 14 “Peptides Today and the Future”, 10th International Peptide Symposium, Kyoto (Japan), invited by the Chair Prof. S. Futaki.

Thursday September 1, 2022 (18:00-20:00): Chair of the Session 12 “Bioactive peptides (antimicrobial, cancer, metabolism, neuropeptides, vaccines, etc.) (C) Miscellaneous”, 36th European Peptide Symposium and 12^th International Peptide Symposium, Sitges, Barcelona, invited by the Chair Dr. M. Teixeido.

Peptide organic chemistry

Development of innovative synthetic solid-phase technologies by sustainable strategies. Microwave assisted peptide and organic synthesis. Bioorganic chemistry of biomolecules: i.e., peptides and proteins. Synthetic & semi-synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (i.e., constrained amino acids, glycosyl and lipophilic amino acids, etc.). Peptidomimetics for the development of therapeutic treatments (i.e., cyclisation via click chemistry). Coupling reagents for peptide chemistry (amide and ester bond formation).

Molecular mechanisms of immune-mediated diseases

This project is performed in cooperation with clinicians supporting specimen and clinics of patients. An innovative "Chemical Reverse Approach" has been developed in PeptLab to characterise immune mediated diseases by circulating antibodies and/or metabolites in biological fluids: neurodegenerative and neurodevelopment diseases, i.e. Multiple Sclerosis, Optical Neuromyelitis, Myelin-Oligodendrocyte Associated Diseases, Rett Syndrome, Autistic Spectrum Disorders; Rheumatoid Arthritis; Gluten disease;  Primary Biliary Cyrrhosis. Cross-linked peptides, glycoconjugates and all kind of modified peptides (i.e. MAP) and other biomolecules are used as diagnostic, prognostic, and theragnostic tools to follow up disease activity in humans and setting up animal models. For the diagnosis and therapy of autoimmune diseases we investigate the role of co- or post-translational modifications of proteins and peptides (native versus aberrant) by immunochemical studies. The development of innovative diagnostic/prognostic tools by characterisation of biomarkers of disease activity is performed in the context of a strong technology transfer activities sponsored by the Regione Toscana (in cooperation with new start up and spin-off companies, i.e., EspiKem and Apotech). The fundamental research of this project is performed thanks to ANR and Fondation Pierre Gilles de Gennes in cooperation with the Ecole Normale Superieure in Paris.

She established and supervised the scientific activities of PeptFarm in the MOD&LS lab funded by the Regione Toscana and located at RISE b, Polo Scientifico of Sesto Fiorentino (https://www.unifi.it/upload/sub/csavri/rise_scheda_laboratori.pdf) a joined laboratory between PeptLab and the Industry Fabbrica Italiana Sintetici, F.I.S. SpA to develop large-scale protocols for the GMP synthesis of peptide-based active pharmaceutical ingredients.

Synthetic biology. Production of proteins specifically glycosylated, such as glucosylated adhesin protein from Haemophilus influenzae. Expression of cell-surface adhesins including N-Glc, to establish a connection between H. influenzae infection and autoimmune diseases, such as Multiple Sclerosis. We exploited the biosynthetic machinery from the opportunistic pathogen H. influenzae (and the homologous enzymes from A. pleuropneumoniae) to produce a unique set of defined glucosylated adhesin proteins to detect specific and high affinity antibodies.

Industrial applications

In vitro Diagnostics and peptide biomarkers. Autoimmune diseases. Molecular mechanisms of immune-mediated autoimmune diseases. Cross-reaction with infectious diseases. Glycoconjugates as diagnostic and prognostic tools for human, animal, and plant diseases. Diagnosis and therapy of autoimmune diseases: role of co- or post-translational modifications of myelin proteins and peptides for immunological studies on multiple sclerosis for the development of diagnostic/prognostic tools, innovative immunotherapies and characterisation of biomarkers of disease activity. Apheresis technologies. In vivo Diagnostics and imaging techniques. DOTA peptide analogues for cancer pre-targeting diagnosis & therapy. FIV peptides for the development of an anti-retroviral therapy for felines. Cultural heritage. Peptide-based immunoassays for characterization of glues, in particular collagen. Peptide Nutraceuticals and cosmeceutics. Spiruline. Fish feed. Peptides involved in collagen turnover. Development of processes for large scale solid-phase peptide synthesis. GMP production of active peptides as pharmaceutical ingredients. MW-technology. Peptide materials.

Who is interested to follow one of my lessons in Bioorganic Chemistry please copy this link into your browser

https://cloud.cla.unifi.it/owncloud/index.php/s/BKTPrYW6nS3SFTD

Chi fosse interessato a effettuare un'esperienza all'estero nell'ambito del suo ciclo di studi o anche successivamente, offro supporto in qualità di delegato per il programma Erasmus (LLP e Placement) per la Chimica e in qualità di delegato del Corso di laurea in Chimica per l'organizzazione di tirocini curriculari e extra-curriculari.

Contattemi via e-mail: annamaria.papini@unifi.it

Short Biography of Prof. Anna Maria Papini, PhD (www.peptlab.unifi.it)

Director of the Interdepartmental Research Unit of Peptide & Protein Chemistry & Biology

After completion of an International PhD degree in 1990, under the supervision of Professor Luis Moroder at the Max Planck Institute for Biochemistry, she launched in 1991 a comprehensive peptide-based translational research program and founded the first laboratory of peptide chemistry at the University of Florence. She was Associate Professor of Bioorganic Chemistry (2001-2019) and in 2020, she was appointed Full Professor at the University of Florence. She is Laureate of the “Chaire d’Excellence” 2009-2014 of the French “Agence Nationale de la Recherche” (unique for chemistry out of 16) for the project “PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases”. The project was developed at the Université Paris-Seine (now CY Cergy Paris Université), where she was appointed Full Professor of Bioorganic chemistry, founding and being Director of the platform PeptLab@UCP, born to support start-up companies involved in R&D of peptide-based products (2008-2020). In 2009, she started the French-Italian Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology (PeptLab) that she coordinates, associating the Departments of Chemistry and NeuroFarBa (Section of Pharmaceutical Sciences) of the University of Florence and PeptLab@UCP in France. In June 2019, at PeptLab@UCP, she launched a facility for large-scale production of peptides with the Liberty Pro MW-assisted synthesizer, the technology she trusted for its unique performances since she purchased, in 2005, the first MW-peptide synthesizer installed in Europe, at PeptLab at the University of Florence. In recognition of her outstanding contribution to peptide science, in 2008, she was the recipient of the Leonidas Zervas Award of the European Peptide Society and of the First Dimitrios Theodoropoulos Memorial Award of the Hellenic Peptide Society. She was awarded the Rita Levi Montalcini Prize 2019-2021 for the binational cooperation between Italy and Israel to develop her program aimed to characterise possible unknown bacterial and/or viral infections triggering immune-mediated diseases using aberrantly glycosylated peptide antigens and recognized with the Barry Cohen Prize 2024 for Medicinal Chemistry/Chemical Biology that was attributed by the Israel Chemical Society on July 18, 2024 at the Weizmann Institute of Science, Rehovot, after presenting a keynote lecture. Since 2013, she is delegate of the International Affairs and Erasmus Program of the School of Mathematical, Physical, and Natural Sciences of the University of Florence supporting and orienting students interested in international education pathways and since 2021 she is Director of the Phd Programme in Chemical Sciences of the University of Florence, confirmed for a second term till 2027. She contributed to launch several double degrees in Chemical sciences for 2-year Masters (Hebrew University of Jerusalem, University of Burgos, Rouen Normandie, Paris Sciences et Lettres) and for PhDs (Wroclaw University of Science and Technology, University of Cergy-Pontoise, University of Rouen Normandie, Ecole Normale Supérieure-University Pierre et Marie Curie). She has been Treasurer and Member of the Executive Committee of the European Peptide Society (2011-2020) and still is Councillor of the American Peptide Society (2019-2025). In 2015, she was founding member of the Italian Peptide Society and she was appointed scientific officer of the executive committee since 2017. She organised several meetings, among them, she was chair with Phil E. Dawson of the 2016 Gordon Research Conference “Crossing Barriers by Peptide Science for Health and Wellness” and on August 25-31, 2024 she cochaired with Paolo Rovero the 14^th International Peptide Symposium/37^th European Peptide Symposium (www.eps2024.com) that took place at Palazzo dei Congressi in Florence (Italy) with 1049 participants from 45 countries and all the 5 continents. Three parallel workshops were organised at Plesso Didattico Morgagni of the University of Florence on Friday, August 30 and Saturday, August 31, right after the main symposium, on hot topics, i.e., 1) Applications of computational AI/ML in peptide research with a roadmap to peptide drug and material development; 2) Embracing innovation and sustainability in peptide synthesis; 3) Navigating entrepreneurship and technology transfer in peptide discovery and development (supported in part by EUniWell, Project TTpep: Technology Transfer of Peptides for the Well-being Economy). In 2003 she cofounded the first spin-off of the University of Florence, EspiKem Srl, that managed the valorisation of a peptide-based anti-aging cosmeceutical product, Definisse KP1, developed in her academic laboratories and launched on the global market on September 2023 by Relife, the aesthetic medicine division of Menarini group. Moreover, she cofounded and acted as CSO of the start-up Toscana Biomarkers Srl (2007-2014), with the R&D mission to innovate and licensing intellectual property of peptides for diagnostic kits of autoimmune diseases. Distinguished for activity in technology transfer, she received the 2009 Frost & Sullivan Excellence in Research Award in the European autoimmune disease diagnostics market and the Vespucci Award of the Region Toscana for the development of a company aimed to research and produce innovative peptide-based diagnostic methodologies for autoimmune diseases. In 2016, she founded and is Director of the Toscana EU-Region technology transfer Laboratory of Molecular Diagnostics and Life Sciences (MoD&LS) where she coordinated the standardisation of the HPLC-MS analyses of ca. 60 endocrine disrupting chemicals and their metabolites in more than 4000 biological fluids of children and their mothers (urines, sera and breast milk) to associate their presence with children disease development such as autism, obesity, and insulin resistance. Moreover, she has been scientific supervisor of the PeptLab and Fabbrica Italiana Sintetici Spa joint laboratory PeptFarm, for GMP large-scale peptide synthesis in Vicenza. Recently thanks to a cooperation with Protein Technologies AB (Sweden) she has been involved in a joint industrial PhD to develop sustainable strategies for peptide production with a holistic approach integrating green solvents and reagents, automatic peptide synthesizers and low impact purification platforms. She worked as panel member, evaluator and rapporteur for several funding European agencies (2012-2019 - Panel Member for ERC Advanced Grant evaluation PE5 – Synthetic chemistry and materials, REA HE-MSCA-PF-2018-2024; ESF-FWO 2018-2024), and national Agencies in Europe (Research Council of Lithuania 2018-2023; Polish National Science Centre 2018-2023, etc.) and in the world (CANADIAN INSTITUTES OF HEALTH RESEARCH, Israeli German Foundation, etc.) to select projects. She is coauthor (ORCID: 0000-0002-2947-7107) of 399 peer-reviewed publications indexed by WOS (ID: JAX-3042-2023, 05/02/2025), 212 indexed by Scopus (ID: 7005551589) and of 11 filed patents some of them licensed to companies, including the coupling reagents TBCRs . She presented worldwide 161 invited lectures in International Symposia, Universities, and Research Centres (31 aimed to technology transfer). Her laboratory has communicated 76 oral and 295 poster presentations at international symposia. In her independent career, she has trained 40 PhDs and 82 undergraduate students (55 M.Sc. and 27 B.Sc.), 16 post-doctoral fellows and 11 research assistants, with focus on the characterisation of aberrant post-translational modifications and biomarkers of immune-mediated diseases, structure-activity relationship studies, and efficient synthetic strategies for metabolic stabilization by strategic side-chain to side-chain cyclization. Her PhD students have received important distinctions, including the 2024 XX Edition of Antonio Bardazzi Award 2023, “Sara Lapi” Award for the Best Master Theses in Chemistry, the 2016 Louis Forest “Prix de la Chancellerie des Universités de Paris”, the 2005 Bert Schram Young Investigator Honorable Mention, and the 1999 Bruce W. Erickson Award from the American Peptide Society.

Anna Maria Papini is married and has two daughters (Giulia 09/05/1991 and Elena 10/04/1996)

Firenze (Italy), June 11, 2025

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Full Professor of Bioorganic Chemistry and director of the Interdepartmental Research Unit of Peptide & Protein Chemistry & Biology. After completing an International PhD in 1990 (supervisor Prof. L. Moroder, Max Planck Institute for Biochemistry), in 1991 she founded the first Laboratory of peptide chemistry, starting peptide-based translational research at the University of Florence.

After completion of an International PhD degree in 1990, under the supervision of Professor Luis Moroder at the Max Planck Institute for Biochemistry, she launched in 1991 a comprehensive peptide-based translational research program and founded the first laboratory of peptide chemistry at the University of Florence. She was Associate Professor of Bioorganic Chemistry (2001-2019) and in 2020, she was appointed Full Professor at the University of Florence. She is Laureate of the “Chaire d’Excellence” 2009-2014 of the French “Agence Nationale de la Recherche” (unique for chemistry out of 16) for the project “PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases”. The project was developed at the Université Paris-Seine (now CY Cergy Paris Université), where she was appointed Full Professor of Bioorganic chemistry, founding and being Director of the platform PeptLab@UCP, born to support start-up companies involved in R&D of peptide-based products (2008-2020). In 2009, she started the French-Italian Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology (PeptLab) that she coordinates, associating the Departments of Chemistry and NeuroFarBa (Section of Pharmaceutical Sciences) of the University of Florence and PeptLab@UCP in France. In June 2019, at PeptLab@UCP, she launched a facility for large-scale production of peptides with the Liberty Pro MW-assisted synthesizer, the technology she trusted for its unique performances since she purchased, in 2005, the first MW-peptide synthesizer installed in Europe, at PeptLab at the University of Florence. In recognition of her outstanding contribution to peptide science, in 2008, she was the recipient of the Leonidas Zervas Award of the European Peptide Society and of the First Dimitrios Theodoropoulos Memorial Award of the Hellenic Peptide Society. She was awarded the Rita Levi Montalcini Prize 2019-2021 for the binational cooperation between Italy and Israel to develop her program aimed to characterise possible unknown bacterial and/or viral infections triggering immune-mediated diseases using aberrantly glycosylated peptide antigens and recently recognized with the Barry Cohen Prize 2024 for Medicinal Chemistry/Chemical Biology that was attributed by the Israel Chemical Society on July 18, 2024 at the Weizmann Institute of Science, Rehovot, after presenting a keynote lecture. Since 2013, she is delegate of the International Affairs and Erasmus Program of the School of Mathematical, Physical, and Natural Sciences of the University of Florence supporting and orienting students interested in international education pathways and since 2021 she is Director of the Phd Programme in Chemical Sciences of the University of Florence, recently confirmed for a second term. She contributed to launch several double degrees in Chemical sciences (Hebrew University of Jerusalem, University of Burgos, Rouen Normandie, Paris Sciences et Lettres). She has been Treasurer and Member of the Executive Committee of the European Peptide Society (2011-2020) and still is Councillor of the American Peptide Society (2019-2025). In 2015, she was founding member of the Italian Peptide Society and she was appointed scientific officer of the executive committee since 2017. She was chair with Phil E. Dawson of the 2016 Gordon Research Conference “Crossing Barriers by Peptide Science for Health and Wellness” and on August 25-31, 2024 she will cochair the 14^th International Peptide Symposium/37^th European Peptide Symposium (www.eps2024.com) that will take place in Florence (Italy). In 2003 she cofounded the first spin-off of the University of Florence, EspiKem Srl, that managed the valorisation of a peptide-based anti-aging cosmeceutical product, Definisse KP1, developed in her academic laboratories and launched on the global market on September 2023 by Relife, the aesthetic medicine division of Menarini group. Moreover, she cofounded and acted as CSO of the start-up Toscana Biomarkers Srl (2007-2014), with the R&D mission to innovate and license peptide-based intellectual property for diagnosis of autoimmune diseases. Distinguished for activity in technology transfer, she received the 2009 Frost & Sullivan Excellence in Research Award in the European autoimmune disease diagnostics market and the Vespucci Award of the Region Toscana for the development of a company aimed to research and produce innovative peptide-based diagnostic methodologies for autoimmune diseases. In 2016, she founded and is Director of the Toscana EU-Region technology transfer Laboratory of Molecular Diagnostics and Life Sciences (MoD&LS) where she coordinated the standardisation of the HPLC-MS analyses of ca. 60 endocrine disrupting chemicals and their metabolites in more than 4000 biological fluids of children and their mothers (urines, sera and breast milk) to associate their presence with children disease development such as autism, obesity, and insulin resistance. Moreover, she has been scientific supervisor of the PeptLab and Fabbrica Italiana Sintetici Spa joint laboratory PeptFarm, for GMP large-scale peptide synthesis in Vicenza. Recently thanks to a cooperation with Protein Technologies AB (Sweden) she has been involved in a joint PhD to develop sustainable strategies for peptide production with a holistic approach integrating green solvents and reagents, automatic peptide synthesizers and low impact purification platforms. She is coauthor of 370 peer-reviewed articles (WOS 30/06/2024) and of 11 filed patents. She presented worldwide 140 invited lectures in International Symposia, Universities, and Research Centres (28 aimed to technology transfer). Her laboratory has communicated 59 oral and 251 poster presentations at international symposia. In her independent career, she has trained 38 PhDs and 82 undergraduate students (55 M.Sc. and 27 B.Sc.), 16 post-doctoral fellows and 11 research assistants, with focus on the characterisation of aberrant post-translational modifications and biomarkers of immune-mediated diseases, structure-activity relationship studies, and efficient synthetic strategies for metabolic stabilization by strategic side-chain to side-chain cyclization. Her PhD students have received important distinctions, including the 2023 “Sara Lapi” Award for the Best Master Thesis in Chemistry, the 2016 Louis Forest “Prix de la Chancellerie des Universités de Paris”, the 2005 Bert Schram Young Investigator Honorable Mention, and the 1999 Bruce W. Erickson Award from the American Peptide Society.

Firenze (Italy), June 20, 2024

Anna Maria Papini, PhD: Curriculum Vitae et studiorum 

Full Professor of Organic Chemistry, Department of Chemistry “Ugo Schiff”, University of Florence, Coordinator of the Interdepartmental Research Unit of Peptide & Protein Chemistry & Biology (PeptLab), Director of the Centre of Competences in Molecular Diagnostics & Life Sciences (MoD&LS).

Education and Scientific Graduation

1977-1983: Italian “Laurea” in Chemistry, Curriculum Organic Chemistry & Chemical Biology of the University of Florence (Italy). Title of the “Laurea” thesis: Regioselective functionalisation of cyclic ethers and thioethers: synthesis of bifunctional derivatives via IVB organometallic compounds”.

1985-1989: International Ph.D. in Chemical Biology of the Italian Ministry of Education Title of the PhD thesis (fellowship of the Italian Ministry of Education) performed in 1985-1986 at the Department of Biochemistry, University of Sherbrooke, Québec, Mentor Prof. Dr. Gilles Dupuis; in 1986-1988 at the Dept. of Organic Chemistry, University of Florence, Mentor: Prof. Gianfranco. Rapi and in 1988-1989 at the Department of Peptide Chemistry, Max Planck Institute für Biochemie, Martinsried Bei Muenchen, Mentor Prof. Dr. Luis Moroder. Title of the PhD thesis: “Synthesis of peptides for chemical, bio-pharmacological and immunological studies”. Tutors: Prof. Gianfranco Rapi and Prof. Luis Moroder.

1990: Specialisation in Dermatochemistry, Dermatological Department of the Florence University Hospital. Supervisor Pr. M.D. E. Panconesi.

Since 2013: Habilitation to the function of Full Professor of Organic Chemistry of the Italian Universities.

Since 2001: Habilitation to the function of Full Professor of Organic Chemistry of the French Universities.

Professional appointments

Since March 1, 2020 to date: Appointed Full Professor ("Professore I fascia") of Organic Chemistry at the Department of Chemistry “Ugo Schiff” of the University of Florence (Italy).

November 2002-February 2020: Associate Professor ("Professore II fascia") of Organic Chemistry and Chair of Bioorganic Chemistry at the Department of Organic Chemistry and since 2011 Department of Chemistry “Ugo Schiff” of the University of Florence.

2001-2002: Researcher ("Ricercatore universitario a tempo indeterminato") of Organic Chemistry at the Department of Organic Chemistry, University of Florence.

1991-2001: Assistant Researcher ("Tecnico Laureato") at the Department of Organic Chemistry of the University of Florence, associated to the Chair of Chemistry for the Medical School.

2008-2020: Appointed Full Professor with the “Chaire d’Excellence” of the French “Agence Nationale de la Recherche” (ANR-09-CEXC-013-01), Section 32 (Chimie Organique Minérale et Industrielle) of the Université Paris-Seine, now CY Cergy Paris University (France). Detached to the University of Florence on September 2020 (Article 14-6 of the Law of French Universities).

2001: Awarded Full Professor of Organic Chemistry at the Claude Bernard University Lyon 1 (France). Waiver.

Coordination of Research groups

Since 2004 to date: Co-founder and head of the Interdepartmental Research Unit of Peptide & Protein Chemistry & Biology at the Polo Scientifico of the University of Florence, associating the Departments of Chemistry and NeuroFarBa (Section of Pharmaceutical Sciences) of the University of Florence (Italy) (PeptLab@UNIFI).

Since 2016 to date: Founder and Director of the Laboratory Molecular Diagnostics & Life funded by EU-Region Toscana to support R&D in diagnostics in SMEs.

Since 2017 to date: Associated to the CNR Institute of Crystallography (www.ic.cnr.it/ic4/en/).

2017-2020: Scientific supervisor of the Joint Laboratory PEPTFARM (joining PeptLab and FIS – Fabbrica Italiana Sintetici Spa, Vicenza working in MoD&LS) for technology transfer of large-scale MW-assisted peptide synthesis of Eptifibatide Active Pharmaceutical Ingredient, aimed to validation of a GMP plant in Vicenza (see doi.org/10.1021/acs.oprd.0c00490).

2013-2020: Founder and Director of the Platform PeptLab@UCP of the Université Paris-Seine, Cergy-Pontoise, since 2020 CY Cergy Paris Université (France).

2009-2020: Founder and coordinator of the French-Italian Interdepartmental Research Unit of Peptide & Protein Chemistry & Biology associating PeptLab@UNIFI and the Platform PeptLab@UCP at the Université Paris-Seine, Cergy-Pontoise, now CY Cergy Paris Université (France) (www.peptlab.eu).

Academic Roles and Responsabilities

Since 2021 to date: Elected Coordinator of the PhD Course in Chemical Sciences of the University of Florence (since XXXVII Edition).

Since 2010 to date: Member of the Board of the PhD Course in Chemical Sciences of the University of Florence.

Since 2013 to date: Delegate of the International Affairs of the School of Mathematical, Physical, and Natural Sciences (SMFN) of the University of Florence (Italy) and Responsible of the Erasmus + Exchanges Programs for Study and Traineeship of the students incoming and outcoming (ca. 300 students/year) of the School of SMFN (Physics, Chemistry, Mathematics, Informatics, Biological and Natural Sciences, Earth sciences, Optics, Biotechnology, Cultural Heritage). Responsible of the Erasmus + Exchanges Programs for Staff Teaching and Administrative Mobility worldwide.

Since 2005 to date: Coordinator of the Erasmus Program of Chemistry of the Faculty of SMFN of the University of Florence (Italy). Responsible of Erasmus Exchange Programs for Study and Traineeship of the students of Chemistry Degrees (B.Sc., M.Sc., PhD).

Since October 2020 to date: In charge of the activities implemented in the context of the "European Universities for well-Being" (EUniWell) funded by the EC-EACEA, Erasmus+ Program - European Universities (Responsible of the WG Guidelines for Course Design and Co-responsible of the WG on Entrepreunership).

Since December 2020: Elected member of the Board of the School of SMFN to represent the Department of Chemistry “Ugo Schiff” of the University of Florence.

Since 2018 to date: Member of the Teaching Committee for the BSc and MSc Courses in Chemistry of the University of Florence

Since 2016 to date: Responsible of the foreign internship for the BSc and MSc Courses in Chemistry of the University of Florence

Since 2019 to date: Coordinator of the foreign internship for the MSc students in Advanced Molecular Sciences of the University of Florence.

2006-2009: Member of the Board of the PhD School in Non-linear systems and complex dynamics of the University of Florence.

2010-2014: Delegate of the Faculty of SMFN in the Board of the Foreign Language Centre (CLA - "Centro Linguistico d’Ateneo") of the University of Florence.

2006-2016: Vice President and Delegate for Chemistry in the Board of OpenLab (Educational program of the Faculty of Sciences of the University of Florence).

2012: Member of the Committee for the selection of TFA A059 (Educational Trainings for teachers of chemistry in high schools).

2011: Representative of the Department of Chemistry of the University of Florence in the Pole of innovation for life sciences (“Polo d’Innovazione per le Scienze della Vita”).

Awards for the scientific activity

2019-2021: Rita Levi Montalcini Prize 2019 (postponed to 2020 for COVID-19) for the binational Italian-Israeli Cooperation for the project “Role of glycopeptides in immune-mediated diseases”. 4-Month scientific visits in Israel: Azrieli Faculty of Medicine, Bar Ilan University, Safed (Prof. Nir Quit); Department of Immunology, Weizmann Institute of Sciences, Rehovot (Dr. Rina Aharoni and Prof. Ruth Arnon); Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem (Dr. Mattan Hurevich, Prof. Assaf Friedler, and Prof. Shlomo Yitzchaik).

2009-2013: "Chaire d’excellence" of the French "Agence Nationale de la Recherche (unique of chemistry out of 16 attributed in 2009), ANR-09-CEXC-013-01, Project “PepKit : Development of peptide-based-diagnostic kits for autoimmune diseases”.

2008: Leonidas Zervas Award for outstanding contribution to peptide chemistry, 30th EPS, Helsinki (Finland), August 31, 2008.

2008: 1st D. Theodoropoulos Memorial Lecture Award for outstanding achievements in Peptide Sciences, 6th Hellenic Forum on Bioactive Peptides, Patras (Greece), May 18, 2008.

2006: Best Poster Award Lucio Senatore, XXII Congresso Nazionale della Società Chimica Italiana [V. Volkov, F. Nuti, Y.Takaoka, R. Chelli, A.M. Papini, and R. Righini. Structure and bonding of water molecules in the polar region of phospholipid membrane investigated by two-dimensional IR spectroscopy and MD computer simulation. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, September 10-15, 2006, Abstract FIS-P-135] attributed to the work performed with the Postdoc student F. Nuti and of the coworker R. Chelli.

2005: Bert Schram Price. Honorable Mention, 19th American Peptide Symposium, San Diego, California, USA [B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, and A.M. Papini. Cross-reactivity studies of rMOGED with the synthetic putative autoantigen CSF114(Glc) and [N31(Glc)]hMOG(30-50) in Multiple Sclerosis patient sera. 19th American Peptide Symposium (San Diego, CA, USA), June 18-24, 2005, LY 03, Abstract p. 484] attributed to the work performed with the PhD student B. Mulinacci.

2005: Best Poster Award Glycoconjugates “Glyco XVIII”, Florence, Italy [F. Nuti, I. Paolini, B.Mulinacci, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, and A.M. Papini. Sugar-scan of CSF114(Glc) for autoantibody recognition in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates. Glyco XVIII”, Firenze, September 4-9, 2005, Abstract P057, Glycoconjugate J., 2005, 22(4–6), 254] attributed to the work performed with the PhD student F. Nuti.

1999: Bruce W. Erickson Award for outstanding achievement in peptide sciences, 16th American Peptide Symposium, Minneapolis, Minnesota, USA [E. Nardi, S. Mazzucco, S. Matà, M. Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli and A.M. Papini. Influence of different N-linked glycosyl moiety at position 31 of hMOG(30-50) on anti-MOG antibody recognition in multiple sclerosis patients. 16th American Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P148] attributed to the work performed with the PhD student E. Nardi.

Technology transfer activity

2017-2020: Founder and Scientific Coordinator of PEPTFARM, joint laboratory between PeptLab of the University of Florence and Fabbrica Italiana Sintetici, F.I.S. S.p.a. (Vicenza, Italy) to transfer the technology for GMP large-scale synthesis of active pharmaceutical peptide drugs (research activity performed in MoD&LS).

Since July 2020 to date: Technology transfer of a peptide-based cosmeceutical IP of AM Papini’s Team to an international company (to be discosed January 2022).

2013-2020: Founder and Director of the PeptLab@UCP Platform at the University of Cergy-Pontoise that in 2019 launched the large-scale facility for MW-assisted peptide synthesis at CY Cergy Paris Université, aimed to technology transfer to SMEs.

Since 2016 to date: Founder and Director of the Toscana EU-Region technology transfer Laboratory of Molecular Diagnostics and Life Sciences (MoD&LS) aimed to R&D of peptide-based diagnostics.

Since 2016 to date: Founder and member of the Board of the start-up company Apotech S.r.l. for R&D of peptide-based cosmeceuticals that developed KP1 as anti-aging cream based on the peptide analog of Serpin A1, inhibitor of collagen degradation (doi:10.1002/cmdc.201500472). The cream is commercialized by Apotech S.r.l.

Since 2014 to date: Member of the Scientific Advisory Board of Regulaxis (www.regulaxis.com).

2007-2016: Founder & Chief Scientific Officer of the startup Toscana Biomarkers S.r.l. whose mission was R&D of peptide-based diagnostics of autoimmune diseases. Toscana Biomarkers IP was licensed to European IVD producers: Diametra (Milano, Italy), Theradiag (Paris, France), etc.

Since 2003 to date: Founder and member of the Board of EspiKem, 1st spinoff of the University of Florence, presently acting as CRO selling custom peptides for research (cooperating with PeptLab).

Awards for the technology transfer activity

2009: Vespucci Award for founding the startup Toscana Biomarkers S.r.l.

2008: Frost & Sullivan Excellence in Research Award in the European autoimmune disease diagnostics market presented to A.M. Papini for the start-up Toscana Biomarkers S.r.l.

2006: Start-Cup for the business plan of the start-up Toscana Biomarkers S.r.l.

2004: Vespucci Award, Research & Ethical Innovation to A.M. Papini as inventor of the patent PCT (2003) WO 03000733 A2.

Recent Research Funding as Principal Investigator

2020-2024: “Mother and Infant dyads: Lowering the impact of endocrine disrupting Chemicals in milk for a Healthy Life” LIFE18 ENV/IT/000460 “life MILCH”. Total cost of the project for the University of Florence € 711.028 (UNIFI will contribute with € 326.150 of own financial resources and will receive from the coordinating beneficiary a maximum amount of € 384.878).

2021-2022: “Regione Toscana POR FESR 2014-2020” R&D of SMEs project: ECO-SMART DEGREASING SYSTEM 4.0. Total cost of the project € 1.497.849,55 (UNIFI € 204.700,00).

2017-2019: “Regione Toscana POR CReO FESR 2014-2020” project: EcoReLabel: Ecological removable and recyclable labels. € 303.000,00.

2010-2012: “Regione Toscana POR CReO FESR 2007-2013” project: MARK - Identification of diagnostic biomarkers of autoimmune diseases. € 450.000,00.

2005-2011: “Fondazione Cassa di Risparmio di Firenze”. Molecular characterisation of peptide-protein interaction in autoimmune diseases. 1.500.000 Euro for PeptLab at the University of Florence.

2005-2007: International FIRB - Italian Ministry of University & Research and Harvard Medical School. € 350.000,00.

2002-2003, 2005-2006, 2008-2009: PRIN-Italian Ministry of University & Research. Design, synthesis & immunological characterisation of modified peptides to follow up autoimmune diseases. € 700.000,00.

2009-2014: “Chaire d’Excellence” (ANR-09-CEXC-013-01). PepKit: Development of peptide-based-diagnostic kits for autoimmune diseases.€ 999.998,00 for the PeptLab@UCP platform at Université Paris-Seine, Cergy-Pontoise (France).

2018: Région Ile de France, funding dedicated to launch the large-scale facility KgPeptLab@UCP at Université Paris-Seine, Neuville site, Cergy Pontoise (France), including the Large-scale MW-assisted peptide synthesizer (CEM, Charlotteville, NC, USA). € 800.000,00.

2016-2018: Lauréate MRSEI-ANR Edition 2015, EU Project REDIPOC to organize and submit a FET-OPEN project for a Reliable Diagnostic Point Of Care Network. € 20.000.

2013-2016: PhD grant by ANRT Thèse CIFRE in cooperation with REGULAXIS. € 90.000.

2015-2018: BIRAC, Indo-French Challenge-oriented Call for proposals 2014. “AMIR-PepKit IVD, R&D of a peptide-based-diagnostic kit for an early detection of a fatal immune response in acute myocardial infarction patients”. € 50.000,00.

2011-2013: Fondation Pierre-Gilles de Gennes. “Immune-mediated diseases: Glycopeptidomic-based diagnostics to follow-up disease activity”. 2 post-doctoral fellows + € 90.000,00 for materials.

Panel Member of international evaluation committees

EUROPE

2012-2019: Panel Member for ERC Advanced Grant evaluation, PE5 – Synthetic chemistry and materials, Brussels (attended 4 panels, 2 meetings in Brussels every two years).

2020: Individual Fellowships Evaluator and Rapporteur (EX2006A195962) for the Marie Curie Sklodowska-Curie Actions, H2020-MSCA-IF-2020, European Research Executive Agency (remote evaluation 2/10/2020-4/12/2020).

2019: Individual Fellowships Evaluator for the Marie Curie Sklodowska-Curie Actions, H2020-MSCA-IF-2019, European Research Executive Agency (remote evaluation, 7/10/2019-6/12/2019).

2018: Individual Fellowships Evaluator for the Marie Curie Sklodowska-Curie Actions, H2020-MSCA-IF-2018, European Research Executive Agency (remote evaluation, 25/09/2018-15/11/2018).

2019: Member of the panel to evaluate the Erasmus Mundus joint Master Degree SERP+ (for Qualifications in the European Higher Education Area - FQ-EHEA), a two-year programme in Surface, Electro, Radiation, and Photo-Chemistry with elements of Management, Business, Innovation and Valorisation, Communication and Patent law (Université Paris-Sud, Universidade de Porto, Università degli studi di Genova, Uniwersytet im. Adama Mickiewicza). Poznan (Poland), June 1-3, 2019.

2018: Member of the training committee for the implementation of the European Approach to Quality Assurance of Erasmus Mundus Joint Master Degrees. 12-14 November 2018, COLOGNE (Germany).

FRANCE

Since 2021 to date: Member of the Scientific Commitee of ChimieParistech, Paris, France

2020: Panel member (representing the CNU Section 32) of the French High Council for Evaluation of Research and Higher Education (HCERES) for the evaluation committee Group A of the Unit “Institut de Biomolécules Max Mousseron”, Montpellier, France (February 25-28, 2020).

2019: Nominated member of the Scientific Evaluation Committee N° 44 " Biochemistry of living organisms " for the French “Agence Nationale de la Recherche”. ChâteauForm, République, 8 Bis Rue De La Fontaine Au Roi, 75011 Paris (France), January 14-15, 2019 and June 17-18, 2019.

2017: Vice-president of the French High Council for Evaluation of Research and Higher Education (HCERES) evaluation committee Group D of the Unit Molecules of Communication and Adaptation of Microorganisms (MCAM) UMR 7245 CNRS Muséum National d’Histoire Naturelle (MNHN), 6-7 December 2017, Paris.

