Alessandro DELLA PUPPA

Ruolo attuale:: Professore Ordinario
SSD:: MEDS-15/A - Neurochirurgia
Afferenza organizzativa:: Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)

Recapiti

alessandro.dellapuppa(AT)unifi.it

Ulteriori Recapiti

SOD Neurochirurgia, IV piano padiglione 25 (ex CTO), AOU Careggi, Largo Brambilla Firenze

Alessandro DELLA PUPPA

Orario di ricevimento (aggiornato al 05/05/2019)

Su appuntamento

alessandro.dellapuppa@unifi.it

Alessandro DELLA PUPPA

Biografia

Nato a Venezia, centro storico, il 28 aprile 1967.

Laureato a pieni voti in Medicina e Chirurgia presso l’Università degli Studi di Padova nel 1992. Ha frequentato la Scuola di Sanità Militare di Firenze svolgendo poi il servizio militare come Ufficiale medico presso il Policlinico Militare di Padova (1994-1995). Ha frequentato la Scuola di Specializzazione in Neurochirurgia presso l’Università degli Studi di Padova dal 1995, ottenendo il Diploma nel 2000.

Ha successivamente lavorato quale Dirigente Medico Ospedaliero di I Livello presso l’Unità Operativa Complessa di Neurochirurgia dell’Azienda Ospedaliera Universitaria di Padova (Direttore Dott Renato Scienza) per quasi 20 anni. Dal 2014 ha ricoperto il ruolo di sostituto del Direttore. Nel febbraio 2018 è stato nominato Direttore della Neurochirurgia di Padova.

Ha successivamente partecipato e vinto il Concorso per Professore Associato di Neurochirurgia (MED/27) dell’Università degli studi di Firenze, prendendo servizio il 1 Dicembre 2018. Dalla stessa data assumeva in ambito assistenziale la Direzione della Neurochirurgia (Struttura Ospedaliera Dipartimentale Complessa a Direzione Universitaria) presso l’Azienda Universitaria Ospedaliera di Careggi,

Dal novembre 2019 Direttore della Scuola di Specializzazione in Neurochirurgia dell’Università degli studi di Firenze.

Dal 2023 Professore Ordinario dell’Università degli studi di Firenze

E' autore/coautore di oltre 200 pubblicazioni su riviste internazionali indicizzate. Oltre 200 relazioni a Convegni

Co-Presidente di 2 Congressi Nazionali. Direttore/Responsabile di circa 31 Convegni accreditati ECM. Direttore/Responsabile/Docente di 28 Corsi di Live Surgery

Nella sua casistica operatoria risulta primo operatore in circa 2700 craniotomie di cui circa 2400 in chirurgia maggiore elettiva (oncologica, vacolare, basicranio). Particolare competenza nell’applicazione intra-operatoria di tecnologie innovative

Alessandro DELLA PUPPA

Curriculum

STUDI

(1981-1986) Liceo scientifico “G.B.Benedetti”,Venezia

(1987-1992) Facoltà di Medicina e Chirurgia Università degli Studi di Padova

(1994-1995) Scuola di Sanità Militare Firenze

(1995-2000) Scuola di Specializzazione in Neurochirurgia,Università degli Studi di Padova

FORMAZIONE ACCADEMICA

(2017-2018) Professore a Contratto, Dipartimento di Neuroscienze, Università degli studi di Padova

(2018-oggi) Professore Associato di Neurochirurgia (MED/27), Dipartimento NEUROFARBA, Università degli studi di Firenze

FORMAZIONE ASSISTENZIALE

(1991-1992) Allievo Interno, Clinica Neurologica I, Azienda Ospedaliera Universitaria di Padova

(1992-1993) Medico Frequentatore, Unità di Neuroradiologia, Azienda Ospedaliera di Padova

(1994) Medico Frequentatore, Unità di Neurotraumatologia, Azienda Ospedaliera Universitaria di Padova

(1994-1995) Ufficiale Medico (Ospedale Militare di Padova)

(1995-2000) Specializzando in Neurochirurgia, Università di Padova

(2002-2008) Dirigente Medico I livello a tempo determinato, Unità Complessa di di Neurochirurgia, AOU Padova

(2008-2018) Dirigente Medico I livello a tempo indeterminato, Unità Complessa di di Neurochirurgia, AOU Padova

(2014-2018) Sostituto del Direttore Unità Complessa di di Neurochirurgia, AOU Padova

(feb -nov 2018 ) Direttore Unità Complessa di di Neurochirurgia, AOU Padova

(dic 2018-oggi) Direttore SOD Complessa Neurochirurgia 2, AOU Careggi, Firenze

(mar 2019-oggi) Direttore ad Interim SOD Complessa Neurochirurgia 1, AOU Careggi, Firenze

FORMAZIONE MANAGERIALE

(2009) Corso di Economia Sanitaria. Università degli studi di Padova

(2014) Corso di Management Sanitario, Università SDA Bocconi, , School of Management Milano “Management dell’Ospedale”

(2015) Corso di Management Sanitario, Università SDA Bocconi, School of Management, Milano “ Il Medico che governa l’organizzazione”

ESPERIENZE CLINICHE ALL’ESTERO (SOGGIORNI DI STUDIO e CORSI DI AGGIORNAMENTO ALL’ESTERO)

(2007) Dipartimento di Neurochirurgia, Johns Hopkins School of Medicine, Baltimora-Maryland (U.S.A.)

(2009) Dipartimento di Neurochirurgia, Ospedale Universitario di Montpellier (Francia)

(2010) Dipartimento di Neurochirurgia, Ospedale Universitario di Montpellier (Francia)

(2011) Dipartimento di Neurochirurgia di Graz (Austria)

(2011) Dipartimenti di Neuro-Oncologia e di Neurochirurgia del Gruppo Ospedaliero “Pitie-Salpetriere di Parigi (Francia)

(2012) Dipartimento di Neurochirurgia, Ospedale Universitario di Helsinki (Finlandia)

(2013) Dipartimento di Neurochirurgia, Muenster, Germania

(2013) Dipartimento di Neurochirurgia di Lugano (Bellinzona) (Svizzera)

(2013) Dipartimento di Neurochirurgia, Ospedale Universitario di Helsinki(Finlandia)

LAUREA, DIPLOMI, ABILITAZIONI, PATENTI, ASSOCIAZIONI

LAUREA

.Laurea in Medicina e Chirurgia, Novembre 1992, Università degli Studi di Padova

DIPLOMA DI SPECIALIZZAZIONE

.Diploma di Specializzazione in Neurochirurgia, Aprile 2000, Università degli Studi di Padova

ABILITAZIONI

.Abilitazione all’esercizio della professione medica, Novembre 1992, Università degli Studi di Padova

.Abilitazione Scientifica Nazionale (bando 2012) a funzioni di seconda fascia Settore 06/E3 (neurochirurgia e chirurgia maxillo-facciale), 2014

PATENTI

Abilitazione all’uso clinico della fluorescenza con acido 5-aminolevulinico nella chirurgia oncologica (2011)

Abilitazione all’attività formativa sulla chirurgia assistita dalla fluorescenza con acido 5-aminolevulinico (2012)

ASSOCIAZIONI

.Socio ordinario della Società Italiana di Neurochirurgia (SiNch)

.Socio ordinario della Società Italiana di Neuro-Oncologia (AINO)

.Membro della Sezione di Neuro-Oncologia della Società Italiana di Neurochirurgia

.Membro della Sezione di Chirurgia Vascolare della Società Italiana di Neurochirurgia

PREMI, RICONOSCIMENTI

PREMI

Vincitore Borsa di Studio AINR (Associazione Italiana di NeuroRadiologia) 1993

per un periodo di 2 mesi di frequenza presso la Neuroradiologia dell’Ospedale del Children’s Hospital di Philadelphia, USA

(borsa non utilizzata per motivi personali)

RICONOSCIMENTI

Lettera di riconoscimento degli Editori del Journal of Neuro-Oncology per l’attenzione ricevuta dall’articolo

“MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients? Della Puppa A, Persano L, Masi G, Rampazzo E, Sinigaglia A, Pistollato F, Denaro L, Barzon L, Palù G, Basso G, Scienza R, d'Avella D. J Neurooncol. 2012 Jan;106(1):33-41. Epub 2011 Jul 2.”

PUBBLICAZIONI

Contributi in Rivista

Banzato T, Causin F, Della Puppa A, Cester G, Mazzai L, Zotti A. Accuracy of Deep Learning to Differentiate the Histopathological Grading of Meningiomas on MR Images: A Preliminary Study. J Magn Reson Imaging. 2019 Mar 21. doi:10.1002/jmri.26723. [Epub ahead of print] PubMed PMID: 30896065.

Anglani M, Cecchin D, Cester G, Simonato D, Baracchini C, Della Puppa A, Causin F. (18)F-FDG PET-MRI monitoring of brain metabolic changes in a case of AVM related steal phenomenon symptoms.World Neurosurg. 2019 Mar 9. pii: S1878-8750(19)30590-X. doi: 10.1016/j.wneu.2019.02.167. [Epub ahead of print] PubMed PMID: 30862580.

Pinton L, Masetto E, Vettore M, Solito S, Magri S, D'Andolfi M, Del Bianco P, Lollo G, Benoit JP, Okada H, Diaz A, Della Puppa A, Mandruzzato S. The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion. J Immunother Cancer. 2019 Feb 27;7(1):58. doi: 10.1186/s40425-019-0536-x. PubMed PMID: 30813960; PubMed Central PMCID: PMC6391795.

Simonato D, Gabrieli JD, Cester G, Della Puppa A, Causin F. Intracranial stenting after tumor exeresis complicated by delayed kinking of the middle cerebral artery. Acta Neurochir (Wien). 2019 Mar;161(3):593-596. doi: 10.1007/s00701-019-03822-7. Epub 2019 Feb 2. PubMed PMID: 30710240.

Indraccolo S, Lombardi G, Fassan M, Pasqualini L, Giunco S, Marcato R, Gasparini A, Candiotto C, Nalio S, Fiduccia P, Fanelli GN, Pambuku A, Della Puppa A, D'Avella D, Bonaldi L, Gardiman MP, Bertorelle R, De Rossi A, Zagonel V.Genetic, epigenetic and immunologic profiling of MMR-deficient relapsed glioblastoma. Clin Cancer Res. 2018 Dec 4. pii: clincanres.1892.2018. doi:10.1158/1078-0432.CCR-18-1892. [Epub ahead of print] PubMed PMID: 30514778.

Della Puppa A, Munari M, Gardiman MP, Volpin F. Combined fluorescence using 5 aminolevulinic acid (5-ALA) and sodium fluorescein (Fl-Na) at glioblastoma border. Intra-operative findings and histopathological data about 3 newly diagnosed consecutive cases. World Neurosurg. 2018 Nov 1 pii:S1878-8750(18)32461-6. doi: 10.1016/j.wneu.2018.10.163. [Epub ahead of print]PubMed PMID: 30391771.

Pasqualin A, Meneghelli P, Musumeci A, Della Puppa A, Pavesi G, Pinna G, Scienza R. Intraoperative Measurement of Arterial Blood Flow in Aneurysm Surgery.Acta Neurochir Suppl. 2018;129:43-52. doi: 10.1007/978-3-319-73739-3_7. PubMed PMID: 30171313.

Lombardi G, Caccese M, Bellu L, Pambuku A, Bergo E, Berti F, Gardiman MP, Della Puppa A, Denaro L, Dal Pos S, Zagonel V. Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: report of two cases.Anticancer Drugs. 2018 Aug 3. doi: 10.1097/CAD.0000000000000678. [Epub ahead of print] PubMed PMID: 30080691.

Porcù E, Maule F, Boso D, Rampazzo E, Barbieri V, Zuccolotto G, Rosato A,Frasson C, Viola G, Della Puppa A, Basso G, Persano L. BMP9 counteracts the tumorigenic and pro-angiogenic potential of glioblastoma. Cell Death Differ. 2018 Jul 5. doi: 10.1038/s41418-018-0149-9. [Epub ahead of print] PubMed PMID:29977042.

Pinton L, Solito S, Masetto E, Vettore M, Canè S, Della Puppa A, Mandruzzato S.Immunosuppressive activity of tumor-infiltrating myeloid cells in patients with meningioma. Oncoimmunology. 2018 Mar 15;7(7):e1440931. doi:10.1080/2162402X.2018.1440931. eCollection 2018. PubMed PMID: 29900047; PubMed Central PMCID: PMC5993508.

Lombardi G, Della Puppa A, Gardiman MP, Rossi S, Candiotto C, Zanatta L,Bertorelle R, De Rossi A, Fassan M, Zagonel V. Discordance of IDH mutational status between lesions in an adult patient with multifocal glioma. Neuro Oncol. 2018 Jul 5;20(8):1142-1143. doi: 10.1093/neuonc/noy080. PubMed PMID: 29868765.

Milanese L, Martini C, Scaroni C, Dassie F, Ceccato F, Della Puppa A, Denaro L, Bommarito G, Citton V, Ermani M, Maffei P, Manara R. Radiotherapy in acromegaly: Long-term brain parenchymal and vascular magnetic resonance changes. J Neuroradiol. 2018 Mar 2. pii: S0150-9861(17)30296-1. doi:10.1016/j.neurad.2018.02.004. [Epub ahead of print] PubMed PMID: 29505842.

Della Puppa A, Rossetto M, Volpin F, Rustemi O, Grego A, Gerardi A, Ortolan R, Causin F, Munari M, Scienza R. Microsurgical Clipping of Intracranial Aneurysms Assisted by Neurophysiological Monitoring, Microvascular Flow Probe, and ICG-VA: Outcomes and Intraoperative Data on a Multimodal Strategy. World Neurosurg. 2018 May;113:e336-e344. doi: 10.1016/j.wneu.2018.02.029. Epub 2018 Feb 13. PubMed PMID: 29452324.

Rustemi O, Scienza R, Della Puppa A. Tuberculum Sellae Meningioma Resection:Technical Nuances on the Frontopterional Approach. J Neurol Surg B Skull Base.2018 Feb;79(2):S225-S226. doi: 10.1055/s-0037-1620245. Epub 2018 Jan 15. PubMed PMID: 29404262; PubMed Central PMCID: PMC5797317.

Vitale G, Talenti G, Gabrieli J, Cester G, Della Puppa A, Causin F.Endovascular rescue treatment through stent positioning after surgical clipping of intracranial aneurysms complicated by parent artery obstruction. BMJ Case Rep. 2017 Nov 16;2017. pii: bcr-2017-013321. doi: 10.1136/bcr-2017-013321. PubMed PMID: 29146726.

