Personale

Recapiti

Orario di ricevimento

Italiano

Curriculum

Pubblicazioni

Insegnamenti

Paola CHIARUGI

Ruolo attuale:: Professore Ordinario
SSD:: BIOS-07/A - Biochimica
Afferenza organizzativa:: Dipartimento di Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'

Recapiti

	0552751247
	paola.chiarugi(AT)unifi.it

Paola CHIARUGI

Curriculum

Paola Chiarugi nasce a Firenze il 5 settembre 1965.

1989- si laurea in Scienze Biologiche presso l' Università degli Studi di Firenze il 12 dicembre con la votazione di 110 /110 e lode e menzione di encomio della commissione di laurea, presso il Dipartimento di Biologia Animale e Genetica.
1890- Abilitazione alla professione di Biologo
1996- ottiene il titolo di Dottore di Ricerca in Biochimica
2000- ottiene il titolo di Specialista in Biochimica e Chimica Clinica.
1998- il 31 Agosto prende servizio come ricercatore nel settore disciplinare BIO11 (Biologia Molecolare) presso il Dipartimento di Scienze Biochimiche dell’Universita’ di Firenze, Facolta’ di Medicina e Chirurgia
2001- il 01/11/2001 la dott. Paola Chiarugi prende servizio come Professore Associato nel settore scientifico disciplinare BIO10 (Biochimica) presso il Dipartimento di Scienze Biochimiche dell’ Universita’ di Firenze, Facolta’ di Medicina e Chirurgia.
2005- il 01/11/05 prende servizio come Professore Ordinario nel settore scientifico disciplinare BIO10 (Biochimica) presso il Dipartimento di Scienze Biochimiche dell’Universita’ di Firenze, Facolta’ di Medicina e Chirurgia

POSIZIONE ATTUALE: Paola Chiarugi e’ attualmente professore straordinario di Biochimica presso il Dipartimento di Scienze Biochimiche dell’Universita’ di Firenze, Facolta’ di Medicina e Chirurgia. E’ membro del centro di Eccellenza per la ricerca scientifica DENOTHE’, del sistema internazionale di valutazione della ricerca scientifica in campo biologico “Faculty of 1000” e della Societa’ Italiana di Biochimica e Biologia Molecolare.

DIDATTICA: La prof. Chiarugi e’ titolare dal 1998 del corso integrato di Biochimica e Biologia Molecolare presso la Facolta’ di Medicina e Chirurgia. Inoltre dal 2002 e’ titolare del corso di Biochimica al corso di laurea triennale in Biotecnologie e di 2 corsi al biennio specialistico in Biotecnologie Mediche (Biochimica Cellulare e Metodi Generali e Speciali di Colture Cellulari).

Paola CHIARUGI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

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Tesi di Dottorato

Pranzini, Erica; Ippolito, Luigi; Pardella, Elisa; Giannoni, Elisa; Chiarugi, Paola (2024). Adapt and shape: metabolic features within the metastatic niche. TRENDS IN ENDOCRINOLOGY AND METABOLISM, pp. 0-0, ISSN:1043-2760 DOI

Ippolito, Luigi; Duatti, Assia; Iozzo, Marta; Comito, Giuseppina; Pardella, Elisa; Lorito, Nicla; Bacci, Marina; Pranzini, Erica; Santi, Alice; Sandrini, Giada; Catapano, Carlo V; Serni, Sergio; Spatafora, Pietro; Morandi, Andrea; Giannoni, Elisa; Chiarugi, Paola (2024). Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer. EMBO REPORTS, pp. 0-0, ISSN:1469-3178 DOI

Bacci, Marina; Lorito, Nicla; Smiriglia, Alfredo; Subbiani, Angela; Bonechi, Francesca; Comito, Giuseppina; Morriset, Ludivine; El Botty, Rania; Benelli, Matteo; López-Velazco, Joanna I; Caffarel, Maria M; Urruticoechea, Ander; Sflomos, George; Malorni, Luca; Corsini, Michela; Ippolito, Luigi; Giannoni, Elisa; Meattini, Icro; Matafora, Vittoria; Havas, Kristina; Bachi, Angela; Chiarugi, Paola; Marangoni, Elisabetta; Morandi, Andrea (2024). Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER+ breast cancer. SCIENCE TRANSLATIONAL MEDICINE, vol. 16, pp. 0-0, ISSN:1946-6242 DOI

Lorito, Nicla; Subbiani, Angela; Smiriglia, Alfredo; Bacci, Marina; Bonechi, Francesca; Tronci, Laura; Romano, Elisabetta; Corrado, Alessia; Longo, Dario Livio; Iozzo, Marta; Ippolito, Luigi; Comito, Giuseppina; Giannoni, Elisa; Meattini, Icro; Avgustinova, Alexandra; Chiarugi, Paola; Bachi, Angela; Morandi, Andrea (2024). FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer. EMBO MOLECULAR MEDICINE, pp. 0-0, ISSN:1757-4684 DOI

Anastasia Chillà, Cecilia Anceschi, Elena Frediani, Francesca Scavone, Tommaso Del Rosso, Giuseppe Pelagio, Antonio Tufaro, Giuseppe De Palma, Mario Del Rosso, Gabriella Fibbi, Paola Chiarugi, Anna Laurenzana, Francesca Margheri (2023). Inhibition of MMPs supports amoeboid angiogenesis hampering VEGF-targeted therapies via MLC and ERK 1/2 signaling. JOURNAL OF TRANSLATIONAL MEDICINE, pp. 102-116, ISSN:1479-5876 DOI

Ippolito, Luigi; Comito, Giuseppina; Parri, Matteo; Iozzo, Marta; Duatti, Assia; Virgilio, Francesca; Lorito, Nicla; Bacci, Marina; Pardella, Elisa; Sandrini, Giada; Bianchini, Francesca; Damiano, Roberta; Ferrone, Lavinia; la Marca, Giancarlo; Serni, Sergio; Spatafora, Pietro; Catapano, Carlo V; Morandi, Andrea; Giannoni, Elisa; Chiarugi, Paola (2022). Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer. CANCER RESEARCH, pp. canres.0914.2021-canres.0914.2021, ISSN:0008-5472 DOI

Elisa Pardella, Luigi Ippolito, Elisa Giannoni, Paola Chiarugi (2022). Nutritional and metabolic signalling through GPCRs. FEBS LETTERS, vol. 596, pp. 2364-2381, ISSN:0014-5793 DOI

Erica Pranzini, Elisa Pardella, Livio Muccillo, Angela Leo, Ilaria Nesi, Alice Santi, Matteo Parri, Tong Zhang, Alejandro Huerta Uribe, Tiziano Lottini, Lina Sabatino, Anna Caselli, Annarosa Arcangeli, Giovanni Raugei, Vittorio Colantuoni, Paolo Cirri, Paola Chiarugi, Oliver D.K. Maddocks, Paolo Paoli, Maria Letizia Taddei (2022). SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis. CELL REPORTS, vol. Volume 40, pp. 1-28, ISSN:2211-1247 DOI Accesso ONLINE all'editore

Iozzo M.; Sgrignani G.; Comito G.; Chiarugi P.; Giannoni E. (2021). Endocannabinoid system and tumour microenvironment: New intertwined connections for anticancer approaches. CELLS, vol. 10, pp. 3396-3430, ISSN:2073-4409 DOI

Leo A.; Pranzini E.; Pietrovito L.; Pardella E.; Parri M.; Cirri P.; Bruno G.; Calvani M.; Peppicelli S.; Torre E.; Sasaki M.; Yang L.; Zhu L.; Chiarugi P.; Raugei G.; Arbiser J.L.; Taddei M.L. (2021). Claisened hexafluoro inhibits metastatic spreading of amoeboid melanoma cells. CANCERS, vol. 13, pp. 3551-3573, ISSN:2072-6694 DOI

Bianchi, F; Dama, E; Di Nicolantonio, F; Baldassarre, G; Guerriero, I; Torchiaro, E; Bruno, A; Blandino, G; Allavena, P; Chiarugi, P; Sozzi, G; D'Incalci, M; Normanno, N (2021). COVID-19 epidemic strongly affected cancer research in Italy: a survey of the Italian Cancer Society (SIC). ESMO OPEN, vol. 6, pp. 1-8, ISSN:2059-7029 DOI

Mancini, Monica; Grasso, Margherita; Muccillo, Livio; Babbio, Federica; Precazzini, Francesca; Castiglioni, Ilaria; Zanetti, Valentina; Rizzo, Francesca; Pistore, Christian; De Marino, Maria Giovanna; Zocchi, Michele; Del Vescovo, Valerio; Licursi, Valerio; Giurato, Giorgio; Weisz, Alessandro; Chiarugi, Paola; Sabatino, Lina; Denti, Michela Alessandra; Bonapace, Ian Marc (2021). DNMT3A epigenetically regulates key microRNAs involved in epithelial-to-mesenchymal transition in prostate cancer. CARCINOGENESIS, vol. 42, pp. 1449-1460, ISSN:1460-2180 DOI

