1) Corso Tecniche di selezione, mantenimento e manipolazione di cellule staminali: Giovedì ore 9-10

2) Corso Fisiopatologia cellulare e molecolare del trapianto d’organo e di tessuto: Giovedì ore 10-11

3) Corso Rigenerazione e ripristino delle funzionalità renali mediante l’utilizzo di cellule staminali: Giovedì ore 11-12

Elena Lazzeri
nata a Firenze il 6 Dicembre 1974.
Stato civile: coniugata

Formazione

-Febbraio 1999: Laurea in Scienze Biologiche presso la Facoltà di Scienze Matematiche Fisiche e Naturali dell’Università degli Studi di Firenze con la votazione 108/110.
Titoli e Borse di studio

-2000: Vincitrice di una borsa di studio “Fondazione Anna Villa Rusconi” con il progetto “Analisi del ruolo delle chemochine Interferon- inducile Protein (IP-10) e monokine Induced by Interferon- (Mig) e del loro recettore (CXCR3) nella patogenesi delle glomerulonefriti proliferative”. Seconda classificata su 110 candidati a livello nazionale.

-2001: Vincitrice di una borsa di studio triennale della Fondazione Italiana Ricerca sul Cancro (FIRC) per il progetto “Studio dei meccanismi funzionali alla base dell’effetto angiostatico delle chemochine IP-10/CXCL10, Mig/CXCL9, I-TAC/CXCL11 e PF4/CXCL4, attraverso l’identificazione di una nuova variante recettoriale del CXCR3 (CXCR3-B)”

-2003: Conseguita specializzazione in “Biochimica e Chimica Clinica” presso la facoltà di Medicina e Chirurgia dell’Università degli Studi di Firenze.

-2003: Vincitrice del concorso per ricercatore a tempo determinato presso il Dipartimento di Medicina Interna, Facoltà di Medicina e Chirurgia dell’Università degli Studi di Firenze, per l’attuazione del Progetto di Ricerca “Terapie con cellule staminali prelevate da soggetto adulto”.

-2005: Vincitrice del concorso per ricercatore a tempo indeterminato in Scienze Tecniche di Medicina di Laboratorio (Settore scientifico disciplinare MED46) presso il Dipartimento di Medicina Interna della Facoltà di Medicina e Chirurgia dell’Università degli Studi di Firenze.

Linee di ricerca

Le ricerche effettuate dalla Dott.ssa Elena Lazzeri hanno riguardato in particolare lo studio del ruolo delle chemochine e dei loro recettori nella patogenesi delle glomerulonefriti e delle reazioni di rigetto del trapianto renale. Ha inoltre effettuato studi sulla timopoiesi, sui linfociti T regolatori e sulla regolazione dell’angiogenesi. La Dott.ssa Lazzeri si è, inoltre, occupata dello studio di una nuova popolazione di cellule staminali nel sangue periferico, che rappresenta la fonte principale di progenitori endoteliali circolanti, finalizzata alla messa a punto di nuove strategie terapeutiche nei confronti delle malattie ischemiche e degenerative. Più recentemente, la Dott.ssa Lazzeri si è occupata dell’identificazione di una popolazione di cellule staminali multipotenti nel rene umano adulto, aprendo importanti prospettive per l’utilizzo delle cellule staminali nel trattamento dell’insufficienza renale acuta e cronica. Attualmente, la Dott.ssa Elena Lazzeri sta lavorando all’identificazione di quelli che sono i meccanismi molecolari che controllano la migrazione, la crescita e il differenziamento della popolazione di cellule staminali multipotenti del rene.
Impact Factor e Citation Index
-Impact factor totale 226,04
-Impact factor medio 8.37
-Numero di citazioni 993.

PERSONAL INFORMATION

Elena Lazzeri

Date of birth: 06/12/1974

ORCID ID: 0000-0002-9505-2115

EDUCATION

1999: Degree on Biological Sciences at the University of Florence.2003: Specialization in Biochemistry and Clinical Chemistry at the School of Medicine, University of Florence.

CURRENT POSITION

2017: Associate Professor in Technical Sciences of Laboratory Medicine (MED46) of the Human Health Medical School at the University of Florence and works at the Department of Experimental and Clinical Biomedical Sciences of Florence.

PREVIOUS POSITIONS

2003: Post-doctoral researcher at the Department of Internal Medicine, University of Florence with the project “Therapies with stem cells obtained from adult subject”.2005: Researcher in Technical Sciences of Laboratory Medicine (Scientific disciplinary sector MED46) at the Department of Internal Medicine of the Faculty of Medicine and Surgery of the University of Florence.

FELLOWSHIPS

2000: Winner of a fellowship of “Anna Villa Rusconi Foundation” with the project “Analysis of the role of Interferon-g inducible Protein (IP-10) and monokine Induced by Interferon-g (Mig) and their receptor (CXCR3) in the pathogenesis of proliferative glomerulonephritis” 2001: Winner of a three years-fellowship of “Associazione Italiana per la Ricerca sul Cancro”. (FIRC) with the project “Study of the mechanisms of the angiostatic effect of the chemokines  IP-10/CXCL10, Mig/CXCL9, I-TAC/CXCL11 and PF4/CXCL4, through interaction with a novel receptor variant of CXCR3 (CXCR3-B)”

PERSONAL INFORMATION

Elena Lazzeri

Date of birth: 06/12/1974

ORCID ID: 0000-0002-9505-2115

METRICS

Publications: 76

H-Index: 43 (Scopus)

Total citations: 8156 (Scopus)

Scientific track-record: Elena Lazzerihas published 76 original manuscripts and reviews in international peer-reviewed journals. Her h-index is 43 (Scopus) with 8156 total citations.

She is invited speaker at national and international meetings.

She has a solid expertise in the field of Nephrology Research. Of note, she contributed to identify renal progenitors in adult human kidney. She has characterized the renal progenitor system in adult human kidney and demonstrated its capacity to generate novel podocytes as well as tubular cells of different portions of the nephron, leading to the description of the kidney progenitor system, in human. The discovery of the renal progenitor system has established an entirely novel view that is changing the way of thinking the renal physiology and pathophysiology. More recently, she demonstrated the existence of two response mechanisms, which act synergistically to promote the recovery of renal function after an acute kidney injury: 1. proliferation of renal progenitors; 2. an increase of tubular epithelial cell ploidy. Whereas renal progenitors play an important role in the regeneration of injured tubule segments, an increased tubular epithelial cell ploidy plays a crucial role to sustain the kidney function after an acute kidney injury. However, polyploidization of tubular cells in the long run promotes fibrosis and acute kidney injury-chronic kidney disease transition. Elena Lazzeri has also established and patented a method for selection and identification of renal progenitors from the urine of patients affected by kidney disorders. This method may allow personalized modelling of kidney disorder and be extremely useful to complement genetic diagnosis of inherited kidney disorders.