Rampazzo E, Dettin M, Maule F, Scabello A, Calvanese L, D'Auria G, Falcigno L,Porcù E, Zamuner A, Della Puppa A, Boso D, Basso G, Persano L. A synthetic BMP-2 mimicking peptide induces glioblastoma stem cell differentiation. Biochim Biophys Acta. 2017 Sep;1861(9):2282-2292. doi: 10.1016/j.bbagen.2017.07.001. Epub 2017 Jul 4. PubMed PMID: 28687190.

Talenti G, Vitale G, Cester G, Della Puppa A, Faggin R, Causin F. Rare association between spinal dural arteriovenous fistulas and dysraphisms: Report of two cases and review of the literature with a focus on pitfalls in diagnosis and treatment. Interv Neuroradiol. 2017 Jan 1:1591019917714636. doi:10.1177/1591019917714636. [Epub ahead of print] PubMed PMID: 28675347.

Rustemi O, Scienza R, Della Puppa A. Utility of indocyanine green videoangiography in subcortical arteriovenous malformation resection. Neurosurg Focus. 2017 Jul;43(VideoSuppl1):V10. doi: 10.3171/2017.7.FocusVid.1774. PubMed PMID: 28669272.

Rustemi O, Scienza R, Della Puppa A. The unusual subarachnoid hemorrhage presentation by a "sentinel" isolated trochlear nerve palsy of a posterior communicating artery aneurysm. J Neurosurg Sci. 2017 Aug;61(4):444-446. doi:10.23736/S0390-5616.16.03388-9. PubMed PMID: 28555488.

Rustemi O, Scienza R, Della Puppa A. Indocyanine green videoangiography application in distal (M4) middle cerebral artery aneurysm surgery. J Neurosurg Sci. 2017 Jun;61(3):351-354. doi: 10.23736/S0390-5616.16.03271-9. PubMed PMID:28417618.

Arbula S, Pacella V, De Pellegrin S, Rossetto M, Denaro L, D'Avella D, Della Puppa A, Vallesi A. Addressing the selective role of distinct prefrontal areas in response suppression: A study with brain tumor patients. Neuropsychologia. 2017 Jun;100:120-130. doi: 10.1016/j.neuropsychologia.2017.04.018. Epub 2017 Apr 12.PubMed PMID: 28412512.

Lombardi G, Pambuku A, Bellu L, Farina M, Della Puppa A, Denaro L, Zagonel V. Effectiveness of antiangiogenic drugs in glioblastoma patients: A systematic review and meta-analysis of randomized clinical trials. Crit Rev Oncol Hematol. 2017 Mar;111:94-102. doi: 10.1016/j.critrevonc.2017.01.018. Epub 2017 Jan 30. Review. PubMed PMID: 28259301.

Della Puppa A, Rustemi O, Rampazzo E, Persano L. Letter: Combining 5-Aminolevulinic Acid Fluorescence and Intraoperative Magnetic Resonance Imaging in Glioblastoma Surgery: A Histology-Based Evaluation. Neurosurgery. 2017 Feb 1;80(2):E188-E190. doi: 10.1093/neuros/nyw033. PubMed PMID: 28173486.

Griguolo G, Dieci MV, Giarratano T, Giorgi CA, Orvieto E, Ghiotto C, Berti F, Della Puppa A, Falci C, Mioranza E, Tasca G, Milite N, Miglietta F, Scienza R, Conte P, Guarneri V. Beyond breast specific-Graded Prognostic Assessment in patients with brain metastases from breast cancer: treatment impact on outcome. J Neurooncol. 2017 Jan;131(2):369-376. doi: 10.1007/s11060-016-2309-4. Epub 2016 Nov 16. PubMed PMID: 27853958.

Della Puppa A, Lombardi G, Rossetto M, Rustemi O, Berti F, Cecchin D, Gardiman MP, Rolma G, Persano L, Zagonel V, Scienza R. Outcome of patients affected by newly diagnosed glioblastoma undergoing surgery assisted by 5-aminolevulinic acid guided resection followed by BCNU wafers implantation: a 3-year follow-up. J Neurooncol. 2017 Jan;131(2):331-340. doi:10.1007/s11060-016-2301-z. Epub 2016 Oct 18. PubMed PMID: 27757721.

Della Puppa A, Rustemi O, Scienza R. The "ICG Entrapment Sign" in Cerebral Aneurysm Surgery Assisted by Indocyanine Green Videoangiography. World Neurosurg. 2017 Jan;97:287-291. doi: 10.1016/j.wneu.2016.10.011. Epub 2016 Oct 12. PubMed PMID: 27744080.

Rustemi O, Gardiman MP, Scienza R, Della Puppa A. 5-ALA fluorescence applied to glioneuronal tumors. Acta Neurochir (Wien). 2016 Nov;158(11):2123-2125. Epub 2016 Sep 27. PubMed PMID: 27677523.

Semenza C, Salillas E, De Pallegrin S, Della Puppa A. Balancing the 2 Hemispheres in Simple Calculation: Evidence From Direct Cortical Electrostimulation. Cereb Cortex. 2016 Sep 24. [Epub ahead of print] PubMed PMID:27664964.

Della Puppa A, Scienza R. Multimodal Flow-Assisted Resection of Brain AVMs. Acta Neurochir Suppl. 2016;123:141-5. doi: 10.1007/978-3-319-29887-0_20. PubMed PMID: 27637641.

Lombardi G, Della Puppa A, Zagonel V. Urine 2-Hydroxyglutarate in Glioma. 2016 Aug;21(8):1026. doi: 10.1634/theoncologist.2016-0123. PubMed PMID: 27507897; PubMed Central PMCID: PMC4978559.

Bergo E, Lombardi G, Pambuku A, Della Puppa A, Bellu L, D'Avella D, Zagonel V. Cognitive Rehabilitation in Patients with Gliomas and Other Brain Tumors: State of the Art. Biomed Res Int. 2016;2016:3041824. doi: 10.1155/2016/3041824. Epub 2016 Jul 14. Review. PubMed PMID: 27493954; PubMed Central PMCID: PMC4963561.

Maule F, Bresolin S, Rampazzo E, Boso D, Della Puppa A, Esposito G, Porcù E, Mitola S, Lombardi G, Accordi B, Tumino M, Basso G, Persano L. Annexin 2° sustains glioblastoma cell dissemination and proliferation. 2016 Aug 23;7(34):54632-54649. doi: 10.18632/oncotarget.10565. PubMed PMID: 27429043; PubMed Central PMCID: PMC5342369.

Lombardi G, Bellu L, Pambuku A, Della Puppa A, Fiduccia P, Farina M, D'Avella D, Zagonel V. Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study. J Neurooncol. 2016 Jul;128(3):481-6. doi: 10.1007/s11060-016-2136-7. Epub 2016 May 11. PubMed PMID: 27165580.

Rustemi O, Cester G, Causin F, Scienza R, Della Puppa A. Indocyanine Green Videoangiography Transoptic Visualization and Clipping Confirmation of an Optic Splitting Ophthalmic Artery Aneurysm. World Neurosurg. 2016 Jun;90:705.e5-705.e8. doi: 10.1016/j.wneu.2016.03.010. Epub 2016 Mar 12. PubMed PMID: 26979923.

Della Puppa A, Rustemi O, Scienza R. Intraoperative Flow Measurement by Microflow Probe During Spinal Dural Arteriovenous Fistula Surgery. World Neurosurg. 2016 May;89:413-9. doi: 10.1016/j.wneu.2016.02.043. Epub 2016 Feb 17. PubMed PMID: 26898487.

Rustemi O, Scienza R, Della Puppa A.Intra-operative devascularization of petroclival meningiomas by ICG-VA-guided Bernasconi & Cassinari artery identification.Acta Neurochir (Wien). 2016 Mar;158(3):427-8. doi: 10.1007/s00701-016-2704-9. Epub 2016 Jan 19. PubMed PMID: 26782829.

Rustemi O, Scienza R, Della Puppa A. ICG-VA application in subtemporal transtentorial treatment of a Cognard V dural arteriovenous fistula. Neurosurg Focus. 2016 Jan;40 Video Suppl 1:2016.1.FocusVid.15423. doi:10.3171/2016.1. FocusVid.15423. PubMed PMID: 26722687.

Ferroni L, Gardin C, Della Puppa A, Sivolella S, Brunello G, Scienza R, Bressan E, D'Avella D, Zavan B. Novel Nanotechnologies for Brain Cancer Therapeutics and Imaging. J Biomed Nanotechnol. 2015 Nov;11(11):1899-912. Review. PubMed PMID: 26554151.

Lombardi G, Pace A, Pasqualetti F, Rizzato S, Faedi M, Anghileri E, Nicolotto E, Bazzoli E, Bellu L, Villani V, Fabi A, Ferrazza P, Gurrieri L, Dall'Agata M, Eoli M, Della Puppa A, Pambuku A, D'Avella D, Berti F, Rudà R, Zagonel V. Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy)irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology). J Neurooncol. 2015 Nov;125(2):359-67. doi: 10.1007/s11060-015-1923-x. Epub 2015 Sep 30. PubMed PMID: 26423801.

Cagnin A, Simioni M, Tagliapietra M, Citton V, Pompanin S, Della Puppa A, Ermani M, Manara R. A Simplified Callosal Angle Measure Best Differentiates Idiopathic-Normal Pressure Hydrocephalus from Neurodegenerative Dementia. J Alzheimers Dis. 2015;46(4):1033-8. doi: 10.3233/JAD-150107. PubMed PMID:26402630.

Rossetto M, Ciccarino P, Lombardi G, Rolma G, Cecchin D, Della Puppa A. Surgery on motor area metastasis.Neurosurg Rev. 2016 Jan;39(1):71-7; discussion 77-8. doi: 10.1007/s10143-015-0648-9. Epub 2015 Jul 17. PubMed PMID: 26178239.

Marin D, Pitteri M, Della Puppa A, Meneghello F, Biasutti E, Priftis K, Vallesi A. Mental time line distortion in right-brain-damaged patients: Evidence from a dynamic spatiotemporal task. Neuropsychology. 2016 Mar;30(3):338-45. doi: 10.1037/neu0000211. Epub 2015 May 25. PubMed PMID: 26011115.

Della Puppa A, De Pellegrin S, Merola F, Rolma G, Vallesi A. Functional MRI and calculation processing: considerations on preliminary experience about intra-operative validation by electro-stimulation. Neurol Sci. 2015 Sep;36(9):1729-31. doi: 10.1007/s10072-015-2255-5. Epub 2015 May 17. PubMed PMID:25981232.

Della Puppa A, d'Avella E, Rossetto M, Volpin F, Rustemi O, Gioffrè G, Lombardi G, Rolma G, Scienza R. Open Transcranial Resection of Small (<35 mm) Meningiomas of the Anterior Midline Skull Base in Current Microsurgical Practice. World Neurosurg. 2015 Sep;84(3):741-50. doi: 10.1016/j.wneu.2015.04.055. Epub 2015 May 7. PubMed PMID: 25957724.

Della Puppa A, Rustemi O, Scienza R. The suboccipital midline approach to foramen magnum meningiomas: safety and efficacy in a series of 23 consecutive patients over a 5-year period. Acta Neurochir (Wien). 2015 Jul;157(7):1275-6. doi: 10.1007/s00701-015-2438-0. Epub 2015 May 7. PubMed PMID: 25948080.

Della Puppa A, De Pellegrin S, Rossetto M, Rustemi O, Saladini M, Munari M, Scienza R. Intraoperative functional mapping of calculation in parietal surgery. New insights and clinical implications. Acta Neurochir (Wien). 2015 Jun;157(6):971-7; discussion 977. doi: 10.1007/s00701-015-2426-4. Epub 2015 Apr 30. PubMed PMID: 25921855.

Ferroni L, Della Puppa A, D'Avella D, Isola M, Scienza R, Gardin C, Zavan B. Tissue Engineering Strategies as Tools for Personalized Meningioma Treatment. Artif Organs. 2015 Jul;39(7):E114-26. doi: 10.1111/aor.12483. Epub 2015 Apr 20.PubMed PMID: 25894852.

Lombardi G, Corona G, Bellu L, Della Puppa A, Pambuku A, Fiduccia P, Bertorelle R, Gardiman MP, D'Avella D, Toffoli G, Zagonel V.Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma. Oncologist. 2015 May;20(5):562-7. doi: 10.1634/theoncologist.2014-0266. Epub 2015 Apr 10. PubMed PMID: 25862748; PubMed Central PMCID: PMC4425377.

Della Puppa A, Rustemi O, Scienza R. Intraoperative flow measurement by microflow probe during surgery for brain arteriovenous malformations. Neurosurgery. 2015 Jun;11 Suppl 2:268-73. doi: 0.1227/NEU.0000000000000741.PubMed PMID: 25812071.

Della Puppa A, Rustemi O, Scienza R. The suboccipital midline approach to foramen magnum meningiomas.Acta Neurochir (Wien). 2015 May;157(5):869-73. doi: 10.1007/s00701-015-2381-0. Epub 2015 Mar 17. PubMed PMID: 25772346.

Della Puppa A, Rustemi O, Scienza R. Letter to the editor: quality of life of patients affected by unruptured brain AVMs. J Neurosurg. 2015 Apr;122(4):984-5. doi: 10.3171/2014.9.JNS141969. Epub 2015 Feb 13. PubMed PMID: 25679275.

Della Puppa A, De Pellegrin S, Lazzarini A, Gioffrè G, Rustemi O, Cagnin A, Scienza R, Semenza C. Subcortical mapping of calculation processing in the right parietal lobe. J Neurosurg. 2015 May;122(5):1038-41. doi: 10.3171/2014.10.JNS14261. Epub 2014 Nov 21. PubMed PMID: 25415072.

Della Puppa A, Rustemi O, Gioffrè G. J Neurosurg. 2014 Sep;121(3):766-8. PubMed PMID: 25317438.

Stummer W, Rodrigues F, Schucht P, Preuss M, Wiewrodt D, Nestler U, Stein M, Artero JM, Platania N, Skjøth-Rasmussen J, Della Puppa A, Caird J, Cortnum S, Eljamel S, Ewald C, González-García L, Martin AJ, Melada A, Peraud A, Brentrup A, Santarius T, Steiner HH; European ALA Pediatric Brain Tumor Study Group.Predicting the "usefulness" of 5-ALA-derived tumor fluorescence for fluorescence-guided resections in pediatric brain tumors: a European survey. Acta Neurochir (Wien). 2014 Dec;156(12):2315-24. doi: 10.1007/s00701-014-2234-2. Epub 2014 Sep 24. PubMed PMID: 25248327; PubMed Central PMCID: PMC4232748.

Lombardi G, Della Puppa A, Di Stefano AL, Pace A, Rudà R, Tabouret E, Zagonel V. Biomed Res Int. 2014;2014:470523. doi: 10.1155/2014/470523. Epub 2014 Aug 26. PubMed PMID: 25243142; PubMed Central PMCID: PMC4160613.

