Alessia VIGNOLI

Ruolo attuale:: Ricercatore Legge 240/10 a tempo determinato
SSD:: CHEM-03/A - Chimica generale e inorganica
Afferenza organizzativa:: Dipartimento di Chimica 'Ugo Schiff' - DICUS

Recapiti

alessia.vignoli(AT)unifi.it

Alessia VIGNOLI

Biografia

Alessia Vignoli ha conseguito la laurea magistrale in Scienze Chimiche cum laude (curriculum: Chimica delle Molecole Biologiche) presso l'Università di Firenze nel 2014. Nello stesso anno ha vinto una borsa di dottorato per il Dottorato Internazionale in Biologia Strutturale presso la stessa Università, ottenendo il titolo di Dottore di Ricerca cum laude nel 2017.

Nel 2018 è stata ricercatrice post-dottorato sotto la supervisione del Prof. Luchinat presso il CERM/CIRMMP e, tra il 2019 e il 2020, ha ricevuto una AIRC fellowship per il suo progetto "METabolomic profile as a prognostic biomarker of risk of recurrence in patients operated for COLon cancer (METCOL)". Sotto la guida del Prof. Leonardo Tenori, ha lavorato come assegnista di ricerca post-dottorato (2021-2022) presso il Dipartimento di Chimica dell'Università di Firenze. Nel 2023 è entrata a far parte del corpo docente dello stesso Dipartimento come ricercatrice a tempo determinato.

Alessia VIGNOLI

Curriculum

Istruzione e Formazione

Diploma di Maturità Scientifica P.N.I. – 2007
Laurea Triennale in Chimica (Classe – 21) – Università degli Studi di Firenze – 2011 – “Sintesi di peptidi della gliadina e della trasglutamminasi tissutale per lo studio della risposta anticorpale nella celiachia”, Relatore: Prof.ssa Anna Maria Papini.
Laurea in Scienze Chimiche (LM-54) – Università degli Studi di Firenze – 2014 – “Applicazioni della Metabolomica in Biomedicina: studio longitudinale prospettico di pazienti affetti da BroncoPneumopatia Cronica Ostruttiva (BPCO)”, Relatore: Prof. Claudio Luchinat.
International Doctorate in Structural Biology – Università degli Studi di Firenze – 2017 – “Applications of Metabolomics in Biomedicine”, Relatore: Prof. Claudio Luchinat.
Percorso Formativo da 24 CFU nelle discipline antropo-psico-pedagogiche e nelle metodologie e tecnologie didattiche – Università degli Studi di Firenze – 2018

Esperienze Lavorative

Ricercatore a Tempo Determinato di tipo A (RTD-A), SDG 03/CHEM-03, SSD CHEM-03/A – Dipartimento di Chimica “Ugo Schiff”, Università degli Studi di Firenze – da Febbraio 2023
Assegnista Post-Dottorato – Dipartimento di Chimica “Ugo Schiff”, Università degli Studi di Firenze – Responsabile Scientifico: Dr. Leonardo Tenori, Ricerca Scientifica (SSD CHEM-03/A) – 2021-2023
Borsista Post-Dottorato per Fondazione AIRC per la Ricerca sul Cancro – Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine (CIRMMP) – Responsabile Scientifico: Prof. Claudio Luchinat – 2019-2020
Ricercatrice Post-Dottorato – Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine (CIRMMP) – Responsabile Scientifico: Prof. Claudio Luchinat – 2017-2018
Borsista Pre-Dottorato – Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine (CIRMMP) – Responsabile Scientifico: Prof. Claudio Luchinat – 2014

Finanziamenti e Grants

FIS 2 Starting Grant
Airalzh (Associazione Italiana Ricerca Alzheimer Onlus) Grant for Young Researchers - AGYR 2022
2-years AIRC Fellowship "Eduardo Spinnato"

Premi e Qualifiche

GIDRM Under 35 award – 2022
Abilitazione Scientifica Nazionale di seconda fascia in CHIM/03 Chimica Generale e Inorganica – 2022
Best Poster Award (translational category), al COSA's 43rd and ANZBCTG's 38^th Annual Scientific Meetings (Gold Coast Convention and Exhibition Centre, Queensland) – 2016

Produzione scientifica

Scopus: 57190191512

ORCID: 0000-0003-4038-6596

Alessia VIGNOLI

Interessi

Le aree di interesse scientifico della Dr.ssa Vignoli sono concentrate sulla caratterizzazione della composizione chimica di matrici complesse come i biofluidi mediante la spettroscopia di risonanza magnetica nucleare (NMR), e sulle applicazioni della metabolomica basata sulla tecnica NMR in medicina a scopo diagnostico e prognostico.