EDUCATION1999: Degree on Biological Sciences at the University of Florence.2003: Specialization in Biochemistry and Clinical Chemistry at the School of Medicine, University of Florence.

CURRENT POSITION2017: Associate Professor in Technical Sciences of Laboratory Medicine (MED46) of the Human Health Medical School at the University of Florence and works at the Department of Experimental and Clinical Biomedical Sciences of Florence.

PREVIOUS POSITIONS2003: Post-doctoral researcher at the Department of Internal Medicine, University of Florence with the project “Therapies with stem cells obtained from adult subject”.2005: Researcher in Technical Sciences of Laboratory Medicine (Scientific disciplinary sector MED46) at the Department of Internal Medicine of the Faculty of Medicine and Surgery of the University of Florence.

FELLOWSHIPS

2000: Winner of a fellowship of “Anna Villa Rusconi Foundation” with the project “Analysis of the role of Interferon-g inducible Protein (IP-10) and monokine Induced by Interferon-g (Mig) and their receptor (CXCR3) in the pathogenesis of proliferative glomerulonephritis”2001: Winner of a three years-fellowship of “Associazione Italiana per la Ricerca sul Cancro”. (FIRC) with the project “Study of the mechanisms of the angiostatic effect of the chemokines  IP-10/CXCL10, Mig/CXCL9, I-TAC/CXCL11 and PF4/CXCL4, through interaction with a novel receptor variant of CXCR3 (CXCR3-B)”

TEACHING ACTIVITIES

-In 2005 she is teacher in “Stem cell biology and regeneration”, “Cellular and molecular transplant pathophysiology”, “Renal function regeneration and restoration through the use of stem cells” at School of Biotechnology, University of Florence.

-In 2013/2014, she carries out didactic activities in the integrated course of "Pathological Anatomy and Histopathology-Diagnostic Techniques", within the Degree Course in Biomedical Laboratory Techniques, School of Human Health Sciences, University of Florence.

-Starting from the academic year 2018/2019, she carries out didactic activities in the integrated course of "Clinical Microbiology- Diagnostic Methods”, within the Degree Course in Biomedical Laboratory Techniques, School of Human Health Sciences, University of Florence.

-Starting from the 2013/2014 academic year, she is a teacher at the School of Specialization of Nephrology and Allergology and Immunology, School of Human Health Sciences, University of Florence.

-Starting from the 2019/2020 academic year, she is a teacher at the School of Specialization of Clinical Biochemistry and clinical Pathology and Anatomic Pathology, School of Human Health Sciences, University of Florence.

- Starting from the academic year 2005/06, she carried out exams of profit, followed by degree thesis, also acting as a speaker and / or co-supervisor in the aforementioned Degree Courses.

-She is a member of the Council of the School of Specialization of Nephrology and Allergology and Immunology.

ACTIVITIES IN HOSPITAL CARE

From 2005: she works at SOD of Immunology and Cellular Therapies of the Careggi University Hospital, where she performs the diagnostic of autoimmune organo specific diseases (indirect immunfluorescence on tissues and organs) and the diagnostic of renal diseases (indirect immunofluorescence on kidney biopsies).

From 2023: she works at SOD of DIAGNOSTIC CENTER OF CYTOFLUORIMETRY AND IMMUNOTHERAPY of the Careggi University Hospitalwith an interdipartimental collaboration, where she performs the diagnostic of autoimmune diseases (indirect immunfluorescence ANA and tissue and organ assays) and the diagnostic of renal diseases (indirect immunofluorescence on kidney biopsies).

TRAINING COURSES:

2019: EMBO/FEBS Lecture Course Molecular mechanisms of tissue injury, repair and fibrosis. 23-31 May 2019, Spetses island, Greece.

2014:   Leica advanced course in confocal microscopy, Milan, Italy. One week theoretical and practical course.

2016: Evento formativo accreditato a livello regionale n°903201650357 denominato Prevenzione della corruzione trasparenza e integrità: il codice etico e di comportamento aziendale-II ciclo

2016: Evento formativo accreditato a livello regionale n°9032016550103 denominato Rischio biologico.

2016: Evento formativo accreditato a livello regionale n°9032016050061 denominato Rischio chimico.

2017: Evento formativo accreditato a livello regionale n°9032017052797 denominato Rischio chimico-gas medicinali, bombole e azoto liquido.

2017: Corso Azienda Ospedaliero Universitaria Careggi n. 9032017053668, Utilizzo degli autorespiratori.

2020:“Rischi comuni a tutte le mansioni” del corso di “Formazione specifica dei lavoratori del Dipartimento di Scienze Biomediche, Sperimentali e Cliniche in materia di salute e sicurezza ai sensi dell'Accordo Stato Regioni del 21.12.2011”.

2020:“Attrezzature” del corso di “Formazione specifica dei lavoratori del Dipartimento di Scienze Biomediche, Sperimentali e Cliniche in materia di salute e sicurezza ai sensi dell'Accordo Stato Regioni del 21.12.2011”.

2020:“ROA e CEM” del corso di “Formazione specifica dei lavoratori del Dipartimento di Scienze Biomediche, Sperimentali e Cliniche in materia di salute e sicurezza ai sensi dell'Accordo Stato Regioni del 21.12.2011”.

PATENTS

Lazzeri E, Lasagni L, Romagnani P. Method fo the isolation, purification and amplification of renal progenitors from the urine of patients with kidney disorders. Azienda Ospedaliero Universitaria Meyer. FI2013A000303 del 24/12/2013 patent number 0001421589.

ORGANISATION OF SCIENTIFIC MEETINGS

2018: Scientific committee of 30th Meeting of European Renal Cell Study Group, 19-22 aprile 2018, Artimino, Prato.

