Ammara, Andrea; Carone, Alessandra; Lucarini, Laura; Sgambellone, Silvia; Marri, Silvia; Villano, Serafina; Matucci, Rosanna; Luga, Gerta; Fittipaldi, Chiara; Pecori, Riccardo; Pieraccini, Giuseppe; Di Serio, Claudia; García-Llorca, Andrea; Eysteinsson, Thor; Kalinin, Stanislav; Viita, Julius Aleksi Olavi; Urtti, Arto; Carta, Fabrizio; Selleri, Silvia; Supuran, Claudiu T (2025). Repurposing Drug Metabolites into Dual β-Adrenergic Receptor-Carbonic Anhydrase Modulators as Potential Tools for Ocular Disorders. JOURNAL OF MEDICINAL CHEMISTRY, pp. 0-0, ISSN:1520-4804 DOI  

  Angeli A.; Chelli I.; Lucarini L.; Sgambellone S.; Marri S.; Villano S.; Ferraroni M.; De Luca V.; Capasso C.; Carta F.; Supuran C.T. (2024). Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy. JOURNAL OF MEDICINAL CHEMISTRY, vol. 67, pp. 3066-3089, ISSN:0022-2623 DOI  

  Kilbile, JT; Sapkal, SB; Renzi, G; D'Agostino, I; Boudjelal, M; Tamboli, Y; Cutarella, L; Mori, M; Sgambellone, S; Villano, S; Marri, S; Lucarini, L; Carradori, S; Carta, F; Supuran, CT (2024). Lasamide Containing Sulfonylpiperazines as Effective Agents for the Management of Glaucoma Associated Symptoms. CHEMMEDCHEM, vol. 19, pp. 0-0, ISSN:1860-7179 DOI  

  Sgambellone, Silvia; Marri, Silvia; Villano, Serafina; Masini, Emanuela; Provensi, Gustavo; Bastia, Elena; Galli, Corinna; Brambilla, Stefania; Impagnatiello, Francesco; Lucarini, Laura (2023). NCX 470 Exerts Retinal Cell Protection and Enhances Ophthalmic Artery Blood Flow After Ischemia/Reperfusion Injury of Optic Nerve Head and Retina. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, vol. 12, pp. 1-11, ISSN:2164-2591 DOI  

  Sgambellone Silvia (2023). Histamine H3 receptor (H3R) antagonist-Nitric Oxide (NO) donor hybrid compounds as a new therapeutic strategy for the treatment of glaucoma and retinal neuroprotection. (Tutor: Carla Ghelardini, Maria Beatrice Passani)

  Sgambellone, Silvia; Marri, Silvia; Catarinicchia, Stefano; Pini, Alessandro; Tosh, Dilip K.; Jacobson, Kenneth A.; Masini, Emanuela; Salvemini, Daniela; Lucarini, Laura (2022). Adenosine A3 Receptor (A3AR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 0-0, ISSN:1422-0067 DOI  

  Chiaramonte N.; Angeli A.; Sgambellone S.; Bonardi A.; Nocentini A.; Bartolucci G.; Braconi L.; Dei S.; Lucarini L.; Teodori E.; Gratteri P.; Wunsch B.; Supuran C.T.; Romanelli M.N. (2022). 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 228, pp. 0-0, ISSN:0223-5234 DOI  

  Rosa, Arianna Carolina; Nardini, Patrizia; Sgambellone, Silvia; Gurrieri, Maura; Spampinato, Simona Federica; Dell'Accio, Alfonso; Chazot, Paul L; Obara, Ilona; Liu, Wai L; Pini, Alessandro (2022). CNS-Sparing Histamine H3 Receptor Antagonist as a Candidate to Prevent the Diabetes-Associated Gastrointestinal Symptoms. BIOMOLECULES, vol. 12, pp. 184-196, ISSN:2218-273X DOI  

  Elena Bastia; Silvia Sgambellone; Laura Lucarini; Gustavo Provensi; Stefania Brambilla; Corinna Galli; Nicoletta Almirante; Francesco Impagnatiello (2022). NCX 470 Restores Ocular Hemodynamics and Retinal Cell Physiology After ET-1-Induced Ischemia/Reperfusion Injury of Optic Nerve and Retina in Rabbits. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, vol. 38, pp. 496-504, ISSN:1557-7732 DOI  

  Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino, Debora Collotta, Gustavo Provensi, Emanuela Masini, Massimo Collino (2021). D-Tagatose Feeding Reduces the Risk of Sugar-Induced Exacerbation of Myocardial I/R Injury When Compared to Its Isomer Fructose. FRONTIERS IN MOLECULAR BIOSCIENCES, vol. 8, pp. 1-12, ISSN:2296-889X DOI  

  Vannozzi G.; Vullo D.; Angeli A.; Ferraroni M.; Combs J.; Lomelino C.; Andring J.; Mckenna R.; Bartolucci G.; Pallecchi M.; Lucarini L.; Sgambellone S.; Masini E.; Carta F.; Supuran C.T. (2021). One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes. JOURNAL OF MEDICINAL CHEMISTRY, vol. 65, pp. 824-837, ISSN:0022-2623 DOI  

  Micheli L.; Durante M.; Lucarini E.; Sgambellone S.; Lucarini L.; Di Cesare Mannelli L.; Ghelardini C.; Masini E. (2021). The histamine h4 receptor participates in the anti-neuropathic effect of the adenosine a3 receptor agonist ib-meca: Role of cd4+ t cells. BIOMOLECULES, vol. 11, pp. 1447-1447, ISSN:2218-273X DOI  

  Lucarini L.; Durante M.; Sgambellone S.; Lanzi C.; Bigagli E.; Akgul O.; Masini E.; Supuran C.T.; Carta F. (2020). Effects of new nsaid-cai hybrid compounds in inflammation and lung fibrosis. BIOMOLECULES, vol. 10, pp. 1-20, ISSN:2218-273X DOI  

  Bonardi A.; Nocentini A.; Bua S.; Combs J.; Lomelino C.; Andring J.; Lucarini L.; Sgambellone S.; Masini E.; McKenna R.; Gratteri P.; Supuran C.T. (2020). Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action. JOURNAL OF MEDICINAL CHEMISTRY, vol. 63, pp. 7422-7444, ISSN:0022-2623 DOI  

  Lanzi C.; Lucarini L.; Durante M.; Sgambellone S.; Pini A.; Catarinicchia S.; Lazewska D.; Kiec-Kononowicz K.; Stark H.; Masini E. (2019). Role of histamine H3 receptor antagonists on intraocular pressure reduction in rabbit models of transient ocular hypertension and glaucoma. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, pp. 981-995, ISSN:1661-6596 DOI   Accesso ONLINE all'editore

  Durante M.; Sgambellone S.; Lanzi C.; Nardini P.; Pini A.; Moroni F.; Masini E.; Lucarini L. (2019). Effects of PARP-1 deficiency and histamine H4receptor inhibition in an inflammatory model of lung fibrosis in mice. FRONTIERS IN PHARMACOLOGY, vol. 10, pp. 1-13, ISSN:1663-9812 DOI   Accesso ONLINE all'editore

  Spadoni, Gilberto; Bedini, Annalida; Furiassi, Lucia; Mari, Michele; Mor, Marco; Scalvini, Laura; Lodola, Alessio; Ghidini, Andrea; Lucini, Valeria; Dugnani, Silvana; Scaglione, Francesco; Piomelli, Daniele; Jung, Kwang-Mook; Supuran, Claudiu T; Lucarini, Laura; Durante, Mariaconcetta; Sgambellone, Silvia; Masini, Emanuela; Rivara, Silvia (2018). Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit. JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, pp. 0-0, ISSN:0022-2623 DOI  

  Nocentini, Alessio; Ceruso, Mariangela; Bua, Silvia; Lomelino, Carrie L.; Andring, Jacob T.; McKenna, Robert; Lanzi, Cecilia; Sgambellone, Silvia; Pecori, Riccardo; Matucci, Rosanna; Filippi, Luca; Gratteri, Paola; Carta, Fabrizio; Masini, Emanuela; Selleri, Silvia*; Supuran, Claudiu T. (2018). Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy. JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, pp. 5380-5394, ISSN:0022-2623 DOI   Accesso ONLINE all'editore