Personale

Recapiti

Italiano

Pubblicazioni

Insegnamenti

Laura MICHELI

Ruolo attuale:: Ricercatore Legge 240/10 a tempo determinato
SSD:: BIOS-11/A - Farmacologia
Afferenza organizzativa:: Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)

Recapiti

laura.micheli(AT)unifi.it

Avvisi

Corso ADE "Dolore cronico: dai meccanismi fisiopatologici alle nuove prospettive terapeutiche"

L. Micheli – E. Lucarini Il corso si terrà il 25 luglio (Dip. Neurofarba, aula A, Cubo 2, 1 Piano) 9:30 – 18:30. Per le iscrizioni inviare una mail a laura.micheli@unifi.it o a elena.lucarini@unifi.it entro il 18/07/2025.

Laura MICHELI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Micheli, Laura; Balayssac, David; Busserolles, Jérôme; Dalbos, Cristelle; Prival, Laetitia; Richard, Damien; Quintana, Mercedes; Di Cesare Mannelli, Lorenzo; Toti, Alessandra; Ciampi, Clara; Ghelardini, Carla; Vlasakova, Katerina; Glaab, Warren E.; Hu, Yang; Loryan, Irena; Perrault, Olivier; Slaoui, Mohamed; Wuersch, Kuno; Johnson, Eric; Frieauff, Wilfried; Penraat, Kelley; Brees, Dominique; Dubost, Valérie; Theil, Diethilde (2025). The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project). TOXICOLOGY, vol. 510, pp. 0-0, ISSN:0300-483X DOI

Fiani, Silvia; Maestrelli, Francesca; Micheli, Laura; Cirri, Marzia; Mennini, Natascia; Mura, Paola (2025). Curcumin’s niosomes coated with chitosan for the treatment of osteoarthritis: effect of cyclodextrin complexation. INTERNATIONAL JOURNAL OF PHARMACEUTICS, pp. 0-0, ISSN:0378-5173 DOI

Arias, Hugo R.; Micheli, Laura; Jensen, Anders A.; Galant, Sonya; Vandermoere, Franck; Venturi, Daniel; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Marin, Philippe; Di Cesare Mannelli, Lorenzo (2025). Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors. BIOMÉDECINE & PHARMACOTHÉRAPIE, vol. 184, pp. 1-15, ISSN:0753-3322 DOI

Micheli Laura, Vasarri Marzia, Degl'Innocenti Donatella , Di Cesare Mannelli Lorenzo, Ghelardini Carla , Emiliano Antiga, Verdelli Alice , Caproni Marzia, Barletta Emanuela (2024). Posidonia oceanica (L.) Delile Is a Promising Marine Source Able to Alleviate Imiquimod-Induced Psoriatic Skin Inflammation. MARINE DRUGS, vol. 22, pp. 0-0, ISSN:1660-3397 DOI Accesso ONLINE all'editore

Micheli, Laura; Nobili, Stefania; Lucarini, Elena; Toti, Alessandra; Margiotta, Francesco; Ciampi, Clara; Venturi, Daniel; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2024). New insights in the mechanisms of opioid analgesia and tolerance: Ultramicronized palmitoylethanolamide down-modulates vascular endothelial growth factor-A in the nervous system. PHARMACOLOGICAL RESEARCH, vol. 209, pp. 0-0, ISSN:1043-6618 DOI

Nobili, Stefania; Micheli, Laura; Lucarini, Elena; Toti, Alessandra; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo (2024). Ultramicronized N-palmitoylethanolamine associated with analgesics: Effects against persistent pain. PHARMACOLOGY & THERAPEUTICS, vol. 258, pp. 0-0, ISSN:0163-7258 DOI

Micheli, Laura; Toti, Alessandra; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Crocetti, Letizia; Farina, Carlo; Scherz, Michael (2024). Synthesis and Anti‐Hyperalgesic Efficacy of MP‐103, a Non‐Racemic Enantiomeric Mixture of a New 1,4‐Diazabicyclo[4.3.0]nonan‐9‐one. CHEMISTRYSELECT, vol. 9, pp. 0-0, ISSN:2365-6549 DOI

Costa, Alessia; Micheli, Laura; Sordi, Virginia; Ciampi, Clara; Lucci, Jacopo; Passani, Maria Beatrice; Provensi, Gustavo (2024). Preventing social defeat stress-induced behavioural and neurochemical alterations by repeated treatment with a mix of Centella asiatica, Echinacea purpurea and Zingiber officinale standardized extracts. FRONTIERS IN PHARMACOLOGY, vol. 15, pp. 1-15, ISSN:1663-9812 DOI

Hugo R. Arias, Laura Micheli, Deborah Rudin, Ophelie Bento, Saskia Borsdorf, Clara Campi, Philippe Marin, Evgeni Ponimaskin, Dina Manetti, Maria Novella Romanelli, Carla Ghelardini, Matthias E. Liechti, Lorenzo Di Cesare Mannelli (2024). Non-hallucinogenic compounds derived from iboga alkaloids alleviate neruopathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation. BIOMEDICINE & PHARMACOTHERAPY, vol. 177, pp. 1-14, ISSN:1950-6007 DOI

Micheli, Laura; Muraglia, Marilena; Corbo, Filomena; Venturi, Daniel; Clodoveo, Maria Lisa; Tardugno, Roberta; Santoro, Valentina; Piccinelli, Anna Lisa; Di Cesare Mannelli, Lorenzo; Nobili, Stefania; Ghelardini, Carla (2024). The Unripe Carob Extract (Ceratonia siliqua L.) as a Potential Therapeutic Strategy to Fight Oxaliplatin-Induced Neuropathy. NUTRIENTS, vol. 17, pp. 0-0, ISSN:2072-6643 DOI

Lucarini E.; Micheli L.; Toti A.; Ciampi C.; Margiotta F.; Di Cesare Mannelli L.; Ghelardini C. (2023). Anti-Hyperalgesic Efficacy of Acetyl L-Carnitine (ALCAR) Against Visceral Pain Induced by Colitis: Involvement of Glia in the Enteric and Central Nervous System. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 0-0, ISSN:1422-0067 DOI