2016-2019: Elected member of the “Conseil Nationale des Universités” - CNU (France) to deliberate habilitations and promotions of the French University researchers and professors (4 meetings of 1 week/year for "Qualifications PR et MCF, PEDR, Progression de carrière, CRCT).

2011: Member of the AERES Committee for evaluation of the ICM of the University of Reims, February 26-28, 2011.

2011 & 2012: Member of the Evaluation Committee of research projects submitted to the “Fondation de la Recherche Médicale”, Paris, France.

2010: Member of the AERES Committee for the evaluation of iBiTecc-S Equipe SIMOPRO (CEA, Saclay), March 28-30, 2010.

LITHUANIA

2021: Leader of the expert Panel commission for the Research Council of Lithuania for the Call for proposals Promotion of Postdoctoral Fellows. Evaluation of 26 projects of Natural, Technical, and Medical Sciences (March 8, 2021-May 13, 2021. 2 Steps, 2nd step on April 20, 2021 held remotely using Microsoft TEAMS platform).

2021: Leader of the expert Panel commission for the Research Council of Lithuania for the Call for proposals for Lithuanian-Polish programme. Evaluation of 30 projects in the field of Natural, Technical, Agricultural, and Medical Sciences (February 3, 2021-March 24, 2021. 2 Steps, 2nd step on February 25, 2021 held remotely using Microsoft TEAMS platform).

2020: Member of the expert commission of the Research Council of Lithuania for the X Call for proposals for the Implementation of researcher groups projects for 2021-2024. Evaluation of 34 projects in the field of Natural, Technical, Agricultural, and Medical Sciences (November 17, 2020-January 30, 2021. 2 Steps, 2nd step on December 17, 2020 held remotely using Microsoft TEAMS platform).

2020: Leader of the expert panel commission for the Research Council of Lithuania for EEA Financial Mechanism 2014-2021, Baltic Research Programme, Call for Proposals in Lithuania, evaluation of 11 projects in the field of Natural, Technical, and Medical Sciences (July 1-9, 2020).

2020: Leader of the expert panel for the Research Council of Lithuania for the Evaluation of "Implementing World-class R&D Projects (SMART)" of 22 projects in the field of Natural, Technical, Medical and Agricultural Sciences (May 7-8, 2020).

2020: Member of the expert panel and acting as Leader of the expert panel for the Research Council of Lithuania for the “Distinguished Professor Programme”. Evaluation of 12 projects in the field of Natural, Technical, Medical and Agricultural Sciences (February 1-March 5, 2020).

2019: Member of the expert commission of the Research Council of Lithuania for the Competitive Funding of Research and Dissemination Projects (evaluation of 27 projects). Two-stage evaluation process: 1st stage individual expert assessment of the proposal remotely (by March 17, 2019); 2^nd stage participation at the panel assessment followed by the summary evaluation on March 22, 2019, 9:00-18:00, Research Council of Lithuania in Vilnius (Gedimino av.3, Room 212), Lithuania.

2018: Panel member as expert of bioorganic chemistry and chemical biology for assessment of research and development of the universities and research institutions of Lithuania in the field of physical sciences, 24-29 September 2018, Vilnius.

SPAIN

2019-2021: Nominated as 1 out of 8 members of the External Scientific Advisory Board of The Institute for Advanced Chemistry of Catalonia (IQAC), belonging to the Spanish National Research Council (CSIC), and devoted to research of excellence in Chemical Sciences, as a leading scientist in peptide chemistry and the application of peptides in different fields (1st Meeting in Barcelona, Catalonia 25-26 November 2019).

POLAND

2018: Panel member of the Foundation for Polish Science to select the winners of the First Team programme, edition 5/2018, 26-27 July 2018, Warsaw (Poland).

SLOVENIA

2016: Evaluation panel member for Promotion of Research and Development Programs Implementation for the Ministry of Education, Science, and Sport, Republic of Slovenia, Ljubljana, June 3-4, 2016.

Remote Referee of international evaluation committees

2019-2020: Expert member for the European Science Foundation

2017: Expert member for the German-Israeli Foundation (GIF) for Scientific Research and Development to evaluate projects presented at the GIF Regular Program.

2016: External Member of an “Ad Hoc Committee” for promotion review at The Scripps Research Institute (TSRI) of candidates to the rank of Associate Professor with Tenure.

2016: Appointed evaluator for research projects submitted to the United States – Israel Binational Science Foundation (BSF).

2016: Appointed External evaluator of candidates for Faculty Positions in the subject field “Organic Chemistry with emphasis on Chemistry” at the University of Patras (Greece).

2015-2016: Appointed Reviewer for research projects submitted to the executive government agency of the Polish National Science Centre (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl).

2014: Appointed reviewer for “Vienna Science and Technology Fund (VSTF, Austria)” to evaluate proposals submitted to the Vienna Research Groups for Young Investigators call in the field of “Life Sciences”.

2014: Appointed reviewer for the National Science Centre in Poland (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl) to evaluate projects in the Funding scheme PRELUDIUM.

2011-2013: Appointed reviewer for the “Association Nationale Recherche et Technologie (ANRT, Paris, France) to evaluate proposals “CIFRE” (Conventions Industrielles de Formation par la Recherche) to fund PhD fellowships to be perfomed 50% in industrial environments.

2012-2017: Referee for the Evaluation of the quality of the research of the Italian Universities (VqR )

2010-2020: Member of the Council of “Ordine dei Chimici della Toscana” (Society of Chemists in Tuscany).

Organisation of International Symposia

2024: Elected in 2016 by the General Assembly of the European Peptide Society Chairperson of the 14th International Peptide Symposium/37th European Peptide Symposium that will be held in Florence (Italy), 25-30 August 2024 (after two postponed dates scheduled for COVID-19).

2019: Chairperson of the “Giornata scientifica della Società Italiana Peptidi dedicata ai Soci Giovani, Premio scientifico Vittorio Erspamer. September 21, 2019, Polo Didattico Morgagni, University of Florence, Viale Morgagni 44, Firenze (Italy).

2019: Chairperson with Fernando Albericio of the International Oligonucleotides and Peptides Conference, Track Peptides, Ramada Plaza Hotel, Milano (Italy), September 17-18, 2019.

2019: Chairperson Session III: Peptide Nutraceutics and Cosmeceutics and Session IV: Peptide Engineering and Smart Materials, CIS 2019 - Chemistry meets Industry and Society, Società Chimica Italiana, WS3 – Smart Peptide Chemistry for next generation industry in a sustainable society, Grand Hotel Salerno, Salerno (Italy), August 28-30, 2019.

2016: Chairperson of the 2016 Gordon Research Conference: Chemistry & Biology of Peptides: Crossing Barriers by Peptide Science for Health and Wellness, with Prof. Dr. P. Dawson, Ventura, CA (USA), 21-26/02/2016

2014: Vice-chair of the Gordon Research Conference: Chemistry & Biology of Peptides: Peptide Science in the Era of Synthetic Biology, Ventura, CA (USA), 23-28/02/2014.

2016: Chairperson of 1st Mass Spectrometry Peptide Day, Convento di Sant’Apollonia, Firenze, 10-12 February 2016 (http://www.spettrometriadimassa.it/Congressi/1MS-PeptideDay/)

2014: Chairperson of the International Symposium Peptides in Paris PIPS 2014 and Training Course 5-10 October 2014. Co-editor of the special issue in Biopolymers Peptide Science together with S. Lavielle (UPMC, Paris) and W.D. Lubell (Université de Montreal).

2014: Responsible of the thematic semester “Peptides & Proteins Molecules of Life. Université de Cergy Pontoise (France) as final event of the Chaire d’Excellence 2009-2014.

2011: Chair of the Symposium "PEPTIDES AND PROTEINS IN THE NEW MILLENNIUM" organised in honour of the Doctorate Honoris Causa attributed from the Université de Cergy-Pontoise to Prof. Luis Moroder in Neuville-sur-Oise (France), 5-6 October, 2011.

2011: Chair of the Symposium MAOPS2 - Microwave-Assisted Organic Peptide Synthesis, Chiostro del Maglio, Firenze (Italy), 26-28 April 2011.

2010: 1st Italy-Australia Peptide Symposium on Biomolecules for Diagnostics & Therapeutics, Satellite of 31st European Peptide Symposium, Monash University, Prato (Italy), 10-12 September, 2010.

2007: EUROCOMBI4, 1st International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalyst and Materials, Chiostro del Maglio, Firenze (Italy), 15-18 July, 2007.

2006: International Training Course on Mass Spectrometry & High Performance Liquid Chromatography of Proteins (sponsored by UNESCO), Polo Scientifico, Università di Firenze, 1-12 May 2006.

2003: 1st Practical Training Course: Innovative Combinatorial Approches and Technologies (sponsored by European Society of Combinatorial Sciences,) Polo Scientifico, Università di Firenze, 9-11 April, 2003.

Member of scientific committees of international symposia

Since 2020 to date: Member of the Scientific Advisory Board of the 12th International Peptide Symposium/36^th European Peptide Symposium, Sitges (Spain) August 28-September 2, 2022.

2020: Member of the Scientific Committee of the 3rd Meeting of the Italian Peptide Society, December 12, 2020 (Webinar, Rome, Italy).

2018: Member of the Scientific Committee of the 16th Naples Workshop on Bioactive Peptides, Naples (Italy) June 7-9, 2018.

2017: Appointed member of the Advisory Committee of the American Peptide Symposium 2019, Monterey, CA, USA, June 22-27, 2019.

2017: Appointed member of the Organising Committee of the European Chemistry Conference, Roma (Italy) June 11-13, 2018.

Member of the scientific committees of European Peptide Symposia: 2016: 34th European Peptide Symposium, Leipzig (Germany); 2014: 33rd European Peptide Symposium, Sofia (Bulgaria), 2010: 31st European Peptide Symposium, Copenhagen (Denmark).

2009: Member of the scientific committee of SCS-09 - 2nd International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials, Bejing (China).

2002 and 2004: Member of the scientific committee of 2nd, 3^rd, and 5th Medicinal Chemistry Conference: Drug discovery and Design, University of Patras (Greece).

Member of international evaluations and selection committees of PhD and habilitation exams

2021: Rapporteur of the PhD Committee of Carole Deflers, July 8, 2021, Title: Evaluation and Optimization of Targeting Systems for the Preferential Heart Delivery of Therapeutic Agents. PhD thesis of the Université Paris-Saclay, École doctorale n°569 : Innovation Thérapeutique : du fondamental à l’appliqué (ITFA).

2021: Member of the PhD Committee of Hendrik Rusche as Supervisor, April 12, 2021, Ecole Doctorale Sciences et Techniques, CY Cergy Paris Université (online via Zoom)

2020: Examinateur of the PhD Committee of Bastien Petit, December 2, 2020, Ecole Doctorale de Pharmacie, Université de Bourgogne Franche-Comté (online via Zoom)

2020: Member of the PhD Committee of Antonio Mazzoleni as Supervisor, May 5, 2020, Ecole Doctorale en Chimie, Paris Sorbonne Université (online via Zoom)

August-September 2018: Member of the selection committee of the 34th PhD Course in Chemical Sciences of the University of Florence (Italy).

2010, 2012 & 2013: Referee at Ecole Doctorale en Chimie, Université Pierre et Marie Curie, Paris (France)

2010: Referee for the Ecole Doctorale en Chimie, Université Montpellier (France)

2009 : Referee for the Ecole Doctorale en Chimie, Université de Bourgogne (France)

2008, 2010 & 2011 : Referee for the Ecole Doctorale en Chimie, Université de Strasbourg (France)

2011, 2016 & 2016 : Referee for the Ecole Doctorale en Chimie, Université Paris-Sud (France)

2012: Referee for the PhD School in Chemistry of the University of Montreal (Canada).

Referee of “Habilitations à diriger les recherches” (HDR)

2008: University of Strasbourg (France)

2011: Université Pierre et Marie Curie, Paris (France).

Activities as Visiting Professor/Scientist

2020: Staff Teaching Mobility, Université de Rouen (8h teaching)

2019: Erasmus Teaching Mobility at the University of Wroclaw (Poland) (13h teaching – 1 week)

2018: Erasmus Teaching Mobility at the University of Wroclaw (Poland) (13h teaching – 1 week)

2016: Erasmus Teaching Mobility at the University of Wroclaw (Poland) (10h teaching – 1 week)

2010: Erasmus Teaching Mobility at the University of Bolu (Turkey) (8h teaching – 1 week)

2010: Erasmus Teaching Mobility at the University of Balikesir (Turkey) (8h teaching – 1 week)

2010: Erasmus Teaching Mobility at the University of Patras (Greece) (8h teaching – 1 week)

2010: Erasmus Teaching Mobility at the University of Gdansk (Poland) (8h teaching – 1 week)

2008: Invited Professor at the Université de Cergy-Pontoise (France) (8h teaching – 1 week)

2008: Invited Professor at the Université de Bourgogne, Dijon (France) (1 month)

2005: Invited Professor of Organic Chemistry at the Université de Bourgogne, Dijon (France) (1 month)

1999: Visiting Scientist at the Medizinisch Naturwissenschaftlichens Forschungs Zentrum, University of Tuebingen (Germany) (1 month)

1999: Invited Professor of Organic Chemistry, U.F.R. Sciences et Techniques, Neuville sur Oise, Université de Cergy-Pontoise (France) (1 month)

1998: Invited Professor of Organic Chemistry, U.F.R. Sciences et Techniques, Neuville sur Oise, Université de Cergy-Pontoise (France) (6 months).

Teaching activities at the School of Mathematical, Physical, and Natural Sciences, Department of Chemistry, University of Florence (Italy)

Since 2019-2020: Master Course in English in Advanced Molecular Sciences: Course Advanced synthetic methods (6 ECTS).

Since 2010: “Laurea Magistrale” (M.Sc.) in Chemical Sciences: curriculum in Chemistry of Biological Molecules: Course Chemistry of Biomolecules (6 ECTS); curriculum in Synthesis and reactivity of organic molecules, Course Bioorganic Chemistry (6 ECTS).

2002-2007: “Laurea triennale” (B.Sc.) in Chemistry (6 ECTS): Course Laboratory of Organic Chemistry I.

2007-2009: “Laurea Specialistica” (M.Sc.) in Chemistry of Biological Molecules: Course Bioorganic Chemistry & Laboratory of Bioorganic Chemistry (6 ECTS).

Teaching activities at the UFR Sciences et Techniques, University of Cergy-Pontoise (France)

2009-2014: 60h/year Semester 1: Bioorganic Chemistry (20h: 10h CM + 10h TD); Travaux Pratiques Chimie organique (35h).

2015-2020: 132h/year. Semester 1, Course Master 1: Bioorganic Chemistry (20h: 10h CM + 10h TD), Course Master 2 Molecules for health: Peptides and Proteins (15h CM) and Immunochemistry (6h CM). Semester 2, Course Master 1 – option biomolecules: Amino acids and peptides (20h: 10h CM + 10h TD); Practical tutorials (Travaux Pratiques) Organic Chemistry (35h). Direction of the platform PeptLab@UCP: 24h.

Innovative Teaching and Dissemination Activities in Italy

2016-2021: Coordinator with Prof. V. Schettino of the Training course for professors of Sciences Multidisciplinary aspects of teaching Sciences in high schools, Polo Firenze - I Lincei per una nuova didattica nella Scuola, Fondazione “I Lincei per la Scuola”, Accademia Nazionale dei Lincei.

2020: Panel member of the evaluation committee of the finalists of FameLab 2020 (March 7, 2020): “Talent in science” an international competition of young researchers and PhD students involved in scientific dissemination, OpenLab, Psiquadro, and British Council Italy (the first 2 will participate at Masterclass in science communication at the international competition in Cheltenham, UK, June 4-5, 2020.

2010-2012: Director of the “Corso di Specializzazione per la Professione di Chimico”, Faculty of Sciences of the University of Florence in cooperation with Ordine dei Chimici della Toscana.

2010 and 2011: Organiser of the Course “Rischio Chimico” for VVFF (Vigili del Fuoco) in the Regione Toscana in cooperation with OpenLab and Ordine dei Chimici della Toscana

2010: Organiser of the Course “Mass Spectrometry” for VVFF (Vigili del Fuoco) in the Regione Toscana in cooperation with OpenLab and Ordine dei Chimici della Toscana.

2002-2003: Member of the Board and teaching activity in the Master 2nd level “Innovative Synthetic Methodologies” of the Faculty of Sciences of the University of Florence.

2002: Member of the Organising Board of the Open day of the Department of Chemistry XII Week of Scientific Culture in Tuscany.

Since 2001: Organiser of Chemistry Activities for OpenLab – Dissemination of Science at the “Polo Scientifico e Tecnologico” of the University of Florence for students from 3 to 18 years old of the Schools in Tuscany.

1986-1990: Trainer of Chemistry for Teachers of Primary Schools in the Project IRRSAE in Tuscany.

Scientific contributions

1. www.peptlab.eu

BIBLIOMETRIC PARAMETERS. WOS data (26/06/2021). Number of publications: 318. h-index: 30. Total citations: 2884. http://orcid.org/0000-0002-2947-7107

Communication of the scientific activity

2000-2021: invited to present 128 lectures: 101 lectures in International Symposia (keynotes, invited and plenary), Universities and Research Centres (EU, USA, Canada, Australia, Israel, Japan, South Korea, China) and 27 lectures aimed to technology transfer in the global space of R&D. 1997-2021: 66 oral & 253 poster communications were selected in international symposia and presented by her students or co-workers or personally.

Supervisor of diploma/master/bachelor and PhD students

Supervisor of 26 PhD students in Chemical Sciences (23 finalised and 3 ongoing), 59 M.Sc. in Chemical Sciences (55 finalised and 4 ongoing), 28 B.Sc. (26 finalised and 2 ongoing). Tutor of Erasmus students: 31 Erasmus Traineeship students for periods from 4 months till 1 year (29 finalised, 2 ongoing).

Snap-shot of the group (as of June 2021)

3 PhDs; 5 Post-docs; 1 CNR Researcher; 3 Technologists, 1 Full Professor, 2 Associate Professors; 6 M.Sc. and B.Sc. students; 2 Erasmus traineeship students.

Editorial Advisory Board Member

Since 2005: Editor-for-Europe of Protein & Peptide Letters, Bentham Science Publishers Ltd.

Since 2004: Current Drug Delivery, Bentham Science Publishers Ltd.

Since 2005: International Journal of Peptide Research and Therapeutics.

Since 2009: Member of the Editorial Advisory Board of Journal of Peptide Science, Wiley Publisher.

Since 2013: Member of the Editorial Advisory Board of Current Protein & Peptide Science, Bentham Science Publishers Ltd.

Since 2003: Member of the Editorial Advisory Board of International Journal of Peptide Research and Therapeutics, Springer

Since 2017: Member of the Editorial Board di Biosensors – Open Access Jounal MDPI (ISSN 2079-6374; CODEN: BIOSHU

Since 2018: Review Editor of Frontiers in Chemistry – Chemical Biology Open access publisher

Since 2018: Associate Editor of Current Peptide and Protein Sciences, Bentham Science Publishers Ltd.

2007-2016: Member of the Editorial Board of Chemistry Today, Editor Teknoscienze

Member of the board of scientific societies

2019-2025: Elected Councilor of the American Peptide Society.

2011-2020: Elected Treasurer and member of the Executive Board of the European Peptide Society. She contributed to an increase of funding from 97.000,00 Euro to 250.000,00 Euro thanks to new agreements established with Wiley, BCN, Curran Associates.

2017-2021: Elected Member of the Executive Board of the Italian Peptide Society and acting as scientific officer.

2004-2008: Appointed Member of the Scientific Affairs Committee of the European Peptide Society.

2000-2013: Appointed academic representative for Italy in the Board of the Society of Combinatorial Chemistry.

Scientific Societies Membership

Since 1988: Charter Member of the American Peptide Society.

Since 1988: Member of the European Peptide Society and of the Federation of American Societies for Experimental Biology.

Since 2000: Member of the Society of Combinatorial Sciences.

Since 1993: Charter Member of the Division of Chemistry of Biological Systems of the Italian Society of Chemistry.

Since 2016: Founder and member of the Italian Peptide Society

Scientific fields of interest

Peptide and protein organic chemistry. Development of synthetic solid-phase strategies. Microwave-assisted peptide synthesis. Bioorganic chemistry of peptides and proteins. Synthetic & semi-synthetic strategies of co- or post-translationally modified proteins. Unnatural amino acids orthogonally protected for peptide synthesis (constrained amino acids, glycosyl and lipophilic amino acids). Coupling reagents for peptide chemistry (amide and ester bond formation). Side-chain to side-chain peptide cyclisation, i.e., lactams, dicarba analogs, triazolyl-based cyclization, Glaser cyclization, etc., to mimic bioactive secondary structures for SAR studies (PTH, MT, Octreotide, Oxytocin, etc.)

Chemical immunology. Characterization of aberrant post-translational modifications (glycosylation, glycation, lipoylation, etc.) in antigens triggering immune-mediated diseases (Multiple Sclerosis, T1D, PBC, coeliac disease, rheumatoid arthritis, Rett Syndrome, Metabolic disorders, etc.) to characterize antibodies. Characterization of anti-drug antibodies. Study of the molecular mechanisms of immune-mediated diseases. Cross-reactions with infectious diseases, i.e., bacterial and/or viral infections.

Industrial applications

In vitro Diagnostics and peptide biomarkers. Glycoconjugates and PTM antigens as diagnostic and prognostic tools for human, animal, and plant diseases. IVDs for autoimmune diseases. Characterisation of biomarkers of disease activity. R&D of diagnostic/prognostic tools, immunotherapies, apheresis technologies. In vivo Diagnostics and imaging techniques. DOTA peptide analogues for cancer pre-targeting diagnosis & therapy. FIV peptides for the development of an anti-retroviral therapy for felines. Cultural heritage. Peptide-based immunoassays for characterization of glues, in particular collagen. Peptide Nutraceuticals and cosmeceuticals. Spiruline. Fish feed. Peptides involved in collagen turnover. Development of processes for large-scale solid-phase peptide synthesis. Production of active pharmaceutical peptide ingredients by MW-technology.

Anna Maria Papini was born in Firenze (Italy) on February 2, 1959. Married with 2 daughters Giulia (born in 1991) and Elena (born in 1996). French and Italian nationality. Bilingual: French and Italian mother tongues. Language skills: English and German.

Prof. Anna Maria Papini, PhD ORCID: 0000-0002-2947-7107

PUBLICATIONS IN PEER-REVIEWED SCIENTIFIC JOURNALS (1983-2021)

[1] M. Taddei, A.M. Papini, M. Fiorenza, A. Ricci, G. Seconi. Ring opening reactions of thiiranes with group IVB organometallics: a new regioselective route to b-amino and b-cyanide thiols. Tetrahedron Lett 1983; 24(22), 2311-2314. DOI: 10.1016/S0040-4039(00)81911-5

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, MAY 1983.

[2] A.M. Papini, A. Ricci, M. Taddei, G. Seconi and P. Dembech. Regiospecific Conversion of Oxiranes, Oxetanes, and Lactones into Difunctional Nitrogen Compounds via Aminosilanes and Aminostannanes. J Chem Soc Perkin Trans I 1984; 2261-2265. ISSN: 14727781

Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, OCTOBER 1984.

[3] S. Francalanci, S. Giorgini, M. Gola, M. Ginanneschi, A.M. Papini and A. Sertoli. Eczema da contatto da antifungino topico. Boll. Dermatol. Allergol. e professionale (1986) 1, 9-13.

[4] M. Ginanneschi, A. Sertoli, A.M. Papini, G. Rapi. Chemical aspects of hapten-carrier interaction in contact allergy. Giorn It Derm Vener 1987; 122(7-8), 389-395. PubMed ID 3666799. ISSN: 00264741

Published by EDIZIONI MINERVA MEDICA, TORINO, ITALY, JULY-AUGUST 1987

[5] S. Giuliani, R. Amann, A.M. Papini, C.A. Maggi, A. Meli. Modulatory action of galanin on responses due to antidromic activation of peripheral terminals of capsaicin-sensitive sensory nerves. Eur J Pharmacol 1989; 163(1), 91-96. DOI: 101016/0014-2999(89)90399-3

Published by ELSEVIER, Amsterdam, THE NETHERLANDS, APRIL 1989.

[6] M. Ginanneschi, M. Chelli, A.M. Papini, G. Rapi. Highly efficient synthesis of steroid-17-spiro-5’-oxazolidine-2’,4’-diones from 17-keto steroids. Steroids 1990; 55(11), 501-506. DOI:10.1016/0039-128X(90)90088-S

Published by ELSEVIER, STONEHAM, MA, USA, NOVEMBER 1990.

[7] M. Chelli, G. Dupuis, S. Evangelista, M. Ginanneschi, A. Meli, A.M. Papini, G. Rapi. Suppression of the skin response to alantolactone in alantolactone-sensitized guinea pigs treated with N-acetyl-l-cysteinyl-l-alanine methyl ester. Eur J Med Chem 1990; 25(2), 107-115. DOI: 10.1016/0223-5234(90)90017-W

Published by ELSEVIER, PARIS, FRANCE, MARCH 1990.

1991-1998

[8] R. von Grünigen, G. Siglmüller, A.M. Papini, K. Köcher, B. Traving, W. Göhring, L. Moroder. Enzyme Immunoassay with Captured Hapten. A sensitive Gastrin Assay with Biotinyl-Gastrin Derivatives. Biol Chem Hoppe-Seyler 1991; 372(3), 163-172. DOI: 10.1515/bchm3.1991.372.1.163

Published by DE GRUYTER, BERLIN, GERMANY, MARCH 1991.

[9] A.M. Papini, S. Rudolph, G. Siglmüller, H.-J. Musiol, W. Göhring, L. Moroder. Alkylation of histidine with maleimido-compounds. Int J Pept Prot Res 1992; 39(4), 348-355. DOI: 10.1111/j.1399-3011.1992.tb01594.x

Published by WILEY, COPENHAGEN, DENMARK, APRIL 1992.

[10] D. Donati, M. Ginanneschi, M. Chelli, G. Rapi, A.M. Papini. X-ray structure analysis of 3,11,17-trioxoandrostane-5a-carbonitrile and of 17a-ethoxycarbonyloxy-3-oxoandrost-4-ene-17-carbonitrile. Steroids 1992; 57(10), 502-506. DOI: 10.1016/0039-128X(92)90045-B

Published by ELSEVIER, STONEHAM, MA, USA, OCTOBER 1992.

[11] L. Moroder, A.M. Papini, G. Siglmüller, K. Köcher, E. Dörrer, C.H. Schneider. Induction and Detection of anti-peptide antibody specificity is critically affected by the mode of hapten presentation. Biol Chem Hoppe-Seyler 1992; 373(6), 315-321. DOI: 10.1515/bchm3.1992.373.315

Published by DE GRUYTER, BERLIN, GERMANY, JUNE 1992.

[12] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi. Cyclization of C-Terminal Histidine Peptides to 7-Amino-dihydroimidazo[1,5-c]pyrimidin-5-one Derivatives. J Chem Research - S 1993; 3:118-119.

Pubblicato Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, MARCH 1993.

[13] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi, E. Borghi, F. Laschi, M. Occhiuzzi. Complexation properties of Histidyl-Glycyl-containing peptides. Part 1. Synthesis of cyclo(L-His-Gly)4^. J Chem Research - S 1993; 11:437-437 and J Chem Res - M 1993; 11:2929-2938.

Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, NOVEMBER 1993.

[14] E. Borghi, F. Laschi, M. Occhiuzzi, M. Chelli, M. Ginanneschi, A.M. Papini; G. Rapi. Complexation properties of Histidyl-Glycyl containing peptides. Part 2. An X-band EPR study of divalent paramagnetic metal ions interacting in solution with H-(L-His-Gly)2-OMe. J Chem Research - S 1994; 1:48-49.

Published by ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, ENGLAND, JANUARY 1994.

[15] D. Pinzani, A.M. Papini, M. Chelli, M. Ginanneschi, C.A. Maggi, R. Patacchini, L. Quartara; G. Rapi. Synthesis and biological activity of tachykinin analogs containing the adamantane moiety. Lett Pept Sci 1996; 2(5), 307-313. DOI: 10.1007/BF00142244

Published by SPRINGER VERLAG, LEIDEN, THE NETHERLAND, FEBRUARY 1996

[16] M. Ginanneschi, M. Chelli, A.M. Papini, D. Pinzani; G. Rapi. Structure of the adduct of Alantolactone with Z-l-Cys-l-Ala-OMe and 1H and 13C assignment of the Alantolactone moiety by 14 Tesla NMR. Magn Reson Chem 1996; 34(2), 95-99. DOI: 10.1002/(SICI)1097-458X(199602)34

Published by WILEY, CHICHESTER, W. SUSSEX, ENGLAND, FEBRUARY 1996.

[17] D. Pinzani, A.M. Papini, M.E. Vallecchi, M. Chelli, M. Ginanneschi, G. Rapi, L. Quartara, R. Patacchini, C.A. Maggi, F.M. Arcamone. Glycosyl derivatives of NK2 tachykinin receptor antagonists. Bioorg Med Chem Lett1996; 6(4), 367-372. DOI: 10.1016/0960-894X(96)00039-X

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, FEBRUARY 1996

[18] G. Giorgi, M. Ginanneschi, M. Chelli, A.M. Papini, F. Laschi, E. Borghi. Histidyl-Glycyl containing peptides. Characterization and complexation properties of H(L-His-Gly)₂-R with hydrogen and alkali metal ions in the gas-phase. Rapid Commun Mass Spectrom 1996; 10(10), 1266-1272. DOI: 10.1002/(SICI)1097-0231(19960731)10

Published by WILEY, CHICHESTER, W. SUSSEX, ENGLAND, OCTOBER 1996.

[19] G. Caminati, A.M. Papini, S. Mazzucco, G. Gabrielli. Lipopeptides of myelin basic protein in mono- and multilayers. Thin Solid Films 1998; 327:37-41. DOI: 10.1016/S0040-6090(98)00583-5

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 31 AUGUST 1998.

[20] M. Ciuffi, C. Cellai, S. Franchi-Micheli, P. Failli, L. Zilletti, M. Ginanneschi, M. Chelli, A.M. Papini; F. Paoletti. An in vivo, ex vivo and in vitro comparative study of activity of copper oligopeptide complexes vs Cu(II) ions. Pharmacol Res 1998; 38(4), 279-287. DOI: 10.1006/phrs.1998.0369

Published byPERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, FEBRUARY 1998.

1999

[21] S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, G. Rapi, A.M. Papini, M. Vergelli, B. Mazzanti, L. Massacesi, L. Amaducci. Synthesis of lipopeptides of the immunodominant epitope hMBP(83-99) containing amide or C-C bond linked hydrophobic chains for the study of T cell response. Lett Pept Sci 1999; 6(1), 51-59. DOI: 10.1007/BF02443618

Published by SPRINGER VERLAG, DORDRECH, THE NETHERLAND, JANUARY 1999.

[22] G. Sabatino, M. Chelli, S. Mazzucco, M. Ginanneschi, A.M. Papini. Cyclisation of Histidine Containing Peptides in the Solid-Phase by Anchoring the Imidazole Ring to Trityl Resins. Tetrahedron Lett 1999; 40(4), 809-812. DOI: 10.1016/S0040-4039(98)02459-9

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, JANUARY 1999.

[23] S. Mazzucco, S. Matà, M. Vergelli, R. Fioresi, E. Nardi, B. Mazzanti, M. Chelli, F. Lolli, M. Ginanneschi, F. Pinto, L. Massacesi, A.M. Papini. A synthetic glycopeptide of human Myelin Oligodendrocyte Glycoprotein to detect antibody responses in Multiple Sclerosis and other neurological diseases. Bioorg Med Chem Lett 1999; 9(2), 167-172. DOI: 10.1016/S0960-894X(98)00698-2

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, JANUARY 1999.

[24] M. Casolaro, M. Chelli, M. Ginanneschi, F. Laschi, M. Muniz-Miranda, A.M. Papini, G. Sbrana. Spectroscopic and potentiometric study of copper(ii) complexes with l-histidyl-glycyl-l-histidyl-glycine in aqueous solution. Spectrochimica Acta Part A, Mol & Biomol Spectroscopy 1999; 55(7-8), 1675-1689. DOI: 10.1016/S1386-1425(98)00328-X

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, JULY-AUGUST 1999.

[25] C. Galoppini, S. Meini, M. Tancredi, A. Di Fenza, A. Triolo, L. Quartara, C.A. Maggi, F. Formaggio, C. Toniolo, S. Mazzucco, A.M. Papini, P. Rovero. A new class of pseudopeptide antagonists of the kinin B1 receptor containing alkyl spacers. J Med Chem 1999; 42(3), 409-414. DOI: 10.1021/jm980495r

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 11 FEBRUARY 1999.

2001

[26] C. Giragossian, E. Nardi, C. Savery, M. Pellegrini, S. Meini, C.A. Maggi, A.M. Papini, D. Mierke. Structural characterization of lipopeptide agonists for the Bradykinin B2 receptor. Biopolymers 2001; 58(5), 511-520. DOI: 10.1002/1097-0282(20010415)58

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 20 FEBRUARY 2001

[27] A.M. Papini, B. Mazzanti, E. Nardi, E. Traggiai, C. Ballerini, T. Biagioli, H. Kalbacher, H. Beck, M. Deeg, M. Chelli, M. Ginanneschi, L. Massacesi, M. Vergelli. Palmitoyl Derivatives of GpMBP Epitopes: T-Cell Response and Peptidases Susceptibility. J Med Chem 2001; 44(21), 3504-3510. DOI: 10.1021/jm010913j

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, SEPTEMBER 13, 2001

[28] F. Meyer, J. Uziel, A.M. Papini, S. Jugé. Triphenylphosphonium salts bearing an l-alanyl substituents: short synthesis and enantiomeric analysis by NMR. Tetrahedron Lett 2001; 42(24), 3981-3984. DOI: 10.1016/S0040-4039(01)00650-5

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 11 JUNE 2001

[29] A. Carotenuto, A.M. D’Ursi, E. Nardi, A.M. Papini, P. Rovero. Conformational analysis of a glycosylated Human Oligodendrocyte Glycoprotein peptide epitope able to detect antibody response in Multiple Sclerosis. J Med Chem 2001; 44(14), 2378-2381. DOI: 10.1021/jm010811t

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, JUNE 7, 2001

2002

[30] E. Peroni, G. Caminati, P. Baglioni, F. Nuti, M. Chelli,A.M. Papini. A New lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models. Bioorg Med Chem Lett2002; 12(13), 1731-1734. DOI: 10.1016/S0960-894X(02)00253-6

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 8 JULY 2002

[31] M. Casolaro, M. Chelli, M. Ginanneschi, F. Laschi, L. Messori, M. Muniz-Miranda, A.M. Papini, T. Kowalik-Jankowska, H. Kozlowski. Spectroscopic and potentiometric study of the SOD mimic system Copper/Acetyl-L-histidyl-glycyl-L-histidyl-glycine. J Inorganic Biochem 2002; 89(3-4), 181-190. DOI: 10.1016/S0162-0134(02)00365-3

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, 1 APRIL 2002

[32] A.M. Papini,E. Nardi, F. Nuti, J. Uziel, M. Ginanneschi, M. Chelli, A. Brandi. Diastereoselective alkylation of Schiff bases for the synthesis of lipidic unnatural Fmoc-protected a-amino acids. Eur J Org Chem2002; 16, 2736-2741. DOI: 10.1002/1099-0690(200208)2002:16<2736

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, 19 JULY 2002

[33] C. Giragossian, S. Stone, A.M. Papini, L. Moroder, D.F. Mierke. Conformational and molecular modeling studies of sulfated cholecystokinin-15. Biochem Biophys Res Commun 2002; 293(3), 1053-1059. DOI: 10.1016/S0006-291X(02)00334-0

Published by ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 1 MAY 2002

[34] G. Sabatino, B. Mulinacci, M.C. Alcaro, M. Chelli, P. Rovero, A.M. Papini. Assessment of new 6Cl-HOBt based coupling reagents for peptide synthesis. Part 1: Coupling efficiency study. Lett Pept Sci 2002; 9(2-3), 119-123. DOI: 10.1007/BF02576873

Published by SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, MARCH 2002

2003

[35] G. Sabatino, M. Chinol, G. Paganelli, S. Papi, M. Chelli, G. Leone, A.M. Papini, A. De Luca, M. Ginanneschi. ANew Biotin Derivative-DOTA Conjugate as a candidate for pre-targeted diagnosis and therapy of tumors. J Med Chem2003; 46(14):3170-3173. DOI: 10.1021/jm030789z

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, JUNE 5, 2003

[36] M.C. Alcaro, M. Orfei, M. Chelli, M. Ginanneschi, A.M. Papini. Solid-phase approach to the synthesis of cyclen derivatives from cyclotetrapeptides. Tetrahedron Letters 2003; 44(28):5217-5219. DOI: 10.1016/S0040-4039(03)01213-9

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 7 JULY 2003

[37] F. Meyer, A. Laaziri,A.M. Papini, J. Uziel, S. Jugé. Efficient synthesis of b-halogeno protected L-alanines and their b-phosphonium derivatives. Tetrahedron Asymmetry 2003; 14(15):2229-2238. DOI: 10.1016/S0957-4166(03)00484-1

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 1 AUGUST 2003

[38] M.C. Alcaro, E. Peroni, P. Rovero, A.M. Papini. Synthetic peptides in the diagnosis of HIV infection. REVIEW. Current Protein and Peptide Science 2003; 4(4):285-290. DOI: 10.2174/1389203033487117

Published byBENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2003

[39] F. Lolli, B. Mazzanti, P. Rovero, A.M. Papini. Synthetic peptides in the diagnosis of neurological diseases. REVIEW. Current Protein and Peptide Science2003; 4(4):277-284. DOI: 10.2174/1389203033487162

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2003

IF: 2,696 - Citations: 3 (Scopus); 1 (WoS).