Alessia VIGNOLI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Vignoli, A; Luchinat, C; Segata, N; Renzi, D; Tenori, L; Calabrò, AS (2025). Serum metabolomics and lipoproteomics discriminate celiac disease and non-celiac gluten sensitivity patients. CLINICAL NUTRITION, vol. 45, pp. 31-35, ISSN:0261-5614 DOI

Vignoli, A; Bellomo, G; Paoletti, FP; Luchinat, C; Tenori, L; Parnetti, L (2025). Studying Alzheimer's disease through an integrative serum metabolomic and lipoproteomic approach. JOURNAL OF TRANSLATIONAL MEDICINE, vol. 23, pp. 0-0, ISSN:1479-5876 DOI

Basoglu, Abdullah; ABDEL-AZIZ ADAM, ADAM; BASPINAR, NURI; VIGNOLI, ALESSIA; MEONI, GAIA; Tenori, Leonardo; Gullersoy, Erdem; Bicici, Rumeyhisa (2024). EFFECTS of BORON SUPPLEMENTATION on DAIRY CALVES’ HEALTH: A METABOLOMICS STUDY. ASSIUT VETERINARY MEDICAL JOURNAL, vol. 70, pp. 10-25, ISSN:2314-5226 DOI

Vignoli, Alessia; Gori, Anna Maria; Berteotti, Martina; Cesari, Francesca; Giusti, Betti; Bertelli, Alessia; Kura, Ada; Sticchi, Elena; Salvadori, Emilia; Barbato, Carmen; Formelli, Benedetta; Pescini, Francesca; Marcucci, Rossella; Tenori, Leonardo; Poggesi, Anna (2024). The serum metabolomic profiles of atrial fibrillation patients treated with direct oral anticoagulants or vitamin K antagonists. LIFE SCIENCES, vol. 351, pp. 0-0, ISSN:0024-3205 DOI

Di Nisio, Andrea; De Toni, Luca; Sabovic, Iva; Vignoli, Alessia; Tenori, Leonardo; Dall’Acqua, Stefano; Sut, Stefania; La Vignera, Sandro; Condorelli, Rosita Angela; Giacone, Filippo; Ferlin, Alberto; Foresta, Carlo; Garolla, Andrea (2024). Lipidomic Profile of Human Sperm Membrane Identifies a Clustering of Lipids Associated with Semen Quality and Function. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 25, pp. N/A-N/A, ISSN:1422-0067 DOI

Vignoli, Alessia; Takis, Panteleimon; Montuschi, Paolo (2023). Editorial: Pharmacometabolomics: biomarker discovery, precision medicine, technical advances, perspectives and future applications in respiratory diseases. FRONTIERS IN MOLECULAR BIOSCIENCES, vol. 10, pp. N/A-N/A, ISSN:2296-889X DOI

Di Cesare, Alessia Vignoli, Claudio Luchinat, Tenori Leonardo, Saccenti Edoardo (2023). Exploration of Blood Metabolite Signatures of Colorectal Cancer and Polyposis through Integrated Statistical and Network Analysis. METABOLITES, pp. 0-0, ISSN:2218-1989 DOI

Risi, Emanuela; Lisanti, Camilla; Vignoli, Alessia; Biagioni, Chiara; Paderi, Agnese; Cappadona, Silvia; Monte, Francesca Del; Moretti, Erica; Sanna, Giuseppina; Livraghi, Luca; Malorni, Luca; Benelli, Matteo; Puglisi, Fabio; Luchinat, Claudio; Tenori, Leonardo; Biganzoli, Laura (2023). Risk assessment of disease recurrence in early breast cancer: A serum metabolomic study focused on elderly patients. TRANSLATIONAL ONCOLOGY, vol. 27, pp. 101585-101585, ISSN:1936-5233 DOI

