Personale

Recapiti

Orario di ricevimento

Italiano

Curriculum

Pubblicazioni

Insegnamenti

English

Curriculum

Interest

Maria Beatrice PASSANI

Ruolo attuale:: Professore Associato
SSD:: BIOS-11/A - Farmacologia
Afferenza organizzativa:: Dipartimento di Scienze della Salute (DSS)

Recapiti

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	beatrice.passani(AT)unifi.it

Maria Beatrice PASSANI

Curriculum

Maria Beatrice Passani ha ricevuto la laurea in Scienze Biologiche nel 1983 frequentando come studente il Dipartimento di Farmacologia Preclinica e Clinica dell’Universita’ di Firenze. Nel 1986 ha ottenuto il Master in Psicobiologia presso l’Universita’ di California Irvine (USA), dove ha appreso e applicato tecniche elettrofisiologiche e di immunoistochimica per studiare la plasticita’ sinaptica quale meccanismo fisiologico che sottende all’apprendimento e memoria. Nel 1993 ha conseguito il PhD in Scienze Biologiche presso la Columbia University di New York (USA). Durante il dottorato ha studiato lo sviluppo del sistema nervoso della sanguisuga, individuando specifiche interazioni molecolari che permettono l’acquisizione da parte dei neuroni delle loro caratteristiche morfologiche adulte. Nel 1993 MB Passani é tornata in Italia, svolgendo attivitá di ricerca come assegnista presso il Dipartimento di Farmacologia Preclinica e Clinica dell’Universitá di Firenze, e nel 2005 e’ diventata Ricercatore Universitario prendendo servizio alla Facolta’ di Farmacia della stessa Universitá. Inizialmente ha studiato il ruolo del sistema serotonergico centrale quale modulatore dell’attivita’ neuronale dell’ippocampo di ratto coinvolta in processi mnemonici. I suoi interessi si sono poi focalizzati sul ruolo del sistema istaminergico centrale nella memoria, nei processi omeostatici, e nella neuroinfiammazione usando modelli murini. I suoi studi hanno contribuito a spiegare come farmaci istaminergici possano avere risvolti terapeutici nel trattamento di patologie neurologiche con compromissione dei processi cognitivi, hanno evidenziato il potenziale terapeutico di farmaci istaminergici per il trattamento di disordini alimentari. Recentemente si è occupata anche del coinvolgimento del recettore istaminergico H4 nella patogenesi di malattie neuroinfiammatorie, studiando i suoi effetti nella encefalomielite sperimentale autoimmune, un modello sperimentale della sclerosi multipla

CURRICULUM DEGLI STUDI

1983 Laurea in Scienze Biologiche con il massimo dei voti e la lode presso l'Universitá degli Studi di Firenze. Titolo della tesi: Modulazione della neurotrasmissione da parte di adenosina e suoi derivati. Relatore Prof. F. Moroni.

1986 Diploma di Master of Science in Biological Sciences, University of California, Irvine, CA (USA)

1989 Diploma di Master Phylosophy, Graduate School of Arts and Sciences, Columbia University, New York, NY (USA)

1993 Diploma di Doctor of Phylosophy (Ph.D.), Graduate School of Arts and Sciences, Columbia University, New York, NY (USA) Titolo della tesi: Developmental strategies in the establishment of central and peripheral projections by leech neurons. Il titolo "Doctor of Phylosophy" é stato dichiarato equipollente al titolo di dottore di ricerca dell'ordinamento universitario italiano in data 13 ottobre, 1993.

CURRICULUM PROFESSIONALE

1981-1983 Studentessa Interna, Dipartimento di Farmacologia Preclinica e Clinica, Universitá di Firenze.

1983-1986 Master degree student, Dipartimento di Psicobiologia, University of California, Irvine, CA (USA).

1983-1986 Teaching assistant al corso di Psychobiology Lectures and Psychobiology Laboratory, University of California Irvine, CA (USA).

1986 Research Associate, Dipartimento di Scienze Biologiche, Columbia University, New York, NY (USA).

1987 Ammessa a frequentare il corso Neurobiology of the leech, Woods Hole Laboratories, Woods Hole, MA (USA).

1986-1991 Graduate Student (dottorando), Dipartimento di Scienze Biologiche, Columbia University, New York, NY (USA).

1987 Teaching assistant al corso di Neurobiology, Dipartimento di Scienze Biologiche, Columbia University, New York, NY (USA).

1992-1995 Borsista, Dipartimento di Farmacologia Preclinica e Clinica, Universitá di Firenze.

1994-1997 Assistente dell' Associate Editor di Neuroscience Letters

1999-2004 Assegnista di Ricerca presso il Dipartimento di Farmacologia, Universitá di Firenze

2005 Ricercatore presso il Dipartimento di Farmacologia, Universitá di Firenze

INSEGNAMENTI:
2009 titolare del corso Farmacologia e Farmacoterapia I, per il corso di laurea in Farmacia

BORSE DI STUDIO E PREMI

1987 Premio "Charles A. Huebschman" usufruito per partecipare al corso Neurobiology of the leech presso Woods Hole Laboratories, MA (USA)

1992-1993 Borsa di studio del Comitato di Gestione e Ricerca sui Farmaci (GESCO) nell'ambito del progetto Invecchiamento cerebrale e della convenzione tra il suddetto consorzio ed il Dipartimento di Farmacologia Preclinica e Clinica, Universitá di Firenze.

1994-1995 Borsa di studio dell' Universitá di Firenze offerta dalla ACRAF, Angelini Francesco S.P.A. usufruita presso il Dipartimento di Farmacologia Preclinica e Clinica, Universitá di Firenze.

1995-1997 Contratto di consulenza nell’ambito del PNR per la Pharmacia SpA

SOCIETA' SCIENTIFICHE:
SOCIETÁ ITALIANA DI FARMACOLOGIA
EUROPEAN HISTAMINE RESEARCH SOCIETY
SOCIETY FOR NEUROSCIENCE
EUROPEAN BEHAVIOURAL PHARMACOLOGY SOCIETY

Maria Beatrice PASSANI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Costa, Alessia; Ducourneau, Eva; Curti, Lorenzo; Masi, Alessio; Mannaioni, Guido; Hardt, Lola; Biyong, Essi F; Potier, Mylène; Blandina, Patrizio; Trifilieff, Pierre; Provensi, Gustavo; Ferreira, Guillaume; Passani, M Beatrice (2024). Chemogenetic activation or inhibition of histaminergic neurons bidirectionally modulates recognition memory formation and retrieval in male and female mice. SCIENTIFIC REPORTS, vol. 14, pp. 0-0, ISSN:2045-2322 DOI

Costa, Alessia; Micheli, Laura; Sordi, Virginia; Ciampi, Clara; Lucci, Jacopo; Passani, Maria Beatrice; Provensi, Gustavo (2024). Preventing social defeat stress-induced behavioural and neurochemical alterations by repeated treatment with a mix of Centella asiatica, Echinacea purpurea and Zingiber officinale standardized extracts. FRONTIERS IN PHARMACOLOGY, vol. 15, pp. 1-15, ISSN:1663-9812 DOI

Passani M.B.; Provensi G.; Piomelli D. (2023). Editorial: The paracannabinoid system: endocannabinoid-like lipids and their functions. FRONTIERS IN ENDOCRINOLOGY, vol. 14, pp. 1-2, ISSN:1664-2392 DOI

Franceschini, Alessandra; Mazzamuto, Giacomo; Checcucci, Curzio; Chicchi, Lorenzo; Fanelli, Duccio; Costantini, Irene; Passani, Maria Beatrice; Silva, Bianca Ambrogina; Pavone, Francesco Saverio; Silvestri, Ludovico (2023). Brain-wide neuron quantification toolkit reveals strong sexual dimorphism in the evolution of fear memory. CELL REPORTS, vol. 42, pp. 0-0, ISSN:2211-1247 DOI Accesso ONLINE all'editore