Raggi, Chiara; Taddei, Maria Letizia; Sacco, Elena; Navari, Nadia; Correnti, Margherita; Piombanti, Benedetta; Pastore, Mirella; Campani, Claudia; Pranzini, Erica; Iorio, Jessica; Lori, Giulia; Lottini, Tiziano; Peano, Clelia; Cibella, Javier; Lewinska, Monika; Andersen, Jesper B; di Tommaso, Luca; Vigano, Luca; Di Maira, Giovanni; Madiai, Stefania; Ramazzotti, Matteo; Orlandi, Ivan; Arcangeli, Annarosa; Chiarugi, Paola; Marra, Fabio (2021). Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma. JOURNAL OF HEPATOLOGY, vol. 74, pp. 1373-1385, ISSN:0168-8278 DOI

Taddei ML, Pietrovito L, Leo A, Chiarugi P (2020). Lactate in Sarcoma Microenvironment: Much More than just a Waste Product.. CELLS, vol. 9, pp. 510-532, ISSN:2073-4409 DOI Accesso ONLINE all'editore

Barisciano G, Colangelo T, Rosato V, Muccillo L, Taddei ML, Ippolito L, Chiarugi P, Galgani M, Bruzzaniti S, Matarese G, Fassan M, Agostini M, Bergamo F, Pucciarelli S, Carbone A, Mazzoccoli G, Colantuoni V, Bianchi F, Sabatino L (2020). miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer.. BRITISH JOURNAL OF CANCER, vol. 122, pp. 1354-1366, ISSN:0007-0920 DOI Accesso ONLINE all'editore

Calvani, Maura; Dabraio, Annalisa; Bruno, Gennaro; De Gregorio, Veronica; Coronnello, Marcella; Bogani, Costanza; Ciullini, Sara; Marca, Giancarlo la; Vignoli, Marina; Chiarugi, Paola; Nardi, Margherita; Vannucchi, Alessandro Maria; Filippi, Luca; Favre, Claudio (2020). β3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1-18, ISSN:1422-0067 DOI

Ippolito L.; Giannoni E.; Chiarugi P.; Parri M. (2020). Mitochondrial Redox Hubs as Promising Targets for Anticancer Therapy. FRONTIERS IN ONCOLOGY, vol. 10, pp. 256-268, ISSN:2234-943X DOI

Antonio Pezone, Maria Letizia Taddei, Alfonso Tramontano, Jacopo Dolcini, Francesca Ludovica Boffo, Mariarosaria De Rosa, Matteo Parri, Stefano Stinziani, Giuseppina Comito, Antonio Porcellini, Giovanni Raugei, Daniel Gackowski, Ewelina Zarakowska, Ryszard Olinski, Armando Gabrielli, Paola Chiarugi, Enrico Vittorio Avvedimento (2020). Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repression. NUCLEIC ACIDS RESEARCH, vol. 48, pp. 8943-8958, ISSN:0305-1048 DOI Accesso ONLINE all'editore

Pietrovito L.; Iozzo M.; Bacci M.; Giannoni E.; Chiarugi P. (2020). Treatment with Cannabinoids as a Promising Approach for Impairing Fibroblast Activation and Prostate Cancer Progression. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 787-803, ISSN:1422-0067 DOI

Comito G.; Ippolito L.; Chiarugi P.; Cirri P. (2020). Nutritional Exchanges Within Tumor Microenvironment: Impact for Cancer Aggressiveness. FRONTIERS IN ONCOLOGY, vol. 10, pp. 396-405, ISSN:2234-943X DOI

Parri M.; Ippolito L.; Cirri P.; Ramazzotti M.; Chiarugi P. (2020). Metabolic cell communication within tumour microenvironment: models, methods and perspectives. CURRENT OPINION IN BIOTECHNOLOGY, vol. 63, pp. 210-219, ISSN:0958-1669 DOI

Lorito, Nicla; Bacci, Marina; Smiriglia, Alfredo; Mannelli, Michele; Parri, Matteo; Comito, Giuseppina; Ippolito, Luigi; Giannoni, Elisa; Bonechi, Martina; Benelli, Matteo; Migliaccio, Ilenia; Malorni, Luca; Chiarugi, Paola; Morandi, Andrea (2020). Glucose Metabolic Reprogramming of ER Breast Cancer in Acquired Resistance to the CDK4/6 Inhibitor Palbociclib. CELLS, vol. 9, pp. 0-0, ISSN:2073-4409 DOI

BACCI M, IPPOLITO L, MAGNELLI L, GIANNONI E, CHIARUGI P (2019). Stromal-induced mitochondrial re-education: Impact on epithelial-to-mesenchymal transition and cancer aggressiveness.. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, vol. xx, pp. 0-0, ISSN:1084-9521 DOI Accesso ONLINE all'editore

Calvani, Maura; Bruno, Gennaro; Dal Monte, Massimo; Nassini, Romina; Fontani, Filippo; Casini, Arianna; Cavallini, Lorenzo; Becatti, Matteo; Bianchini, Francesca; De Logu, Francesco; Forni, Giulia; la Marca, Giancarlo; Calorini, Lido; Bagnoli, Paola; Chiarugi, Paola; Pupi, Alberto; Azzari, Chiara; Geppetti, Pierangelo; Favre, Claudio; Filippi, Luca (2019). β3-adrenoceptor as a potential immuno-suppressor agent in melanoma. BRITISH JOURNAL OF PHARMACOLOGY, vol. 176, pp. 2509-2524, ISSN:1476-5381 DOI

Comito, G.; Iscaro, A.; Bacci, M.; Morandi, A.; Ippolito, L.; Parri, M.; Montagnani, I.; Raspollini, M.R.; Serni, S.; Simeoni, L.; Giannoni, E.*; Chiarugi, P. (2019). Lactate modulates CD4 + T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis. ONCOGENE, vol. 38 (19), pp. 3681-3695, ISSN:0950-9232, Nature Publishing Group: DOI Accesso ONLINE all'editore

Bacci M.; Lorito N.; Ippolito L.; Ramazzotti M.; Luti S.; Romagnoli S.; Parri M.; Bianchini F.; Cappellesso F.; Virga F.; Gao Q.; Simoes B.M.; Marangoni E.; Martin L.-A.; Comito G.; Ferracin M.; Giannoni E.; Mazzone M.; Chiarugi P.; Morandi A. (2019). Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer. CELL REPORTS, vol. 28, pp. 104-118.e8, ISSN:2211-1247 DOI Accesso ONLINE all'editore

Pietrovito L, Comito G, Parri M, Giannoni E, Chiarugi P, Taddei ML. (2019). Zoledronic Acid Inhibits the RhoA-mediated Amoeboid Motility of Prostate Cancer Cells.. CURRENT CANCER DRUG TARGETS, vol. 19, pp. 807-816, ISSN:1873-5576 DOI

Ippolito, Luigi; Morandi, Andrea; Taddei, Maria Letizia; Parri, Matteo; Comito, Giuseppina; Iscaro, Alessandra; Raspollini, Maria Rosaria; Magherini, Francesca; Rapizzi, Elena; Masquelier, Julien; Muccioli, Giulio G; Sonveaux, Pierre; Chiarugi, Paola; Giannoni, Elisa (2019). Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer. ONCOGENE, vol. 38, pp. 5339-5355, ISSN:0950-9232 DOI Accesso ONLINE all'editore

Chen, Jingjing; Guccini, Ilaria; Mitri, Diletta Di; Brina, Daniela; Revandkar, Ajinkya; Sarti, Manuela; Pasquini, Emiliano; Alajati, Abdullah; Pinton, Sandra; Losa, Marco; Civenni, Gianluca; Catapano, Carlo V.; Sgrignani, Jacopo; Cavalli, Andrea; D'Antuono, Rocco; Asara, John M.; Morandi, Andrea; Chiarugi, Paola; Crotti, Sara; Agostini, Marco; Montopoli, Monica; Masgras, Ionica; Rasola, Andrea; Garcia-Escudero, Ramon; Delaleu, Nicolas; Rinaldi, Andrea; Bertoni, Francesco; Bono, Johann De; Carracedo, Arkaitz; Alimonti, Andrea (2018). Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer. NATURE GENETICS, vol. 50, pp. 219-228, ISSN:1061-4036 DOI Accesso ONLINE all'editore