Della Puppa A, Scienza R, Rustemi O, Gioffré G.Can the efficacy of indocyanine green videoangiography in cerebral arterio-venous malformations surgery be further improved? Neurosurgery. 2014 Dec;75(6):E732-4. doi: 10.1227/NEU.0000000000000531. PubMed PMID: 25181438.

Della Puppa A, Rustemi O, Gioffrè G, Scienza R.Approaching a brainstem high-grade glioma (HGG) with the assistance of 5-aminolevulinic acid (5-ALA) technology: a new strategy for an old surgical challenge. Neurol Sci. 2015 May;36(5):797-9. doi: 10.1007/s10072-014-1901-7. Epub 2014 Jul 24. PubMed PMID: 25056195.

Della Puppa A, Rustemi O, Gioffrè G, Causin F, Scienza R. Transdural indocyanine green video-angiography of vascular malformations. Acta Neurochir (Wien). 2014 Sep;156(9):1761-7. doi: 10.1007/s00701-014-2164-z. Epub 2014 Jul 19. PubMed PMID: 25034506.

Sartore L, Venezia ED, Della Puppa A, Bedogni A, Campana L, Giatsidis G. Reconstructive strategies for dermatofibrosarcomas of the face: role of regenerative dermal templates. Head Neck. 2015 Jan;37(1):E8-11. doi: 10.1002/hed.23754. Epub 2014 Jul 21. PubMed PMID: 24816728.

Lombardi G, Della Puppa A, Zustovich F, Pambuku A, Farina P, Fiduccia P, Roma A, Zagonel V. The combination of carmustine wafers and fotemustine in recurrent glioblastoma patients: a monoinstitutional experience. Biomed Res Int. 2014;2014:678191. doi: 10.1155/2014/678191. Epub 2014 Apr 9. PubMed PMID: 24812626; PubMed Central PMCID: PMC4000952.

Della Puppa A, Ciccarino P, Lombardi G, Rolma G, Cecchin D, Rossetto M. 5-Aminolevulinic acid fluorescence in high grade glioma surgery: surgical outcome, intraoperative findings, and fluorescence patterns. Biomed Res Int. 2014;2014:232561. doi: 10.1155/2014/232561. Epub 2014 Apr 8. PubMed PMID:24804203; PubMed Central PMCID: PMC3997860.

Lombardi G, Farina P, Della Puppa A, Cecchin D, Pambuku A, Bellu L, Zagonel V. An overview of fotemustine in high-grade gliomas: from single agent to association with bevacizumab. Biomed Res Int. 2014;2014:698542. doi: 10.1155/2014/698542. Epub 2014 Mar 31. Review. PubMed PMID: 24800248; PubMed Central PMCID: PMC3988896.

Cecchin D, Schiorlin I, Della Puppa A, Lombardi G, Zucchetta P, Bodanza V, Gardiman MP, Rolma G, Frigo AC, Bui F. Assessing response using 99mTc-MIBI early after interstitial chemotherapy with carmustine-loaded polymers in glioblastoma multiforme: preliminary results. Biomed Res Int. 2014;2014:684383. doi: 10.1155/2014/684383. Epub 2014 Mar 27. PubMed PMID: 24800247; PubMed Central PMCID: PMC3985177.

Della Puppa A, De Pellegrin S, Salillas E, Grego A, Lazzarini A, Vallesi A, Saladini M, Semenza C. Functional mapping of left parietal areas involved in simple addition and multiplication. A single-case study of qualitative analysis of errors. J Neuropsychol. 2015 Sep;9(2):330-5. doi: 10.1111/jnp.12043. Epub 2014 Mar 19. PubMed PMID: 24646158.

Della Puppa A, Rustemi O, Rossetto M, Gioffrè G, Munari M, Charbel FT, Scienza R. The "squeezing maneuver" in microsurgical clipping of intracranial aneurysms assisted by indocyanine green videoangiography. 2014 Jun;10 Suppl 2:208-12; discussion 212-3. doi:10.1227/NEU. 0000000000000334. PubMed PMID: 24594928.

Sivolella S, Brunello G, Ferrarese N, Della Puppa A, D'Avella D, Bressan E, Zavan B. Nanostructured guidance for peripheral nerve injuries: a review with a perspective in the oral and maxillofacial area. Int J Mol Sci. 2014 Feb 20;15(2):3088-117. doi: 10.3390/ijms15023088. Review. PubMed PMID: 24562333; PubMed Central PMCID: PMC3958900.

Della Puppa A, Rustemi O, Gioffrè G, Rolma G, Grandis M, Munari M, Scienza R. Application of indocyanine green video angiography in parasagittal meningioma surgery. Neurosurg Focus. 2014 Feb;36(2):E13. doi: 10.3171/2013.12.FOCUS13385. PubMed PMID: 24484251.

Della Puppa A, Rustemi O, Gioffrè G. Is the intra-operative application of indocyanine green effective in retro-orbital surgery? Acta Neurochir (Wien). 2014 Jul;156(7):1419-20. doi: 10.1007/s00701-014-2001-4. Epub 2014 Jan 25. PubMed PMID: 24463742.

Della Puppa A, Rustemi O, Gioffrè G, Troncon I, Lombardi G, Rolma G, Sergi M, Munari M, Cecchin D, Gardiman MP, Scienza R. Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery. J Neurosurg. 2014 Apr;120(4):840-5. doi: 10.3171/2013.12.JNS131642. Epub 2014 Jan 10. PubMed PMID: 24410157.

Rampazzo E, Della Puppa A, Frasson C, Battilana G, Bianco S, Scienza R, Basso G, Persano L. Phenotypic and functional characterization of Glioblastoma cancer stem cells identified through 5-aminolevulinic acid-assisted surgery [corrected]. J Neurooncol. 2014 Feb;116(3):505-13. doi: 10.1007/s11060-013-1348-3. Epub 2014 Jan 9. Erratum in: J Neurooncol. 2014 Oct;120(1):221. PubMed PMID: 24401960.

Della Puppa A, Rustemi O, Gioffre' G. The rare event of optic-chiasmatic hemorrhagic low grade glioma in adulthood. Considerations on treatment strategy.Neurol Sci. 2014 Apr;35(4):623-5. doi: 10.1007/s10072-013-1624-1. Epub 2014 Jan 5. PubMed PMID: 24389919.

Della Puppa A, Rustemi O, Gioffrè G, Leoni L. Brainstem surgery assisted by temporary trans-venous pacing to prevent severe bradycardia.Acta Neurochir (Wien). 2014 Feb;156(2):431-2. doi: 10.1007/s00701-013-1965-9. Epub 2013 Dec 10. PubMed PMID: 24322585.

Della Puppa A, Gioffrè G, Gardiman MP, Frasson C, Cecchin D, Scienza R, Persano L. Intra-operative 5-aminolevulinic acid (ALA)-induced fluorescence of medulloblastoma: phenotypic variability and CD133(+) expression according to different fluorescence patterns.Neurol Sci. 2014 Jan;35(1):99-102. doi: 10.1007/s10072-013-1597-0. Epub 2013 Dec 7. PubMed PMID: 24318560.

Della Puppa A, Volpin F, Gioffre G, Rustemi O, Troncon I, Scienza R. Microsurgical clipping of intracranial aneurysms assisted by green indocyanine videoangiography (ICGV) and ultrasonic perivascular microflow probe measurement.Clin Neurol Neurosurg. 2014 Jan;116:35-40. doi: 10.1016/j.clineuro.2013.11.004. Epub 2013 Nov 18. PubMed PMID: 24309149.

Lombardi G, Pambuku A, Bellu L, Della Puppa A, Rumanò L, Gardiman MP, Pomerri F, Zagonel V. Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma. Chemotherapy. 2013;59(3):176-80. doi: 10.1159/000355662. Epub 2013 Oct 31. PubMed PMID: 24192541.

Rossetto M, Persano L, Scienza R, Della Puppa A.Hydrocephalus after meningioma surgery. Neurosurg Focus. 2013 Nov;35(5):E8. doi: 10.3171/2012.12.FOCUS12214. PubMed PMID: 24175868.

Jelcic N, Della Puppa A, Mottaran R, Cecchin D, Manara R, Dam M, Cagnin A. Case series evidence for improvement of executive functions after late cranioplasty.Brain Inj. 2013;27(13-14):1723-6. doi: 10.3109/02699052.2013.844857. Epub 2013 Oct 10. Review. PubMed PMID: 24111680.

Della Puppa A, Scienza R. 5-Aminolevulinic acid-guided resection of bone-invasive meningiomas.Neurosurg Focus. 2013 Oct;35(4):E6. doi: 10.3171/2012.6.FOCUS12236. PubMed PMID: 24079785.

Manara R, Gabrieli J, Citton V, Ceccato F, Rizzati S, Bommarito G, Briani C, Della Puppa A, Dassie F, Milanese L, Di Salle F, Ermani M, Scaroni C, Martini C, Maffei P. Intracranial internal carotid artery changes in acromegaly: a quantitative magnetic resonance angiography study. 2014 Oct;17(5):414-22. doi: 10.1007/s11102-013-0516-y. PubMed PMID: 24068454.

Lombardi G, Rumiato E, Bertorelle R, Saggioro D, Farina P, Della Puppa A, Zustovich F, Berti F, Sacchetto V, Marcato R, Amadori A, Zagonel V. Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study. Am J Clin Oncol. 2015 Oct;38(5):514-9. doi: 10.1097/COC.0b013e3182a790ea. PubMed PMID:24064758.

Della Puppa A, De Pellegrin S, d'Avella E, Gioffrè G, Munari M, Saladini M, Salillas E, Scienza R, Semenza C. Right parietal cortex and calculation processing: intraoperative functional mapping of multiplication and addition in patients affected by a brain tumor. J Neurosurg. 2013 Nov;119(5):1107-11. doi: 10.3171/2013.6.JNS122445. Epub 2013 Aug 9. PubMed PMID: 23930858.

Sartori MT, Della Puppa A, Ballin A, Campello E, Radu CM, Saggiorato G, d'Avella D, Scienza R, Cella G, Simioni P. Circulating microparticles of glial origin and tissue factor bearing in high-grade glioma: a potential prothrombotic role. Thromb Haemost. 2013 Aug;110(2):378-85. doi: 10.1160/TH12-12-0957. Epub 2013 Jun 27. PubMed PMID: 23803674.

Della Puppa A, d'Avella E, Volpin F, Rustemi O, Gioffre' G, Scienza R. Indocyanine green videoangiography (ICGV) in parasagittal meningiomas surgery. Considerations on veins management and brain function preservation. Acta Neurochir (Wien). 2013 Aug;155(8):1475-6. doi: 10.1007/s00701-013-1784-z. Epub 2013 Jun 4. PubMed PMID: 23732873.

Della Puppa A, De Pellegrin S, d'Avella E, Gioffrè G, Rossetto M, Gerardi A, Lombardi G, Manara R, Munari M, Saladini M, Scienza R.5-aminolevulinic acid (5-ALA) fluorescence guided surgery of high-grade gliomas in eloquent areas assisted by functional mapping. Our experience and review of the literature. Acta Neurochir (Wien). 2013 Jun;155(6):965-72; discussion 972. doi: 10.1007/s00701-013-1660-x. Epub 2013 Mar 7. PubMed PMID: 23468036.

Rampazzo E, Persano L, Pistollato F, Moro E, Frasson C, Porazzi P, Della Puppa A, Bresolin S, Battilana G, Indraccolo S, Te Kronnie G, Argenton F, Tiso N, Basso G. Wnt activation promotes neuronal differentiation of glioblastoma. Cell Death Dis. 2013 Feb 21;4:e500. doi: 10.1038/cddis.2013.32. Erratum in: Cell Death Dis. 2013;4:e597. PubMed PMID: 23429286; PubMed Central PMCID: PMC4098797.

d'Avella E, Volpin F, Manara R, Scienza R, Della Puppa A.Indocyanine green videoangiography (ICGV)-guided surgery of parasagittal meningiomas occluding the superior sagittal sinus (SSS). Acta Neurochir (Wien). 2013 Mar;155(3):415-20. doi: 10.1007/s00701-012-1617-5. Epub 2013 Jan 10. PubMed PMID: 23307335.

Persano L, Pistollato F, Rampazzo E, Della Puppa A, Abbadi S, Frasson C, Volpin F, Indraccolo S, Scienza R, Basso G. BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression. Cell Death Dis. 2012 Oct 18;3:e412. doi: 10.1038/cddis.2012.153. PubMed PMID: 23076220; PubMed Central PMCID: PMC3481140.

Lombardi G, Zustovich F, Farina P, Fiduccia P, Della Puppa A, Polo V, Bertorelle R, Gardiman MP, Banzato A, Ciccarino P, Denaro L, Zagonel V. Hypertension as a biomarker in patients with recurrent glioblastoma treated with antiangiogenic drugs: a single-center experience and a critical review of the literature. Anticancer Drugs. 2013 Jan;24(1):90-7. doi: 10.1097/CAD.0b013e32835aa5fd. Review. PubMed PMID: 23075631.

Jelcic N, De Pellegrin S, Cecchin D, Della Puppa A, Cagnin A. Cognitive improvement after cranioplasty: a possible volume transmission-related effect. Acta Neurochir (Wien). 2013 Aug;155(8):1597-9. doi: 10.1007/s00701-012-1519-6. Epub 2012 Oct 11. PubMed PMID: 23053292.

Manara R, Bommarito G, Rizzati S, Briani C, Della Puppa A, Citton V, Zanchetta E, Zerbo F, Ermani M, Martini C, Mantero F, Sicolo N, Maffei P, Scaroni C. Herniation of cerebellar tonsils in acromegaly: prevalence, pathogenesis and clinical impact. Pituitary. 2013 Mar;16(1):122-30. doi: 10.1007/s11102-012-0385-9. PubMed PMID: 22485017.

Lombardi G, Zustovich F, Farina P, Polo V, Farina M, Della Puppa A, Bertorelle R, Gardiman MP, Berti F, Zagonel V. Cilengitide in bevacizumab-refractory high-grade glioma: two case reports and critical review of the literature. Anticancer Drugs. 2012 Aug;23(7):749-53. doi: 10.1097/CAD.0b013e3283520e2c. Review. PubMed PMID: 22382388.

Manara R, Priante E, Grimaldi M, Santoro L, Polonara G, Parini R, Scarpa M; Italian MPS Neuroimaging Study Group. Closed Meningo(encephalo)cele: a new feature in Hunter syndrome. AJNR Am J Neuroradiol. 2012 May;33(5):873-7. doi: 10.3174/ajnr.A2867. Epub 2011 Dec 22. PubMed PMID: 22194384.

Persano L, Rampazzo E, Della Puppa A, Pistollato F, Basso G. The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications.2011;11:1829-41. doi: 10.1100/2011/736480. Epub 2011 Oct 23. Review. PubMed PMID: 22125441; PubMed Central PMCID: PMC3217608.