Micheli L.; Rajamoni J.; Di Cesare Mannelli L.; Rajagopalan P.; Ghelardini C.; Rajagopalan R. (2023). DDD-028: A potent, neuroprotective, non-opioid compound for the treatment of diabetic neuropathy. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 95, pp. 0-0, ISSN:1464-3405 DOI

Angeli A.; Micheli L.; Turnaturi R.; Pasquinucci L.; Parenti C.; Alterio V.; Di Fiore A.; De Simone G.; Monti S.M.; Carta F.; Di Cesare Mannelli L.; Ghelardini C.; Supuran C.T. (2023). Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 260, pp. 0-0, ISSN:0223-5234 DOI

Balayssac D.; Busserolles J.; Broto C.; Dalbos C.; Prival L.; Lamoine S.; Richard D.; Quintana M.; Herbet A.; Hilairet S.; Hu Y.; Loryan I.; Glaab W.E.; Micheli L.; Ghelardini C.; Di Cesare Mannelli L.; Perrault O.; Slaoui M. (2023). Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studies with oxaliplatin and paclitaxel - NeuroDeRisk project. BIOMEDICINE & PHARMACOTHERAPY, vol. 167, pp. 0-0, ISSN:1950-6007 DOI

Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Mosti, Carla Ghelardini, Anna Rita Bilia, Maria Camilla Bergonzi (2023). Antinociceptive Action of Thymoquinone-Loaded Liposomes in an In Vivo Model of Tendinopathy. PHARMACEUTICS, pp. 0-0, ISSN:1999-4923

Vanti, Giulia; Micheli, Laura; Berrino, Emanuela; Mannelli, Lorenzo Di Cesare; Bogani, Irene; Carta, Fabrizio; Bergonzi, Maria Camilla; Supuran, Claudiu T; Ghelardini, Carla; Bilia, Anna Rita (2023). Escinosome thermosensitive gel optimizes efficacy of CAI-CORM in a rat model of rheumatoid arthritis. JOURNAL OF CONTROLLED RELEASE, vol. 358, pp. 171-189, ISSN:0168-3659 DOI Accesso ONLINE all'editore

Arias, Hugo R; Tae, Han-Shen; Micheli, Laura; Yousuf, Arsalan; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Adams, David J; Di Cesare Mannelli, Lorenzo (2023). The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor. ANESTHESIA AND ANALGESIA, vol. 137, pp. 691-701, ISSN:0003-2999 DOI

Lucarini, Elena; Micheli, Laura; Rajagopalan, Raghavan; Ciampi, Clara; Branca, Jacopo Junio Valerio; Pacini, Alessandra; Leandri, Massimo; Rajagopalan, Parthasarathi; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo (2023). Broad-spectrum neuroprotection exerted by DDD-028 in a mouse model of chemotherapy-induced neuropathy. PAIN, vol. 00, pp. 0-0, ISSN:0304-3959 DOI Accesso ONLINE all'editore

Ferrara V.; Toti A.; Lucarini E.; Parisio C.; Micheli L.; Ciampi C.; Margiotta F.; Crocetti L.; Vergelli C.; Giovannoni M.P.; Di Cesare Mannelli L.; Ghelardini C. (2023). Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis. ANTIOXIDANTS, vol. 12, pp. 1207-1226, ISSN:2076-3921 DOI

Berrino, Emanuela; Micheli, Laura; Carradori, Simone; di Cesare Mannelli, Lorenzo; Guglielmi, Paolo; De Luca, Alessandro; Carta, Fabrizio; Ghelardini, Carla; Secci, Daniela; Supuran, Claudiu T (2023). Novel Insights on CAI-CORM Hybrids: Evaluation of the CO Releasing Properties and Pain-Relieving Activity of Differently Substituted Coumarins for the Treatment of Rheumatoid Arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 66, pp. 0-0, ISSN:0022-2623 DOI

Angeli A.; Micheli L.; Carta F.; Ferraroni M.; Pirali T.; Fernandez Carvajal A.; Ferrer Montiel A.; Di Cesare Mannelli L.; Ghelardini C.; Supuran C.T. (2023). First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy. JOURNAL OF MEDICINAL CHEMISTRY, vol. 66, pp. 1616-1633, ISSN:0022-2623 DOI

Micheli L.; Testai L.; Angeli A.; Carrino D.; Pacini A.; Margiotta F.; Flori L.; Supuran C.T.; Calderone V.; Ghelardini C.; Mannelli L.D.C. (2022). Inhibitors of Mitochondrial Human Carbonic Anhydrases VA and VB as a Therapeutic Strategy against Paclitaxel-Induced Neuropathic Pain in Mice. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 6229-6229, ISSN:1422-0067 DOI

Lucarini E, Di Pilato V, Parisio C, Micheli L, Toti A, Pacini A, Bartolucci G, Baldi S, Niccolai E, Amedei A, Rossolini GM, Nicoletti C, Cryan JF, O'Mahony SM, Ghelardini C, Di Cesare Mannelli L. (2022). Visceral sensitivity modulation by faecal microbiota transplantation: the active role of gut bacteria in pain persistence. PAIN, pp. 1-17, ISSN:1872-6623

Micheli L.; Parisio C.; Lucarini E.; Carrino D.; Ciampi C.; Toti A.; Ferrara V.; Pacini A.; Ghelardini C.; Di Cesare Mannelli L. (2022). Restorative and pain-relieving effects of fibroin in preclinical models of tendinopathy. BIOMÉDECINE & PHARMACOTHÉRAPIE, vol. 148, pp. 112693-112693, ISSN:0753-3322 DOI