Arosio, Paolo; Comito, Giuseppina; Orsini, Francesco; Lascialfari, Alessandro; Chiarugi, Paola; Ménard-Moyon, Cécilia*; Nativi, Cristina; Richichi, Barbara (2018). Conjugation of a GM3 lactone mimetic on carbon nanotubes enhances the related inhibition of melanoma-associated metastatic events. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 16, pp. 6086-6095, ISSN:1477-0520 DOI Accesso ONLINE all'editore

Apicella, Maria; Giannoni, Elisa; Fiore, Stephany; Ferrari, Karin Johanna; Fernández-Pérez, Daniel; Isella, Claudio; Granchi, Carlotta; Minutolo, Filippo; Sottile, Antonino; Comoglio, Paolo Maria; Medico, Enzo; Pietrantonio, Filippo; Volante, Marco; Pasini, Diego; Chiarugi, Paola; Giordano, Silvia; Corso, Simona (2018). Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies. CELL METABOLISM, vol. 28, pp. 848-865.e6-865.e6, ISSN:1550-4131 DOI

Pietrovito, Laura; Leo, Angela; Gori, Valentina; Lulli, Matteo; Parri, Matteo; Becherucci, Valentina; Piccini, Luisa; Bambi, Franco; Taddei, Maria Letizia; Chiarugi, Paola (2018). Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition. MOLECULAR ONCOLOGY, vol. 12, pp. 659-676, ISSN:1574-7891 DOI Accesso ONLINE all'editore

Taddei, Maria Letizia*; Cavallini, Lorenzo; Ramazzotti, Matteo; Comito, Giuseppina; Pietrovito, Laura; Morandi, Andrea; Giannoni, Elisa; Raugei, Giovanni; Chiarugi, Paola (2018). Stromal-induced downregulation of miR-1247 promotes prostate cancer malignancy. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 6, pp. 8274-8285, ISSN:0021-9541 DOI Accesso ONLINE all'editore

Maura Calvani , Lorenzo Cavallini, Annalisa Tondo , Valentina Spinelli , Luisa Ricci , Amada Pasha , Gennaro Bruno , Daniela Buonvicino , Elisabetta Bigagli , Marina Vignoli , Francesca Bianchini , Laura Sartiani , Maura Lodovici , Roberto Semeraro, Filippo Fontani , Francesco De Logu , Massimo Dal Monte , Paola Chiarugi, Claudio Favre , and Luca Filippi (2018). "β3-Adrenoreceptors Control Mitochondrial Dormancy in Melanoma and Embryonic Stem Cells,. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, pp. 1-10, ISSN:1942-0900

Ippolito, Luigi; Morandi, Andrea; Giannoni, Elisa; Chiarugi, Paola (2018). Lactate: A Metabolic Driver in the Tumour Landscape. TRENDS IN BIOCHEMICAL SCIENCES, pp. 153-166, ISSN:0968-0004 DOI

Sciortino, Niccolò; Fedeli, Stefano; Paoli, Paolo; Brandi, Alberto; Chiarugi, Paola; Severi, Mirko; Cicchi, Stefano (2017). Multiwalled carbon nanotubes for drug delivery: Efficiency related to length and incubation time. INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 521, pp. 69-72, ISSN:0378-5173 DOI Accesso ONLINE all'editore

Pistore C, Giannoni E, Colangelo T, Rizzo F, Magnani E, Muccillo L, Giurato G, Mancini M, Rizzo S, Riccardi M, Sahnane N, Del Vescovo V, Kishore K, Mandruzzato M, Macchi F, Pelizzola M, Denti MA, Furlan D, Weisz A, Colantuoni V, Chiarugi P, Bonapace IM (2017). DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.. ONCOGENE, vol. 36, pp. 5551-5566, ISSN:1476-5594 DOI Accesso ONLINE all'editore

Morandi, Andrea; Taddei, Maria Letizia; Chiarugi, Paola; Giannoni, Elisa (2017). Targeting the Metabolic Reprogramming That Controls Epithelial-to-Mesenchymal Transition in Aggressive Tumors. FRONTIERS IN ONCOLOGY, vol. 7:40, pp. 1-19, ISSN:2234-943X DOI Accesso ONLINE all'editore

Fragai, Marco; Comito, Giuseppina; Di Cesare Mannelli, Lorenzo; Gualdani, Roberta; Calderone, Vito; Louka, Alexandra; Richichi, Barbara; Francesconi, Oscar; Angeli, Andrea; Nocentini, Alessio; Gratteri, Paola; Chiarugi, Paola; Ghelardini, Carla; Tadini-Buoninsegni, Francesco; Supuran, Claudiu T; Nativi, Cristina (2017). Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX). JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 9003-9011, ISSN:1520-4804 DOI

Bacci, M; Giannoni, E; Fearns, A; Ribas, R; Gao, Q; Taddei, Ml; Pintus, G; Dowsett, M; Isacke, Cm; Martin, La; Chiarugi, P; Morandi, A (2016). miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors.. CANCER RESEARCH, vol. 76(6), pp. 1615-1626, ISSN:0008-5472 DOI Accesso ONLINE all'editore

Barcellos-de-Souza, P; Comito, G; Pons-Segura, C; Taddei, ML; Gori, V; Becherucci, V; Bambi, F; Margheri, F; Laurenzana, A; Del Rosso, M; Chiarugi, P; (2016). Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1. STEM CELLS, vol. 34, pp. 2536-2547, ISSN:1066-5099 DOI Accesso ONLINE all'editore

Comito, G; Segura, Cp; Taddei, Ml; Lanciotti, M; Serni, S; Morandi, A; Chiarugi, P; Giannoni, E (2016). Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts.. ONCOTARGET, vol. ..8, pp. 118-132, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Grandi, Alberto; Santi, Alice; Campagnoli, Susanna; Parri, Matteo; De Camilli, Elisa; Song, Chaojun; Jin, Boquan; Lacombe, Aurelien; Castori-Eppenberger, Serenella; Sarmientos, Paolo; Grandi, Guido; Viale, Giuseppe; Terracciano, Luigi; Chiarugi, Paola; Pileri, Piero; Grifantini, Renata (2016). ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer. ONCOTARGET, vol. 7, pp. 63596-63610, ISSN:1949-2553 DOI

Ippolito, Luigi; Marini, Alberto; Cavallini, Lorenzo; Morandi, Andrea; Pietrovito, Laura; Pintus, Gianfranco; Giannoni, Elisa; Schrader, Thomas; Puhr, Martin; Chiarugi, Paola; Taddei, Maria Letizia (2016). Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells.. ONCOTARGET, vol. 7, pp. 61890-61904, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Mattu, Sandra; Fornari, Francesca; Quagliata, Luca; Perra, Andrea; Angioni, Maria Maddalena; Petrelli, Annalisa; Menegon, Silvia; Morandi, Andrea; Chiarugi, Paola; Ledda-Columbano, Giovanna Maria; Gramantieri, Laura; Terracciano, Luigi; Giordano, Silvia; Columbano, Amedeo (2016). The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival. JOURNAL OF HEPATOLOGY, vol. 64, pp. 891-8-898, ISSN:0168-8278 DOI

Morandi, A; Giannoni, E.; Chiarugi, P (2016). Nutrient Exploitation within the Tumor–Stroma Metabolic Crosstalk. TRENDS IN CANCER, vol. 2, pp. 736-746, ISSN:2405-8033 DOI Accesso ONLINE all'editore

Kowalik, Marta Anna; Guzzo, Giulia; Morandi, Andrea; Perra, Andrea; Menegon, Silvia; Masgras, Ionica; Trevisan, Elena; Angioni, Maria Maddalena; Fornari, Francesca; Quagliata, Luca; Ledda-Columbano, Giovanna Maria; Gramantieri, Laura; Terracciano, Luigi; Giordano, Silvia; Chiarugi, Paola; Rasola, Andrea; Columbano, Amedeo (2016). Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis. ONCOTARGET, vol. 7, pp. 32375-32393, ISSN:1949-2553 DOI

Andreucci, Elena; Francica, Paola; Fearns, Antony; Martin, Lesley-Ann; Chiarugi, Paola; Isacke, Clare M; Morandi, Andrea (2016). Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts. ONCOTARGET, vol. 7, pp. 80543--80553, ISSN:1949-2553 DOI

Fedeli, S.; Brandi, A.; Venturini, L.; Chiarugi, P.; Giannoni, E.; Paoli, P.; Corti, D.; Giambastiani, G.; Tuci, G.; Cicchi, S. (2016). The ”click-on-tube” approach for the production of efficient drug carriers based on oxidize multiwalled carbon nanotubes. JOURNAL OF MATERIALS CHEMISTRY. B, vol. 4, pp. 3823-3831, ISSN:2050-7518 DOI Accesso ONLINE all'editore