Vignoli, Alessia; Miolo, Gianmaria; Tenori, Leonardo; Buonadonna, Angela; Lombardi, Davide; Steffan, Agostino; Scalone, Simona; Luchinat, Claudio; Corona, Giuseppe (2023). Novel metabolomics-biohumoral biomarkers model for predicting survival of metastatic soft-tissue sarcomas. ISCIENCE, vol. 26, pp. 107678-107678, ISSN:2589-0042 DOI

Ghini, Veronica; Meoni, Gaia; Vignoli, Alessia; Di Cesare, Francesca; Tenori, Leonardo; Turano, Paola; Luchinat, Claudio (2023). Fingerprinting and profiling in metabolomics of biosamples. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, vol. 138-139, pp. 105-135, ISSN:0079-6565 DOI

Vignoli, Alessia; Tenori, Leonardo (2023). NMR-based metabolomics in Alzheimer’s disease research: a review. FRONTIERS IN MOLECULAR BIOSCIENCES, vol. 10, pp. N/A-N/A, ISSN:2296-889X DOI

Vignoli, Alessia; Meoni, Gaia; Ghini, Veronica; Di Cesare, Francesca; Tenori, Leonardo; Luchinat, Claudio; Turano, Paola (2023). NMR-Based Metabolomics to Evaluate Individual Response to Treatments. In: Alessia Vignoli, Gaia Meoni, Veronica Ghini, Francesca Di Cesare, Leonardo Tenori, Claudio Luchinat, Paola Turano. Handbook of Experimental Pharmacology, pp. 0-0 Springer. DOI

Vignoli A.; Tenori L.; Luchinat C. (2022). An omics approach to study trace metals in sera of hemodialysis patients treated with erythropoiesis stimulating agents. METALLOMICS, vol. 14, pp. 0-0, ISSN:1756-591X DOI Accesso ONLINE all'editore

Vignoli A.; Tenori L.; Morsiani C.; Turano P.; Capri M.; Luchinat C. (2022). Serum or Plasma (and Which Plasma), That Is the Question. JOURNAL OF PROTEOME RESEARCH, vol. 21, pp. 1061-1072, ISSN:1535-3893 DOI

Vignoli A.; Fornaro A.; Tenori L.; Castelli G.; Cecconi E.; Olivotto I.; Marchionni N.; Alterini B.; Luchinat C. (2022). Metabolomics Fingerprint Predicts Risk of Death in Dilated Cardiomyopathy and Heart Failure. FRONTIERS IN CARDIOVASCULAR MEDICINE, vol. 9, pp. 851905-851905, ISSN:2297-055X DOI

Vignoli, Alessia; Meoni, Gaia; Tenori, Leonardo (2022). Applications and Challenges for Metabolomics via Nuclear Magnetic Resonance Spectroscopy. APPLIED SCIENCES, vol. 12, pp. 4655-4655, ISSN:2076-3417 DOI

Zinga, Maria Mgella; Abdel-Shafy, Ebtesam; Melak, Tadele; Vignoli, Alessia; Piazza, Silvano; Zerbini, Luiz Fernando; Tenori, Leonardo; Cacciatore, Stefano (2022). KODAMA exploratory analysis in metabolic phenotyping. FRONTIERS IN MOLECULAR BIOSCIENCES, vol. 9, pp. 1070394-1070394, ISSN:2296-889X DOI

Bendinelli B.; Vignoli A.; Palli D.; Assedi M.; Ambrogetti D.; Luchinat C.; Caini S.; Saieva C.; Turano P.; Masala G. (2021). Prediagnostic circulating metabolites in female breast cancer cases with low and high mammographic breast density. SCIENTIFIC REPORTS, vol. 11, pp. 13025-13025, ISSN:2045-2322 DOI