Micheli, Laura; Lucarini, Elena; Nobili, Stefania; Bartolucci, Gianluca; Pallecchi, Marco; Toti, Alessandra; Ferrara, Valentina; Ciampi, Clara; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo (2022). Ultramicronized N-palmitoylethanolamine contributes to morphine efficacy against neuropathic pain: implication of mast cells and glia. CURRENT NEUROPHARMACOLOGY, vol. 21, pp. 0-0, ISSN:1570-159X DOI

Margiotta, Francesco; Micheli, Laura; Ciampi, Clara; Ghelardini, Carla; McIntosh, J. Michael; Di Cesare Mannelli, Lorenzo (2022). Conus regius-Derived Conotoxins: Novel Therapeutic Opportunities from a Marine Organism. MARINE DRUGS, vol. 20, pp. 0-0, ISSN:1660-3397 DOI

Lucarini E.; Micheli L.; Di Cesare Mannelli L.; Ghelardini C. (2022). Naturally occurring glucosinolates and isothiocyanates as a weapon against chronic pain: potentials and limits. PHYTOCHEMISTRY REVIEWS, vol. 21, pp. 647-665, ISSN:1568-7767 DOI

Lucarini E.; Micheli L.; Pagnotta E.; Toti A.; Ferrara V.; Ciampi C.; Margiotta F.; Martelli A.; Testai L.; Calderone V.; Matteo R.; Suriano S.; Troccoli A.; Pecchioni N.; Manera C.; Di Cesare Mannelli L.; Ghelardini C. (2022). The Efficacy of Camelina sativa Defatted Seed Meal against Colitis-Induced Persistent Visceral Hypersensitivity: The Relevance of PPAR α Receptor Activation in Pain Relief. NUTRIENTS, vol. 14, pp. 3137-3137, ISSN:2072-6643 DOI

Di Cesare Mannelli, Lorenzo; Micheli, Laura; Cervetto, Chiara; Toti, Alessandra; Lucarini, Elena; Parisio, Carmen; Marcoli, Manuela; Ghelardini, Carla (2022). Neuronal alarmin IL-1α evokes astrocyte-mediated protective signals: Effectiveness in chemotherapy-induced neuropathic pain. NEUROBIOLOGY OF DISEASE, vol. 168, pp. 105716-105716, ISSN:0969-9961 DOI

Micheli L.; Lucarini E.; Toti A.; Ferrara V.; Ciampi C.; Parisio C.; Bartolucci G.; Di Cesare Mannelli L.; Ghelardini C. (2022). Effects of Ultramicronized N-Palmitoylethanolamine Supplementation on Tramadol and Oxycodone Analgesia and Tolerance Prevention. PHARMACEUTICS, vol. 14, pp. 403-403, ISSN:1999-4923 DOI

Lucarini E.; Micheli L.; Pagnotta E.; Matteo R.; Parisio C.; Toti A.; Ferrara V.; Ciampi C.; Martelli A.; Testai L.; Calderone V.; Savino M.; Russo M.; Pecchioni N.; Ghelardini C.; Di Cesare Mannelli L. (2022). Beneficial Effects of Eruca sativa Defatted Seed Meal on Visceral Pain and Intestinal Damage Resulting from Colitis in Rats. FOODS, vol. 11, pp. 580-580, ISSN:2304-8158 DOI

Micheli, Laura; Maramai, Samuele; Toti, Alessandra; Ferrara, Valentina; Ciampi, Clara; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2022). Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 0-0, ISSN:1422-0067 DOI

Avagliano, Carmen; De Caro, Carmen; Cuozzo, Mariarosaria; Liguori, Fabrizio Maria; La Rana, Giovanna; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Paciello, Orlando; Russo, Roberto (2022). Phaseolus vulgaris extract ameliorates high-fat diet-induced colonic barrier dysfunction and inflammation in mice by regulating peroxisome proliferator-activated receptor expression and butyrate levels. FRONTIERS IN PHARMACOLOGY, vol. 13, pp. 0-0, ISSN:1663-9812 DOI

Micheli, Laura; Toti, Alessandra; Lucarini, Elena; Ferrara, Valentina; Ciampi, Clara; Olivero, Guendalina; Pittaluga, Anna; Mattoli, Luisa; Pelucchini, Caroline; Burico, Michela; Lucci, Jacopo; Carrino, Donatello; Pacini, Alessandra; Pallanti, Stefano; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2022). Efficacy of a vegetal mixture composed of Zingiber officinale, Echinacea purpurea, and Centella asiatica in a mouse model of neuroinflammation: In vivo and ex vivo analysis. FRONTIERS IN NUTRITION, vol. 9, pp. 0-0, ISSN:2296-861X DOI

Micheli, Laura; Mitidieri, Emma; Turnaturi, Carlotta; Vanacore, Domenico; Ciampi, Clara; Lucarini, Elena; Cirino, Giuseppe; Ghelardini, Carla; Sorrentino, Raffaella; Di Cesare Mannelli, Lorenzo; d'Emmanuele di Villa Bianca, Roberta (2022). Beneficial Effect of H2S-Releasing Molecules in an In Vitro Model of Sarcopenia: Relevance of Glucoraphanin. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 5955-5955, ISSN:1422-0067 DOI

Bonardi, Alessandro; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Gratteri, Paola; Nocentini, Alessio; Supuran, Claudiu T (2022). Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 65, pp. 13143-13157, ISSN:1520-4804 DOI

Vanti, Giulia; Di Cesare Mannelli, Lorenzo; Micheli, Laura; Cinci, Lorenzo; Grifoni, Lucia; Bergonzi, Maria Camilla; Ghelardini, Carla; Bilia, Anna Rita (2021). The Anti-Arthritic Efficacy of Khellin Loaded in Ascorbyl Decanoate Nanovesicles after an Intra-Articular Administration. PHARMACEUTICS, vol. 13, pp. 1275-1275, ISSN:1999-4923 DOI

Tanini D.; Carradori S.; Capperucci A.; Lupori L.; Zara S.; Ferraroni M.; Ghelardini C.; Mannelli L.D.C.; Micheli L.; Lucarini E.; Carta F.; Angeli A.; Supuran C.T. (2021). Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 225, pp. 0-0, ISSN:0223-5234 DOI

