Toti A.; Kura A.; Sticchi E.; Duvina M.; Balestri V.; Amunni F.; Tonelli P.; Di Cesare Mannelli L.; Ghelardini C.; Parisi E. (2025). Biomarkers during early healing of extraction procedures: a prospective case series. CLINICAL ORAL INVESTIGATIONS, vol. 29, pp. 0-0, ISSN:1436-3771 DOI  

  Toti A.; Lucarini E.; Ferrara V.; Parisio C.; Ciampi C.; Gerace E.; Micheli L.; Margiotta F.; Venturi D.; Mello T.; Lacal P.M.; Graziani G.; Mannaioni G.; Ghelardini C.; Di Cesare Mannelli L. (2025). The dual role of VEGF-A in a complex in vitro model of oxaliplatin-induced neurotoxicity: Pain-related and neuroprotective effects. NEUROTHERAPEUTICS, vol. 22, pp. 0-0, ISSN:1878-7479 DOI  

  Micheli, Laura; Balayssac, David; Busserolles, Jérôme; Dalbos, Cristelle; Prival, Laetitia; Richard, Damien; Quintana, Mercedes; Di Cesare Mannelli, Lorenzo; Toti, Alessandra; Ciampi, Clara; Ghelardini, Carla; Vlasakova, Katerina; Glaab, Warren E.; Hu, Yang; Loryan, Irena; Perrault, Olivier; Slaoui, Mohamed; Wuersch, Kuno; Johnson, Eric; Frieauff, Wilfried; Penraat, Kelley; Brees, Dominique; Dubost, Valérie; Theil, Diethilde (2025). The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project). TOXICOLOGY, vol. 510, pp. 0-0, ISSN:0300-483X DOI  

  Micheli, Laura; Toti, Alessandra; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Crocetti, Letizia; Farina, Carlo; Scherz, Michael (2024). Synthesis and Anti‐Hyperalgesic Efficacy of MP‐103, a Non‐Racemic Enantiomeric Mixture of a New 1,4‐Diazabicyclo[4.3.0]nonan‐9‐one. CHEMISTRYSELECT, vol. 9, pp. 0-0, ISSN:2365-6549 DOI  

  Nobili, Stefania; Micheli, Laura; Lucarini, Elena; Toti, Alessandra; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo (2024). Ultramicronized N-palmitoylethanolamine associated with analgesics: Effects against persistent pain. PHARMACOLOGY & THERAPEUTICS, vol. 258, pp. 0-0, ISSN:0163-7258 DOI  

  Micheli, Laura; Nobili, Stefania; Lucarini, Elena; Toti, Alessandra; Margiotta, Francesco; Ciampi, Clara; Venturi, Daniel; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2024). New insights in the mechanisms of opioid analgesia and tolerance: Ultramicronized palmitoylethanolamide down-modulates vascular endothelial growth factor-A in the nervous system. PHARMACOLOGICAL RESEARCH, vol. 209, pp. 0-0, ISSN:1043-6618 DOI  

  Ferrara V.; Toti A.; Lucarini E.; Parisio C.; Micheli L.; Ciampi C.; Margiotta F.; Crocetti L.; Vergelli C.; Giovannoni M.P.; Di Cesare Mannelli L.; Ghelardini C. (2023). Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis. ANTIOXIDANTS, vol. 12, pp. 1207-1226, ISSN:2076-3921 DOI  

  Lucarini E.; Micheli L.; Toti A.; Ciampi C.; Margiotta F.; Di Cesare Mannelli L.; Ghelardini C. (2023). Anti-Hyperalgesic Efficacy of Acetyl L-Carnitine (ALCAR) Against Visceral Pain Induced by Colitis: Involvement of Glia in the Enteric and Central Nervous System. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 0-0, ISSN:1422-0067 DOI  

  Lucarini E, Di Pilato V, Parisio C, Micheli L, Toti A, Pacini A, Bartolucci G, Baldi S, Niccolai E, Amedei A, Rossolini GM, Nicoletti C, Cryan JF, O'Mahony SM, Ghelardini C, Di Cesare Mannelli L. (2022). Visceral sensitivity modulation by faecal microbiota transplantation: the active role of gut bacteria in pain persistence. PAIN, pp. 1-17, ISSN:1872-6623

