Personale

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Orario di ricevimento

Italiano

Biografia

Curriculum

Pubblicazioni

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English

Curriculum

Teresa IANTOMASI

Ruolo attuale:: Ricercatore
SSD:: BIOS-07/A - Biochimica
Afferenza organizzativa:: Dipartimento di Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'

Recapiti

	0552758146
	teresa.iantomasi(AT)unifi.it

Teresa IANTOMASI

Curriculum

Maturità classica

1983 Laurea in Scienze Biologiche presso l'Università degli Studi di Firenze, discutendo una tesi sperimentale di Biochimica dal titolo “Azione di detergenti sugli enzimi idrolitici”.

1983-1984 Tirocinio pratico presso l’Istituto di Chimica Biologica e la Clinica Ostetrica e Ginecologica II dell’Università degli Studi di Firenze

1983-1988. Attività di ricerca volontaria e gratuita nell’Istituto di Chimica Biologica, diventato poi Dipartimento di Scienze Biochimiche.

1988. Borsa di Dottorato di Ricerca in Biochimica presso l’Università degli studi di Firenze.

1990. Collaboratore Tecnico presso il Dipartimento di Scienze Biochimiche dell’Università degli Studi di Firenze.

1993. Dottore di Ricerca in Biochimica

1998. Ricercatore universitario (settore scientifico disciplinare BIO10) presso la facoltà di Farmacia assegnato al Dipartimento di Scienze Biochimiche.

2005-2010 componente del Gruppo di Autovalutazione (GAV) per redigere il Rapporto di Autovalutazione (RAV) per il corso di laurea in Tossicologia dell'Ambiente della Facoltà di Farmacia dell'Università degli Studi di Firenze.

Dal 2013 a tutt’oggi è membro della commissione didattica per il corso di laurea in Chimica e Tecnologia Farmaceutiche (CTF) dell’Università degli Studi di Firenze

Attività didattica svolta presso l’Università degli Studi di Firenze

•   Dal 1983 al 1988, come cultore della materia per Chimica e Propedeutica Biochimica e per Biologia e Zoologia generale del corso di laurea in Medicina e Chirurgia, ha fatto parte delle commissioni giudicatrici ed ha svolto attività di tutoraggio; ha tenuto esercitazioni teorico pratiche e seminari per la Chimica Biologica del corso di laurea in Medicina e Chirurgia
•   Dal 1992 ha tenuto esercitazioni e seminari ed ha fatto parte delle commissioni giudicatrici per la Biochimica Applicata e la Chimica Biologica del corso di laurea in Chimica e Tecnologia Farmaceutiche (CTF) della Facoltà di Farmacia.
•   Dal 1998 al 2017 ha tenuto lezioni di Metodologie Biochimiche per la scuola di specializzazione in Biochimica e Chimica Clinica della Facoltà di Medicina e Chirurgia.
•   Dagli AA 1998-1999 agli AA 2011-2012 la Facoltà di Farmacia le ha assegnato, per la Biochimica del corso di laurea in CTF, un modulo di insegnamento di 10 ore.
•   Dagli AA 1998-1999 agli AA 2000-2001 la Facoltà di Farmacia le ha assegnato un modulo di insegnamento di 30 ore per la Biochimica Applicata del corso di laurea in CTF.
•   Dall’AA 2001-2002 ad oggi la Facoltà di Farmacia prima e la Scuola di Scienze della salute umana ora le ha assegnato, in qualità di titolare, l’insegnamento della Biochimica Applicata del corso di laurea in CTF.
•   Dagli AA 2004-2005 agli AA 2008-2009 le è stato affidato un modulo di 8 ore per l’insegnamento di Biochimica nel corso di laurea in Tossicologia dell’Ambiente (Facoltà di Farmacia).
•   Nel 2009-2010 ha tenuto per il corso di laurea in Biotecnologie (Interfacoltà) l’insegnamento di Laboratorio di Biologia e Microbiologia (Modulo Metodologie Biomolecolari I).
•   Dal 2012 al 2019 è entrata a far parte del collegio dei docenti del Dottorato di ricerca “Biochimica e Biologia molecolare” dell’Università degli Studi di Siena.
•   Svolge attività di tutoraggio, e segue vari studenti per la preparazione delle loro tesi di laurea e per diversi di essi è correlatrice o relatrice.

Attività scientifica

Ha fatto parte dei gruppi di ricerca (Responsabili Scientifici Prof. Francesco Tonelli o Prof. Maria Teresa Vincenzini) in progetti finanziati dall'Ente Cassa di Risparmio di Firenze

Come membro dell’Unità di Ricerca (Responsabile scientifico Prof. Maria Teresa Vincenzini) ha partecipato al progetto PRIN finanziato nel 1998 dal titolo “Glutatione e attività di recettori di membrana in relazione allo stato redox intracellulare”.

Ha fatto parte dell’Unità di ricerca (Responsabile Scientifico Prof. Francesco Tonelli) nel progetto PRIN 2007, considerato finanziabile ma non finanziato dal MIUR per mancanza di fondi, dal titolo “Caratterizzazione della risposta infiammatoria "in vitro" di miofibroblasti intestinali di pazienti affetti da malattie infiammatorie croniche intestinali (IBD): influenza dell'espressione dei recettori estrogenici, del polimorfismo arg381gln del gene il23r e delle varianti alleliche del gene card15/nod2”.

Dal primo novembre 2020, è Responsabile Scientifico dell'Unità di Ricerca del progetto PRIN 2017 (Coordinatore Scientifico Prof.ssa Giovanna Mantovani) Titolo: Physiopathology, Epidemiology and Genetics of primary pArathyroid hormone deficiency and reSistance: a mUlticenter italian Study (PEGASUS).

Dal primo novembre 2020 è Responsabile Scientifico dell’Unità di Ricerca e del Laboratorio “Laboratory for the study of endocrine tumours, mineral metabolism diseases, musculoskeletal pain and redox regulated mechanisms.” Della Sez. di Biochimica del Dipartimento di Scienze Biomediche Sperimentali e Cliniche “Mario Serio”, Università degli Studi di Firenze. Laboratorio che svolge la propria attività scientifica nell’ambito degli effetti metabolici della Vitamina D e dei suoi derivati, della patogenesi dei disordini paratiroidei, della MEN1 e della MEN2, della regolazione redox dei processi biologici, della biologia cellulare dell’osso, delle patologie muscolo-scheletriche, della biologia cellulare del tessuto muscolare e dei cannbinoidi e dei loro effetti biologici.

Ha partecipato e partecipa in qualità di membro/presidente a commissioni per il reclutamento di assegnisti e borsisti per alcuni dei quali è stato ed è responsabile scientifico.

Le principali attività di ricerca hanno riguardato i seguenti argomenti:

•Variazioni metaboliche ed influenza della vitamina D e suoi derivati [25 OH D3 e 1,25 (O H)2D3] nei sistemi di trasporto transmembrana di metaboliti quali glucosio, citrato, aminoacidi, in organi di ratti tenuti a dieta carente di tale vitamina.

•Influenza dell'invecchiamento nell'attività del sistema di trasporto Na+ dipendente del glucosio in membrane di brush-border di intestino umano ed in brush-border intestinali e renali di ratto.

•Correlazioni tra il ruolo biologico antiossidante del glutatione (GSH) e degli enzimi glutatione dipendenti ed il processo di invecchiamento cerebrale in corteccia e in sinaptosomi di cervello di ratto.

•Individuazione e caratterizzazione di specifici sistemi di trasporto transmembrana del glutatione e dei suoi derivati in membrane di brush-border intestinali, in membrane di sinaptosomi di corteccia cerebrale di ratto, in cellule embrionali intestinali umane (I407) e in fibroblasti NIH3T3 murini.

•Correlazione tra metabolismo del glutatione, trasformazione oncogenica e farmaco-radioresistenza.

•Ruolo del glutatione nella proliferazione cellulare in relazione ai meccanismi di trasduzione dei segnali mitogenici.