Micheli L., Parisio C., Lucarini E., Vona A., Toti A., Pacini A., Mello T., Boccella S., Ricciardi F., Maione S., Graziani G., Lacal P.M., Failli P., Ghelardini C., Di Cesare Mannelli L. (2021). VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, pp. 1-19, ISSN:1756-9966 DOI

Micheli L.; Durante M.; Lucarini E.; Sgambellone S.; Lucarini L.; Di Cesare Mannelli L.; Ghelardini C.; Masini E. (2021). The histamine h4 receptor participates in the anti-neuropathic effect of the adenosine a3 receptor agonist ib-meca: Role of cd4+ t cells. BIOMOLECULES, vol. 11, pp. 1447-1447, ISSN:2218-273X DOI

Congiu M.; Micheli L.; Santoni M.; Sagheddu C.; Muntoni A.L.; Makriyannis A.; Malamas M.S.; Ghelardini C.; Di Cesare Mannelli L.; Pistis M. (2021). N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance. NEUROTHERAPEUTICS, pp. 0-0, ISSN:1933-7213 DOI

Lucarini E., Nocentini A., Bonardi A., Chiaramonte N., Parisio C., Micheli L., Toti A., Ferrara V., Carrino D., Pacini A., Romanelli M.N., Supuran C.T., Ghelardini C., Di Cesare Mannelli L. (2021). Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats. CELLS, vol. 10, pp. 2540-2555, ISSN:2073-4409 DOI

Micheli L., Rajagopalan R., Lucarini E., Toti A., Parisio C., Carrino D., Pacini A., Ghelardini C., Rajagopalan P., Di Cesare Mannelli L. (2021). Pain Relieving and Neuroprotective Effects of Non-opioid Compound, DDD-028, in the Rat Model of Paclitaxel-Induced Neuropathy. NEUROTHERAPEUTICS, pp. 1-13, ISSN:1933-7213 DOI

Pacini A., Tomassoni D., Trallori E., Micheli L., Amenta F., Gherlardini C., Di Cesare Mannelli L., Traini E (2021). Comparative assessment of the activity of racemic and dextrorotatory forms of thioctic (alpha-lipoic) acid in low back pain: preclinical and clinical evidences, from an open randomized trial.. FRONTIERS IN PHARMACOLOGY, vol. 12, pp. 607572-607587, ISSN:1663-9812 DOI

Lucarini E.; Seguella L.; Vincenzi M.; Parisio C.; Micheli L.; Toti A.; Corpetti C.; Del Re A.; Squillace S.; Maftei D.; Lattanzi R.; Ghelardini C.; Di Cesare Mannelli L.; Esposito G. (2021). Role of enteric glia as bridging element between gut inflammation and visceral pain consolidation during acute colitis in rats. BIOMEDICINES, vol. 9, pp. 1671-1671, ISSN:2227-9059 DOI

Micheli L.; Vasarri M.; Barletta E.; Lucarini E.; Ghelardini C.; Degl'Innocenti D.; Di Cesare Mannelli L. (2021). Efficacy of Posidonia oceanica Extract against Inflammatory Pain: In Vivo Studies in Mice. MARINE DRUGS, vol. 19, pp. 48-62, ISSN:1660-3397 DOI Accesso ONLINE all'editore

Maestrelli, Francesca; González-Rodríguez, María Luisa; Fernández-Romero, Ana-María; Mura, Paola Angela; Rabasco, Antonio M.; Micheli, Laura; Mannelli, Lorenzo Di Cesare; Ghelardini, Carla (2020). Curcumin-in-Cyclodextrins-in-Liposomes: An Alternative for Osteoarthritis Treatment. PROCEEDINGS, vol. 78, pp. 0-0, ISSN:2504-3900 DOI Accesso ONLINE all'editore

Lucarini, E; Coppi, E; Micheli, L; Parisio, C; Vona, A; Cherchi, F; Pugliese, AM; Pedata, F; Failli, P; Palomino, S; Wahl, J; Largent-Milnes, TM; Vanderah, TW; Tosh, DK; Jacobson, KA; Salvemini, D; Ghelardini, C; Mannelli, LD (2020). Acute visceral pain relief mediated by A(3)AR agonists in rats: involvement of N-type voltage-gated calcium channels. PAIN, vol. 161, pp. 2179-2190, ISSN:0304-3959 DOI

De Caro, Carmen; Di Cesare Mannelli, Lorenzo; Branca, Jacopo Junio Valerio; Micheli, Laura; Citraro, Rita; Russo, Emilio; De Sarro, Giovambattista; Ghelardini, Carla; Calignano, Antonio; Russo, Roberto (2020). Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors. FRONTIERS IN PHARMACOLOGY, vol. 11, pp. 0-0, ISSN:1663-9812 DOI

Lucarini E.; Parisio C.; Branca J.J.V.; Segnani C.; Ippolito C.; Pellegrini C.; Antonioli L.; Fornai M.; Micheli L.; Pacini A.; Bernardini N.; Blandizzi C.; Ghelardini C.; Di Cesare Mannelli L. (2020). Deepening the Mechanisms of Visceral Pain Persistence: An Evaluation of the Gut-Spinal Cord Relationship. CELLS, vol. 9, pp. 0-0, ISSN:2073-4409 DOI

Bua S.; Lucarini L.; Micheli L.; Menicatti M.; Bartolucci G.; Selleri S.; Di Cesare Mannelli L.; Ghelardini C.; Masini E.; Carta F.; Gratteri P.; Nocentini A.; Supuran C.T. (2020). Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 2325-2342, ISSN:0022-2623 DOI Accesso ONLINE all'editore

Bedini A.; Di Cesare Mannelli L.; Micheli L.; Baiula M.; Vaca G.; De Marco R.; Gentilucci L.; Ghelardini C.; Spampinato S. (2020). Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist. FRONTIERS IN PHARMACOLOGY, vol. 11, pp. 0-0, ISSN:1663-9812 DOI