INVITED SPEAKER

-64°Congresso della Società Italiana di Nefrologia, 4-7 ottobre 2023, Torino. “I progenitori renali derivati dalle urine: un bene prezioso da tesorizzare”.

-30th Meeting of European Renal Cell Study Group, 19-22 aprile 2018, Artimino, Prato.  “Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury”.

-VIII meeting SCRI: Chieti 25-27 maggio 2017. “Kidney stem cells and their therapeutical potential”.

-First Consensus Meeting on Renal Progenitors and Kidney Regeneration, 10-12 giugno 2016, Florence.

-56° Congresso Nazionale della Società Italiana di Nefrologia, 1-4 ottobre 2015, Rimini. “Podocitopatie: alla ricerca di nuovi strumenti di indagine”.

-54° Congresso Nazionale della Società Italiana di Nefrologia, 25-28 settembre 2013, Firenze. “Progenitori renali: dalle urine dei pazienti all’utilizzo clinico”.

-Cinquantenario della dialisi in Italia, 25 novembre 2011, Pescara. “Cellule staminali e rene”.

-52° Congresso Nazionale della Società Italiana di Nefrologia, 21-24 settembre 2011, Genova. “Ruolo dei progenitori renali nella rigenerazione tubulare”.

-Giornate Nefrologiche in Versilia, 5-6 maggio 2011, Lido di Camaiore. “Stem cells in glomerular diseases”.

-51° Congresso Nazionale della Società Italiana di Nefrologia. 6-9 ottobre 2010, Rimini. “La Real-Time PCR”.

-49° Congresso Nazionale della Società Italiana di Nefrologia. 8-11 ottobre 2008, Rimini. “Nuove tecniche di microdissezione e microscopia”.

Other oral comunications:

-60°ERA CONGRESS, Milan 15-18 June 2023. “Kidney tubule polyploidization during physiologic ageing in mice”.

-Polyploidy Conference, Palm Coast, Florida, 9-12 may 2023. “Kidney tubule polyploidization during physiologic ageing in mice”.

-35th Meeting of the European Renal Cell Study Group. Noordwijkerhout, The Netherlands, 30 marzo -1 aprile 2023. “Polyploid tubular cells initiate a TGF-β controlled loop that sustains polyploidization and fibrosis during AKI-CKD transition”.

-29th Meeting of the European Renal Cell Study Group, GÖTTINGEN, GERMANY

APRIL 27TH - 30TH 2017. “Tubular cell endocycle and progenitor proliferation rescue acute kidney injury despite persistent tubular cell loss”.

-Kidney Week: 50th Annual Meeting, New Orleans 1-5 November 2017:“Endocycle-mediated hypertrophy and progenitor proliferation as central mechanisms of response to acute injury”.

- Kidney Week: 49th Annual Meeting, Chicago 15-20 November 2016:“Tubular Cell Endocycle-Related Hypertrophy and Renal Progenitor Mitosis Drive Kidney Function Recovery After AKI But Cannot Avoid Persistent Tubular Cell Loss”.

-28th Meeting of the European Renal Cell Study Group, Chantilly, Paris 21-24 april 2016:“Tubular progenitors drive repair following acute kidney injury despite an irreversible tubular cell loss occurs”.

-Kidney Week: 48th Annual Meeting, San Diego 3-8 November 2015:“Tubular Regeneration after Acute Kidney Injury is limited and only driven by Tubular Progenitors”.

-26th Meeting of the European Renal Cell Study Group, Regensburg 27-30 march 2014:“Urine-derived human renal progenitor cultures for modeling of genetic kidney disorders”.

-Academy of Ideas, Ariano Irpino, 1-3 September 2014: “Urine-derived human renal progenitors for the functional diagnosis and disease modeling of genetic kidney disorders”.

-47th Annual Scientific Meeting of the European Society for Paediatric Nephrology, Porto 18-20 september 2014:“Urine-derived human renal progenitor cultures for modeling of genetic kidney disorders”.

-ISN Forefronts Symposium 2013. Stem Cells and Kidney Regeneration, Florence 12-15 september 2013:“Isolation and characterization of urine-derived renal progenitors from pediatric patients affected by glomerular diseases”.

-KIDSTEM INTERNATIONAL CONFERENCE, Liverpool 17–19 september 2008:“Regeneration of glomerular podocytes by human renal progenitors”.

-49° Congresso Nazionale della Società Italiana di Nefrologia, Rimini 8-11 ottobre 2008:“Ruolo dei recettori chemochinici CXCR4 e CXCR7 nella migrazione e nella capacità rigenerativa delle cellule staminali renali in modelli murini di insufficienza renale acuta”.

-Primo incontro con la giovane nefrologia, Roma 30 ottobre 1 novembre 2006:“Isolation and characterization of multipotent stem cells from the Bowman’s capsule of adult human kidneys”.

-47° Congresso Nazionale della Società Italiana di Nefrologia, Roma 24-27 maggio 2006:“Isolamento e caratterizzazione di cellule staminali multipotenti dalla capsula di Bowman di reni umani adulti”.

-GIORNATE NEFROLOGICHE ROMANE Remissione e regressione del danno renale. Roma, 19-21 febbraio 2004:“ELEVATI LIVELLI DI ESPRESSIONE DI IP-10/CXCL10, MIG/CXCL9, I-TAC/CXCL11, PF4/CXCL4 E DEL LORO RECETTORE CXCR3-B NEL RIGETTO ACUTO E NELLA NEFROPATIA CRONICA DA TRAPIANTO. RUOLO FUNZIONALE DEL CXCR3-B ESPRESSO DALLE CELLULE EPITELIALI DEL TUBULO PROSSIMALE”.

EDITORIAL ACTIVITY

Evaluator CINECA VQR 2011-2014.

2018: Review Editor of the journal Frontiers, section Renal Pharmacology.

2020: Associate Editor of the journal Frontiers, section Renal Pharmacology.

GRANTS

2023-2025: Principal Investigator of PRIN: PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE – Bando 2022 PNRR, with the study titled “AGING AND DECLINE OF RENAL PROGENITOR REGENERATIVE CAPACITY: IDENTIFICATION OF MOLECULAR MECHANISMS AND

ANTI-SENESCENT MOLECULES AS THERAPEUTIC TREATMENTS FOR CKD”.

2023-2025: Coordinator of PRIN: PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE – Bando 2022, with the study titled “Tubular epithelial cell polyploidy in MYH9-related disease nephropathy”.