Bernardi D, Padoan A, Ballin A, Sartori M, Manara R, Scienza R, Plebani M, Della Puppa A.Serum YKL-40 following resection for cerebral glioblastoma. J Neurooncol. 2012 Apr;107(2):299-305. doi: 10.1007/s11060-011-0762-7. Epub 2011 Nov 19. PubMed PMID: 22102082.

Gardin C, Vindigni V, Bressan E, Ferroni L, Nalesso E, Della Puppa A, D'Avella D, Lops D, Pinton P, Zavan B. Hyaluronan and fibrin biomaterial as scaffolds for neuronal differentiation of adult stem cells derived from adipose tissue and skin. Int J Mol Sci. 2011;12(10):6749-64. doi: 10.3390/ijms12106749. Epub 2011 Oct 12. PubMed PMID: 22072917; PubMed Central PMCID: PMC3211008.

Ciccarino P, Rotilio A, Rossetto M, Manara R, Orvieto E, Berti F, Lombardi G, d'Avella D, Scienza R, Della Puppa A.Multifocal presentation of medulloblastoma in adulthood. J Neurooncol. 2012 Apr;107(2):233-7. doi: 10.1007/s11060-011-0746-7. Epub 2011 Nov 10. Review. PubMed PMID: 22071791.

D’Avella D, Della Puppa A.Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastomas. Acta Neurochir (Wien). 2012 Aug;154(8):1379-81. doi: 10.1007/s00701-012-1414-1.

Rossetto M, Magnaguagno F, Ciccarino P, Manara R, d'Avella D, Scienza R, Della Puppa A.Hemifacial spasm can be the presenting symptom of a fourth ventricle tumour. A short case-illustrated review and pathogenetic considerations. Acta Neurochir (Wien). 2011 Dec;153(12):2383-7. doi: 10.1007/s00701-011-1137-8. Epub 2011 Sep 2. Review. PubMed PMID: 21887494.

Della Puppa A, Rossetto M, Ciccarino P, Denaro L, Rotilio A, d'Avella D, Scienza R. Carmustine wafer implantation when surgical cavity is communicating with cerebral ventricles: technical considerations on a clinical series. World Neurosurg. 2011 Jul-Aug;76(1-2):156-9; discussion 67-8. doi: 10.1016/j.wneu.2010.10.024. PubMed PMID: 21839967.

Lombardi G, Zustovich F, Farina P, Della Puppa A, Manara R, Cecchin D, Brunello A, Cappetta A, Zagonel V. Neoplastic meningitis from solid tumors: new diagnostic and therapeutic approaches. 2011;16(8):1175-88. doi: 10.1634/theoncologist.2011-0101. Epub 2011 Jul 27. Review. PubMed PMID: 21795431; PubMed Central PMCID: PMC3228160.

Della Puppa A, Persano L, Masi G, Rampazzo E, Sinigaglia A, Pistollato F, Denaro L, Barzon L, Palù G, Basso G, Scienza R, d'Avella D. MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients? J Neurooncol. 2012 Jan;106(1):33-41. doi: 10.1007/s11060-011-0639-9. Epub 2011 Jul 2. PubMed PMID: 21725802.

Pistollato F, Persano L, Della Puppa A, Rampazzo E, Basso G. Isolation and expansion of regionally defined human glioblastoma cells in vitro. Curr Protoc Stem Cell Biol. 2011 May; Chapter 3: Unit 3.4. doi: 10.1002/9780470151808.sc0304s17. PubMed PMID: 21534253.

Della Puppa A, Denaro L, Rossetto M, Ciccarino P, Manara R, Lombardi G, Del Moro G, Rotilio A, d'Avella D, Scienza R. Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience. J Neurooncol. 2011 Nov;105(2):275-80. doi: 10.1007/s11060-011-0577-6. Epub 2011 Apr 20. PubMed PMID: 21505945.

Della Puppa, C. Gardin , L. Ferroni , G. Abatangelo, V. Vindigni, E. Bressan, B. Zavan. Cellule staminali:potenziale neurogenico della pelle e del tessuto adiposo. Laboratorio 2000. Aprile 2011; 50-54.

Della Puppa A, Rossetto M, Berti F, Zustovich F, Manara R, Gardiman MP, Scienza R. Internal auditory canal metastasis.J Neurosurg Sci. 2010 Dec;54(4):159-62. Review. PubMed PMID: 21423087.

Mardari R, Della Puppa A, Rotilio A, Sgarabotto D, Baracchini C, Carollo C, Manara R. Pontocerebellar angle aspergillosis: clinical and radiological findings. Neurologist. 2011 Mar;17(2):75-8. doi: 10.1097/NRL.0b013e3181e530a3. PubMed PMID: 21364357.

Manara R, Maffei P, Citton V, Rizzati S, Bommarito G, Ermani M, Albano I, Della Puppa A, Carollo C, Pavesi G, Scanarini M, Ceccato F, Sicolo N, Mantero F, Scaroni C, Martini C. Increased rate of intracranial saccular aneurysms in acromegaly: an MR angiography study and review of the literature. J Clin Endocrinol Metab. 2011 May;96(5):1292-300. doi: 10.1210/jc.2010-2721. Epub 2011 Feb 9. PubMed PMID: 21307138.

Lombardi G, Zustovich F, Della Puppa A, Borgato L, Orvieto E, Manara R, Cecchin D, Berti F, Farina P, Gardiman MP, Scienza R, Zagonel V. Cisplatin and temozolomide combination in the treatment of leptomeningeal carcinomatosis from ethmoid sinus intestinal-type adenocarcinoma. J Neurooncol. 2011 Aug;104(1):381-6. doi: 10.1007/s11060-010-0484-2. Epub 2010 Dec 8. PubMed PMID: 21140282.

Sartori MT, Della Puppa A, Ballin A, Saggiorato G, Bernardi D, Padoan A, Scienza R, d'Avella D, Cella G.Prothrombotic state in glioblastoma multiforme: an evaluation of the procoagulant activity of circulating microparticles.J Neurooncol. 2011 Aug;104(1):225-31. doi: 10.1007/s11060-010-0462-8. Epub 2010 Nov

Della Puppa A, Rossetto M, Scienza R. Use of a new absorbable sealing film for preventing postoperative cerebrospinal fluid leaks: remarks on a new approach. Br J Neurosurg. 2010 Oct;24(5):609-11. doi: 10.3109/02688697.2010.500413. PubMed PMID: 20868249.

Pistollato F, Rampazzo E, Persano L, Abbadi S, Frasson C, Denaro L, D'Avella D, Panchision DM, Della Puppa A, Scienza R, Basso G. Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate. Stem Cells. 2010 Nov;28(11):1918-29. doi: 10.1002/stem.518. PubMed PMID: 20827750; PubMed Central PMCID: PMC3474900.

Pistollato F, Abbadi S, Rampazzo E, Viola G, Della Puppa A, Cavallini L, Frasson C, Persano L, Panchision DM, Basso G. Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma. Biochem Pharmacol. 2010 Nov 15;80(10):1517-27. doi: 10.1016/j.bcp.2010.08.003. Epub 2010 Aug 10. PubMed PMID: 20705058.

Della Puppa A, Rossetto M, Ciccarino P, Del Moro G, Rotilio A, Manara R, Paola Gardiman M, Denaro L, d'Avella D, Scienza R. The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series. Acta Neurochir (Wien). 2010 Nov;152(11):1923-31. doi: 10.1007/s00701-010-0759-6. Epub 2010 Aug 13. PubMed PMID: 20703889.

Zavan B, Vindigni V, Gardin C, D'Avella D, Della Puppa A, Abatangelo G, Cortivo R. Neural potential of adipose stem cells. Discov Med. 2010 Jul;10(50):37-43. Review. PubMed PMID: 20670597.

Della Puppa A, Del Moro G, Tosatto L, Manara R, Orvieto E, Gardiman MP, Scienza R. Co-localisation of meningioma and craniopharyngioma mimicking a single skull base tumour in an elderly patient. J Neurooncol. 2011 Mar;102(1):167-70. doi: 10.1007/s11060-010-0300-z. Epub 2010 Jul 9. PubMed PMID: 20617364.

Frascara J, della Puppa A, Noël G, de Pellegrin S. A critique of visual materials in "Evidence for an occipito-temporal tract underlying visual recognition in picture naming". Clin Neurol Neurosurg. 2011 Jan;113(1):80-1; author reply 81. doi: 10.1016/j.clineuro.2010.05.014. Epub 2010 Jun 25. PubMed PMID: 20576348.

Santelli L, Ramondo G, Della Puppa A, Ermani M, Scienza R, d'Avella D, Manara R. Diffusion-weighted imaging does not predict histological grading in meningiomas. Acta Neurochir (Wien). 2010 Aug;152(8):1315-9; discussion 1319. doi: 10.1007/s00701-010-0657-y. Epub 2010 Apr 29. PubMed PMID: 20428902.

Pistollato F, Abbadi S, Rampazzo E, Persano L, Della Puppa A, Frasson C, Sarto E, Scienza R, D'avella D, Basso G. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma.Stem Cells. 2010 May;28(5):851-62. doi: 10.1002/stem.415. PubMed PMID: 20309962.

Zavan B, Michelotto L, Lancerotto L, Della Puppa A, D'Avella D, Abatangelo G, Vindigni V, Cortivo R. Neural potential of a stem cell population in the adipose and cutaneous tissues. Neurol Res. 2010 Feb;32(1):47-54. doi: 10.1179/174313209X385743. PubMed PMID: 20092695.

Della Puppa A, Fabbri M, Manara R, Carollo C, Salimbeni Fattorello C, D'Avella D, Scienza R. Venous stroke can be the unusual clinical presentation of an arising naso-ethmoidal encephalo-meningocele in adulthood. Neuroradiol J. 2009 Dec 14;22(5):554-7. Epub 2009 Dec 14. PubMed PMID: 24209400.

Zustovich F, Lombardi G, Della Puppa A, Rotilio A, Scienza R, Pastorelli D. A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma.Anticancer Res. 2009 Oct;29(10):4275-9. PubMed PMID: 19846986.

Della Puppa A, Dal Pos S, Zovato S, Orvieto E, Ciccarino P, Manara R, Zustovich F, Berti F, Gardiman MP, Scienza R. Solitary intra-ventricular brain metastasis from a breast carcinoma. J Neurooncol. 2010 Mar;97(1):123-6. doi: 10.1007/s11060-009-9988-z. Epub 2009 Sep 2. PubMed PMID: 19727563.

Vindigni V, Michelotto L, Lancerotto L, Della Puppa A, D'Avella D, Abatangelo G, Cortivo R, Zavan B. Isolation method for a stem cell population with neural potential from skin and adipose tissue. Neurol Res. 2009 Aug 5. [Epub ahead of print] PubMed PMID: 19660183.

Pistollato F, Rampazzo E, Abbadi S, Della Puppa A, Scienza R, D'Avella D, Denaro L, Te Kronnie G, Panchision DM, Basso G. Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. PLoS One. 2009 Jul 9;4(7):e6206. doi: 10.1371/journal.pone.0006206. PubMed PMID: 19587783; PubMed Central PMCID: PMC2702690.

Cecchin D, Chondrogiannis S, Della Puppa A, Rotilio A, Zustovich F, Manara R, Gardiman M, Berti F, Zucchetta P, Carollo C, Bui F. Presurgical (99m)Tc-sestamibi brain SPET/CT versus SPET: a comparison with MRI and histological data in 33 patients with brain tumours. Nucl Med Commun. 2009 Sep;30(9):660-8. doi: 10.1097/MNM.0b013e32832ea9b7. PubMed PMID: 19561554.

Della Puppa A, Mottaran R, Scienza R. Image-guided cranial osteoma resection and bioceramic porous hydroxyapatite custom-made reconstruction in a one-step surgical procedure. Technical notes and illustrative case. Acta Neurochir (Wien). 2010 Jan;152(1):155-9. doi: 10.1007/s00701-009-0374-6. Epub 2009 May 9. PubMed PMID: 19430722.

Zustovich F, Della Puppa A, Scienza R, Anselmi P, Furlan C, Cartei G. Metastatic oligodendrogliomas: a review of the literature and case report. Acta Neurochir (Wien). 2008 Jul;150(7):699-702; discussion 702-3. doi: 10.1007/s00701-008-1507-z. Epub 2008 Jun 12. Review. PubMed PMID: 18548193

Della Puppa A, Tosatto L, Amistà P, Munari M, Scienza R. Transverse sinus thrombosis after posterior fossa surgery for cerebellar tumor treated by endovascular thrombectomy. A case report. Neuroradiol J. 2007 Oct 31;20(5):562-5. Epub 2007 Oct 31. PubMed PMID: 24299946.

Della Puppa A, Zustovich F, Gardiman M, Manara R, Cecchin D, Scienza R. Haemorrhagic presentation of low-grade glioma in adults. Acta Neurochir (Wien). 2007 Nov;149(11):1151-5; discussion 1155. Epub 2007 Aug 6. Review. PubMed PMID: 17676407.

Zustovich F, Cartei G, Ceravolo R, Zovato S, Della Puppa A, Pastorelli D, Mattiazzi M, Bertorelle R, Gardiman MP. A phase I study of cisplatin, temozolomide and thalidomide in patients with malignant brain tumors. Anticancer Res. 2007 Mar-Apr;27(2):1019-24. PubMed PMID: 17465237.

Della Puppa A, G. Pavesi, R. Scienza Clinical and neurosurgical aspects of trigeminal neurinomas. Neurobiologia, 48, (5) ,321-324, 2001

Iob, A. Della Puppa, M. Vindigni, C. Ori Sinus Pericranii, a rare clinical emergency. Neurobiologia, 42, (4), 349-353, 1996.

Drigo P, Piovan S, Battistella PA, Della Puppa A, Burlina AB. Macrocephaly, subarachnoid fluid collection, and glutaric aciduria type I. J Child Neurol. 1996 Sep;11(5):414-7. PubMed PMID: 8877613.

C.Carollo, L.Rigobello, A.Della Puppa Cisti liquorali endocraniche: basi anatomo-patologiche e neuroradiologiche per un moderno inquadramento Rivista di Neuroradiologia 7: 221-229, 1994.

A. Della Puppa, P.Drigo, P.A.Battistella, A.B.Burlina, C.Carollo Aciduria glutarica I (GA I): reperti neuroradiologici caratteristici ed indicativi per una diagnosi precoce in 3 pazienti. Rivista di Neuroradiologia 7: 265-266, 1994.

A. Della Puppa, P.Drigo, I.Mammi, P.Amistà, R.Iavicoli, P.A.Battistella, C.Carollo. Angiomi cavernosi multipli cerebrali ed epatici. Inquadramento neuroradiologico di una famiglia portatrice di tale associazione Rivista di Neuroradiologia 6:419-427, 1993

Capitoli di Libri

Alessandro Della Puppa ”Malformazioni Vascolari Cerebrali“ in “Neurologia Clinica”. Società Editrice Esculapio. Bologna 2010.