Micheli L.; Spitoni S.; Di Cesare Mannelli L.; Bilia A.R.; Ghelardini C.; Pallanti S. (2020). Bacopa monnieri as augmentation therapy in the treatment of anhedonia, preclinical and clinical evaluation. PHYTOTHERAPY RESEARCH, vol. 34, pp. 2331-2340, ISSN:0951-418X DOI

Arias H.R.; Tae H.-S.; Micheli L.; Yousuf A.; Ghelardini C.; Adams D.J.; Di Cesare Mannelli L. (2020). Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2.2 channels. NEUROPHARMACOLOGY, vol. 175, pp. 0-0, ISSN:0028-3908 DOI

Parisio C.; Lucarini E.; Micheli L.; Toti A.; Khatib M.; Mulinacci N.; Calosi L.; Bani D.; Mannelli L.D.C.; Ghelardini C. (2020). Pomegranate mesocarp against colitis-induced visceral pain in rats: Effects of a decoction and its fractions. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1-16, ISSN:1661-6596 DOI

Caputi F.F.; Di Cesare Mannelli L.; Rullo L.; Micheli L.; Stamatakos S.; Posa L.; Ghelardini C.; Romualdi P.; Candeletti S. (2020). The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms. BIOCHEMICAL PHARMACOLOGY, vol. 182, pp. 0-0, ISSN:0006-2952 DOI

Micheli L.; Mannelli L.D.C.; Mattoli L.; Tamimi S.; Flamini E.; Garetto S.; Lucci J.; Giovagnoni E.; Cinci L.; D'ambrosio M.; Luceri C.; Ghelardini C. (2020). Intra-articular route for the system of molecules 14g1862 from centella asiatica: Pain relieving and protective effects in a rat model of osteoarthritis. NUTRIENTS, vol. 12, pp. 0-0, ISSN:2072-6643 DOI

Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Carmen Parisio, Alessandra Toti, Bruno Fiorentino, Maria Adele Rigamonti, Laura Calosi, and Carla Ghelardini (2020). Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study. FRONTIERS IN PHARMACOLOGY, pp. 0-0, ISSN:1663-9812 DOI

Micheli L.; Di Cesare Mannelli L.; Del Bello F.; Giannella M.; Piergentili A.; Quaglia W.; Carrino D.; Pacini A.; Ghelardini C. (2020). The Use of the Selective Imidazoline I1 Receptor Agonist Carbophenyline as a Strategy for Neuropathic Pain Relief: Preclinical Evaluation in a Mouse Model of Oxaliplatin-Induced Neurotoxicity. NEUROTHERAPEUTICS, pp. 0-0, ISSN:1933-7213 DOI

Parisio C.; Lucarini E.; Micheli L.; Toti A.; Mannelli L.D.C.; Antonini G.; Panizzi E.; Maidecchi A.; Giovagnoni E.; Lucci J.; Ghelardini C. (2020). Researching new therapeutic approaches for abdominal visceral pain treatment: Preclinical effects of an assembled system of molecules of vegetal origin. NUTRIENTS, vol. 12, pp. 0-0, ISSN:2072-6643 DOI

Cirri, Marzia; Maestrelli, Francesca; Mennini, Natascia; Di Cesare Mannelli, Lorenzo; Micheli, Laura; Ghelardini, Carla; Mura, Paola (2020). Development of a stable oral pediatric solution of hydrochlorothiazide by the combined use of cyclodextrins and hydrophilic polymers. INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 587, pp. 119692-119692, ISSN:0378-5173 DOI Accesso ONLINE all'editore

Nocentini A.; Alterio V.; Bua S.; Micheli L.; Esposito D.; Buonanno M.; Bartolucci G.; Osman S.M.; Alothman Z.A.; Cirilli R.; Pierini M.; Monti S.M.; Di Cesare Mannelli L.; Gratteri P.; Ghelardini C.; De Simone G.; Supuran C.T. (2020). Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 5185-5200, ISSN:0022-2623 DOI

Di Cesare Mannelli L.; Micheli L.; Lucarini E.; Parisio C.; Toti A.; Tenci B.; Zanardelli M.; Branca J.J.V.; Pacini A.; Ghelardini C. (2020). Effects of the combination of β-hydroxy-β-methyl butyrate and R(+) lipoic acid in a cellular model of sarcopenia. MOLECULES, vol. 25, pp. 1-18, ISSN:1420-3049 DOI

Laura Micheli, Alessandra Pacini, Lorenzo Di Cesare Mannelli, Elena Trallori, Carla Ghelardini (2020). Treatment of Non-Alcoholic Steatosis: Preclinical Study of a New Nutraceutical Multitarget Formulation.. NUTRIENTS, vol. 12, pp. 1819-1842, ISSN:2072-6643 DOI

Parisio C.; Lucarini E.; Micheli L.; Toti A.; Bellumori M.; Cecchi L.; Calosi L.; Bani D.; Di Cesare Mannelli L.; Mulinacci N.; Ghelardini C. (2020). Extra virgin olive oil and related by-products (: Olea europaea L.) as natural sources of phenolic compounds for abdominal pain relief in gastrointestinal disorders in rats. FOOD & FUNCTION, vol. 11, pp. 10423-10435, ISSN:2042-6496 DOI Accesso ONLINE all'editore

Lucarini E, Pagnotta E, Micheli L, Parisio C, Testai L, Martelli A, Calderone V, Matteo R, Lazzeri L, Di Cesare Mannelli L, Ghelardini C (2019). Eruca sativa Meal against Diabetic Neuropathic Pain: An H2S-Mediated Effect of Glucoerucin. MOLECULES, pp. 0-0, ISSN:1420-3049 DOI