• Studio di meccanismi molecolari, coinvolti nella patologia del morbo di Crohn, correlati a produzione di ROS, adesione, apoptosi, sintesi di citochine e fibrosi.

• Ruolo dello stress ossidativo e dei riducenti nell’attività osteogenica di osteoblasti e osteociti e nel rimodellamento osseo.

• Studio dei meccanismi molecolari e targets (es. Non-coding RNA) alla base di alcune patologie del metabolismo osseo.

L'attività scientifica è documentata da numerose pubblicazioni internazionali e da partecipazioni a congressi nazionali ed internazionali.

Teresa IANTOMASI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

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Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

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Tesi di Dottorato

Irene Falsetti, Gaia Palmini, Simone Donati, Cinzia Aurilia, Teresa Iantomasi, Maria Luisa Brandi (2024). Irisin and its role in postmenopausal osteoporosis and sarcopenia. BIOMEDICINES, pp. 0-0, ISSN:2227-9059

Maria Luisa Brandi; Francesca Marini; Simone Parri; Stefania Bandinelli; Teresa Iantomasi; Francesca Giusti; Eleonora Talluri; Giovanna Sini; Fabrizio Nannipieri; Santina Battaglia; Giovanni Tripepi; Colin Gerard Egan; Luigi Ferrucci (2024). Association of vitamin D and bisphenol A levels with cardiovascular risk in an elderly Italian population: results from the InCHIANTI study. GEROSCIENCE, pp. 0-0, ISSN:2509-2723

Irene Falsetti, Gaia Palmini,Teresa Iantomasi, Maria Luisa Brandi, and Francesco Tonelli (2024). Mechanisms of action of phytoestrogens and their role in familial adenomatous polyposis. PHARMACEUTICS, pp. 0-0, ISSN:1999-4923

Simone Donati, Gaia Palmini, Cinzia Aurilia, Irene Falsetti, Francesca Marini, Francesca Giusti, Teresa Iantomasi, Maria Luisa Brandi (2023). Calcifediol: mechanisms of action. NUTRIENTS, pp. 0-0, ISSN:2072-6643

Iantomasi, Teresa; Romagnoli, Cecilia; Palmini, Gaia; Donati, Simone; Falsetti, Irene; Miglietta, Francesca; Aurilia, Cinzia; Marini, Francesca; Giusti, Francesca; Brandi, Maria Luisa (2023). Oxidative Stress and Inflammation in Osteoporosis: Molecular Mechanisms Involved and the Relationship with microRNAs. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 0-0, ISSN:1422-0067 DOI

Donati, Simone; Marini, Francesca; Giusti, Francesca; Palmini, Gaia; Aurilia, Cinzia; Falsetti, Irene; Iantomasi, Teresa; Brandi, Maria Luisa (2023). Calcifediol: Why, When, How Much?. PHARMACEUTICALS, vol. 16, pp. 0-0, ISSN:1424-8247 DOI

Romagnoli, Cecilia; Zonefrati, Roberto; Lucattelli, Elena; Innocenti, Marco; Civinini, Roberto; Iantomasi, Teresa; Brandi, Maria Luisa (2023). In Vitro Effects of PTH (1-84) on Human Skeletal Muscle-Derived Satellite Cells. BIOMEDICINES, vol. 11, pp. 0-0, ISSN:2227-9059 DOI

Francesca Miglietta, Luca Iamartino, Gaia Palmini, Francesca Giusti, Francesca Marini, Teresa Iantomasi, Maria Luisa Brandi (2023). Endocrine sequelae of hematopoietic stem cell transplantation: Effects on mineral homeostasis and bone metabolism. FRONTIERS IN ENDOCRINOLOGY, pp. 0-0, ISSN:1664-2392

Francesco Tonelli, Francesca Marini, Francesca Giusti, Teresa Iantomasi, Francesco Giudici, Maria Luisa Brandi (2023). Pancreatic neuroendocrine tumors in MEN1 patients: difference in post-operative complications and tumor progression between major and minimal pancreatic surgeries. CANCERS, pp. 0-0, ISSN:2072-6694

Marini, Francesca; Giusti, Francesca; Marasco, Elena; Xumerle, Luciano; Kwiatkowska, Katarzyna Malgorzata; Garagnani, Paolo; Biver, Emmanuel; Ferrari, Serge; Iolascon, Giovanni; Iantomasi, Teresa; Brandi, Maria Luisa (2023). High frequency of heterozygous rare variants of the SLC34A1 and SLC9A3R1 genes in patients with atypical femur fracture. EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol. 188, pp. 0-0, ISSN:0804-4643 DOI

Guasti, Leonardo; Cianferotti, Luisella; Pampaloni, Barbara; Tonelli, Francesco; Martelli, Francesco; Iantomasi, Teresa; Brandi, Maria Luisa (2023). Evaluation of food and nutrient intake in a population of subjects affected by periodontal disease with different levels of bone mineral density. FRONTIERS IN ENDOCRINOLOGY, vol. 14, pp. 0-11, ISSN:1664-2392 DOI

Simone Ciuffi, Francesca Marini, Caterina Fossi, Simone Donati, Francesca Giusti, Annalisa Botta, Laura Masi, Giancarlo Isaia, Claudio Marcocci, Silvia Migliaccio, Salvatore Minisola, Ranuccio Nuti, Umberto Tarantino, Teresa Iantomasi, Maria Luisa Brandi (2022). Circulating MicroRNAs as Biomarkers of Osteoporosis and Fragility Fractures. THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, pp. 2267-2285, ISSN:0021-972X

Francesca Marini, Francesca Giusti, Teresa Iantomasi, Federica Cioppi, Maria Luisa Brandi (2022). Bone phenotypes in multiple endocrine neoplasia type 1: survey on the MEN1 Florentine database. ENDOCRINE CONNECTIONS, pp. 0-0, ISSN:2049-3614

Francesca Marini, Laura Masi, Francesca Giusti, Luisella Cianferotti, Federica Cioppi, Gemma Marcucci, Simone Ciuffi, Emmanuel Biver, Giuseppe Toro, Giovanni Iolascon, Teresa Iantomasi, and Maria Luisa Brandi (2022). ALPL genotypes in patients with atypical femur fractures or other biochemical and clinical signs of hypophosphatasia. THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, pp. e2087-e2094, ISSN:0021-972X

Maria Luisa Brandi , Stefania Bandinelli, Teresa Iantomasi, Francesca Giusti, Eleonora Talluri, Giovanna Sini, Fabrizio Nannipieri, Santina Battaglia, Riccardo Giusti, Colin Gerard Egan, Luigi Ferrucci (2022). Association between vitamin D and bisphenol A levels in an elderly Italian population: results from the InCHIANTI study. ENDOCRINE CONNECTIONS, pp. 1-11, ISSN:2049-3614

Simone Donati, Gaia Palmini, Cinzia Aurilia, Irene Falsetti, Francesca Miglietta, Teresa Iantomasi, Maria Luisa Brandi (2022). Rapid nontranscriptional effects of calcifediol and calcitriol. NUTRIENTS, pp. 1291-1302, ISSN:2072-6643

Domazetovic V.; Falsetti I.; Ciuffi S.; Iantomasi T.; Marcucci G.; Vincenzini M.T.; Brandi M.L. (2022). Effect of Oxidative Stress-Induced Apoptosis on Active FGF23 Levels in MLO-Y4 Cells: The Protective Role of 17-β-Estradiol. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 2103-2119, ISSN:1661-6596 DOI

Romagnoli, Cecilia; Iantomasi, Teresa; Brandi, Maria Luisa (2022). Impact of X-Linked Hypophosphatemia on Muscle Symptoms. GENES, vol. 13, pp. 0-0, ISSN:2073-4425 DOI

Palmini G.; Romagnoli C.; Donati S.; Zonefrati R.; Galli G.; Marini F.; Iantomasi T.; Aldinucci A.; Leoncini G.; Franchi A.; Beltrami G.; Campanacci D.A.; Capanna R.; Brandi M.L. (2021). Analysis of a preliminary microRNA expression signature in a human telangiectatic osteogenic sarcoma cancer cell line. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 1-27, ISSN:1661-6596 DOI