Balder Y.; Vignoli A.; Tenori L.; Luchinat C.; Saccenti E. (2021). Exploration of blood lipoprotein and lipid fraction profiles in healthy subjects through integrated univariate, multivariate, and network analysis reveals association of lipase activity and cholesterol esterification with sex and age. METABOLITES, vol. 11, pp. 326-326, ISSN:2218-1989 DOI

Corona G.; Di Gregorio E.; Vignoli A.; Muraro E.; Steffan A.; Miolo G. (2021). 1H-NMR plasma lipoproteins profile analysis reveals lipid metabolism alterations in HER2-positive breast cancer patients. CANCERS, vol. 13, pp. 5845-5845, ISSN:2072-6694 DOI

Vignoli A.; Mori E.; Di Donato S.; Malorni L.; Biagioni C.; Benelli M.; Calamai V.; Cantafio S.; Parnofiello A.; Baraghini M.; Garzi A.; Del Monte F.; Romagnoli D.; Migliaccio I.; Luchinat C.; Tenori L.; Biganzoli L. (2021). Exploring serum nmr-based metabolomic fingerprint of colorectal cancer patients: Effects of surgery and possible associations with cancer relapse. APPLIED SCIENCES, vol. 11, pp. 11120-11120, ISSN:2076-3417 DOI

Vignoli A.; Risi E.; McCartney A.; Migliaccio I.; Moretti E.; Malorni L.; Luchinat C.; Biganzoli L.; Tenori L. (2021). Precision oncology via nmr-based metabolomics: A review on breast cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 4687-4687, ISSN:1661-6596 DOI

Tsopra R.; Fernandez X.; Luchinat C.; Alberghina L.; Lehrach H.; Vanoni M.; Dreher F.; Sezerman O.U.; Cuggia M.; de Tayrac M.; Miklasevics E.; Itu L.M.; Geanta M.; Ogilvie L.; Godey F.; Boldisor C.N.; Campillo-Gimenez B.; Cioroboiu C.; Ciusdel C.F.; Coman S.; Hijano Cubelos O.; Itu A.; Lange B.; Le Gallo M.; Lespagnol A.; Mauri G.; Soykam H.O.; Rance B.; Turano P.; Tenori L.; Vignoli A.; Wierling C.; Benhabiles N.; Burgun A. (2021). A framework for validating AI in precision medicine: considerations from the European ITFoC consortium. BMC MEDICAL INFORMATICS AND DECISION MAKING, vol. 21, pp. 274-274, ISSN:1472-6947 DOI

Meoni, Gaia; Ghini, Veronica; Maggi, Laura; Vignoli, Alessia; Mazzoni, Alessio; Salvati, Lorenzo; Capone, Manuela; Vanni, Anna; Tenori, Leonardo; Fontanari, Paolo; Lavorini, Federico; Peris, Adriano; Bartoloni, Alessandro; Liotta, Francesco; Cosmi, Lorenzo; Luchinat, Claudio; Annunziato, Francesco; Turano, Paola (2021). Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab. PLOS PATHOGENS, vol. 17, pp. e1009243-e1009243, ISSN:1553-7374 DOI

Di Donato S.; Vignoli A.; Biagioni C.; Malorni L.; Mori E.; Tenori L.; Calamai V.; Parnofiello A.; Di Pierro G.; Migliaccio I.; Cantafio S.; Baraghini M.; Mottino G.; Becheri D.; Del Monte F.; Miceli E.; McCartney A.; Di Leo A.; Luchinat C.; Biganzoli L. (2021). A serum metabolomics classifier derived from elderly patients with metastatic colorectal cancer predicts relapse in the adjuvant setting. CANCERS, vol. 13, pp. 2762-2762, ISSN:2072-6694 DOI

Vignoli A.; Tenori L.; Giusti B.; Valente S.; Carrabba N.; Balzi D.; Barchielli A.; Marchionni N.; Gensini G.F.; Marcucci R.; Gori A.M.; Luchinat C.; Saccenti E. (2020). Differential Network Analysis Reveals Metabolic Determinants Associated with Mortality in Acute Myocardial Infarction Patients and Suggests Potential Mechanisms Underlying Different Clinical Scores Used to Predict Death. JOURNAL OF PROTEOME RESEARCH, vol. 19, pp. 949-961, ISSN:1535-3893 DOI