Micheli L.; Bozdag M.; Akgul O.; Carta F.; Guccione C.; Bergonzi M.C.; Bilia A.R.; Cinci L.; Lucarini E.; Parisio C.; Supuran C.T.; Ghelardini C.; Di Cesare Mannelli L. (2019). Pain relieving effect of-NSAIDS-CAIs hybrid molecules: Systemic and intra-articular treatments against rheumatoid arthritis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 1923-1938, ISSN:1422-0067 DOI Accesso ONLINE all'editore

Micheli L, Lucarini E, Trallori E, Avagliano C, De Caro C, Russo R, Calignano A, Ghelardini C, Pacini A, Di Cesare Mannelli L. (2019). Phaseolus vulgaris L. Extract: Alpha-Amylase Inhibition against Metabolic Syndrome in Mice .. NUTRIENTS, vol. 11, pp. 1778-1797, ISSN:2072-6643 DOI

Micheli L, Cialdai F, Pacini A, Branca JJV, Morbidelli L, Ciccone V, Lucarini E, Ghelardini C, Monici M, Di Cesare Mannelli L (2019). Effect of NIR laser therapy by MLS-MiS source against neuropathic pain in rats: in vivo and ex vivo analysis.. SCIENTIFIC REPORTS, vol. 9, pp. 9297-9306, ISSN:2045-2322 DOI

Laura Micheli, Murat Bozdag , Ozlem Akgul , Fabrizio Carta , Clizia Guccione, Maria Camilla Bergonzi, Anna Rita Bilia, Lorenzo Cinci, Elena Lucarini, Carmen Parisio, Claudiu T. Supuran , Carla Ghelardini, Lorenzo Di Cesare Mannelli (2019). Pain Relieving Eect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, pp. 0-0, ISSN:1422-0067

Berrino E.; Milazzo L.; Micheli L.; Vullo D.; Angeli A.; Bozdag M.; Nocentini A.; Menicatti M.; Bartolucci G.; Di Cesare Mannelli L.; Ghelardini C.; Supuran C.T.; Carta F. (2019). Synthesis and evaluation of carbonic anhydrase inhibitors with carbon monoxide releasing properties for the management of rheumatoid arthritis. JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, pp. 7233-7249, ISSN:1520-4804 DOI

Piazzini, Vieri; Micheli, Laura; Luceri, Cristina; D'Ambrosio, Mario; Cinci, Lorenzo; Ghelardini, Carla; Rita Bilia, Anna; Di Cesare Mannelli, Lorenzo; Camilla Bergonzi, Maria (2019). Nanostructured lipid carriers for oral delivery of silymarin: improving its absorption and in vivo efficacy in type 2 diabetes and metabolic syndrome model. INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. ---, pp. 0-0, ISSN:0378-5173 DOI Accesso ONLINE all'editore

Micheli L, Ghelardini C, Lucarini E, Parisio C, Trallori E, Cinci L, Di Cesare Mannelli L (2019). Intra-articular mucilages: behavioural and histological evaluations for a new model of articular pain.. JOURNAL OF PHARMACY AND PHARMACOLOGY, pp. 971-981, ISSN:0022-3573 DOI

Micheli L., Mattoli L., Maidecchi A., Pacini A., Ghelardini C., Di Cesare Mannelli L. (2018). Effect of Vitis vinifera hydroalcoholic extract against oxaliplatin neurotoxicity: in vitro and in vivo evidence. SCIENTIFIC REPORTS, vol. 8, pp. 14364-14377, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Resta, F.*; Micheli, L.; Laurino, A.; Spinelli, V.; Mello, T.; Sartiani, L.; Di Cesare Mannelli, L.; Cerbai, E.; Ghelardini, C.; Romanelli, M.N.; Mannaioni, G.; Masi, A. (2018). Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy. NEUROPHARMACOLOGY, vol. 131, pp. 403-413, ISSN:0028-3908 DOI Accesso ONLINE all'editore

Lucarini E, Micheli L, Trallori E, Citi V, Martelli A, Testai L, De Nicola G, Iori R, Calderone V, Ghelardini C, Di Cesare Mannelli L (2018). Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H2 S release in vivo.. PHYTOTHERAPY RESEARCH, pp. 2226-2234, ISSN:1099-1573 DOI

Di Cesare Mannelli L, Micheli L, Lucarini E, Ghelardini C (2018). Ultramicronized N-Palmitoylethanolamine Supplementation for Long-Lasting, Low-Dosed Morphine Antinociception. FRONTIERS IN PHARMACOLOGY, pp. 0-0, ISSN:1663-9812 DOI

Lucarini E, Micheli L, Martelli A, Testai L, Calderone V, Ghelardini C, Di Cesare Mannelli L (2018). Efficacy of isothiocyanate-based compounds on different forms of persistent pain.. JOURNAL OF PAIN RESEARCH, pp. 2905-2913, ISSN:1178-7090 DOI

Micheli L, Lucarini E, Corti F, Ciccocioppo r, Calò G, Rizzi A, Ghelardini C, Di Cesare Mannelli L. (2018). Involvement of the N/OFQ-NOP system in rat morphine antinociceptive tolerance: Are astrocytes the crossroad?. EUROPEAN JOURNAL OF PHARMACOLOGY, pp. 79-86, ISSN:0014-2999 DOI

Dietis N; Niwa H; Tose R; McDonald J; Ruggieri V; Filaferro M; Vitale G; Micheli L;Ghelardini C;Salvadori S; Calo G; Guerrini R; Rowbotham DJ; Lambert DG (2018). In vitro and in vivo characterization of the bifunctional u and o opioid receptor ligand UFP-505. BRITISH JOURNAL OF PHARMACOLOGY, pp. 2881-2896, ISSN:1476-5381 DOI

Di Cesare Mannelli, L; Pacini, A; Micheli, L; Femia, Ap; Maresca, M; Zanardelli, M; Vannacci, A; Gallo, E; Bilia, Ar; Caderni, G; Firenzuoli, F; Mugelli, A; Ghelardini, C (2017). Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?. SCIENTIFIC REPORTS, vol. 7, pp. 1-13, ISSN:2045-2322 DOI