2004

[40] M.C. Alcaro, G. Sabatino, J. Uziel, M. Chelli, M. Ginanneschi, P. Rovero, A.M. Papini.On-resin head-to-tail cyclization of cyclotetrapeptides: optimization of crucial parameters. J Pept Sci 2004; 10(4), 218-228. DOI: 10.1002/psc.512.

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 10 NOVEMBER 2003

[41] F. Meyer, A. Laaziri,A.M. Papini, J. Uziel, S. Jugé. A novel phosphorus-carbon bond formation by ring opening with diethyl phosphite of oxazolines derived from serine. Tedrahedron 2004; 60(16), 3593-3597. DOI: 10.1016/j.tet.2004.03.001

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 12 APRIL 2004

[42] F. Machetti, F.M. Cordero, F. De Sarlo, A.M. Papini, M.C. Alcaro, A. Brandi. Synthesis of free and N^a-Fmoc/N^a-Boc protected (2S, 4S)- and (2S, 4R)-4-aminopipecolic acids. Eur J Org Chem 2004; 13, 2928-2935. DOI: 10.1002/ejoc.200400045

Published by WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, 15 JUNE 2004

[43] A. Innocenti, A. Casini, M.C. Alcaro, A.M. Papini, A. Scozzafava,C.T. Supuran. Carbonic anhydrase inhibitors: The first on-resin screening of a 4-sulfamoylphenylthioureas library. J Med Chem 2004; 47(21), 5224-5229. DOI: 10.1021/jm049692i.

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 25, 2004

[44] G. Caminati, E. Peroni, A.M. Papini, P. Baglioni. Photophysical investigation of lipopeptides of myelin basic protein in phospholipid vesicles. Progress in Colloid & Polymer Science 2004; 126, 163-168. DOI: 10.1007/b93987

Published by SPRINGER-VERLAG BERLIN, HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY, OCTOBER 2004

[45] G. Sabatino, M. Chelli, A. Brandi, A.M. Papini.Analytical methods for solid phase peptide synthesis. Current Organic Chemistry 2004; 8(4), 291-301. DOI: 10.2174/1385272043485954

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2004

2005

[46] A. Carotenuto, D. D’Addona, E. Rivalta, M. Chelli, A.M. Papini, P. Rovero, M. Ginanneschi. Synthesis of a dicarba-analogue of octreotide keeping the type II’ b-turn of the pharmacophore in water solution. Lett Org Chem 2005; 2(3), 274-279. DOI: 10.2174/1570178053765276

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2005

[47] J. Matsoukas, V. Apostolopoulos, H. Kalbacher, A.M. Papini, T. Tselios, K. Chatzantoni, T. Biagioli, F. Lolli, S. Deraos, P. Papathanassopoulos, A. Troganis, E. Mantzourani, T. Mavromoustakos, A. Mouzaki. Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators. J Med Chem 2005; 48(5), 1470-1480. DOI: 10.1021/jm040849g

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, FEBRUARY 15, 2005

 [48] F. Nuti, S. Hildenbrand, M. Chelli, R. Wodarzb, A.M. Papini.Synthesis of DEHP metabolites as biomarkers for GC-MS evaluation of phthalates as endocrine disrupters. Bioorg Med Chem 2005; 13(10), 3461-3465. DOI: 10.1016/j.bmc.2005.03.005

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 1 MAY 2005

[49] A.M. Papini. Simple test for Multiple Sclerosis. Nature Medicine2005; 11(1), 13. DOI: 10.1038/nm0105-13

Published by NATURE PUBLISHING GROUP, 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA, 1 JANUARY 2005

[50] Lolli F, Mulinacci B, Carotenuto A, Bonetti B, Sabatino G, Mazzanti B, D'Ursi AM, Novellino E, Pazzagli M, Lovato L, Alcaro MC, Peroni E, Pozo-Carrero MC, Nuti F, Battistini L, Borsellino G, Chelli M, Rovero P, Papini AM. An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis. Proc Natl Acad Sci USA 2005; 102(29):10273-10278. DOI: 10.1073/pnas.0503178102

Published by NATL ACAD SCIENCES, 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA, 19 JULY, 2005

[51] F. Lolli, B. Mazzanti, M. Pazzagli, E. Peroni, M.C. Alcaro, R. Lanzillo, V. Brescia Morra, L. Santoro, C. Gasperini, S. Galgani, M.M. D’ Elios, V. Zipoli, S. Sotgiu, M. Pugliatti, P. Rovero, M. Chelli, A.M. Papini.The glycopeptide CSF114(Glc) detects serum antibodies in Multiple Sclerosis. J Neuroimmunol 2005; 167(1-2), 131-137. DOI: 10.1016/j.jneuroim.2005.05.016

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, OCTOBER 2005

[52] S. Giannecchini, M.C. Alcaro, P. Isola, O. Sichi, M. Pistello, A.M. Papini, P. Rovero, M. Bendinelli. Feline immunodeficiency virus plasma load reduction by a retroinverso octapeptide reproducing the Trp-rich motif of the transmembrane glycoprotein. Antiviral Therapy 2005; 10(5), 671-680.

Published by INT MEDICAL PRESS LTD, 2-4 IDOL LANE, LONDON EC3R 5DD, ENGLAND, 1 JANUARY 2005

[53] F. Lolli, P. Rovero, M. Chelli, A.M. Papini.Antibodies against glycosylated native MOG are elevated in patients with Multiple Sclerosis. Neurology 2005 65(5), 781-782.

LIPPINCOTT WILLIAMS & WILKINS, TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA, SEPTEMBER 13, 2005

[54] Kamiński ZJ, Kolesińska B, Kolesińska J, Sabatino G, Chelli M, Rovero P, Błaszczyk M, Główka ML, Papini AM. N-triazinylammonium tetrafluoroborates. A new generation of efficient coupling reagents useful for peptide synthesis. J Am Chem Soc 2005; 127(48):16912-16920. DOI: 10.1021/ja054260y

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, NOVEMBER 10, 2005

2006

[55] F. Minutolo, S. Bertini, L. Betti, R. Danesi, G. Gervasi, G. Giannaccini, A. Martinelli, A.M. Papini, E. Peroni, G. Placanica, S. Rapposelli, T. Tuccinardi, M. Macchia. Synthesis of stable snalogues of geranylgeranyl Diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition. CHEMMEDCHEM 2006; 1(2), 218-224.  DOI: 10.1002/cmdc.200500010

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, FEBRUARY 2006

[56] A.M. D’Ursi, S. Giannecchini, C. Esposito, M.C. Alcaro, O. Sichi, M.R. Armenante, A. Carotenuto, A.M. Papini, M. Bendinelli, P. Rovero. Development of antiviral fusion inhibitors: short modified peptides derived from the transmembrane glycoprotein of feline immunodeficiency virus. CHEMBIOCHEM 2006; 7(5), 774-779. DOI: 10.1002/cbic.200500390

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MAY 2006

[57] Alcaro MC, Vinci V, D'Ursi AM, Scrima M, Chelli M, Giuliani S, Meini S, Di Giacomo M, Colombo L, Papini AM. Bradykinin antagonists modified with dipeptide mimetic beta-turn inducers. Bioorg Med Chem Lett 2006; 16(9):2387-2390. DOI: 10.1016/j.bmcl.2006.01.125

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 28 FEBRUARY 2006

[58] M.C. Alcaro, A.M. Papini. Contribution of peptides to Multiple Sclerosis research. Biopolymers 2006; 84(4), 349-367. DOI: 10.1002/bip.20498

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2006

[59] V.V. Volkov, F. Nuti, Y. Takaoka, R. Chelli, A.M. Papini, R. Righini. Hydration and hydrogen bonding of carbonyls in dimyristoyl-phospahtidylcholine bilayer. J Am Chem Soc2006; 128(29), 9466-9471. DOI: 10.1021/ja0614621

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, JULY 26, 2006

[60] A. Carotenuto, A.M. D’Ursi, B. Mulinacci, I. Paolini, F. Lolli, A.M. Papini, E. Novellino, P. Rovero. Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J Med Chem 2006; 49(17), 5072-5079. DOI: 10.1021/jm060117j

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 24, 2006

[61] F. Lolli, P. Rovero, M. Chelli, A.M. Papini. Toward biomarkers in multiple sclerosis: new advances. Expert Review Neurotherapeutics 2006; 6(5), 781-794. DOI: 10.1586/14737175.6.5.781

Published by TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND, MAY 2006

2007

[62] Rizzolo F, Sabatino G, Chelli M, Rovero P, Papini AM. A convenient microwave-enhanced solid-phase synthesis of difficult peptide sequences: case study of Gramicidin A and CSF114(Glc). Int J Pept Res Ther 2007; 13(1-2), 203-208. DOI:10.1007/s10989-006-9066-8

Published by SPRINGER, 233 SPRING STREET, NEW YORK, NY 10013 USA, JUNE 2007

[63] K. Jastrząbek, B. Kolesińska, G. Sabatino, F. Rizzolo, A.M. Papini, Z.J. Kamiński. Benzyloxy derivatives of triazine-based coupling reagents designed for an efficient solid phase peptide synthesis on polystyrene resin. Int J Pept Res Ther 2007; 13(1-2), 229-236. DOI: 10.1007/s10989-006-9071-y

Published by SPRINGER, 233 SPRING STREET, NEW YORK, NY 10013 USA, JUNE 2007

[64] B. Kolesińska, J. Frączyk, G. Sabatino, A.M. Papini, Z.J. Kamiński. Sulfonates of N-triazinylammonium salts as highly efficient, inexpensive and environmentally friendly coupling reagents for peptide synthesis. Chimica oggi-Chemistry Today 2007; 25(1), 10-13.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, in 2007

[65] I. Paolini, F. Nuti, M.C. Pozo-Carrero, F. Barbetti, B. Kolesinska, Z.J. Kaminski, M. Chelli, A.M. Papini. A convenient microwave-assisted synthesis of N-glycosyl amino acids. Tetrahedron Letters 2007; 48(16), 2901-2904. DOI: 10.1016/j.tetlett.2007.02.087

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 16 APRIL 2007 (online 22 FEBRUARY 2007)

[66] F. Nuti, I. Paolini, F. Cardona, M. Chelli, F. Lolli, A. Brandi, A. Goti, P. Rovero, A.M. Papini. Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides. Bioorg Med Chem 2007; 15(12), 3965-3973.

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 15 JUNE 2007

[67] M.C. Alcaro, F. Lolli, P. Migliorini, M. Chelli, P. Rovero, A.M. Papini. Peptides as autoimmune diseases antigenic probes: a peptide-based reverse approach to detect biomarkers of autoimmune diseases. Chimica oggi-Chemistry Today 2007; 25(3S), 14-16.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, in 2007

[68] V.V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A.M. Papini, S. Mukamel, R. Righini. Electrostatic interactions in phospholipid membranes revealed by coherent two-dimensional infrared spectroscopy. Proc Natl Acad. Sci, USA 2007; 104(39):15323-15327. DOI:  10.1073/pnas.0706426104

Published by NATL ACAD SCIENCES, 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA, SEPTEMBER 25, 2007

2008

[69] D'Addona D, Carotenuto A, Novellino E, Piccand V, Reubi JC, Di Cianni A, Gori F, Papini AM, Ginanneschi M. Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. J Med Chem 2008; 51(3):512-520. DOI: 10.1021/jm070886i

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, FEBRUARY 14, 2008

[70] F. Real Fernández, A. Chamois-Colson, J. Bayardon, F. Nuti, E. Peroni, R. Meunier-Prest, F. Lolli, M. Chelli, C. Darcel, S. Jugè, A.M. Papini. Ferrocenyl Glycopeptides as Electrochemical Probes to Detect Autoantibodies in Multiple Sclerosis Patients’ Sera. Biopolymers2008; 90(4):488-495. DOI: 10.1002/bip.20955

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, in 2008

[71] Cantel S, Isaad Ale C, Scrima M, Levy JJ, DiMarchi RD, Rovero P, Halperin JA, D'Ursi AM, Papini AM, Chorev M. Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition. J Org Chem 2008; 73(15), 5663-5674. DOI: 10.1021/jo800142s. FEATURED ARTICLE AND COVER.

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 1, 2008

[72] I. Paolini, F. Rizzolo, A.M. Papini. Optimized strategies for the synthesis of biomolecules by the microwave approach. Chimica Oggi-Chemistry Today 2008;26(4S), 35-38.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, JULY 2008

[73] A. Carotenuto, M.C. Alcaro, M.R. Saviello, E. Peroni, F. Nuti, A.M. Papini, E. Novellino, P. Rovero. Designed glycopeptides with different b-turn types as synthetic probes for the detection of autoantibodies, biomarkers of Multiple Sclerosis. J Med Chem 2008; 51(17), 5304-5309. DOI: 10.1021/jm800391y

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 20, 2008

[74] Le Chevalier Isaad A, Barbetti F, Rovero P, D’Ursi AM, Chelli M, Chorev M, Papini AM. N(alpha)-Fmoc-Protected omega-Azido and omega-Ynoic-alpha-Amino Acids as Building Blocks for the Synthesis of "Clickable" Peptides. Eur J Org Chem 2008; 31:5308-5314. DOI: 10.1002/ejoc.200800717

Published by WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, NOVEMBER 2008

[75] G. Sabatino, A.M. Papini. Advances in automatic, manual and microwave-assisted solid-phase peptide synthesis. REVIEW. Current Opinion in Drug Discovery & Development 2008; 11(6), 762-768.

Published by THOMSON REUTERS (SCIENTIFIC) LTD, 77 HATTON GARDEN, LONDON, EC1N 8JS, ENGLAND, 01 NOVEMBER 2008

2009

[76] S. Carganico, P. Rovero, J. A. Halperin, A.M. Papini, M. Chorev Building Blocks for the Synthesis of Post-Translationally Modified Glycated Peptides and Proteins. J Pept Sci 2009; 15(2), 67-71. DOI: 10.1002/psc.1105

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, FEBRUARY 2009

[77] M.C. Alcaro, I. Paolini, F. Lolli, P. Migliorini, P. Rovero, A.M. Papini. Peptide contribution to the diagnosis of autoimmune diseases. Chimica Oggi-Chemistry Today 2009; 27(2), 11-14.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2009

[78] M. Angeles Bonache, F. Nuti, A. Le Chevalier Isaad, F. Real-Fernandez, M. Chelli, P. Rovero, A.M. Papini. Synthesis of new ribosylated Asn building blocks as useful tools for glycopeptide and glycoprotein synthesis. Tetrahedron Lett 2009; 50(28), 4151-4153. DOI: 10.1016/j.tetlet.2009.04.124

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 15 JULY 2009

[79] A. Le Chevalier-Isaad, A.M. Papini, M. Chorev, P. Rovero. Side chain-to-side chain cyclization by click reaction. J Pept Sci 2009; 15(7), 451-454. DOI: 10.1002/psc.1141

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JULY 2009

[80] A.M. Papini. The use of post-translationally modified peptides for detection of biomarkers of immune-mediated diseases. REVIEW ZERVAS AWARD LECTURE. J Pept Sci 2009, 15(10), 621-628. DOI: 10.1002/psc.1166

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, OCTOBER 2009

2010

[81] Scrima M, Le Chevalier-Isaad A, Rovero P, Papini AM, Chorev M, D'Ursi AM. CuI-Catalyzed Azide–Alkyne Intramolecular i-to-(i+4) Side-Chain-to-Side-Chain Cyclization Promotes the Formation of Helix-Like Secondary Structures. Eur J Org Chem 2010; 3:446-457. DOI: 10.1002/ejoc.200901157

Published by WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, JANUARY 2010

[82] F. Real-Fernández, F. Nuti, M.A. Bonache, M. Boccalini, S. Chimichi, M. Chelli, A.M. Papini. Microwave-assisted reaction of glycosylamine with aspartic acid. Amino Acids 2010; 39(2), 599-604. DOI: 10.1007/s00726-010-0484-8

Published by SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA, JULY 2010

[83] M. Frediani, D. Sémeril, D. Matt, F. Rizzolo, A.M. Papini, P. Frediani, L. Rosi. Ring Opening Polymerization of rac-Lactide using a calix[4]arene-based Titanium (IV) Complex. Published by International Journal of Polymer Science 2010, 490724, 1-6.

HINDAWI PUBLISHING CORPORATION, 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA, in 2010

[84] M. Frediani, D. Sémeril, D. Matt, F. Rizzolo, A.M. Papini, P. Frediani, L. Rosi, M. Santella, G. Giachi. L-Lactide Polymerization by Calix[4]arene-Titanium (IV) Complex Using Conventional Heating and Microwave Irradiation. e-Polymers 2010; 19, 1-8.

Published by EUROPEAN POLYMER FEDERATION, 1, QUAI LEZAY-MARNESIA, F067000 STRASBOURG, FRANCE, FEBRUARY 24, 2010

[85] F. Nuti, E. Peroni, F. Real-Fernández, M.A. Bonache, A. Le Chevalier-Isaad, M. Chelli, N. Lubin-Germain, J. Uziel, P. Rovero, F. Lolli, A.M. Papini. Post-translationally modified peptides efficiently mimicking neo-antigens: a challenge for theragnostics of autoimmune diseases. Biopolymers 2010; 94(6), 791-799. DOI: 10.1002/bip.21456

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA in 2010

[86] Di Cianni A, Carotenuto A, Brancaccio D, Novellino E, Reubi JC, Beetschen K, Papini AM, Ginanneschi M. Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. J Med Chem 2010; 53(16):6188-6197. DOI: 10.1021/jm1005868

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 26, 2010

2011

[87] F. Gori, B. Mulinacci, L. Massai, C. Avolio, M. Caragnano, E. Peroni, S. Lori, M. Chelli, A.M. Papini, P. Rovero, F. Lolli. IgG and IgM antibodies to the refolded MOG(1-125) extracellular domain in humans. J Neuroimmunol 2011; 233(1-2), 216-220. DOI: 10.1016/j.jneuroim.2010.11.011

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, APRIL 2011

[88] F. Rizzolo, C. Testa, D. Lambardi, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and microwave-assisted SPPS approach: a comparative synthesis of PTHrP(1–34)NH₂. J Pept Sci 2011; 17(10), 708-714. DOI: 10.1002/psc.1395

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, OCTOBER 2011

[89] C. Selmi, A.M. Papini, P.Pugliese, M.C. Alcaro, M.E. Gershwin. Environmental pathways to autoimmune diseases: the cases of primary biliary cirrhosis and multiple sclerosis, Archives of Medical Science 2011; 7(3), 368-380. DOI: 10.5114/aoms.2011.23398

Published by TERMEDIA PUBLISHING HOUSE LTD, KLEEBERGA ST 2, POZNAN, 61-615, POLAND, JUNE 2011

2012

[90] C. Testa, F. Nuti, J. Hayek, C. De Felice, M. Chelli, P. Rovero, G. Latini, A.M. Papini. Di-(2-Ethylhexyl) Phthalate and Autism Spectrum Disorders. ASN NEURO (American Society for Neurochemistry) 2012; 4(4), 223-229. DOI:10.1042/AN20120015

Published by PORTLAND PRESS LTD, THIRD FLOOR, EAGLE HOUSE, 16 PROCTER STREET, LONDON WC1V 6 NX, ENGLAND in 2012

autism, di-(2-ethylhexyl) phthalate, endocrine disrupters, HPLC-ESI-MS urine analysis, secondary metabolites

[91] F. Real-Fernández, I. Passalacqua, E. Peroni, M. Chelli, F. Lolli, A.M. Papini, P. Rovero. Glycopeptide-based antibody detection in Multiple Sclerosis by surface plasmon resonance. Sensors2012; 12(5):5596-5607. DOI: 10.3390/s120505596

Published by MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, MAY 2012

[92] Scrima M, Grimaldi M, Di Marino S, Testa C, Rovero P, Papini AM, Chorev M, D'Ursi AM. Solvent independent conformational propensities of [1,2,3]triazolyl-bridged parathyroid hormone-related peptide-derived cyclo-nonapeptide analogues. Biopolymers 2012; 98(6):535-545. DOI: 10.1002/bip.22139

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA in 2012

[93] Guardiani C, Signorini GF, Livi R, Papini AM, Procacci P. Conformational landscape of N-glycosylated peptides detecting autoantibodies in multiple sclerosis, revealed by Hamiltonian replica exchange. J Phys Chem B 2012; 116(18):5458-5467. DOI: 10.1021/jp301442n

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, MAY 10, 2012

[94] Pandey S, Alcaro MC, Scrima M, Peroni E, Paolini I, Di Marino S, Barbetti F, Carotenuto A, Novellino E, Papini AM, D'Ursi AM, Rovero P. Designed glycopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J Med Chem 2012; 55(23):10437-10447. DOI: 10.1021/jm301031r

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, DECEMBER 13, 2012

2013

[95] Pandey S, Dioni I, Lambardi D, Real-Fernandez F, Peroni E, Pacini G, Lolli F, Seraglia R, Papini AM, Rovero P. Alpha actinin is specifically recognized by multiple sclerosis autoantibodies isolated using an N-glucosylated peptide epitope. Mol Cell Proteomics 2013; 12(2), 277-282. DOI: 10.1074/mcp.M112.017087

Published by AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA, FEBRUARY 2013

[96] Potenza M, Sabatino G, Giambi F, Rosi L, Papini AM, Dei L. Analysis of egg-based model wall paintings by use of an innovative combined dot-ELISA and UPLC-based approach. Analytical & Bioanalytical Chemistry 2013; 405(2-3), 691-701. DOI: 10.1007/s00216-012-6049-9

Published by SPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, JANUARY 2013

[97] Chanson J-B, Paolini I, Collongues N, Alcaro MC, Blanc F., Barbetti F., Fleury M., Peroni E, Rovero P, Rudolf G, Lolli F, Trifilieff E, Papini AM, de Seze J. Evaluation of new immunological targets in neuromyelitis optica. J Pept Sci 2013; 19(1):25-32. DOI: 10.1002/psc.2470

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JANUARY 2013

[98] Friligou I, Rizzolo F, Nuti F, Tselios T, Evangelidou M, Emmanouil M, Karamita M, Matsoukas J, Chelli M, Rovero P, Papini AM. Divergent and convergent synthesis of polymannosylated dibranched antigenic peptide of the immunodominant epitope MBP(83-99). Bioorg Med Chem 2013; 21(21):6718-6725. DOI: 10.1016/j.bmc.2013.08.008

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, NOVEMBER 1, 2013

[99] Candelaresi M, Ragnoni E, Cappelli C, Corozzi A, Lima M, Monti S, Mennucci B, Nuti F, Papini AM, Foggi P. Conformational analysis of Gly-Ala-NHMe in D(2)O and DMSO solutions: a two-dimensional infrared spectroscopy study. J Phys Chem B 2013; 117(46):14226-14237. DOI: 10.1021/jp406139t

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, NOVEMBER 21, 2013

2014

[100] Naegeli A, Neupert C, Fan YY, Lin CW, Poljak K, Papini AM, Schwarz F, Aebi M. Molecular analysis of an alternative N-glycosylation machinery by functional transfer from Actinobacillus pleuropneumoniae to Escherichia coli. J Biol Chem 2014; 289(4):2170-2179. DOI: 10.1074/jbc.M113.524462

Published by AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA, JANUARY 24, 2014

[101] Pratesi A, Gabbiani C, Michelucci E, Ginanneschi M, Papini AM, Rubbiani R, Ott I, Messori L. Insights on the mechanism of thioredoxin reductase inhibition by Gold N-heterocyclic carbene compounds using the synthetic linear Selenocysteine containing C-terminal peptide hTrxR(488-499): An ESI-MS investigation. J Inorg Biochem 2014; 136, 161-169. DOI: 10.1016/j.jinorgbio.2014.01.009

Published by ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, JULY 2014

[102] C. Gellini, G. Sabatino, A.M. Papini, M. Muniz-Miranda.SERS study of a tetrapeptide based on histidine and glycine residues, adsorbed on copper/silver colloidal nanoparticles. J Raman Spectrosc2014; 45(6), 418-423. DOI: 10.1002/jrs.4484

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JUNE 2014

[103] M. Di Pisa, P. Buccato, G. Sabatino, F. Real Fernández, B. Berti, F. Cocola, A.M. Papini, P. Rovero. Epitope Mapping of the N-terminal Portion of Tissue Transglutaminase Protein Antigen to Identify Linear Epitopes in Celiac Disease. J Pept Sci 2014; 20(9), 689-695. DOI: 10.1002/psc.2650

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2014

[104] Papini AM, Nuti F, Real-Fernandez F, Rossi G, Tiberi C, Sabatino G, Pandey S, Leoncini S, Signorini C, Pecorelli A, Guerranti R, Lavielle S, Ciccoli L, Rovero P, De Felice C, Hayek J. Immune dysfunction in Rett syndrome patients revealed by high levels of serum anti-N(Glc) IgM antibody fraction. J Immunol Res 2014:260973. DOI: 10.1155/2014/260973

Published by HINDAWI PUBLISHING CORP, 315 MADISON AVE 3RD FLR, STE 3070, NEW YORK, NY 10017 USA in 2014

[105] Auberger N, Di Pisa M, Larregola M, Chassaing G, Peroni E, Lavielle S, Papini AM, Lequin O, Mallet JM. Glaser oxidative coupling on peptides: stabilization of β-turn structure via a 1,3-butadiyne constraint. Bioorg Med Chem 2014; 22(24):6924-6932. DOI: 10.1016/j.bmc.2014.10.026

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, DECEMBER 15, 2014

[106] Testa C, Scrima M, Grimaldi M, D'Ursi AM, Dirain ML, Lubin-Germain N, Singh A, Haskell-Luevano C, Chorev M, Rovero P, Papini AM. 1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity. J Med Chem 2014; 57(22):9424-9434. DOI: 10.1021/jm501027w

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA in 2014.

2015

[107] Kolesinska B, Rozniakowski KK, Fraczyk J, Relich I, Papini AM, Kaminski ZJ. The Effect of Counter-ion and Tertiary Amine on the Efficiency of N-Triazinylammonium Sulfonates in Solution and Solid-Phase Peptide Synthesis. Eur J.O.C. 2015; 2:401-408. DOI: 10.1002/ejoc.201402862

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, JANUARY 2015

[108] Di Pisa M, Pascarella S, Scrima M, Sabatino G, Real-Fernández F, Chelli M, Renzi D, Calabrò A, D'Ursi AM, Papini AM, Rovero P. Synthetic peptides reproducing tissue transglutaminase-gliadin complex neo-epitopes as probes for antibody detection in celiac disease patients' sera. J Med Chem 2015; 58(3):1390-1399. DOI: 10.1021/jm5017126

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, FEBRUARY 12, 2015

[109] Smerieri A, Testa C, Lazzeroni P, Nuti F, Grossi E, Cesari S, Montanini L, Latini G, Bernasconi S, Papini AM, Street ME. Di-(2-ethylhexyl) phthalate metabolites in urine show age-related changes and associations with adiposity and parameters of insulin sensitivity in childhood. PLOS One 2015; 10(2):e0117831. DOI: 10.1371/journal.pone.0117831

Published by PUBLIC LIBRARY SCIENCE, 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA, FEBRUARY 23, 2015

[110] Pratesi A, Ginanneschi M, Melani F, Chinol M, Carollo A, Paganelli G, Lumini M, Bartoli M, Frediani M, Rosi L, Petrucci G, Messori L, Papini AM. Design and solid phase synthesis of new DOTA conjugated (+)-biotin dimers planned to develop molecular weight-tuned avidin oligomers. Org Biomol Chem 2015; 13(13):3988-4001. DOI: 10.1039/c4ob02685c

Published by ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND, 2015

[111] Rentier C, Monasson O, Nuti F, Rovero P, Sabatino G, Papini AM. Methionine sulfoxide- and sulfone-containing peptide synthesis: management of a relevant post-translational modifications in proteins. Chimica Oggi-Chemistry Today 2015; 33(2S):32-35.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2015

[112] Rentier C, Pacini G, Nuti F, Peroni E, Rovero P, Papini AM. Synthesis of diastereomerically pure Lys(Nå-lipoyl) building blocks and their use in Fmoc/tBu solid phase synthesis of lipoyl-containing peptides for diagnosis of primary biliary cirrhosis. J Pept Sci 2015; 21(5):408-414. DOI: 10.1002/psc.2761

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, MAY 2015

[113] Real-Fernández F, Rossi G, Lolli F, Papini AM, Rovero P. Label-free method for anti-glucopeptide antibody detection in Multiple Sclerosis. MethodsX 2015; 2:141-144. DOI: 10.1016/j.mex.2015.03.004

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2015

[114] Real Fernández F, Di Pisa M, Rossi G, Auberger N, Lequin O, Larregola M, Benchohra A, Mansuy C, Chassaing G, Lolli F, Hayek J, Lavielle S, Rovero P, Mallet JM, Papini AM. Antibody recognition in multiple sclerosis and Rett syndrome using a collection of linear and cyclic N-glucosylated antigenic probes. Biopolymers 2015; 104(5):560-576. DOI: 10.1002/bip.22677

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2015

[115] Papini AM, König E. Novel diagnostic tools and solutions for multiple sclerosis treatment: a patent review (2009-2014). REVIEW. Expert Opin Ther Pat 2015; 25(8):873-84. DOI: 10.1517/13543776.2015.1043267

Published by TAYLOR & FRANCIS LTD, 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND, AUGUST 2015

[116] Bellagha-Chenchah W, Sella C, Real Fernandez F, Peroni E, Lolli F, Amatore C, Thouin L, Papini AM. Interactions between Human Antibodies and Synthetic Conformational Peptide Epitopes: Innovative Approach for Electrochemical Detection of Biomarkers of Multiple Sclerosis at Platinum Electrodes. Electrochimica Acta 2015; 176, 1239-1247. DOI: 10.1016/j.electacta.2015.07.158

Published by PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 10 SEPTEMBER 2015

[117] Pacini G, Carotenuto A, Rentier C, Nuti F, Real-Fernandez F, Brancaccio D, Sabatino G, Larregola M, Peroni E, Migliorini P, Novellino E, Battezzati PM, Selmi C, Papini AM, Rovero P. Role of Lipoylation of the Immunodominant Epitope of Pyruvate Dehydrogenase Complex: Toward a Peptide-Based Diagnostic Assay for Primary Biliary Cirrhosis. J Med Chem 2015; 58(16):6619-6629. DOI: 10.1021/acs.jmedchem.5b00783

Published by AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, AUGUST 27, 2015

[118] Real-Fernández F, Cimaz R, Rossi G, Simonini G, Giani T, Pagnini I, Papini AM, Rovero P. Surface plasmon resonance-based methodology for anti-adalimumab antibody identification and kinetic characterization. Anal Bioanal Chem 2015; 407(24):7477-7485. DOI: 10.1007/s00216-015-8915-8

Published by SPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, SEPTEMBER 2015

[119] Becucci L, Benci S, Nuti F, Real-Fernandez F, Vaezi Z, Stella L, Venanzi M, Rovero P, Papini AM. Interaction Study of Phospholipid Membranes with an N-Glucosylated β-Turn Peptide Structure Detecting Autoantibodies Biomarkers of Multiple Sclerosis. Membranes 2015; 5(4):576-596. DOI: 10.3390/membranes5040576

Published by MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, DECEMBER 2015

2016

[120] Walvoort MT, Testa C, Eilam R, Aharoni R, Nuti F, Rossi G, Real-Fernandez F, Lanzillo R, Brescia Morra V, Lolli F, Rovero P, Imperiali B, Papini AM. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae. Sci Rep 2016; 6:39430. DOI: 10.1038/srep39430

Published by NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, DECEMBER 23, 2016

[121] Sabatino G, Guryanov I, Rombecchi A, Zanon J, Ricci A, Cabri W, Papini AM, Rovero P. Production of peptides as generic drugs: a patent landscape of octreotide. REVIEW. Expert Opin Ther Pat 2016; 26(4):485-495. DOI: 10.1517/13543776.2016.1158810

Published by TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND, APRIL 2, 2016

[122] De Felice C, Leoncini S, Signorini C, Cortelazzo A, Rovero P, Durand T, Ciccoli L, Papini AM, Hayek J. Rett syndrome: An autoimmune disease? REVIEW. Autoimmunity Reviews 2016; 15(4):411-416. DOI: 10.1016/j.autrev.2016.01.011

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, APRIL 2016

[123] Giangrande C, Auberger N, Rentier C, Papini AM, Mallet JM, Lavielle S, Vinh J. Multi-Stage Mass Spectrometry Analysis of Sugar-Conjugated β-Turn Structures to be Used as Probes in Autoimmune Diseases. J Am Soc Mass Spectrom 2016; 27(4):735-747. DOI: 10.1007/s13361-015-1321-9

Published by SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA, APRIL 2016

[124] Pacini G, Ieronymaki M, Nuti F, Sabatino G, Larregola M, Aharoni R, Papini AM, Rovero P. Epitope mapping of anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a mouse model of multiple sclerosis: microwave-assisted synthesis of the peptide antigens and ELISA screening. J Pept Sci 2016; 22(1):52-58. doi: 10.1002/psc.2839