Costa, A.; Provensi, G.; Leurs, R.; Blandina, P.; Passani, B. (2023). Histaminergic neuronal pathways underlie susceptibility and resilience to psychosocial stress. NEUROSCIENCE APPLIED, vol. 2, pp. 102441-102441, ISSN:2772-4085 DOI

Costa, Alessia; Provensi, Gustavo; Passani, Maria (2023). TUBEROMAMMILLARY NUCLEUS HISTAMINERGIC NEURONS UNDERLIE SUSCEPTIBILITY AND RESILIENCE TO PSYCHOSOCIAL STRESS. IBRO NEUROSCIENCE REPORTS, vol. 15, pp. s632-s632, ISSN:2667-2421 DOI

Carlotta De Filippo, Alessia Costa, Maria Vittoria Becagli, Mariela Mejia Monroy, Gustavo Provensi, Maria Beatrice Passani (2023). Gut microbiota and oleoylethanolamide in the regulation of intestinal homeostasis. FRONTIERS IN ENDOCRINOLOGY, vol. 14, pp. 01-09, ISSN:1664-2392 DOI

Gustavo Provensi; Maria Beatrice Passani; Patrizio Blandina (2022). Different Peas in the Same Pod: The Histaminergic Neuronal Heterogeneity. In: springer. The Functional Roles of Histamine Receptors, pp. 303-327 Spingr, ISBN:978-3-031-16996-0. DOI

Gustavo Provensi, Alessia Costa, Barbara Rani, Maria Vittoria Becagli, Fabio Vaiano, Maria Beatrice Passani, Damiano Tanini, Antonella Capperucci, Simone Carradori, Jacobus P Petzer, Anél Petzer, Daniela Vullo, Gabriele Costantino, Patrizio Blandina, Andrea Angeli, Claudiu T Supuran (2022). New β-arylchalcogeno amines with procognitive properties targeting Carbonic Anhydrases and Monoamine Oxidases. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 244, pp. 1-11, ISSN:0223-5234 DOI

Scheila Daiane Schmidt, Eduarda Godfried Nachtigall, Lucas Aschidamini Marcondes, André Zanluchi, Cristiane R G Furini, Maria Beatrice Passani, Claudiu T Supuran, Patrizio Blandina, Ivan Izquierdo, Gustavo Provensi, Jociane de Carvalho Myskiw (2022). Modulation of Carbonic Anhydrases Activity in the Hippocampus or Prefrontal Cortex Differentially Affects Social Recognition Memory in Rats. NEUROSCIENCE, vol. 497, pp. 0-0, ISSN:0306-4522 DOI

Gustavo Provensi; Alessia Costa; Barbara Rani; Patrizio Blandina; Maria Beatrice Passani (2022). A Duet Between Histamine and Oleoylethanolamide in the Control of Homeostatic and Cognitive Processes. In: Passani Yanai. The Functional Roles of Histamine Receptors, pp. 389-410 Springer, ISBN:978-3-031-16996-0. DOI

Alessia Costa, Barbara Rani, Thomaz F S Bastiaanssen, Francesco Bonfiglio, Eoin Gunnigle, Gustavo Provensi, Moira Rossitto, Marcus Boehme, Conall Strain, Clara S Martínez, Patrizio Blandina, John F Cryan, Sophie Layé, Renato Corradetti, Maria Beatrice Passani (2022). Diet Prevents Social Stress-Induced Maladaptive Neurobehavioural and Gut Microbiota Changes in a Histamine-Dependent Manner. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 1-21, ISSN:1661-6596 DOI

Elisabetta Baldi, Alessia Costa, Barbara Rani, Maria Beatrice Passani, Patrizio Blandina, Adele Romano, Gustavo Provensi (2021). Oxytocin and fear memory extinction:possible implications for the therapyof fear disorders?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 1-26, ISSN:1422-0067 DOI Accesso ONLINE all'editore

Barbara Rani, Andrea Santangelo, Adele Romano, Justyna Barbara Koczwara, Marzia Friuli, Gustavo Provensi, Patrizio Blandina, Maurizio Casarrubea, Silvana Gaetani, Maria Beatrice Passani, Alessia Costa (2021). Brain histamine and oleoylethanolamide restore behavioral deficits induced by chronic social defeat stress in mice. NEUROBIOLOGY OF STRESS, vol. 14, pp. 1-11, ISSN:2352-2895 DOI

Gustavo Provensi; Alessio Nocentini; Maria Beatrice Passani; Patrizio Blandina; Claudiu T Supuran (2021). Activation of carbonic anhydrase isoforms involved in modulation of emotional memory and cognitive disorders with histamine agonists, antagonists and derivatives. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 36, pp. 719-726, ISSN:1475-6374 DOI

Barbara Rani; Bruna Silva-marques; Rob Leurs; Maria Beatrice Passani; Patrizio Blandina; Gustavo Provensi (2021). Short‐ and long‐term social recognition memory are differentially modulated by neuronal histamine. BIOMOLECULES, vol. 11, pp. 1-20, ISSN:2218-273X DOI

Patrizio Blandina, Gustavo Provensi, Maria Beatrice Passani, Clemente Capasso, Claudiu T. Supuran (2020). Carbonic anhydrase modulation of emotional memory. Implications for the treatment of cognitive disorders. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 35, pp. 1206-1214, ISSN:1475-6374 DOI

Adriano Lama, Gustavo Provensi, Roberta Amoriello, Claudio Pirozzi, Barbara Rani, Maria Pina Mollica, Giuseppina Mattace Raso, Clara Ballerini, Rosaria Meli, Maria Beatrice Passani (2020). The anti-inflammatory and immune-modulatory effects of OEA limit DSS-induced colitis in mice. BIOMEDICINE & PHARMACOTHERAPY, vol. 129, pp. 1-8, ISSN:1950-6007 DOI

Scheila Daiane Schmidt, Alessia Costa, Barbara Rani, Eduarda Godfried Nachtigall, Maria Beatrice Passani, Fabrizio Carta, Alessio Nocentini, Jociane de Carvalho Myskiw, Cristiane Regina Guerino Furini, Claudiu T. Supuran, Ivan Izquierdo, Patrizio Blandina, Gustavo Provensi (2020). The role of carbonic anhydrases in extinction of contextual fear memory. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, pp. 1-9, ISSN:0027-8424 DOI

Gustavo Provensi, Alessia Costa, Ivan Izquierdo, Patrizio Blandina, Maria Beatrice Passani (2020). Brain histamine modulates recognition memory; possible implications in major cognitive disorders. BRITISH JOURNAL OF PHARMACOLOGY, vol. 177, pp. 539-556, ISSN:0007-1188 DOI

Gustavo Provensi, Maria Beatrice Passani, Alessia Costa, Ivan Izquierdo, Patrizio Blandina (2020). Neuronal histamine and the memory of emotionally salient events. BRITISH JOURNAL OF PHARMACOLOGY, vol. 177, pp. 557-569, ISSN:0007-1188 DOI Accesso ONLINE all'editore

Franceschini, A; Costa, A; Costantini, I; Rani, B; Mazzamuto, G; Di Giovanna, P; Blandina, P; Passani, MB; Pavone, FS; Silvestri, L (2019). WHOLE-BRAIN MAPPING OF NEURONAL ACTIVATION IN HISTAMINERGIC NEURONS DURING AVERSIVE MEMORY PHASES. In: 48th Annual Meeting of the European-Histamine-Research-Society (EHRS), SPRINGER BASEL AG, vol. 68, pp. 16-16.