Vignoli A.; Muraro E.; Miolo G.; Tenori L.; Turano P.; Di Gregorio E.; Steffan A.; Luchinat C.; Corona G. (2020). Effect of estrogen receptor status on circulatory immune and metabolomics profiles of her2-positive breast cancer patients enrolled for neoadjuvant targeted chemotherapy. CANCERS, vol. 12, pp. 0-0, ISSN:2072-6694 DOI

Rocca M.S.; Vignoli A.; Tenori L.; Ghezzi M.; De Rocco Ponce M.; Vatsellas G.; Thanos D.; Padrini R.; Foresta C.; De Toni L. (2020). Evaluation of Serum/Urine Genomic and Metabolomic Profiles to Improve the Adherence to Sildenafil Therapy in Patients with Erectile Dysfunction. FRONTIERS IN PHARMACOLOGY, vol. 11, pp. 0-0, ISSN:1663-9812 DOI

Vignoli A.; Tenori L.; Luchinat C.; Saccenti E. (2020). Differential Network Analysis Reveals Molecular Determinants Associated with Blood Pressure and Heart Rate in Healthy Subjects. JOURNAL OF PROTEOME RESEARCH, vol. 20, pp. 1040-1051-1051, ISSN:1535-3893 DOI

Vignoli A.; Santini G.; Tenori L.; Macis G.; Mores N.; Macagno F.; Pagano F.; Higenbottam T.; Luchinat C.; Montuschi P. (2020). NMR-Based Metabolomics for the Assessment of Inhaled Pharmacotherapy in Chronic Obstructive Pulmonary Disease Patients. JOURNAL OF PROTEOME RESEARCH, vol. 19, pp. 64-74, ISSN:1535-3893 DOI

Vignoli A.; Paciotti S.; Tenori L.; Eusebi P.; Biscetti L.; Chiasserini D.; Scheltens P.; Turano P.; Teunissen C.; Luchinat C.; Parnetti L. (2020). Fingerprinting Alzheimer's Disease by 1H Nuclear Magnetic Resonance Spectroscopy of Cerebrospinal Fluid. JOURNAL OF PROTEOME RESEARCH, vol. 19, pp. 1696-1705, ISSN:1535-3907 DOI

McCartney A.; Vignoli A.; Tenori L.; Fornier M.; Rossi L.; Risi E.; Luchinat C.; Biganzoli L.; Di Leo A. (2019). Metabolomic analysis of serum may refine 21-gene expression assay risk recurrence stratification. NPJ BREAST CANCER, vol. 5, pp. 26-31, ISSN:2374-4677 DOI Accesso ONLINE all'editore

Vignoli, Alessia; Ghini, Veronica; Meoni, Gaia; Licari, Cristina; Takis, Panteleimon G; Tenori, Leonardo; Turano, Paola; Luchinat, Claudio (2019). High-throughput metabolomics by 1D NMR. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 58, pp. 968-994, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Vignoli, Alessia; Orlandini, Beatrice; Tenori, Leonardo; Biagini, Maria Rosa; Milani, Stefano; Renzi, Daniela; Luchinat, Claudio; Calabrò, Antonino Salvatore (2019). Metabolic Signature of Primary Biliary Cholangitis and Its Comparison with Celiac Disease. JOURNAL OF PROTEOME RESEARCH, vol. 18, pp. 1228-1236, ISSN:1535-3907 DOI Accesso ONLINE all'editore

Vignoli, Alessia; Tenori, Leonardo; Giusti, Betti; Takis, Panteleimon G; Valente, Serafina; Carrabba, Nazario; Balzi, Daniela; Barchielli, Alessandro; Marchionni, Niccolò; Gensini, Gian Franco; Marcucci, Rossella; Luchinat, Claudio; Gori, Anna Maria (2019). NMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort. BMC MEDICINE, vol. 17, pp. 0-0, ISSN:1741-7015 DOI Accesso ONLINE all'editore