Aurilia C.; Donati S.; Palmini G.; Miglietta F.; Iantomasi T.; Brandi M.L. (2021). The involvement of long non-coding rnas in bone. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 3909-3939, ISSN:1661-6596 DOI

Donati S.; Palmini G.; Romagnoli C.; Aurilia C.; Miglietta F.; Falsetti I.; Marini F.; Zonefrati R.; Galli G.; Marcucci G.; Iantomasi T.; Brandi M.L. (2021). In vitro non-genomic effects of calcifediol on human preosteoblastic cells. NUTRIENTS, vol. 13, pp. 1-13, ISSN:2072-6643 DOI

Francesca Marini, Francesca Giusti, Teresa Iantomasi, and Maria Luisa Brandi (2021). Genetic Determinants of inherited endocrine tumors: do they have a direct role in bone metabolism regulation and osteoporosis?. GENES, pp. 1286-1305, ISSN:2073-4425

Donati S.; Aurilia C.; Palmini G.; Miglietta F.; Falsetti I.; Iantomasi T.; Brandi M.L. (2021). MicroRNAs as potential biomarkers in pituitary adenomas. NON-CODING RNA, vol. 7, pp. 55-76, ISSN:2311-553X DOI

Domazetovic V.; Falsetti I.; Viglianisi C.; Vasa K.; Aurilia C.; Stio M.; Menichetti S.; Iantomasi T. (2021). Protective role of natural and semi-synthetic tocopherols on TNFα-induced ros production and ICAM-1 and Cl-2 expression in ht29 intestinal epithelial cells. ANTIOXIDANTS, vol. 10, pp. 1-15, ISSN:2076-3921 DOI

Miglietta F.; Palmini G.; Giusti F.; Donati S.; Aurilia C.; Iantomasi T.; Brandi M.L. (2021). Hypoparathyroidism: State of the art on cell and tissue therapies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 10272-10286, ISSN:1661-6596 DOI

Marini F.; Giusti F.; Iantomasi T.; Brandi M.L. (2021). Parathyroid tumors: Molecular signatures. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 11206-11224, ISSN:1661-6596 DOI

Romagnoli C.; Iantomasi T.; Brandi M.L. (2021). Available in vitro models for human satellite cells from skeletal muscle. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 1-17, ISSN:1661-6596 DOI

Aurilia C.; Donati S.; Palmini G.; Miglietta F.; Falsetti I.; Iantomasi T.; Brandi M.L. (2021). Are non-coding rnas useful biomarkers in parathyroid tumorigenesis?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 10465-10479, ISSN:1661-6596 DOI

Marini F.; Giusti F.; Iantomasi T.; Brandi M.L. (2021). Congenital metabolic bone disorders as a cause of bone fragility. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 10281-10315, ISSN:1661-6596 DOI

Domazetovic V.; Marcucci G.; Falsetti I.; Bilia A.R.; Vincenzini M.T.; Brandi M.L.; Iantomasi T. (2020). Blueberry juice antioxidants protect osteogenic activity against oxidative stress and improve long-term activation of the mineralization process in human osteoblast-like saos-2 cells: Involvement of sirt1. ANTIOXIDANTS, vol. 9, pp. 1-20, ISSN:2076-3921 DOI Accesso ONLINE all'editore

Vladana Domazetovic, Teresa Iantomasi, Andrea Giovanni Bonanomi, Maria Stio (2020). Vitamin D regulates claudin-2 and claudin-4 expression in active ulcerative colitis by p- Stat-6 and Smad-7 signaling. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, pp. 1-14, ISSN:0179-1958 DOI

Domazetovic V, Marcucci G, Pierucci F, Bruno G, Di Cesare Mannelli L, Ghelardini C, Brandi ML, Iantomasi T, Meacci E, Vincenzini MT. (2019). Blueberry juice protects osteocytes and bone precursor cells against oxidative stress partly through SIRT1. FEBS OPEN BIO, vol. 9 (6), pp. 1082-1096, ISSN:2211-5463, Wiley Blackwell: DOI Accesso ONLINE all'editore

Vladana Domazetovic, Andrea Giovanni Bonanomi, Maria stio, Maria Teresa vincenzini, Teresa Iantomasi (2019). Resveratrol decreases TNFα-induced ICAM-1 expression and release by Sirt-1-independent mechanism in intestinal myofibroblasts. EXPERIMENTAL CELL RESEARCH, vol. 382, pp. 111479-111486, ISSN:0014-4827

Domazetovic V, Marcucci G, Iantomasi T, Brandi ML2, Vincenzini MT (2017). Oxidative stress in bone remodeling: role of antioxidants. CLINICAL CASES IN MINERAL AND BONE METABOLISM, vol. 14, pp. 209-216, ISSN:1724-8914 DOI

Fontani, Filippo; Domazetovic, Vladana; Marcucci, Tommaso; Vincenzini, Maria Teresa ; Iantomasi, Teresa (2017). MMPs, ADAMs and their natural inhibitors in inflammatory bowel disease: involvement of oxidative stress. JOURNAL OF CLINICAL GASTROENTEROLOGY AND TREATMENT, pp. 0-0, ISSN:2469-584X

Domazetovic, Vladana; Fontani, Filippo; Tanini, Damiano; D'Esopo, Veronica; Viglianisi, Caterina; Marcucci, Gemma; Panzella, Lucia; Napolitano, Alessandra; Brandi, Maria Luisa; Capperucci, Antonella; Menichetti, Stefano; Vincenzini, Maria Teresa; Iantomasi, Teresa (2017). Protective role of benzoselenophene derivatives of resveratrol on the induced oxidative stress in intestinal myofibroblasts and osteocytes. CHEMICO-BIOLOGICAL INTERACTIONS, vol. 275, pp. 13-21, ISSN:0009-2797 DOI Accesso ONLINE all'editore

Domazetovic, Vladana; Fontani, Filippo; Marcucci, Gemma; Iantomasi, Teresa; Brandi, Maria Luisa; Vincenzini, Maria Teresa (2017). Estrogen inhibits starvation-induced apoptosis in osteocytes by a redox-independent process involving association of JNK and glutathione S-transferase P1-1. FEBS OPEN BIO, vol. 7, pp. 0-0, ISSN:2211-5463 DOI Accesso ONLINE all'editore

Fontani, F; Domazetovic, V; Marcucci, T; Vincenzini, MT; Iantomasi, T (2016). Tumor necrosis factor-alpha up-regulates ICAM-1 expression and release in intestinal myofibroblasts by redox-dependent and -independent mechanisms. JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 370-381, ISSN:0730-2312 DOI

Fontani F; Marcucci G; Iantomasi T; Brandi ML; Vincenzini MT (2015). Glutathione, N-acetylcysteine and Lipoic Acid Down-Regulate Starvation-Induced Apoptosis, RANKL/OPG Ratio and Sclerostin in Osteocytes: Involvement of JNK and ERK1/2 Signalling.. CALCIFIED TISSUE INTERNATIONAL, pp. 335-346, ISSN:0171-967X

Domazetovic V, Fontani F, Marcucci G, Iantomasi T, Vincenzini MT. (2015). Estrogens down-regulate RANKL/OPG ratio and sclerostin levels in starvation-induced apoptosis in osteocytes.. In: 40th FEBS Congress, Berlin, Germany, Wiley-Blackwell, pp. 15-15.

F. Fontani; T. Marcucci; M.T. Vincenzini; T. Iantomasi (2014). Effect of NAC and Curcumin on the increase of MMP-3 induced by oxidative stress in intestinal myofibroblasts. In: FEBS- EMBO, Paris, 30 August-4 September, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, vol. 281, pp. 118-118.