Alessandra Misto, Gustavo Provensi, Valentina Vozella, Maria Beatrice Passani, Daniele Piomelli (2019). Mast Cell-Derived Histamine Regulates Liver Ketogenesis via Oleoylethanolamide Signaling. CELL METABOLISM, vol. 29, pp. 91-102, ISSN:1550-4131 DOI

Gustavo Provensi, Scheila Daiane Schmidt, Marcus Boehme, Thomaz F. S. Bastiaanssen, Barbara Rani, Alessia Costa, Kizkitza Busca, Fiona Fouhy, Conall Strain, Catherine Stanton, Patrizio Blandina, Ivan Izquierdo, John F. Cryan, Maria Beatrice Passani (2019). Preventing adolescent stress-induced cognitive and microbiome changes by diet. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 116, pp. 9644-9651, ISSN:0027-8424 DOI

Gustavo Provensi, Fabrizio Carta, Alessio Nocentini, Claudiu T. Supuran, Fiorella Casamenti, Maria Beatrice Passani, Silvia Fossati (2019). A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 4724-4741, ISSN:1422-0067 DOI

Provensi G.; Costa A.; Passani M.B. (2018). Histaminergic Modulation of Recognition Memory. In: Abdel Ennaceur, Maria Angelica de Souza Silva. Handbook of Behavioral Neuroscience, pp. 415-445 Elsevier B.V., ISBN:9780128120125. DOI

Alessia Costa, Claudia Cristiano, Tommaso Cassano, Cristina Anna Gallelli, Silvana Gaetani, Carla Ghelardini, Patrizio Blandina, Antonio Calignano, Maria Beatrice Passani, Gustavo Provensi (2018). Histamine-deficient mice do not respond to the antidepressant-like effects of oleoylethanolamide. NEUROPHARMACOLOGY, vol. 135, pp. 234-241, ISSN:0028-3908 DOI Accesso ONLINE all'editore

Provensi, G ; Schmidt, SD; Rani, B ; Costa, A ; Carta, F ; de Carvalho Myskiw, J.; Passani, MB ; Izquierdo, I ; Supuran, CT; Blandina P (2018). BRAIN CARBONIC ANHYDRASES INHIBITION IMPAIRS FEAR MEMORY EXTINCTION IN RATS. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, vol. 123, pp. 61-61, ISSN:1742-7835

Costa, A ; Provensi, G ; Rani, B; Calignano, A; Cristiano, C; Passani, MB ; Blandina, P (2018). HISTAMINERGIC NEUROTRANSMISSION AS A GATEWAY INTEGRATING PERIPHERAL SIGNALS TO COORDINATE BEHAVIORAL RESPONSES. INFLAMMATION RESEARCH, vol. 67, pp. 9-9, ISSN:1023-3830

Monica Di Paola, Elena Bonechi, Gustavo Provensi, Alessia Costa, Gerard Clarke, Clara Ballerini, Carlotta De Filippo , M. Beatrice Passani (2018). Oleoylethanolamide treatment affects gut microbiota composition and the expression of intestinal cytokines in Peyer’s Patches of mice. SCIENTIFIC REPORTS, vol. 8, pp. 1-12, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Passani, Maria Beatrice; Benetti, Fernando; Blandina, Patrizio; Furini, Cristiane R.G.; de Carvalho Myskiw, Jociane; Izquierdo, Ivan (2017). Histamine regulates memory consolidation. NEUROBIOLOGY OF LEARNING AND MEMORY, vol. 145, pp. 1-6, ISSN:1074-7427 DOI Accesso ONLINE all'editore

Lucas Canto de Souza, Gustavo Provensi, Daniela Vullo, Fabrizio Carta, Andrea Scozzafava, Alessia Costa, Scheila D. Schmidt; Maria Beatrice Passani, Claudiu T. Supuran, Patrizio Blandina (2017). Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus.. NEUROPHARMACOLOGY, vol. 118, pp. 148-156, ISSN:1873-7064 DOI Accesso ONLINE all'editore

Gustavo Provensi, Roberta Fabbri, Leonardo Munari, Alessia Costa, Elisabetta Baldi, Corrado Bucherelli, Patrizio Blandina, Maria Beatrice Passani (2017). Histaminergic Neurotransmission as a Gateway for the Cognitive Effect of Oleoylethanolamide in Contextual Fear Conditioning.. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, vol. 20, pp. 392-399, ISSN:1461-1457 DOI

Santangelo, Andrea; Passani, Maria Beatrice; Casarrubea, Maurizio (2017). Brain histamine and behavioral neuroscience. ONCOTARGET, vol. 8, pp. 16107-16108, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Provensi, G.; Conti, E.; Pavarini, L.; Costa, A.; De Filippo, C.; Passani, M. B. (2016). EFFECTS OF OLEOYLETHANOLAMIDE SUBCHRONIC TREATMENT ON FOOD INTAKE, BODY WEIGHT AND GUT MICROBIOTA COMPOSITION IN NORMAL AND HISTAMINE DEFICIENT MICE: A PRELIMINARY STUDY. INFLAMMATION RESEARCH, vol. 65, pp. S53-S53, ISSN:1023-3830 DOI

Santangelo, A; Provensi, G; Costa, A; Casarrubea, M; Faulisi, F; Crescimanno, G; Ricca, V; Blandina, P; Passani, Mb (2016). Brain histamine depletion enhances motor sequences complexity of mice tested in open field: new insights from temporal pattern analysis. EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 26, pp. S279-S279, ISSN:0924-977X DOI

Passani Maria Beatrice (2016). Symposium IBRO 2016 Emotional memory: neural basis in animals and humans. In: IBRO 9th World Congress, Rio de Janeiro (Br), 7-11 2015, IBRO, pp. 48-48.

Maria Beatrice Passani, Roberto Coccurello (2016). The Endocannabinoid-Like Derivative Oleoylethanolamide at the Gut–Brain Interface: A “Lipid Way” to Control Energy Intake and Body Weight. In: Maria Beatrice Passani, Roberto Coccurello. Cannabinoids in Health and Disease, pp. 143-168 Rosaria Meccariello, Rosanna Chianese, ISBN:978-953-51-2430-6. DOI

Andrea Santangelo, Gustavo Provensi, Alessia Costa, Patrizio Blandina, Valdo Ricca, Giuseppe Crescimanno, Maurizio Casarrubea, Maria Beatrice Passani (2016). Brain histamine depletion enhances the behavioural sequences complexity of mice tested in the open-field: Partial reversal effect of the dopamine D2/D3 antagonist sulpiride.. NEUROPHARMACOLOGY, vol. 113, pp. 533-542, ISSN:1873-7064 DOI Accesso ONLINE all'editore

Hayato Umehara, Roberta Fabbri, Gustavo Provensi, Maria Beatrice Passani (2016). The hypophagic factor oleoylethanolamide differentially increases c-fos expression in appetite regulating centres in the brain of wild type and histamine deficient mice. PHARMACOLOGICAL RESEARCH, vol. 113, pp. 100-107, ISSN:1043-6618 DOI Accesso ONLINE all'editore

patrizio blandina; Maria Beatrice Passani (2016). Histamine receptors, Preclinical and Clinical Aspects. the Netherlands: Humana Press, ISBN:978-3-319-40306-9 DOI

Costa, A.; Mannelli, L. D. C.; Ghelardini, C.; Blandina, P.; Passani, M. B.; Provensi, G. (2016). Lack of antidepressant-like effect of oleoylethanolamide in histamine-deficient mice parallels reduced hippocampal and cortical CREB phosphorylation. INFLAMMATION RESEARCH, vol. 65, pp. 21-21, ISSN:1023-3830

Gustavo Provensi, Alessia Costa, Maria Beatrice Passani, Patrizio Blandina (2016). Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive effects in the mouse. NEUROPHARMACOLOGY, vol. 109, pp. 139-147, ISSN:0028-3908 DOI Accesso ONLINE all'editore

Roberta Fabbri, Cristiane Regina Guerino Furini, Maria Beatrice Passani, Gustavo Provensi, Elisabetta Baldi, Corrado Bucherelli, Ivan Izquierdo, Jociane de Carvalho Myskiw, Patrizio Blandina (2016). Memory retrieval of inhibitory avoidance requires histamine H receptor activation in the hippocampus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 113, pp. E2714-E2720, ISSN:0027-8424 DOI Accesso ONLINE all'editore