Richichi, Barbara; Comito, Giuseppina; Renaudet, Olivier; Fiore, Michele; Marra, A.; Stecca, B.; Pasquato, L.; Chiarugi, P.; Nativi, C. (2016). Role of a Preorganized Scaffold Presenting Four Residues of a GM‑3 Lactone Mimetic on Melanoma Progression. ACS MEDICINAL CHEMISTRY LETTERS, vol. 7, pp. 28-33, ISSN:1948-5875 DOI Accesso ONLINE all'editore

Calvani, M; Bianchini, F; Taddei, Ml; Becatti, M; Giannoni, E; Chiarugi, P; Calorini, L1. (2016). Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits. ONCOTARGET, vol. 7(33), pp. 51138-51149, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Pietrobono, Silvia; Morandi, Andrea; Gagliardi, Sinforosa; Gerlini, Gianni; Borgognoni, Lorenzo; Chiarugi, Paola; Arbiser, Jack L; Stecca, Barbara (2016). Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival. JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 136, pp. 2059-2069-2069, ISSN:0022-202X DOI

Denise, Corti; Paolo, Paoli; Maura, Calvani; Maria Letizia, Taddei; Elisa, Giannoni; Scott, Kopetz; Syed Mohammad Ali, Kazmi; Maria Pia, Morelli; Piergiorgio, Pettazzoni; Elena, Sacco; Anna, Caselli; Marco, Vanoni; Matteo, Landriscina; Paolo, Cirri; Paola, Chiarugi. (2015). 5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like trait. ONCOTARGET, vol. 6, pp. 41706-41721, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Chiarugi, P; Filippi, L (2015). β3-adrenoreceptor and tumor microenvironment: a new hub. ONCOIMMUNOLOGY, vol. 4(11), pp. 0-0, ISSN:2162-4011

Giannoni, E; Taddei, Ml; Morandi, A; Comito, G; Calvani, M; Bianchini, F; Richichi, B; Raugei, G; Wong, N; Tang, D; Chiarugi, P. (2015). Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread. ONCOTARGET, vol. 6(27), pp. 24061-24074, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Calvani M, Pelon F, Comito G, Taddei ML, Moretti S, Innocenti S, Nassini R, Gerlini S, Borgognoni, Bambi F, Giannoni E, Filippi L, Chiarugi P. (2015). Norepinephrine promotes tumor microenvironment reactivity through β3-adrenoreceptors during melanoma progression.. ONCOTARGET, vol. 6, pp. 4615-4632, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Chiarugi, Paola; Dello Sbarba, Persio (2015). Cancer stemness and progression: Mitochondria on the stage. ONCOTARGET, vol. 6, pp. 36924-36925, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Doldi, V; Callari, M; Giannoni, E; D'Aiuto, F; Maffezzini, M; Valdagni, R; Chiarugi, P; Gandellini, P; Zaffaroni, N. (2015). Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation.. ONCOTARGET, vol. 6(31), pp. 31441-31460, ISSN:1949-2553 DOI

Chiarugi Paola; Cirri Paolo (2015). Metabolic exchanges within tumor microenvironment.. CANCER LETTERS, vol. 380, pp. 272-280, ISSN:0304-3835

Morandi A; Chiarugi P (2014). Metabolic implication of tumor:stroma crosstalk in breast cancer.. JOURNAL OF MOLECULAR MEDICINE, vol. 92, pp. 117-126, ISSN:0946-2716 DOI

Matteo Parri; Laura Pietrovito; Alberto Grandi; Susanna Campagnoli; Elisa De Camilli; Francesca Bianchini; Serena Marchiò; Federico Bussolino ; Boquan Jin; Paolo Sarmientos; Guido Grandi; Giuseppe Viale; Piero Pileri; Paola Chiarugi; Renata Grifantini. (2014). Angiopoietin like 7, a novel pro-angiogenetic factor over-expressed in cancer. ANGIOGENESIS, pp. 0-0, ISSN:0969-6970 DOI

Lanciotti M; Masieri L; Raspollini MR; Minervini A; Mari A; Comito G; Giannoni E; Carini M; Chiarugi P; Serni S (2014). The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy. BIOMED RESEARCH INTERNATIONAL, vol. 3, pp. 20-31, ISSN:2314-6133 DOI

Taddei ML; Cavallini L; Comito G; Giannoni E; Folini M; Marini A; Gandellini P; Morandi A; Pintus G; Raspollini MR; Zaffaroni N; Chiarugi P. (2014). Senescent stroma promotes prostate cancer progression: The role of miR-210. MOLECULAR ONCOLOGY, pp. 1729-1746, ISSN:1574-7891 DOI

Taddei ML; Giannoni E; Morandi A; Ippolito L; Ramazzotti M; Callari M; Gandellini P; Chiarugi P (2014). Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells. CELL COMMUNICATION AND SIGNALING, vol. 24, pp. 1-12, ISSN:1478-811X DOI

Chiarugi P; Paoli P; Cirri P. (2014). Tumor microenvironment and metabolism in prostate cancer.. SEMINARS IN ONCOLOGY, vol. 41, pp. 267-280, ISSN:0093-7754 DOI Accesso ONLINE all'editore

Gandellini P; Giannoni E; Casamichele A; Taddei ML; Callari M; Piovan C; Valdagni R; Pierotti MA; Zaffaroni N; Chiarugi P. (2014). miR-205 Hinders the Malignant Interplay Between Prostate Cancer Cells and Associated Fibroblasts. ANTIOXIDANTS & REDOX SIGNALING, vol. 20(7), pp. 1045-1059, ISSN:1523-0864

Giannoni E; Chiarugi P. (2014). Redox Circuitries Driving Src Regulation.. ANTIOXIDANTS & REDOX SIGNALING, vol. 20(13), pp. 2011-2025, ISSN:1523-0864

Comito G; Giannoni E; Segura CP; Barcellos-de-Souza P; Raspollini MR; Baroni G; Lanciotti M; Serni S; Chiarugi P. (2014). Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression.. ONCOGENE, vol. 33(19), pp. 2423-2431, ISSN:0950-9232 DOI

Margheri F; Luciani C; Taddei ML; Giannoni E; Laurenzana A; Biagioni A; Chillà A; Chiarugi P; Fibbi G; Del Rosso M (2014). The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style.. ONCOTARGET, vol. 5(6), pp. 1538-1553, ISSN:1949-2553

S. Moretti; D. Massi; V. Farini; G. Baroni; M. Parri; S. Innocenti; R. Cecchi; P. Chiarugi (2013). β-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines.. LABORATORY INVESTIGATION, vol. 93, pp. 279-290, ISSN:1530-0307

Giannoni E; Taddei ML; Parri M; Bianchini F; Santosuosso M; Grifantini R; Fibbi G; Mazzanti B; Calorini L; Chiarugi P. (2013). EphA2-mediated mesenchymal-amoeboid transition induced by endothelial progenitor cells enhances metastatic spread due to cancer-associated fibroblasts.. JOURNAL OF MOLECULAR MEDICINE, vol. 91(1), pp. 103-115, ISSN:0946-2716

S. Serratì; A. Chillà; A. Laurenzana; F. Margheri; E. Giannoni; L. Magnelli; P. Chiarugi ; J. Dotor; E. Feijoo; L. Bazzichi; S. Bombardieri; B. Kahaleh; G. Fibbi; M. Del Rosso (2013). Systemic sclerosis endothelial cells recruit and activate dermal fibroblasts by induction of a CTGF(CCN2)/TGF-beta-dependent mesechymal-to mesenchymal transition. ARTHRITIS AND RHEUMATISM, vol. 65(1), pp. 258-269, ISSN:1529-0131 DOI

Tania Fiaschi;Elisa Giannoni;Maria Letizia Taddei;Paolo Cirri;Alberto Marini;Gianfranco Pintus;Cristina Nativi;Barbara Richichi;Andrea Scozzafava;Fabrizio Carta;Eugenio Torre;Claudiu T. Supuran;Paola Chiarugi (2013). Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells. CELL CYCLE, vol. 12, pp. 1791-1801, ISSN:1538-4101 DOI

Alice Santi; Anna Caselli; Paolo Paoli; Denise Corti; Guido Camici; Giuseppe Pieraccini; Maria L Taddei; Sergio Serni; Paola Chiarugi; Paolo Cirri (2013). The effects of CA IX catalysis products within tumor microenvironment. CELL COMMUNICATION AND SIGNALING, vol. 11, pp. 0-0, ISSN:1478-811X DOI Accesso ONLINE all'editore

Pitozzi, Vanessa; Mocali, Alessandra; Laurenzana, Anna; Giannoni, Elisa; Cifola, I.; Battaglia, C.; Chiarugi, Paola; Dolara, Piero; Giovannelli, Lisa (2013). Chronic Resveratrol Treatment Ameliorates Cell Adhesion and Mitigates the Inflammatory Phenotype in Senescent Human Fibroblasts. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, vol. 68, pp. 371-381, ISSN:1079-5006 DOI