Alessandro Della Puppa, Luca Persano. Stem Cell Distribution and MGMT expression in glioblastoma: role of intratumoural hypoxic gradient. In “Methods of Cancer Diagnosis, Therapy, and Prognosis” M.A. Hayat. Ed.Springer

Alessandro Della Puppa , Elena Porcù , Francesca Maule , and Giampietro Viola. “Glioblastoma Cancer Stem Cells”. In “Emerging Concepts and Future Perspectives in Translational Oncology” Sadegh Babashah Editor Ed.Springer

X

Alessandro DELLA PUPPA

Interessi

Interessi Clinici

Chirurgia oncologica cerebrale e spinale

Fluorescenza in neurochirurgia

Chirurgia con paziente sveglio (Awake Surgery)

Chirurgia del Basicranio

Chirurgia cerebro vascolare

Chirurgia dell'Epilessia

Neuromodulazione

Ricerca Clinica

Innovazione nelle tecniche di monitoraggio neurofisiologico intraoperatorio

Monitoraggio nella chirurgia cerebrovascolare

Applicazione della Stimolazione Magnetica Navigata Intra-operatoria nella chirurgia cerebrale

Endomicroscopia Confocale nella chirurgia cerebrale

Ricerca Preclinica

Studio e Modulazione del microambiente immunitario delle neoplasie cerebrali

Imaging Spettrale e Intelligenza Artificiale in Chirurgia Cerebrale (The Hyperprobe Project)

Alessandro DELLA PUPPA

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Ricciuti, Riccardo Antonio; Mancini, Fabrizio; Guzzi, Giusy; Marruzzo, Daniele; Dario, Alessandro; Puppa, Alessandro Della; Ricci, Alessandro; Barbanera, Andrea; Talacchi, Andrea; Schwarz, Andreas; Germanò, Antonino; Raco, Antonino; Colamaria, Antonio; Santoro, Antonio; Boccaletti, Riccardo; Conti, Carlo; Conti, Carlo; Cenci, Nunzia; Cossandi, Christian; Bernucci, Claudio; Lucantoni, Corrado; Costella, Giovanni Battista; Garbossa, Diego; Zotta, Donato Carlo; De Gonda, Federico; Esposito, Felice; Giordano, Flavio; D'Andrea, Giancarlo; Piatelli, Gianluca; Zona, Gianluigi; Spena, Giannantonio; Tringali, Giovanni; Barbagallo, Giuseppe; Giussani, Carlo; Gladi, Maurizio; Landi, Andrea; Lavano, Angelo; Morabito, Letterio; Mastronardi, Luciano; Locatelli, Marco; D'Agruma, Michele; Lanotte, Michele Maria; Montano, Nicola; Santonocito, Orazio Santo; Pompucci, Angelo; de Falco, Raffaele; Randi, Franco; Bruscella, Sara; Sartori, Ivana; Signorelli, Francesco; Tosatto, Luigino; Trignani, Roberto; Esposito, Vincenzo; Innocenzi, Gualtiero; Paolini, Sergio; Vitiello, Vincenzo; Cavallo, Michele Alessandro; Sala, Francesco (2024). The "state of the art" of intraoperative neurophysiological monitoring: An Italian neurosurgical survey. BRAIN AND SPINE, vol. 4, pp. 0-0, ISSN:2772-5294 DOI

Desideri, Isacco; Morelli, Ilaria; Banini, Marco; Greto, Daniela; Visani, Luca; Nozzoli, Filippo; Caini, Saverio; Della Puppa, Alessandro; Livi, Lorenzo; Perini, Zeno; Zivelonghi, Emanuele; Bulgarelli, Giorgia; Pinzi, Valentina; Navarria, Pierina; Clerici, Elena; Scorsetti, Marta; Ascolese, Anna Maria; Osti, Mattia Falchetto; Anselmo, Paola; Amelio, Dante; Minniti, Giuseppe; Scartoni, Daniele (2024). Re-irradiation for recurrent intracranial meningiomas: Analysis of clinical outcomes and prognostic factors. RADIOTHERAPY AND ONCOLOGY, vol. 195, pp. 0-0, ISSN:0167-8140 DOI

Muscas G, Bardazzi T, Pedone A, Campagnaro L, Bonaudo C, Fainardi E, Baldanzi F, Troiano S, Carrai R, Grippo A, Della Puppa A (2024). Heads-Up Micronavigation Reliability of Preoperative Transcranial Magnetic Stimulation Maps for the Motor Function: Comparison With Direct Cortical Stimulation. THE OPEN NEUROSURGERY JOURNAL, pp. 173-179, ISSN:1876-5297 DOI

Boschi, Andrea; Pisano, Antonio; Galletti, Anastasia; Grippo, Antonello; Fainardi, Enrico; Della Puppa, Alessandro (2024). Letter to the Editor Regarding "Carotid-Cavernous Fistula After Transsphenoidal Surgery: A Rare but Challenging Complication". WORLD NEUROSURGERY, vol. 187, pp. 247-250, ISSN:1878-8769 DOI

Elisa Castaldi, Camilla Bonaudo, Giuseppe Maduli, Giovanni Anobile, Agnese Pedone Federico Capelli, Roberto Arrighi, Alessandro Della Puppa (2024). Neurocognitive Assessment of Mathematics-Related Capacities in Neurosurgical Patients. BRAIN SCIENCES, pp. 0-0, ISSN:2076-3425 DOI

Giannoni L.; Bonaudo C.; Marradi M.; Della Puppa A.; Pavone F.S. (2023). Optical characterisation and study of ex vivo glioma tissue for hyperspectral imaging during neurosurgery. In: SPIE proceedings series, SPIE, vol. 12628, pp. 81-81, ISBN:9781510664654 DOI

Scola, Elisa; Del Vecchio, Guido; Busto, Giorgio; Bianchi, Andrea; Desideri, Ilaria; Gadda, Davide; Mancini, Sara; Carlesi, Edoardo; Moretti, Marco; Desideri, Isacco; Muscas, Giovanni; Della Puppa, Alessandro; Fainardi, Enrico (2023). Conventional and Advanced Magnetic Resonance Imaging Assessment of Non-Enhancing Peritumoral Area in Brain Tumor. CANCERS, vol. 15, pp. 2992-3016, ISSN:2072-6694 DOI

Muscas, Giovanni; Pisano, Antonio; Carrai, Riccardo; Bianchi, Andrea; Capelli, Federico; Montemurro, Vita Maria; Martinelli, Cristiana; Fainardi, Enrico; Grippo, Antonello; Della Puppa, Alessandro (2023). A Diffusion Tensor Imaging-Based Prognostic Classification for Surgery of Intrinsic Lesions Involving the Motor Pathways. WORLD NEUROSURGERY, pp. e565-e573, ISSN:1878-8750 DOI

Giannoni L.; Marradi M.; Marchetti M.; Degl'Innocenti D.R.; Ezhov I.; Caredda C.; Gautheron A.; Fort F.; Schneider F.; Berhouma M.; Bonaudo C.; Picart T.; Lange F.; Krischak K.; Gordebeke P.; Alfieri D.; Ruckert D.; Montcel B.; Della Puppa A.; Guyotat J.; Tachtsidis I.; Pavone F.S. (2023). HyperProbe consortium: innovate tumour neurosurgery with innovative photonic solutions. In: SPIE, SPIE, vol. 12628, pp. 47-47. DOI

Carrai, Riccardo; Martinelli, Cristiana; Baldanzi, Fabrizio; Gabbanini, Simonetta; Bonaudo, Camilla; Pedone, Agnese; Federico, Capelli; Caramelli, Riccardo; Spalletti, Maddalena; Lolli, Francesco; Grippo, Antonello; Bucciardini, Luca; Puppa, Alessandro Della; Ninone, Tommaso Agostino; Amadori, Andrea (2023). Is the Patient State Index a reliable parameter as guide to anaesthesiology in cranial neurosurgery? A first intraoperative study and a literature review. NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, vol. 53, pp. 102910-102918, ISSN:0987-7053 DOI

Carrai, Riccardo; Martinelli, Cristiana; Baldanzi, Fabrizio; Gabbanini, Simonetta; Gori, Benedetta; Masi, Giulia; Troiano, Simone; Bonaudo, Camilla; Esposito, Alice; Muscas, Giovanni; Tola, Serena; Caramelli, Riccardo; Spalletti, Maddalena; Lolli, Francesco; Grippo, Antonello; Bucciardini, Luca; Amadori, Andrea; Della Puppa, Alessandro (2022). Feasibility of Intraoperative Visual Evoked Potential Monitoring by Cortical Strip Electrodes in Patients During Brain Surgery: A Preliminary Study. WORLD NEUROSURGERY, pp. 0-5, ISSN:1878-8769 DOI

Detti B.; Scoccianti S.; Maragna V.; Lucidi S.; Ganovelli M.; Teriaca M.A.; Caini S.; Desideri I.; Agresti B.; Greto D.; Buccoliero A.M.; Della Puppa A.; Sardi I.; Livi L. (2022). Pleomorphic Xanthoastrocytoma: a single institution retrospective analysis and a review of the literature. LA RADIOLOGIA MEDICA, vol. 127, pp. 1134-1141, ISSN:0033-8362 DOI

Muscas, G; Orlandini, S; Bonaudo, C; Dardo, M; Esposito, A; Campagnaro, L; Carrai, R; Fainardi, E; Ciccarino, P; Della Puppa, A (2022). Functional outcomes, extent of resection, and bright/vague fluorescence interface in resection of glioblastomas involving the motor pathways assisted by 5-ALA. ACTA NEUROCHIRURGICA, pp. 3267-3274, ISSN:0001-6268 DOI

Petrella L.; Muscas G.; Montemurro V.M.; Lastrucci G.; Fainardi E.; Pansini G.; Della Puppa A. (2022). Use of the Subdural Hematoma in the Elderly (SHE) Score to Predict 30-Day Mortality After Chronic Subdural Hematoma Evacuation. WORLD NEUROSURGERY, vol. 157, pp. e294-e300, ISSN:1878-8750 DOI

Mazzeo, Salvatore; Emiliani, Filippo; Bagnoli, Silvia; Padiglioni, Sonia; Del Re, Lorenzo Maria; Giacomucci, Giulia; Balestrini, Juri; Ingannato, Assunta; Moschini, Valentina; Morinelli, Carmen; Galdo, Giulia; Polito, Cristina; Ferrari, Camilla; Pansini, Gastone; Della Puppa, Alessandro; Sorbi, Sandro; Nacmias, Benedetta; Bessi, Valentina (2022). Alzheimer's Disease CSF Biomarker Profiles in Idiopathic Normal Pressure Hydrocephalus. JOURNAL OF PERSONALIZED MEDICINE, vol. 12, pp. 935-948, ISSN:2075-4426 DOI

Muscas G.; Battista F.; Boschi A.; Morone F.; Della Puppa A. (2021). A Single-Center Experience with the Olympus ORBEYE 4K-3D Exoscope for Microsurgery of Complex Cranial Cases: Technical Nuances and Learning Curve. JOURNAL OF NEUROLOGICAL SURGERY. PART A, CENTRAL EUROPEAN NEUROSURGERY, pp. 0-0, ISSN:2193-6315 DOI

Hakiki, Bahia; Liuzzi, Piergiuseppe; Pansini, Gastone; Pancani, Silvia; Romoli, Annamaria; Draghi, Francesca; Orlandini, Simone; Mannini, Andrea; Della Puppa, Alessandro; Macchi, Claudio; Cecchi, Francesca (2021). Impact of decompressive craniectomy on functional outcome of severe acquired brain injuries patients, at discharge from intensive inpatient rehabilitation. DISABILITY AND REHABILITATION, pp. 1-7-7, ISSN:0963-8288 DOI

Arbula S.; Ambrosini E.; Della Puppa A.; De Pellegrin S.; Anglani M.; Denaro L.; Piccione F.; D'Avella D.; Semenza C.; Corbetta M.; Vallesi A. (2020). Focal left prefrontal lesions and cognitive impairment: A multivariate lesion-symptom mapping approach. NEUROPSYCHOLOGIA, vol. 136, pp. 107253-107265, ISSN:0028-3932 DOI

Pinton L.; Magri S.; Masetto E.; Vettore M.; Schibuola I.; Ingangi V.; Marigo I.; Matha K.; Benoit J.-P.; Della Puppa A.; Bronte V.; Lollo G.; Mandruzzato S. (2020). Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules. JOURNAL OF NANOBIOTECHNOLOGY, vol. 18, pp. 31-40, ISSN:1477-3155 DOI

Giovanni Muscas, Francesca Battista , Andrea Boschi , Bahman A Noubari , Alessandro Della Puppa (2020). Are familial colloid cysts of the third ventricle associated with a worse clinical course than sporadic forms? Case illustration and systematic literature review. JOURNAL OF NEUROSURGICAL SCIENCES, pp. 0-0, ISSN:0390-5616 DOI

Giovanni Muscas, Tommaso Matteuzzi, Eleonora Becattini, Simone Orlandini, Francesca Battista, Antonio Laiso, Sergio Nappini, Nicola Limbucci, Leonardo Renieri, Biagio R. Carangelo, Salvatore Mangiafico, Alessandro Della Puppa (2020). Development of machine learning models to prognosticate chronic shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage.. ACTA NEUROCHIRURGICA, pp. 3093-3105, ISSN:0001-6268

Susanna Mandruzzato, Laura Pinton, Elena Masetto, Marina Vettore, Camilla Bonaudo,Giuseppe Lombardi, Alessandro della Puppa (2020). Longitudinal evolution of the immune suppressive glioma microenvironment in different synchronous lesions during treatment. NEURO-ONCOLOGY ADVANCES, pp. 0-0, ISSN:2632-2498

Desideri I.; Becherini C.; Visani L.; Stocchi G.; Scoccimarro E.; Mariotti M.; Salvestrini V.; Scoccianti S.; Greto D.; Bonomo P.; Pecchioli G.; Bordi L.; Della Puppa A.; Francolini G.; Meattini I.; Livi L. (2020). Outcome and prognostic factors for older patients undergoing radiosurgery for brain metastases. JOURNAL OF GERIATRIC ONCOLOGY, pp. 31650-31659, ISSN:1879-4068 DOI

Giovanni Muscas, Francesca Battista, Giancarlo Lastrucci, Alessandro Della Puppa (2019). An alternative route to the posterior half of the third ventricle: the transoccipital horn approach. Technical note. WORLD NEUROSURGERY, vol. 132, pp. 223-229, ISSN:1878-8750 DOI