Fabbri, R.; Furini, C. R. G.; Passani, M. B.; Provensi, G.; Baldi, E.; Bucherelli, C.; Izquierdo, I.; de Carvalho Myskiw, J.; Blandina, P. (2016). Brain histamine modulates inhibitory-avoidance memory recall by activating H1 receptors in hippocampal CA1. INFLAMMATION RESEARCH, vol. 65, pp. S18-S19, ISSN:1023-3830 DOI

Silvana Gaetani, Adele Romano, Gustavo Provensi, Valdo Ricca, Thomas Lutz, Maria Beatrice Passani (2016). Eating disorders: From bench to bedside and back. JOURNAL OF NEUROCHEMISTRY, vol. 139, pp. 691-699, ISSN:0022-3042 DOI Accesso ONLINE all'editore

Maria Beatrice Passani (2016). SYMPOSIA: S14. GUT-BRAIN CROSSTALK IN THE REGULATION OF FEEDING AND EATING DISORDERS. In: 10th FENS Forum of Neuroscience, Copenhagen, 2-6 July 2016, FENS, pp. 6-7.

Aldinucci, Alessandra; Bonechi, Elena; Manuelli, Cinzia; Nosi, Daniele; Masini, Emanuela; Passani, Maria Beatrice; Ballerini, Clara (2016). Histamine regulates actin cytoskeleton in human toll-like receptor 4-activated monocyte-derived dendritic cells tuning CD4+ T lymphocyte response. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 291, pp. 14803-14814, ISSN:0021-9258 DOI Accesso ONLINE all'editore

Provensi G.; Blandina P.; Passani M.B. (2016). Histamine and appetite. In: Patrizio Blandina, Maria Beatrice Passani. Receptors, pp. 341-360 Humana Press Inc., ISBN:978-3-319-40306-9. DOI

Provensi, G.; Munari, L.; Baldi, E.; Bucherelli, C.; Blandina, P.; Passani, M.B. (2015). Histamine in the basolateral amygdala contributes to oleoylethanolamide-induced precognitive effects. INFLAMMATION RESEARCH, vol. 64, pp. 19-20, ISSN:1023-3830

Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Nicoletta Galeotti, Tommaso Cassano, Fernando Benetti, Renato Corradetti, Patrizio Blandina (2015). Brain histamine is crucial for selective serotonin reuptake inhibitors behavioral and neurochemical effects. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, vol. 18, pp. 1-10, ISSN:1461-1457 DOI

Fernando Benetti, Cristiane Regina Guerino Furini, Jociane De Carvalho Myskiw, Gustavo Provensi, Maria Beatrice Passani, Elisabetta Baldi, Corrado Bucherelli, Leonardo Munari, Ivan Izquierdo, Patrizio Blandina (2015). Histamine in the basolateral amygdala promotes inhibitory avoidance learning independently of hippocampus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 112, pp. E2536-E2542, ISSN:0027-8424 DOI Accesso ONLINE all'editore

Provensi, G; Benetti, F; Guerino Furini, CR; de Carvalho Myskiw J; Passani, MB; Izquierdo, I; Blandina, P (2015). LACK OF cAMP RESPONSE ELEMENT-BINDING PROTEIN (CREB) ACTIVATION PARALLELS ALPHA-FLUOROMETHYLHISTIDINE (a-FMHis)-INDUCED IMPAIRMENT OF LONG-TERM MEMORY OF STEP-DOWN INHIBITORY AVOIDANCE (IA). INFLAMMATION RESEARCH, vol. 64, pp. 21-21, ISSN:1023-3830 DOI

Gustavo Provensi, Patrizio Blandina, Maria Beatrice Passani (2015). The histaminergic system as a target for the prevention of obesity and metabolic syndrome. NEUROPHARMACOLOGY, vol. 136, pp. 3-12, ISSN:0028-3908 DOI Accesso ONLINE all'editore

G. Provensi, L. Munari, E. Baldi, C. Bucherelli, P. Blandina, M.B. Passani (2015). HISTAMINE IN THE BASOLATERAL AMYGDALA CONTRIBUTES TO OLEOYLETHANOLAMIDE-INDUCED PROCOGNITIVE EFFECTS. INFLAMMATION RESEARCH, vol. 64, pp. 19-20, ISSN:1023-3830 DOI

Adele Romano, Bianca Tempesta, Gustavo Provensi, Maria Beatrice Passani, Silvana Gaetani (2015). Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: Different lipid signals?. FRONTIERS IN PHARMACOLOGY, vol. 6, pp. 0-0, ISSN:1663-9812 DOI Accesso ONLINE all'editore

Provensi, G.; Passani, M.B.; Blandina, P. (2014). ABT-239 and donepezil require the integrity of the central histaminergic system to exert their behavioral and neurochemical effects. INFLAMMATION RESEARCH, vol. 63, pp. 9-10, ISSN:1023-3830

Fabbri, R.; Umehara, H.; Romano, A.; Gaetani, S.; Provensi, G.; Blandina, P.; Passani, M.B. (2014). Role of central histaminergic system in the anorexiant effect of oleoylethanolamide: a neuroanatomical study. INFLAMMATION RESEARCH, vol. 63, pp. 31-31, ISSN:1023-3830

Gustavo Provensi, Roberto Coccurello, Hayato Umehara, Leonardo Munari, Giacomo Giacovazzo, Nicoletta Galeotti, Daniele Nosi, Silvana Gaetani, Adele Romano, Anna Moles, Patrizio Blandina, Maria Beatrice Passani (2014). Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 111, pp. 11527-11532, ISSN:0027-8424 DOI

Claudia Musilli; Gaetano De Siena; Maria Elena Manni; Andrea Logli; Elisa Landucci; Riccardo Zucchi; Alessandro Saba;Riccardo Donzelli; Maria Beatrice Passani; Gustavo Provensi; Laura Raimondi (2014). Histamine mediates behavioural and metabolic effects of 3-iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism. BRITISH JOURNAL OF PHARMACOLOGY, vol. 171, pp. 3476-3484, ISSN:0007-1188 DOI

Benetti, F.; Furini, C.R.; de Carvalho Myskiw, J.; Passani, M.B.; Izquierdo, I.; Blandina, P. (2014). Role of the histaminergic system in short-term and long-term memory of step-down inhibitory avoidance (IAA). INFLAMMATION RESEARCH, vol. 63, pp. 29-30, ISSN:1023-3830

Konttinen, Yrjö T.; Henrik, Husu; Xia, Han; Passani, M. Beatrice; Clara, Ballerini; Vasily, Stegaev; Tarvo, Sillat; Zygmunt, Mackiewicz (2013). Non-professional Histamine Producing Cells, Immune Responses and Autoimmunity. In: Yrjö T. Konttinen, Henrik Husu, Xia Han, Beatrice Passani M, Clara Ballerini, Vasily Stegaev, Tarvo Sillat, Zygmunt Mackiewicz. Histamine H4 Receptor: A Novel Drug Target in Immunoregulation and Inflammation, pp. 201-258, online: Holger Stark, ISBN:9788376560564. DOI

Benetti, Fernando; Baldi, Elisabetta; Bucherelli, Corrado; Blandina, Patrizio; Passani, Maria Beatrice (2013). Histaminergic ligands injected into the nucleus basalis magnocellularis differentially affect fear conditioning consolidation. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, vol. 16, pp. 575-582, ISSN:1461-1457 DOI

Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Patrizio Blandina (2013). Selective brain region activation by histamine H(3) receptor antagonist/inverse agonist ABT-239 enhances acetylcholine and histamine release and increases c-fos expression.. NEUROPHARMACOLOGY, vol. 70, pp. 131-140, ISSN:0028-3908 DOI