Rittweger, Jörn; Albracht, Kirsten; Flück, Martin; Ruoss, Severin; Brocca, Lorenza; Longa, Emanuela; Moriggi, Manuela; Seynnes, Olivier; Di Giulio, Irene; Tenori, Leonardo; Vignoli, Alessia; Capri, Miriam; Gelfi, Cecilia; Luchinat, Claudio; Francheschi, Claudio; Bottinelli, Roberto; Cerretelli, Paolo; Narici, Marco (2018). Sarcolab pilot study into skeletal muscle’s adaptation to long-term spaceflight. NPJ MICROGRAVITY, vol. 4, pp. 0-0, ISSN:2373-8065 DOI

McCartney, Amelia; Vignoli, Alessia; Biganzoli, Laura; Love, Richard; Tenori, Leonardo; Luchinat, Claudio; Di Leo, Angelo* (2018). Metabolomics in breast cancer: A decade in review. CANCER TREATMENT REVIEWS, vol. 67, pp. 88-96, ISSN:0305-7372 DOI Accesso ONLINE all'editore

Montuschi, Paolo*; Santini, Giuseppe; Mores, Nadia; Vignoli, Alessia; Macagno, Francesco; Shoreh, Rugia; Tenori, Leonardo; Zini, Gina; Fuso, Leonello; Mondino, Chiara; Di Natale, Corrado; D'Amico, Arnaldo; Luchinat, Claudio; Barnes, Peter J.; Higenbottam, Tim (2018). Breathomics for assessing the effects of treatment and withdrawal with inhaled beclomethasone/formoterol in patients with COPD. FRONTIERS IN PHARMACOLOGY, vol. 9, pp. 258-272, ISSN:1663-9812 DOI Accesso ONLINE all'editore

Tenori, L.; Giusti, B.; Vignoli, A.; Gori, A.M.; Luchinat, C.; Grifoni, E.; Barchielli, A.; Balzi, D.; Marchionni, N.; Marcucci, R. (2017). Metabolomics by Nuclear Magnetic Resonance identifies patients with high risk of death within two years after a cardiovascular event: The case of the amiflorence II study. NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, vol. 27, pp. e39-e40, ISSN:0939-4753 DOI

Hart, Christopher D; Vignoli, Alessia; Tenori, Leonardo; Uy, Gemma Leonora; To, Ta Van; Adebamowo, Clement; Hossain, Syed Mozammel; Biganzoli, Laura; Risi, Emanuela; Love, Richard R; Luchinat, Claudio; Di Leo, Angelo (2017). Serum Metabolomic Profiles Identify ER-Positive Early Breast Cancer Patients at Increased Risk of Disease Recurrence in a Multicenter Population. CLINICAL CANCER RESEARCH, vol. 23, pp. 1422-1431, ISSN:1078-0432 DOI

Mccartney, Amelia; Vignoli, Alessia; Hart, Christopher; Tenori, Leonardo; Luchinat, Claudio; Biganzoli, Laura; Di Leo, Angelo (2017). De-escalating and escalating treatment beyond endocrine therapy in patients with luminal breast cancer. THE BREAST, vol. In press, pp. 0-0, ISSN:0960-9776 DOI Accesso ONLINE all'editore

Vignoli, Alessia (2017). Applications of metabolomics in biomedicine. (Tutor: Claudio Luchiant)

Vignoli, Alessia; Tenori, Leonardo; Luchinat, Claudio; Saccenti, Edoardo (2017). Age and Sex Effects on Plasma Metabolite Association Networks in Healthy Subjects. JOURNAL OF PROTEOME RESEARCH, pp. 97-107, ISSN:1535-3893 DOI

Grifoni, E; Vignoli, A; Tenori, L; Giusti, B; Takis, PG; Valente, S; Carrabba, N; Balzi, D; Barchielli, AM; Marchionni, N; Gensini, GF; Marcucci, R; Luchinat, C; Gori, AM (2017). Metabolomics by nuclear magnetic resonance identifies patients at high risk of death within two years after acute coronary syndrome. EUROPEAN HEART JOURNAL, vol. 38, pp. 786-786, ISSN:0195-668X