Cirri P; Chiarugi P (2013). Tumors and their stroma: mitochondria at the crossroad.. CELL CYCLE, vol. 12, pp. 204-205, ISSN:1538-4101

Parri M; Chiarugi P. (2013). Redox molecular machines involved in tumor progression.. ANTIOXIDANTS & REDOX SIGNALING, vol. 20, pp. 1828-1845, ISSN:1523-0864

Barbara Richichi;Giuseppina Comito;Linda Cerofolini;Gabriele Gabrielli;Alberto Marra;Lisa Moni;Alice Pace;Lucia Pasquato;Paola Chiarugi;Alessandro Dondoni;Lucio Toma;Cristina Nativi (2013). Multivalent presentation of ahydrolytically stable GM 3 lactone mimetic as modulator of melanoma cells motility and adhesion. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 2756-2763, ISSN:0968-0896 DOI

Paoli P; Giannoni E; Chiarugi P. (2013). Anoikis molecular pathways and its role in cancer progression.. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, vol. 1833, pp. 3481-3498, ISSN:0167-4889 DOI Accesso ONLINE all'editore

Taddei ML; Giannoni E; Comito G; Chiarugi P. (2013). Microenvironment and tumor cell plasticity: An easy way out.. CANCER LETTERS, pp. ?-?, ISSN:0304-3835

chiarugi p (2013). Cancer associated fibroblasts and macrophages: friendly conspirators for tumor malignancy. ONCOIMMUNOLOGY, pp. 25563-25565, ISSN:2162-4011

Fiaschi T; Chiarugi P. (2012). Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison.. INTERNATIONAL JOURNAL OF CELL BIOLOGY, pp. 762-769, ISSN:1687-8876 DOI

Maria Letizia Taddei, Elisa Giannoni, Giovanni Raugei, Salvatore Scacco, AnnaMaria Sardanelli, Sergio Papa, Paola Chiarugi (2012). Mitochondrial oxidative stress due to complex I dysfunction promotes fibroblast activation and melanoma cell invasiveness. JOURNAL OF SIGNAL TRANSDUCTION (ONLINE), pp. 0-0, ISSN:2090-1747 DOI

Matteo Parri; Paola Chiarugi (2012). REDOX MOLECULAR MACHINES INVOLVED IN TUMOR PROGRESSION. ANTIOXIDANTS & REDOX SIGNALING, vol. 18, pp. 0-0, ISSN:1523-0864

Fiaschi T; Marini A; Giannoni E; Taddei ML; Gandellini P; De Donatis A; Lanciotti M; Serni S; Cirri P; Chiarugi P. (2012). RECIPROCAL METABOLIC REPROGRAMMING THROUGH LACTATE SHUTTLE COORDINATELY INFLUENCES TUMOR-STROMA INTERPLAY.. CANCER RESEARCH, vol. 72, pp. 5130-5140, ISSN:0008-5472

Crescioli C; Sottili M; Bonini P; Cosmi L; Chiarugi P; Romagnani P; Vannelli GB; Colletti M; Isidori AM; Serio M; Lenzi A; Di Luigi L. (2012). Inflammatory response in human skeletal muscle cells: CXCL10 as a potential therapeutic target.. EUROPEAN JOURNAL OF CELL BIOLOGY, vol. 91, pp. 139-149, ISSN:0171-9335 DOI

Fiaschi T; Cozzi G; Chiarugi P. (2012). Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement.. JOURNAL OF SIGNAL TRANSDUCTION, pp. 762-769, ISSN:2090-1739

Giannoni E; Parri M; Chiarugi P (2012). EMT and Oxidative Stress: A Bidirectional Interplay Affecting Tumor Malignancy. ANTIOXIDANTS & REDOX SIGNALING, vol. ---, pp. ---, ISSN:1523-0864

P. Cirri ; P. Chiarugi (2012). Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression. CANCER METASTASIS REVIEWS, vol. 31, pp. 195-208, ISSN:0167-7659

Fiaschi T; Giannoni E; Taddei ML; Chiarugi P (2012). Globular adiponectin activates motility and regenerative traits of muscle satellite cells.. PLOS ONE, vol. 7, pp. -----, ISSN:1932-6203

Bianchini F; Giannoni E; Serni S; Chiarugi P; Calorini L. (2012). 22 : 6n-3 DHA inhibits differentiation of prostate fibroblasts into myofibroblasts and tumorigenesis.. BRITISH JOURNAL OF NUTRITION, vol. 108, pp. 2129-2137, ISSN:1475-2662 DOI

Retta SF; Chiarugi P; Trabalzini L; Pinton P; Belkin AM. (2012). Reactive oxygen species: friends and foes of signal transduction.. JOURNAL OF SIGNAL TRANSDUCTION, pp. 534-540, ISSN:2090-1739

Comito G; Giannoni E; Gennaro PD; Segura CP; Gerlini G; Chiarugi P. (2012). Stromal fibroblasts synergize with hypoxic oxidative stress to enhance melanoma aggressiveness.. CANCER LETTERS, vol. ----, pp. ----------, ISSN:0304-3835

Calvani M; Comito G; Giannoni E; Chiarugi P. (2012). Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species.. PLOS ONE, vol. 7(10), pp. 1-11, ISSN:1932-6203

Maria Letizia Taddei; Elisa Giannoni; Giovanni Raugei; Salvatore Scacco; Anna Maria Sardanelli; Sergio Papa; Paola Chiarugi (2012). Mitochondrial Oxidative Stress due to Complex I Dysfunction Promotes Fibroblast Activation and Melanoma Cell Invasiveness. JOURNAL OF SIGNAL TRANSDUCTION (ONLINE), vol. 2012, pp. 1-10, ISSN:2090-1747 DOI

ML.Taddei; E.Giannoni; T. Fiaschi; P.Chiarugi (2012). Anoikis: an emerging hallmark in health and diseases.. JOURNAL OF PATHOLOGY, vol. 226, pp. 380-393, ISSN:0022-3417 DOI

Taddei ML; Parri M; Angelucci A; Bianchini F; Marconi C; Giannoni E; Raugei G; Bologna M; Calorini L; Chiarugi P (2011). EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells. MOLECULAR CANCER RESEARCH, vol. 9(2), pp. 149-160, ISSN:1541-7786

G. Comito; M. Calvani; E. Giannoni; F. Bianchini; L. Calorini; E. Torre; C. Migliore; S. Giordano; P. Chiarugi (2011). HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells.. FREE RADICAL BIOLOGY & MEDICINE, vol. 51(4), pp. 893-904, ISSN:0891-5849 DOI

P. Cirri ; P. Chiarugi (2011). Cancer associated fibroblasts: the dark side of the coin. AMERICAN JOURNAL OF CANCER RESEARCH, vol. 1, pp. 482-497, ISSN:2156-6976

E. Giannoni; F. Bianchini; L. Calorini; P. Chiarugi (2011). Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness.. ANTIOXIDANTS & REDOX SIGNALING, vol. 14(12), pp. 2361-2371, ISSN:1523-0864

Chiarugi P; Fiaschi T.Chiarugi P; Fiaschi T. (2010). Adiponectin in health and diseases: from metabolic syndrome to tissue regeneration.. EXPERT OPINION ON THERAPEUTIC TARGETS, vol. 14, pp. 193-201, ISSN:1472-8222

Pani G; Galeotti T; Chiarugi P. (2010). Metastasis: cancer cell's escape from oxidative stress.. CANCER METASTASIS REVIEWS, vol. 2, pp. 351-378, ISSN:0167-7659

Serni S.; Giannoni E.; Masieri L.; Calorini L.; Lanciotti M.; lerardi A.; Minervini A.; Lapini A.; Carini M.; Chiarugi P. (2010). ROLE OF STROMAL FIBROBLASTS INTERACTION WITH PROSTATIC CANCER CELLS IN ACHIEVEMENT OF METASTATIC PHENOTYPE.. In: 25th EAU Congress, Barcellona, 16-20 aprile, Elsevier Italia, vol. 9, pp. 114-115.