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JANUARY 2016

[125] Pascarella S, Tiberi C, Sabatino G, Nuti F, Papini AM, Giovannelli L, Rovero P. Serpin A1 C-Terminal Peptides as Collagen Turnover Modulators. CHEMMEDCHEM 2016; 11(16):1850-1855. doi: 10.1002/cmdc.201500472

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, AUGUST 19, 2016

[126] E. Peroni, F. Real Fernández, C. Gheri, F. Nuti, A.-C. Mitaine-Offer, F. Lolli, M.-A. Lacaille-Dubois, A.M. Papini. Natural Triterpene Glycosides for Antibody Recognition. Planta Med Lett 2016; 3(01): e2-e7. DOI: 10.1055/s-0035-1568263

Published by GEORG THIEME VERLAG KG, RUDIGERSTR 14, D-70469 STUTTGART, GERMANY, 2016

2017

[127] Champy AS, Mitaine-Offer AC, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Structural analysis of oleanane-type saponins from the roots of Wisteria frutescens. Magn Reson Chem 2017; 55(6), 595-600. DOI: 10.1002/mrc.4550

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, JUNE 2017

[128] Pratesi A, Ginanneschi M, Lumini M, Papini AM, Novellino E, Brancaccio D, Carotenuto A. DOTA-Derivatives of Octreotide Dicarba-Analogs with High Affinity for Somatostatin sst2,5 Receptors. Front Chem 2017; 5:8. DOI: 10.3389/fchem.2017.00008

Published by FRONTIERS MEDIA SA, AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND, 23 FEBRUARY 2017

[129] Pratesi A, Stazzoni S, Lumini M, Sabatino G, Carotenuto A, Brancaccio D, Novellino E, Chinol M, Rovero P, Ginanneschi M, Papini AM. Synthesis of dicarba-cyclooctapeptide Somatostatin analogs by conventional and MW-assisted RCM: a study about the impact of the configuration at Cα of selected amino acids. Chemical Engineering & Processing 2017; 122, 365-372. DOI:  10.1016/j.cep.2017.02.005

Published by ELSEVIER SCIENCE SA, PO BOX 564, 1001 LAUSANNE, SWITZERLAND, DECEMBER 2017

[130] Ieronymaki M, Nuti F, Brancaccio D, Rossi G, Real-Fernández F, Cao Y, Monasson O, Larregola M, Peroni E, Uziel J, Sabatino G, Novellino E, Carotenuto A, Papini AM, Rovero P. Structure-Activity Relationship Studies, SPR Affinity Characterization, and Conformational Analysis of Peptides That Mimic the HNK-1 Carbohydrate Epitope. CHEMMEDCHEM 2017; 12(10):751-759. DOI: 10.1002/cmdc.201700042

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MAY 22, 2017

[131] Uber, D; Wyrzykowski, D; Tiberi, C; Sabatino, G; Zmudzinska, W; Chmurzynski, L; Papini, AM; Makowska, J. Conformation-dependent affinity of Cu(II) ions peptide complexes derived from the human Pin1 protein ITC and DSC study. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 2017; 127:2, 1431-1443. DOI: 10.1007/s10973-016-5387-9

Published by SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, FEBRUARY 2017

[132] Champy AS, Mitaine-Offer AC, Paululat T, Papini AM, Lacaille-Dubois MA. Triterpene Saponins from Wisteria floribunda "macrobotrys" and "rosea". NATURAL PRODUCT COMMUNICATIONS 2017; 12:10, 1573-1576. https://doi.org/10.1177/1934578x1701201036

Published by NATURAL PRODUCTS INC, 7963 ANDERSON PARK LN, WESTERVILLE, OH 43081 USA, OCTOBER 2017

2018

[133] Grage SL, Kara S, Bordessa A, Doan V, Rizzolo F, Putzu M, Kubař T, Papini AM, Chaume G, Brigaud T, Afonin S, Ulrich AS. Orthogonal ¹⁸F-labeling for solid-state NMR reveals the conformation and orientation of short peptaibols in membranes. Chem Eur J 2018; 24(17), 4328-4335. DOI: 10.1002/chem.201704307

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MARCH 20, 2018

[134] C. Testa, D. D’Addona, M. Scrima, A.M. Tedeschi, A.M. D’Ursi, C. Bernhard, F. Denat, C. Bello, P. Rovero, M. Chorev, A.M. Papini. Design, Synthesis and Conformational Studies of [DOTA]-Octreotide Analogues Containing [1,2,3]Triazolyl as a Disulfide Mimetic. PEPTIDE SCIENCE 2018; 110(5) e24071. DOI: 10.1002/pep2.24071

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2018

[135] Kukacka Z, Iurascu M, Lupu L, Rusche H, Murphy M, Altamore L, Borri F, Maeser S, Papini AM, Hennermann J, Przybylski M. Antibody Epitope of human α-Galactosidase A revealed by affinity-mass spectrometry: a basis for reversing immunoreactivity in enzyme replacement therapy of Fabry Disease. CHEMMEDCHEM 2018; 13(9); 909-915. DOI:10.1002/cmdc.201800094

Published by WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, MAY 8, 2018

[136] Becucci L, Aloisi G, Papini AM, Guidelli R. Channel-forming activity of nisin in two mercury-supported biomimetic membranes. JOURNAL OF ELECTROANALYTICAL CHEMISTRY 2018; 812; 186-193. DOI:10.1016/j.jelechem.2017.11.061.

Published by ELSEVIER SCIENCE SA, PO BOX 564, 1001 LAUSANNE, SWITZERLAND, MARCH 1, 2018

[137] Champy-Tixier AS, Mitaine-Offer AC, Real-Fernández F, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Oleanane-type glycosides from the roots of Weigela florida "rumba" and evaluation of their antibody recognition. Fitoterapia 2018; 128:198-203. DOI: 10.1016/j.fitote.2018.04.017

Published by ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, JULY 2018

[138] C. Testa, A.M. Papini, M. Chorev, P Rovero. Copper-catalyzed azide alkyne cycloaddition (CuAAC)-mediated macrocylization of peptides: impact on conformation and biological activity. REVIEW. Curr Topics Med Chem 2018; 18(7), 591-610. DOI: 10.2174/1568026618666180518095755

Published by BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, in 2018

[139] M.E. Street, S. Angelini, S. Bernasconi, E. Burgio, A. Cassio, C. Catellani, F. Cirillo, A. Deodati, E. Fabbrizi, V. Fanos, G. Gargano, E. Grossi, L. Iughetti, P. Lazzeroni, A. Mantovani, L. Migliore, P. Palanza, G. Panzica , A.M. Papini, S. Parmigiani, B. Predieri, C. Sartori, G. Tridenti, S. Amarri. Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting. REVIEW. Int J Mol Sci 2018; 19(6):1647. DOI:10.3390/ijms19061647

Published by MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, JUNE 2018

[140] Nuti F, Gallo A, Real-Fernandez F, Crulli M, Rentier C, Piarulli F, Peroni E, Rossi G, Traldi P, Rovero P, Lapolla A, Papini AM. Antibodies to post-translationally modified mitochondrial peptide PDC-E2(167-184) in type 1 diabetes. Arch Biochem Biophys 2018; 659:66-74. DOI: 10.1016/j.abb.2018.09.021

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, DECEMBER 1, 2018

[141] A.M. Papini. From morphine to endogenous opioid peptides, e.g., endorphins: the endless quest for the perfect painkiller. Substantia 2018; 2(2): 81-91. DOI: 10.13128/substantia-63

Published by University Press, Firenze, ITALY, SEPTEMBER 24, 2018.

PROTEIN LEVELS AND AUTOANTIBODIES AGAINST LL37 AND IFI16 NUCLEIC ACID SENSORS IN PSORIATIC ARTHRITIS

2019

[142] Real-Fernández F, Pregnolato F, Cimaz R, Papini AM, Borghi MO, Meroni PL, Rovero P. Detection of anti-adalimumab antibodies in a RA responsive cohort of patients using three different techniques. Analytical Biochemistry 2019; 566, 133-138. DOI: 10.1016/j.ab.2018.11.018

Published by ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, FEBRUARY 1, 2019

[143] A. Mazzoleni, J.-M. Mallet, P. Rovero, A.M. Papini. Glycoreplica peptides to investigate molecular mechanisms of immune-mediated physiological versus pathological conditions Arch Biochem Biophys 2019; 663, 44-53. DOI: 10.1016/j.abb.2018.12.030

Published by ELSEVIER SCIENCE INC, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, MARCH 15, 2019

[144] I. Guryanov, F. Real-Fernández, G. Sabatino, N. Prisco, E. Popova, V. Korzhikov-Vlakh, B. Biondi, A.M. Papini, E. Korzhikova-Vlakh, P. Rovero, T. Tennikova. Modeling interaction between gp120 HIV protein and CCR5 receptor. J Pept Sci 2019; 25(2):e3142. DOI: 10.1002/psc.3142

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 24 JANUARY 2019

[145] C. Bello, P. Rovero, A.M. Papini. Just a spoonful of sugar: short glycans affects protein properties and functions. J Pept Sci 2019; 25(5), e31-67. DOI: 10.1002/psc.3167

Published by WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, MAY 2019

[146] V. Iaconisi, G. Secci, G. Sabatino, G. Piccolo, L. Gasco, A.M. Papini, G. Parisi. Effect of mealworm (Tenebrio molitor L.) larvae meal on amino acid composition of gilthead sea bream (Sparus aurata L.) and rainbow trout (Oncorhynchus mykiss W.) fillets. Aquaculture 2019; 513, 734403. Doi: 10.1016/j.aquaculture.2019.734403

[147] F. Nuti, C. Gellini, M. Larregola, L. Squillantini, R. Chelli, P.R. Salvi, O. Lequin, G. Pietraperzia, A.M. Papini. A photochromic azobenzene peptidomimetic of a β-turn model peptide structure as a conformational switch. Frontiers in Chemistry. Section: Supramolecular Chemistry 2019; 7, Art. 180. DOI: 10.3389/fchem.2019.00180

Published by FRONTIERS MEDIA SA, AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND, MARCH 29, 2019

[148] De Santis, M; Isailovic, N.; Generali, E.; Ceribelli, A.; Altamore, L.; Real-Fernandez, F.; Papini, A.M.; Rovero, P.; Sabatino, G.; Selmi, C. Humoral response against LL-37 in psoriatic disease: comment on the article by Yuan et al. ARTHRITIS & RHEUMATOLOGY 2019; 71(11), 1964-1965. Published in 2019. http://dx.doi.org/10.1002/art.41010

[149] Nuti F, Gallo A, Real-Fernandez F, Rentier C, Rossi G, Piarulli F, Traldi P, Carganico S, Rovero P, Lapolla A, Papini AM. Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation. Folia Biol (Praha). 2019;65(4):195-202.

[150] Nguyen DH, Mitaine-Offer AC, Maroso S, Papini AM, Paululat T, Bellaye PS, Collin B, Chambin O, Lacaille-Dubois MA. Cytotoxic glycosides from the roots of Weigela x "Bristol Ruby". Fitoterapia. 2019 Sep;137:104242. doi: 10.1016/j.fitote.2019.104242. Epub 2019 Jun 13.

[151] Real-Fernández F; Pacini G; Nuti F; Conciarelli G; De Felice C; Hayek J; Rovero P; Papini AM. Is aberrant N-glucosylation relevant to recognise anti-MOG antibodies in Rett syndrome? Substantia 2019, 3(2), 19-25. https://doi.org/10.13128/Substantia-632

2020

[152] M. Kijewska, F. Nuti, M. Wierzbicka, M. Waliczek, P. Ledwon, A. Staskiewicz, F. Real-Fernandez, G. Sabatino, P. Rovero, P. Stefanowicz, Z. Szewczuk, A.M. Papini. An Optimised Di-Boronate-ChemMatrix Affinity Chromatography to Trap Deoxyfructosylated Peptides as Biomarkers of Glycation. Molecules 2020, 25, 755. doi:10.3390/molecules25030755

[153] A. D’Ercole, G. Sabatino, L. Pacini, E. Impresari, I. Capecchi, A.M. Papini, P. Rovero. On-resin microwave-assisted copper-catalysed azide-alkyne cycloaddition of H1-relaxin B single chain “stapled” analogues. Peptide Science 2020, p.e24159. DOI: 10.1002/pep2.24159. Accepted on Feb. 28, 2020. First published:23 March 2020.

[154] B. Petit, A.-C. Mitaine-Offer, F. Real-Fernández, A.M. Papini, C. Delaude, T. Miyamoto C. Tanaka, P. Rovero, M.-A. Lacaille-Dubois. Triterpene glycosides from Blighia welwitschii and evaluation of their antibody recognition capacity in multiple sclerosis. Phytochemistry 2020, 176, 112392. doi.org/10.1016/j.phytochem.2020.112392

[155] A. Mazzoleni, F. Real-Fernandez, M. Larregola, F. Nuti, O. Lequin, A.M. Papini, J.-M. Mallet, P. Rovero. Hyperglucosylated adhesin derived peptides as antigenic probes in multiple sclerosis: structure optimisation and immunological evaluation. J. Pept. Sci. 2020;26:e3281; 1-11. doi.org/10.1002/psc.3281

[156] Nuti, F.; Fernandez, F.R.; Sabatino, G.; Peroni, E.; Mulinacci, B.; Paolini, I.; Pisa, M.D.; Tiberi, C.; Lolli, F.; Petruzzo, M.; Lanzillo, R.; Morra, V.B.; Rovero, P.; Papini, A.M. A Multiple N-Glucosylated Peptide Epitope Efficiently Detecting Antibodies in Multiple Sclerosis. Brain Sci. 2020, 10(7), 453. doi:10.3390/brainsci10070453. This article belongs to the Special Issue Advances in Multiple Sclerosis Research—Series I

[157] F. Errante, P. Ledwoń, R. Latajka, P. Rovero, A.M. Papini. Cosmeceutical peptides in the framework of sustainable wellness economy. Front. Chem. 2020, 8:572923. Women in Science: Chemistry. doi:10.3389/fchem.2020.572923.

[158] S. Pandey, Z. Tuma, E. Peroni, O. Monasson, A.M. Papini, M. Chottova Dvorakova.Identification of NPB, NPW and their receptor in the rat heart. International Journal of Molecular Sciences 2020, 21(21), 7827. doi:10.3390/ijms21217827

[159] A. Marciniak, W. Witak, G. Sabatino, A.M. Papini, J. Brasuń. Detailed insight into interaction of bicyclic somatostatin analogue with Cu(II) ions. Int. J. Mol. Sci. 2020, 21, 8794, 1-13. doi:10.3390/ijms21228794

2021

[160] P. Ledwoń, F. Errante, A.M. Papini, P. Rovero, R. Latajka. Peptides as Active Ingredients: a Challenge for Cosmeceutical Industry. Chemistry & Biodiversity 2021, 18, e2000833. doi: 10.1002/cbdv.202000833

[161] F. Errante; M. Menicatti; M. Pallecchi; L. Giovannelli; A.M. Papini; P. Rovero, G. Bartolucci. Susceptibility of cosmeceutical peptides to proteases activity: development of dermal stability test by LC-MS/MS analysis. Journal of Pharmaceutical and Biomedical Analysis 2021, 194, 5, 113775. doi: 10.1016/j.jpba.2020.113775.

[162] F. Real-Fernández, A. Gallo, F. Nuti, L. Altamore, G. Giovanna Del Vescovo, P. Traldi, E. Ragazzi, P. Rovero, A. Lapolla, A.M. Papini. Cross-reactive peptide epitopes of Enterovirus Coxsackie B4 and human glutamic acid decarboxylase detecting antibodies in Latent Autoimmune Diabetes in Adults versus Type 1 Diabetes. Clinica Chimica Acta 2021, 515, 73-79. doi.org/10.1016/j.cca.2021.01.002. Available online January 7, 2021.

[163] Sabatino, G.; D'Ercole, A.; Pacini, L.; Zini, M.; Ribecai, A.; Paio, A.; Rovero, P.; Papini, A.M. An optimized scalable fully automated solid-phase microwave-assisted cGMP-ready process for the preparation of Eptifibatide. Org. Process Res. Dev. 2021, 25, 3, 552–563. doi.org/10.1021/acs.oprd.0c00490. Special issue Women in process chemistry.  

[164] Staśkiewicz A., Ledwoń P., Rovero P., Papini A.M., Latajka R. Triazole-Modified Peptidomimetics: An opportunity for Drug Discovery and Development Front. Chem. 9:674705. doi: 10.3389/fchem.2021.674705

[165] P. Ledwoń, A.M. Papini, P. Rovero, R. Latajka. Peptides and Peptidomimetics as Inhibitors of Enzymes Involved in Fibrillar Collagen Degradation. Materials 2021, 14(12), 3217. doi.org/10.3390/ma14123217

Other Publications (PhD Thesis, Notes and Editorials)

[1] A.M. Papini. Synthesis of peptides and investigation of their chimica, biopharmacological and immunological profile. PhD tesi in Chemical Sciences. (I International cycle and III National Cycle. Fellowship from the Italian Ministry of Education (Borsa Ministero della Pubblica Istruzione). National Library in Rome and Florence (1990) 1-118.

[2] A.M. Papini. Towards peptide-based diagnostics. Chimica Oggi-Chemistry Today 2009; 27(2):2.

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2009

[3] A.M. Papini. Cosmetics toward peptide-based cosmeceutics. CHIMICA OGGI-CHEMISTRY TODAY 2010, 28, 6, 3-4. NOTE

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, NOVEMBER-DECEMBER 2010

[4] A.M. Papini. Peptide chemistry revolution. Chimica Oggi-Chemistry Today 2012, 30(2), 22-23. NOTE

Published by TEKNOSCIENZE PUBL, VIALE BRIANZA 22, 20127 MILANO, ITALY, MARCH-APRIL 2012

[5] Papini AM, Lavielle S, Lubell WD. Co-editors and PIPS organizers. Peptides in Paris. EDITORIALE - SPECIAL ISSUE. Biopolymers 2015; 104(5):v-vii. DOI: 10.1002/bip.22738

IF: 1,99 - Citations: 0 (Scopus); 0 (WoS);

Published by WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, SEPTEMBER 2015

[6] A.M. Papini. Meet Our Regional Editor. Protein and Peptide Letters 2017, 24(3), 189. EDITORIAL

Published by Bentham Science Publishers, MARCH 2017.

[7] A.M. Papini, V. Schettino. L’intelligenza artificiale manderà l’esperimento in soffitta? December 9, 2020. Colombaria Oggi. Rivista online. http://www.colombaria.it/rivistaonline/archives/1410

Patents

(Period 2005-2021)

[1] Inventors: Papini A.M.,Rovero P., Chelli M., Lolli F. “Glycopeptides, their preparation and use in the diagnosis or therapeutic treatment of Multiple Sclerosis”. PCT (2003) WO 03000733 A2. Italian Patent n. 0001327122 (27/04/2005). Granted USA, Australian and European Patent (02/08/2005). Applicant: University of Florence, Italy. Licensed to IMMCO Diagnostics, Buffalo, USA.

[2] Inventors: Pinto F., Papini A.M., Chelli M., Rovero P., Lolli F. “Immuno-absorption columns for the subtraction of antibodies from blood with selective plasma filtration techniques”. PCT International Application (2003) WO 2003009887 Priority Application: IT 2001-FI144.Applicant: University of Florence, Italy.

[3] Inventors: Kaminski Z.J., Papini A.M., Kolesinska B., Kolesinska J., Jastrzabek K., Sabatino G., Bianchini R. “Process for the preparation of N-triazinylammonium salts”. Filing date 07/11/2005. PCT/EP2005/055793 (2005). Applicant: Italvelluti S.p.a. Kaminski Z.J., Papini A.M., Jastrzabek K., Kolesinska B., Kolesinska J., Sabatino G., Bianchini R. “Process for the preparation of n-triazinylammonium salts”. PCT Int. Appl. (2007), 14pp. CODEN: PIXXD2 WO 2007051496 A1 20070510 AN 2007:511982 CAPLUS. Licensed to ITALVELLUTI (Italy).

[4]Inventors: Giuntini M., Ginanneschi M., Chelli M., Papini A.M. “Somatostatin analogues” Filing date 10.03.2005. EPC Application (2005) 05101866.1-2401 Priority Application: IT/10.03.04/ITA FI20040057. Applicant: Giuntini M. Inventors: Giuntini M., Ginanneschi M., Chelli M., Papini A.M. “Preparation of somatostatin analogues”. Appl. (2005), CODEN: EPXXDW EP 1598366 A1 20051123 CAN 144:7091 AN 2005:1235907 CAPLUS

[5] Inventors: Alcaro M.C., Chelli M., Lolli F., Migliorini P., Paolini I., Papini A.M., Rovero P. “Galactosylated peptides, their preparation and use in autoimmune diseases diagnosis”. European patent EP2050761 B1. Applicant: Toscana Biomarkers Srl.

[6] Inventors: Pratesi F., Alcaro M.C., Chelli M., Fantini P., Lolli F., Paolini I., Papini A.M., Rovero P., Migliorini P. “Detection of anti-ribosomal P protein antibodies by means of synthetic peptides”. EP09167004.2 (2009). Patent application number EP10168270.6 - PCT/EP2011/061006 (2010). European patent application EP 2284188 A1 - US 2011028409 A1. Applicant: Toscana Biomarkers Srl. Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[7]Inventors: Alcaro M.C., Pratesi F., Paolini I., Chelli M., Lolli F., Papini A.M., Rovero P., Migliorini P. “Method for the diagnosis of rheumatoid arthritis”. Patent application number EP11167420.6. (2011). Applicant: Toscana Biomarkers Srl. Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India).

[8] Inventors: Pratesi F., Alcaro M.C., Chelli M., Lolli F., Paolini I., Papini A.M., Rovero P., Migliorini P. “Histone citrullinated peptides and uses thereof”. European patent application EP2402368 A1 - WO2012001103 A1. Applicant: Toscana Biomarkers Srl. Non exclusive licenses to Theradiag (France), DIESSE (Italy), DIAMETRA (Italy), Amar Immunodiagnostics (India). MoD&LS produces the peptide antigens for DIAMETRA

[9] Inventors: Denat F., D’Addona D., Bernhard C., Papini-Rovero A.M., Chorev M.. “Clicked somatostatin conjugated analogs for biological applications”. EP 11193530, 14.12.2011. Applicants: Université de Cergy-Pontoise CNRS and Université de Bourgogne.

[10] Inventors: Hayek J., De Felice C., Papini A.M., Rovero P., Nuti F., Real-Fernandez F., Sabatino G., Tiberi C. “Nuovi peptidi glicosilati”. Italian patent application FI2012000107 (25/05/2011). Applicant: Azienda Ospedaliera Universitaria Senese. Licensed to Toscana Biomarkers (Italy).

[11] Inventors: Errante F., Giovannelli L., Papini A.M., Rovero P. Nuovo principio attivo cosmeceutico. “Bioactive peptides and compositions comprising them”. International PCT application n. IB2020/055291. Priority 07/06/2019. Applicants: Espikem Srl (80%), Università di Firenze (20%).

 Peer-reviewed articles published in books (Period 1983-2021)

1993-2000

[1] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi. Cyclization of histidine azide: A side reaction during peptide synthesis. In: Peptides 1992. Proceedings of the 22nd European Peptide Symposium. C.H. Schneider and A.N. Eberle (Eds.). Pubblicato da Escom Science Publishers B.V. a Leiden, The Netherlands in 1993. pp. 255-256. ISBN 90-72199-16-2. Chem. Abs., 1994, 121, 281171

[2] L. Quartara, G. Balacco, C.A. Maggi, P. Rovero, M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi. Conformation-activity relationship on MEN 10376 neurokinin A antagonist: Effect of cyclization. In: Peptides 1992. Proceedings of the 22nd European Peptide Symposium. C.H. Schneider and A.N. Eberle (Eds.). Pubblicato da Escom Science Publishers B.V. a Leiden, The Netherlands in 1993, pp. 591-592. ISBN 90-72199-16-2. Chem. Abs., 1994, 121, 222201.

[3] L. Moroder, K. Köcher, A.M. Papini, M. Dufresne, C.H. Schneider. The mode of Peptide-Antigen Presentation Critically Affects The Specificity of Both Immune Response and Antigen-Antibody Recognition. In: Chemistry of Peptides and Proteins. D. Brandenburg, V. Ivanov and W. Voelter (Eds.). Pubblicato da Verlag Mainz a Aachen, Germany in 1993, Vol. 5/6, part B, pp. 783-791. ISBN 3-925714-84-7. Chem. Abs., 1994, 121, 298655.

[4] D. Pinzani, A.M. Papini, M.E. Vallecchi, M. Chelli, M. Ginanneschi, C.A. Maggi, R. Patacchini, M. Astolfi, L. Quartara, F.M. Arcamone, G. Rapi. Synthesis and biological activities of glycopeptides of NK2 receptor antagonists. In: Peptides: Chemistry, Structure and Biology. Proceedings of the 13^th American Peptide Symposium. P.T.P. Kaumaya and R.S. Hodges (Eds.). Pubblicato da da Springer Netherlands a Dordrecht, The Netherlands in 1996, Vol. 4, pp. 649-650. ISBN 978-90-72199-19-5. Chem. Abs., 1996, 126, 26939.

[5] A.M. Papini, S. Mazzucco, R. Fioresi, E. Nardi, M. Ginanneschi, M. Chelli, S. Matà, F. Lolli, F. Pinto, B. Mazzanti, L. Massacesi, M. Vergelli. [Asn³¹(N-b-d-Glucopyranosyl)]hMOG(30-50): an antigen to identify anti-hMOG peptide antibodies in multiple sclerosis patients. In: Proceedings of the 10^th International Congress of Immunology, New Delhi, India, 1-6 November 1998. Pubblicato da Monduzzi Editore, International Proceedings Division Bologna, Italy, Ottobre 1998, pp. 1239-1244. ISBN 88-323-1101-1.

[6] A.M. Papini, S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi and G. Rapi. Fmoc-2-aminopalmitic acid for the synthesis of lipopeptides with an hydrophobic chain on a C-C bond. In: Peptides: Frontiers of Peptide Science. Proceedings of the 15^th American Peptide Symposium. James P. Tam andPravin T.P. Kaumaya (Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 1999, Vol. 5, pp. 345-346. DOI: 10.1007/0-306-46862-X. ISBN 978-0-7923-5160-3 (Hardcover). Chem. Abs., 1999, 131, 200040.

[7] A.M. Papini, S. Mazzucco, D. Pinzani, M. Biondi, M. Chelli, M. Ginanneschi, G. Rapi, B. Mazzanti, M. Vergelli, L. Massacesi, L. Amaducci. Lipoderivatives of an immunodominant epitope of myelin basic protein increased T cell responsiveness in Lewis rats. In: Peptides: Frontiers of Peptide Science. Proceedings of the 15^th American Peptide Symposium. James P. Tam andPravin T.P. Kaumaya (Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 1999,. Vol. 5, pp. 700-702. DOI: 10.1007/0-306-46862-X. ISBN 978-0-7923-5160-3 (Hardcover). Chem. Abs., 1999, 131, 227631.

[8] S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, E. Traggiai, M. Vergelli, B. Mazzanti, G. Rapi, L. Massacesi, A.M. Papini. Comparison of the T Cell Proliferative Response to Lipopeptides of the Immunodominant EpitopeshMBP(83-99) and hMBP(141-160). In: Peptides 1998. Proceedings of the 25thEuropean Peptide Symposium. S. Bajusz and F. Hudecz (Eds.). Pubblicato da Akadémiai Kiadò a Budapest (Hungary) in 1999, pp. 604-605. ISBN 963-0-576-228. Chem. Abs., 2000, 134, 41080

[9] S. Mazzucco, R. Fioresi, S. Matà, M. Vergelli, M. Chelli, F. Lolli, M. Ginanneschi, F. Pinto, B. Mazzanti, L. Massacesi, G. Rapi, A.M. Papini. Glycopeptides of hMOG(30-50) Detect Antibody Response in Multiple Sclerosis and other Neurological Diseases. In: Peptides 1998. Proceedings of the 25thEuropean Peptide Symposium. S. Bajusz and F. Hudecz (Eds.). Pubblicato da Akadémiai Kiadò a Budapest in 1999, pp. 46-47. ISBN 9630576228. Chem. Abs., 2000, 133, 361706

[10]A.M. Papini, E. Nardi, S. Mazzucco, B. Mazzanti, E. Traggiai, C. Ballerini, H. Kalbacher, H. Beck, M. Chelli, M. Ginanneschi, L. Massacesi and M. Vergelli. Lipophilic modifications of peptide epitopes: T-cell response and susceptibility to peptidases.In: Peptides for the New Millenium. Proceedings of the 16th American Peptide Symposium. G.B. Fields, J.P. Tam and G. Barany (Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2002, Vol. 6, pp.697-699. DOI: 10.1007/0-306-46881-6. ISBN 978-0-306-46881-0 (eBook), ISBN 978-0-7923-6445-0 (Hardcover). Chem. Abs., 2001, 135, 59864.

[11] E. Nardi,S. Mazzucco, S. Matà, M. Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli, A.M. Papini. Recombinant MOG from baculovirus inhibits anti-hMOG(30-50) antibodies by the synthetic antigen [Asn³¹(Glc)]hMOG(30-50). In: Peptides for the New Millenium. Proceedings of the 16th American Peptide Symposium. G.B. Fields, J.P. Tam and G. Barany (Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2002, Vol. 6, pp. 708-709. DOI: 10.1007/0-306-46881-6. ISBN 978-0-306-46881-0 (eBook), ISBN 978-0-7923-6445-0 (Hardcover). Chem. Abs., 2001, 135, 60022.

2001

[12] E. Nardi, M. Chelli, M. Ginanneschi, S. Meini, L. Quartara, M.R. Altamura, C.A. Maggi, F. Formaggio, C. Toniolo, Q.B. Broxterman, P. Rovero, A.M. Papini. Lipophilic modifications of bradykinin agonists, In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp. 929-930. ISBN 2-84254-048-4. Chem. Abs., 2003, 140, 175310.

[13] J. Uziel, M.C. Alcaro, G. Sabatino, A. Di Fenza, M. Ginanneschi, M. Chelli, P. Rovero, A.M. Papini.Constrained head-to-tail cyclopeptides by amino acid side chain anchoring to trityl resins. In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp. 285-286. ISBN 2-84254-048-4. Chem. Abs., 2003, 140, 199689

[14] E. Nardi, E. Mastrangelo,S. Matà, B. Mazzanti, V. Zipoli,M. Chelli, M. Ginanneschi, L. Massacesi, M. Vergelli,F. Lolli, F. Pinto,A.M. Papini.Study of the role of the glycosyl moiety in autoantibody recognition in Multiple Sclerosis. In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp. 895-896. ISBN 2-84254-048-4. Chem. Abs., 2003, 139, 83847.

[15] Carotenuto, A.M. D’Ursi, E. Nardi, E. Mastrangelo, A.M. Papini,P. Rovero. Conformational studies on a glycopeptide of the human Myelin Oligodendrocyte Glycoprotein. In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp. 469-470. ISBN 2-84254-048-4. Chem. Abs., 2003, 140, 212640.

[16] A.M. Papini,E. Nardi, B. Mazzanti, T. Biagioli, E. Traggiai,M. Chelli, M. Ginanneschi, H. Kalbacher, L. Massacesi, Marco Vergelli. Effect of lipoconjugation on MBP peptide epitopes for CD4+ T cell responsiveness. In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp. 69-70. ISBN 2-84254-048-4. Chem. Abs., 2003, 140, 161980.

[17] E. Peroni, G. Caminati, P. Baglioni, M. Chelli, A.M. Papini.A new lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models. In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp. 989-990. ISBN 2-84254-048-4. Chem. Abs., 2003, 140, 141967.

[18] M.C. Alcaro, A.M. Papini, M. Chelli, D.Fishlock, C. Atkins, and G.A. Lajoie. Stereoselective syntheses of b,g-unsaturated amino acids. In: Peptides 2000. Proceedings of the 26th European Peptide Symposium. J. Martinez ; J.-A. Fehrentz (Eds.). Pubblicato da Editions EDK, Paris, France in 2001, pp.359-360. ISBN 2-84254-048-4. Chem. Abs., 2003, 140, 164146.

2002

[19] A. Carotenuto, A. Di Fenza, E. Nardi, A.M. Papini, P. Rovero. Conformational studies of a glycopeptide recognized with high affinity by autoantibodies in Multiple Sclerosis. In: Peptides. The Wave of the Future. Proceedings of the Second International and the Seventeenth American Peptide Symposium. R.A. Houghten and M. Lebl (Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2001, Vol. 7, pp. 340-341. DOI: 10.1007/978-94-010-0464-0. ISBN 978-94-010-0464-0 (eBook), ISBN 978-94-010-3905-5 (Softcover). Chem. Abs., 2002, 138, 380990.

[20] M.C. Alcaro, G. Sabatino, M. Ginanneschi, M. Chelli, A. Di Fenza, P. Rovero, A.M. Papini.A synthetic strategy toward constrained head-to-tail cyclopeptides. In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italyin 2002, pp. 16-17. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 28295.

[21] M.C. Alcaro, T. Terzani, F. Nuti, M. Chelli, F. Machetti, L. Quartara, R. Patacchini, S. Meini, S. Giuliani, A. Brandi, P. Rovero, A.M. Papini. New constrained amino acids for the study of the role of the basic residues in bradykinin antagonists. In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italyin 2002, pp. 18-19. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 28296.

[22] F. Nuti, S. Cicchi, E. Peroni, M. de la Cruz Pozo-Carrero, B. Mazzanti, M. Pazzagli, F. Lolli,M. Chelli, A.M. Papini, A. Brandi. Synthesis of new Fmoc-protected iminosugars to study the role of the glycosyl moiety in autoantibody recognition in autoimmune diseases. In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italy in 2002, pp. 238-239. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 52673.

[23] G. Sabatino, B. Mulinacci, M.C. Alcaro, M. Chelli, P. Rovero, A.M. Papini. A comparative study of coupling reagents for automatic multiple peptide synthesizers. In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italy in 2002, pp. 272-273. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 28422.

[24] B. Mulinacci, E. Peroni, G. Sabatino, B. Mazzanti, M. Pazzagli, M. de la Cruz Pozo-Carrero, M. Chelli, A. Carotenuto, P. Rovero, F. Lolli, A.M. Papini. Towards rationally designed glycopeptide antigens recognizing autoantibodies in Multiple Sclerosis patients. In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italy in 2002, pp. 388-389. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 37314.

[25] E. Peroni, F. Lolli, B. Mulinacci, F. Nuti, M. Chelli, P. Rovero, A.M. Papini. Innovative biocompatible immunoadsorbents containing immobilized selective glycopeptide antigens for Multiple Sclerosis therapy, In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italy in 2002, pp. 584-585. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 37453.

[26]A.M. Papini,B. Mulinacci, E. Peroni, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, S. Matà, F. Lolli, CSF114(Glc): the glycopeptide detecting autoantibodies in Multiple Sclerosis. PepKit, the first diagnostic test to follow-up the disease activity. In: Peptides 2002. Proceedings of the 27th European Peptide Symposium. E. Benedetti; C. Pedone (Eds.). Pubblicato da Edizioni Ziino, Castellammare di Stabia, Italy in 2002, pp. 998-999. ISBN 88-900948-1-8. Chem. Abs., 2004, 141, 52674.