Filippo Fontani; Tommaso marcucci; Lucia Picariello; Francesco Tonelli; Maria Teresa Vincenzini; Teresa iantomasi (2014). Redox regulation of MMP-3/TIMP-1 ratio in intestinal myofibroblasts: Effect of N-acetylcysteine and curcumin. EXPERIMENTAL CELL RESEARCH, pp. 77-86, ISSN:0014-4827

F. Fontani; G. Marcucci; T. Iantomasi; M.L. Brandi; M.T. Vincenzini (2014). Role of antioxidants on RANKL and OPG production in apoptotic osteocytes. In: FEBS-EMBO, Paris, 30 August-4 September, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, vol. 281, pp. 163-163.

F.Fontani; T. Marcucci; M. T. Vincenzini; T. Iantomasi (2013). Effect of N-acetylcysteine on the MMP-3/TIMP-1 ratio in intestnal subepithelial myofibroblasts of Crohn's disease patients. In: 38th FEBS Congress, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, vol. 280, pp. 555-556.

F. Fontani; G. Marcucci; T. Iantomasi; M.T. Vincenzini (2013). Role of GSH and estrogen on serum-starvation induced apoptosis in osteocytes. In: 38th FEBS Congress, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, pp. 562-563.

Cecilia Romagnoli; Tommaso Marcucci; Lucia Picariell; Francesco Tonelli ; Maria Teresa Vincenzini ; Teresa Iantomasi (2013). Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, vol. 28, pp. 915-924, ISSN:0179-1958

Romagnoli C; Marcucci G; Favilli F; Zonefrati R; Mavilia C; Galli G; Tanini A; Iantomasi T; Brandi ML; Vincenzini MT. (2013). Role of GSH/GSSG redox couple in osteogenic activity and osteoclastogenic markers of human osteoblast-like SaOS-2 cells.. THE FEBS JOURNAL, vol. 280, pp. 867-879, ISSN:1742-4658 DOI

C.Romagnoli;T.Marcucci;L.Picariello;M.T.Vincenzini;T.Iantomasi (2011). Role of GSH and oxidative state related on MMP-2 activity in intestinal myofibroblasts of Crohn's disease patients. In: 36th FEBS Congress, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, vol. 278, pp. 306-306.

C Romagnoli, G Marcucci, C Mavilia, G Galli, A Tanini, T Iantomasi, ML Brandi, MT Vincenzini (2011). Role of glutathione and oxidative state on markers genes involved in bone remodelling. In: 36th FEBS Congress, Seamus Martin, pp. 402-402.

C.Romagnoli;G.Marcucci;R.Zonefrati;C.Mavilia;G.Galli;A.Tanini;T.Iantomasi;M.T.Vincenzini;M.L.Brandi (2011). Glutathione role on specific markers of the bone remodeling. JOURNAL OF BONE AND MINERAL RESEARCH, pp. MO0226-MO0226, ISSN:1523-4681

C.Romagnoli;G.Marcucci;C.Mavilia;G.Galli;A.Tanini;T.Iantomasi;M.L.Brandi;M.T.Vincenzini (2011). Role of glutathione and oxidative state on marker genes involved in bone remodelling. In: 36th FEBS Congress, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, vol. 278, pp. 402-402.

Catarzi S; Favilli F; Romagnoli C; Marcucci T; Picariello L; Tonelli F; Vincenzini MT; Iantomasi T. (2011). Oxidative state and IL-6 production in intestinal myofibroblasts of Crohn's disease patients.. INFLAMMATORY BOWEL DISEASES, vol. 17, pp. 1674-1684, ISSN:1078-0998

Catarzi S; Romagnoli C; Marcucci G; Favilli F; Iantomasi T; Vincenzini MT. (2011). Redox regulation of ERK1/2 activation induced by sphingosine 1-phosphate in fibroblasts: involvement of NADPH oxidase and platelet-derived growth factor receptor.. BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1810, pp. 446-456, ISSN:0006-3002 DOI

G.Marcucci;C.Romagnoli;F.Favilli;I.Tognarini;R.Zonefrati;G.Galli;A.Tanini;T.Iantomasi;M.T.Vincenzini;M.L.Brandi (2010). Intracellular oxidative status and glutathione role on osteogenic activity of osteoblastic cells. In: IOF WCO-ECCE0 10, Firenze, John A. Kanis and Robert Lindsay, pp. S240-S240.

C.Romagnoli;G.Marcucci;R.Zonefrati;F.Favilli;S.Catarzi;T.Iantomasi;A.Tanini;M.L.Brandi;M.T.Vincenzini (2010). Redox regulation of osteogenic activity in osteoblastic cells. In: 35th FEBs Congress, Gothenburg, Sweden, 25 june-1 july, 2010, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, pp. 296-296.

S.Catarzi;F.Favilli;C.Romagnoli;T.Marcucci;L.Picariello;F.Tonelli;M.T.Vincenzini;T.Iantomasi (2010). Oxidative state and IL-6 production in intestinal myofibroblasts of Crohn's Dsease patients. In: 55° Congresso SIB, Milano, Francesco Malatesta (L'Aquila (It), pp. 96-96.

C.Romagnoli;F.Favilli;G.Marcucci;I.Tognarini;S.Sabina;S.Catarzi;T.Iantomasi;M.L.Brandi;M.T.Vincenzini (2009). Glutathione role on proliferation and differentiation processes of osteoblastic cells. In: 34th FEBS Congress, Prague, Czech Republic, 4-9 july 2009, vol. The Febs Journal, pp. 339-340.

C.Romagnoli;S.Catarzi;F.Favilli;S.Sorace;I.Tognarini;R.Zonefrati;T.Iantomasi;M.T.Vincenzini (2009). Intracellular oxidative status and osteogenic activity of SaOS-2 osteosarcoma cells.. In: 54° Congresso SIB, Catania, società italiana biochimica, pp. 192-192.

S.Catarzi;F.Favilli;T.Marcucci;F.Tonelli;M.T.Vincenzini;T.Iantomasi (2008). Relationship between intracellular oxidative status and interleukin synthesis in 18Co cells:involvement of p38 and ERK1/2 MAPkinases. In: 53rd National Meeting of the Italian society of Biochemistry and Molecular Biology and National Meeting of Chemistry of Biological Systems Italian Chemical Society, Riccione, 23-26 September, 2008, Firenze University Press, pp. 2.24-2.24, ISBN:9788884538208

S.Catarzi; T.Marcucci; L.Papucci; F.Favilli; M.Donnini; F.Tonelli; MT.Vincenzini; T.Iantomasi (2008). Apoptosis and Bax, Bcl-2, Mcl-1 expression in neutrophils of Crohn's disease. INFLAMMATORY BOWEL DISEASES, vol. 14, pp. 819-825, ISSN:1078-0998 DOI

S.CATARZI;F.FAVILLI;T.MARCUCCI;M.T.VINCENZINI;T.IANTOMASI (2007). GSH role in the synthesis of interleukins in intestinal subepithelial myofibroblasts. In: 52° Congresso SIB, Francesco Malatesta (L'Aquila (It), pp. 78-78.

S. Catarzi; E. Giannoni; F. Favilli; E. Meacci; T. Iantomasi; MT. Vincenzini (2007). Sphingosine 1-phosphate stimulation of NADPH oxidase activity: relationship with platelet-derived growth factor receptor and c-Src kinase. BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1770, pp. 872-883, ISSN:0006-3002 DOI

S.CATARZI;F.FAVILLI;T.IANTOMASI;M.T.VINCENZINI (2007). Role of PDGFr tyrosine kinase and c-Src kinase on the redox regulation of ERK activity induced by sphingosine1-phosphate in NIH3T3 fibroblasts. In: 52°Congresso SIB, Francesco Malatesta (L'Aquila (It), pp. 90-90.

T.Marcucci;S.Catarzi;F.Favilli;F.Tonelli;M.T.Vincenzini;T.Iantomasi (2006). Role of TNF-alpha and GM-CsF on apoptosis and adhesion in PMN of patients with Crohn's disease. In: XII national Congress of the Italian Federation of Digestive Diseases, Naples, Italy, 1-5 April, 2006, pp. S126-S126.