S. Serni; E. Giannoni; L. Masieri; L. Calorini; M. Lanciotti; A. Lerardi; A. Minervini; A. Lapini; M. Carini; P. Chiarugi. (2010). Role of stromal fibroblasts interaction with prostatic cancer cells in achievement of metastatic phenotype.. EUROPEAN UROLOGY. SUPPLEMENTS, vol. 9, pp. 114-115, ISSN:1569-9056

E. Giannoni; F. Bianchini; L. Masieri;S. Serni; E. Torre; L. Calorini; P. Chiarugi (2010). Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness.. CANCER RESEARCH, vol. 70(17), pp. 6945-6956, ISSN:0008-5472 DOI

Parri M; Chiarugi P. (2010). Rac and Rho GTPases in cancer cell motility control.. CELL COMMUNICATION AND SIGNALING, vol. 8, pp. 15-23, ISSN:1478-811X

Giannoni E; Taddei ML; Chiarugi P. (2010). SRC redox regulation: Again in the frontline.. FREE RADICAL BIOLOGY & MEDICINE, vol. 49, pp. 516-527, ISSN:0891-5849

Fiaschi T; Tedesco FS; Giannoni E; Diaz-Manera J; Parri M; Cossu G; Chiarugi P. (2010). Globular adiponectin as a complete mesoangioblast regulator: role in proliferation, survival, motility, and skeletal muscle differentiation.. MOLECULAR BIOLOGY OF THE CELL, vol. 21, pp. 848-859, ISSN:1059-1524

Chiarugi P (2010). Escaping from, moving towards, following a path, squeezing through: lots of opportunities for moving cells.. CELL COMMUNICATION AND SIGNALING, vol. 8, pp. 25-30, ISSN:1478-811X

T Fiaschi; D Cirelli; G Comito; S Gelmini; G Ramponi; M Serio; P Chiarugi (2009). Globular adiponectin induces differentiation and fusion of skeletal muscle cells. CELL RESEARCH, vol. 19(5), pp. 584-597, ISSN:1001-0602

M.Parri; ML.Taddei; F.Bianchini; L.Calorini; P.Chiarugi (2009). EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style. CANCER RESEARCH, vol. 69, pp. 2072-2081, ISSN:0008-5472

S. Serni; E. Giannoni; L. Calorini; L. Masieri; M. Lanciotti; A. Minervini; A. Lapini; M. Carini; P. Chiarugi (2009). RUOLO DELL’INTERAZIONE TRA FIBROBLASTI STROMALI E CELLULE DI CARCINOMA PROSTATICO NELL’ACQUISIZIONE DI UN FENOTIPO METASTATICO.. In: 82à Congresso SIU, Rimini, 4-7 ottobre, Società Italiana di Urologia, vol. Atti 82° Congresso SIU, pp. 171-171.

Chirasani SR; Markovic DS; Synowitz M; Eichler SA; Wisniewski P; Kaminska B; Otto A; Wanker E; Schäfer M; Chiarugi P; Meier JC; Kettenmann H; Glass R. (2009). Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells.. JOURNAL OF MOLECULAR MEDICINE, vol. 87, pp. 163-187, ISSN:0946-2716

E.Rapizzi; M.L.Taddei; T.Fiaschi; C.Donati; P. Bruni; P. Chiarugi (2009). Sphingosine 1-phosphate increases glucose uptake through trans-activation of insulin receptor.. CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 66, pp. 3207-3218, ISSN:1420-682X Accesso ONLINE all'editore

Pani G.; Giannoni E.; Galeotti T.; Chiarugi P. (2009). Redox-based escape mechanism from death: the cancer lesson.. ANTIOXIDANTS & REDOX SIGNALING, vol. 11, pp. 2791-2806, ISSN:1523-0864

ML.Taddei; M.Parri; A.Angelucci; B.Onnis; F.Bianchini; E.Giannoni; G.Raugei; L.Calorini; N.Rucci; A.Teti; M.Bologna; P.Chiarugi. (2009). Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis. THE AMERICAN JOURNAL OF PATHOLOGY, vol. 174, pp. 1492-1503, ISSN:0002-9440

Giannoni E.; Fiaschi T.; Ramponi G.; Chiarugi P. (2009). Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals.. ONCOGENE, vol. 28, pp. 2074-2086, ISSN:0950-9232

Chiarugi P (2009). Survival or death: the redox paradox.. ANTIOXIDANTS & REDOX SIGNALING, vol. 11, pp. 2651-2660, ISSN:1523-0864

P. CHIARUGI (2008). From anchorage dependent proliferation to survival: lessons from redox signalling.. IUBMB LIFE, vol. 60, pp. 301-307, ISSN:1521-6543 DOI

E. Giannoni; F. Buricchi; G. Grimaldi; M. Parri; F. Cialdai; L. Taddei; G. Raugei; G. Ramponi; P. Chiarugi (2008). Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival.. CELL DEATH AND DIFFERENTIATION, vol. 15(5), pp. 867-878, ISSN:1350-9047

P. Chiarugi; E. Giannoni (2008). Anoikis: A necessary death program for anchorage-dependent cells.. BIOCHEMICAL PHARMACOLOGY, vol. 76(11), pp. 1352-1364, ISSN:0006-2952

P. CHIARUGI (2008). Src redox regulation: there is more than meets the eye.. MOLECULES AND CELLS, vol. 26, pp. 329-337, ISSN:1016-8478

T. FIASCHI; F. BURICCHI; G. COZZI; S. MATTHIAS; M. PARRI; G. RAUGEI; G. RAMPONI; P. CHIARUGI (2007). Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin. HEPATOLOGY, vol. 46, pp. 130-139, ISSN:0270-9139, Falk Foundation EV:PO Box 6529, D-79041 Freiburg Germany:011 49 761 130340, Fax: 011 49 761 1303421: DOI Accesso ONLINE all'editore

P. CHIARUGI; T. FIASCHI (2007). Redox signalling in anchorage-dependent cell growth. CELLULAR SIGNALLING, vol. 19, pp. 672-682, ISSN:0898-6568

M. Taddei ; M. Parri; T. Mello; A. Catalano; A. Levine; G. Raugei; G. Ramponi; P. Chiarugi (2007). Integrin-mediated cell adhesion and spreading engage different sources of reactive oxygen species.. ANTIOXIDANTS & REDOX SIGNALING, vol. 9, pp. 469-481, ISSN:1523-0864 DOI Accesso ONLINE all'editore

P. CHIARUGI; F. BURICCHI (2007). Protein tyrosine phosphorylation and reversible oxidation: two cross-talking posttranslation modifications. ANTIOXIDANTS & REDOX SIGNALING, vol. 9, pp. 1-24, ISSN:1523-0864

M. PARRI; F. BURICCHI; E. GIANNONI; G. GRIMALDI; T. MELLO; G. RAUGEI; G. RAMPONI; P. CHIARUGI (2007). EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 282(27), pp. 19619-19628, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824:

F. Buricchi; E. Giannoni; G. Grimaldi; M. Parri; G. Raugei; G. Ramponi; P. Chiarugi (2007). Redox regulation of ephrin/integrin cross-talk. CELL ADHESION & MIGRATION, vol. 1, pp. 33-42, ISSN:1933-6918

j. LLUIS; F. BURICCHI ; P. CHIARUGI; A. MORALES; J. FERNANDEZ-CHECA (2007). Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death. CANCER RESEARCH, vol. 67(15), pp. 7368-7377, ISSN:0008-5472, American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228:

T. FIASCHI; G. COZZI; G. RAUGEI; L. FORMIGLI; G. RAMPONI; P. CHIARUGI (2006). Redox regulation of beta-actin during integrin-mediated cell adhesion. J Biol Chem. 2006 Aug 11;281(32):22983-91. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281, pp. 22983-22991, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824: Accesso ONLINE all'editore

E. GIANNONI; G. RAUGEI; P. CHIARUGI; G. RAMPONI (2006). A novel redox-based switch: LMW-PTP oxidation enhances Grb2 binding and leads to ERK activation.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 348(2), pp. 367-373, ISSN:0006-291X

M. TADDEI; P. CHIARUGI; C. CUEVAS; G. RAMPONI; G. RAUGEI (2006). Oxidation and inactivation of low molecular weight protein tyrosine phosphatase by the anticancer drug Aplidin. INTERNATIONAL JOURNAL OF CANCER, vol. 118, pp. 2082-2088, ISSN:0020-7136 DOI

Fiaschi T.; Cozzi G.; Raugei G.; Formigli L.; Ramponi G.; Chiarugi P. (2006). Redox regulation of β-actin during integrin-mediated cell adhesion. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281, pp. 22983-22991, ISSN:0021-9258 DOI

M. PARRI; F. BURICCHI; L. TADDEI; E. GIANNONI; G. RAUGEI; G. RAMPONI; P. CHIARUGI (2005). EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280(40), pp. 34008-34018, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824:

P.Chiarugi; ML.Taddei; G.Ramponi (2005). Oxidation and tyrosine phosphorylation: synergistic or antagonistic cues in protein tyrosine phosphatase.. CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 62, pp. 931-936, ISSN:1420-9071