Anglani, Mariagiulia; Cecchin, Diego; Cester, Giacomo; Simonato, Davide; Baracchine, Claudio; Della Puppa, Alessandro; Causin, Francesco (2019). F-18-Fluorodeoxyglucose Positron Emission Tomography-Magnetic Resonance Monitoring of Brain Metabolic Changes in a Case of Arteriovenous Malformatione-Related Steal Phenomenon Symptoms. WORLD NEUROSURGERY, vol. 126, pp. 276-279, ISSN:1878-8750 DOI

Banzato T.; Causin F.; Della Puppa A.; Cester G.; Mazzai L.; Zotti A. (2019). Accuracy of Deep Learning to Differentiate the Histopathological Grading of Meningiomas on MR Images: A Preliminary Study. JOURNAL OF MAGNETIC RESONANCE IMAGING, vol. 50, pp. 1152-1159, ISSN:1053-1807 DOI Accesso ONLINE all'editore

Boschi, Andrea; Della Puppa, Alessandro (2019). 5-ALA fluorescence on tumors different from malignant gliomas. Review of the literature and our experience. JOURNAL OF NEUROSURGICAL SCIENCES, pp. 0-0, ISSN:0390-5616 DOI

Della Puppa A), Munari M, Gardiman MP, Volpin F. (2019). Combined Fluorescence Using 5-Aminolevulinic Acid and Fluorescein Sodium at Glioblastoma Border: Intraoperative Findings and Histopathologic Data About 3 Newly Diagnosed Consecutive Cases.. WORLD NEUROSURGERY, vol. 122, pp. 856-863, ISSN:1878-8750

Rustemi, Oriela; Della Puppa, Alessandro (2019). Hyperostosis and osteolysis in skull base meningiomas: are different nuances of 5-ALA fluorescence related to different invasion patterns?. JOURNAL OF NEUROSURGICAL SCIENCES, vol. 63, pp. 484-485, ISSN:0390-5616 DOI

Boso, Daniele; Rampazzo, Elena; Zanon, Carlo; Bresolin, Silvia; Maule, Francesca; Porcu, Elena; Cani, Alice; Della Puppa, Alessandro; Trentin, Luca; Basso, Giuseppe; Persano, Luca (2019). HIF-1 alpha/Wnt signaling-dependent control of gene transcription regulates neuronal differentiation of glioblastoma stem cells. THERANOSTICS, vol. 9, pp. 4860-4877, ISSN:1838-7640 DOI

Simonato, Davide; Gabrieli, Joseph; Domenico Cester, Giacomo; Della Puppa, Alessandro; Causin, Francesco (2019). Intracranial stenting after tumor exeresis complicated by delayed kinking of the middle cerebral artery. ACTA NEUROCHIRURGICA, vol. 161, pp. 593-596, ISSN:0942-0940 DOI

Indraccolo S, Lombardi G, Fassan M, Pasqualini L, Giunco S, Marcato , Gasparini A, Candiotto C, Nalio S, Fiduccia P, Fanelli GN, Pambuku A, Della Puppa A, D'Avella D), Bonaldi L, Gardiman MP, Bertorelle R, De Rossi A, Zagonel V (2019). Genetic, epigenetic and immunologic profiling of MMR-deficient relapsed glioblastoma. CLINICAL CANCER RESEARCH, vol. 25, pp. 1828-1837, ISSN:1078-0432 DOI

Pinton, Laura; Masetto, Elena:; Vettore, Marina; Solito, Samantha; Magri, Sara; D'Andolfi, Marta; Del Bianco, Paola; Lollo, Giovanna; Benoit, Jean-Pierre; Okada, Hideho; Diaz, Aaron; Della Puppa, Alessandro; Mandruzzato, Susanna (2019). The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion. JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 7, pp. 0-0, ISSN:2051-1426 DOI

Lombardi G.; Caccese M.; Bellu L.; Pambuku A.; Bergo E.; Berti F.; Gardiman M.P.; Della Puppa A.; Denaro L.; Dal Pos S.; Zagonel V. (2018). Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: Report of two cases. ANTI-CANCER DRUGS, vol. 29, pp. 924-928, ISSN:0959-4973 DOI

Pinton L.; Solito S.; Masetto E.; Vettore M.; Cane S.; Della Puppa A.; Mandruzzato S. (2018). Immunosuppressive activity of tumor-infiltrating myeloid cells in patients with meningioma. ONCOIMMUNOLOGY, vol. 7, pp. e1440931-e1440940, ISSN:2162-4011 DOI

Porcu E.; Maule F.; Boso D.; Rampazzo E.; Barbieri V.; Zuccolotto G.; Rosato A.; Frasson C.; Viola G.; Della Puppa A.; Basso G.; Persano L. (2018). BMP9 counteracts the tumorigenic and pro-angiogenic potential of glioblastoma. CELL DEATH AND DIFFERENTIATION, vol. 25, pp. 1808-1822, ISSN:1350-9047 DOI

Lombardi G, Della Puppa A, Gardiman MP, Rossi S, Candiotto C, Zanatta L,Bertorelle R, De Rossi A, Fassan M, Zagonel V. (2018). Discordance of IDH mutational status between lesions in an adult patient with multifocal glioma.. NEURO-ONCOLOGY, pp. 1142-1143, ISSN:1523-5866 DOI

Della Puppa, Alessandro; Rossetto, Marta; Volpin, Francesco; Rustemi, Oriela; Grego, Alberto; Gerardi, Alessandra; Ortolan, Riccardo; Causin, Francesco; Munari, Marina; Scienza, Renato (2018). Microsurgical Clipping of Intracranial Aneurysms Assisted by Neurophysiological Monitoring, Microvascular Flow Probe, and ICG-VA: Outcomes and Intraoperative Data on a Multimodal Strategy. WORLD NEUROSURGERY, vol. 113, pp. e336-e344-e344, ISSN:1878-8750 DOI

Milanese L, Martini C, Scaroni C, Dassie F, Ceccato F, Della Puppa A, Denaro L, Bommarito G, Citton V, Ermani M, Maffei P, Manara R. (2018). Radiotherapy in acromegaly: Long-term brain parenchymal and vascular magnetic resonance changes.. JOURNAL OF NEURORADIOLOGY, pp. 323-328, ISSN:0150-9861

Rustemi O, Scienza R, Della Puppa A. (2018). Tuberculum Sellae Meningioma Resection: Technical Nuances on the Frontopterional Approach.. JOURNAL OF NEUROLOGICAL SURGERY. PART B, SKULL BASE, pp. 225-226, ISSN:2193-634X

Pasqualin A, Meneghelli P, Musumeci A, Della Puppa A, Pavesi G, Pinna G, Scienza R (2018). Intraoperative Measurement of Arterial Blood Flow in Aneurysm Surgery. In: Esposito G., Regli L., Kaku Y., Tsukahara T. (eds). Trends in the Management of Cerebrovascular Diseases, pp. 43-52 Spriger, ISBN:978-3-319-73738-6. DOI

Della Puppa A, Rustemi O, Rampazzo E, Persano L. (2017). Combining 5-Aminolevulinic Acid Fluorescence and Intraoperative Magnetic Resonance Imaging in Glioblastoma Surgery: A Histology-Based Evaluation.. NEUROSURGERY ONLINE, pp. 12-12, ISSN:1524-4040

Rustemi O, Scienza R, Della Puppa A. (2017). Utility of indocyanine green videoangiography in subcortical arteriovenous malformation resection.. NEUROSURGICAL FOCUS, pp. 10-12, ISSN:1092-0684 DOI

Della Puppa A, Lombardi G, Rossetto M, Rustemi O, Berti F, Cecchin D, Gardiman MP, Rolma G, Persano L, Zagonel V, Scienza R. (2017). Outcome of patients affected by newly diagnosed glioblastoma undergoing surgery assisted by 5-aminolevulinic acid guided resection followed by BCNU wafers implantation: a 3-year follow-up.. JOURNAL OF NEURO-ONCOLOGY, pp. 331-340, ISSN:1573-7373

Talenti G, Vitale G, Cester G, Della Puppa A, Faggin R, Causin F. (2017). Rare association between spinal dural arteriovenous fistulas and dysraphisms: Report of two cases and review of the literature with a focus on pitfalls in diagnosis and treatment. INTERVENTIONAL NEURORADIOLOGY, pp. 458-464, ISSN:2385-2011

Rustemi O, Scienza R, Della Puppa A (2017). Indocyanine green videoangiography application in distal (M4) middle cerebral artery aneurysm surgery.. JOURNAL OF NEUROSURGICAL SCIENCES, pp. 351-354, ISSN:0390-5616

Rustemi O, Scienza R, Della Puppa A. (2017). The unusual subarachnoid hemorrhage presentation by a "sentinel" isolated trochlear nerve palsy of a posterior communicating artery aneurysm.. JOURNAL OF NEUROSURGICAL SCIENCES, pp. 444-446, ISSN:0390-5616 DOI

Vitale G, Talenti G, Gabrieli J, Cester G, Della Puppa A, Causin F. (2017). Endovascular rescue treatment through stent positioning after surgical clipping of intracranial aneurysms complicated by parent artery obstruction. BMJ CASE REPORT, pp. 1-2, ISSN:1757-790X

Rampazzo E, Dettin M, Maule F, Scabello A, Calvanese L, D'Auria G, Falcigno L, Porcù E, Zamuner A, Della Puppa A, Boso D, Basso G, Persano L (2017). A synthetic BMP-2 mimicking peptide induces glioblastoma stem cell differentiation.. BIOCHIMICA ET BIOPHYSICA ACTA. GENERAL SUBJECTS, pp. 2282-2292, ISSN:1872-8006

Della Puppa A, Rustemi O, Scienza R. (2017). The "ICG Entrapment Sign" in Cerebral Aneurysm Surgery Assisted by Indocyanine Green Videoangiography.. WORLD NEUROSURGERY, pp. 287-291, ISSN:1878-8769

Lombardi G, Pambuku A, Bellu L, Farina M, Della Puppa A, Denaro L, Zagonel V. (2017). Effectiveness of antiangiogenic drugs in glioblastoma patients: A systematic review and meta-analysis of randomized clinical trials.. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, pp. 94-102, ISSN:1040-8428 DOI

Semenza C, Salillas E, De Pallegrin S, Della Puppa A. (2017). Balancing the 2 Hemispheres in Simple Calculation: Evidence From Direct Cortical Electrostimulation.. CEREBRAL CORTEX, pp. 4806-4814, ISSN:1047-3211

Griguolo G, Dieci MV, Giarratano T, Giorgi CA, Orvieto E, Ghiotto C, Berti F, Della Puppa A, Falci C, Mioranza E, Tasca G, Milite N, Miglietta F, Scienza R, Conte P, Guarneri V. (2017). Beyond breast specific-Graded Prognostic Assessment in patients with brain metastases from breast cancer: treatment impact on outcome.. JOURNAL OF NEURO-ONCOLOGY, pp. 369-376, ISSN:1573-7373

Arbula S, Pacella V, De Pellegrin S, Rossetto M, Denaro L, D'Avella D, Della Puppa A, Vallesi A. (2017). Addressing the selective role of distinct prefrontal areas in response suppression: A study with brain tumor patients.. NEUROPSYCHOLOGIA, pp. 120-130, ISSN:0028-3932

Della Puppa A.; Scienza R. (2016). Multimodal flow-assisted resection of brain AVMs. In: Della Puppa A, Scienza R.. Acta Neurochirurgica, Supplementum, pp. 141-145 Springer-Verlag Wien, ISBN:978-3-319-29885-6. DOI

Bergo E, Lombardi G, Pambuku A, Della Puppa A, Bellu L, D'Avella D, Zagonel V. (2016). Cognitive Rehabilitation in Patients with Gliomas and Other Brain Tumors: State of the Art.. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, pp. 1-1, ISSN:1110-7251

Della Puppa A, Rustemi O, Scienza R. (2016). Intraoperative Flow Measurement by Microflow Probe During Spinal Dural Arteriovenous Fistula Surgery.. WORLD NEUROSURGERY, pp. 413-419, ISSN:1878-8769

Lombardi G, Della Puppa A, Zagonel V. (2016). Urine 2-Hydroxyglutarate in Glioma.. THE ONCOLOGIST, pp. 1026-1026, ISSN:1083-7159

Lombardi G, Bellu L, Pambuku A, Della Puppa A, Fiduccia P, Farina M, D'Avella D, Zagonel V. (2016). Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study.. JOURNAL OF NEURO-ONCOLOGY, pp. 481-486, ISSN:0167-594X

Rustemi O, Scienza R, Della Puppa A. (2016). ICG-VA application in subtemporal transtentorial treatment of a Cognard V dural arteriovenous fistula.. NEUROSURGICAL FOCUS, pp. 1-1, ISSN:1092-0684

Rustemi O, Gardiman MP, Scienza R, Della Puppa A. (2016). 5-ALA fluorescence applied to glioneuronal tumors.. ACTA NEUROCHIRURGICA, pp. 2123-2125, ISSN:0001-6268

Rossetto M, Ciccarino P, Lombardi G, Rolma G, Cecchin D, Della Puppa A. (2016). Surgery on motor area metastasis.. NEUROSURGICAL REVIEW, pp. 71-77, ISSN:0344-5607

Marin D, Pitteri M, Della Puppa A, Meneghello F, Biasutti E, Priftis K, Vallesi A. (2016). Mental time line distortion in right-brain-damaged patients: Evidence from a dynamic spatiotemporal task.. NEUROPSYCHOLOGY, pp. 338-345, ISSN:0894-4105

Maule F, Bresolin S, Rampazzo E, Boso D, Della Puppa A, Esposito G, Porcù E, Mitola S, Lombardi G, Accordi B, Tumino M, Basso G, Persano L. (2016). Annexin 2A sustains glioblastoma cell dissemination and proliferation.. ONCOTARGET, pp. 54632-54649, ISSN:1949-2553

Rustemi O, Scienza R, Della Puppa A. (2016). Intra-operative devascularization of petroclival meningiomas by ICG-VA-guided Bernasconi & Cassinari artery. ACTA NEUROCHIRURGICA, pp. 427-428, ISSN:0942-0940

Rustemi O, Cester G, Causin F, Scienza R, Della Puppa A. (2016). Indocyanine Green Videoangiography Transoptic Visualization and Clipping Confirmation of an Optic Splitting Ophthalmic Artery Aneurysm.. WORLD NEUROSURGERY, pp. 5-8, ISSN:1878-8769

Ferroni, Letizia; Gardin, Chiara; Della Puppa, Alessandro; Sivolella, Stefano; Brunello, Giulia; Scienza, Renato; Bressan, Eriberto; D'Avella, Domenico; Zavan, Barbara (2015). Novel Nanotechnologies for Brain Cancer Therapeutics and Imaging. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, vol. 11, pp. 1899-1912, ISSN:1550-7033