C Ballerini; A Aldinucci; I Luccarini; A Galante; C Manuelli; P Blandina; M Katebe; PL Chazot; E Masini; MB Passani (2013). Antagonism of histamine H4 receptors exacerbates clinical and pathological signs of experimental autoimmune encephalomyelitis.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 170, pp. 167-177, ISSN:0007-1188 DOI

A. Pini;G. Mannaioni;D. Pellegrini-Giampietro;M. B. Passani;R. Mastroianni;D. Bani;E. Masini (2012). The role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain and ischemic stroke.. CURRENT DRUG TARGETS, vol. 13, pp. 984-993, ISSN:1389-4501 Accesso ONLINE all'editore

Passani MB (2012). H4R AND NEUROINFLAMMATION: INSIGHTS FROM MOUSE EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS. INFLAMMATION RESEARCH, vol. 61, pp. S46-S46, ISSN:1023-3830

Provensi G.; Munari L.; Blandina P.; Galeotti N.; Passani M. B. (2012). INTERACTIONS BETWEEN NEURONAL HISTAMINE AND OLEOYLETHANOLAMIDE IN THE CONTROL OF FOOD INTAKE: A BEHAVIORAL AND IMMUNOHISTOCHEMICAL STUDY. BEHAVIOURAL PHARMACOLOGY, vol. 23, pp. 626-635, ISSN:0955-8810 DOI

Pini A; Bani D; Passani MB; Rosa AC; Masini E. (2012). Role of histamine H4R in bleomycin-induced pulmonary fibrosis. INFLAMMATION RESEARCH, pp. S48-S48, ISSN:1023-3830

P. Blandina; G. Provensi; L. Munari; M.G. Giovannini; T. Garrison; J.R. Koenig; M. Cowart; J. Brioni; M.B. Passani (2012). LACK OF EFFECTS BY ABT239, A HISTAMINE H-3 RECEPTOR ANTAGONIST, IN HISTAMINE-DEFICIENT ANIMALS. In: 41st Annual Meeting of the European-Histamine-Research-Society (EHRS)/Meeting of the Cost Action BM0806 on Recent Advances in Histamine Receptor H4R Research, Belfast, NORTH IRELAND, MAY 02-05, 2012, vol. 61, pp. S62-S62.

M.B. Passani; C. Ballerini (2012). Histamine and neuroinflammation: insights from murine experimental autoimmune encephalomyelitis.. FRONTIERS IN SYSTEMS NEUROSCIENCE, vol. 6, pp. 0-0, ISSN:1662-5137

Blandina P.; Provensi G.; Munari L.; Giovannini M. G.; Garrison T.; Koenig J. R.; Cowart M.; Brioni J.; Passani M. B. (2012). LACK OF EFFECTS BY ABT239, A HISTAMINE H-3 RECEPTOR ANTAGONIST, IN HISTAMINE-DEFICIENT ANIMALS. INFLAMMATION RESEARCH, pp. S62-S62, ISSN:1023-3830

G. Provensi; L. Munari; P. Blandina; N. Galeotti; M. B. Passani (2012). THE ANOREXIANT EFFECT OF OLEOYLETHANOLAMIDE IS MODULATED BY NEURONAL HISTAMINE. INFLAMMATION RESEARCH, vol. 61, pp. 62-62, ISSN:1023-3830

Patrizio Blandina, Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani (2012). Histamine neurons in the tuberomamillary nucleus: a whole center or distinct subpopulations?. FRONTIERS IN SYSTEMS NEUROSCIENCE, vol. 6, pp. 1-6, ISSN:1662-5137 DOI Accesso ONLINE all'editore

L. Munari; G. Provensi; M.B. Passani; N. Galeotti; T. Cassano; P. Blandina (2011). IS BRAIN HISTAMINE INVOLVED IN DEPRESSION?. INFLAMMATION RESEARCH, vol. 60, pp. 339-339, ISSN:1023-3830

Passani MB (2011). ROLE OF HISTAMINE IN COGNITION: REVIEW OF RESULTS FROM ANIMAL STUDIES. JOURNAL OF PSYCHOPHARMACOLOGY, vol. 25, pp. A7-A7, ISSN:0269-8811

M.B. Passani; P. Blandina (2011). Histamine receptors in the CNS as targets for therapeutic intervention. TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 32, pp. 242-249, ISSN:0165-6147 DOI Accesso ONLINE all'editore

Y. Yanovsky; S. Li; B.P. Klyuch; Q. Yao; P. Blandina; M.B. Passani; J.S. Lin; H Haas; O.A. Sergeeva (2011). L-Dopa activates histaminergic neurons. THE JOURNAL OF PHYSIOLOGY, vol. 589, pp. 1349-1366, ISSN:0022-3751 DOI Accesso ONLINE all'editore

MB Passani; P Blandina; F Torrealba (2011). H3 Receptor Miniseries: The histamine H3 receptor and eating behavior. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 336, pp. 24-29, ISSN:0022-3565 DOI

E. Tiligada; K. Kyriakidis; P.L. Chazot; M.B. Passani (2011). Histamine pharmacology and new CNS drug targets.. CNS NEUROSCIENCE & THERAPEUTICS, vol. 17, pp. 620-628, ISSN:1755-5930 DOI

L. Munari; N. Galeotti; H. Ohtsu; P. Blandina; M.B. Passani (2010). OLEOYLETHANOLAMIDE AND BRAIN HISTAMINE INTERACT TO REGULATE FEEDING BEHAVIOUR. INFLAMMATION RESEARCH, vol. 59, pp. S318-S318, ISSN:1023-3830

P. Giannoni; A.D. Medhurst; M.B. Passani; M.G. Giovannini; C. Ballini; L. Della Corte; P. Blandina (2010). Regional differential effects of the novel histamine H3 receptor antagonist GSK189254 on histamine release in the CNS of freely moving rats. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 332, pp. 164-172, ISSN:1521-0103 DOI Accesso ONLINE all'editore

L. Munari; M.B. Passani; N. Galeotti; P. Giannoni; H. Ohtsu; P. Blandina (2010). EFFECTS OF CITALOPRAM ON TAIL SUSPENSION TEST REQUIRE THE PRESENCE OF NEURONAL HISTAMINE. INFLAMMATION RESEARCH, vol. 59, pp. S318-S318, ISSN:1023-3830

Blandina, Patrizio; Munari, Leonardo; Giannoni, Patrizia; Mariottini, Chiara; Passani, Maria Beatrice (2010). Histamine neuronal system as a therapeutic target for the treatment of cognitive disorders. FUTURE NEUROLOGY, vol. 5, pp. 543-555, ISSN:1479-6708 DOI

P Blandina; L Munari; P Giannoni; C Mariottini; M B Passani (2010). Histamine neuronal system as therapeutic target for the treatment of cognitive disorders. FUTURE NEUROLOGY, vol. 5, pp. 543-555, ISSN:1479-6708

Passani MB (2010). Histaminergic system and the CNS.. In: 7th FENS Forum of European Neuroscience, Amsterdam, Netherlands., 3- July 2010, FENS, pp. 1-1. Accesso ONLINE all'editore

Passani MB (2009). Interaction between histamine and other neurotransmitters.. In: Satellite Event of the Society for Neuroscience Meeting: Emerging Concepts in Brain Histamine and H3 Receptor Antagonists, Chicago, USA., October 16th-20th, not available, pp. x-x.