2022-2025: Principal investigator of the Research Unit in the European project ERA PerMed JTC2021, with the study titled “Implementation of personalised management in nephrotic syndrome" acronym PER-NEPH.

2020-2023: Principal investigator of the Research Unit of Azienda Ospedaliero Universitaria Careggi (AOUC) in the national project Bando Ricerca Salute 2018, with the study titled "Set-up of a platform for personalized diagnosis of rare kidney diseases" acronym NIKE.(AOUC Unit Funding Euro 110,000).

2008-2010: Principal investigator of the Research Unit of the national project PRIN / FIRB prot. 2008NY2B9T_002, with the study titled "Study of the role of chemokines CXCL9 and CXCL10 as predictors of chronic graft nephropathy".

2005-2007: Principal investigator of the Research Unit of the national project PRIN / FIRB prot. 2005068145_002, with the project entitled "Isolation and characterization of a multipotent human glomerular stem cell".

2021-2026: Participant in the European project ERC Advanced Investigator Grant-Horizon 2020: “Sexual dimorphIsM in renal PrOgenitors to explain gender-Specificity In kidney physiOlogy aNd diseases SIMPOSION.

2015-2019: Participant in the European project ERC Consolidator Grant ERC-2014 CoG-648274_Renoir. "Renal progenitors: Tools for modeling and targets for treatment of kidney disorders".

2012-2017: Participant in the European project European Cooperative Grant FP7, STELLAR, "Stem-cell based therapy for kidney repair" Grant number 305436.

2009-2011: Participant in the project of the Regional Health Research Program 2009 - Tuscany Region, "Renal stem cells amplification from the urine of patients with glomerular disorders for the set-up of autologous cell therapy of chronic renal injury".

2008-2012: Participant in the European ERC project Starting Grant Young Investigator Award, RESCARF, Renal stem cells: possible role in kidney pathologies and as new therapeutic tools. Grant number 205027.

2008-2011: Participant in the European project European Cooperative Grant Seventh Framework program theme-Health-2007-1.4-8 FP7 Program, STAR-T REK, Set up and comparison of multiple stem cell approaches for kidney repair. Grant number 223007.

2007-2009: Participant in the AIRC project "Renal cancer stem cells: isolation, characterization and comparison with normal renal stem cells".

BOOK CHAPTERS

-Angelotti ML, Lazzeri E, Romagnani P. Localization of Injury and Repair Pathways Critical Care Nephrology: Third Edition, 2019, pp. 173–178.e2

-Lasagni L, Lazzeri E, Peired A, Romagnani P. Kidney Development, Disease, Repair and Regeneration: Edited by Melissa Little, Elsevier 2015.

-Lazzeri E, Peired A, Ballerini L, Lasagni L. Adult stem cells in tissue homeostasis and disease: Current frontiers and perspectives in cell biology. Edited by Stevo Najmam, InTech, 2012

-Lasagni L, Lazzeri E, Romagnani P. Stem cell niche in the kidney: Regenerative nephrology; pg. 233-243; Edited by M Goligorsky. Elsevier, 2011.

PUBLICATIONS

1. De Chiara L, Semeraro R, Mazzinghi B, Landini S, Molli A, Antonelli G, Angelotti ML, Melica ME, Maggi L, Conte C, Peired AJ, Cirillo L, Raglianti V, Magi A, Annunziato F, Romagnani P, Lazzeri E. Polyploid tubular cells initiate a TGF-β1 controlled loop that sustains polyploidization and fibrosis after acute kidney injury. Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C849-C861. (I.F. 5.2)
2. Melica ME, Angelotti ML, Antonelli G, Peired AJ, Conte C, De Chiara L, Mazzinghi B, Lazzeri E, Lasagni L, Romagnani P. Preparation of Human Kidney Progenitor Cultures and Their Differentiation into Podocytes. Bio Protoc. 2023 Aug 20;13(16):e4757. (I.F.0.7)
3. Becherucci F, Landini S, Palazzo V, Cirillo L, Raglianti V, Lugli G, Tiberi L, Dirupo E, Bellelli S, Mazzierli T, Lomi J, Ravaglia F, Sansavini G, Allinovi M, Giannese D, Somma C, Spatoliatore G, Vergani D, Artuso R, Rosati A, Cirami C, Dattolo PC, Campolo G, De Chiara L, Papi L, Vaglio A, Lazzeri E, Anders HJ, Mazzinghi B, Romagnani P. A Clinical Workflow for Cost-Saving High-Rate Diagnosis of Genetic Kidney Diseases. J Am Soc Nephrol. 2023 Jan 17. (I.F. 14.978).
4. De Chiara L, Conte C, Semeraro R, Diaz-Bulnes P, Angelotti ML, Mazzinghi B, Molli A, Antonelli G, Landini S, Melica ME, Peired AJ, Maggi L, Donati M, La Regina G, Allinovi M, Ravaglia F, Guasti D, Bani D, Cirillo L, Becherucci F, Guzzi F, Magi A, Annunziato F, Lasagni L, Anders HJ, Lazzeri E†, Romagnani P†. † contributed equally. Tubular cell polyploidy protects from lethal acute kidney injury but promotes consequent chronic kidney disease. Nat Commun. 2022 Oct 4;13(1):5805. (I.F. 17.694).
5. Melica ME, Antonelli G, Semeraro R, Angelotti ML, Lugli G, Landini S, Ravaglia F, La Regina G, Conte C, De Chiara L, Peired AJ, Mazzinghi B, Donati M, Molli A, Steiger S, Magi A, Bartalucci N, Raglianti V, Guzzi F, Maggi L, Annunziato F, Burger A, Lazzeri E, Anders HJ, Lasagni L,† and Romagnani P,†. † contributed equally. Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice. Sci Transl Med 2022 Aug 10;14(657):eabg3277. (I.F. 17.161).
6. De Chiara L, Lugli G, Villa G, Raglianti V, Husain-Syed F, Ravaglia F, Romagnani P, Lazzeri E. Molecular Mechanisms and Biomarkers Associated with Chemotherapy-Induced AKI. Int J Mol Sci. 2022 Feb 27;23(5):2638. (I.F. 5.923).
7. De Chiara L, Conte C, Antonelli G, Lazzeri E. Tubular cell cycle response upon AKI: revising old and new paradigms to identify novel targets for CKD prevention. Int J Mol Sci, 2021 Oct 14;22(20):11093. (I.F. 5.923).
8. Peired AJ, Campi R, Angelotti ML, Antonelli G, Conte C, Lazzeri E, Becherucci F, Calistri L, Serni S, Romagnani P. Sex and Gender Differences in Kidney Cancer: Clinical and Experimental Evidence. Cancers 2021 Sep 13;13(18):4588. (I.F. 6.639).
9. Peired AJ, Lazzeri E, Guzzi F, Anders HJ, Romagnani P. From Kidney Injury to Kidney Cancer. Kidney International 2021, Jul;100(1):55-66. (I.F. 8.395).
10. Peired AJ, Antonelli G, Angelotti ML, Allinovi M, Guzzi F, Sisti A, Semeraro R, Conte C, Mazzinghi B, Nardi S, Melica ME, De Chiara L, Lazzeri E, Lasagni L, Lottini T, Landini S, Giglio S, Mari A, Di Maida F, Antonelli A, Porpiglia F, Schiavina R, Ficarra V, Facchiano D, Gacci M, Serni S, Carini M, Netto1 GJ, Roperto RM, Magi A, Christiansen CF, Rotondi M, Liapis H, Anders HJ, Minervini A, Raspollini MR, Romagnani P. Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells. Sci Transl Med. 2020 Mar 25;12(536):eaaw6003. (I.F. 17.161).
11. Peired AJ, Mazzinghi B, De Chiara L, Guzzi F, Lasagni L, Romagnani P, Lazzeri E. Bioengineering strategies for nephrologists: kidney was not built in a day. Expert Opin Biol Ther. 2020 Jan 23:1-14. (I.F. 3.974).
12. Guzzi F, Cirillo L, Roperto RM, Romagnani P, Lazzeri E. Molecular Mechanisms of the Acute Kidney Injury to Chronic Kidney Disease Transition: An Updated View. Int J Mol Sci. 2019 Oct 6;20(19). pii: E4941. (I.F. 5.923).