Cagnin A, Simioni M, Tagliapietra M, Citton V, Pompanin S, Della Puppa A, Ermani M, Manara R. (2015). A Simplified Callosal Angle Measure Best Differentiates Idiopathic-Normal Pressure Hydrocephalus from Neurodegenerative Dementia.. JOURNAL OF ALZHEIMER'S DISEASE, pp. 1033-1038, ISSN:1387-2877

Della Puppa A, Rustemi O, Scienza R. (2015). The suboccipital midline approach to foramen magnum meningiomas.. ACTA NEUROCHIRURGICA, pp. 869-873, ISSN:0001-6268

Lombardi G, Pace A, Pasqualetti F, Rizzato S, Faedi M, Anghileri E, Nicolotto E, Bazzoli E, Bellu L, Villani V, Fabi A, Ferrazza P, Gurrieri L, Dall'Agata M, Eoli M, Della Puppa A, Pambuku A, D'Avella D, Berti F, Rudà R, Zagonel V. (2015). Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy) irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology).. JOURNAL OF NEURO-ONCOLOGY, pp. 359-367, ISSN:0167-594X

Della Puppa A, Rustemi O, Scienza R. (2015). Letter to the editor: quality of life of patients affected by unruptured brain AVMs.. JOURNAL OF NEUROSURGERY, pp. 984-985, ISSN:0022-3085

Della Puppa A, De Pellegrin S, Rossetto M, Rustemi O, Saladini M, Munari M, Scienza R. (2015). Intraoperative functional mapping of calculation in parietal surgery. New insights and clinical implications.. ACTA NEUROCHIRURGICA, pp. 971-977, ISSN:0001-6268

Della Puppa A, Rustemi O, Scienza R. (2015). Intraoperative flow measurement by microflow probe during surgery for brain arteriovenous malformations. OPERATIVE NEUROSURGERY, pp. 268-273, ISSN:2332-4260

Della Puppa A, De Pellegrin S, Salillas E, Grego A, Lazzarini A, Vallesi A, Saladini M, Semenza C. (2015). Functional mapping of left parietal areas involved in simple addition and ultiplication. A single-case study of qualitative analysis of errors.. JOURNAL OF NEUROPSYCHOLOGY, pp. 330-335, ISSN:1748-6645

Sartore L, Venezia ED, Della Puppa A, Bedogni A, Campana L, Giatsidis G. (2015). Reconstructive strategies for dermatofibrosarcomas of the face: role of regenerative dermal templates. HEAD & NECK ONCOLOGY, pp. 8-11, ISSN:1758-3284

Ferroni L, Della Puppa A, D'Avella D, Isola M, Scienza R, Gardin C, Zavan B. (2015). Tissue Engineering Strategies as Tools for Personalized Meningioma Treatment. ARTIFICIAL ORGANS, pp. 114-126, ISSN:0160-564X

Della Puppa A, De Pellegrin S, Lazzarini A, Gioffrè G, Rustemi O, Cagnin A, Scienza R, Semenza C. (2015). Subcortical mapping of calculation processing in the right parietal lobe.. JOURNAL OF NEUROSURGERY, pp. 1038-1041, ISSN:0022-3085

Della Puppa A, d'Avella E, Rossetto M, Volpin F, Rustemi O, Gioffrè G,Lombardi G, Rolma G, Scienza R. (2015). Open Transcranial Resection of Small (<35 mm) Meningiomas of the Anterior Midline Skull Base in Current Microsurgical Practice.. WORLD NEUROSURGERY, pp. 741-750, ISSN:1878-8769

Della Puppa A, Rustemi O, Gioffrè G, Scienza R. (2015). Approaching a brainstem high-grade glioma (HGG) with the assistance of 5-aminolevulinic acid (5-ALA) technology: a new strategy for an old surgical challenge.. JOURNAL OF NEUROSURGICAL SCIENCES, pp. 797-799, ISSN:0390-5616

Della Puppa A, De Pellegrin S, Merola F, Rolma G, Vallesi A. (2015). Functional MRI and calculation processing: considerations on preliminary experience about intra-operative validation by electro-stimulation.. NEUROLOGICAL SCIENCES, pp. 1729-1731, ISSN:1590-3478

Lombardi G, Corona G, Bellu L, Della Puppa A, Pambuku A, Fiduccia P, Bertorelle R, Gardiman MP, D'Avella D, Toffoli G, Zagonel V. (2015). Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.. THE ONCOLOGIST, pp. 526-527, ISSN:1083-7159

Della Puppa A, Rustemi O, Scienza R. (2015). The suboccipital midline approach to foramen magnum meningiomas: safety and efficacy in a series of 23 consecutive patients over a 5-year period.. ACTA NEUROCHIRURGICA, pp. 1275-1276, ISSN:0001-6268

Lombardi G, Rumiato E, Bertorelle R, Saggioro D, Farina P, Della Puppa A,Zustovich F, Berti F, Sacchetto V, Marcato R, Amadori A, Zagonel V. (2015). Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study.. AMERICAN JOURNAL OF CLINICAL ONCOLOGY, pp. 514-519, ISSN:1537-453X

Della Puppa A, Rustemi O, Gioffrè G, Rolma G, Grandis M, Munari M, Scienza R. (2014). Application of indocyanine green video angiography in parasagittal meningioma surgery.. NEUROSURGICAL FOCUS, pp. 13-14, ISSN:1092-0684 DOI

Della Puppa A, Rustemi O, Gioffrè G. (2014). Is the intra-operative application of indocyanine green effective in retro-orbital surgery?. ACTA NEUROCHIRURGICA, pp. 1419-1420, ISSN:0001-6268

Della Puppa A, Rustemi O, Gioffrè G, Troncon I, Lombardi G, Rolma G, Sergi M, Munari M, Cecchin D, Gardiman MP, Scienza R. (2014). Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.. JOURNAL OF NEUROSURGERY, pp. 840-845, ISSN:0022-3085

Rampazzo E, Della Puppa A, Frasson C, Battilana G, Bianco S, Scienza R, Basso G, Persano L. (2014). Phenotypic and functional characterization of Glioblastoma cancer stem cells identified through 5-aminolevulinic acid-assisted surgery [corrected].. JOURNAL OF NEURO-ONCOLOGY, pp. 505-513, ISSN:1573-7373

Della Puppa A, Rustemi O, Gioffre' G. (2014). The rare event of optic-chiasmatic hemorrhagic low grade glioma in adulthood. Considerations on treatment strategy.. NEUROLOGICAL SCIENCES, pp. 623-625, ISSN:1590-3478 DOI

Della Puppa A, Rustemi O, Gioffrè G, Leoni L (2014). Brainstem surgery assisted by temporary trans-venous pacing to prevent severe bradycardia.. ACTA NEUROCHIRURGICA, pp. 431-432, ISSN:0001-6268

Della Puppa A, Gioffrè G, Gardiman MP, Frasson C, Cecchin D, Scienza R, Persano L. (2014). Intra-operative 5-aminolevulinic acid (ALA)-induced fluorescence of medulloblastoma: phenotypic variability and CD133(+) expression according to different fluorescence patterns. NEUROLOGICAL SCIENCES, pp. 99-102, ISSN:1590-3478

Della Puppa A, Volpin F, Gioffre G, Rustemi O, Troncon I, Scienza R. (2014). Microsurgical clipping of intracranial aneurysms assisted by green indocyanine videoangiography (ICGV) and ultrasonic perivascular microflow probe measurement.. CLINICAL NEUROLOGY AND NEUROSURGERY, pp. 35-40, ISSN:0303-8467

Manara R, Gabrieli J, Citton V, Ceccato F, Rizzati S, Bommarito G, Briani C, Della Puppa A, Dassie F, Milanese L, Di Salle F, Ermani M, Scaroni C, Martini C, Maffei P. (2014). Intracranial internal carotid artery changes in acromegaly: a quantitative magnetic resonance angiography study.. PITUITARY, pp. 414-422, ISSN:1386-341X

Della Puppa A, Rustemi O, Gioffrè G, Causin F, Scienza R. (2014). Transdural indocyanine green video-angiography of vascular malformations.. ACTA NEUROCHIRURGICA, pp. 1761-1767, ISSN:0001-6268

Della Puppa A, Rustemi O, Gioffrè G. (2014). Response.. JOURNAL OF NEUROSURGERY, pp. 766-768, ISSN:0022-3085

Lombardi G, Della Puppa A, Zustovich F, Pambuku A, Farina P, Fiduccia P, Roma A, Zagonel V. (2014). The combination of carmustine wafers and fotemustine in recurrent glioblastoma patients: a monoinstitutional experience.. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, pp. 1-1, ISSN:1110-7251

Della Puppa A, Rustemi O, Rossetto M, Gioffrè G, Munari M, Charbel FT, Scienza R. (2014). The "squeezing maneuver" in microsurgical clipping of intracranial aneurysms assisted by indocyanine green videoangiography.. OPERATIVE NEUROSURGERY, pp. 212-213, ISSN:2332-4260

Lombardi G, Della Puppa A, Di Stefano AL, Pace A, Rudà R, Tabouret E, Zagonel V. (2014). Gliomas. ACTA NEUROCHIRURGICA, pp. 1-1, ISSN:0001-6268

Lombardi G, Farina P, Della Puppa A, Cecchin D, Pambuku A, Bellu L, Zagonel V. (2014). An overview of fotemustine in high-grade gliomas: from single agent to association with bevacizumab.. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, pp. 1-1, ISSN:1110-7251

Stummer W, Rodrigues F, Schucht P, Preuss M, Wiewrodt D, Nestler U, Stein M, Artero JM, Platania N, Skjøth-Rasmussen J, Della Puppa A, Caird J, Cortnum S,Eljamel S, Ewald C, González-García L, Martin AJ, Melada A, Peraud A, Brentrup A,Santarius T, Steiner HH; European ALA Pediatric Brain Tumor Study Group. (2014). Predicting the "usefulness" of 5-ALA-derived tumor fluorescence for fluorescence-guided resections in pediatric brain tumors: a European survey.. ACTA NEUROCHIRURGICA, pp. 2315-2324, ISSN:0001-6268

Sivolella S, Brunello G, Ferrarese N, Della Puppa A, D'Avella D, Bressan E, Zavan B. (2014). Nanostructured guidance for peripheral nerve injuries: a review with a perspective in the oral and maxillofacial area.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, pp. 3088-3117, ISSN:1422-0067

Della Puppa A, Scienza R, Rustemi O, Gioffré G. (2014). Can the efficacy of indocyanine green videoangiography in cerebral arterio-venous malformations surgery be further improved?. OPERATIVE NEUROSURGERY, pp. 732-734, ISSN:2332-4260

Cecchin D, Schiorlin I, Della Puppa A, Lombardi G, Zucchetta P, Bodanza V, Gardiman MP, Rolma G, Frigo AC, Bui F. (2014). Assessing response using 99mTc-MIBI early after interstitial chemotherapy with carmustine-loaded polymers in glioblastoma multiforme: preliminary results.. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, pp. 1-1, ISSN:1110-7251

Della Puppa A, Ciccarino P, Lombardi G, Rolma G, Cecchin D, Rossetto M. (2014). 5-Aminolevulinic acid fluorescence in high grade glioma surgery: surgical outcome, intraoperative findings, and fluorescence patterns.. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, pp. 1-1, ISSN:1110-7251

G. Lombardi, G. Corona, P. Farina, A. Pambuku, L. Bellu, A. Della Puppa, P., Fiduccia, R., Bertorelle, M. P. Gardiman, G. Toffoli, V. Zagonel. (2014). Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with IDH-mutated glioma. ASCO 2014. THE ONCOLOGIST, pp. 562-567, ISSN:1083-7159

Lombardi G, Pambuku A, Bellu L, Della Puppa A, Rumanò L, Gardiman MP, Pomerri F, Zagonel V. (2013). Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma.. CHEMOTHERAPY, pp. 176-180, ISSN:1421-9794

Rossetto M, Persano L, Scienza R, Della Puppa A. (2013). Hydrocephalus after meningioma surgery.. NEUROSURGICAL FOCUS, pp. 8-9, ISSN:1092-0684

Jelcic N, Della Puppa A, Mottaran R, Cecchin D, Manara R, Dam M, Cagnin A. (2013). Case series evidence for improvement of executive functions after late cranioplasty.. BRAIN INJURY, pp. 1723-1726, ISSN:1362-301X

Della Puppa A., Scienza R. (2013). 5-Aminolevulinic acid-guided resection of bone-invasive meningiomas.. NEUROSURGICAL FOCUS, pp. 6-7, ISSN:1092-0684 DOI

Della Puppa A, De Pellegrin S, d'Avella E, Gioffrè G, Munari M, Saladini M,Salillas E, Scienza R, Semenza C. (2013). Right parietal cortex and calculation processing: intraoperative functional mapping of multiplication and addition in patients affected by a brain tumor.. JOURNAL OF NEUROSURGERY, pp. 1107-1111, ISSN:0022-3085

Sartori MT, Della Puppa A, Ballin A, Campello E, Radu CM, Saggiorato G, d'Avella D, Scienza R, Cella G, Simioni P. (2013). Circulating microparticles of glial origin and tissue factor bearing in high-grade glioma: a potential prothrombotic role.. THROMBOSIS AND HAEMOSTASIS, pp. 378-385, ISSN:0340-6245

Manara R, Bommarito G, Rizzati S, Briani C, Della Puppa A, Citton V, Zanchetta E, Zerbo F, Ermani M, Martini C, Mantero F, Sicolo N, Maffei P, Scaroni C. (2013). Herniation of cerebellar tonsils in acromegaly: prevalence, pathogenesis and clinical impact.. PITUITARY, pp. 122-130, ISSN:1386-341X

Della Puppa A, De Pellegrin S, d'Avella E, Gioffrè G, Rossetto M, Gerardi A, Lombardi G, Manara R, Munari M, Saladini M, Scienza R. (2013). 5-aminolevulinic acid (5-ALA) fluorescence guided surgery of high-grade gliomas in eloquent areas assisted by functional mapping. Our experience and review of the literature.. ACTA NEUROCHIRURGICA, pp. 965-972, ISSN:0001-6268

Rampazzo E, Persano L, Pistollato F, Moro E, Frasson C, Porazzi P, Della Puppa A, Bresolin S, Battilana G, Indraccolo S, Te Kronnie G, Argenton F, Tiso N, Basso G. (2013). Wnt activation promotes neuronal differentiation of glioblastoma.. CELL DEATH & DISEASE, pp. 502-505, ISSN:2041-4889

d'Avella E, Volpin F, Manara R, Scienza R, Della Puppa A. (2013). Indocyanine green videoangiography (ICGV)-guided surgery of parasagittal meningiomas occluding the superior sagittal sinus (SSS).. ACTA NEUROCHIRURGICA, pp. 415-420, ISSN:0001-6268