Basoglu, Abdullah; Baspinar, Nuri; Tenori, Leonardo; Vignoli, Alessia; Gulersoy, Erdem (2017). Effects of Boron Supplementation on Peripartum Dairy Cows’ Health. BIOLOGICAL TRACE ELEMENT RESEARCH, pp. 1-8, ISSN:0163-4984 DOI Accesso ONLINE all'editore

Basoglu, Abdullah; Baspinar, Nuri; Tenori, Leonardo; Vignoli, Alessia; Yildiz, Ramazan (2016). Plasma metabolomics in calves with acute bronchopneumonia. METABOLOMICS, vol. 12, pp. 128-138, ISSN:1573-3882 DOI Accesso ONLINE all'editore

Hart, Cd; Vignoli, Alessia; Tenori, Leonardo; Biganzoli, L; Risi, Emanuela; Love, Rr; Luchinat, Claudio; Di Leo, A. (2016). Serum metabolomic profiles identify ER-positive early breast cancer patients at increased risk of disease recurrence in a multicentre population. ANNALS OF ONCOLOGY, vol. 27, pp. 152PD-0, ISSN:0923-7534 DOI

DI DONATO, Samantha; Mislang, A. R.; Vignoli, Alessia; Mori, Elena; Vitale, Sergio; Biagioni, Chiara; Hart, C.; Becheri, Dimitri; DEL MONTE, Francesca; Luchinat, Claudio; Di Leo, A.; Mottino, G.; Tenori, Leonardo; Biganzoli, L. (2016). D20Serum metabolomic as biomarkers to differentiate early from metastatic disease in elderly colorectal cancer (crc) patients. ANNALS OF ONCOLOGY, vol. 27, pp. iv45-iv45, ISSN:0923-7534 DOI

Mislang, Anna Rachelle; Vignoli, Alessia; Donato, Samantha Di; Hart, Christopher; Biagioni, Chiara; Vitale, Stefania; Mori, Elena; Becheri, Dimitri; Monte, Francesca Del; Luchinat, Claudio; Leo, Angelo Di; Mottino, Giuseppe; Tenori, Leonardo; Biganzoli, Laura (2016). Serum metabolomics as biomarkers to differentiate early from metastatic disease and predict relapse in elderly colorectal cancer (CRC) patients.. JOURNAL OF CLINICAL ONCOLOGY, pp. 0-0, ISSN:1527-7755 DOI

Christopher, Hart D; Vignoli, Alessia; Tenori, Leonardo; Risi, Emanuela; Love, Richard R; Luchinat, Claudio (2016). A RISK SCORE BASED ON PREOPERATIVE SERUM METABOLOMIC PROFILES IDENTIFIES PATIENTS WITH EARLY BREAST CANCER AT INCREASED RISK OF RECURRENCE IN A MULTICENTER POPULATION: OUTCOMES BY ADJUVANT ONLINE STRATIFICATION. ASIA PACIFIC JOURNAL OF CLINICAL ONCOLOGY, vol. 12, pp. 104-168, ISSN:1743-7555 DOI

Santini, Giuseppe; Mores, Nadia; Luchinat, Claudio; Tenori, Leonardo; Vignoli, Alessia; Macagno, Francesco; Fuso, Leonello; Higenbottam, Tim; Montuschi, Paolo (2016). Effects of treatment and withdrawal with inhaled beclomethasone/formoterol on electronic nose and NMR metabolomic breathprints in patients with COPD. EUROPEAN RESPIRATORY JOURNAL, pp. PA1075-PA1075, ISSN:1399-3003 DOI

Vignoli, Alessia; Rodio, Donatella Maria; Bellizzi, Anna; Sobolev, Anatoly Petrovich; Anzivino, Elena; Mischitelli, Monica; Tenori, Leonardo; Marini, Federico; Priori, Roberta; Scrivo, Rossana; Valesini, Guido; Francia, Ada; Morreale, Manuela; Ciardi, Maria Rosa; Iannetta, Marco; Campanella, Cristiana; Capitani, Donatella; Luchinat, Claudio; Pietropaolo, Valeria; Mannina, Luisa (2016). NMR-based metabolomic approach to study urine samples of chronic inflammatory rheumatic disease patients. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, pp. 1-9, ISSN:1618-2642 DOI Accesso ONLINE all'editore