1. Lazzeri E, Angelotti ML, Conte C, Anders HJ, Romagnani P. Surviving Acute Organ Failure: Cell Polyploidization and Progenitor Proliferation. Trends Mol Med. 2019 Mar 26. pii: S1471-4914(19)30041-3. (I.F. 11.021).
2. Manonelles A, Guiteras R, Melilli E, Lazzeri E, Goma M, Crespo E, Bestard O, Sola A, Romagnani P, Cruzado JM. The Presence of Urinary Renal Progenitor Cells in Stable Kidney Transplant Recipients Anticipates Allograft Deterioration. Front Physiol. 2018 Oct 10;9:1412. (I.F.3.92).
3. Elena Lazzeri, Maria Lucia Angelotti, Anna Peired, Carolina Conte, Julian A. Marschner, Laura Maggi, Benedetta Mazzinghi, Duccio Lombardi, Maria Elena Melica, Sara Nardi, Elisa Ronconi, Alessandro Sisti, Giulia Antonelli, Francesca Becherucci, Ricardo Romero Guevara, Alexa Burger, Beat Schaefer, Francesco Annunziato, Hans-Joachim Anders, Laura Lasagni, Paola Romagnani. Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury. Nat Comm. 2018 Apr 9;9(1):1344. (I.F.12.12).
4. Benedetta Mazzinghi, Paola Romagnani, Elena Lazzeri. Biologic modulation in renal regeneration. Expert Opin Biol Ther. 2016 Nov;16(11):1403-1415. (I.F. 3.743).
5. Paola Romagnani, Sabrina Giglio, Maria Lucia Angelotti, Aldesia Provenzano, Francesca Becherucci, Benedetta Mazzinghi, Susanna Müller, Kerstin Amann, Marc Weidenbusch, Simone Romoli, Elena Lazzeri, Hans-Joachim Anders. A genetic cause of refractory lupus nephritis diagnosed by next generation sequencing and functional analysis of patient-derived podocytes. Nephrol Dial Transplant. 2016 Sep;31(9):1541-5. (I.F. 3.577).
6. Lasagni L, Angelotti ML, Ronconi E, Lombardi D, Nardi S, Peired A, Becherucci F, Mazzinghi B, Sisti A, Romoli S, Burger A, Schaefer B, Buccoliero A, Lazzeri E, Romagnani P. Podocyte Regeneration Driven by Renal Progenitors Determines Glomerular Disease Remission and Can Be Pharmacologically Enhanced. Stem Cell Reports. 2015 Aug 11;5(2):248-63.(I.F. 5)
7. Becherucci F, Lazzeri E, Romagnani P. A Road to Chronic Kidney Disease: Toward Glomerulosclerosis via Dendrin. Am J Pathol. 2015 Aug;185(8):2072-5. (I.F. 6.750)
8. Lazzeri E, Lasagni L. Stem cell therapies in kidney disease. Expert Opin Biol Ther. 2015 Oct;15(10):1455-68.(I.F. 3.743)
9. Lazzeri E, Ronconi E, Angelotti ML, Peired A, Mazzinghi B, Becherucci F, Conti S, Sansavini G, Sisti A, Ravaglia F, Lombardi D, Provenzano A, Manonelles A, Cruzado JM, Giglio S, Roperto RM, Materassi M, Lasagni L, Romagnani P. Human Urine-Derived Renal Progenitors for Personalized Modeling of Genetic Kidney Disorders. J Am Soc Nephrol. 2015 Jan 7. (I.F. 9.663)
10. Lazzeri E, Romagnani P. Podocyte biology: Differentiation of parietal epithelial cells into podocytes. Nat Rev Nephrol. 2015 Jan;11(1):7-8. doi: 10.1038/nrneph.2014.218. (I.F.8.368)
11. Giglio S, Provenzano A, Mazzinghi B, Becherucci F, Giunti L, Sansavini G, Ravaglia F, Roperto RM, Farsetti S, Benetti E, Rotondi M, Murer L, Lazzeri E, Lasagni L, Materassi M, Romagnani P. Heterogeneous genetic alterations in sporadic nephrotic syndrome associate with resistance to immunosuppression. J Am Soc Nephrol. 2015 Jan;26(1):230-6. (I.F. 9.663)
12. Lazzeri E, Peired AJ, Lasagni L, Romagnani P. Retinoids and glomerular regeneration. Semin Nephrol. 2014 Jul;34(4):429-36. (I.F. 3.773).
13. Peired A, Lazzeri E, Lasagni L, Romagnani P. Glomerular regeneration: when can the kidney regenerate from injury and what turns failure into success? Nephron Exp Nephrol. 2014;126(2):70.(I.F. 1.649)
14. Becherucci F, Lazzeri E, Lasagni L, Romagnani. Renal progenitors and childhood: from development to disorders. Pediatr Nephrol. 2014 Apr;29(4):711-9. (I.F. 2.881)
15. Peired A, Angelotti ML, Ronconi E, la Marca G, Mazzinghi B, Sisti A, Lombardi D, Giocaliere E, Della Bona M, Villanelli F, Parente E, Ballerini L, Sagrinati C, Wanner N, Huber TB, Liapis H, Lazzeri E, Lasagni L, Romagnani P. Proteinuria Impairs Podocyte Regeneration by Sequestering Retinoic Acid. J Am Soc Nephrol. 2013 Aug 15. (I.F.9.663)
16. Mulay SR, Thomasova D, Ryu M, Kulkarni OP, Migliorini A, Bruns H, Gröbmayr R, Lazzeri E, Lasagni L, Liapis H, Romagnani P, Anders HJ. Podocyte loss involves MDM2-driven mitotic catastrophe. J Pathol. 2013 Jul;230(3):322-35. (I.F. 7.585)
17. Lasagni L, Lazzeri E, Shankland SJ, Anders HJ, Romagnani P. Podocyte mitosis - a catastrophe. Curr Mol Med. 2013 Jan;13(1):13-23 (I.F. 4.476).
18. Angelotti ML, Ronconi E, Peired A, Mazzinghi B, Lazzeri E, Lasagni L, Romagnani P. Tubular progenitor cells: new protagonists of tubular regeneration. G Ital Nefrol. 2012 Sep-Oct;29(5):514-8.