P. CIRRI; M. TADDEI; P. CHIARUGI; F. BURICCHI; A. CASELLI; P. PAOLI; E. GIANNONI; G. CAMICI; G. MANAO; G. RAUGEI; G. RAMPONI (2005). INSULIN INHIBITS PLATELET-DERIVED GROWTH FACTOR-INDUCED CELL PROLIFERATION. MOLECULAR BIOLOGY OF THE CELL, vol. 16, pp. 73-83, ISSN:1059-1524 DOI

P. CHIARUGI (2005). PTPs versus PTKs: the redox side of the coin. FREE RADICAL RESEARCH, vol. 39, pp. 353-364, ISSN:1071-5762

P. Chiarugi; E. Giannoni (2005). Anchorage-dependent cell growth: tyrosine kinases and phosphatases meet redox regulation.. ANTIOXIDANTS & REDOX SIGNALING, vol. 7(5-6), pp. 578-592, ISSN:1523-0864

F. BURICCHI; P. CHIARUGI; T. FIASCHI; E. GIANNONI; L. MAGNELLI; E. FANTI; G. RAUGEI; G. RAMPONI (2005). DURING MUSCLE AGEING THE ACTIVATION OF THE MITOGENIC SIGNALLING IS NOT SUFFICIENT TO GUARANTEE CELLULAR DUPLICATION.. ITALIAN JOURNAL OF BIOCHEMISTRY, vol. 54, pp. 458-467, ISSN:0021-2938

E. GIANNONI; F. BURICCHI; G. RAUGEI; G. RAMPONI; P. CHIARUGI (2005). Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth.. MOLECULAR AND CELLULAR BIOLOGY, vol. 25(15), pp. 6391-6403, ISSN:0270-7306, American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342:

P. CHIARUGI; ML. TADDEI; N. SCHIAVONE; L. PAPUCCI; E. GIANNONI; T FIASCHI; S. CAPACCIOLI; G. RAUGEI; G. RAMPONI (2004). LMW-PTP is a positive regulator of tumor onset and growth. ONCOGENE, vol. 23, pp. 3905-3914, ISSN:0950-9232 DOI Accesso ONLINE all'editore

Cirri P.; Taddei M.L.; Chiarugi P.; Buricchi F.; Caselli A.; Paoli P.; Giannoni E.; Camici G.; Manao G.; Raugei G.; Ramponi G. (2003). Insulin inhibits platelet-derived growth factor-induced cell proliferation. In: SIB 2003, vol. 52, pp. 40-40.

Cirri P.; Taddei M.L.; Chiarugi P.; Caselli A.; Paoli P.; Giannoni E.; Camici G.; Manao G.; Raugei G.; Ramponi G. (2003). Insulin strongly inhibits PDGF-induced cell proliferation. In: Protein sciences 2003, vol. 12 (1), pp. 123-123.

P. CHIARUGI; G. PANI; E. GIANNONI; L. TADDEI; R. COLAVITTI; G. RAUGEI; M. SYMONS; S. BORRELLO; T. GALEOTTI; G. RAMPONI (2003). Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.. THE JOURNAL OF CELL BIOLOGY, vol. 161(5), pp. 933-944, ISSN:0021-9525

P. CHIARUGI ; P. CIRRI; (2003). Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction.. TRENDS IN BIOCHEMICAL SCIENCES, vol. 28, pp. 509-514, ISSN:0968-0004, Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010: Accesso ONLINE all'editore

T. FIASCHI; P. CHIARUGI; F. BURICCHI; E. GIANNONI; L. TADDEI; L. MAGNELLI; G. COZZI; G. RAUGEI; G. RAMPONI (2003). Down-regulation of platelet-derived growth factor receptor signaling during myogenesis.. CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 60(12), pp. 2721-2735, ISSN:1420-682X DOI Accesso ONLINE all'editore

P. CHIARUGI (2003). Reactive oxygen species as mediators of cell adhesion. ITALIAN JOURNAL OF BIOCHEMISTRY, vol. 52, pp. 28-32, ISSN:0021-2938

E. GIANNONI; P. CHIARUGI; G. COZZI; L. MAGNELLI; L. TADDEI; T. FIASCHI; F. BURICCHI; G. RAUGEI; G. RAMPONI (2003). Lymphocyte function-associated antigen-1-mediated T cell adhesion is impaired by low molecular weight phosphotyrosine phosphatase-dependent inhibition of FAK activity. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278(38), pp. 36763-36776, ISSN:0021-9258 DOI Accesso ONLINE all'editore

P. CHIARUGI (2002). The redox regulation of LMW-PTP during cell proliferation or growth inhibition. ITALIAN JOURNAL OF BIOCHEMISTRY, vol. 52, pp. 55-59, ISSN:0021-2938

P. Chiarugi; P. Cirri; ML. Taddei.; E. Giannoni; T. Fiaschi; F. Buricchi; G. Camici; G. Raugei; G. Ramponi (2002). Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, pp. 37331-37338, ISSN:0021-9258 DOI Accesso ONLINE all'editore

RAUGEI G; G. RAMPONI; CHIARUGI P (2002). Low molecular weight protein tyrosine phosphatases:small, but smart. CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 59, pp. 941-949, ISSN:1420-682X

ML. TADDEI ; P. CHIARUGI ; P. CIRRI; F. BURICCHI ; T. FIASCHI ; E. GIANNONI ; D. TALINI ; G. COZZI ; L. FORMIGLI ; G. RAUGEI ; G. RAMPONI (2002). Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.. CANCER RESEARCH, vol. 62, pp. 6489-6499, ISSN:0008-5472

P. CHIARUGI; P. CIRRI; M. TADDEI; D. TALINI; F. BURICCHI; E. GIANNONI; G. CAMICI; G. RAUGEI; G. RAMPONI; L. DORIA; T. FIASCHI (2002). New perspectives in PDGF receptor downregulation: the main role of phosphotyrosine phosphatases. JOURNAL OF CELL SCIENCE, vol. 115, pp. 2219-2232, ISSN:0021-9533 Accesso ONLINE all'editore

P. CHIARUGI; T. FIASCHI; L. TADDEI; D. TALINI; E. GIANNONI; G. RAUGEI; G. RAMPONI (2001). Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276(36), pp. 33478-33487, ISSN:0021-9258

T. FIASCHI; P. CHIARUGI; F. BURICCHI; E. GIANNONI; L. TADDEI; D. TALINI; G. COZZI; S. ZECCHI; G. RAUGEI; G. RAMPONI (2001). Low molecular weight protein-tyrosine phosphatase is involved in growth inhibition during cell differentiation.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276(52), pp. 49156-49163, ISSN:0021-9258

Taddei M.L; Chiarugi P; Cirri P; Talini D; Camici G; Manao G; Raugei G; Ramponi G. (2000). LMW-PTP exerts a differential regulation on PDGF- and insulin-mediated signaling.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 270, pp. 564-569, ISSN:0006-291X DOI Accesso ONLINE all'editore

P. CHIARUGI; P. CIRRI; M. TADDEI; E. GIANNONI; G. CAMICI; G. MANAO; G. RAUGEI; G. RAMPONI (2000). The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, pp. 4640-4646, ISSN:0021-9258 Accesso ONLINE all'editore

T. Fiaschi; P. Chiarugi; D. Veggi; G. Raugei; G. Ramponi (2000). The inhibitory effect of the 5' untranslated region of muscle acylphosphatase mRNA on protein expression is relieved during cell differentiation.. FEBS LETTERS, vol. 473, pp. 42-46, ISSN:0014-5793 Accesso ONLINE all'editore

Chiarugi P.; Taddei M.L.; Cirri P.; Talini D.; Buricchi F.; Camici G.; G. Manao; Raugei G.; Ramponi G. (2000). Low molecular weight protein-tyrosine phosphatase controls the rate and the strength of NIH-3T3 cells adhesion through its phosphorylation on tyrosine 131 or 132. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, pp. 37619-37627, ISSN:0021-9258 DOI Accesso ONLINE all'editore

ML. TADDEI ; P. CHIARUGI ; L. BROGELLI ; P. CIRRI; L. MAGNELLI ; G. RAUGEI ; M. ZICHE ; HJ.GRANGER ; V. CHIARUGI ; G. RAMPONI (1999). Inhibitory effect of full-length human endostatin on in vitro angiogenesis.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 263, pp. 340-345, ISSN:0006-291X DOI Accesso ONLINE all'editore

L. CIRRI; S. DONNINI; L. MORBIDELLI; P. CHIARUGI; M. ZICHE; F. LEDDA (1999). Endostatin: a promising drug for antiangiogenic therapy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, vol. 14, pp. 263-267, ISSN:0141-8130

RAUGEI G; DEGL'INNOCENTI D; CHIARUGI P; SOLITO E; A. MODESTI; RAMPONI G (1999). Preferential accumulation of muscle type acylphosphatase in the nucleus during differentiation. BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, vol. 47(1), pp. 127-136, ISSN:1039-9712, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445:

M. Bucciantini; P.Chiarugi; P.Cirri; L.Taddei; M.Stefani; G.Raugei; P. Nordlund; G.Ramponi (1999). The low mr phosphotyrosine protein phosphatase behaves differently when phosphorylated at tyr131 or tyr132 by src kinase.. FEBS LETTERS, vol. 456, pp. 73-78, ISSN:0014-5793

P. Bettini; P. Chiarugi; M. Buiatti (1998). An in vitro molecular study of Nicotiana tabacum L. genome in the presence or absence of the herbicide atrazine.. THEORETICAL AND APPLIED GENETICS, vol. 96, pp. 242-250, ISSN:0040-5752 DOI Accesso ONLINE all'editore

P. Chiarugi; P. Cirri; F. Marra; G. Raugei; T. Fiaschi; G. Camici; G. Manao; RG. Romanelli; G. Ramponi (1998). The src and signal transducers and activators of transcription pathways as specific targets for low molecular weight phosphotyrosine-protein phosphatase in platelet-derived growth factor signaling. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, pp. 6776-6785, ISSN:0021-9258 Accesso ONLINE all'editore

P. Cirri; Chiarugi P; Taddei L; Raugei G; Camici G; Manao G; Ramponi G. (1998). Low molecular weight protein-tyrosine phosphatase tyrosine phosphorylation by c-Src during platelet-derived growth factor-induced mitogenesis correlates with its subcellular targeting.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, pp. 32522-32527, ISSN:0021-9258 Accesso ONLINE all'editore

M. Parola;G. Robino; F. Marra; M. Pinzani; G. Bellomo; G. Leonarduzzi; P. Chiarugi; P. Gentilini; M. Dianzani (1998). HNE interacts directly with JNK isoforms in human hepatic stellate cells. THE JOURNAL OF CLINICAL INVESTIGATION, vol. 102, pp. 1942-1950, ISSN:0021-9738

P.Chiarugi; D.Degl'Innocenti; L.Taddei; G.Raugei; A.Berti; S.Rigacci; G.Ramponi (1997). Acylphosphatase is involved in differentiation of K562 cells. CELL DEATH AND DIFFERENTIATION, vol. 4, pp. 334-340, ISSN:1350-9047

P Chiarugi; D Degl'Innocenti; G Raugei; T Fiaschi; G Ramponi (1997). Differential migration of acylphosphatase isoenzymes from cytoplasm to nucleus during apoptotic cell death.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 231, pp. 717-721, ISSN:0006-291X Accesso ONLINE all'editore

G.Raugei; P.Chiarugi; D.Degl'Innocenti; A.Berti; L.Taddei; S.Rigacci; G.Ramponi (1997). Possible role of both isoforms of acylphosphatase in differentiation and apoptosis in k562 cells. In: SIB 1997, pp. 85-86.

Chiarugi P; Cirri P; Marra F; Raugei G; Camici G; Manao G; Ramponi G (1997). LMW-PTP is a negative regulator of insulin-mediated mitotic and metabolic signalling. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 238, pp. 676-682, ISSN:0006-291X DOI Accesso ONLINE all'editore

Cirri P; Chiarugi P; Marra F; Raugei G; Camici G; Manao G; Ramponi G. (1997). c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 239, pp. 493-497, ISSN:0006-291X DOI Accesso ONLINE all'editore

P. CIRRI; T. FIASCHI; P. CHIARUGI; G. CAMICI; G. MANAO; G. RAUGEI; G. RAMPONI (1996). The molecular basis of the differing kinetic behavior of the two low molecular mass phosphotyrosine protein phosphatase isoforms.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, pp. 2604-2607, ISSN:0021-9258

P. Chiarugi; G. Raugei; T.Fiaschi; L. Taddei; G. Camici; G. Ramponi (1996). Characterization of a novel nucleolytic activity of acylphosphatases. BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, vol. 40, pp. 73-81, ISSN:1039-9712 Accesso ONLINE all'editore

P. Chiarugi; P. Cirri; G. Raugei; G. Manao; L. Taddei; G. Ramponi (1996). Low M(r) phosphotyrosine protein phosphatase interacts with the PDGF receptor directly via its catalytic site. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 219, pp. 21-25, ISSN:0006-291X DOI Accesso ONLINE all'editore

A. Caselli; P. Chiarugi; G. Camici; G. Manao; G. Ramponi (1995). In vivo inactivation of phosphotyrosine protein phosphatases by nitric oxide.. FEBS LETTERS, vol. 374, pp. 249-252, ISSN:0014-5793 DOI Accesso ONLINE all'editore

P. CHIARUGI ; G. RAUGEI ; R. MARZOCCHINI; T. FIASCHI ; C. CICCARELLI ; A. BERTI ; G. RAMPONI (1995). Differential modulation of expression of the two acylphosphatase isoenzymes by thyroid hormone.. BIOCHEMICAL JOURNAL, vol. 311, pp. 567-573, ISSN:0264-6021, Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331: Accesso ONLINE all'editore

P. CHIARUGI ; P. CIRRI; G. RAUGEI ; G. CAMICI ; F. DOLFI ; A. BERTI ; G. RAMPONI (1995). PDGF receptor as a specific in vivo target for low M(r) phosphotyrosine protein phosphatase.. FEBS LETTERS, vol. 372, pp. 49-53, ISSN:0014-5793, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

T. FIASCHI ; G. RAUGEI ; R. MARZOCCHINI ; P. CHIARUGI ; P. CIRRI; G. RAMPONI (1995). Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase.. FEBS LETTERS, vol. 367, pp. 145-148, ISSN:0014-5793, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

N. Taddei; P. Chiarugi; P. Cirri; T. Fiaschi; M. Stefani; G. Camici; G. Raugei; G. Ramponi (1994). Aspartic-129 is an essential residue in the catalytic mechanism of the low M(r) phosphotyrosine protein phosphatase. FEBS LETTERS, vol. 350, pp. 328-332, ISSN:0014-5793 Accesso ONLINE all'editore

P. CHIARUGI ; P. CIRRI ; G. CAMICI ; G. MANAO ; T. FIASCHI ; G. RAUGEI ; G. CAPPUGI; G. RAMPONI (1994). The role of His66 and His72 in the reaction mechanism of bovine liver low-M(r) phosphotyrosine protein phosphatase.. BIOCHEMICAL JOURNAL, vol. 298, pp. 427-433, ISSN:0264-6021 Accesso ONLINE all'editore

P. CIRRI; P. CHIARUGI ; G. CAMICI ; G. MANAO ; G. RAUGEI ; G. CAPPUGI ; G. RAMPONI (1993). The role of Cys12, Cys17 and Arg18 in the catalytic mechanism of low-M(r) cytosolic phosphotyrosine protein phosphatase.. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 214, pp. 647-657, ISSN:0014-2956 Accesso ONLINE all'editore

P. CIRRI; P. CHIARUGI ; G. CAMICI ; G. MANAO ; L. PAZZAGLI ; A. CASELLI ; I. BARGHINI ; G. CAPPUGI ; G. RAUGEI ; G. RAMPONI (1993). The role of Cys-17 in the pyridoxal 5'-phosphate inhibition of the bovine liver low M(r) phosphotyrosine protein phosphatase.. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 1161, pp. 216-222, ISSN:0925-4439 DOI

P. CHIARUGI ; R. MARZOCCHINI ; G. RAUGEI ; L. PAZZAGLI ; A. BERTI ; G. CAMICI ; G. MANAO ; G. CAPPUGI; G. RAMPONI (1992). Differential role of four cysteines on the activity of a low Mr phosphotyrosine protein phosphatase. FEBS LETTERS, vol. 310, pp. 9-12, ISSN:0014-5793, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598: Accesso ONLINE all'editore

V. CHIARUGI; M. RUGGIERO; L. MAGNELLI; S. PACINI; F. PASQUALI; P. CHIARUGI (1991). Phosphorylative signal transduction from the cell membrane to the nucleus. BULLETIN OF MOLECULAR BIOLOGY AND MEDICINE, vol. 16, pp. 149-160, ISSN:0391-481X

P. Bettini; P. Chiarugi; P. Bogani; C. Simeti; E. Storti; M.G. Pellegrini; M. Buiatti (1989). DNA rearrangements and multiplicity changes in tobacco somaclones susceptible or tolerant to atrazine. In: XXXIII Convegno Società Italiana di Genetica Agraria (S.I.G.A.), Porto Conte, Alghero (SS), Italy, 23-26/10/1989, Società Italiana di Genetica Agraria (SIGA), vol. Atti XXXIII Convegno Società Italiana di Genetica Agraria (S.I.G.A.), pp. 150-150.