Lombardi G, Zustovich F, Farina P, Fiduccia P, Della Puppa A, Polo V, Bertorelle R, Gardiman MP, Banzato A, Ciccarino P, Denaro L, Zagonel V. (2013). Hypertension as a biomarker in patients with recurrent glioblastoma treated with antiangiogenic drugs: a single-center experience and a critical review of the literature.. ANTI-CANCER DRUGS, pp. 90-97, ISSN:0959-4973

Jelcic N, De Pellegrin S, Cecchin D, Della Puppa A, Cagnin A. (2013). Cognitive improvement after cranioplasty: a possible volume transmission-related effect.. ACTA NEUROCHIRURGICA, pp. 1597-1599, ISSN:0001-6268

Della Puppa A, d'Avella E, Volpin F, Rustemi O, Gioffre' G, Scienza R. (2013). Indocyanine green videoangiography (ICGV) in parasagittal meningiomas surgery. Considerations on veins management and brain function preservation.. ACTA NEUROCHIRURGICA, pp. 1475-1476, ISSN:0001-6268

Persano L, Pistollato F, Rampazzo E, Della Puppa A, Abbadi S, Frasson C, Volpin F, Indraccolo S, Scienza R, Basso G. (2012). BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression.. CELL DEATH & DISEASE, pp. 412-413, ISSN:2041-4889

Della Puppa A, Persano L, Masi G, Rampazzo E, Sinigaglia A, Pistollato F,Denaro L, Barzon L, Palù G, Basso G, Scienza R, d'Avella D. (2012). MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?. JOURNAL OF NEURO-ONCOLOGY, pp. 33-41, ISSN:0167-594X

Bernardi D, Padoan A, Ballin A, Sartori M, Manara R, Scienza R, Plebani M, Della Puppa A. (2012). Serum YKL-40 following resection for cerebral glioblastoma.. JOURNAL OF NEURO-ONCOLOGY, pp. 299-305, ISSN:0167-594X

Ciccarino P, Rotilio A, Rossetto M, Manara R, Orvieto E, Berti F, Lombardi G, d'Avella D, Scienza R, Della Puppa A. (2012). Multifocal presentation of medulloblastoma in adulthood.. JOURNAL OF NEURO-ONCOLOGY, pp. 233-237, ISSN:0167-594X

Lombardi G, Zustovich F, Farina P, Polo V, Farina M, Della Puppa A,Bertorelle R, Gardiman MP, Berti F, Zagonel V. (2012). Cilengitide in bevacizumab-refractory high-grade glioma: two case reports and critical review of the literature.. ANTI-CANCER DRUGS, pp. 749-753, ISSN:0959-4973

d'Avella D. , Della Puppa A. (2012). Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastomas.. ACTA NEUROCHIRURGICA, pp. 1379-1381, ISSN:0001-6268

Rossetto M, Magnaguagno F, Ciccarino P, Manara R, d'Avella D, Scienza R, Della Puppa A. (2011). Hemifacial spasm can be the presenting symptom of a fourth ventricle tumour. A short case-illustrated review and pathogenetic considerations. ACTA NEUROCHIRURGICA, pp. 2383-2387, ISSN:0001-6268

Della Puppa A, Rossetto M, Ciccarino P, Denaro L, Rotilio A, d'Avella D, Scienza R. (2011). Carmustine wafer implantation when surgical cavity is communicating with cerebral ventricles: technical considerations on a clinical series.. WORLD NEUROSURGERY, pp. 156-159, ISSN:1878-8769

Frascara J, della Puppa A, Noël G, de Pellegrin S. (2011). A critique of visual materials in "Evidence for an occipito-temporal tract underlying visual recognition in picture naming".. CLINICAL NEUROLOGY AND NEUROSURGERY, pp. 80-81, ISSN:0303-8467 DOI

Gardin C, Vindigni V, Bressan E, Ferroni L, Nalesso E, Della Puppa A, D'Avella D, Lops D, Pinton P, Zavan B. (2011). Hyaluronan and fibrin biomaterial as scaffolds for neuronal differentiation of adult stem cells derived from adipose tissue and skin.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, pp. 6749-6764, ISSN:1422-0067

D'Avella D.; Della Puppa A. (2011). Application of intraoperative indocyanine green videoangiography to brain tumor surgery: Commentary. ACTA NEUROCHIRURGICA, vol. 153, pp. 1494-1495, ISSN:0001-6268 DOI

Lombardi G, Zustovich F, Farina P, Della Puppa A, Manara R, Cecchin D, Brunello A, Cappetta A, Zagonel V. (2011). Neoplastic meningitis from solid tumors: new diagnostic and therapeutic approaches. THE ONCOLOGIST, pp. 1175-1188, ISSN:1083-7159

D'Avella D.; Della Puppa A. (2011). Occlusion of surgical opening of the ventricular system with fibrinogen-coated collagen fleece: A case collection study - Commentary. ACTA NEUROCHIRURGICA, vol. 153, pp. 539-539, ISSN:0001-6268 DOI

Sartori MT, Della Puppa A, Ballin A, Saggiorato G, Bernardi D, Padoan A,Scienza R, d'Avella D, Cella G. (2011). Prothrombotic state in glioblastoma multiforme:an evaluation of the procoagulant activity of circulating microparticles.. JOURNAL OF NEURO-ONCOLOGY, pp. 225-231, ISSN:1573-7373

Mardari R, Della Puppa A, Rotilio A, Sgarabotto D, Baracchini C, Carollo C, Manara R. (2011). Pontocerebellar angle aspergillosis: clinical and radiological findings.. NEUROLOGIST, pp. 75-78, ISSN:1074-7931

Manara R, Maffei P, Citton V, Rizzati S, Bommarito G, Ermani M, Albano I,Della Puppa A, Carollo C, Pavesi G, Scanarini M, Ceccato F, Sicolo N, Mantero F, Scaroni C, Martini C. (2011). Increased rate of intracranial saccular aneurysms in acromegaly: an MR angiography study and review of the literature.. THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, pp. 1292-1300, ISSN:0021-972X

Pistollato F, Persano L, Della Puppa A, Rampazzo E, Basso G. (2011). Isolation and expansion of regionally defined human glioblastoma cells in vitro.. CURRENT PROTOCOLS IN STEM CELL BIOLOGY, pp. 1-10, ISSN:1941-7322

Della Puppa A, Denaro L, Rossetto M, Ciccarino P, Manara R, Lombardi G, Del Moro G, Rotilio A, d'Avella D, Scienza R. (2011). Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.. JOURNAL OF NEURO-ONCOLOGY, pp. 275-280, ISSN:1573-7373

Lombardi G, Zustovich F, Della Puppa A, Borgato L, Orvieto E, Manara R, Cecchin D, Berti F, Farina P, Gardiman MP, Scienza R, Zagonel V. (2011). Cisplatin and temozolomide combination in the treatment of leptomeningeal carcinomatosis from ethmoid sinus intestinal-type adenocarcinoma.. JOURNAL OF NEURO-ONCOLOGY, pp. 381-386, ISSN:1573-7373

Persano L, Rampazzo E, Della Puppa A, Pistollato F, Basso G. (2011). The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications. THE SCIENTIFIC WORLD JOURNAL, pp. 1829-1841, ISSN:1537-744X

Della Puppa A, Del Moro G, Tosatto L, Manara R, Orvieto E, Gardiman MP, Scienza R. (2011). Co-localisation of meningioma and craniopharyngioma mimicking a single skull base tumour in an elderly patient.. JOURNAL OF NEURO-ONCOLOGY, pp. 167-170, ISSN:1573-7373

Della Puppa A, Rossetto M, Scienza R. (2010). Use of a new absorbable sealing film for preventing postoperative cerebrospinal fluid leaks: remarks on a new approach.. BRITISH JOURNAL OF NEUROSURGERY, pp. 609-611, ISSN:1360-046X

Pistollato F, Rampazzo E, Persano L, Abbadi S, Frasson C, Denaro L, D'Avella D, Panchision DM, Della Puppa A, Scienza R, Basso G. (2010). Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate.. STEM CELLS TRANSLATIONAL MEDICINE, pp. 1918-1929, ISSN:2157-6564

Zavan B, Michelotto L, Lancerotto L, Della Puppa A, D'Avella D, Abatangelo G, Vindigni V, Cortivo R. (2010). neural potential of a stem cell population in the adipose and cutaneous tissues.. NEUROLOGICAL RESEARCH, pp. 47-54, ISSN:0161-6412

Della Puppa A, Rossetto M, Ciccarino P, Del Moro G, Rotilio A, Manara R,Paola Gardiman M, Denaro L, d'Avella D, Scienza R. (2010). The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series.. ACTA NEUROCHIRURGICA, pp. 1923-1931, ISSN:0001-6268

Pistollato F, Abbadi S, Rampazzo E, Viola G, Della Puppa A, Cavallini L, Frasson C, Persano L, Panchision DM, Basso G. (2010). Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma.. BIOCHEMICAL PHARMACOLOGY, pp. 1517-1527, ISSN:0006-2952

Della Puppa A, Dal Pos S, Zovato S, Orvieto E, Ciccarino P, Manara R,Zustovich F, Berti F, Gardiman MP, Scienza R. (2010). Solitary intra-ventricular brain metastasis from a breast carcinoma.. JOURNAL OF NEURO-ONCOLOGY, pp. 123-126, ISSN:1573-7373

Zavan B, Vindigni V, Gardin C, D'Avella D, Della Puppa A, Abatangelo G,Cortivo R. (2010). Neural potential of adipose stem cells.. DISCOVERY MEDICINE, pp. 37-43, ISSN:1944-7930

Della Puppa A, Mottaran R, Scienza R. (2010). Image-guided cranial osteoma resection and bioceramic porous hydroxyapatite custom-made reconstruction in a one-step surgical procedure. Technical notes and illustrative case.. ACTA NEUROCHIRURGICA, pp. 155-159, ISSN:0001-6268

Pistollato F, Abbadi S, Rampazzo E, Persano L, Della Puppa A, Frasson C, Sarto E, Scienza R, D'avella D, Basso G. (2010). Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma.. STEM CELLS TRANSLATIONAL MEDICINE, pp. 851-862, ISSN:2157-6564

Della Puppa A, Rossetto M, Berti F, Zustovich F, Manara R, Gardiman MP, Scienza R. (2010). Internal auditory canal metastasis.. ASIAN JOURNAL OF NEUROSURGERY, pp. 159-162, ISSN:2248-9614

Santelli L, Ramondo G, Della Puppa A, Ermani M, Scienza R, d'Avella D,Manara R. (2010). Diffusion-weighted imaging does not predict histological grading in meningiomas.. ACTA NEUROCHIRURGICA, pp. 1315-1319, ISSN:0001-6268

Pistollato F, Rampazzo E, Abbadi S, Della Puppa A, Scienza R, D'Avella D,Denaro L, Te Kronnie G, Panchision DM, Basso G (2009). Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. PLOS ONE, pp. 6206-6206, ISSN:1932-6203 DOI

Della Puppa A, Fabbri M, Manara R, Carollo C, Salimbeni Fattorello C,D'Avella D, Scienza R. (2009). Venous stroke can be the unusual clinical presentation of an arising naso-ethmoidal encephalo-meningocele in adulthood.. JOURNAL OF NEURORADIOLOGY, pp. 554-557, ISSN:0150-9861

Vindigni V, Michelotto L, Lancerotto L, Della Puppa A, D'Avella D, Abatangelo G, Cortivo R, Zavan B. (2009). Isolation method for a stem cell population with neural potential from skin and adipose tissue.. NEUROLOGICAL RESEARCH, pp. 1-1, ISSN:0161-6412

Cecchin D, Chondrogiannis S, Della Puppa A, Rotilio A, Zustovich F, Manara R, Gardiman M, Berti F, Zucchetta P, Carollo C, Bui F. (2009). Presurgical (99m)Tc-sestamibi brain SPET/CT versus SPET: a comparison with MRI and histological data in 33 patients with brain tumours. NUCLEAR MEDICINE COMMUNICATIONS, pp. 660-668, ISSN:0143-3636

Zustovich F, Lombardi G, Della Puppa A, Rotilio A, Scienza R, Pastorelli D. (2009). A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma.. ANTICANCER RESEARCH, pp. 4275-4279, ISSN:0250-7005

Zustovich F, Della Puppa A, Scienza R, Anselmi P, Furlan C, Cartei G. (2008). Metastatic oligodendrogliomas: a review of the literature and case report.. ACTA NEUROCHIRURGICA, pp. 699-702, ISSN:0001-6268

Della Puppa A, Tosatto L, Amistà P, Munari M, Scienza R. (2007). Transverse sinus thrombosis after posterior fossa surgery for cerebellar tumor treated by endovascular thrombectomy. A case report.. JOURNAL OF NEURORADIOLOGY, pp. 562-565, ISSN:0150-9861

Della Puppa A, Zustovich F, Gardiman M, Manara R, Cecchin D, Scienza R. (2007). Haemorrhagic presentation of low-grade glioma in adults. ACTA NEUROCHIRURGICA, pp. 1151-1155, ISSN:0001-6268

Zustovich F, Cartei G, Ceravolo R, Zovato S, Della Puppa A, Pastorelli D,Mattiazzi M, Bertorelle R, Gardiman MP. (2007). A phase I study of cisplatin,temozolomide and thalidomide in patients with malignant brain tumors.. ANTICANCER RESEARCH, pp. 1019-1024, ISSN:0250-7005

Drigo P, Piovan S, Battistella PA, Della Puppa A, Burlina AB. (1996). Macrocephaly, subarachnoid fluid collection, and glutaric aciduria type I.. JOURNAL OF CHILD NEUROLOGY, pp. 414-417, ISSN:1708-8283 DOI

Alessandro DELLA PUPPA

Biography

Born in Venice (Italy), the 28th April 1967.

Degree in Medicine at the School of Medicine of the University of Padova, Italy.

Medical School of the Italian Army Academy (1994)

Medical Officer at the Military Hospital of Padova (1994-1995).

Residency in Neurosurgery at the University of Padova (1995-2000)

From 2000 to 2018 clinical activity as Hospitalist at the Department of Neurosurgery at the University Hospital of Padova

Associate Professor in Neurosurgery at the University of Florence from 2018

From 2019 Director of Residency Program in Neurosurgery of the University of Florence

Full Professor in Neurosurgery at the University of Florence from 2023

Alessandro DELLA PUPPA

Interest

Clinical Interests

Brain Tumor Surgery

Fluorescence in Brain Tumour Surgery

Awake Surgery

Cranial Base Surgery

Cerebrovascular surgery

Epilepsy Surgery

Neuromodulation

Clinical Research

Innovations in intraoperative neurophysiological monitoring

Monitoring in vascular surgery

Navigated Trans Cranial Magnetic Stimulation in Brain surgery

Confocal Endomicroscopy in Brain Tumor Surgery

Preclinical Research

Immunomodulation of brain tumour microenvironment

Spectral Imaging and Artificial Intelligence in Brain Surgery (The Hyperprobe Project)