2004

[27] M.C. Alcaro, P. Campiglia, P. Grieco, E. Novellino, M. Chelli, A.M. Papini. An efficient microwave-assisted synthesis of 2,5-diketopiperazines libraries. In: Peptide Revolution. Genomics, Proteomics & Therapeutics. The Proceedings of the 18th American Peptide Symposium.M. Chorev & T.K. Sawyer(Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2004, Vol. 8,pp. 17-18. ISBN 978-1-4020-2816-8 (Hardcover).

[28] G. Sabatino, M.C. Alcaro, M.C. Pozo-Carrero, M. Chelli, P. Rovero, A.M. Papini.Assessment of 6Cl-HOBt-based coupling reagents in solid-phase cyclopeptide synthesis. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. The Proceedings of the 18th American Peptide Symposium.M. Chorev & T.K. Sawyer(Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2004, Vol. 8,pp. 49-50. ISBN 978-1-4020-2816-8 (Hardcover).

[29] E. Peroni, F. Lolli, B. Mazzanti, M. Pazzagli, B. Bonetti, J. Hoebeke, M. Chelli, P. Rovero, A.M. Papini.Isolation and characterization of autoantibodies in Multiple Sclerosis patients sera: towards a novel apheresis treatment. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. The Proceedings of the 18th American Peptide Symposium.M. Chorev & T.K. Sawyer(Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2004, Vol. 8, pp. 75-76. ISBN 978-1-4020-2816-8 (Hardcover).

[30] F. Nuti, I. Paolini, B. Mulinacci, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, F. Lolli, M. Chelli, F.M. Cordero, A. Brandi, A.M. Papini. Small focused library of CSF114-type glycopeptides for the characterization of autoantibody recognition in Multiple Sclerosis, In: Peptide Revolution: Genomics, Proteomics & Therapeutics. The Proceedings of the 18th American Peptide Symposium.M. Chorev & T.K. Sawyer(Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2004, Vol. 8,pp. 77-78. ISBN 978-1-4020-2816-8 (Hardcover).

[31] A.M. Papini, B. Mulinacci, A. Carotenuto, B. Bonetti, G. Sabatino, E. Peroni, F. Nuti, M.C. Alcaro, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, L. Massacesi, L. Battistini, M. Chelli, P. Rovero, F. Lolli. MS PepKit: the first diagnostic test to follow-up Multiple Sclerosis. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. The Proceedings of the 18th American Peptide Symposium.M. Chorev & T.K. Sawyer(Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2004, Vol. 8,pp.942-944. ISBN 978-1-4020-2816-8 (Hardcover).

[32] B. Mulinacci, F. Nuti, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, B. Mazzanti, M. Pazzagli, F. Lolli, A.M. Papini. Structure-activity relationship study of glycopeptide antigens recognizing specific autoantibodies in Multiple Sclerosis. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. The Proceedings of the 18th American Peptide Symposium.M. Chorev & T.K. Sawyer(Eds.). Pubblicato da Springer Netherlands a Dordrecht, The Netherlands in 2004, Vol. 8,pp. 1007-1008. ISBN 978-1-4020-2816-8 (Hardcover).

2005

[33] D. D’Addona, M. Chelli, A.M. Papini, A. Carotenuto, F. Budelli, M. Ginanneschi.Synthesis of a new dicarba-analogue of the drug octreotide^â. In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 202-203. ISBN 965-90833-0-0.

[34]B. Kolesinska, G. Sabatino, J. Kolesinska, M. Chelli, P. Rovero, Z. Kaminski, and A.M. Papini. ACP solid phase synthesis by new efficient TBCRs.In: Peptides 2004. Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 232-233. ISBN 965-90833-0-0.

[35] A.M. Papini, B. Kolesinska, G. Sabatino, J. Kolesinska, and Z. Kaminski. Triazine-based coupling reagents useful tools for SPPS. In: Peptides 2004. Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 252-253. ISBN 965-90833-0-0.

[36]M. de la Cruz Pozo-Carrero, B. Kolesinska, G. Sabatino, M. Chelli, P. Rovero, Z. Kaminski, and A.M. Papini. An efficient strategy for attachment of Fmoc-amino acids to resins by TBCRs. In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 257-258. ISBN 965-90833-0-0.

[37] G. Sabatino, B. Kolesinska, M. Chelli, P. Rovero, Z. Kaminski, A.M. Papini. Automatic SPPS by the new generation of TBCRs. In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 263-264. ISBN 965-90833-0-0.

[38] K. Jastrzabek, B. Kolesinska, M. Blaszczyk, M.L. Glòwka, A.M. Papini, Z. Kaminski. 2-Chloro-4,6-dibenzyloxy-1,3,5-triazine and N-(4,6-dibenzyloxy-1,3,5-triazinyl-2)ammonium tetrafluoroborates as highly efficient coupling reagents for peptide synthesis in solution.In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 335-336. ISBN 965-90833-0-0.

[39] J. Kolesinska, B. Kolesinska, A.M. Papini, Z. Kaminski. Tetrafluoroborates of N-triazinylammonium salts as highly efficient coupling reagents for peptide synthesis in solution.In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 337-338. ISBN 965-90833-0-0.

[40] M.C. Alcaro, E. Naldini, B. Mulinacci, B. Mazzanti, M. Pazzagli, E. Peroni, M. Chelli, P. Rovero, A.M. Papini. Identification of new autoantigens in Multiple Sclerosis by glycopeptide libraries. In: Peptides 2004. Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 374-375. ISBN 965-90833-0-0.

[41] B. Mulinacci, I. Paolini, A. Carotenuto, B. Mazzanti, M. Pazzagli, M. Chelli, F. Lolli, P. Rovero, A.M. Papini. b-Hairpin glycopeptides as mimetic autoantigens in multiple sclerosis. In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005), pp. 593-594. ISBN 965-90833-0-0.

[42] I. Paolini, F. Nuti, B. Kolesinska, F. Cardona, M. Chelli, A. Brandi, A.M. Papini. New glycosylated building-blocks useful for glycopeptide synthesis. In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in 2005, pp. 597-598. ISBN 965-90833-0-0.

[43] E. Peroni, F. Peri, F. Nuti, M. Chelli, A.M. Papini. Synthetic strategies for forming the glycan-peptide linkage. In: Peptides 2004: Bridges Between Disciplines. Proceedings of the 28th European Peptide Symposium. M. Flegel, M. Fridkin, C. Gilon, J. Slaninova (Eds.). Pubblicato da Kenes International, Geneva, Switzerland, in Israel, in2005, pp. 599-600. ISBN 965-90833-0-0.

2006

[44]I. Paolini, F. Nuti, G. Sabatino, M. Chelli, A.M. Papini. Microwave-assisted synthesis of N-glycosylated building blocks. In: Understanding Biology Using Peptides: Proceedings of the Nineteenth American Peptide Symposium. S.E. Blondelle (Ed.). Pubblicato da Springer 2006 edition, in 2006, Series: American Peptide Symposia (Book 9), pp. 190-191. ISBN-10: 0387265694, ISBN-13: 978-0387265698.

[45]B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, A.M. Papini. Cross-reactivity studies of rMOGED with synthetic putative autoantigens CSF114(Glc) and [N³¹(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. In: Understanding Biology Using Peptides. S.E. Blondelle (Ed.). Pubblicato da Springer New York, USA, on October 23, 2007, Vol. 9, Part 11, pp. 769-770. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

[46]F. Nuti, I. Paolini, E. Peroni, F. Real-Fernandez, M. Pazzagli, M.C. Pozo-Carrero, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. Does an Aberrant Glucosylation Trigger Autoimmunity in Multiple Sclerosis? In: Understanding Biology Using Peptides. S.E. Blondelle (Ed.). Pubblicato da Springer New York, USA, on October 23, 2007, Vol. 9, Part 11, pp. 775-776. (2006). ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

[47]M.C. Alcaro, F. Barbetti, F. Nuti, F. Real-Fernandez, B. Mazzanti, M. Chelli, P. Rovero, A.M. Papini. Optimization of Multiple Sclerosis Antigenic Probes by a Combinatorial Approach. In: Understanding Biology Using Peptides. S.E. Blondelle (Ed.) Pubblicato da Springer New York, USA, on October 23, 2007, Vol. 9, Part 11, pp. 779-780. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

[48] E.S. Bulukin, E. Peroni, M. Minunni, M. Pazzagli, P. Rovero, M. Mascini, A.M. Papini. Development of an Efficient Multiple Sclerosis Diagnostic Technology Based on an Optical Glycopeptide Immunosensor. In: Understanding Biology Using Peptides. S.E. Blondelle (Ed.) Pubblicato da Springer New York, USA, on October 23, 2007, Vol. 9, Part 11, pp. 785-786. ISBN 978-0-387-26569-8 (Print) 978-0-387-26575-9 (Online).

2007

[49] B. Kolesińska, J. Kolesińska, A. Frymarkiewicz, K.K. Wąsikowska, N. Piątkowska, K.G. Jastrząbek, G. Sabatino, F. Rizzolo, A.M. Papini, Z.J. Kamiński. Synthesis of building blocks for peptide synthesis by using 4-(4,6-dimethoxy-[1,3,5]triazin-2-yl)-4-methyl-morpholinium toluene-4-sulfonate. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerlandin 2007, pp 518-519. ISBN 978-965-555-297-3.

[50] D. D'Addona, F. Gori, A. Di Cianni, F. Bucelli, M. Chelli, A.M. Papini, A. Carotenuto, M. Ginanneschi. A new synthetic approach to unsaturated and saturated dicarba-analogues of octreotide. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerlandin 2007, pp 582-583. ISBN 978-965-555-297-3.

[51] F. Nuti, E. Peroni, E.S. Bulukin, M. Minunni, B. Mulinacci, M. Chelli, M. Mascini, P. Rovero, A.M. Papini. Improvement of autoantibody detection in autoimmune diseases by innovative solid-phase glycopeptide based technologies. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland(2007), pp 588-589. ISBN 978-965-555-297-3.

[52] B. Kolesińska, J. Kolesińska, A. Frymarkiewicz, K.K. Rożniakowski, G. Sabatino, F. Rizzolo, A.M. Papini, Z.J. Kamiński. Sulfonates of N-triazinylammonium salts as highly efficient, inexpensive and environmentally friendly coupling reagents for peptide synthesis in solution. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland in 2007, pp 604-605. ISBN 978-965-555-297-3.

[53] B. Kolesińska, S. Grabowski, I. Konieczna, W. Kaca, E. Peroni, A.M. Papini, P. Rovero Z.J. Kamiński. Immunoenzymatic assay with peptide antigens immobilized on cellulose: effect of the linker on antibody recognition. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland in 2007, pp 616-617. ISBN 978-965-555-297-3.

[54] I. Paolini, F. Nuti, E. Peroni, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. An universal peptide scaffold to develop antigenic probes specific for autoimmune diseases. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium.  K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland in 2007, pp 672-673. ISBN 978-965-555-297-3.

[55] A. Le Chevalier, N. Lubin-Germain, J. Uziel, M. Chelli, F. Lolli, P. Rovero, A.M. Papini. Sugar building-blocks for solid-phase glycopeptides synthesis. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland in 2007, pp 680-681. ISBN 978-965-555-297-3.

[56] M.C. Alcaro, A. Carotenuto, C. Bonaccini, B. Mulinacci, G. Bonechi, F. Lolli, M. Chelli, P. Gratteri, A. Tramontano, E. Novellino, A.M. Papini, P. Rovero. Conformationally driven rational design of glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland in 2007, pp 684-685. ISBN 978-965-555-297-3.

[57] N. Alexandris, M.C. Alcaro, R. Bianchini, A.M. Papini. Design and Synthesis of heme peptides for bioremediation. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerland in 2007, pp 688-689. ISBN 978-965-555-297-3.

[58] F. Rizzolo, G. Sabatino, I. Paolini, M.C. Alcaro, M.R Moncelli, R. Guidelli, M. Chelli, A.M. Papini, P. Rovero. An efficient microwave-assisted solid phase synthesis of gramicidin a for studies in bilayer-lipid membrane. In: Peptides 2006. Proceedings of the 29th European Peptide Symposium. K. Rolka, P. Rekowski, J. Silberring (Eds.). Pubblicato da Kenes International, Geneva, Switzerlandin 2007, pp 690-691. ISBN 978-965-555-297-3.

2008

[59] F. Rizzolo, G. Sabatino, M. Fridkin, M. Chelli, P. Rovero, A.M. Papini. Microwave-assisted solid-phase peptide synthesis: shifting off the limitations affecting conventional synthetic strategies. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 156-157. ISBN 978-952-92-5198-8.

[60] M.A. Bonache, F. Nuti, A. Le Chevalier Isaad, E. Peroni, M. Chelli, P. Rovero, A.M. Papini. New Building Blocks Useful For The Synthesis Of Ribosylated Peptides. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 188-189. ISBN 978-952-92-5198-8.

[61] A. Le Chevalier Isaad, M. Scrima, S. Cantel, J. Levy, P. Rovero, A.M. D'Ursi, M. Chorev, A.M. Papini. Synthesis of a Series of Cyclic i-to-i+4 Side Chain-to-Side Chain 1,4-Disubstituted [1,2,3]triazolyl-Bridged PTHrP(11-19) Derivatives.In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 200-201. ISBN 978-952-92-5198-8.

[62] M. Scrima, A. Le Chevalier-Isaad, M. Grimaldi, Paolo Rovero, A.M. Papini, M. Chorev, A.M. D'Ursi. Conformational Preferences of Cyclopeptides Formed by i-to-i+4 Side Chain-to-Side Chain Cyclization via 1,4-Disubstituted [1,2,3]Triazolyl Moiety. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 266-267. ISBN 978-952-92-5198-8.

[63] A. Di Cianni, D. D’Addona, F. Rizzolo, A.M. Papini, M. Ginanneschi. On-resin microwaves-assisted ring closing metathesis for rapid synthesis of octreotide dicarba-analogues. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 274-275. ISBN 978-952-92-5198-8.

[64] F. Nuti, N. Qvit, F. Rizzolo, M. Hurevich, E. Peroni, M. Chelli, P. Rovero, C. Gilon, A.M. Papini. Microwave-Assisted Solid Phase Synthesis of Backbone Cyclic Glycopeptide Libraries. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 278-279. ISBN 978-952-92-5198-8.

[65] A.M. Papini. Peptide-based immunoassays for biomarkers detection: a challenge for translational research. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 438-439. ISBN 978-952-92-5198-8.

[66] F. Gori, B. Mulinacci, A.M. Papini, P. Rovero, A.G. Beck-Sickinger. Semi-synthetic approaches to glycosylation of MOG as autoantigen in Multiple Sclerosis disease. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 444-445. ISBN 978-952-92-5198-8.

[67] E. Innocenti, E. Peroni, F. Nuti, M. Chelli, P. Rovero, C. Selmi, A.M. Papini. Post translational modified peptide-based ELISA to detect autoantibodies in Primary Biliary Cirrhosis. In Peptides 2008: Chemistry of Peptides in Life Science, Technology and Medicine. Proceedings of the Thirtieth Peptide Symposium. H. Lankinen (Ed.) Published by Finnish Peptide Society in Finland in 2008, pp 470-471. ISBN 978-952-92-5198-8.

2009

[68] M.C. Alcaro, A. Carotenuto, F. Nuti, I. Paolini, E. Peroni, G. Sabatino, E. Novellino, F. Lolli, A.M. Papini, P. Rovero. Modified peptides for the diagnosis of autoimmune diseases. New Perspective in Medicinal Chemistry. S. Alcaro (Ed.). Pubblicato da Research Signpost, 607 Stanford Court, Irvine, CA, USA in 2009, Vol. 1:149-158. ISBN 978-81-308-0321-0

[69] E. Peroni, M. Tontini, B. Mulinacci, M. Chelli, F. Lolli, P. Rovero, A.M. Papini. A Glycopeptide-based Technique for Selective Antibodies Purification. In: Peptides for Youth The Proceedings of the 20th American Peptide Symposium. In Book Series: Advances in Experimental Medicine and Biology. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Published by Springer-Verlag New York in 2009, Vol. 611, pp. 369-370. DOI: 10.1007/978-0-387-73657-0

[70] M.A. Bonache, A. Le Chevalier, F. Nuti, E. Peroni, M. Chelli, P. Rovero, A.M. Papini. Ribose Building Block For The Synthesis Of Glycopeptides For Fishing Out Antibodies In Autoimmune Diseases. In: Peptides for Youth. The Proceedings of the 20th American Peptide Symposium. In Book Series: Advances in Experimental Medicine and Biology. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Published by Springer-Verlag New York in 2009, Vol. 611, pp. 441-442. DOI: 10.1007/978-0-387-73657-0

[71] F. Nuti, B. Mulinacci, E. Peroni, M.C. Alcaro, I. Paolini, F. Benedetti, A. Carotenuto, F. Ciolli, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. Studies for Identification of the Minimal Epitope(s) mimicked by the Synthetic Glucopeptide CSF114(Glc). In: Peptides for Youth. The Proceedings of the 20th American Peptide Symposium. In Book Series: Advances in Experimental Medicine and Biology. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Published by Springer-Verlag New York in 2009, Vol. 611, pp. 431-432.DOI: 10.1007/978-0-387-73657-0

[72] F. Gori, B. Mulinacci, E. Bonchi, M. Chelli, F. Lolli, A.M. Papini, P. Rovero. Semi-Synthetic Strategies to Obtain Glucosylated MOG to Identify Antibodies as Biomarkers in Multiple Sclerosis Disease. In: Peptides for Youth. The Proceedings of the 20th American Peptide Symposium. In Book Series: Advances in Experimental Medicine and Biology. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Published by Springer-Verlag New York in 2009, Vol. 611, pp. 327-328. DOI: 10.1007/978-0-387-73657-0

[73] F. Real-Fernández, A. Chamois-Colson, J. Bayardon, F. Nuti, E. Peroni, M.R. Moncelli, R. Meunier-Prest, S. Jugè, A.M. Papini. Synthesis Of Organometallic Glycopeptides And Electrochemical Studies To Detect Autoantibodies In Multiple Sclerosis Patients´ Sera. In: Peptides for Youth. The Proceedings of the 20th American Peptide Symposium. In Book Series: Advances in Experimental Medicine and Biology. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Published by Springer-Verlag New York in 2009, Vol. 611, pp: 435-436. DOI: 10.1007/978-0-387-73657-0

[74] S. Cantel, J.A. Halperin, M. Chorev, M. Scrima, A.M. D’Ursi, J.J. Levy, R.D. Di Marchi, A. Le Chevalier, P. Rovero, A.M. Papini. Side chain-to-Side chain Cyclization by Intramolecular Click Reaction - Building Blocks, Solid Phase Synthesis and Conformational Characterization. In: Peptides for Youth. The Proceedings of the 20th American Peptide Symposium. In Book Series: Advances in Experimental Medicine and Biology. S. Del Valle, E. Escher, W.D. Lubell (Eds.), Published by Springer-Verlag New York in 2009, Vol. 611, pp. 175-176. DOI: 10.1007/978-0-387-73657-0

2010

[75] S. Pandey, E. Peroni, M.C. Alcaro, F. Rizzolo, M. Chelli, P. Rovero, F. Lolli, A.M. Papini. Mimicry Effect of the Neo-Epitope [Asn⁶⁴¹(Glc)]FAN(635-655) with CSF114(Glc) Detecting Autoantibodies in Multiple Sclerosis. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 4-5. ISBN 0-9715560-5-9.

[76] C. Testa, S. Carganico, F. Nuti, M. Scrima, A.M. D’Ursi, M.L. Dirain, N. Lubin Germain, C. Haskell-Luevano, M. Chorev, P. Rovero, A.M. Papini. Stabilization of β Turn Conformation in Melanocortin-Like Peptide by Click Side Chain-To-Side Chain Cyclization. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 14-15. ISBN 0-9715560-5-9.

[77] G. Cane, A. Di Cianni, M. Lumini, AM. Papini, M. Ginanneschi. An Efficient MW-Assisted Synthesis of Dicarba-Analogues. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 184-185. ISBN 0-9715560-5-9.

[78] F. Rizzolo, F. Nuti, S. Pandey, M. Chelli, P. Rovero, A.M. Papini. Microwave-Assisted Solid Phase Synthesis of [Asn⁶⁴¹(Glc)]FAN(635-655): A New Case Study for Optimisation of Glycopeptide Synthesis. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 186-187. ISBN 0-9715560-5-9.

[79] F. Rizzolo, C. Testa, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Conventional and Microwave-Assisted SPPS Approach: A Comparative Study of PTHrP(1-34)NH₂ Synthesis. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 188-189. ISBN 0-9715560-5-9.

[80] M. Scrima, A.M. Papini, M. Chorev, A.M. D’Ursi. Molecular Dynamics Calculation and NMR Conformational Studies of Heterodetic Triazolyl Cyclo-Nonapeptides: A Comparative Study. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 220-221. ISBN 0-9715560-5-9.

[81] S. Pandey, D. Lambardi, F. Real-Fernández, M.C. Alcaro, E. Peroni, M. Chelli, A.M. Papini, F. Lolli, P. Rovero. Recognition of Cytoskeletal Proteins Monoclonal IgGs by CSF114(Glc), the Synthetic Probe of Multiple Sclerosis. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 290-291. ISBN 0-9715560-5-9.

[82] M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, C. Tiberti, A.M. Papini. Celiac Disease: Synthesis of Overlapping Linear Peptide Epitopes of tTG[Aa(1-230)]. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 492-493. ISBN 0-9715560-5-9.

[83] M. Di Pisa, G. Sabatino, M. Chelli, P. Rovero, C. Tiberti, A.M. Papini. Celiac Disease: Characterization of Amino Acids and Short Peptides Finger Print for a Fast I.V.D. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 494-495. ISBN 0-9715560-5-9.

[84] F. Real-Fernández, I. Passalacqua, E. Peroni, F. Lolli, P. Rovero, A.M. Papini. Characterisation of the Minimal Epitope Detecting Autoantibodies in Multiple Sclerosis by Surface Plasmon Resonance. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium. Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010 pp 498-499. ISBN 0-9715560-5-9.

[85] F. Gori, B. Mulinacci, L. Massai, F. Lolli, A.M. Papini, P. Rovero. Antigenic Probes for Autoantibody Detection in Multiple Sclerosis: Synthetic Peptides versus Recombinant Proteins. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010 pp 500-501. ISBN 0-9715560-5-9.

[86] S. Pandey, E. Peroni, P. Rovero, F. Lolli, M. Chelli, A.M. D’Ursi, A.M. Papini. Rational Design and Optimization of the Newly Designed Glycopeptide Sequence to Develop the Diagnostic/Prognostic Assay for Multiple Sclerosis. In: Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium.Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors). Prompt Scientific Publishing, San Diego, USA in 2010, pp 504-505. ISBN 0-9715560-5-9.

2012

[87] F. Nuti, F. Real-Fernandez, G. Rossi, S. Pandey, G. Sabatino, C. Tiberi, M. Larregola, S. Lavielle, J. Hayek, C. De Felice,P. Rovero, A.M. Papini. Autoantibodies to N-glucosylated peptide sequons in Rett syndrome: the first insight to disclose an autoimmune mechanism. In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012,pp432-433.ISBN 978-960-466-121-3.

[88] C. Rentier, F. Nuti, M. Chelli, G. Pacini, P. Rovero, C. Selmi, A.M. Papini. First synthesis of both pure diastereomeric N⁶-(1,2-dithiolane-(3R or S)-pentanoyl)-N²-Fmoc-L-Lys-OH for Fmoc/tBu SPPS. In: Peptides 2012.Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp626-627.ISBN 978-960-466-121-3.

[89] C. Rentier, O. Monasson, F. Nuti, P. Traldi, A. Lapolla, M. Larregola, P. Rovero, M. Chorev, A.M. Papini.^. Synthesis of glycated and glycosylated peptides to detect autoantibodies in diabetic patients’ sera. In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp186-187. ISBN 978-960-466-121-3.

[90] C. Tiberi, G. Sabatino, M. Di Pisa, G. Rossi, P. Rovero, A.M. Papini. SPPS of N-glucosylated Multivalent Epitopes to detect autoantibodies in Multiple Sclerosis patients’ sera In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp620-621. ISBN 978-960-466-121-3.

[91] G. Sabatino,. M. Di Pisa, F. Potenza, L. Rosi, L. Dei, A.M. Papini. Statistical analysis of amino acid fingerprint to characterize protein binders in works of art. In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp644-645. ISBN 978-960-466-121-3.

[92] M. Di Pisa, G. Sabatino, S. M. Chelli, P. Rovero, A.M. Papini. Design and synthesis of cross-linked peptide probes for the development of an in vitro diagnostics for Coeliac Disease In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp 630-631.ISBN 978-960-466-121-3

[93] S. Pandey, E. Peroni, I. Dioni, P. Rovero, A.M. Papini. From aberrant N-glucosylation to alpha actinin 1 as a new candidate autoantigen of an antibody mediated form of Multiple Sclerosis In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp16-17. ISBN 978-960-466-121-3.

[94] F. Rizzolo, C. Testa, D. Lambardi, M. Chorev, M. Chelli, P. Rovero, A.M. Papini. Fast and efficient microwave-assisted monitoring of difficult peptide sequences. In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp410-411.ISBN 978-960-466-121-3.

[95] O. Monasson, F. Rizzolo, P. Traldi, A. Lapolla, M Chorev, P.Rovero, A.M. Papini. Synthesis of the first Multivalent Epitope containing Nε-(1-deoxy-D-fructosyl)lysyl as diagnostic tool for diabetes In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium. G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp596-597. ISBN 978-960-466-121-3.

[96] C. Testa, D. D’Addona, M. Scrima,  A. M. D’Ursi, M. L. Dirain, M. Chorev, C. Haskell-Luevano, P. Rovero, A.M. Papini. Synthesis and in vitro activity examinations of 1,4-disubstituted-[1,2,3]triazolyl-containing cyclopeptides, analogs of MT-II, obtained via i to i+5 intramolecular side chain to side chain azide-alkyne cycloaddition.In: Peptides 2012. Proceedings of the Thirty-Second European Peptide Symposium.G. Kokotos, V. Constantinou-Kokotou, J. Matsoukas (Editors) European Peptide Society, Published by the University of Athens, Laboratory of Organic Chemistryin 2012, pp548-549. ISBN 978-960-466-121-3.

2014

[97] C. Rentier, G. Pacini, F. Nuti, E. Peroni, P. Rovero, A.M. Papini. Synthesis of diastereomeric building-blocks of lipoylated-Lysine and their use in SPPS. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp45-47. ISBN 978-619-90427-2-4.

[98] D. Petkova, B. Yanachkova, O. Monasson, A.M. Papini, I. Stoineva. Short Synthetic Peptides as Inhibitors of Angiotensin Converting Enzyme. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp 59-60. ISBN 978-619-90427-2-4.

[99] C. Rentier, O. Monasson, Z. Ferhat, F. Nuti, M. Larregola , E. Peroni, A.M. Papini. Methionine oxidation in the tetradecapeptide CSF114(8-21).A case of study. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium.Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp69-70. ISBN 978-619-90427-2-4.

[100] S. Pascarella, F. Melani, L Giovannelli, A.M. Papini, P. Rovero. Molecular modelling assisted design of a TASP mimicking SERPINH1 chaperone function in collagen biosynthesis. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium.Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp152-153. ISBN 978-619-90427-2-4.

[101] S. Pascarella, C. Tiberi, L. Giovannelli, L. Pino, A.M. Papini, P. Rovero. Design, synthesis and biological activity evaluation of peptides as collagen turnover modulators for cosmeceutical purpose. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium.Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp242-243. ISBN 978-619-90427-2-4.

[102] C. Rentier, G. Rossi, F. Nuti, E. Peroni, A. Lapolla, P. Traldi, P. Rovero, A.M. Papini. Synthesis and evaluation of kynurenine-containing peptides as diagnostic tools for Multiple Sclerosis. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium.Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp262-263. ISBN 978-619-90427-2-4.

[103] G. Rossi, F. Real-Fernández, F. Panza, F. Pratesi, P. Migliorini, A.M. Papini, P. Rovero. SPR-based biosensor analysis of autoantibodies from Rheumatoid Arthritis patients’ sera interacting with citrullinated Multiple Antigen Peptides. In: Peptides 2014.Proceedings of the Thirty-Third European Peptide Symposium. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp266-267. ISBN 978-619-90427-2-4.

[104] F. Real-Fernández,  G. Rossi, F. Niccheri, M. Ramazzotti, D. Degl'Innocenti, F. Lolli, A.M. Papini, P. Rovero. Surface Plasmon Resonance to Select and Characterize Recombinant Human Domain Antibodies. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium.Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp268-269. ISBN 978-619-90427-2-4.

[105] G. Pacini, C. Rentier, F. Nuti, E. Peroni, F. Real Fernàndez, P.M. Battezzati, C. Selmi, P. Rovero, A.M. Papini. Aberrant post-translational modifications and autoimmunity: the case of Primary Biliary Cirrhosis. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp 270-271. ISBN 978-619-90427-2-4.

[106] G. Pacini, M. Ieronymaki, M. Larregola, F. Burlina, S. Lavielle, J. Offer, P. Rovero, A.M. Papini. Semi-synthetic strategy to obtain aberrantly N31-glucosylated Myelin Oligodendrocyte Glycoprotein. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014 pp 290-291. ISBN 978-619-90427-2-4.

[107] V. Doan, G. Chaume, A. Bordessa, F. Rizzolo, E. Peroni, A.M. Papini, S. Kara, S. Afonin, A.S. Ulrich, and T. Brigaud. Solid Phase Peptide Synthesis Of A 19F-Labeled Harzianin: An Antimicrobal Peptaibol. In: Peptides 2014. Proceedings of the Thirty-Third European Peptide Symposium. Emilia Naydenova, Tamara Papainova, and Dancho Danalev (Editors). Printed in Bulgaria by BULGARIAN PEPTIDE SOCIETY in 2014, pp 362-363. ISBN 978-619-90427-2-4.

2015

[108] Rentier C, Pacini G, Nuti F, Rovero P, Papini AM. Lipoylated peptides and proteins. In: Peptidomimetics II. Top Heterocycl Chem 2017, 49:235-252. DOI: 10.1007/7081_2015_186

Pubblicato da Springer International Publishing Switzerland, First online: 30 October 2015

INVITED LECTURES in UNIVERSITIES, RESEARCH CENTRES AND NATIONAL AND INTERNATIONAL CONGRESSES

Anna Maria Papini

2000-2021

[Inv1] IL1 – 1st Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 1-3, 2000. March 1, 2000: Lecture invited by the Chair Prof. J. Matsoukas. Title: Synthesis of post-translational modified peptide and non-peptide analogues of MBP/MOG myelin antigens in multiple sclerosis research.

2001

[Inv2] IL2 - 2nd Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 1-3, 2001. March 1, 2001: Lecture invited by the Chair Prof. J. Matsoukas e Prof. P. Cordopatis. Title: Specific role of Asn(Glc) in autoantibody recognition to glycosylated peptides: towards new immunotherapeutic drugs for the treatment of Multiple Sclerosis.

2002

[Inv3] PL1 - 3rd Conference“Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras, Greece, March 7-9, 2002. March 7, 2002: Plenary “Memory Lecture in Honour of Marco Vergelli for his contributions to Multiple Sclerosis Research” invited by the Chairs Prof. J. Matsoukas and Prof. P. Cordopatis. Title: A very promising Cyclic MBP Peptide for Multiple Sclerosis.

[Inv4] PL2 -European Commission-funded Intensive Course: “Synthesis for Solving Biological Problems”,Henderson Hall,Newcastle upon Tyne (United Kingdom), August 3-10, 2002. August 3, 2002: Plenary Lecture invited by the Chair Prof. Bernard Golding. Title: Synthesis of post-translationally modified peptidesof myelin proteins. The contribution of bioorganic chemistry to the diagnosis and immunotherapy of the autoimmune disease multiple sclerosis ».

2003

[Inv5] S1 - Institut de Biologie Moléculaire et Cellulaire, Strasbourg (France). Seminar invited by Dr. Jean-Paul Briand, February 21, 2003, h. 9 :30, Salle des Séminaires. Title: CSF114(Glc): the glycopeptide detecting autoantibodies in multiple sclerosis. MS PepKit, the first diagnostic test to follow-up the disease activity.

[Inv6]: S2- INSERM E209, Hôpital Saint-Antoine, Bâtiment Raoul, Paris (France). Seminar invited by Dr. Claude Carnaud, June 23, 2003. Title: Contribution of peptide chemistry to study the autoimmune disease multiple sclerosis.

[Inv7]: S3- Journée de l’Ecole Doctorale: Du Matériau à l’Interface Chimie-Biologie, Université de Paris-Sud, Bâtiment 338, Paris (France). Seminar invited by Prof. Yves Langlois, September 19, 2003. Title: Contribution de le chimie bioorganique à l’étude d’une pathologie auto-immune: cas de la sclérose en plaque.

[Inv8] S4- 1st Pratical Training Course “Innovative combinatorial approaches and technologies”, ComGenex, Budapest (Hungary) & Polo Scientifico, Università di Firenze, Firenze (Italy), April 9-11, 2003. April 11, 2003: Seminario su invito del Dr. Ferenc Darvas, ComGenex, Budapest. Title: A combinatorial approach for the rational design of innovative diagnostic tools for autoimmune diseases.

[Inv9] IL3 - Italian-German Mini Symposiumon Peptides and Proteins. “Structure and Molecular Recognition”, Max Planck Institut für Biochemie, Kleiner Hoersaal, Bauteil T, Martinsried (Germany). December 5, 2003: Lecture su invito del Prof. Luis Moroder. Title: Development of the innovative designed glycopeptide CSF114(Glc) as prognostic tool for the characterizationof an antibody-mediated multiple sclerosis subgroup.

2004

 [Inv10] IL4 - 5th Conference “Medicinal Chemistry: Drug Design and Development”, Conference and Cultural Centre, University of Patras (Greece), March 11-13, 2004. March 11, 2014: Lecture su invito del Chair Prof. J. Matsoukas. Title: Development of the innovative designed glycopeptide CSF114(Glc), as prognostic tool for the characterization of an antibody-mediated multiple sclerosis subgroup.

[Inv11] IL5 - 9th Naples Workshop, Peptides as Therapeutic, Diagnostics & Vaccines, Villa Orlandi, Anacapri (Italy), May 8-11, 2004. May 9, 2004: Lecture su invito del Chair Prof. Ettore Benedetti. Title: Peptide-based immunoassays for the diagnosis of autoimmune diseases.

[Inv12] S5 - Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon (France), June 11, 2004 : Seminario su invito del Prof. Sylvain Jugé. Title: Solid-phase strategy to cyclic structures.

[Inv13] S6- D.E.A (Diplôme d’Etude Avancés): Microbiologie-Enzymologie-Nutrition (Aspects Moléculaires et Cellulaires), Magistére Microbiologie-Enzymologie (3éme année). Module Biophysique et Biologie Structurale, Université Henry Poincare, Nancy 1, Faculté des Sciences et Techniques, Nancy (France), December 3, 2004 : Seminario su invito del Dr. A. Aubry e dal Prof. B. Vitoux. Title : Peptides portants des modifications post-traductionnelles pour le diagnostic et la thérapie de pathologies autoimmunes.

2005

[Inv14] S7 - Weizmann Institute of Science, Rehovot (Israel), January 18, 2005: Seminario su invito del Prof. M. Sela (Past President del Weizmann Institute e inventore del farmaco Copolymer1. Title: Glycosylated synthetic probes to detect disease-specific autoantibodies, biomarkers of Multiple Sclerosis.