S.Catarzi;F.Favilli;M.Donnini;L.Papucci;T.Marcucci;F.Tonelli;M.T.Vincenzini;T.Iantomasi (2006). Bax/Bcl2 ratio regulates differently the apoptosis in ulcerative colitis and Crohn’s disease. In: 51° Congresso SIB, Riccione, Francesco Malatesta (L'Aquila, It), pp. 157-157.

C.BIAGIONI; F.FAVILLI; S.CATARZI; T.MARCUCCI; M.FAZI; F.TONELLI; MT.VINCENZINI;T.IANTOMASI (2006). Redox state and O2- production in neutrophils of Crohn's disease patients. EXPERIMENTAL BIOLOGY AND MEDICINE, vol. 231, pp. 186-195, ISSN:1535-3702

S.Catarzi;F.Favilli;C.Biagioni;T.Marcucci;F.Tonelli;T.Iantomasi;M.T.Vincenzini (2005). Relationship between ROS production and adhesion processes in neutrophils of patients with Crohn’s disease. In: 50°Congresso SIB, Riccione, Francesco Malatesta (L'Aquila (It), pp. 113-113.

S.CATARZI; C.BIAGIONI; E.GIANNONI; F.FAVILLI; T.MARCUCCI; T.IANTOMASI; MT.VINCENZINI (2005). Redox regulation of Platelet-Derived-Growth-Factor-Receptor: role of NADPH-oxidase and c-Src tyrosine kinase. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, vol. 1745, pp. 166-175, ISSN:0167-4889 DOI

S. CATARZI; C. BIAGIONI; F. FAVILLI; E. GIANNONI; T. IANTOMASI; M. VINCENZINI (2004). ROLE OF SPHINGOSINE 1-PHOSPHATE ON NDAPHOXIDASE ACTIVATION AND REDOX REGULATION OF C-SRC IN NIH3T3 FIBROBLASTS. In: 3RD SPHINGOLIPID CLUB MEETING, FIRENZE, pp. 31-31.

S. CATARZI; C. BIAGIONI; F. FAVILLI; E. GIANNONI; T. IANTOMASI; M. VINCENZINI (2004). ROLE OF PDGF AND S1P ON THE REDOX REGULATION OF C-SRC TYROSINE KINASE ACTIVITY. In: 49° CONGRESSO NAZIONALE SIB, RICCIONE, Francesco Malatesta (L'Aquila, It), pp. 93-93.

T. IANTOMASI; C. BIAGIONI; F. FAVILLI; S. CATARZI; M. VINCENZINI; F. TONELLI; M. PAROLI; T. MARCUCCI (2003). NADPH OXIDASE ACTIVITY AND RESPIRATORY BURST IN NEUTROPHILS OF CROHN'S DISEASE PATIENTS. In: 48° CONGRESSO NAZIONALE DELLA SOCIETÀ ITALIANA DI BIOCHIMICA, FERRARA, Francesco Malatesta (L'Aquila (It), pp. 2.04-2.04.

T.IANTOMASI; F.FAVILLI; S.CATARZI; E.GIANNONI; C.BIAGIONI; MT.VINCENZINI (2003). Involvement of tyrosine phosphorylation on GSH transport in NIH3T3 fibroblasts. IUBMB LIFE, vol. 55, pp. 159-165, ISSN:1521-6543 DOI

S. CATARZI; D. DEGL'INNOCENTI; T. IANTOMASI; F. FAVILLI; M. VINCENZINI (2002). THE ROLE OF H2O2 IN THE PLATELET-DERIVED GROWTH FACTOR-INDUCED TRANSCRIPTION OF THE GAMMA-GLUTAMYLCYSTEINE HEAVY SUBUNIT. CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 59, pp. 1388-1394, ISSN:1420-682X

T. IANTOMASI; F. FAVILLI; S. CATARZI; M. VINCENZINI (2001). GSH ROLE ON PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE PHOSPHORYLATION INDUCED BY H2O2. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 280, pp. 1279-1285, ISSN:0006-291X DOI

S. CATARZI; F. FAVILLI; T. IANTOMASI; M. VINCENZINI; A. FIUSCO (2001). GLUTATHIONE ROLE IN CELL CYCLE OF HUMAN NEUROBLASTOMA CELLS. In: 46° Congresso SIB, SIENA, pp. 153-153.

T.Iantomasi;F.Favilli;S.Catarzi;M.T.Vincenzini (2000). GSH role on PDGFr autophosphorylation obtained by its ligand or H2O2. In: 45° Congresso SIB, Napoli, pp. 198-198.

F. FAVILLI; S. CATARZI; T. IANTOMASI; M. VINCENZINI (2000). GLUTATHIONE TRANSPORT SYSTEM IN NIH3T3 FIBROBLASTS. MOLECULAR CELL BIOLOGY RESEARCH COMMUNICATIONS, vol. 4, pp. 212-218, ISSN:1522-4724 DOI

T.IANTOMASI; F.FAVILLI; MT.VINCENZINI (1999). Evidence of glutathione transporter in rat brain synaptosomal membrane vesicles.. NEUROCHEMISTRY INTERNATIONAL, vol. 34 (6), pp. 509-516, ISSN:0197-0186 DOI

A.Fiusco;F.Favilli;S.Catarzi;T.Iantomasi;M.T.Vincenzini (1999). Glutathione redox status and growth of human neuroblastoma cells. In: 44° Congresso SIB, Alghero, pp. 121-121.

T.Iantomasi;F.Favilli;E.Giannoni;M.T.Vincenzini (1999). Glutathione ATP-dependent transport in NIH3T3 fibroblasts: involvement of tyrosine phoshorilation mechanisms. In: 44° Congresso SIB, Alghero, Francesco Malatesta (L'Aquila (It), pp. 182-182.

CECCHI C; LATORRACA S; SORBI S; IANTOMASI T; FAVILLI F; M. VINCENZINI; LIGURI G (1999). Glutathione level is altered in lymphoblasts from patients with familial Alzheimer's disease. NEUROSCIENCE LETTERS, vol. 275 (2), pp. 152-154, ISSN:0304-3940 DOI

D.DEGL'INNOCENTI; F.ROSATI; T.IANTOMASI; G.RAMPONI; MT.VINCENZINI (1999). GSH-system in relation to redox state in dystrophic. BIOCHIMIE, vol. 81(11), pp. 1025-1029, ISSN:0300-9084 DOI

T.IANTOMASI; F.FAVILLI; D.DEGL'INNOCENTI; MT.VINCENZINI (1999). Increased glutathione synthesis associated with platelet-derived growth factor stimulation of NIH3T3 fibroblasts. BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1452, pp. 303-312, ISSN:0006-3002 DOI

D. DEGL'INNOCENTI; ROSATI F; IANTOMASI T; VINCENZINI MT; RAMPONI G (1999). GSH system in relation to redox state in dystrophic skin fibroblasts. BIOCHIMIE, vol. 81 (11), pp. 1025-1029, ISSN:0300-9084 Accesso ONLINE all'editore

D.Degl'Innocenti;F.Rosati;S.Catarzi;T.Iantomasi;M.T.Vincenzini (1999). PDGF-mediayed transcriptional regulation of gamma-glutamylcysteine synthetase (gamma-GCS) role of specific transduction factors. In: 44° Congresso SIB, Alghero, pp. 178-178.

F.Favilli;T.Iantomasi;M.T.Vincenzini (1998). Glutathione transport in NIH3T3 fibroblasts. In: 43° Congresso SIB, pp. 283-283.