19. Macconi D, Tomasoni S, Romagnani P, Trionfini P, Sangalli F, Mazzinghi B, Rizzo P, Lazzeri E, Abbate M, Remuzzi G, Benigni A. MicroRNA-324-3p Promotes Renal Fibrosis and Is a Target of ACE Inhibition. J Am Soc Nephrol. 2012 Jul 19. (I.F. 9.663)
20. Angelotti ML, Ronconi E, Ballerini L, Peired A, Mazzinghi B, Sagrinati C, Parente E, Gacci M, Carini M, Rotondi M, Fogo AB, Lazzeri E, Lasagni L, Romagnani P. Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Stem Cells. 2012 Aug;30(8):1714-25. (I.F. 7.781)
21. Angelotti ML, Lazzeri E, Lasagni L, Romagnani P. Only anti-CD133 antibodies recognizing the CD133/1 or the CD133/2 epitopes can identify human renal progenitors. Kidney Int. 2010 Sep;78(6):620-1.(I.F. 6.606)
22. Lasagni L, Ballerini L, Angelotti mL, Parente E, Sagrinati C, Mazzinghi B, Peired A, Ronconi E, Becherucci F, Bani D, Gacci M, Carini M, Lazzeri E, Romagnani P. Notch activation regulates differentially renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders. Stem Cells 2010 Sep;28(9):1674-85.(I.F. 7.741)
23. Lazzeri E, Mazzinghi B, Romagnani P. Regeneration and the kidney. Curr Opin Nephrol Hypertens. 2010 May;19(3):248-53.(I.F.4)
24. Rotondi M, Netti GS, Lazzeri E, Stallone G, Bertoni E, Chiovato L, Grandaliano G, Gesualdo L, Salvadori M, Schena FP, Romagnani P, Serio M High pretransplant serum levels of CXCL9 are associated with increased risk of acute rejection and graft failure in kidney graft recipients. Transpl Int. 2010 May 1;23(5):465-75. Epub 2009 Nov 19.(I.F.3.115)
25. Ronconi E, Mazzinghi B, Sagrinati C, Angelotti ML, Ballerini L, Parente E, Romagnani P, Lazzeri E, Lasagni L. [The role of podocyte damage in the pathogenesis of glomerulosclerosis and possible repair mechanisms.]G Ital Nefrol. 2009 Nov-Dec;26(6):660-9.
26. Pelletier M, Maggi L, Micheletti A, Lazzeri E, Tamassia N, Costantini C, Cosmi L, Lunardi C, Annunziato F, Romagnani S, Cassatella MA Evidence for a cross-talk between human neutrophils and Th17 cells. Blood. 2010 Jan 14;115(2):335-43.(I.F. 10.432).
27. Smeets B, Angelotti ML, Rizzo P, Dijkman H, Lazzeri E, Mooren F, Ballerini L, Parente E, Sagrinati C, Mazzinghi B, Ronconi E, Becherucci F, Benigni A, Steenbergen E, Lasagni L, Remuzzi G, Wetzels J, Romagnani P. Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. J Am Soc Nephrol. 2009 Dec;20(12):2593-603. (I.F. 7.505)
28. Becherucci F, Mazzinghi B, Ronconi E, Peired A, Lazzeri E, Sagrinati C, Romagnani P, Lasagni L. The role of endothelial progenitor cells in acute kidney injury. Blood Purif. 2009;27(3):261-70. (I.F. 1.748)
29. Ronconi E, Sagrinati C, Angelotti ML, Lazzeri E, Mazzinghi B, Ballerini L, Parente E, Becherucci F, Gacci M, Carini M, Maggi E, Serio M, Vannelli GB, Lasagni L, Romagnani S, Romagnani P. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol. 2008 in press. (I.F. 7.505). F1000 rating of 6.4: “Must read. Paper of general interest containing a new finding”.
30. E.Lazzeri, M.L.Angelotti, L.Ballerini, F.Becherucci, B.Mazzinghi, E.Parente, E.Ronconi, C.Sagrinati, P.Romagnani, L.Lasagni. Ruolo dei progenitori endoteliali nelle malattie renali. G Ital Nefrol. 2008 in press.
31. S. Gelmini, M. Mangoni, M. Serio, P.Romagnani, E. Lazzeri.The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis. Journal of Endocrinological Investigation 2008 (I.F.2,021).
32. Sagrinati C, Ronconi E, Lazzeri E, Lasagni L, Romagnani P. Stem-cell approaches for kidney repair: choosing the right cells. Trends Mol Med. 2008 Jun 11(I.F.5,9).
33. Mazzinghi B, Ronconi E, Lazzeri E, Sagrinati C, Ballerini L, Angelotti ML, Parente E, Mancina R, Netti GS, Becherucci F, Gacci M, Carini M, Gesualdo L, Rotondi M, Maggi E, Lasagni L, Serio M, Romagnani S, Romagnani P Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells. J Exp Med. 2008 Feb 18;205(2):479-90. (I.F. 14,484)
34. Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F, Rodolico G, Querci V, Abbate G, Angeli R, Berrino L, Fambrini M, Caproni M, Tonelli F, Lazzeri E, Parronchi P, Liotta F, Maggi E, Romagnani S, Annunziato F. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J Exp Med. 2008 Aug 4;205(8):1903-16.(I.F. 14,484)
35. Lazzeri E, Crescioli C, Ronconi E, Mazzinghi B, Sagrinati C, Netti GS, Angelotti ML, Parente E, Ballerini L, Cosmi L, Maggi L, Gesualdo L, Rotondi M, Annunziato F, Maggi E, Lasagni L, Serio M, Romagnani S, Vannelli GB, Romagnani P. Regenerative potential of embryonic renal multipotent progenitors in acute renal failure. J Am Soc Nephrol. 2007 Dec;18(12):3128-38. (I.F. 7.505)