[Inv15] IL6 – 4thEuropean-Japanese Bioorganic Meeting & Chemical Biology COE Program sponsored by Okayama University, Hotel Limani, Ushimado, Setoucvhi, Okayama-Pref. (Japan), March 15-19, 2005. March 17, 2005: Lecture su invito del Prof. Tetsuo Toraya. Title: CSF114(Glc): the first synthetic glycopeptide probe to follow-up disease acrivity in Multiple Sclerosis patients.

[Inv16]S8- Seminaris del Parc Cientific de Barcelona 2005, Universitat de Barcelona (Spain),  May 19, 2005: Seminario su invito del Prof. Fernando Albericio. Titolo: A combinatorial approach for the rational design of innovative prognostic tools for multiple sclerosis.

[Inv17] S9 - Laboratoire de Synthése et Electrosynthése et Organométalliques UMR CNRS 5188 Faculté des Sciences, Dijon (France), May 2, 2005 : Seminario su invito del Prof. Claude Moise. Title: Les bases de la synthése peptidique.

[Inv18] S10 - Conférences de l’Institut de Chimie des Substances Naturelles, CNRS-UPR2301, Bâtiment 27, Gif-sur-Yvette (France), 7 Julliet, 2005 : Seminario su invito del Direttore dell’ICSN Prof. Jean-Yves Lallemand. Title: Les glycopeptides pour le développement de tests prognostiques innovatifs pour suivre la sclérose en plaque: vers un traitement thérapeutique nouveau.

2006

[Inv19]: S11– Doctorate School in Chemical Sciences, Università di Siena. Symposium on Metal Ions and Neurodegeneration,Scientific Campus of S. Miniato, Via A. Moro, Siena Room 14. January 31, 2006: Seminario su invito dellla Prof. Elena Gaggelli a nome del Collegio dei Docenti del Dottorato. Title: Aberrant glucosylation triggering autoimmunity in multiple sclerosis.

[Inv20]IL7- Symposium on Recent Advances in Synthesis and Chemical Biology V. Center for Synthesis and Chemical Biology. O'Flanagan Theatre, Royal College of Surgeons in Ireland (RCSI), Dublin (Ireland), December 15, 2006: Lecture su invito del Prof. Kevin B. Nolan. Title: An Innovative Chemical Reverse Approach to the Discovery of Specific Biomarkers of Autoimmune Diseases.

 [Inv21] IL8 - 7th Conference “Medicinal Chemistry: Drug Design and Design”, Conference and Cultural Centre, University of Patras (Greece), March 8-11, 2006. March 9, 2016: Lecture su invito del Chair Prof. J. Matsoukas. Title: Diagnostics and Prognostic Tools in Multiple Sclerosis.

2007

[Inv22] PL3- Israeli-Italian Bi-National Conference Brain functions: from Basic Reasearch to clinical Applications, Weizmann Institute of Science, Rehovot (Israel), March 14, 2007: Plenary Lecture su invito del Prof. M. Tsodyks. Title: A chemical reverse approach to biomarkers of neurological disorders.

[Inv23]S12- Department of Biological Chemistry, Judea & Samaria College, Ariel (Israel),March 15, 2007:Seminario su invito del Dr. Gary Gellerman. Title: An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis from follow-up of disease activity to specific therapeutic treatments.

[Inv24] PL4- The 6^th Congress of the Israeli association for Medicinal Chemistry, Weizmann Institute of Science, Rehovot (Israel), March 18, 2007:First Plenary Lecture su invito del Prof. M. Fridkin. Title: A chemical Reverse Approach to detect biomarkers of autoimmune diseases. Notizia riportata nel Bulletin of the Israel Chemical Society N. 23/January 2008.

[Inv25] S13- Bar-Ilan University, Department of Chemistry,Ramat-Gan (Israel), Special Seminar March 19, 2007:Seminario su invito del Prof. Gerardo Byk. Title: Optimized synthetic strategies to glycopeptides for the development of a diagnostic/prognostic test for Multiple Sclerosis.

[Inv26]S14- Istituto di Biofisica- Unità Operativa di Pisa. Area Ricerca Pisa- S. Cataldo, Pisa (Italy). May, 2, 2007: Seminario su invito del Dr. Santi Chillemi. Title: A chemical reverse approach to decte autoantibodies as biomarkers of autoimmune diseases.

[Inv27] IL9 - Modern Solid Phase Peptide Synthesis & its applications. An official satellite meeting of the 7^th International Australian Peptide Symposium, Port Douglas (Australia), October 17-20, 2007. October 18, 2007: Lecture su invito del Prof. J. Wade. Title: N-Triazinylammonium coupling reagents: from the concept of superactive esters to a versatile assistance for peptide synthesis.

[Inv28]S15 - Howard Florey Institute, University of Melbourne, Melbourne (Australia), October 29, 2007: Seminario su invito del Prof. John Wade. Title: An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis: from an efficient follow-up of disease activity to a guide for specific therapeutic treatments.

[Inv29] S16 - Burnet Institute, Austin Campus, Heidelberg (Australia), October 31, 2007. Seminario su invito della Prof. V. Apostolopoulos. Title: Strategies for characterisation of a Multiple Sclerosis pattern disease based on specific autoantibodies as biomarkers.

2008

[Inv30] IL10 - Third ERA Chemistry Flash Conference: Carbohydrates at the interfaces of biology, medicine and materials science. ERA-Chemistry “A Network of research councils for the development and implementation oif joint bottom-up European programmes for curiosity driven research”, Embarkinitiative, Killarney (Ireland), 9-13 March, 2008. March 13, 2008: Lecture su invito del Prof. S. Oscarson e dal Prof. P. Murphy. Title: Aberrant glycosylations as biomarkers of autoimmune diseases correlating with disease activity: toward the development of reliable diagnostic/prognostic tools.

[Inv31] AL1 - 6^th Hellenic Forum on Bioactive Peptides, The Conference and Cultural Centre of the University of Patras (Greece), May 18-20, 2008. May 18, 2008: 1st Dimitrios Theodoropoulos Memorial Lecture Award by the Hellenic Peptide Society to A.M. Papini in recognition of her significant contribution to the advancement of peptide science and especially in peptide chemistry. Title: A “Chemical Reverse Approach” to modified peptides as synthetic antigenic probes to detect autoantibodies as biomarkers of multiple sclerosis.

[Inv32] IL11 - 5th Bulgarian Peptide Symposium, Rila Mountain (Bulgaria), 28-30 May 2008. May 30, 2008:Lecture su invito del Prof. L. Vezenkov. Title: Post-translationally modified peptides to develop reliable diagnostic/prognostic assays to follow up autoimmune diseases.

[Inv33] AL2 - 30th European Peptide Symposium 31 Agosto-5 Settembre  2008, Helsinki (Finland). 31 Agosto 2008: Leonidas Zervas Memorial Lecture Award 2008attributed by the European Peptide Society to A.M. Papini for her outstanding achievements in peptide science (in commemoration of L. Zervas and the outstanding contributions he made to peptide chemistry nominated by the European Peptide Society). Title: Peptide-based immunoassays for biomarkers detection: a challenge for translational research.

[Inv34] S17- Istituto Clinico Humanitas Centro di Ricerca e Didattica, Rozzano, Milano (Italy). December 17, 2008: Seminario su invito del Prof. Carlo Selmi. Title: A Chemical Reverse Approach to Detect Biomarkers of Autoimmune Diseases: a Challenge for Translational Research.

[Inv35] IL12 – 6th International Microwaves in Chemistry Conference, Cambridge Mariott@MIT, Cambridge, MA (USA), May 13-16, 2008. May 14, 2008: Lecture su invito del Prof. Stephen L. Buchwald, Camille Dreyfus Professor. Title: Optrimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostic/prognostic immunoassays.

2009

[Inv36] S18 - Barcelona Biomedical Research Park PRBB-CRG Seminar, Pompeu Fabra University, Barcelona (Spain). February 23, 2009: Seminario su invito del Prof. David Andreu.Title: Peptide-based Immunoassays for Biomarkers Detection: a Challenge for Translational Research.

[Inv37] S19 -Master di II livello in “Progettazione e Sviluppo di Farmaci”. Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici. Università degli Studi di Pavia (Italy). April 17, 2009: Lecture su invitodella Prof. Ornella Azzolina.Title: Recenti progressi nella sintesi di peptidi d’interesse biomedico.

[Inv38] PL5 - MAOPS, International Symposium on Microwave-Assisted Organic and Peptide Synthesis 2009, La Grande Motte (France). June 4-5, 2009. June 4, 2009: Plenary Lecture su invito del Dr. Gilles Subra.Title: Optimised strategies for the synthesis of biomolecules: the microwave approach to complex peptides for diagnostics.

[Inv39] PL6 - 11th International Congress on Amino Acids, Peptides and Proteins, Vienna (Austria). August 3-7, 2009. August 6, 2009: Prominent speaker e Plenary Lecture su invito del Prof. Norbert Sewald.Title: Glycated and glycosylated amino acids for Solid-Phase GlycoPeptide Synthesis: a challenge to microwave-assisted strategies for R&D diagnostics of autoimmune diseases.

[Inv40] PL7 – Fundacion BBVA – IRB Barcelona BioMed Conference on “Peptide engineering: Therapeutic peptides”, October 26-28, 2009. October, 28, 2009: Plenary Lecture su invito del Prof. Ernest Giralt e del Prof. Claudio Toniolo.Title: Click chemistry reaction: a challenge for peptide engineering to develop efficient drugs and diagnostics.

[Inv41] IL13 - Does size matter? Beyond small molecule therapeutics: challenges and success stories”, Université Libre de Bruxelles, Salle Dupéel, Avenue Jeanne 44, Brusselles (Belgium). November 6, 2009: Distinguished speaker su invito del Dr. Edmond Differding (President of the Medicinal Chemistry Division, SRC) e del Prof. Koen Augustyns (President, Division for Medicinal and Bioorganic Chemistry, KVCV).Title: Synthetic post-translationally modified peptides for the discovery of new biomarkers of autoimmune diseases: a “Chemical Reverse Approach”.

[Inv42] S20 - Prefectural University of Osaka (Japan). November 12, 2009: Seminario su invito del Prof. Ikuo Fujii.Title: Post-translationally modified peptides for detection of biomarkers of immune-mediated diseases: A “Chemical Reverse Approach”.

2010

[Inv43] PL8 - XII Convegno-Scuola sulla Chimica dei Carboidrati, Gruppo Interdivisionale Chimica dei Carboidrati della S.C.I. Pontignano (Siena). June 20-23, 2010. June 21, 2010: Plenary Lecture su invito del Prof. Michelangelo Parrillo a nome del comitato scientifico. Title: Glycated and glycosylated amino acids for solid-phase glycopeptide synthesis: a challenge for R&D diagnostics of neurodegenerative diseases.

[Inv44] S21 - Université de Versailles, Saint Quentin en Yvelines (France). November 4, 2010: Seminario su invito del Prof. Francois Couty.Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[Inv45] IL14 - Juvenil Diabetes Research Foundation Workshop “Role of Beta Cell Antigen Modifications in the Pathogenesis of T1D and their Diagnostic and Therapeutic Potential”,New York (USA). December 13th, 2010: Lecture su invito del Comitato scientifico. Title: A “Chemical Reverse Approach” to detect autoantibodies as biomarkers of autoimmune diseases: a challenge for theragnostics.

2011

[Inv46] S22 - iBiTec-S, CEA/Saclay, Gif sur Yvette (France). January 25, 2011: Seminario su invito del Dr. Bernard Rousseau. Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics".

[Inv47] S23 - ICOA - UMR 6005 / Université d'Orléans, Orleans (France). March 30, 2011: Seminario su invito del Prof. Patrick Rollin. Title: Chemical approaches to modulate peptide secondary structures inducing specific biological recognition.

[Inv48] S24- Lezione per il Cycle thématique dell’Université de Cergy-Pontoise "Dynamiques  des systèmes complexes: Modélisation de macromolécules biologiques", St  Martin, Université de Cergy-Pontoise (France).March 31, 2011: invitata dall’organizzatore Prof. Roberto Livi. Title: 3D structures mimicking protein biological activity: from a rational design to peptide-based diagnostics and therapeutics.

[Inv49] S25 - Master 2nd level “Progettazione e Sviluppo di Farmaci: Attualità nella Ricerca Farmaceutica Farmaci peptidici e peptoidici”. Università degli Studi di Pavia, Pavia (Italy). April 15, 2011: Seminario su invito della Prof. Ornella Azzolina.Title: “Approcci sintetici per indurre strutture secondarie e modulare l'attività biologica di peptidi.

[Inv50] S26– Neonatology and beyond, Sala Universitaria - Palazzo Granafei Nervegna, Brindisi (Italy). 14 Maggio 2011: Seminario su invito del Chair Dr. Giuseppe Latini. Title: Ricerca di biomarcatori nelle malattie mediate dal sistema immunitario. Corso di aggiornamento per attribuzione di crediti ECM.

[Inv51] S27- Ecole Doctorale, Université de Montpellier (France). May 26, 2011 : Seminario su invito del Doyen de la Faculté de Pharmacie Prof. Jean Martinez. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[Inv52] IL15- Italian-German Meeting: Green and SustainableApproach to Process Intensification, Torino (Italy), 2-3 June 2011. June 3, 2011: Lecture su invito del Chair Prof. Giancarlo Cravotto. Title: Efficient synthetic strategies aimed to R&D of diagnostics.

[Inv53] S28INSERM U829, Laboratoire SABNP "Structure-Activité des Biomolécules Normales et Pathologiques" Université d'Evry-Val d'Essonne (France). June 7, 2011: Lecturesu invito del Prof. Flavio Toma. Title : A « Chemical Reverse Approach » to develop efficient diagnostic/prognostic assays for immune-mediated diseases.

[Inv54] IL16- Gordon Research Conference – Carbohydrates, Colby College, Waterville, ME (USA), June 19-24, 2011. June 21, 2011: Lecturesu invito dei Chair Robert J. Woods and Nicola Pohl.Title: The “Chemical Reverse Approach” to develop glycopeptides as synthetic antigens characterising autoantibodies as biomarkers of neurodegenerative diseases. https://www.grc.org/carbohydrates-conference/2011/

[Inv55] S29 - Dipartimento di Scienze della Vita, Università degli Studi di Trieste, Trieste (Italy). July 25, 2011: Seminario su invito delDirettore del Dipartimento di Scienze della Vita Prof. Renato Gennaro.Title: A « Chemical Reverse Approach » to develop efficient and reliable diagnostics for immune-mediated diseases.

2012

[Inv56] IL17 Gordon Research Conference: Peptides, Chemistry & Biology of Peptides as Signals, BioMaterials and Therapeutics. Ventura Beach Marriott, Ventura, CA (USA) February 19-24, 2012.February 21, 2012: Discussion Leader su invito dei Chairs Prof. Fred R. Naider eMaria A. Bednarek. Session: Peptide Vaccines.

[Inv57] PL9 1^st See-Drug Workshop From chemical to systems biology – Peptide synthesis and protein production May 9-10, 2012, Patras (Greece). May 9, 2012: Plenary Lecture su invito del Chair Prof. Georgios A. Spyroulias. Title: The importance of a “chemical reverse approach” to modulate secondary structures inducing specific and high affinity biological recognition.

[Inv58] S30- Scuola di Dottorato, Aula 1, Edificio E della Presidenza della Facoltà di Scienze dell'Università di Pisa, Via Buonarroti 1, Pisa (Italy). May 28, 2012: Seminario su invito della Dr. Federica Chiellini. Title: Problem solving in diagnostics of immune-mediated diseases: a Chemical Reverse Approach.

[Inv59] KL1 - 13th Naples Workshop on Bioactive Peptides. Conformation and activity in peptides: relationships and interactions, Aula Magna Partenope, Napoli (Italy), June 7-9, 2012. June 9, 2012: Keynote Lecture su invito dei Chair Prof. Giancarlo Morelli e Dr. Michele Saviano. Title: The mimicry pathway from glycopeptides to specific protein antigens of autoimmune neurodegenerative diseases. http://www.cirpeb.unina.it/naples2012/NW2012.pdf

[Inv60] PL10- Saxon Biotechnology Symposium, Centre for Biotechnology and Biomedicine (BBZ), Universitaet Leipzig and Biotechnology Center (BIOTEC) of the Technical University of Dresden, Deutscher Platz 5, 01403 Leipzig (Germany), June 20, 2012: Plenary Lecture su invito della Direttrice del Biotechnologisch-Biomedizinisches Zentrum, Prof. Dr. Andrea Robitzki. Title: Post-translational modified peptides to develop efficient IVD to follow up disease activity of autoimmune diseases: a challenge for theragnostics. http://www.biotec.tu-dresden.de/fileadmin/press/press-releases/12.06.20._Saechischer_Biotechnologietag.pdf

[Inv61] IL18- 32nd European Peptide Symposium, Athens (Greece), September 2-7 2012. September 7, 2012: Lectureinvited by the Chair Prof. George Kokotos. Title: The mimicry pathway from anti-glycopeptide antibodies to specific protein antigens of immune-mediated neurodegenerative/neuroregressive diseases: the case study of Rett syndrome.

[Inv62] IL19 - 2nd Austrian Peptide Symposium, Vienna (Austria). November 29 2012:Lectureinvited by the Chair Prof. Christian F.W. Becker and Dr. Christian Gruber. Title: Post-translationally modified peptides detecting autoantibodies as biomarkers of neurodegenerative diseases: A challenge for theragnostics of immune-mediated diseases.

[Inv63] S31- Département de Chimie, Faculté des arts et des sciences, Université de Montreal (Québec), Salle 1035, Pavillon J.-A. Bombardier. December 12, 2012: Seminar invited by Prof. William D. Lubell and Prof. Joelle Pelletier. Title: A “Chemical Reverse Approach” to Modulate Peptide Secondary Structures Inducing Specific and High Affinity Biological Recognition. http://www.calendrier.umontreal.ca/detail/155102

2013

[Inv64] S32- Karlsruhe Institute of Technology , Department of Molecular Biophysics at the Institute of Biological Interfaces, Karlsruhe (Germany).January 21, 2013: Seminar invited by Prof. Dr. Anne S. Ulrich. Title: Peptide secondary structures modulating biological recognition: a “chemical reverse approach”.

[Inv65]PL11- 22nd Polish Peptide Symposium, Kudowa Zdroj (Poland), September 1-5, 2013. September 4, 2013: Plenary Lecture invited by the Chairman Prof. Rafal Latajka. Title: Autoimmunity and Neurodegeneration: the Mimicry Pathway From Aberrant N-glucosylated Peptides to Specific Protein Antigens.

2014

[Inv66] IL20 Gordon Research Seminar (GRS): Chemistry & Biology of Peptides: Recent Advances in the Peptide Chemistry Toolbox, Ventura Beach Marriott, Ventura, CA (USA), February 22-23, 2014. February 22, 2014: Discussion leader invited by the Chairs Charles J. Bowerman and Neha Garg for the Session title: “Pushing the Boundaries of Peptide Methodology and Application”.https://www.grc.org/chemistry-and-biology-of-peptides-grs-conference/2014/

[Inv67] IL21 Hungarian Peptide Symposium, 28-30 May, 2014, Lake Balaton (Hungary). May 28, 2014: Lecture su invito del Chair Prof. Gabor Mezo. Title: Post-translationally modified peptides to develop efficient IVDs to follow up disease activity: a challenge for theragnostics of autoimmune diseases.

[Inv68] KL2 - 14^th Naples Workshop on Bioactive Peptides “The Renaissance era of Peptides in Drug Discovery”, Aula Magna Partenope, Centro Congressi “Federico II”,Napoli (Italy), 12-14 June 2014. June 13, 2014: Keynote Lecture su invito dei Chair Prof. G. Morelli, Dr. M. Saviano e Prof. Paolo Grieco. Title: From an N-glucopeptide synthetic probe to an hyper-glucosylated protein antigen: a bacterial infection triggering and antibody mediated form of multiple sclerosis?

[Inv69] IL22 - First European Workshop on Tolerogenic Vaccination in Autoimmune Diseases, University of Piemonte Orientale “Amedeo Avogadro” Aula Magna, Via Solaroli 17, 28100 Novara (Italy). November 20, 2014: Lecture su invito dei Chair Prof. Umberto Dianzani e Prof. John Matsoukas. Title: Glycopeptides and immune response.

2015

[Inv70] S33 - Technische Universität München, Emil Erlenmeyer Forum 5, Freising, Weihenstephen (Germany). June 2, 2015: Seminario su invite della Prof. A. Kaporniotu. Title: A “Chemical Reverse Approach” to Modulate Peptide Secondary Structures Inducing Specific and High Affinity Biological Recognition.

[Inv71] IL23 -International Joint Israel-Greek-Italian Neuroimmunology Meeting, Elounda, Crete (Greece), June 11-14, 2015. 13 June 2015. Lecture su invito del Chair Prof. Dimitrios Karussis. Title: From synthetic glycopeptides to the discovery of bacterial proteins cross-reacting with anti-N-glucosylation antibodies in Multiple Sclerosis.

[Inv72] PL1223rd Polish Peptide Symposium August 30 – September 3, 2015. Hotel Zacisze Piłsudskiego 97-215 Spała (Poland). September 1, 2015: Plenary Lecture su invito della Chair Prof. Beate Kolesinska. Title: Strategies for modulation of secondary structures to optimise biological recognition.

[Inv73] IL24 - 15th International Conference on Microwave and High Frequency Heating AMPERE 2015, Carocow (Poland), September 14-17, 2015. September 16, 2015: Lecture su invito del Chairman Dariusz Bogdal. Title: The challenge of MW-assisted solid-phase peptide synthesis: R&D of peptide-based diagnostics.

2016

[Inv74] IL25 Gordon Research Seminar (GRS): Chemistry & Biology of Peptides: Peptides and Petidomimetics: Inspired by Nature and Applied by Scientists, Ventura Beach Marriott, Ventura, CA (USA), February 20-21, 2016. February 20, 2016: Discussion Leader su invito dei Chair Neha Garg e Astrid Knuhtsen per la Sessione “Peptides in Infectious Diseases”.https://www.grc.org/chemistry-and-biology-of-peptides-grs-conference/2016/

[Inv75] S34 - Department of Biology, Technische Universität Darmstadt (Germany). July 7, 2016:Seminario su invito della Prof. Maria Cristina Cardoso. Title: From an N-glucosylated peptide to a bacterial protein involved in triggering autoantibodies in Multiple Sclerosis and Rett Syndrome

[Inv76] S35UMR CNRS BioCIS – Unité Mixte de Recherche CNRS BioCIS (Biomolécules: Conception, Isolement, Synthèse), Faculté de Pharmacie, Université Paris-Sud, Chatenay-Malabry (France). October 13, 2016: Seminario su invito del Direttore Dr. Bruno Figadère. Title: Antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

[Inv77] PL13 - Theo Murphy International Scientific Discussion meeting, The Royal Society “Self-assembled peptides: from nanostructure to bioactivity” Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ (UK), October 24-25, 2016. October 25, 2016: Plenary Lecture su invito dei Chair Prof. Dek Woolfson e Prof. Louise Serpell. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens. Tape record of the talk: http://downloads.royalsociety.org/events/2016/10/self-assembled-peptides/Papini.mp3

[Inv78] S36 - IBB - Istituto CNR di Biostrutture e Bioimmagini, Sezione di Catania (Italy), December 6, 2016: Seminario su invito del Direttore dell’IBB Dr. Marcello Mancini e del Direttore della Sezione di Catania Dr. Giuseppe Pappalardo. Title: Autoimmunity and neurodegeneration. The mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens, antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

2017

[Inv79] PL14SECO 54 – 54th Edition of the « Semaine d’Etudes en Chimie Organique », May 7-13 2017, Saint Martin de Londres, Hérault (France). May 9, 2017: Plenary lecture su invito del Dr. Kévin Fauché a nome del Comitato organizzatore. Title : Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific protein antigens.

[Inv80] PL15- 24th Polish Peptide Symposium on the occasion of the 50th anniversary of the first meeting of Polish scientists working in the field of peptides, Jastrzębia Góra, Gdańsk (Poland), September 3-7, 2017. September 5, 2017: Plenary lecture su invito della Chairperson Prof. Sylwia Rodziewicz-Motowidło per la “Session dedicated to the memory of Dr. K. Bankowski: Peptide and peptidomimetics synthesis”. Title: Cosmeceuticals behind the secret of youth: a peptide point view.

2018

[Inv81] S37 - Technische Universität München, Emil-Erlenmeyer-Forum 5, Freising-Weihenstephen, January 9, 2018: Seminario su invito della Prof. Dr. Aphrodite Kapurniotu. Title: Peptides in the pharmaceutical market: state-of-the art and perspectives.

[Inv82] S38 - Center of Evolutionary Chemical Biology, Department of Chemistry & Nano Science Center, University of Copenhagen, January 11, 2018: Seminario su invito del Prof. Dr. Morten Meldal. Title: Antibodies from Multiple Sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus Influenzae.

[Inv83] S39Corso di specializzazione per attribuzione ECM “Endocrine Disrupting Chemicals and Developmental Origins of Health and Disease”, Reggio Emilia (Italy), 23 Febbraio 2018: Seminario su invito della Chair Prof. Maria Street come moderatore della IV sessione: Nuovi supporti per la ricerca.

[Inv84] KL3 - RiminiPeptides 2018: “Peptides and conjugates for tumor targeting, therapy and diagnosis:, June 16-18, 2018 Rimini (Italy). June 17, 2018: Keynote Lecture su invito del Chair Prof. Dr. Norbert Sewald. Title:Exotic side chain-to-side-chain cyclization modes in octreotide analogs for tumor pretargeting.

[Inv85] KL4 - EuroChemistry Conference 2018 June 11-13, 2018 Rome, Italy. June 11, 2018: Keynote lecture su invite del Chair Dr. Steven J. Soldin. Title: Autoimmunity and neurodegeneration: the mimicry pathway from aberrant N-glucosylated peptides to specific bacterial antigens.

[Inv86] S40 - Wroclaw University of Technology, Zakład Technologii Organicznej i Farmaceutycznej Wydział Chemiczny (Poland), June 28, 2018: Seminario su invito del Prof. Dr. Rafal Latajka. Title: "Peptides and conjugates for tumor targeting, therapy and diagnosis: the wonderful world of click chemistry".

[Inv87] PL16 -International Workshop & Summer School “Mass spectrometry in Medical Technology and Biotechnology” Int. MSc Course “Medizintechnik/ Medical Technology”, Rhein Main University, Rüsselsheim am Main (Germany), August 19-25, 2018. August 19, 2019: Plenary opening Lecture su invito del Prof. Dr. Michael Przybylski. Title: “A chemical approach to identify peptide epitopes for high affinity antibodies in autoimmune diseases”.

[Inv88] IL26EuroPEPTIDES 2018 part of Tides Europe: Peptide Discovery and Drug Development Strategies, Postillion Hotel Amsterdam, Paul Van Vlissingenstraat 8, NL – 1096 BK Amsterdam (NL), November 6-8, 2018. November 6, 2018: Lecture su invite del Dr. Waleed Danho. Title: “New Modalities and peptide drug development strategies”.

[Inv89] IL27 –10th International Peptide Symposium, ROHM Theatre Kyoto and Miyako Messe (Japan), December 3-7, 2018. December6, 2018: Lecture su invito del Chair Prof. Shiroh Futaki. Title: “Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae”.

2019

[Inv90] S41 - L. LEKARSKA FAKULTA, Univerzita Karlova, Large meeting room of Dean’s Office Building, Praha (Tchek Republic), March 19, 2019: Seminario su invito del Prof. Aleksi Šedo, Dr. Sc., Dean of the First Faculty of Medicine. Title: Glycopeptides as immunological probes for the characterization of autoantibodies, biomarkers of Multiple Sclerosis

[Inv91] S42 - CoffeTalk@ISOF: Extended Edition. ISOF12- CNR Area della Ricerca di Bologna - Ed. 12; Meeting Room (1st Floor), Via P. Gobetti 101, 40129 Bologna (Italy), April 16, 2019: Seminario su invito del Dr. Paolo Dambruoso. Title: “A chemical approach to identify peptide epitopes for high affinity antibodies in autoimmune diseases”.

[Inv92] S43 – 5th Workshop of the Joint Doctoral Program in Chemistry (Università degli Studi di Trieste e Università Cà Foscari di Venezia), Room Giorgio Padoan, San Sebastiano, Venezia, June 26-28, 2019. June 28, 2019: Conferenza su invito del Coordinatore del dottorato interateneo Prof. Barbara Milani a nome del Comitato organizzatore. Title: A Chemical Reverse Approach to develop efficient and reliable peptide-based diagnostics for immune-mediated diseases

[Inv93] PL1725th Polish Peptide Symposium, Wojanów (Poland), September, 8-12, 2019. September 9, 2019: Plenary lecture su invito della Chair Prof. Justyna Brasun. Title: The Chicken or Egg dilemma: are antibodies to aberrantly modified conformational peptide epitopes in autoimmunity reminiscent of early infections?

[Inv94]  S44 - Colloquium of the Department of Bioscience and Biotechnology Konkuk University Seoul 05029 (Korea) October 14, 2019 – 3:00 pm. Title: Are antibodies to aberrantly modified conformational peptide epitopes in autoimmunity reminiscent of early infections?

[Inv95] PL18Recent Advances in Peptide Research, Joint International Peptide Symposium Korean Protein Peptide Society & SKKU College of Pharmacy. Sungkyunkwan University, Suwon (South-Korea), October 15, 2019. Title: From a synthetic N-glucosylated peptide probe to an hyper-glucosylated adhesin protein antigen:a bacterial infection triggering an antibody mediated form of Multiple Sclerosis?

[Inv96] IL28124th Korean Chemical Society National Meeting. Session: Peptides and Biological Chemistry, Changwon (South Korea), October 17-18, 2019. Invited Lecture su invito del Secretary general of the Korean Chemical Society (KCS), Division of Biological Chemistry on behalf of the Organising Committee Dr. Hyun-Suk Lim, by the President of the Korean Peptide Society Prof. Yangmee Kim e del President of the KCS Division of Biological Chemistry Prof. Sang Jeon Sung. Title: Strategies for modulation of secondary structures to optimise biological recognition.

[Inv97]  AL3 - The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel. Kick-off Meeting Rita Levi Montalcini Prize 2019, Israel-Italy Scientific Cooperation (Prof. Nir Quit, Bar-Ilan University, Dr. Mattan Hurevich, Institute of Chemistry, Hebrew University of Jerusalem, Dr. Rina Aharoni, Weizmann Institute of Sciences) December 23, 2019 – 14:00. Title: The Chicken or Egg dilemma: Are antibodies to aberrantly modified conformational peptide epitopes in autoimmunity reminiscent of early infections??

2020

[Inv98] PL1917th Iberian Peptide Meeting (17^th EPI), Auditorium of the Rocasolano Institute of Physical Chemistry (IQFR), Consejo Superior de Investigaciones Cientificas (CSIC), Madrid (Spain), February 5-7, 2020. February 5, 2020: Plenary Lecture su invito dei Chairs Rosario González-Muñiz, Mª Angeles Jiménez e María José Camarasa. Title: Strategies for modulation of peptide secondary structures to optimise biological recognition. http://epi2020.iqfr.csic.es/

[Inv99] IL29 85th Annual Meeting of the Israel Chemical Society, W1: Chemical Biology (Teddy A). International Convention Center ICC (Binyanei Hauma), Jerusalem (Israel), February 18-19, 2020. February 19, 2020 – 11:50-12:20. Invited Lecturedai Meeting Chairs Shlomo Yitzchaik and Lioz Etgar. Title: From a synthetic N-glucosylated peptide probe to an hyper-glucosylated adhesin protein antigen: a bacterial infection triggering an antibody mediated form of multiple sclerosis?

2021

[Inv100] IL30: Latest Development in Peptide Synthesis. Academic Guest Speaker. Title: The challenge to design fully automated solid-phase MW-assisted cGMP ready processes of peptide production as active pharmaceutical ingredients. Webinar 10^th March 2021 9:15am-3:00pm. https://www.cemmicrowave.co.uk/copy-of-peptide-synthesis-webinar-march-2021---speakers. https://vimeo.com/cemmicrowave/peptidewebinar2021

[Inv101] PL20: 2021 BOULDER PEPTIDE VIRTUAL SYMPOSIUM, St. Julien Hotel & Spa in Boulder, Colorado, June 11, 2021. Invited Lecture by Dr. John Philip Mayer, University of Colorado Boulder and Dr. Matthew Duffy, Title: Aberrantly modified conformational peptide epitopes, specific for antibodies biomarkers of immune-mediated diseases, can be reminiscent of an early infection. The Chicken or Egg dilemma? https://boulderpeptide.org/

INVITED LECTURES AIMED TO TECHNOLOGY TRANSFER

2004-2021

[IL1] Simposio “Direzioni future nella sclerosi multipla”, Facoltà di Medicina e Chirurgia, Università di Firenze, Dipartimento di Scienze Neurologiche e Psichiatriche, Firenze, (Italy), Aula Magna della Facoltà di Medicina. 6 Aprile 2004: Invitedspeaker by Prof. S. Sorbi. Title: CSF114(Glc): un glicopeptide sintetico, marker innovativo di sclerosi multipla mediata da autoanticorpi.

[IL2] i-techpartner Academy Italy, Research leaders and entrepreneurs assess collaborative innovation, APRE Europe, Rome (Italy). 27 November, 2007: Invited by APRE as Chief of the Scientific Committee of Toscana Biomarkers Srl (Siena) and research leader of the universities involved in funded start-ups. Title: Modified peptides as diagnostic tools for autoimmune disease: a chemical reverse approach.

[IL3] 2nd TLS Investment Advisory Panel Meeting, Hotel Garden, Via Custoza 2, Siena (Italy), Fondazione Toscana Life Sciences. July 13, 2007:Invited by Francesco Maria Senatore, Business development TLS. Title: Optimised synthetic strategies to develop an efficient diagnostic/prognostic test for Multiple Sclerosis.

[IL4] “Peptide Users Group”, Spring Symposium, Mimotopes – Genzyme Pharmaceuticals, Melbourne (Australia). October 30, 2007:Invited  by Mimotopes - The Peptide Company. Title: Optimised synthetic strategies to develop an efficient diagnostic/prognostic test for Multiple Sclerosis.

[IL5]BioInItaly 2008, Milan Chamber of Commerce Special Agency for Innovation, Affari ai Giureconsulti, Milano (Italy), March31-Apri1, 2008. April 1, 2008: Invited by the organising committee. Title: Toscana Biomarkers

[IL6] BioInItaly in partnership with innovhub, Milan Chamber of Commerce Special Agency for Innovation, Affari ai Giureconsulti, Milano (Italy), May 4-5, 2009. May 5, 2009: Invitedspeakerby Dr. Roberto Gradnik, President of Assobiotech (Italian Association for the Development of Biotechnology). Title: The Start-up Toscana Biomarkers.

[IL7] Conseil Général du Val d’Oise, 2 Avenue du Parc, 95000 Cergy-Pontoise (France), July 7, 2009: InvitedbyDr. Jean-Francois Benon, General Manager of CEEVO, (Comité d’expansion économique du Val d’Oise). Title: Molecular Detection for Life Sciences (MoDeLS). A project under the Seventh Framework Programme – Regions of Knowledge Initiative.