T.IANTOMASI; F.FAVILLI, P.MARRACCINI, MT.VINCENZINI (1998). Glutathione involvement on the intestinal Na+-dependent D-glucose active transporter. MOLECULAR AND CELLULAR BIOCHEMISTRY, vol. 178, pp. 387-392, ISSN:0300-8177 DOI

S.LATORRACA;C.CECCHI;T.IANTOMASI;M.T.VINCENZINI;G.LIGURI;A.PIERI;L.AMADUCCI;S.SORBI; (1998). Glutathione levels in lymphoblasts from patients with familial Alzheimer's disease linked to presenilin genes. In: 50th Annual Meeting, American Academy of Neurology, Minneapolis, LIPPINCOTT WILLIAMS & WILKINS, 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 USA, vol. 50, pp. A314-A314.

S.RIGACCI; T.IANTOMASI; P.MARRACCINI; A.BERTI; MT.VINCENZINI; G.RAMPONI (1997). Evidence for glutathione involvement in platelet-derived growth-factor-mediated signal transduction. BIOCHEMICAL JOURNAL, vol. 324, pp. 791-796, ISSN:0264-6021

T.Iantomasi; F.Favilli; P.Marraccini; MT.Vincenzini (1997). Effect of orally administered glutathione levels in some organs of rats: role of specific transporters. BRITISH JOURNAL OF NUTRITION, vol. 78(2), pp. 293-300, ISSN:0007-1145 DOI

C.CECCHI;T.IANTOMASI;S.LATORRACA;F.FAVILLI; M.T.VINCENZINI; G.LIGURI; A.PIERI;S.SORBI;G.RAMPONI (1997). Glutathione levels in Alzheimer's disease lymphoblasts. In: 42° Congresso SIB, Ancona, pp. 300-300.

M.T.VINCENZINI;F.FAVILLI;P.MARRACCINI;T.IANTOMASI (1997). Effect of Platelet-derived growth factor on glutathione content in NIH3T3 mouse fibroblasts. In: 17th International Congress of Biochemistry and Molecular Biology, San Francisco, California, pp. A1162-A1162.

T.IANTOMASI; F.FAVILLI; P.MARRACCINI; T.MAGALDI; P.BRUNI; MT.VINCENZINI (1997). Glutathione transport system in human small intestine epithelial cells. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 1330 (2), pp. 274-283, ISSN:0925-4439

C.CECCHI;T.IANTOMASI;S.LATORRACA;F.FAVILLI; M.T.VINCENZINI; G.LIGURI; A.PIERI;S.SORBI;G.RAMPONI (1997). Presenilin Alzheimer's disease lymphoblasts show lowere glutathione. In: Biomedicina'97 Meeting on Molecular Medicine, pp. 168-168.

A.Berti; T.Iantomasi; P.Marraccini; S.Rigacci; M.T.Vincenzini (1996). Glutathione and cell proliferation:relation with platelet-derived growth factor receptor. In: SIB 1996, Catania, 18-21/9/1996, pp. 200-200.

A.BERTI;T.IANTOMASI;P.MARRACCINI;S.RIGACCI;M.T.VINCENZINI (1996). Glutathione and cell proliferation: relation with platelet-derived growth factor receptor. In: 41° Congresso SIB, Catania, pp. 200-200.

T.IANTOMASI;F.FAVILLI;P.MARRACCINI;P.BRUNI;M.T.VINCENZINI; (1995). Glutathione transport system in human intestinal epithelial cells. In: 40° Congresso SIB, pp. P-132-P-132.

P.Marraccini; T.Iantomasi; S.Rigacci; S.Pacini; M.Ruggiero; M.T.Vincenzini; G.Ramponi (1994). Effect of phosphotyrosine phosphatase over-expression on glutathione metabolism in normal and oncogene-transformed cells. FEBS LETTERS, vol. 344, pp. 157-160, ISSN:0014-5793

T.IANTOMASI;P.MARRACCINI;F.FAVILLI;M.T.VINCENZINI (1994). A possible role of the glutathione on the intestinal D-Glucose cotransporter. In: 39° Congresso SIB, Pavia, pp. 197-197.

F. FAVILLI; T. IANTOMASI; P. MARRACCINI; M. STIO; B. LUNGHI; C. TREVES; M.T. VINCENZINI (1994). Relationship between age and GSH metabolism in synaptosomes of rat cerebral cortex. NEUROBIOLOGY OF AGING, vol. 15, pp. 429-433, ISSN:0197-4580 DOI

M. STIO; T. IANTOMASI; F. FAVILLI; P. MARRACCINI; B. LUNGHI; M.T. VINCENZINI; C. TREVES (1994). Glutathione metabolism in heart and liver of the aging rat. BIOCHEMISTRY AND CELL BIOLOGY, vol. 72, pp. 58-61, ISSN:0829-8211

T.IANTOMASI, P.MARRACCINI, F.FAVILLI, MT.VINCENZINI; P.FERRETTI, F.TONELLI (1994). Glutathione metabolism in Crohn’s disease. BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY, vol. 53 (2), pp. 87-91, ISSN:0885-4505 DOI

IANTOMASI T; MARCUCCI P; FAVILLI F; VINCENZINI MT; FERRETTI P; F. TONELLI (1994). Glutathione metabolism in Crohn's disease.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 53, pp. 87-91, ISSN:0006-291X, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445:

M. STIO; B. LUNGHI; T. IANTOMASI; M.T. VINCENZINI; C. TREVES (1994). Effect of vitamin D deficiency and 1,25-dihydroxyvitamin D3 on rat heart metabolism. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 26, pp. 1421-1428, ISSN:0022-2828 DOI

S. PACINI; M. VINCENZINI; P. MARRACCINI; T. IANTOMASI; M. SANTUCCI; F. CASAMASSIMA; M. RUGGIERO (1994). Molecular Mechanisms responsible for radioresistance in cells transformed by oncogenes involved in lung cancer. In: G. Motta. LUNG CANCER FRONTIERS IN SCIENCE AND TREATMENT, pp. 195-200, Genova: GRAFICA L. P..

M.T.VINCENZINI;P.MARRACCINI;T.IANTOMASI;S.RIGACCI;S.PACINI;G.RAUGEI;M.RUGGIERO;G.RAMPONI (1993). Glutathione metabolism and overexpression of synthetic phosphotyrosine protein phosphate gene in normal and transformed cells. In: 38° Congresso SIB, Trieste, pp. 214-214.

M.T.VINCENZINI;F.FAVILLI;P.MARRACCINI;T.IANTOMASI (1993). GSH metabolism in Crohn’s disease. In: IV International Symposium on Inflammatory Bowel Diseases, Strasbourg (France), pp. 107-107.

T. IANTOMASI; F. FAVILLI; P. MARRACCINI; M. STIO; C. TREVES; A. QUATTRONE; S. CAPACCIOLI; M.T. VINCENZINI (1993). Age and GSH metabolism in rat cerebral cortex, as related to oxidative and energy parameters. MECHANISMS OF AGEING AND DEVELOPMENT, vol. 70, pp. 65-82, ISSN:0047-6374 DOI

M. STIO; B. LUNGHI; T. IANTOMASI; M.T. VINCENZINI; C. TREVES (1993). Effect of vitamin D deficiency and 1,25-dihydroxyvitamin D3 on metabolism and D-glucose transport in rat cerebral cortex. JOURNAL OF NEUROSCIENCE RESEARCH, vol. 35, pp. 559-566, ISSN:0360-4012 DOI

M. VINCENZINI; P. MARRACCINI; T. IANTOMASI; F. FAVILLI; S. PACINI; M. RUGGIERO (1993). ALTERED METABOLISM OF GLUTATHIONE IN CELLS TRANSFORMED BY ONCOGENES WHICH CAUSE RESISTANCE TO IONIZING RADIATIONS.. FEBS LETTERS, vol. 320(3), pp. 219-223, ISSN:0014-5793 DOI

Marraccini P.; Iantomasi T.; Rigacci S.; Pacini S.; Raugei G.; Ruggiero M.; Vincenzini M.T.; Ramponi G. (1993). Glutathione metabolism in normal and transformed cells. Effect of synthetic phosphotyrosine proteinphosphatase gene overexpression. In: IV Congress on University and Biotechnology Innovation, Firenze, ..., pp. 126-126.