36. Romagnani P, Lasagni L, Mazzinghi B, Lazzeri E, Romagnani S. Pharmacological modulation of stem cell function. Curr Med Chem. 2007;14(10):1129-39. Review.(I.F. 5.207)
37. Mazzinghi B, Netti GS, Lazzeri E, Romagnani P. Chemokines: possible therapeutic targets and useful clinical parameters in renal transplantation. G Ital Nefrol. 2007 May-Jun;24(3):212-20
38. Lasagni L, Grepin R, Mazzinghi B, Lazzeri E, Meini C, Sagrinati C, Liotta F, Frosali F, Ronconi E, Alain-Courtois N, Ballerini L, Netti GS, Maggi E, Annunziato F, Serio M, Romagnani S, Bikfalvi A, Romagnani P. PF-4/CXCL4 and CXCL4L1 exhibit distinct subcellular localization and a differentially regulated mechanism of secretion. Blood. 2007 May 15;109(10):4127-34. (I.F. 10.432).
39. Lazzeri E, Netti GS, Mazzinghi B, Cirami C, Salvadori M, Romagnani P. A young woman with oedema. Intern Emerg Med. 2006;1(3):209-15. (I.F. 2.410).
40. Sagrinati C, Netti GS, Mazzinghi B, Lazzeri E, Liotta F, Frosali F, Ronconi E, Meini C, Gacci M, Squecco R, Carini M, Gesualdo L, Francini F, Maggi E, Annunziato F, Lasagni L, Serio M, Romagnani S, Romagnani P. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J Am Soc Nephrol 17:2443-2456, 2006. (I.F. 7.505)
41. Annunziato F, Cosmi L, Liotta F, Lazzeri E, Romagnani P, Angeli R, Lasagni L, Manetti R, Marra F, Gerard C, Petrai I, Dello Sbarba P, Tonelli F, Maggi E, Romagnani S. CXCR3 and alphaEbeta7 integrin identify a subset of CD8+ mature thymocytes that share phenotypic and functional properties with CD8+ gut intraepithelial lymphocytes. Gut. 2006 Jul;55(7):961-8. (I.F. 9,002)
42. Romagnani P, Maggi L, Mazzinghi B, Cosmi L, Lasagni L, Liotta F, Lazzeri E, Angeli R, Rotondi M, Fili L, Parronchi P, Serio M, Maggi E, Romagnani S, Annunziato F CXCR3-mediated opposite effects of CXCL10 and CXCL4 on TH1 or TH2 cytokine production.J Allergy Clin Immunol. 2005 Dec;116(6):1372-9. (I.F. 8,829)
43. Romagnani P, Lazzeri E, Mazzinghi B, Lasagni L, Guidi S, Bosi A, Cirami C, Salvadori M. Nephrotic syndrome and renal failure after allogeneic stem cell transplantation: novel molecular diagnostic tools for a challenging differential diagnosis. Am J Kidney Dis. 2005 Sep;46(3):550-6. (I.F. 4,072)
44. Romagnani P, Annunziato F, Liotta F, Lazzeri E, Mazzinghi B, Frosali F, Cosmi L, Maggi L, Lasagni L, Scheffold A, Kruger M, Dimmeler S, Marra F, Gensini G, Maggi E, Romagnani S. CD14+CD34low cells with stem cell phenotypic and functional features are the major source of circulating endothelial progenitors. Circ Res. 2005 Aug 19;97(4):314-22. (I.F. 9,354). F1000 rating of 6: “Must read. Paper of general interest containing a new finding and a technical advance”.
45. Pende D, Castriconi R, Romagnani P, Spaggiari GM, Marcenaro S, Dondero A, Lazzeri E, Lasagni L, Martini S, Rivera P, Capobianco A, Moretta L, Moretta A, Bottino C. Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction. Blood. 2006 Mar 1;107(5):2030-6. (I.F. 10.432).
46. Lazzeri E, Rotondi M, Mazzinghi B, Lasagni L, Buonamano A, Rosati A, Pradella F, Fossombroni V, La Villa G, Gacci M, Bertoni E, Serio M, Salvadori M, Romagnani P. High CXCL10 expression in rejected kidneys and predictive role of pretransplant serum CXCL10 for acute rejection and chronic allograft nephropathy. Transplantation. 2005 May 15;79(9):1215-20. (I.F. 3.972)
47. Rotondi M, Falorni A, De Bellis A, Laureti S, Ferruzzi P, Romagnani P, Buonamano A, Lazzeri E, Crescioli C, Mannelli M, Santeusanio F, Bellastella A, Serio M. Elevated serum interferon-gamma-inducible chemokine-10/CXC chemokine ligand-10 in autoimmune primary adrenal insufficiency and in vitro expression in human adrenal cells primary cultures after stimulation with proinflammatory cytokines. J Clin Endocrinol Metab. 2005 Apr;90(4):2357-63. (I.F. 5,799)
48. Lazzeri E., Romagnani P. CXCR3-binding chemokines: novel multifunctional therapeutic targets. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar;5(1):109-18. Review. (I.F. 4,274).
49. Rotondi M, Rosati A, Buonamano A, Lasagni L, Lazzeri E, Pradella F, Fossombroni V, Cirami C, Lotta F, La Villa G, Serio M, Bretoni E, Salvatori M, Romagnani P. “High pretransplant serum levels of CXCL10/IP-10 are related to increased risk of renal allograft failure”. Am J Transplant Sep;4(9):1466-74. (I.F. 4,940).
50. Orlando C, Raggi CC, Bianchi S, Simi L, Vezzosi V, Gelmini S, Pinzani P, Cameron Smith M, Buonamano A, Lazzeri E, Pazzagli M, Cataliotti L, Maggi M, Serio M. “Measurement of somatostatin receptor subtype 2 mRNA in breast cancer and corresponding normal tissue”. Endocr Relat Cancer. 2004 Jun;11(2):323-32.(I.F. 6.087).