[IL8]Region of Osaka (Japan). Mission Economique du Val d’Oise. November 10, 2009: Invited by the Region of Osaka. Title: Molecular Detection for Life Sciences MOD&LS: A Project under the 7^th Framework Programme-Regions of Knowledge Initiative.

[IL9]State University of Osaka (Japan). November 13, 2009: Invited by the Region of Osaka. Title: Molecular Detection for Life Sciences: An European Project coordinated by the Conseil Général du Val d’Oise.

[IL10]Ricerca Impresa, Polo Scientifico di Sesto Fiorentino, Università di Firenze (Italy). December 3, 2009: Title:Molecular Detection for Life Sciences (MoDeLS): An European Project coordinated by CGVO – Ile de France.

[IL11]Conseil Régional de Bourgogne, 17, boulevard de la Trémouille CS, Dijon (France). December 9, 2009: invited by Conseil Régional de Bourgogne. Title: Molecular Detection for Life Sciences (MoDeLS): An Innovative Management Model of European Projects.

[IL12]TLS Work in Progress, Centro Ricerche Novartis, Siena (Italy). December 11, 2009: invited by the General Manager of Toscana Life Sciences Dr. G. Carganico. Title: Toscana Biomarkers S.r.l. R&D start-up company. Start-up Toscana Biomarkers.

[IL13]Presentation to Cosmetic Valley in Neuville Université (France).February 24, 2010: Invited by the Directeur Général and Founder of Cosmetic Valley Jean-Luc Ansel. Title: European Leonardo Institute of Technology@UCP. An Infrastructure to favour Innovation in Cosmetics towards Cosmeceutics.

[IL14]Hybrigenics, Paris (France). March 10, 2010: invited by the Director Industrial Operation & Technology Development Jean-Christophe Rain, Dr. Sci.Title: Post-translationally modified peptides to characterise specific biomarkers of immune-mediated diseases: a challenge for "theragnostics".

[IL15] CGVO Semaine de la Recherche et de l’Innovation Cergy-Pontoise (France).May 3, 2010: invited by the Managing Director of Val d’Oise Economic Expansion Committee Dr. Jean-Francois Benon.Title: Molecular Detection for Life Sciences. An Institute of Technology@UCP. An Infrastructure to favour Innovation in Diagnostics: an European Model.

[IL16]Roche Partnering GEM EventResearch and Technology Team. Hotel Lutetia, 45 Blvd. Raspail, 75005 Paris (France). June 23, 2010: Invited by the Manager Global Business Development Dr. Imma Barrera e dal RP DBA Leader Metabolism Dr. Andrew Sleight. Title: Toscana Biomarkers S.r.l. R&D start-up company.

[IL17]5th EU-China Business & Technology Cooperation Fair, organised by the EU Project Innovation Centre – EUPIC, and Chengdu Hi-Tech Zone Management Committee, Chengdu, Sichuan (China), 16-21 October 2010.Speech from the experts October 18, 2010: Guest speakerinvited by Segree Dai, CEO of EUPIC. Title: Molecular Diagnostics for Life Sciences (MoDeLS) An European Infrastructure based on a Technology Platform Network to favour R&D in SMEs

[IL18] China – Italy Regional Cooperation Forum on Technology and Innovation, Fortezza da Basso, Firenze (Italy), 10-12 November 2010. November 11, 2010: invitedspeaker for the session “Life Sciences e industria della salute” by Assobiotec and Toscana Life Sciences as a successful example of SME. Title: Toscana Biomarkers: the proof-of-concept of an innovative approach to molecular diagnostics.

[IL19]F. Hoffman La Roche, Basel (Switzerland). February 1, 2011: invited by the Director of Peptide Discovery. Title: Toscana Biomarkers S.r.l. R&D start-up company.

[IL20] Meeting UCP & 3M Science, Neuville Université. September 1, 2011: invitedspeaker by 3M Science.Title: Molecular Diagnostics for Life Sciences (MoDeLS). An European Infrastructure based on a Technology Platform Network to favour R&D in SMEs.

[IL21] IPSEN INNOVATION – ZI de Courtaboeuf 5, Av. Du Canada 91940 Les Ulis (France). January 18, 2012: Invited by Dr. Christophe Lanco, Sr Scientist - Compounds Discovery. Title: The importance of a “Chemical Reverse Approach” to modulate peptide secondary structures inducing specific and high affinity biological recognition.

[IL22] EuroPEPTIDES 2013, Clarion Congress Hotel Prague (Czech Republic), November 13-14, 2013. November 13, 2013: Invited as speaker at the forefront of peptide development for the “Session on peptide diagnostics and biomarkers” by the Chair Dr. Waleed Danho on behalf di INFORMA. Title: Optimised Synthetic Strategies to Post-Translationally Modified Peptides as Reliable Diagnostics of Immune-Mediated Diseases.

[IL23]Connexions R&D 2013: Rencontrez les acteurs de la recherche en cosmétique. Les Turbulences, Frac Centre, Orléans (France). December 10, 2013: Invited by the President J.-L. Ansel on behalf of the scientific committee of Cosmetic Valley France. Title: Peptides et applications cosmétiques.

[IL24]1ère Edition des rencontres interdisciplinaires «Chimie-Biologie». SATT idfinnov, Cité Internationale Universitaire – Maison de Norvège, Paris (France). March 18, 2014: Invited by the scientific Committee of idfinnov. Title: « Projet PepKit » Mise en place et développement d’une approche de « chimie inverse » à l’Université de Cergy-Pontoise et création de la plateforme PeptLab@UCP ».

[IL25] Conférence Inter-professionnelle SUP’BIOTECH.Dermo-Cosmétologie : les enjeux de la R&D, Paris (France). February 10, 2015 : invited speaker by the scientific Committee. Title: Peptides et applications cosmétiques avec la présentation des plateformes de recherche sur les peptides (Université de Cergy-Pontoise).

[IL26] Peptide Therapeutics Forum, BASEL LIFE, Congress Centre Basel (Switzerland), September, 10-11, 2019. September 11, 2019: Invited lecture by the Chairs Dr. Thomas Vorherr (Novartis Pharma AG, Basel, CH) e Roderich Suessmuth (Technical University of Berlin, Germany). Title: Exotic side chain-to-side-chain cyclization modes in octreotide analogs for tumor pretargeting. https://www.basellife.org/2019/basel-life-structure/innovation-forums/scientific-programme/peptide-therapeutics.html

[IL27] IOPC 2019 - International Oligonucleotides and Peptides Conference, Ramada Plaza Hotel, Milano (Italy), September 17-18, 2019. September 18, 2019: Invited by TeknoScienze as Member of the Scientific Committee, Chair of the Workshop on Delivery and Speaker. Title: Specific Glycosylation Techniques for Efficient Protein Therapeutics. https://www.iopc-tks.com/committee/

[IL28] UniFi@ARTES 4.0: tecnologie e servizi per le imprese: quali sono e come accedere alle competenze dell’unità operativa ARTES 4.0 dell’Università degli Studi di Firenze. Firenze (Italy) 22-23 Giugno 2021. Invited by University of Florence. Title: I peptidi: una lezione dalla natura per sviluppare molecole sostenibili d’interesse dell’industria cosmeceutica, nutraceutica, diagnostica, farmaceutica, dei materiali e molto altro.

Chair of scientific sessions

Monday September 1, 2008 (16:00-17:20):  Chair of the Session 04 “Libraries and peptidomimetic applications”, 30th European Peptide Symposium, Helsinki (Finland), invited by the Chair Dr. H. Lankinen.

Wednesday October 28, 2009 (9:00-13:15): Chair of the Session III, Barcelona BioMed Confreences. Peptide engineering: therapeutic peptides, Barcelona (Spain), invited by the Chairs Prof. E. Giralt and Prof. C. Toniolo.

Monday September 6, 2010 (10:40-12:30):  Chair of the Session S2 “Synthetic Chemistry of amino acids and peptides”, 31st European Peptide Symposium, Copenhagen, invited by the Chair Prof. M. Meldal.

Thursday July 29, 2010 (15:20-16:20): Chair of the Session B, 24th International Symposium on the Organic Chemistry of Sulfur – ISOCS-24, Florence (Italy), invited by the Chair Prof. A. Degl’Innocenti.

Sunday June 10, 2012 (9:00-11:00): Chair of the Session VIII “Peptide drug design”, 13th Naples Workshop on Bioactive Peptides, Napoli (Italy), invited by the Chair Prof. G. Morelli.

Thursday September 6, 2012 (11:00-12:30): Chair of the 16th Session, 32th European Peptide Symposium, Athens (Greece), invited by the Chair Prof. G. Kokotos.

Wednesday September 4, 2013 (15:00-16:55): Chair of the Sessione “Enzymes substrates and inhibitors II”, 22nd Polish Peptide Symposium, Kudowa Zdroj (Poland), invited by the Chair Prof. R. Latajka.

Friday June 13, 2014 (16:40-18:20): Chair of the Session IB “Antimicrobial Peptides”, 14th Naples Workshop on Bioactive Peptides, Napoli (Italy), invited by the Chair Prof. G. Morelli.

Monday September 1, 2014 (14:00-16:40): Chair of the Session 3, 33rd European Peptide Symposium, Sofia (Bulgaria), invited by the Chair Prof. L. Vezenkov.

Wednesday September2, 2015 (9:00-10:40): Chair of the Session “Peptides/Peptidomimetics for Medicine II”, 23rd Polish Peptide Symposium, Spala 2015 (Poland), invited by the Chair Prof. B. Kolesinska.

Sabato 3 Ottobre 2015 (8:30-13:30): Moderatore della I sessione “Chimica, cibo, acqua potabile e sicurezza alimentare”, XVII Congresso Nazionale dei Chimici, Milano (Italy), invitata dal Coordinatore scinetifico Dr. E. Miriani.

Thursday September 8, 2016 (8:30-10:30): Chair of the Session “Imaging and modulation of enzymes and receptors: Receptor Modulation”, 34th European Peptide Symposium-8th International Peptide Symposium, Leipzig (Germany), invited by the Chair Prof. A. Beck-Sickinger.

Friday December 7, 2018 (14:50-16:20): Chair of the Session 14 “Peptides Today and the Future”, 10th International Peptide Symposium, Kyoto (Japan), invited by the Chair Prof. Prof. S. Futaki.

Oral AND Poster COMMUNICATIONS SELECTED FOR PRESENTATIONS AT NATIONAL AND INTERNATIONAL SYMPOSIA

Oral Communications

(Underlined the name of the lecturer)

1985-2021

1985-1991

[OC1] A.M. Papini, G. Dupuis. Anti-hapten monoclonal antibodies: attempts to produce anti- urushiol monoclonal antibodies in Balb/c mice. 6th Meeting GIRDCA, Torino (Italy), November 16, 1985.

[OC2] L. Moroder, K. Köcher, A.M. Papini, M. Dufresne and C.H. Schneider. The mode of peptide-antigen presentation critically affects the specificity of both immune response and antigen-antibody recognition. 8th Symposium on Chemistry of Peptides and Proteins FRG-USSR, Aachen (Germany), September 29-October 3, 1991, L-49.

1996-2000

[OC3] A.M. Papini, S. Mazzucco, A. Franchi, M. Chelli, M. Ginanneschi, G. Rapi, R. Tosi, G. Greco, D. Fruci, R. Butler, L. Massacesi. Characterization of the T cell response to lipid bound and lipid free human myelin peptides in multiple sclerosis. Progress Report, First Project on Multiple Sclerosis, Istituto Superiore di Sanità, Roma (Italy), November 28-29, 1996, Reports ISTISAN, 96/32, 57-58.

[OC4] A.M. Papini, M. Biondi, D. Pinzani, S. Mazzucco, M. Chelli, M. Ginanneschi, G. Rapi, B. Mazzanti, M. Vergelli, L. Massacesi, L. Amaducci. Lipoderivatives of an immunodominant epitope of myelin basic protein increased T cell responsiveness in Lewis rats. 15th American Peptide Symposium, Nashville (Tennessee, U.S.A.), June 14-19, 1997, Abstract L093, p. 2-47.

[OC5] A.M. Papini, S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, G. Rapi.

Fmoc-2-aminopalmitic acid for the synthesis of lipopeptides with an hydrophobic chain on a C-C bond. 15th American Peptide Symposium, Nashville (Tennessee, U.S.A.), June 14-19, 1997, (Mini Symposium) Abstract MS30, p. 2-67.

[OC6] S. Mazzucco, E. Nardi, M. Chelli, A.M. Papini, M. Vergelli, B. Mazzanti, L.Massacesi. Labeled lipopeptides of myelin basic protein for the study of the molecular mechanism of multiple sclerosis. Forum Jeunes Chercheurs, Journée d’étude en chimie organique et chimie des materiaux, Université de Cergy-Pontoise (Neuville sur Oise), 25 Juin 1998, (Lecture) Abstract p. 20.

[OC7] A.M. Papini, R. Fioresi, S. Mazzucco, S. Matà, F. Lolli, M. Vergelli, M. Chelli, M. Ginanneschi, G. Rapi, B. Mazzanti, L. Massacesi, F. Pinto. Glycopeptides of hMOG(30-50) detect antibody response in multiple sclerosis and other neurological diseases. 25th European Peptide Symposium, Budapest (Hungary), August 30-September 4, 1998 (Lecture) Abstract L22, p. 91; J. Peptide Sci. (1998), 4, ix.

[OC8]F. Meyer, A. Laaziri, J. Uziel, A.M. Papini, S. Jugé. Nouvelle voie d’acces aux a-aminoesters b-halogénés ou phosphorés a partir d’oxazolines dérivées de la L-Sérine. Journées de Chimie Organique. Ecole Polytechnique -Palaiseau (France), 15-17 Septembre 1998.

[OC9] A.M. Papini, R. Fioresi, S. Mazzucco, E. Nardi, S. Matà, F. Lolli, M. Vergelli, M. Chelli, M. Ginanneschi, B. Mazzanti, L.Massacesi, F. Pinto. Asn³¹[N-Glucosyl]hMOG(30-50): a useful antigen to identify anti-MOG antibodies in multiple sclerosis patients. 10^th International Congress of Immunology, New Delhi (India), November 1-6, 1998, Interactive Workshop on Neuroimmunology and autoimmune disorders of CNS W-28.

[OC10] L. Massacesi, B. Mazzanti, M. Vergelli, A.M. Papini, S. Mazzucco, M. Chelli, R. Tosi, R. Butler, G. Greco, D. Fruci. Caratterizzazione della risposta linfocitaria verso peptidi e lipopeptidi della mielina umana nella sclerosi multipla. Progress Report, Second research project on Multiple sclerosis, Istituto Superiore di Sanità, Roma (Italy), (1998), Rapporti ISTISAN, 98/7, 75-76.

[OC11] F. Lolli, V. Zipoli, S. Matà, F. Pinto, L. Massacesi, E. Nardi, S. Mazzucco, M. Chelli, A.M. Papini, M. Vergelli. Intratechal synthesis of autoantibodies to a glycoderivative peptide of MOG in multiple sclerosis. X° National A.I.N.I. Congress, Associazione Italiana Neuroimmunologia, Florence (Italy), Novembre 15-16, 1999; Abstract A62, J. Neuroim. (1999) 31-33.

[OC12] L. Massacesi, B. Mazzanti, M. Vergelli, A.M. Papini, S. Mazzucco, M. Chelli, R. Tosi, R. Butler, G. Greco, D. Fruci. Characterization of lymphocyte response to human myelin peptides and lipopeptides in multiple sclerosis. Second research project on Multiple sclerosis. Second year. Istituto Superiore di Sanità, Roma (Italy), (1999), Rapporti ISTISAN, 99/18, 85-88.

[OC13] F.Meyer, H.Laaziri, J.Uziel, A.M.Papini, S.Jugé. Nouvelle voie d’accès aux acides a-aminés b-halogénés ou b-phosphorés à partir d’oxazolines dérivées de la sérine. Semaines d’Etude en Chimie Organique, SECO XXXVII, Houffalize (Belgique), 21-26 May, 2000.

[OC14] A.M. Papini,E. Nardi, B. Mazzanti, T. Biagioli, E. Traggiai,M. Chelli, M. Ginanneschi, H. Kalbacher, L. Massacesi, M. Vergelli. Effect of lipoconjugation on MBP peptide epitopes for CD4+ T cell responsiveness. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, Abstract OC18, J. Pept. Sci., Supplement to Vol. 6, 2000, S 63.

[OC15] E. Nardi, S. Matà, V. Zipoli, E. Mastrangelo, M. Chelli, A.M. Papini, M. Vergelli, F. Lolli. Ruolo del residuo glicosilico nel riconoscimento di autoanticorpi contro peptidi glicosilati della MOG. XI Congresso AINI (Associazione Italiana di Neuroimmunologia), Camogli (Italy), October 26-28, 2000, Abstract C38.

2002

[OC16] A. M. Papini, B. Mulinacci, E. Peroni, G. Sabatino, S. Matà, M. Chelli, A. Carotenuto, P. Rovero, F. Pinto, F. Lolli. A glycopeptide detecting autoantibodies in multiple sclerosis: from a diagnostic test toward a selective therapeutic strategy. 27th European Peptide Symposium, Sorrento (Italy), August 31st-September 6th, 2002, J. Pept. Sci., 2002, 8(Suppl.), S70, Abstract L55.

[OC17] A.M. Papini, F. Nuti, E. Nardi, E. Peroni, M. Chelli, B. Mazzanti, F. Lolli, J. Uziel, A. Brandi. Sintesi di lipoamminoacidi eniantiomericamente puri per l’ottenimento di lipopeptidi come vaccini sintetici per la sclerosi multipla. XXVIII Convegno Nazionale della Divisione di Chimica Organica della S.C.I., Rome (Italie) 16-20 Septembre 2002, Abstract O16.

[OC18] A.M. Papini, F. Nuti, E. Peroni, M. Chelli, B. Mazzanti, T. Biagioli, F. Lolli, A. Brandi. Lipopeptide as synthetic vaccines in Multiple Sclerosis animal model: stereoselective synthesis of lipoaminoacids. Third Italian-French Meeting on Organic Chemistry. “Organic Chemistry towards Interfaces”, Pise (Italie), 20-23 Novembre, 2002, Abstract OC10.

2003

[OC19] A.M. Papini. MS PepKit: the prototipe of the first test, based on the glycopeptide CSF114(Glc), to follow-up the disease activity in multiple sclerosis. XXI Congresso Nazionale della Società Chimica Italiana, Divisione di Chimica dei Sistemi Biologici, Torino (Italy), 22-27 Giugno, 2003. Abstract SB-CO-015.

[OC20] E. Peroni, F. Lolli, B. Mazzanti, M. Pazzagli, B. Bonetti, L. Massacesi, M. Chelli, P. Rovero, A.M. Papini. Towards a therapeutic apheresis in Multiple Sclerosis based on a glycopeptide antigen able to isolate specific autoantibodies. 18th American Peptide Symposium, Boston, MA, USA, 19-23 Juillet, 2003, LY 1, Abstracts p. 277. Selected for the Young Investigators’ Mini-Symposium.

[OC21] A.M. Papini, B. Mulinacci, E. Peroni, F. Nuti, G. Sabatino, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, L. Massacesi, M. Chelli, P. Rovero, and F. Lolli. MS PepKit:the first diagnostic test based on CSF114(Glc), a glycopeptide to follow-up Multiple Sclerosis. 18th American Peptide Symposium, Boston, MA, USA, 19-23 Juillet, 2003, O62, Abstracts p. 298.

2004

[OC22] I. Paolini, F. Nuti, B. Mulinacci, E. Peroni, M.C. Alcaro, G. Sabatino, B. Mazzanti, M. Chelli, A. Brandi, F. Lolli, P. Rovero, A.M. Papini. Glicopeptidi per la diagnosi e la terapia della sclerosi multipla. Riunione Scientifica Annuale della Società Chimica Italiana Organica, Sezione Toscana, 17 Décembre, 2004.

2005

[OC23] B. Mulinacci, C. Breithaupt, P.P. Pal, N. Budisa, M. Pazzagli, B. Mazzanti, P. Rovero, L. Moroder, A.M. Papini. Cross-reactivity studies of rMOG_ED with the synthetic putative autoantigen CSF114(Glc) and [N³¹(Glc)]hMOG(30-50) in Multiple Sclerosis patients’ sera. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 Juin, 2005. Bert Schram Price for Young Investigators. LY 03, Abstract p. 484.

[OC24] A.M. Papini, M.C. Alcaro, E. Peroni, B. Mulinacci, A. Carotenuto, G. Sabatino, B. Mazzanti, M. Pazzagli, M.C. Pozo-Carrero, F. Nuti, L. Battistini, M. Chelli, F. Lolli, P. Rovero. A combinatorial approach to optimise a prognostic test to follow-up Multiple Sclerosis disease activity. EUROCOMBI3, Winchester, U.K., 18-21 Juillet, 2005, Abstract p. 34.

[OC25] F. Lolli, M. Chelli, P. Rovero, A.M. Papini. An aberrant N-glucosylation triggering autoimmunity in Multiple Sclerosis. XVIII International Symposium on Glycoconjugates, Glyco XVIII, 4-9 Septembre, 2005, Florence, Italie. L160, Glycoconjugate J., 2005, 22(4–6), 220.

[OC26] B. Kolesinska, Z. Kaminski, A.M. Papini. New generation of Triazine-based Coupling Reagents. 18th Polish Peptide Symposium, Wroclaw, Pologne, 4-8 Septembre, 2005, Abstract L-18.

[OC27] F. Lolli, M. Chelli, P. Rovero, A.M. Papini. Role of glycosylation in autoimmune diseases. Mini-Symposium “Multidisciplinary approaches to dissect the molecular mechanisms of diseases”, First European Conference on Chemistry for Life Sciences, Rimini, Italie, 4-8 Octobre, 2005, Lecture, Abstract p. 73.

2006

[OC28] A.M. Papini. An aberrant glucosylation of myelin proteins triggering autoimmunity in Multiple Scleorsis. Chemistry & Biology of Peptides, Gordon Research Conference, February 19-24, 2006 Ventura Beach Marriott, CA, USA.

[OC29] N. Alexandris, M.C. Alcaro, A.M. Papini, R. Bianchini. Design and synthesis of heme peptides & bioremediation. 7th . Conference Medicinal Chemistry: Drug Discovery and Design. Conference and Cultural Center, University of Patras, Patras (Greece). March 8-11, 2006. Abstract L42 pag. 64.

[OC30] A.M. Papini, A. Carotenuto, M.C. Alcaro, B. Mulinacci, E. Peroni, G. Sabatino, F. Nuti, I. Paolini, M. Chelli, F. Lolli, and P. Rovero. From aberrant post translational modifications of myelin proteins to synthetic antigen probes detecting biomarkers of autoimmune diseases. Promelab, 1^st International Workshop on Expression, Function & Structure of Membrane Proteins. 18-22 June 2006, Firenze, Italy.

[OC31] A.M. Papini, M. C. Alcaro, B. Mulinacci, E. Peroni, G. Sabatino, F. Nuti, I. Paolini, M. Chelli, F. Lolli and P. Rovero. From aberrant post translational modifications of proteins to synthetic antigenic probes detecting biomarkers of autoimmune diseases. 1^st European Chemistry Congress, 27-31 August 2006, Budapest, Hungary. Abstract J-OC-5, pag. 222.

[OC32] B. Kolesinska, G. Sabatino, M. Chelli, P. Rovero, J. Kolesinska, K.G. Jastrzabek, Z.J. Kaminski, A.M. Papini. A new generation of N-triazinylammonium coupling reagents versatile for peptide synthesis by different strategies. 29^th European peptide Symposium, Gdansk, Poland, September 3-8, 2006, Abstract L009.

[OC33]G. Sabatino, B. Kolesinska, M. Chelli, J. Kolesinska, P. Rovero, Z. Kaminski, A.M. Papini. A new generation of N-triazinylammonium coupling reagents versatile for peptide synthesis by different strategies. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, 10-15 Settembre 2006. Abstract ORG-F-17 (Flash Communication presentata dall’assegnista di ricerca G. Sabatino).

[OC34]M.C. Alcaro, A. Carotenuto, A.M. D’Usi, C. Bonaccini, F. Barbetti, F. Lolli, M.Chelli, A. Tramontano, E. Novellino, A.M. Papini, P. Rovero. Conformationally Driver Rational Design of Glycopeptides as Synthetic Probes for the Detection of Autoantibodies, Biomarkers of Multiple Sclerosis. XXII Congresso Nazionale della Società Chimica Italiana, Firenze, 10-15 Settembre 2006. Abstract GCP-O-06 (Comunicazione orale presentata dall’assegnista di ricerca M.C. Alcaro).

2007

[OC35] A.M. Papini. An innovative “chemical reverse approach” for autoimmune diseases diagnosis: a consistent strategy to include aberrant post-translational modifications. 4th International Peptide Symposium, 7° Australian Peptide Symposium & 2nd Asian Pacific International Peptide Symposium, Cairns, QLA, Australia, October 21-25, 2007. Abstract 26.

[OC36] Le Chevalier Isaad, M. Scrima, S. Cantel, J. Levy, P. Rovero, A.M. D'Ursi, M. Chorev, A.M. Papini (2008). Synthesis and conformational analysis of a series of cyclic i-to-i+4 side chain-to-side chain 1,4-disubstituted [1,2,3]triazolyl-bridged PTHrP(11-19) derivatives. 30^th European Peptide Symposium, 31 August-5 September 2008, Helsinki, Finland. Abstract Y04. JOURNAL OF PEPTIDE SCIENCE (2008), vol. 14(8S), p. 3, ISSN: 1075-2617, doi: 10.1002/psc.1073. Selected for the Dr Bert L. Schram Young investigator’s minisymposium Part 1.

2010

[OC37]C. Testa, S. Carganico, F. Nuti, M. Scrima, A. M. D’Ursi, M. L. Dirain, N. Lubin Germain,  C. H. Luevano, M. Chorev,  P. Rovero, A.M. Papini. Stabilization of b-turn conformation in melanocortin like peptide by click side chain-to-side chain cyclization. 31stEuropean Peptide Symposium, 31st EPS, Copenhagen (Denmark), 5-9 September 2010. Oral O8

[OC38] S. Pandey, E. Peroni, MC Alcaro, F. Rizzolo, F. Nuti, M. Chelli, S Matà, P. Rovero, F. Lolli, AM. Papini. Mimicry effect of the neo-epitope [Asn641(Glc)]FAN(635-655) with CSF114(Glc) detecting autoantibodies in Multiple Sclerosis, 31^th European Peptide Symposium, Copenhagen (Denmark), 5-9 September 2010. Abstract O1

2012

[OC39] C. Rentier, A.M. Papini. Aberrant post-translationally modified peptides for diagnostics and monitoring of autoimmune diseases3rd Ph.D. Day, Florence (Italy), May 16, 2012.

[OC40] C. Rentier, O. Monasson, F. Nuti, E. Peroni, G. Pacini, G. Rossi, M. Larregola, P. Rovero, A.M. Papini. Synthesis of post-translationnally modified peptides as molecular probes for immune-mediated diseases: the case of Primary Biliary Cirrhosis. 18th Congress of GFPP, May 28th, 2012 Le Lazaret, Sète (France). Abstract O11, pag. 43.

2014

[OC41] C. Rentier, G. Pacini, F. Nuti, C. Selmi, P.M. Battezzati, P. Rovero, A.M. Papini Peptides of the dihydrolipoyl acetyltransferase for the detection of autoantibodies in autoimmune diseases. 14th Naples Workshop on Bioactive Peptides “The Renaissance Era of Peptides in Drug Discovery”, Naples (Italy), June 12-14 2014.

[OC42] C. Rentier, G. Pacini, F. Nuti, C. Selmi, P.M. Battezzati, P. Rovero, A.M. Papini. Peptides of the dihydrolipoamide acetyltransferase for the detection of autoantibodies in autoimmune diseases. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Oral. Abstract YO08 – p. 37.

[OC43] M. Larregola, N. Auberger, M. Di Pisa, E. Peroni, G. Chassaing, S. Lavielle, O. Lequin, J.M. Mallet, A.M. Papini. A CONFORMATIONAL STUDY OF NEW GLASER-CYCLIZED PEPTIDES. 33rd European Peptide Symposium, National Palace of Culture, Sofia (Bulgaria), 31 August-5 September 2014. Oral. Abstract O45, p 66.

[OC44] S. Pascarella, F. Melani, L. Giovannelli, A.M. Papini, P. Rovero. Mimicking Serine Protease Inhibitor H1 Chaperone Function in Collagen Biosytnhetic Pathway via the Template Assembled Synthetic Protein Approach. Peptides in Paris – PIPS 2014, Gennevilliers site of the University of Cergy-Pontoise, Institute of Advanced Studies. October 5-8, 2014. Abstract YIO10, p. 40.

2015

[OC45] A.M. Papini, M. Larregola. Peptide stability and formulation. Proteinov. Colloque Adebiotech. Biocitech, Cité des entreprises de santé et de Biotechnologies, Romainville (France). 23-24 September 2015.

[OC46] Rentier C, Pacini, G.; A. Carotenuto, Nuti, F.;Selmi,C.; P.M. Battezzati, Rovero, P.; Papini, A.M. Peptides of the dihydrolipoyl acetyltransferase for the detection of autoantibodies in primary biliary cirrhosis. 52^nd Japanese Peptide Symposium, Hiratsuka Japan, November 16-18, 2015 Abstract Y-13 (Best Oral Young Investigator Oral).

2016

[OC47] C. Testa, M.T.C. Walvoort, R. Eilam, R. Aharoni, F. Nuti, G. Rossi, F. Real-Fernandez, R. Lanzillo, V. Brescia Morra, F. Lolli, P. Rovero, B. Imperiali, A.M. Papini. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus influenza. Cortona Procarioti, Cortona (Italia) 12-14 Maggio 2016. Oral O28.

[OC48] C. Testa, M.T.C. Walvoort, R. Eilam, R. Aharoni, F. Nuti, G. Rossi, F. Real-Fernandez, R. Lanzillo, V. Brescia Morra, F. Lolli, P. Rovero, B. Imperiali, A.M. Papini. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus influenza. 15^th Naples Workshop on Bioactive Peptides, Napoli (Italia) 23-25 Giugno 2016. Oral O4.

[OC49] C. Testa, M.T.C. Walvoort, R. Eilam, R. Aharoni, F. Nuti, G. Rossi, F. Real-Fernandez, R. Lanzillo, V. Brescia Morra, F. Lolli, P. Rovero, B. Imperiali, A.M. Papini. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of nontypeable Haemophilus influenza. 34^th European Peptide Symposium and the 8^th International Peptide Symposium, Leipzig (Germany), 4 – 9 Settembre 2016.

[OC50] L. Altamore, G. Sabatino, F. Real-Fernandez, G. Rossi, A. Lapolla, P. Rovero, A.M. Papini. Peptidi dell'enterovirus Coxsackie: studio della cross-reattività con anticorpi anti-hGAD nel diabete di tipo 1. Prima Giornata Scientifica della Società Italiana Peptidi (ItPS), Napoli (Italia) 22 Giugno 2016. Oral.

2018

[OC51] B. Dalla Volta, G. Sabatino, A. Grammatikopoulos, M. Vignoli, A.M. Papini, G. Pappalardo, P. Rovero, A. Kapurniotu. Conformationally constrained analogues of amyloidogenic segments of Islet Amyloid Polypeptide. II National Conference of Italian Peptide Society, AulaMagna Partenope – Centro Congressi “Federico II”, June 5-6, 2018. O2

[OC52] A. Mazzoleni, C. Testa, S. Francesconi, S. Lavielle, P. Rovero, J.-M. Mallet, and A.M. Papini. Synthesis and characterisation of glucosylated peptides: toward selective plasmapheresis-based treatment of Multiple Sclerosis. II National Conference of Italian Peptide Society, AulaMagna Partenope – Centro Congressi “Federico II”, June 5-6, 2018. O16

[OC53] L. Altamore, C. Testa, F. Real-Fernandez, G. Sabatino, A. Lapolla, C. Selmi, F. Borri, M. Przybylski, J. Hayek, P. Rovero, and A.M. Papini. Use of peptide mimetics of proteins to characterise immune resposne in different pathologies: a powerful approach. II National Conference of Italian Peptide Society, AulaMagna Partenope – Centro Congressi “Federico II”, June 5-6, 2018. O16.

[OC54] C. Bello, A.M. Papini, and C.W. W. Becker. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. 16^th Naples Workshop on Bioactive Peptides, Napoli (Italia) June 7-9, 2018. Oral O27.

[OC55] C. Bello, A.M. Papini, C.F. W. Becker. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. 19th Tetrahedron Symposium, Riva del Garda-Fierecongressi S.p.A., Parco Lido, Riva del Garda (Italy), 26-29 June 2018.

[OC56] C. Bello, A.M. Papini, and C.W.W. Becker. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. 35th European Peptide Symposium, University College Dublin (Ireland) August 26-31, 2018. Oral OP7. Journal of Peptide Science (2018), Vol 24(S2) p: 50. Meeting Abstract: OP7. Publisher WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA   Published: SEP 2018

[OC57] A.M. Papini, P. Rovero, F. Lolli, R. Lanzillo, C. Testa, B. Imperiali, M. Walwoort, R. Eylam, R. Aharoni, F. Nuti, V. Brescia Morra. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenza. 10th International Peptide Symposium, Kyoto (Japan) December 3-7, 2018. Oral 088.

2019

[OC58] P. Rovero, A.M. Papini. The Industry-University Joint Laboratory for the Synthesis of Peptides of Pharmaceutical Interest (PeptFarm):  a new efficient tool for technology transfer at the University of Florence. International Symposium “Chemistry meets industry and society: a creative showcase conference”, Workshop 3: “Smart Peptide Chemistry for Next Generation Industry in a Sustainable Society”, Grand Hotel Salerno, Lungomare Clemente Tafuri, 1, Salerno (Italy), 28-30 Agosto 2019. Abstract WS3 XY00. Oral Presentation.

[OC59] A. Mazzoleni, C. Testa, F. Real-Fernandez, P. Rovero, J.-M. Mallet, A.M. Papini. N-glucosylated adhesin peptide-dendrimers: toward a selective apheresis for personalized treatment of multiple sclerosis. 25th Polish Peptide Symposium, Wojanów (Poland), September 8-12, 2019. Oral Communication L30 (pag. 51).