Passani MB (2009). H3 receptor antagonists and cognitive functions: good girls or bad boys?. BEHAVIOURAL PHARMACOLOGY, vol. 20, pp. S7-S7, ISSN:0955-8810

L. Munari; M.B. Passani (2009). Brain histamine affects eating and drinking behaviour. In: V.R. Preedy, R Ross Watson, C.R. Martin. Handbook of behavior, food and nutrition, pp. 319-336, New york USA: -Attuale: SPRINGER, 233 SPRING STREET, NEW YORK, USA, NY, 10013 -Plenum Press:Book Customer Service, 233 Spring Street:New York, NY 10013:(212)620-8471, (212)620-8000, EMAIL: info@plenum.com, INTERNET: http://www.plenum.com, Fax: (212)807-1047. DOI

C.Mariottini;T.Scartabelli;G.Bongers;S.Arrigucci;D.Nosi;R.Leurs;A.Chiarugi; P.Blandina;DE.Pellegrini-Giampietro;M.B.Passani (2009). Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults.. JOURNAL OF NEUROCHEMISTRY, vol. 110, pp. 1469-1478, ISSN:0022-3042 Accesso ONLINE all'editore

P. Blandina; M.B. Passani; L. Munari; P. Giannoni (2009). Implications of histaminergic neurons heterogeneity in cognitive enhancement elicited by H3 antagonists. In: 22nd Congress of the European-College-of-Neuropsychopharmacology, Istanbul, TURKEY, SEP 12-16, 2009, vol. 19, pp. S204-S204.

P. Giannoni; M.B. Passani; D. Nosi; P.L. Chazot; F.C. Shenton; A.D. Medhurst; L. Munari; P. Blandina (2009). Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 29, pp. 2363-2374, ISSN:0953-816X DOI Accesso ONLINE all'editore

M.B Passani; P. Blandina; K.E. Browman; G.B. Fox (2008). Cognitive Functions,Attention-Deficit Hyperactivity Disorders, and Alzheimer’s Disease. In: Divya Vohora. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders, pp. 213-239, USA: CRC PRESS-TAYLOR & FRANCIS GROUP, 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA.

L.Giannini; S.Nistri; R.Mastroianni; L.Cinci; A.Vannacci; C.Mariottini; MB.Passani; PF.Mannaioni; D.Bani; E.Masini. (2008). Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs.. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 12, pp. 2382-2394, ISSN:1582-1838 DOI Accesso ONLINE all'editore

Giannini L;Mastroianni R;Mariottini C;Passani MB;Nistri S;Mannaioni PF;Masini E (2007). Activation of cannabinoid receptors reduces allergen-induced oxidative stress damage during asthma-like reaction in sensitised guinea-pigs.. INFLAMMATION RESEARCH, vol. 56 Suppl 1, pp. 11-12, ISSN:1023-3830, Birkhaeuser Verlag AG:Viaduktstrasse 42-44, CH 4051 Basel Switzerland:011 41 61 2050707, EMAIL: subscriptions@birkhauser.ch, INTERNET: http://www.birkhauser.ch, Fax: 011 41 61 2050792: DOI

G. BONGERS; T. SALLMEN; MB. PASSANI; C. MARIOTTINI; D. WENDELIN; A. LOZADA; A. VAN MARLE; M. NAVIS; P. BLANDINA; R. A. BAKKER; P. PANULA; R LEURS (2007). The Akt/GSK-3b axis as a new signaling pathway of the histamine H3 receptor. JOURNAL OF NEUROCHEMISTRY, vol. 103, pp. 248-258, ISSN:0022-3042, Editore attuale:BLACKWELL PUBLISHING LTD, 9600 GARSINGTON RD, OXFORD, ENGLAND, OXON, OX4 2DG Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320: Accesso ONLINE all'editore

M. PASSANI; P. GIANNONI; C. BUCHERELLI; E. BALDI; P. BLANDINA (2007). HISTAMINE IN THE BRAIN: BEYOND SLEEP AND MEMORY. BIOCHEMICAL PHARMACOLOGY, vol. 73, pp. 1113-1122, ISSN:0006-2952

P. Blandina; M.B. Passani (2006). Central histaminergic system interactions and cognition. In: E.D. Levin. Neurotransmitter interactions and cognitive functions, pp. 149-163, Berlin (Germany): Birkhåuser Verlag.

C. BUCHERELLI; E. BALDI; C. MARIOTTINI; M.B. PASSANI; P. BLANDINA (2006). Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation. LEARNING & MEMORY, vol. 13, pp. 426-430, ISSN:1549-5485 DOI Accesso ONLINE all'editore

G. Cenni; M.B. Passani; P.F. Mannaioni; P Blandina (2006). Betahistine increases ACh release from the cortex, but not histamine release from the nucleus basalis magnocellularis of freely-moving rats. INFLAMMATION RESEARCH, vol. 55, pp. S28-S29, ISSN:1023-3830

C. Bucherelli; E. Baldi; C. Mariottini; M.B. Passani; P. Blandina (2006). Aversive memory consolidation and reconsolidation: differences in neuro-transmitter engagement. In: XXXVth Annual Meeting of European Histamine Research Society, Delphi, Greece, 10-13/05/2006, Medical school of the University of Athens, pp. 38-38.

G.Cenni; P.Blandina; K.Mackie; D.Nosi; L.Formigli; P.Giannoni; C.Ballini; L.Della Corte; P.F.Mannaioni; M.B.Passani (2006). Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 24, pp. 1633-1644, ISSN:0953-816X

E. BALDI; C. BUCHERELLI; W. SCHUNACK; G. CENNI; P. BLANDINA; M.B. PASSANI (2005). The H3 receptor protean agonist proxyfan enhances the expression of fear memory in the rat. NEUROPHARMACOLOGY, vol. 48, pp. 1-6, ISSN:0028-3908

VANNACCI A.; GIANNINI L.; ZAGLI G.; PIERPAOLI S; MARZOCCA C; PASSANI M.B.; MASINI E.; MANNAIONI P.F. (2004). 2-arachidonyl glycerol inhibits the immunological activation of human basophils and of guinea pig mast cells. Modulation by nitric oxide.. In: Bienenstock J., Ring J., Togias A.G.. Allergy Frontiers and Future, pp. ---, cambridge: Hogrefe and Huber press.

M.B. Passani; J. Cangioli; P. Blandina (2004). The influence of histamine on memory. In: A. Falus, N. Grosman, Z.S.Darvas. Histamine: Biology and Medical Aspects, pp. 290-299, Basel (CH): Karger.

G. Cenni; J. Cangioli; A. Yamatodani; M.B. Passani; P.F. Mannaioni; A.M. Di Felice; P. Blandina (2004). Thioperamide-elicited increase of histamine release from basolateral amygdala of freely moving rats and its therapeutic implications. INFLAMMATION RESEARCH, pp. S53-S54, ISSN:1023-3830

Vannacci A; Giannini L; Passani MB; Di Felice A; Pierpaoli S; Zagli G; Fantappie' O; Mazzanti R; Masini E; Mannaioni PF (2004). The endocannabinoid 2-arachidonylglycerol decreases the immunological activation of Guinea pig mast cells: involvement of nitric oxide and eicosanoids.. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 311, pp. 256-264, ISSN:0022-3565 DOI

M.B. PASSANI; P. BLANDINA (2004). The neuronal histaminergic system in cognition. CURRENT MEDICINAL CHEMISTRY. CENTRAL NERVOUS SYSTEM AGENTS, vol. 4, pp. 17-26, ISSN:1568-0150

M.B. PASSANI; J.-S. LIN; A. HANCOCK; S. CROCHET; P. BLANDINA (2004). The histamine H3 receptor as a novel therapeutic target for cognitive and sleep disorders. TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 25, pp. 618-625, ISSN:0165-6147, Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010: Accesso ONLINE all'editore

P. Blandina; M. Efoudebe; G. Cenni; P.F. Mannaioni; M.B. Passani (2004). Acetylcholine, histamine and cognition: two sides of the same coin. LEARNING & MEMORY, vol. 11, pp. 1-8, ISSN:1072-0502

M.G. Giovannini; M. Efoudebe; M.B. Passani; E. Baldi; C. Bucherelli; F. Giachi; R. Corradetti; P. Blandina (2003). Improvement in fear memory by histamine-elicited ERK2 activation in hippocampal CA3 cells. THE JOURNAL OF NEUROSCIENCE, vol. 23, pp. 9016-9023, ISSN:0270-6474