Alessia VIGNOLI

Biography

Alessia Vignoli graduated with a M.Sc. in Chemical Sciences cum laude (curriculum: Chemistry of Biological Molecules) at the University of Florence in 2014. The same year she won a PhD scholarship for the International Doctorate in Structural Biology at the same University, and she obtained her PhD cum laude in 2017.
She has been post-doctoral researcher (2018) under the supervision of Prof. Luchinat at CERM/CIRMMP and recipient of an AIRC fellowship (2019-2020) for her project "METabolomic profile as a prognostic biomarker of risk of recurrence in patients operated for COLon cancer (METCOL)". Under the guidance of Prof. Leonardo Tenori, she has been post-doctoral fellow (2021-2022) at the Chemistry Department of the University of Florence. In 2023 she joined the faculty at the same Department as fixed-term researcher.

Alessia VIGNOLI

Curriculum

Education and Training

Scientific High School Diploma (P.N.I.) – 2007
Bachelor’s Degree in Chemistry (Class–21) – University of Florence – 2011, thesis: "Synthesis of gliadin and tissue transglutaminase peptides for the study of the antibody response in celiac disease," Supervisor: Prof. Anna Maria Papini.
M.Sc. in Chemical Sciences (LM-54) – University of Florence – 2014, thesis: "Applications of Metabolomics in Biomedicine: a longitudinal prospective study on patients with Chronic Obstructive Pulmonary Disease (COPD)," Supervisor: Prof. Claudio Luchinat.
International Doctorate in Structural Biology – University of Florence – 2017, thesis: "Applications of Metabolomics in Biomedicine," Supervisor: Prof. Claudio Luchinat.
24-CFU Training Program in Anthropo-Psycho-Pedagogical Disciplines and Teaching Methodologies and Technologies – University of Florence – 2018

Work experience

Fixed-term Researcher (RTD-A), SDG 03/CHEM-03, SSD CHEM-03/A – Department of Chemistry “Ugo Schiff,” University of Florence – Since February 2023
Post-Doctoral Research Fellow – Department of Chemistry “Ugo Schiff,” University of Florence – Scientific Supervisor: Dr. Leonardo Tenori, Scientific Research (SSD CHEM-03/A) – 2021-2023
Post-Doctoral Fellow – AIRC Foundation for Cancer Research – Interuniversity Consortium on Magnetic Resonance of Metalloproteins (CIRMMP) – Scientific Supervisor: Prof. Claudio Luchinat – 2019-2020
Post-Doctoral Researcher – Interuniversity Consortium on Magnetic Resonance of Metalloproteins (CIRMMP) – Scientific Supervisor: Prof. Claudio Luchinat – 2017-2018
Pre-Doctoral Fellow – Interuniversity Consortium on Magnetic Resonance of Metalloproteins (CIRMMP) – Scientific Supervisor: Prof. Claudio Luchinat – 2014

Funding and Grants

FIS 2 Starting Grant
Airalzh (Italian Alzheimer’s Research Association) Grant for Young Researchers – AGYR 2022
2-year AIRC Fellowship "Eduardo Spinnato"

Awards and Qualifications

GIDRM Under 35 Award – 2022
National Scientific Qualification as Associate Professor (Second level) in CHEM-03/A General and Inorganic Chemistry – 2022
Best Poster Award (Translational Category), COSA’s 43rd and ANZBCTG’s 38th Annual Scientific Meetings (Gold Coast Convention and Exhibition Centre, Queensland) – 2016

Scientific Output

Scopus ID: 57190191512

ORCID: 0000-0003-4038-6596

Alessia VIGNOLI

Interest

Dr. Vignoli scientific interests are focused on the characterization of the chemical composition of complex matrices such as biofluids by means of nuclear magnetic resonance (NMR) spectroscopy, and on the applications of NMR-based metabolomics in medicine for diagnostic and prognostic purposes.