  Bonardi, Alessandro; Bua, Silvia; Combs, Jacob; Lomelino, Carrie; Andring, Jacob; Osman, Sameh Mohamed; Toti, Alessandra; Di Cesare Mannelli, Lorenzo; Gratteri, Paola; Ghelardini, Carla; McKenna, Robert; Nocentini, Alessio; Supuran, Claudiu T (2022). The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 37, pp. 930-939-939, ISSN:1475-6366 DOI  

  Micheli, Laura; Lucarini, Elena; Nobili, Stefania; Bartolucci, Gianluca; Pallecchi, Marco; Toti, Alessandra; Ferrara, Valentina; Ciampi, Clara; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo (2022). Ultramicronized N-palmitoylethanolamine contributes to morphine efficacy against neuropathic pain: implication of mast cells and glia. CURRENT NEUROPHARMACOLOGY, vol. 21, pp. 0-0, ISSN:1570-159X DOI  

  Micheli L.; Parisio C.; Lucarini E.; Carrino D.; Ciampi C.; Toti A.; Ferrara V.; Pacini A.; Ghelardini C.; Di Cesare Mannelli L. (2022). Restorative and pain-relieving effects of fibroin in preclinical models of tendinopathy. BIOMÉDECINE & PHARMACOTHÉRAPIE, vol. 148, pp. 112693-112693, ISSN:0753-3322 DOI  

  Lucarini E.; Micheli L.; Pagnotta E.; Toti A.; Ferrara V.; Ciampi C.; Margiotta F.; Martelli A.; Testai L.; Calderone V.; Matteo R.; Suriano S.; Troccoli A.; Pecchioni N.; Manera C.; Di Cesare Mannelli L.; Ghelardini C. (2022). The Efficacy of Camelina sativa Defatted Seed Meal against Colitis-Induced Persistent Visceral Hypersensitivity: The Relevance of PPAR α Receptor Activation in Pain Relief. NUTRIENTS, vol. 14, pp. 3137-3137, ISSN:2072-6643 DOI  

  Di Cesare Mannelli, Lorenzo; Micheli, Laura; Cervetto, Chiara; Toti, Alessandra; Lucarini, Elena; Parisio, Carmen; Marcoli, Manuela; Ghelardini, Carla (2022). Neuronal alarmin IL-1α evokes astrocyte-mediated protective signals: Effectiveness in chemotherapy-induced neuropathic pain. NEUROBIOLOGY OF DISEASE, vol. 168, pp. 105716-105716, ISSN:0969-9961 DOI  

  Lucarini E.; Micheli L.; Pagnotta E.; Matteo R.; Parisio C.; Toti A.; Ferrara V.; Ciampi C.; Martelli A.; Testai L.; Calderone V.; Savino M.; Russo M.; Pecchioni N.; Ghelardini C.; Di Cesare Mannelli L. (2022). Beneficial Effects of Eruca sativa Defatted Seed Meal on Visceral Pain and Intestinal Damage Resulting from Colitis in Rats. FOODS, vol. 11, pp. 580-580, ISSN:2304-8158 DOI  

  Micheli L.; Lucarini E.; Toti A.; Ferrara V.; Ciampi C.; Parisio C.; Bartolucci G.; Di Cesare Mannelli L.; Ghelardini C. (2022). Effects of Ultramicronized N-Palmitoylethanolamine Supplementation on Tramadol and Oxycodone Analgesia and Tolerance Prevention. PHARMACEUTICS, vol. 14, pp. 403-403, ISSN:1999-4923 DOI  

  Micheli, Laura; Maramai, Samuele; Toti, Alessandra; Ferrara, Valentina; Ciampi, Clara; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2022). Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 0-0, ISSN:1422-0067 DOI  

  Micheli, Laura; Toti, Alessandra; Lucarini, Elena; Ferrara, Valentina; Ciampi, Clara; Olivero, Guendalina; Pittaluga, Anna; Mattoli, Luisa; Pelucchini, Caroline; Burico, Michela; Lucci, Jacopo; Carrino, Donatello; Pacini, Alessandra; Pallanti, Stefano; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2022). Efficacy of a vegetal mixture composed of Zingiber officinale, Echinacea purpurea, and Centella asiatica in a mouse model of neuroinflammation: In vivo and ex vivo analysis. FRONTIERS IN NUTRITION, vol. 9, pp. 0-0, ISSN:2296-861X DOI  