MT.VINCENZINI; F.FAVILLI; T.IANTOMASI (1992). Intestinal uptake and transmembrane transport systems of intact GSH: characteristics and possible biological role. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 1113 (1), pp. 13-23, ISSN:0925-4439 DOI

M.STIO; T.IANTOMASI; F.FAVILLI; MT. VINCENZINI; C.TREVES (1992). Effect of a rickets-inducing diet and vitamin D metabolites [25-OH-D3 and 1,25(OH)2D3] on transmembrane transport systems in rat kidney. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, vol. 3, pp. 104-112, ISSN:0955-2863 DOI

F.FAVILLI;T.IANTOMASI;P.MARRACCINI;M.STIO;C.TREVES;M.T.VINCENZINI (1992). Relationship between glutathione system and oxidative-energetic metabolism during growth and aging in rat cerebral cortex. In: 21St ANNUAL MEETING FEBS, Dublin, pp. Th-65-Th-65.

M.T.VINCENZINI;F.FAVILLI;P.MARRACCINI;M.STIO;T.IANTOMASI (1992). Glutathione transport into plasma membrane vesicles from rat brain synaptosomes. In: 37° Congresso SIB, Perugia, pp. 215-215.

M.STIO;B.LUNGHI;T.IANTOMASI;M.T.VINCENZINI;C.TREVES (1992). Effect of vitamin D deficiency and 1,25(OH)2D3 on metabolism and D-glucose transport in rat brain. In: 21ST ANNUAL MEETING FEBS, Dublin, pp. Th-66-Th-66.

T.IANTOMASI;M.STIO;F.FAVILLI;P.MARRACCINI;C.TREVES;M.T.VINCENZINI (1991). Influence of aging on glutathione dependent-enzyme in the cerebral cortex and synaptosomes. In: International Conference on Protein Modification in Signal Transduction and Aging, Marciana Marina, pp. 75-75.

MT.Vincenzini; F.Favilli; M.Stio; T.Iantomasi (1991). Intestinal glutathione transport system: a possible detoxication role. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 1073 (3), pp. 571-579, ISSN:0925-4439 DOI

M. STIO; T. IANTOMASI; P. MARRACCINI; M.T. VINCENZINI; C. TREVES (1991). Effect of vitamin D deficiency on D-glucose and citrate transport in rat renal basolateral membrane vesicles. BIOCHEMISTRY INTERNATIONAL, vol. 24, pp. 1155-1163, ISSN:0158-5231

M.T.VINCENZINI;M.STIO;F.FAVILLI;T.IANTOMASI (1990). Intestinal glutathione transport system: characterstics and possible biological role. In: 35° Congresso SIB, Bari, pp. 54-54.

C.TREVES;M.STIO;T.IANTOMASI;F.FAVILLI;M.T.VINCENZINI (1990). D-glucose and citrate transport in renal basolateral membrane vesicles of rachitic rats. In: 20th Meeting FEBS, Budapest , Hungary, pp. 291-291.

C. TREVES; F. FAVILLI; M. STIO; T. IANTOMASI; M.T. VINCENZINI (1990). Changes in metabolite transport by small intestine and kidney of young and old rats. MECHANISMS OF AGEING AND DEVELOPMENT, vol. 52, pp. 263-276, ISSN:0047-6374 DOI

M.T.VINCENZINI;T.IANTOMASI;M.STIO;F.FAVILLI; (1990). Intestinal glutathione transport system: a possible detoxification role. In: 20th Meeting FEBS, Budapest, Hungary, pp. 291-291.

MT.VINCENZINI; T.IANTOMASI; F.FAVILLI (1989). Glutathione transport across intestinal brush-border membranes: effect of ions pH, ΔΨ, and inhibitors. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 987(1), pp. 29-37, ISSN:0925-4439 DOI

T. Iantomasi; E. Giachetti; P. Vanni; R. Tedesco; A. Cattaneo; F. Bardazzi; E. Ogier; C. Livi; G. Scarselli (1989). Enzymes of human cervical mucus: a comparative study on fertile and infertile mucus and on the endocervical epithelium. ACTA EUROPAEA FERTILITATIS, vol. 20, pp. 151-155, ISSN:0587-2421

M.T. VINCENZINI; T. IANTOMASI; M. STIO; F. FAVILLI; P. VANNI; F. TONELLI; C. TREVES (1989). Glucose transport during ageing by human intestinal brush-border membrane vesicles. MECHANISMS OF AGEING AND DEVELOPMENT, vol. 48, pp. 33-41, ISSN:0047-6374

C.TREVES;M.STIO;T.IANTOMASI;F.FAVILLI;M.T.VINCENZINI (1989). Effect of 1,25(OH)2D3 administration to rachitic rats on Na+ dependent D-glucose and citrate transport. In: 19th Meeting FEBS, ROMA, pp. TU392-TU392.

MT VINCENZINI; F FAVILLI; T IANTOMASI (1988). Glutathione mediated transport across intestinal brush-border membranes. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 942 (1), pp. 107-114, ISSN:0925-4439 DOI

C.TREVES;F.FAVILLI;M.STIO;T.IANTOMASI;M.T.VINCENZINI (1988). Effect of rickets and 25-OH-D3 on metabolite transport by the brush-border membrane of rat kideny.. In: 14th International congress of biochemistry, Praga, pp. 94-94.

C.TREVES;M.STIO;T.IANTOMASI;F.FAVILLI;M.T.VINCENZINI (1988). Sistemi di trasporto transmembrana di metaboliti durante l'invecchiamento. In: 34° Congresso SIB, Padova, pp. 364-364.

C. TREVES; F. FAVILLI; M. STIO; T. IANTOMASI; M.T. VINCENZINI (1988). Effect of 25-hydroxyvitamin D3 on Na+-dependent D-glucose transport in rachitic rats. BIOCHEMISTRY INTERNATIONAL, vol. 17, pp. 287-301, ISSN:0158-5231

M.T.VINCENZINI;F.FAVILLI;T.IANTOMASI (1988). Sistemi di trasporto transmembrana del glutatione: effetto di ioni, pH, Deltapsi, inibitori. In: 34° congresso SIB, Padova, pp. 366-366.

C. TREVES; F. FAVILLI; T. IANTOMASI; M. STIO; P. VANNI; M.T. VINCENZINI (1987). D-glucose uptake in intestinal brush-border membrane vesicles of rachitic rats. BIOCHEMISTRY INTERNATIONAL, vol. 14, pp. 1121-1132, ISSN:0158-5231

M.T.VINCENZINI;F.FAVILLI;T.IANTOMASI;P.VANNI (1987). Trasporto del glutatione in membrane di brush-border intestinali. In: 33° Congresso SIB, Brescia-Gardone Riviera, pp. A26-A26.

C.TREVES;F.FAVILLI;M.STIO;T.IANTOMASI;M.T.VINCENZINI (1987). Effect of 25-OH-D3 on D-glucose transport in rachitic rats. In: 18th FEBS MEETING, Ljubljana-Yugoslavia, pp. 169-169.

M.T. VINCENZINI; T. IANTOMASI; M. STIO; C. TREVES; F. FAVILLI; P. VANNI (1987). 1-O-n-octyl-beta-D-glucopyranoside as a competitive inhibitor of Na+-dependent D-glucose cotransporter in the small intestine brush-border membrane. BIOCHIMICA ET BIOPHYSICA ACTA, vol. 903, pp. 273-276, ISSN:0006-3002 DOI

M.T.VINCENZINI;F.FAVILLI;M.STIO;T.IANTOMASI;P.VANNI;C.TREVES (1986). Trasporto transmembrana del D-glucosio: effetto della carenza di vitamina D e di una dieta squilibrata Ca/P. In: 32° Congresso SIB, pp. 251-251.

F.FAVILLI;M.STIO;T.IANTOMASI;C.TREVES;M.T.VINCENZINI;P.VANNI (1986). Il beta-D-octilglucopiranoside, inibitore competitivo del cotrasportatore intestinale Na+ dipendente del D-glucosio. In: 32° Congresso SIB, Messina, pp. 257-257.