Vannacci A;Baronti R;Zagli G;Marzocca C;Pierpaoli S;Bani D;Passani MB;Mannaioni PF;Masini E (2003). Carbon monoxide modulates the response of human basophils to FcepsilonRI stimulation through the heme oxygenase pathway.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 465, pp. 289-297, ISSN:0014-2999, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

A. Vannacci; M. B. Passani; S. Pierpaoli; L. Giannini; P. F. Mannaioni; E. Masini (2003). Nitric oxide modulates the inhibitory effect of cannabinoids on the immunological activation of guinea pig mast cells.. INFLAMMATION RESEARCH, vol. 52 Suppl 1, pp. S07-S08, ISSN:1023-3830

VANNACCI A; BARONTI R; ZAGLI G; MARZOCCA C; PIERPAOLI S; D. BANI; PASSANI MB; MANNAIONI PF; MASINI E. (2003). Carbon monoxide modulates the response of human basophils to FcεRI stimulation through the heme oxygenase pathway.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 465, pp. 289-297, ISSN:0014-2999

Passani MB (2002). Cannabinoids modulate the activation of human and guinea pig immunocytes.. In: II International Symposium on Molecular Medicine, Vadodara (India), 20-13 Jan 2002, pp. x-x.

I. Cangioli; M.B. Passani; E. Baldi; P.F. Mannaioni; C. Bucherelli; P. Blandina (2002). Activation of histaminergic H3 receptors in the rat basolateral amygdala enhances acetylcholine release and improves expression of fear memory. In: XXXIst Meeting of the European Histamine research Society, Eger, Hungary, 22-26/05/2002, pp. 50-50.

M.G. GIOVANNINI; C. BUCHERELLI; E. BALDI; M.B. PASSANI; I. CANGIOLI; M.D. EFOUDEBE; P.BLANDINA. (2002). Activation of hippocampal istamine H2 or H3 receptors improbes emotional memory and elicits phosphorylation of ERKS in rat hippocampal slices.. In: 32nd Annual Meeting of the Society for Neuroscience, pp. Program No. 379.18-Program No. 379.18.

A. Vannacci; G. Zagli; C. Marzocca; S. Pierpaoli; M. B. Passani; P. F. Mannaioni; E. Masini (2002). Down-regulation by cannabinoids of the immunological activation of human basophils and guinea pig mast cells.. INFLAMMATION RESEARCH, vol. 51 Suppl 1, pp. S09-S10, ISSN:1023-3830

Passani MB; Baldi E; Cangioli I; Efoudebe M; Giovannini MG; Bucherelli C; Blandina P (2002). Theraeutic potentials of histaminergic compounds.. In: COST Action D13 Workshop: New molecules towards human health care, Firenze (Italy), 17-20 April 2002, pp. 25-25.

M.B. Passani; I. Cangioli; E. Baldi; C. Bucherelli; P. Blandina (2002). Hystamine H3 receptor agonists increase acetylcholine release from rat basolateral amygdala in vivo, and ameliorate emtional memory. In: SFN 32nd Annual Meeting, Orlando, Florida, 2-7/11/2002, pp. 682.12-682.12.

I. Cangioli; E. Baldi; P.F. Mannaioni; C. Bucherelli; P. Blandina; M.B. Passani (2002). Activation of histaminergic H3 receptors in the rat basolateral amygdala improves expression of fear memory and enhances acetylcholine release. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 16, pp. 521-528, ISSN:0953-816X

L. BACCIOTTINI; M.B. PASSANI; L. GIOVANNELLI; I. CANGIOLI; P.F. MANNAIONI; W. SCHUNACK; P. BLANDINA (2002). Endogenous histamine in the medial septum-diagonal band comp-lex increases the release of acetylcholine from the hippocampus: a dual probe microdialysis study in the freely moving rat. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 15, pp. 1669-1680, ISSN:0953-816X

L. BACCIOTTINI; M.B. PASSANI; P.F. MANNAIONI; P. BLANDINA (2001). Interactions between histaminergic and cholinergic systems in learning and memory. BEHAVIOURAL BRAIN RESEARCH, vol. 124, pp. 183-194, ISSN:0166-4328

M.B.Passani; I. Cangioli; E. Baldi; C. Bucherelli; P.F. Mannaioni; P. Blandina (2001). Histamine H3 receptor-mediated impairment of contextual fear conditioning, and in-vivo inhibition of cholinergic transmission in the rat basolateral amygdala. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 14, pp. 1522-1532, ISSN:0953-816X

M. CECCHI; M.B. PASSANI; L. BACCIOTTINI; P.F. MANNAIONI; P. BLANDINA (2001). Cortical acetylcholine release elicited by stimulation of histamine H1 receptors in the nucleus basalis magnocellularis: a dual-probe microdialysis study in the freely moving rat.. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 13, pp. 68-78, ISSN:0953-816X

M.B. Passani; I. Cangioli; E. Baldi; P.F. Mannaioni; C. Bucherelli; P. Blandina (2001). Histaminergic modulation of cholinergic neurotransmission in the amygdala and of contextual fear conditioning. In: XXX Annual Meeting of European Histamine Research Society, Turku/Abo, Finland, 9-12/05/2001, pp. 26-26.

I. Cangioli; M.B. Passani; C. Bucherelli; E. Baldi; P.F. Mannaioni; P. Blandina (2001). Histaminergic modulation of contextual fear conditioning. In: XXX National Congress of the Italian Pharmacological Society, Genova, Italia, 30/05-02/06/2001, vol. 43 (Suppl. A), pp. 78-78.

M.B. Passani; L. Bacciottini; J. Cangioli; L. Giovannelli; P.F. Mannaioni; P. Blandina (2001). Histaminergic modulation of basal forebrain cholinergic neurons. In: T. Watanabe, H. Timmerman, K. Yanai. Histamine Research in the New Millenium, pp. 45-50, Amsterdam (NL): Elsevier Science B.V..

L. Bacciottini; L. Giovannelli; M.B. Passani; W. Schunack; P.F. Mannaioni; P. Blandina (2000). Ciproxifan and cimetidine modulate c-fos expression in septal neurons, and acetylcholine release from hippocampus of freely moving rats. INFLAMMATION RESEARCH, vol. 49, pp. S41-S42, ISSN:1023-3830

M.B. PASSANI; L. BACCIOTTINI; P.F.MANNAIONI; P. BLANDINA (2000). Central histaminergic system and cognition. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, vol. 24, pp. 107-114, ISSN:0149-7634

M.B. Passani; I. Cangioli; L. Bacciottini; P.F. Mannaioni; P.Blandina (2000). Thioperamide and cimetidine modulate acetylcholine release from the amygdala of freely moving rats. INFLAMMATION RESEARCH, vol. 49, pp. S43-S44, ISSN:1023-3830

A. ARCANGELI; B. ROSATI; O. CROCIANI; A. CHERUBINI; L. FONTANA; B. PASSANI; E. WANKE; M. OLIVOTTO (1999). Modulation of HERG current and herg gene expression during retinoic acid treatment of human neuroblastoma cells: potentiating effects of BDNF.. JOURNAL OF NEUROBIOLOGY, vol. 40, pp. 214-225, ISSN:0022-3034 Accesso ONLINE all'editore

A.M. PUGLIESE; MB. PASSANI; R. CORRADETTI (1998). Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 124, pp. 93-100, ISSN:0007-1188 Accesso ONLINE all'editore

A. ARCANGELI; B. ROSATI; A. CHERUBINI; O. CROCIANI; L. FONTANA; B. PASSANI; E. WANKE; M. OLIVOTTO (1998). Long term exposure to retinoic acid induces the expression of IRK1 channels in HERG channel-endowed neuroblastoma cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 244, pp. 706-711, ISSN:0006-291X Accesso ONLINE all'editore

M.B. Passani; P. Blandina (1998). Cognitive implications for H3 and 5-HT3 receptor modulation of cortical cholinergic function: a parallel story. METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, vol. 20, pp. 725-733, ISSN:0379-0355

PUGLIESE A.M.; PASSANI M.B.; CORRADETTI R. (1998). The inhibition of excitatory synaptic potentials by serotonin in the CA1 hippocampal slices is mediated by 5-HT1A receptors. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 10(10), pp. 394-394, ISSN:0953-816X

M. B. Passani; C. Luceri; G. Caderni; P. Dolara (1998). Intercellular communication in normal and aberrant crypts of rat colon mucosa. CANCER LETTERS, vol. 123, pp. 77-81, ISSN:0304-3835, Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114:

PUGLIESE A.M.; PASSANI M.B.; CORRADETTI R (1997). The selective 5-HT1A antagonist WAY 100635 blocks the serotonin-evoked decrease in EPSP in the CA1 region of rat hippocampal slices. In: Society for Neuroscience, 26th Annual Meeting, New Orleans, Lousiana, USA, 25-30 Ottobre 1997, aa, pp. 974-974.