Di Cesare Mannelli, L; Tenci, B; Micheli, L; Vona, A; Corti, F; Zanardelli, M; Lapucci, A; Clemente, Am; Failli, P; Ghelardini, C. (2017). Adipose-derived stem cells decrease pain in a rat model of oxaliplatin-induced neuropathy: Role of VEGF-A modulation. NEUROPHARMACOLOGY, pp. 166-175, ISSN:1873-7064 DOI

Lorenzo Di Cesare Mannelli, ; Mario, Maresca; Laura, Micheli; Carlo, Farina; Michael, W; Carla, Ghelardini (2017). A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin. CANCER CHEMOTHERAPY AND PHARMACOLOGY, pp. 1091-1103, ISSN:0344-5704 DOI

Maresca, M; Micheli, L; Cinci, L; Bilia, Ar; Ghelardini, C; Di Cesare Mannelli, L. (2017). Pain relieving and protective effects of Astragalus hydroalcoholic extract in rat arthritis models. JOURNAL OF PHARMACY AND PHARMACOLOGY, pp. 1858-1870, ISSN:0022-3573 DOI

Tenci, B; Di Cesare Mannelli, L; Maresca, M; Micheli, L; Pieraccini, G; Mulinacci, N; Ghelardini, C. (2017). Effects of a water extract of Lepidium meyenii root in different models of persistent pain in rats. ZEITSCHRIFT FUR NATURFORSCHUNG. C, A JOURNAL OF BIOSCIENCES, pp. 449-457, ISSN:1865-7125 DOI

Micheli, L; Di Cesare Mannelli, L; Lucarini, E; Cialdai, F; Vignali, L; Ghelardini, C; Monici, M. (2017). Photobiomodulation therapy by NIR laser in persistent pain: an analytical study in the rat. LASERS IN MEDICAL SCIENCE, pp. 1835-1846, ISSN:1435-604X DOI

Chelini, A; Brogi, S; Paolino, M; Di Capua, A; Cappelli, A; Giorgi, G; Farzad, M; Di Cesare Mannelli, L; Micheli, L; Ghelardini, C; Anzini, (2017). Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators. JOURNAL OF MEDICINAL CHEMISTRY, pp. 5216-5221, ISSN:0022-2623 DOI

Di Cesare Mannelli, L; Lucarini, E; Micheli, L; Mosca, I; Ambrosino, P; Soldovieri, Mv; Martelli, A; Testai, L; Taglialatela, M; Calderone, V; Ghelardini, C. (2017). Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels. NEUROPHARMACOLOGY, pp. 49-59, ISSN:1873-7064 DOI

Di Cesare Mannelli, Lorenzo; Micheli, Laura; Crocetti, Letizia; Giovannoni, Maria Paola; Vergelli, Claudia; Ghelardini, Carla (2017). α2 Adrenoceptor: a Target for Neuropathic Pain Treatment. MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol. 16, pp. 95-107, ISSN:1875-5607 DOI

Di Cesare Mannelli, L; Ghelardini, C; Micheli, L; Del Bello, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W. (2017). Synergic stimulation of serotonin 5-HT1A receptor and α2-adrenoceptors for neuropathic pain relief: Preclinical effects of 2-substituted imidazoline derivatives. EUROPEAN JOURNAL OF PHARMACOLOGY, pp. 128-133, ISSN:0014-2999 DOI

Del Bello, Fabio; Cilia, Antonio; Carrieri, Antonio; Fasano, Domenico Claudio; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Micheli, Laura; Santini, Carlo; Diamanti, Eleonora; Giannella, Mario; Giorgioni, Gianfabio; Mammoli, Valerio; Paoletti, Corinne Dalila; Petrelli, Riccardo; Piergentili, Alessandro; Quaglia, Wilma; Pigini, Maria (2016). The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor. CHEMMEDCHEM, vol. 11, pp. 2287-2298, ISSN:1860-7179 DOI Accesso ONLINE all'editore

Bianchi, Enrica; Di Cesare Mannelli, Lorenzo; Micheli, Laura; Farzad, Mersedez; Aglianò, Margherita; Ghelardini, Carla (2016). Apoptotic Process Induced by Oxaliplatin in Rat Hippocampus Causes Memory Impairment. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, pp. 1-8, ISSN:1742-7835 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, Lorenzo; Micheli, Laura; Maresca, Mario; Cravotto, Giancarlo; Bellumori, Maria; Innocenti, Marzia; Mulinacci, Nadia; Ghelardini, Carla (2016). Anti-neuropathic effects of Rosmarinus officinalis L. terpenoid fraction: Relevance of nicotinic receptors. SCIENTIFIC REPORTS, vol. 6, pp. 1-15, ISSN:2045-2322 DOI

Pacini, A; Micheli, L; Maresca, M; Branca, Jj; Mcintosh, Jm; Ghelardini, C; Di Cesare Mannelli, L. (2016). The α9α10 nicotinic receptor antagonist α-conotoxin RgIA prevents neuropathic pain induced by oxaliplatin treatment.. EXPERIMENTAL NEUROLOGY, vol. 282, pp. 37-48, ISSN:0014-4886 DOI

Bird, Mark F.; Camilla Cerlesi, Maria; Brown, Mark; Malfacini, Davide; Vezzi, Vanessa; Molinari, Paola; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Guerrini, Remo; Calò, Girolamo; Lambert, David G. (2016). Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo). PLOS ONE, vol. 11 - e0156897, pp. 1-22, ISSN:1932-6203 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, L; Micheli, L; Cinci, L; Maresca, M; Vergelli, C; Pacini, A; Quinn, M.T.; Giovannoni, M. P.; Ghelardini, C. (2016). Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis.. RHEUMATOLOGY, vol. 55, pp. 1285-1294, ISSN:1462-0332 DOI