C. TREVES; M.T. VINCENZINI; P. VANNI; T. IANTOMASI; M. STIO; V. BACCARI (1986). Activities of NAD-and NADP-specific isocitrate dehydrogenases in kidney mitochondria of rachitic rat. BIOCHEMISTRY AND CELL BIOLOGY, vol. 64, pp. 1310-1316, ISSN:0829-8211

C.TREVES;M.T.VINCENZINI;L.FABIANI;T.IANTOMASI;M.STIO;V.BACCARI (1985). Influence of a rickets-inducing diet on kidney and liver metabolism. In: 13th International congress of Biochemistry, Amsterdam, pp. 333-333.

M.T.VINCENZINI;P.VANNI;M.STIO;T.IANTOMASI;F.FAVILLI;C.TREVES (1985). Molecole anfifiliche e trasporto transmembrana di glucosio. In: 31° Congresso SIB, Rimini, pp. 245-245.

F.FAVILLI;L.FABIANI;T.IANTOMASI;G.DINI;M.T.VINCENZINI;P.VANNI;C.TREVES (1984). Interazione di detergenti con enzimi di membrana e sistemi di trasporto in vescicole intestinali di mammifero. In: 30° Congresso SIB, Lacco Ameno d'Ischia, pp. 165-165.

Teresa IANTOMASI

Curriculum

1978       Graduated from High School;
1983   Graduation from Biological Sciences, at the University of Florence, discussing an experimental thesis in Biochemistry entitled “Action of detergents on the hydrolitc enzymes”;
1983-1984   Postgraduate at the Institute of Biological Chemistry and Obstetric and Gynaecological Clinical Hospital II in the University of Florence;
1983-1988    Volunteer Research at the Institute of Biological Chemistry, turned to Department of Biochemical Sciences;
1988        Scholarship for the Research Doctorate in Biochemistry at the University of Florence;
1990   Technical collaborator at the Department of Biochemical Sciences of University of Florence;
1993        PhD in Biochemistry, University of Florence;
1998 to present   Researcher (scientific disciplinary area BIO10) of Pharmacia Faculty at the Department of Biochemical Sciences of University of Florence;
2005-2010        Member of the self-assessment Group (GAV) for preparing the self-evaluation Report (RAV) for the degree course in Environmental Toxicology of the Faculty of Pharmacy, University of Florence;
2013 to present Member of the teaching committee for the undergraduate course in Chemistry and Pharmaceutical Technology (CTF) University of Florence

TEACHING ACTIVITY
•   From 1983 to 1988, as expert for Chemistry and Introductory Biochemistry and Biology and General Zoology of Degree Course in Medicine and Surgery, she took part in the evaluating committees and she has carried out tutoring activity. She has also held practical and theoretical training and seminaries for Biological Chemistry of the Degree Course in Medicine and Surgery;
•   From 1992 to 1998 she planned and managed several scientific practices and seminars and she has been a member of the evaluating committees for Applied Biochemistry and Biological Chemistry for the Degree Course in Pharmaceutical Chemistry and Technology (CTF), University of Florence;
•   From 1998 until 2017 she gives lessons in Biochemical Methods for the school of specialization in Clinical Chemistry and Biochemistry, Faculty of Medicine and Surgery;
•   From 1998 to 1999 and from 2011 to 2012 she has a teaching module of 10 hours in Biochemistry at Degree Course in CTF, Faculty of Pharmacy, University of Florence;
•   From 1998 to 2001 she has a teaching module of 30 hours in Applied Biochemistry at Degree Course of CTF, Faculty of Pharmacy, University of Florence;
•   From 2001 to present she is Regular Teacher of Applied Biochemistry at Degree Course in CTF, Faculty of Pharmacy, University of Florence;
•   From 2004 to 2005 and from 2008 to 2009 she has a teaching module of 8 hours in Biochemistry at the Degree Course in Environmental Toxicology, Faculty of Pharmacy, University of Florence;
•   2009-2010 she planned and managed the teaching activity of the Laboratory of Biology and Microbiology (Module Biomolecular Methods I), at the Degree Course in Biotechnology (Interfaculty);
•   From 2012 to 2019 she has become a member of the academic group of the PhD Course "Biochemistry and Molecular Biology", University of Siena.

She has been and is still now a Scientific Supervisor for many students and has followed and follows several students during the preparation of their graduation thesis. Moreover, for some students she has been and she is reporter or co- reporter.

RESEARCH ACTIVITY
She collaborated in several Research Projects with Prof. Francesco Tonelli (as Principal Investigator; PI) and to those with Prof. Maria Teresa Vincenzini (as Principle Investigator, PI) funded by Fondazione Ente Cassa di Risparmio (FCRF), Firenze.

She has participated, as member of the Research Unit (Scientific Responsible Prof. Maria Teresa Vincenzini), in the PRIN project funded in 1998 entitled "Glutathione and membrane receptor activity in relation to the intracellular redox state".

She has been a member of the Research Unit of Prof. Francesco Tonelli in Research Project PRIN 2007, considered fundable but not funded by MIUR due to lack of funds, entitled "Characterization of the inflammatory response in vitro of intestinal myofibroblasts in patients with chronic inflammatory bowel diseases (IBD): influence of estrogenic receptor expression of arg381gln gene polymorphism and il23r allelic variants card15/nod2 gene".

On November 1, 2020 she becomes scientific head of the Research Unit of the PRIN 2017 project (Scientific Coordinator Prof.ssa Giovanna Mantovani) Title: Physiopathology, Epidemiology and Genetics of primary pArathyroid hormone deficiency and reSistance: a mUlticenter italian Study (PEGASUS).

On November 1, 2020, she is responsible
Scientific of the Research Unit and Laboratory "Laboratory for the Study of Endocrine Tumors, Mineral Metabolic Diseases, Musculoskeletal Pain and Redox Regulated Mechanisms" of the Biochemistry Section of the Department of Science of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence.
Laboratory that carries out its scientific activity in the field of
the metabolic effects of vitamin D and its derivatives, the pathogenesis of parathyroid pathogenesis of parathyroid diseases, MEN1 and MEN2, redox regulation of biological biology of bone, pathologies of the musculoskeletal system, and diseases of the musculoskeletal system, the cell biology of muscle tissue and the cannabinoids and their biological effects.

She has participated and participates as member/president of committees for the recruitment of fellows for some of which she was and is the scientific responsible.

Principal research activities:

•   In vivo vivostudies on metabolic differences and effects of Vitamin D and its derivatives [25 OH D3 e 1,25 (O H)2D3] on the trans-membrane transport systems of metabolites, such as glucose, citrate, aminoacids, in organs of rats fed with a rachitogenic diet;
•   In vivo studies on the influence of aging on the activity of the glucose transport Na+-dependent system in brush-border membranes of the human intestine and of intestinal and renal brush-border of rat;
•   In vivo studies on the the antioxidant biological role of glutathione (GSH), related enzymes and the process of cerebral aging in cortex and synaptosomes of rat brain;
•   In vitro studies to find and to characterize a specific trans-membrane transport systems of GSH and its derivatives in intestinal brush-border, in synaptosome membranes of cerebral cortex of rat, in embryonic intestinal human cells (I407) and in murine fibroblasts (NIH3T3).
•   In vitro studies on the relationship among the GSH metabolism, oncogenic transformation and drug-radio resistance;
•   In vitro studies on the molecular mechanisms which are involved in the pathology of inflammatory bowel disease, related to ROS production, adhesion, apoptosis, cytokine synthesis and fibrosis;
•   In vitro Studies on the redox regulation of biological processes;
•   In vitro Studies on the role of oxidative stress and reductants in osteogenic activity of osteoblasts and osteocytes and in bone remodelling;
•   In vitro studies on the molecular mechanisms and molecular targets (i.e. non-coding RNA), which are at the base of several bone metabolism diseases.

The research activity is also well documented by several international publications and by participations in national and international scientific meetings.