51. Cosmi L, Liotta F, Lazzeri E, Francalanci M, Angeli R, Mazzinghi B, Santarlasci V, Manetti R, Vanini V, Romagnani P, Maggi E, Romagnani S, Annunziato F. “Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes.” Blood. 2003 Dec 1;102(12):4107-14.(I.F. 10.432).
52. Bonacchi A, Petrai I, Defranco RM, Lazzeri E, Annunziato F, Efsen E, Cosmi L, Romagnani P, Milani S, Failli P, Batignani G, Liotta F, Laffi G, Pinzani M, Gentilini P, Marra F. “The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.” Gastroenterology. 2003 Oct;125(4):1060-76. (I.F. 13,440).
53. Lasagni L., Francalanci M, Annunziato F, Lazzeri E, Giannini S, Cosmi L, Sagrinati C, Mazzinghi B, Orlando C, Maggi E, Marra F, Romagnani S, Serio M, and Romagnani P. “An alternatively spliced variant of CXCR3 mediates the IP-10, Mig, and I-TAC induced-inhibition of endothelial cell growth and acts as functional receptor for PF-4”. J Exp Med. 2003 Jun 2. (I.F. 14,484). F1000 rating of 4.8: “Must read. Paper of general interest containing a new finding and a novel interesting hypothesis”.
54. Rotondi M, Lazzeri E, Romagnani P, Serio M. “Role for interferon-g-inducible chemokines in endocrine autoimmunity: An expanding field”. Review. Journal of Endocrinological Investigation. 2002 Jun 25:177-180. (I.F. 1,476).
55. Lazzeri E, Lasagni L, Serio M, Romagnani S, Romagnani P. “Cytokines and chemokines in nephropathies and renal transplant”. G Ital Nefrol.2002 Nov-Dec;19(6):641 9.
56. Annunziato F, Cosmi L, Liotta F, Lazzeri E, Manetti R, Vanini V, Romagnani P, Maggi E, Romagnani S. “Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes.” J Exp Med. 2002 Aug 5;196(3):379-87. (I.F. 14,484). F1000 rating of 3: “Recommended. Paper of specialist interest containing a new finding”.
57. Romagnani P, Rotondi M, Lazzeri E, Lasagni L, Francalanci M, Buonamano A, Milani S, Vitti P, Chiovato L, Tonacchera M, Bellastella A and Serio M. “Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves’ disease”. American Journal of Pathology. Jul 2002; 161(1): 195-206. (I.F. 6.750)
58. Romagnani P, Lazzeri E, Lasagni L, Mavilia C, Beltrame C, Francalanci M, Rotondi M, Annunziato F, Maurenzig L, Cosmi L, Galli G, Salvadori M, Maggi E and Serio M. “IP-10 and Mig production by glomerular cells in human proliferative glomerulonephritis and their regulation by nitric oxide”. J Am Soc Nephrol. 2002 Jan; 13(1):53-64. (I.F. 7.505)
59. Piccinni MP, Scaletti C, Mavilia C, Lazzeri E, Romagnani P, Natali I, Pellegrini S, Livi C, Romagnani S, Maggi E. “Production of IL-4 and leukemia inhibitory factor by T cells of the cumulus oophorus: a favorable microenvironment for pre-implantation embryo development”. European Journal of Immunology. 2001 Aug;31(8):2431-7. (I.F. 4,832).
60. Annunziato F, Romagnani P, Cosmi L, Lazzeri E, Romagnani S. “Chemokines and lymphopoiesis in human thymus”. Trends in Immunology. 2001 May;22(5):277-81.Review. (I.F. 15,507).
61. Romagnani P, Annunziato F, Lazzeri E, Cosmi L, Beltrame C, Lasagni L, Galli G, Francalanci M, Manetti R, Marra F, Vanini V, Maggi E and Romagnani S. “Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR)ab⁺CD8⁺ single-positive T cells, TCRgd⁺ T cells, and natural killer-type cells in human thymus”. Blood 2001 Feb. 1;97(3):601-7. (I.F. 10.432).
62. Romagnani P, Annunziato F, Lasagni L, Lazzeri E, Beltrame C, Francalanci M, Uguccioni M, Galli G, Cosmi L, Maurenzig L, Maggiolini M, Maggi E, Romagnani S and Serio M. “Cell-cycle dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity”.Journal of Clinical Investigation. 2001 Jan;107(1):53-63. Paper selected for the cover of the journal. Paper selected for an editorial by John Ashkenas, Science Editor. (I.F. 14,051)
63. Annunziato F, Romagnani P, Cosmi L, Beltrame C, Steiner BH, Lazzeri E, Raport CJ, Galli G, Manetti R, Mavilia C, Vanini V, Chantry D, Maggi E, Romagnani S. “Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: possible implications for negative selection”.Journal of Immunology. 2000 Jul 1; 165(1):238-46. (I.F. 7,014)
64. Galli G, Chantry D, Annunziato F, Romagnani P, Cosmi L, Lazzeri E, Manetti R, Maggi E, Gray PW, Romagnani S. “Macrophage-derived chemokine production by activated human T cells in vitro and in vivo: preferential association with the production of type 2 cytokines.” European Journal of Immunology. 2000 Jan; 30(1):204-10. (I.F. 4,832).