Grassi, Giacomo; Laura, Micheli; Lorenzo, Di Cesare Mannelli; Elisa, Compagno; Lorenzo, Righi; Carla, Ghelardini; Stefano, Pallanti (2016). Atomoxetine for hoarding disorder: A pre-clinical and clinical investigation. JOURNAL OF PSYCHIATRIC RESEARCH, vol. 83, pp. 240-248, ISSN:0022-3956 DOI Accesso ONLINE all'editore

Maresca, Mario; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Innocenti, Marzia; Khatib, Mohamad; Mulinacci, Nadia; Ghelardini, Carla (2016). Acute effect of Capparis spinosa root extracts on rat articular pain. JOURNAL OF ETHNOPHARMACOLOGY, vol. 193, pp. 456-465, ISSN:0378-8741 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, Lorenzo; Marcoli, Manuela; Micheli, Laura; Zanardelli, Matteo; Maura, Guido; Ghelardini, Carla; Cervetto, Chiara (2015). Oxaliplatin evokes P2X7-dependent glutamate release in the cerebral cortex: A pain mechanism mediated by Pannexin 1. NEUROPHARMACOLOGY, vol. 97, pp. 133-41-141, ISSN:0028-3908 DOI

Micheli, Laura; Di Cesare Mannelli, Lorenzo; Rizzi, Anna; Guerrini, Remo; Trapella, Claudio; Calò, Girolamo; Ghelardini, Carla (2015). Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 766, pp. 155-162, ISSN:0014-2999 DOI Accesso ONLINE all'editore

Micheli, Laura; Di Cesare Mannelli, Lorenzo; Guerrini, Remo; Trapella, Claudio; Zanardelli, Matteo; Ciccocioppo, Roberto; Rizzi, Anna; Ghelardini, Carla; Calò, Girolamo (2015). Acute and subchronic antinociceptive effects of nociceptin/orphanin FQ receptor agonists infused by intrathecal route in rats. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 754, pp. 73-81, ISSN:0014-2999 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, Lorenzo; Corti, Francesca; Micheli, Laura; Zanardelli, Matteo; Ghelardini, Carla (2015). Delay of morphine tolerance by palmitoylethanolamide. BIOMED RESEARCH INTERNATIONAL, vol. 2015, pp. 1-12, ISSN:2314-6133 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, Lorenzo; Micheli, Laura; Ghelardini, Carla (2015). Nociceptin/orphanin FQ receptor and pain: Feasibility of the fourth opioid family member. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 766, pp. 151-4-154, ISSN:0014-2999 DOI

Zanardelli, Matteo; Micheli, Laura; Nicolai, Raffaella; Failli, Paola; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo (2015). Different apoptotic pathways activated by oxaliplatin in primary astrocytes vs. colo-rectal cancer cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 16, pp. 5386-5399, ISSN:1661-6596 DOI Accesso ONLINE all'editore

Cinci, Lorenzo; Corti, Francesca; Di Cesare Mannelli, Lorenzo; Micheli, Laura; Zanardelli, Matteo; Ghelardini, Carla (2015). Oxidative, Metabolic, And Apoptotic Responses of Schwann Cells to High Glucose Levels. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, vol. 29, pp. 274-279, ISSN:1095-6670 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, Lorenzo; Micheli, Laura; Carta, Fabrizio; Cozzi, Andrea; Ghelardini, Carla; Supuran, Claudiu T (2015). Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, pp. 1-6, ISSN:1475-6366 DOI

Pacini A; Micheli L; Di Cesare Mannelli L; Mugelli A; Ghelardini C (2014). Astragalus membranaceus and oxaliplatin-induced neuropathy: pain relief and prevention of nervous tissue modifications.. ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY, vol. 119, pp. 147-147, ISSN:1122-6714

Di Cesare Mannelli L.; Pacini A.; Micheli L.; Tani A.; Zanardelli M.; Ghelardini C. (2014). Glia role in oxaliplatin-induced neuropathic pain.. EXPERIMENTAL NEUROLOGY, vol. 261C, pp. 22-33, ISSN:0014-4886 DOI

Baptista-De Souza D; Di Cesare Mannelli L; Zanardelli M; Micheli L; Nunes-De Souza RL; Canto-De Souza A; Ghelardini C (2014). Serotonergic modulation in neuropathy induced by oxaliplatin: Effect on the 5HT2C receptor. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 735, pp. 141-149, ISSN:0014-2999 DOI

L. Cinci;L. Di Cesare Mannelli;M. Zanardelli;L. Micheli;D. Guasti;C. Ghelardini (2014). Peroxisome determination in optical microscopy: a useful tool derived by a simplification of an old ultrastructural technique.. ACTA HISTOCHEMICA, vol. 116, pp. 863-870, ISSN:0065-1281 DOI Accesso ONLINE all'editore

Di Cesare Mannelli, L; Zanardelli, M; Micheli, L; Ghelardini, C (2014). PPAR-γ Impairment Alters Peroxisome Functionality in Primary Astrocyte Cell Cultures. BIOMED RESEARCH INTERNATIONAL, pp. 0-0, ISSN:2314-6141 DOI

Zanardelli, M; Micheli, L; Cinci, L; Failli, P; Ghelardini, C; Di Cesare Mannelli, L (2014). Oxaliplatin Neurotoxicity Involves Peroxisome Alterations. PPARc Agonism as Preventive Pharmacological Approach. PLOS ONE, vol. 9, pp. 0-0, ISSN:1932-6203 DOI

Di Cesare Mannelli L; Cinci L; Micheli L; Zanardelli M; Pacini A; McIntosh JM; Ghelardini C (2014). alpha-Conotoxin RgIA protects against the development of nerve injury-induced chronic pain and prevents both neuronal and glial derangement.. PAIN, vol. 155, pp. 1986-1995, ISSN:0304-3959 DOI

Di Cesare Mannelli L; Micheli L; Zanardelli M; Ghelardini C (2013). Low dose native type II collagen prevents pain in a rat osteoarthritis model. BMC MUSCULOSKELETAL DISORDERS, vol. 14, pp. 228-235, ISSN:1471-2474 DOI