MB. PASSANI; R. CORRADETTI (1996). Therapeutic potentials of DAU 6215 (Itasetron), a novel 5-HT3 receptor antagonist, in the treatment of central nervous disorders.. CNS DRUG REVIEWS, vol. 2, pp. 195-213, ISSN:1080-563X

PUGLIESE A.M.; PASSANI M.B.; PEPEU G.; CORRADETTI R. (1996). Felbamate blocks the N-methyl-D-aspartate-mediated component of excitatory synaptic potentials and synaptically driven cell firing of CA1 hippocampal pyramidal cells. FUNDAMENTAL & CLINICAL PHARMACOLOGY, vol. 10(2), pp. 211-211, ISSN:0767-3981

A.M. PUGLIESE; MB. PASSANI; G. PEPEU; R. CORRADETTI (1996). Felbamate decreases synaptic potentials and CA1 pyramidal cells in rat hippocampal slices.. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 279, pp. 1100-1108, ISSN:0022-3565 Accesso ONLINE all'editore

L.R. Wolszon; M.B. Passani; E.R. Macagno (1995). Interactions during a critical period inhibit bilateral projections in embryonic neurons.. THE JOURNAL OF NEUROSCIENCE, vol. 15, pp. 1506-1515, ISSN:0270-6474

L.R.Wolszon; WQ.Gao; M.B.Passani;E.R.Macagno (1994). Growth cone "collapse" in vivo: are inhibitory interactions mediated by gap Junctions?. THE JOURNAL OF NEUROSCIENCE, vol. 14, pp. 999-1010, ISSN:0270-6474

MB. PASSANI; A.M. PUGLIESE; M. AZZURRINI; R. CORRADETTI (1994). Effects of DAU 6215, a novel 5-hydroxytryptamine3 (5-HT3) antagonist on electrophysiological properties of the rat hippocampus.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 112(2), pp. 695-703, ISSN:0007-1188 Accesso ONLINE all'editore

A.M. PUGLIESE; L. BALLERINI; MB. PASSANI; R. CORRADETTI (1994). EPSP-spike potentiation during primed burst-induced long-term potentiation in the CA1 region of rat hippocampal slices. NEUROSCIENCE, vol. 62, pp. 1021-1032, ISSN:0306-4522

M.B.Passani; A.Peinado; H.Engelman; C.A.Baptista; E.R.Macagno (1991). Normally unused positional cues guide ectopic afferents in the leech CNS. THE JOURNAL OF NEUROSCIENCE, vol. 11, pp. 3868-3876, ISSN:0270-6474

Consi TR;Passani MB;Macagno ER (1990). Eye movements in Daphnia magna. Regions of the eye are specialized for different behaviors.. JOURNAL OF COMPARATIVE PHYSIOLOGY. A, NEUROETHOLOGY, SENSORY, NEURAL, AND BEHAVIORAL PHYSIOLOGY, vol. 166, pp. 411-420, ISSN:0340-7594

E.R.Macagno; W-Q.Gao; C.A.Baptista; M.B.Passani (1990). Competition or inhibition? Developmental strategies in the establishment of peripheral projections by leech neurons.. JOURNAL OF NEUROBIOLOGY, vol. 2, pp. 107-119, ISSN:0022-3034

R. CORRADETTI; G. LO CONTE; F. MORONI; MB. PASSANI; G. PEPEU (1984). Adenosine decreases aspartate and glutamate release from rat hippocampal slices.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 104, pp. 19-26, ISSN:0014-2999, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

R. CORRADETTI; F. MORONI; MB. PASSANI; G. PEPEU (1984). 8-phenyltheophylline potentiates the evoked electrical activity in hippocampal slices.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 103, pp. 177-180, ISSN:0014-2999, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

Maria Beatrice PASSANI

Curriculum

Maria Beatrice Passani received the Degree in Biological Sciences the Universitá di Firenze, Italy in 1983. She then obtained a Master Degree in 1986 at the Dept of Psychobiology, University of Irvine, California (CA,USA). During this period she learned electrophysiological and immunohistochemical techniques to study hippocampal synaptic plasticity as a physiological mechanism subserving learning and memory storage. She then received the Doctoral Degree in Biological Science in 1993 at Columbia University in New York (NY, USA). Her studies focused on the developmental strategies of the leech nervous system contributing to delineate specific molecular interactions during the development of leech neurons, which serve to define their adult morphology and synaptic connections. MB Passani returned to Firenze (I) and worked as a Research Fellow at the Dept. of Preclinical and Clinical Pharmacology. She was appointed Assistant Professor in Pharmacology at the School of Pharmacy of the Universitá di Firenze in 2005. Initially she studied the role of serotonergic modulation of excitatory neurotransmission in the rat hippocampus as correlates of cognitive processes. Recently she became interested in the physiological role of histamine as a central neurotransmitter involved in cognitive and homeostatic processes and brain inflammation. Her studies contributed to the understanding of if and how brain histamine may have a prospective role in the therapy of neurological and psychiatric disorders using murine models. She is currently engaged in a project aimed at understanding the relevance of brain histamine in controlling feeding behavior and evaluating the potential therapeutic use of histaminergic ligands for the treatment of eating disorders. She is also involved in learning the role of the histamine H4 receptor in the pathogenesis of neuroinflammatory autoimmune diseases, in particular in experimental autoimmune encephalomyelitis (EAE) a murine model of multiple sclerosis
Education:

Professional Curriculum

1983-1986 Master degree student, Dept of Psychobiology, University of California, Irvine (CA)
1983-1986 Teaching assistant for Psychobiology Lectures and Psychobiology Laboratory, University of California Irvine, (CA).
1986 Research Associate, Dept of Biological Sciences, Columbia University, New York (NY).
1987 Attended the course Neurobiology of the leech, Woods Hole Laboratories, Woods Hole (MA)
1986-1991 Graduate Student at Dept of Biological Sciences, Columbia University, New York (NY)
1987 Teaching assistant of the course in Neurobiology, Dept of Biological Sciences, Columbia University, New York (NY).
1992-2004 Research Fellow at the Dept of Preclinical e Clinical Pharmacology, Universitá di Firenze (I).
1994-1997 Assistant to the associate Editor of Neuroscience Letters
2005 Assistant Professor at the Dept of Preclinical e Clinical Pharmacology, Universitá di Firenze (I).

Teaching Assignments:
Undergraduate course: Pharmacology and Pharmacotherapy

Graduate courses Hospital pharmacology
Neurobiology of drug addiction

Member of:
SOCIETÁ ITALIANA DI FARMACOLOGIA
EUROPEAN HISTAMINE RESEARCH SOCIETY
SOCIETY FOR NEUROSCIENCE

EUROPEAN BEHAVIOURAL PHARMACOLOGY SOCIETY