[OC60] M. Kijewska, F. Nuti, M. Wierzbicka, M. Waliczek, P. Ledwoń, A. Staśkiewicz, T. Koch, F. Real-Fernandez, G. Sabatino, P. Rovero, P. Stefanowicz, Z. Szewczuk, A.M. Papini. The novel Boronic-ChemMatrix Resin to selectively fish out deoxyfructosylated peptides. 25th Polish Peptide Symposium, Wojanów (Poland), September 8-12, 2019. Oral Communication L27 (pag. 48)

2020

[OC61] A. Staśkiewicz, L. Macchia, F. Nuti, M. Jewgiński, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Design and synthesis of clicked oxytocin analogs, IV Doctoral Forum Jan Kochanowski University, Kielce, Poland. 17-19 November 2020 (online). Oral Communication

[OC62] P. Ledwoń, C. Bello, A.M. Papini, P. Rovero, R. Latajka. Design, synthesis and biological investigation of new peptides and peptidomimetics preventing skin damage. IV Doctoral Forum Jan Kochanowski University, Kielce, Poland. 17-19 November 2020 (online). Oral Communication

[OC63] L. Pacini, G. Sabatino, A. D’Ercole, M. Zini, A. Ribecai, A. Paio, P. Rovero, A.M. Papini. An optimized scalable fully automated solid-phase microwave-assisted cGMP-ready process for the preparation of Eptifibatide. III Meeting of the Italian Peptide Society, Rome, Università La Sapienza, December 12, 2020. O15

[OC64] A. D'Ercole, G. Sabatino, L. Pacini, I. Capecchi, A.M. Papini, P. Rovero. Microwave-assisted copper-catalysed azide-alkyne cycloaddition on solid support. An affective and easy method to develop a new generation of “stapled” H1-Relaxin B single-chain peptides. III Meeting of the Italian Peptide Society, Rome, Università La Sapienza, December 12, 2020. O16

[OC65] F. Errante, L. Pacini, F. Real Fernandez, I.A. Vitale, A.M. Papini, P. Rovero. Design and synthesis of SARS-CoV-2 antigens for diagnostics and vaccinology. III Meeting of the Italian Peptide Society, Rome, Università La Sapienza, December 12, 2020. O28

[OC66] A. D'Ercole, G. Sabatino, L. Pacini, I. Capecchi, A.M. Papini, P. Rovero. On resin microwave-assisted copper-catalysed azide-alkyne cycloaddition to stabilize new generation of H1-Relaxin B single chain “stapled” analogues. Life Science Tuesday #6 Chemical Biology. Webinar Austrian Association of Molecular Life Sciences and Biotechnology, Vienna (Austria). December 15, 2020. Science Fash Video SF-04.

Poster Communications

(underlined the name of the reseracher who presented the poster)

1986-1990

[P1] A.M. Papini, M. Ginanneschi, G. Rapi, M. Chelli. Sintesi e struttura di addotti aptene-dipeptide: possibili agenti desensibilizzanti nelle dermatiti da contatto. 32° Congresso Nazionale della Società Italiana di Biochimica, Giardini Naxos, Messina (Italy), September 28-October 1, 1986, P-12.

[P2] M. Ginanneschi, G. Rapi, M. Chelli, A.M. Papini. Sintesi di 17-spiro-5’-ossazolidin-2’,4’-dioni steroidi. Convegno Nazionale organizzato dalla Società Chimica Italiana, Divisione Chimica Organica: Giornate di Chimica delle Sostanze Naturali, Maratea (Italy), May 28-31, 1989, P-28.

[P3] A.M. Papini, M. Chelli, M. Ginanneschi, G. Rapi, G. Dupuis. Studies on the mechanism of suppression of the skin response to alantolactone: conformational characterization of the adduct H- Cys(S-alantolactone)-Ala-OMe. Second Naples Workshop on Bioactive Peptides, organizzato dall’Università di Napoli Federico II, Capri (Italy), May 21-23, 1990, C-28, pag. 87.

1991-2000

[P4] A.M. Papini, M. Chelli, M. Ginanneschi, G. Rapi, E. Borghi, M. Occhiuzzi, F. Laschi, P. Rovero. Synthesis and physico-chemical studies of metal ion binding properties of histidyl-glycyl peptides as model compounds. Twelfth American Peptide Symposium; Massachusetts Institute of Technology, Cambridge, (Massachusetts, USA), June 16-21, 1991, P-158.

[P5] L. Moroder, S. Rudolph, A.M. Papini. Intramolecular alkylation of histidine in maleoyl-peptides. Twelfth American Peptide Symposium; Massachusetts Institute of Technology, Cambridge, (Massachusetts, USA), June 16-21, 1991, P-416.

[P6] E. Borghi, M. Chelli, M. Ginanneschi, F. Laschi, A.M. Papini, G. Rapi, P. Rovero. Studies on the interaction of linear histidyl-glycyl peptides with metal ions. 36° Congresso Nazionale della Società Italiana di Biochimica, organizzato dall’Università di Ferrara, Ferrara (Italy), September 10-13, 1991, p.14. Italian Biochemical Society Transactions (IBST) Mini-paper, (1991), 2, 14.

[P7] M. Chelli, E. Borghi, M. Ginanneschi, F. Laschi, M. Occhiuzzi, A.M. Papini, D. Pinzani, G. Rapi. Interaction of Me2+ ion with linear L-histidyl-glycyl tetrapeptides by magnetic resonance techniques. 3rd Naples Workshop on Bioactive Peptides, organizzato dall’Università di Napoli Federico II, Capri (Italy), May 24-27, 1992, M-13, pp. 98-99.

[P8] M. Chelli, M. Ginanneschi, A.M. Papini, G. Rapi. Side-reactions in liquid phase peptide synthesis: cyclization of histidine azide at room temperature. 22nd European Peptide Sympiosium, Interlaken (Switzerland), September 13-19, 1992, P-46.

[P9] L. Quartara, C.A. Maggi, P. Rovero, M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi. Neurokinin A (NKA) antagonists: studies on conformation-activity relationship of linear and cyclic heptapeptides. 22nd European Peptide Sympiosium, Interlaken (Switzerland), September 13-19, 1992, P-225.

[P10] M. Chelli, M. Ginanneschi, C.A. Maggi, A.M. Papini, R. Patacchini, D. Pinzani, L. Quartara, G. Rapi. Synthesis and biological activity of tachykinin analogues containing hydrophobic moieties. Proteine 93, VII Convegno Nazionale, Parma (Italy), May, 26-28, 1993, E-63, p. 151.

[P11] M. Chelli, M. Ginanneschi, C.A. Maggi, A.M. Papini, D. Pinzani, L. Quartara, G. Rapi. Pfp of adamantane acetic acid in the synthesis of tachykinin analogues containing hydrophobic moieties. 13th American Peptide Symposium, Edmonton (Alberta, Canada), June 20-25, 1993, P-413, p. 2-104.

[P12] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi, P. Rovero, E. Borghi, M. Occhiuzzi, F. Laschi. The new model-peptide cyclo(L-His-Gly)4: comparative syntheses and magnetic resonance investigations on the interaction with divalent metal ions. II Convegno nazionale della Società Chimica Italiana, Divisione di Chimica dei Sistemi Biologici, Università «La Sapienza», Roma (Italy), December 9-11, 1993, pp. 78-79.

[P13] E. Borghi, M. Occhiuzzi, F. Laschi, M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi, P. Rovero. Histidyl-glycyl containing peptides: a spectroscopic characterization of Copper(II) interaction with the linear octapeptide H-(L-His-Gly)4-OH. Metal ions in Biological Systems, Eurobic II, Firenze (Italy), August 30-September 3, 1994, p. 61.

[P14] E. Borghi, M. Occhiuzzi, F. Laschi, M. Chelli, M. Ginanneschi, A.M. Papini, G. Rapi. L-histidyl-glycyl containing linear and cyclopeptides. Comparative results for the interactions with Copper (II) ion. III Convegno nazionale della Società Chimica Italiana, Divisione di Chimica dei Sistemi Biologici, Università «La Sapienza», Roma (Italy), January 25-27, 1995, P-20.

[P15] M. Chelli, M. Ginanneschi, A.M. Papini, D. Pinzani, G. Rapi, G. Giorgi, F. Laschi, E. Borghi, M. Occhiuzzi. Complexation properties of histidyl-glycyl containing peptides. A mass spectrometry study of H-(L-His-Gly)2-OMe cationized with metal ions. III Convegno nazionale della Società Chimica Italiana, Divisione di Chimica dei Sistemi Biologici, Università «La Sapienza», Roma (Italy), January 25-27, 1995, P-21.

[P16] A.M. Papini, M. Biondi, D. Pinzani, M. Chelli, M. Ginanneschi, G. Rapi, B. Mazzanti, M. Vergelli, L. Massacesi, L. Amaducci. Sintesi di lipopeptidi dell’epitopo immunodominante della proteina basica della mielina nel ratto Lewis e caratterizzazione delle proprietà encefalitogene. III Convegno nazionale della Società Chimica Italiana, Divisione di Chimica dei Sistemi Biologici, Università «La Sapienza», Roma (Italy), January 25-27, 1995, P-48.

[P17] G. Giorgi, M. Chelli, M. Ginanneschi, F. Laschi, A.M. Papini, D. Pinzani, E. Borghi, M. Occhiuzzi, G. Rapi. A Mass Spectrometry study of H-(L-His-Gly)2-OMe cationized with metal ions. 14th American Peptide Symposium, Columbus (Ohio, USA), June 18-23, 1995, P-262, p. 2-87.

[P18] A.M. Papini, M. Biondi, D. Pinzani, S. Mazzucco, M. Chelli, M. Ginanneschi, G. Rapi, B. Mazzanti, M. Vergelli, L. Massacesi, L. Amaducci. Lipopeptides of the immunodominant epitope of myelin basic protein in Lewis rats and characterization of their encephalitogenic properties. 14th American Peptide Symposium, Columbus (Ohio, USA), June 18-23, 1995, P-444, p. 2-122.

[P19] D. Pinzani, A.M. Papini, M.E. Vallecchi, M. Chelli, M. Ginanneschi, C.A. Maggi, R. Patacchini, M. Astolfi, L. Quartara, G. Rapi. Synthesis and biological activities of glycopeptides of NK2 receptor antagonists. 14th American Peptide Symposium, Columbus (Ohio, USA), June 18-23, 1995, P-586, p. 2-154.

[P20] M. Ginanneschi, M. Chelli, A.M. Papini, D. Pinzani, G. Rapi, M. Ciuffi, L. Tarlini. In vitro radical scavenger activity of H-(L-His-Gly)₂-OH Copper (II) complexes. 40° Congresso Nazionale della Società Italiana di Biochimica, Torino (Italy), September 12-15, 1995. Italian Biochemical Society Transactions (IBST) Mini-paper, (1995), 6, P-117.

[P21] L. Tarlini, M. Ciuffi, S. Franchi-Micheli, S. Mugnai, L. Zilletti, M. Ginanneschi, M. Chelli, A.M. Papini, G. Rapi, F. Paoletti. Effect of H-(L-His-Gly)₂-OH/Cu(II) complexes on in vitro, ex vivo, and in vivo models of tissue damage mediated by reactive oxygen species. Riunione congiunta monotematica sul metabolismo degli xenobiotici delle Società Italiane di Farmacologia e di Tossicologia, Siena (Italy), November 3-4, 1995, Poster p.65.

[P22] A.M. Papini, S. Mazzucco, M. Chelli, M. Ginanneschi, G. Rapi, G. Caminati, G. Gabrielli. Conformational studies on lipopeptides of human myelin basic protein at the air-water interphase. 15th American Peptide Symposium, Nashville (Tennessee, USA), June 14-19, 1997, Abstract P220, p. 2-124.

[P23] A.M. Papini, S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, B.Mazzanti, M. Vergelli, L. Massacesi, L. Amaducci, G. Rapi. Comparative study of the proliferative response of hMBP lipopeptides containing amide or C-C bond linked alkyl chains. 42° Congresso Nazionale della Società Italiana di Biochimica, Ancona (Italy), September 24-27, 1997. Italian Biochemical Society Transactions (IBST) Mini-paper, (1997), 9, P-8.10, p. 304.

[P24] G. Caminati, G. Gabrielli, A.M. Papini, S. Mazzucco. Lipopeptides of myelin basic protein in mono and multilayer. LB8 International Conference on Langmuir-Blodgett Films, Asilomar, California USA, August 24-30, 1997.

[P25] S. Mazzucco, E. Nardi, M. Chelli, M. Ginanneschi, G. Rapi, M. Vergelli, B. Mazzanti, E. Treggiai, L. Massacesi, A.M. Papini. Comparison of the T cell proliferative response to lipopeptides of hMBP(83-99) and hMBP(141-160) in multiple sclerosis patients. 25th European Peptide Symposium, Budapest (Hungary), August 30-September 4, 1998, Abstract P298, p. 8.

[P26] S. Matà, F. Lolli, F. Pinto, S. Mazzucco, R. Fioresi, M. Chelli, M. Ginanneschi, A.M. Papini, B. Mazzanti, L. Massacesi and M. Vergelli. Antibodies to a glycopeptide of human MOG in multiple sclerosis and other neurological diseases. IX Congresso Nazionale AINI (Associazione Nazionale Neuroimmunologia), Chieti (Italy), October 28-30, 1998.

[P27] B. Mazzanti, M. Vergelli, E. Traggiai, C. Ballerini, L. Massacesi, A.M. Papini, S. Mazzucco, D. Pinzani, M. Biondi, M. Chelli, M. Ginanneschi, G. Rapi. Lipoderivatives of an immunodominant epitope of myelin basic protein increased T cell responsiveness. IX Congresso Nazionale AINI (Associazione Italiana di Neuroimmunologia), Chieti (Italy), October 28-30, 1998.

[P28] A.M. Papini, R. Fioresi, S. Mazzucco, E. Nardi, S. Matà, F. Lolli, M. Vergelli, M. Chelli, M. Ginanneschi, B. Mazzanti, L.Massacesi, F. Pinto. Asn³¹[N-Glucosyl]hMOG(30-50): a useful antigen to identify anti-MOG antibodies in multiple sclerosis patients. 10^th International Congress of Immunology, New Delhi (India), November 1-6, 1998, Abstract P-189.

[P29] G. Caminati, G. Gabrielli, S. Mazzucco, A.M. Papini. Caratterizzazione di peptidi all’interfase acqua aria. Congresso Nazionale di Chimica-Fisica 1998, Capo Taormina (Italy), September 1998, Abstract P30, p. 122-123.

[P30] B. Anichini, M.C. Alcaro, L. Quartara, M.R. Altamura, M. Chelli, M. Ginanneschi, A.M. Papini. Synthetic pathways leading to protected 3,4-didehydroornithine for SPPS strategy. 16th American Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P016.

[P31]A.M. Papini, E. Nardi, S. Mazzucco, B. Mazzanti, E. Traggiai, C. Ballerini, H. Kalbacher, H. Beck, M. Chelli, M. Ginanneschi, L. Massacesi and M. Vergelli. T-Cell response to lipoderivatives of different MBP peptide antigens correlates with their suceptibility to peptidases. 16th American Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P153.

[P32]G. Sabatino, A. Di Fenza, M. Chelli, M. Ginanneschi, P. Rovero, A.M. Papini.

Allyl esters of amino acids linked to trityl-resin by their side-chain as useful starting supports to obtain diketopiperazine based combinatorial libraries. 16thAmerican Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P220.

[P33] E. Nardi, S. Mazzucco, S. Matà, M. Chelli, B. Mazzanti, E. Traggiai, M. Ginanneschi, F. Pinto, L. Massacesi, M. Vergelli, H. Kalbacher, F. Lolli, A.M. Papini. Influence of different N-linked glycosyl moiety at position 31 of hMOG(30-50) on anti-MOG antibody recognition in multiple sclerosis patients. 16thAmerican Peptide Symposium, Minneapolis (Minnesota, USA), June 26-July 1, 1999, Abstract P148. Bruce W. Erickson Award. Third Place for outstanding achievement in peptide sciences, July 1, 1999, Minneapolis (Minnesota, USA).

2000

[P34] E. Peroni, G. Caminati, P. Baglioni, M. Chelli, A.M. Papini. Caratterizzazione fotofisica dell’interazione di lipopeptidi con modelli di membrana. XX Congresso nazionale della Società Chimica Italiana, Rimini (Italia), June, 4-9, 2000, Abstract NS-PO006.

[P35] E. Nardi, M. Chelli, M. Ginanneschi, S. Meini, L. Quartara, M.R. Altamura, C.A. Maggi, F. Formaggio, C. Toniolo, Q.B. Broxterman, P. Rovero, A.M. Papini. Lipophilic modifications of bradykinin agonists. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, J. Pept. Sci., Supplement to Vol. 6, 2000, S 216, Abstract P457.

[P36] J. Uziel, M.C. Alcaro, G. Sabatino, A. Di Fenza, M. Ginanneschi, M. Chelli, P. Rovero, A.M. Papini. A Synthetic Strategy Toward Constrained Head-to-Tail Cyclopeptides Libraries by Amino Acid Side Chain Anchoring to Trityl Resins. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, J. Pept. Sci., Supplement to Vol. 6, 2000, S 103, Abstract P058.

[P37] E. Nardi, E. Mastrangelo,S. Matà, B. Mazzanti, V. Zipoli,M. Chelli, M. Ginanneschi, L. Massacesi, M. Vergelli,F. Lolli, F. Pinto, A.M. Papini. Role of the Glycosyl Moiety in Autoantibody Recognition in Multiple Sclerosis. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, J. Pept. Sci., Supplement to Vol. 6, 2000, S 208, Abstract P433.

[P38] A.M. D’Ursi, A. Carotenuto, E. Nardi, E. Mastrangelo, A.M. Papini, P. Rovero. Conformational Studies on glycopeptide fragments of human myelin oligodendrocyte glycoprotein. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, J. Pept. Sci., Supplement to Vol. 6, 2000, S 138, Abstract P166.

[P39] E.. Peroni, G. Caminati, P. Baglioni, M. Chelli, A.M. Papini. A New Fluorescent Probe to Mimic Lipophilic Moieties for Interaction Studies of Bioactive Lipopeptides with Membrane Models. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, J. Pept. Sci., Supplement to Vol. 6, 2000, S 227, Abstract P494.

[P40] M.C. Alcaro, A.M. Papini, M. Chelli, D.Fishlock, C. Atkins, G.A. Lajoie. Stereoselective Syntheses of b,g-Unsaturated amino acids. 26th European Peptide Symposium, Montpellier (France), September 11-15, 2000, J. Pept. Sci., Supplement to Vol. 6, 2000, S 119, Abstract P101.

[P41] A.M. D’Ursi, A. Carotenuto, E. Nardi, E. Mastrangelo, A.M. Papini, F. Lolli, F. Pinto, P. Rovero. Conformational Studies on a new synthetic MOG glycopeptide antigen able to block demyelinating antibodies in multiple sclerosis. 26^th International Symposium of Medicinal Chemistry, Bologna (Italy), September 18-22, 2000.

2001

[P42] A.M. Papini, M.C. Alcaro, M. Chelli, M. Ginanneschi. Cyclic pentapeptide metal ion complexation: a model of the binding unit of the Prion protein. EUROCOMBI-1, Budapest (Hungary), 1-5 July, 2001.

[P43] M.C. Alcaro, M. Chelli, A.M. Papini. Parallel solid phase synthesis of lipophilicg,d-unsaturated amino acids. EUROCOMBI-1, Budapest (Hongrie), 1-5 Juillet, 2001.

[P44] A.M. Papini, E. Nardi, B. Mazzanti, T. Biagioli, E. Traggiai, C. Ballerini, M. Chelli, H. Kalbacher, L. Massacesi, M. Vergelli. Different effect of lipoconjugation of MBP peptides for CD4+ T cell response. 11^th International Congress for Immunology, Stockholm (Sweden), 22-27 Juillet, 2001.

[P45] A.M. Papini, S. Matà, E. Nardi, B. Mulinacci, M. Chelli, A. Carotenuto, P. Rovero, F. Pinto, L. Massacesi, M. Vergelli, F. Lolli. Specific role of Asn(Glc) in autoantibody recognition to glycosylated peptides in Multiple Sclerosis. 11^th International Congress for Immunology, Stockholm (Sweden), 22-27 Juillet, 2001.

2002

[P46] M. Ginanneschi, S. Mazzucco, A. Carotenuto, P. Rovero, A.M. Papini, M. Chelli, G. Sabatino. Synthesis of a new octreotide analogue for studies in clinical oncology. Convegno Nazionale della Divisione di Chimica dei Sistemi Biologici, “From Genes to Molecules”, Certosa di Pontignano, Siena (Italy), 8-10 February, 2002, Book of Abstracts, PC36, p. 68.

[P47] M.C. Alcaro, T. Terzani, F. Nuti, M. Chelli, M. Ginanneschi, F. Machetti, A. Brandi, L. Quartara, C.A. Maggi, A.M. Papini. Study of the role of basic residues in peptide bradykinin antagonists. 23rd IUPAC 2002, International Symposium on the Chemistry of Natural Products, 28 July-2 August, 2002, Firenze (Italy), Abstract Book, P7, p. 133.

[P48] G. Sabatino, M. Chinol, G. Paganelli, M. Chelli, G. Leone, D. Fanucci, A.M. Papini, M. C. Alcaro, M. Ginanneschi. Synthesis and in vitro stability of a new Vitamin H derivative conjugated to DOTA and carrying radioactive metals. 23rd IUPAC 2002, International Symposium on the Chemistry of Natural Products, 28 July-2 August, 2002, Firenze (Italy), Abstract Book, P88, p. 214.

[P49] F. Machetti, F. Cordero, F. De Sarlo, A.M. Papini, A. Brandi. Studies toward Synthesis of enantiopure 4-substituited pipecolic acids. 23rd IUPAC 2002, International Symposium on the Chemistry of Natural Products, 28 July-2 August, 2002, Firenze (Italy), Abstract Book, P136, p. 265.

[P50] M.C. Alcaro, G. Sabatino, M. Ginanneschi, M. Chelli, A. Di Fenza, P. Rovero, A.M. Papini. A synthetic strategy toward constrained head-to-tail cyclopeptides. 27th European Peptide Symposium, Sorrento (Italy), 31 August- 6 September, 2002, J. Pept. Sci., 2002, 8(Suppl.), S78, Abstract P A1.

[P51] F. Nuti, F.M. Cordero, E. Peroni, M. Chelli, A.M. Papini, A. Brandi. Synthesis of new Fmoc-protected iminosugars to study the role of the glycosyl moiety in autoantibody recognition in autoimmune diseases. 27th European Peptide Symposium, Sorrento (Italy), 31 August- 6 September, 2002, J. Pept. Sci., 2002, 8(Suppl.), S103, Abstract P A103.

[P52] G. Sabatino, B. Mulinacci, M. C. Alcaro, M. Ginanneschi, M. Chelli, P. Rovero, A.M. Papini. A comparative study of coupling reagents for automatic multiple peptide synthesizers. 27th European Peptide Symposium, Sorrento (Italy), 31 August- 6 September, 2002, J. Pept. Sci., 2002, 8(Suppl.), S91, Abstract P A56.

[P53] E. Peroni, F. Lolli, B. Mulinacci, F. Nuti, B. Mazzanti, S. Matà, M. Chelli, F. Pinto, P. Rovero, A.M. Papini. Innovative biocompatible immunoadsorbents containing immobilized selective glycopeptide antigens for Multiple Sclerosis therapy. 27th European Peptide Symposium, Sorrento (Italy), 31 August- 6 September, 2002, J. Pept. Sci., 2002, 8(Suppl.), S152, Abstract P C27.

[P54] M.C. Alcaro, B. Anichini, T. Terzani, F. Nuti, M. Chelli, F. Machetti, L. Quartara, C. A. Maggi, A. Brandi, A.M. Papini. New constrained amino acids for the study of the role of the basic residues in bradykinin antagonists. 27th European Peptide Symposium, Sorrento (Italy), 31 August- 6 September, 2002, J. Pept. Sci.,2002, 8(Suppl.), S95, Abstract P A72.

[P55] B. Mulinacci, E. Peroni, G. Sabatino, S. Matà, M. Chelli, A. Carotenuto, P. Rovero, F. Pinto, F. Lolli, A.M. Papini. Toward rationally designed glycopeptide antigens recognizing autoantibodies in Multiple Sclerosis patients. 27th European Peptide Symposium, Sorrento (Italy), 31 August- 6 September,  2002, J. Pept. Sci., 2002, 8(Suppl.), S141, Abstract P B47.

[P56] B. Mulinacci, E. Peroni, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, S. Matà, B. Mazzanti, F. Lolli, A.M. Papini. Progettazione razionale di glicopeptidi da utilizzare in test Elisa per il monitoraggio della sclerosi multipla. XXVIII Convegno Nazionale della Divisione di Chimica Organica, Romea (Italy), 16-20 September, 2002, Abstract P31.

[P57] M.C. Alcaro, G. Sabatino, M. Ginanneschi, M. Chelli, P. Rovero, A.M. Papini. Strategia di sintesi in fase solida di librerie di dichetopiperazine e di ciclopeptidi RGD. XXVIII Convegno Nazionale della Divisione di Chimica Organica della S.C.I., Roma (Italy), 16-20 September, 2002,Abstract P42.

[P58] E. Peroni, G. Caminati, P. Baglioni, F. Nuti, M. Chelli, A.M. Papini. Sintesi di un nuovo probe fluorescente per lo studio di lipopeptidi come vaccini sintetici per la sclerosi multipla. XXVIII Convegno Nazionale della Divisione di Chimica Organica della S.C.I., Roma (Italy), 16-20 September, 2002, Abstract P67.

[P59] F. Nuti, S. Hildebrand, M. Chelli, A. Brandi, A.M. Papini. Sintesi di metaboliti del di-2-etilesilftalato per la valutazione dei rischi tumorali da ftalati nell’uomo. XXVIII Convegno Nazionale della Divisione di Chimica Organica della S.C.I., Roma (Italy) , 16-20 September, 2002, Abstract P87.

[P60] G. Sabatino, B. Mulinacci, M. C. Alcaro, M. Chelli, P. Rovero, A.M. Papini. Studio comparativo di reagenti di accoppiamento per sintetizzatore automatico multiplo. XXVIII Convegno Nazionale della Divisione di Chimica Organica della S.C.I., Roma (Italy), 16-20 September, 2002, Abstract P108.

2003

[P61] M.C. Alcaro, M. Chelli, P. Rovero, A.M. Papini. Strategy to constrained cyclopeptide libraries. QSAR & Combinatorial Science. Vol. 22 n.4. June, 2003, P1, p. 47.

[P62] A. Innocenti,M.C. Alcaro, M. Chelli, P. Rovero, A.M. Papini. Synthesis and screening of a library  of 4-sulfamoylphenylthioureas for the development of carbonic anhydrase inhibitors. QSAR & Combinatorial Science. Vol. 22 n.4. June, 2003,P22, p.52.

[P63] V. Vinci, M.C. Alcaro, M. Chelli, S. Giuliani, S. Meini, M. Di Giacomo, L. Colombo, A.M. Papini. Synthesis of bradykinin B2 antagonist containing dipeptide mimetics. XXI Congresso Nazionale della Società Chimica Italiana, Torino (Italy), 22-27 June, 2003, Atti Vol 2 SB-CP-001.

[P64] B. Mulinacci, E. Peroni, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, B. Mazzanti, M. Pazzagli, M.C. Pozo-Carrero, F. Lolli, A.M. Papini. Structure-activity relationship study of glycopeptide antigens recognizing specific autoantibodies in Multiple Sclerosis. XXI Congresso Nazionale della Società Chimica Italiana, Torino (Italie), 22-27 June, 2003, Atti Vol 2, SB-CP-023.

[P65] F. Nuti, I. Paolini, E. Peroni, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, F. Lolli, M. Chelli, F. Cordero, A. Brandi, A.M. Papini. Sugar-scan of CSF114(Glc) for autoantibodies recognition in autoimmune disease. XXI Congresso Nazionale della Società Chimica Italiana, Torino (Italy), 22-27 June, 2003, Atti Vol 2, SB-CP-024.

[P66]M.C. Alcaro, M. Orfei,A.M. Papini, M. Chelli, M. Ginanneschi. A new solid-phase strategy leading to tetraazamacrocycles. XXI Congresso Nazionale della Società Chimica Italiana, Torino (Italy), 22-27 June, 2003,  Atti Vol 2, SB-CP-025.

[P67] E. Peroni, F. Lolli, B. Mulinacci, F. Nuti, M. Chelli, P. Rovero, A.M. Papini. Innovative biocompatible immunoadsorbents containing immobilized selective glycopeptide antigens for Multiple Sclerosis therapy. XXI Congresso Nazionale della Società Chimica Italiana , Torino (Italy), 22-27 June, 2003, Atti Vol 2, SB-CP-028.

[P68]G. Sabatino, M. C. Alcaro, M. C. Pozo-Carrero, M. Chelli, P. Rovero, A.M. Papini. Assessment of 6Cl-HOBt-based coupling reagents in solid-phase cyclopeptide synthesis. 18th American Peptide Symposium, Boston, MA, USA, 19-23 June, 2003, P 004, Abstract p. 306.

[P69]E. Peroni, F. Lolli, B. Mazzanti, M. Pazzagli, B. Bonetti, J. Hoebeke, L. Massacesi, M. Chelli, P. Rovero, A.M. Papini. Towards a therapeutic apheresis in Multiple Sclerosis based on a glycopeptide antigen able to isolate specific autoantibodies. 18th American Peptide Symposium, Boston, MA, USA, 19-23 June, 2003, P 027, Abstract p. 311.

[P70]B. Mulinacci, F. Nuti, G. Sabatino, M. Chelli, A. Carotenuto, P. Rovero, B. Mazzanti, M. Pazzagli, F. Lolli, A.M. Papini. Structure-activity relationship study of glycopeptide antigens recognizing specific autoantibodies in Multiple Sclerosis. 18th American Peptide Symposium, Boston, MA, USA, 19-23 June, 2003, P 040, Abstract p. 314.

[P71]F. Nuti, I. Paolini, B. Mulinacci, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, F. Lolli, M. Chelli, F. Cordero, A. Brandi, A.M. Papini. Sugar–Scan of CSF114(Glc) for autoantibody recognition in autoimmune diseases. 18th American Peptide Symposium, Boston, MA, USA, 19-23 June, 2003, P 041, Abstract p. 314.

[P72]A.M. Papini, B. Mulinacci, E. Peroni, F. Nuti, G. Sabatino, M.C. Pozo-Carrero, B. Mazzanti, M. Pazzagli, L. Massacesi, M. Chelli, P. Rovero, F. Lolli. MS PepKit, the first diagnostic test based on CSF114(Glc) a glycopeptide to follow-up Multiple Sclerosis. 18th American Peptide Symposium, Boston, MA, USA, 19-23 June, 2003, P 454, Abstract p. 401.

2004

[P73] M.C. Alcaro, E. Naldini, B. Mulinacci, B. Mazzanti, M. Pazzagli, F. Lolli, M. Chelli, P. Rovero, A.M. Papini. Identification of new autoantigens in Multiple Sclerosis by glycopeptide libraries. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, AbstractP125.

[P74] B. Mulinacci, I. Paolini, A. Carotenuto, B. Mazzanti, M. Pazzagli, M. Chelli, F. Lolli, P. Rovero, A.M. Papini. β-hairpin glycopeptides as mimetic autoantigens in Multiple Sclerosis. 3^rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, AbstractP303.

[P75] I. Paolini, F. Nuti, B. Kolesinska, F. Cardona, M. Chelli, B.Mazzanti, F. Lolli, A. Brandi, A.M. Papini. Optimisation of synthetic strategies to glycosylated amino acids. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P306.

[P76] E. Peroni, F. Peri, F. Nuti, B. Mazzanti, M. Chelli, A.M. Papini. An innovative approach to the synthesis of N-glycopeptides. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P307.

[P77] G. Sabatino, B. Kolesinska, M. Chelli, P. Rovero, Z. J. Kaminski, A.M. Papini. A comparative study on new not azabenzotriazole-based coupling reagents for SPPS. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P56.

[P78] M.C. Pozo Carrero, B. Kolesinska, G. Sabatino, M. Chelli, P. Rovero, Z.J. Kaminski, A.M. Papini. Synthesis of useful building blocks for peptide synthesis: a comparative study of different coupling reagents for ester and amide bonds. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P51.

[P79] J. Kolesinska, B. Kolesinska, A.M. Papini, Z.J. Kaminski. N-Triazinylammonnium tetrafluoroborates as new, highly efficient coupling reagents for peptide synthesis in solution. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P106.

[P80] K. Jastrząbek, M. Błaszczyk, M.L. Główka, B. Kolesinska, A.M. Papini, Z.J. Kaminski. 2-Chloro-4,6-dibenzyloksy-1,3,5-triazine and N-(3,5-dibenzyloxy-1,3,5-triazinyl-1)ammonium tetrafluoroborates as highly efficient coupling reagents for peptide synthesis in solution. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P105.

[P81] B. Kolesinska, G. Sabatino, J. Kolesinska, M. Chelli, P. Rovero, Z.J. Kaminski, A.M. Papini. New generation of triazine-based coupling reagents useful for SPPS. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P33.

[P82] A.M. Papini, B. Kolesinska, G. Sabatino, J. Kolesinska, Z.J. Kaminski. Selection of the best triazine-based condensing reagent for SPPS. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P49.

[P83] D. D’Addona, M. Chelli, A.M. Papini, F. Bucelli, A. Carotenuto, M. Ginanneschi. Synthesis and conformational studies of a new octreotide analogue. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P17.

[P84] M. Orfei, M. Chelli, A.M. Papini, M. Ginanneschi. A solid-phase synthesis of tetrazaamacrocycles from cyclotetrapeptides. 3^rd International and 28^th European Peptide Symposium, Prague, Czech Republic, 5-10 September, 2004, Abstract P48.

[P85] B. Mazzanti, M. Pazzagli, M.C. Alcaro, B. Mulinacci, E. Peroni, F. Nuti, G. Sabatino, M.C. Pozo-Carrero, A. Carotenuto, B. Bonetti, L. Battistini, D. Franciotta, S. Sotgiu, R. Lanzillo, M. Chelli, P. Rovero, F. Lolli, A.M. Papini. A proteomic approach to characterize a native antigen involved in autoantibody response in Multiple Sclerosis by a structure-based designed glycopeptide. Seventh International Congress of the International Society of Neuroimmunology, Venezia (Italy) 28 September-2 October, 2004, Abstract 313 in: J. Neuroimmunol. (2004) 154, 95.

2005

[P86] M.C. Alcaro, P. Rovero, A.M. Papini. Fishing for antigens recognizing autoantibodies in Multiple Sclerosis. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 June, 2005, PY 20, Abstract p. 507.

[P87] E. Bulukin, E. Peroni, M. Minunni, M. Pazzagli, P. Rovero, M. Mascini, A.M. Papini. Development of an efficient Multiple Sclerosis diagnostic technique based on an optical glycopeptide immunosensor. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 June, 2005.

[P88] E. Peroni, M.C. Alcaro, F Barbetti, F. Nuti, F. Real-Fernàndez, B. Mazzanti, M.Chelli, P. Rovero, A.M. Papini. Combinatorial approach to develop the optimal glycopeptide as molecular probe to characterize autoantibodies in Multiple Sclerosis. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 June, 2005, PY 46, Abstract p. 512.

[P89] F. Nuti, I. Paolini, B.Mazzanti, F. Real-Fernàndez, M.C. Pozo-Carrero, M. Chelli, P.Rovero, A.M. Papini. Asparaginyl glucose is fundamental for autoantibody recognition in Multiple Sclerosis. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 June, 2005, PY 17, Abstract p. 507.

[P90] G. Sabatino, I. Paolini, M.C. Pozo-Carrero, M. Chelli, P. Rovero, A.M. Papini. Optimized conditions for glycopeptide synthesis by a microwave peptide synthesizer. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 June, 2005, PY 16, Abstract p. 507.

[P91] I. Paolini, F. Nuti, I. Matteini, G. Sabatino, M. Chelli, A.M. Papini. Microwave-assisted synthesis of glycosylated building blocks. 19th American Peptide Symposium, San Diego, CA, USA, 18-24 June, 2005, PY 15, Abstract p. 507.

[P92] E. Peroni, E. Bulukin, M. Minunni, M. Pazzagli, P. Rovero, M. Mascini, A.M. Papini. Development of a high-throughput screening for Multiple Sclerosis patients’ sera based on an optical glycopeptide immunosensor. EUROCOMBI-3 conference, Winchester, U.K. 18-21 June, 2005. Abstract P98