  Lucarini E., Nocentini A., Bonardi A., Chiaramonte N., Parisio C., Micheli L., Toti A., Ferrara V., Carrino D., Pacini A., Romanelli M.N., Supuran C.T., Ghelardini C., Di Cesare Mannelli L. (2021). Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats. CELLS, vol. 10, pp. 2540-2555, ISSN:2073-4409 DOI  

  Micheli L., Parisio C., Lucarini E., Vona A., Toti A., Pacini A., Mello T., Boccella S., Ricciardi F., Maione S., Graziani G., Lacal P.M., Failli P., Ghelardini C., Di Cesare Mannelli L. (2021). VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, pp. 1-19, ISSN:1756-9966 DOI  

  Toti A.; Santi A.; Pardella E.; Nesi I.; Tomasini R.; Mello T.; Paoli P.; Caselli A.; Cirri P. (2021). Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1. JOURNAL OF CELL COMMUNICATION AND SIGNALING, vol. 15, pp. 405-419, ISSN:1873-9601 DOI   Accesso ONLINE all'editore

  Angeli A.; Pinteala M.; Maier S.S.; Toti A.; Di Cesare Mannelli L.; Ghelardini C.; Selleri S.; Carta F.; Supuran C.T. (2021). Tellurides bearing benzensulfonamide as carbonic anhydrase inhibitors with potent antitumor activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 45, pp. 0-0, ISSN:0960-894X DOI  

  Lucrezia Caselli, Marco Mendozza, Beatrice Muzzi, Alessandra Toti, Costanza Montis, Tommaso Mello, Lorenzo Di Cesare Mannelli, Carla Ghelardini,Claudio Sangregorio, Debora Berti (2021). Lipid Cubic Mesophases Combined with Superparamagnetic Iron Oxide Nanoparticles: A Hybrid Multifunctional Platform with Tunable Magnetic Properties for Nanomedical Applications. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 9268-9268, ISSN:1661-6596 DOI  

  Lucarini E.; Seguella L.; Vincenzi M.; Parisio C.; Micheli L.; Toti A.; Corpetti C.; Del Re A.; Squillace S.; Maftei D.; Lattanzi R.; Ghelardini C.; Di Cesare Mannelli L.; Esposito G. (2021). Role of enteric glia as bridging element between gut inflammation and visceral pain consolidation during acute colitis in rats. BIOMEDICINES, vol. 9, pp. 1671-1671, ISSN:2227-9059 DOI  

  Micheli L., Rajagopalan R., Lucarini E., Toti A., Parisio C., Carrino D., Pacini A., Ghelardini C., Rajagopalan P., Di Cesare Mannelli L. (2021). Pain Relieving and Neuroprotective Effects of Non-opioid Compound, DDD-028, in the Rat Model of Paclitaxel-Induced Neuropathy. NEUROTHERAPEUTICS, pp. 1-13, ISSN:1933-7213 DOI  

  Di Cesare Mannelli L.; Micheli L.; Lucarini E.; Parisio C.; Toti A.; Tenci B.; Zanardelli M.; Branca J.J.V.; Pacini A.; Ghelardini C. (2020). Effects of the combination of β-hydroxy-β-methyl butyrate and R(+) lipoic acid in a cellular model of sarcopenia. MOLECULES, vol. 25, pp. 1-18, ISSN:1420-3049 DOI  

  Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Carmen Parisio, Alessandra Toti, Bruno Fiorentino, Maria Adele Rigamonti, Laura Calosi, and Carla Ghelardini (2020). Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study. FRONTIERS IN PHARMACOLOGY, pp. 0-0, ISSN:1663-9812 DOI  

  Parisio C.; Lucarini E.; Micheli L.; Toti A.; Khatib M.; Mulinacci N.; Calosi L.; Bani D.; Mannelli L.D.C.; Ghelardini C. (2020). Pomegranate mesocarp against colitis-induced visceral pain in rats: Effects of a decoction and its fractions. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1-16, ISSN:1661-6596 DOI  

  Parisio C.; Lucarini E.; Micheli L.; Toti A.; Mannelli L.D.C.; Antonini G.; Panizzi E.; Maidecchi A.; Giovagnoni E.; Lucci J.; Ghelardini C. (2020). Researching new therapeutic approaches for abdominal visceral pain treatment: Preclinical effects of an assembled system of molecules of vegetal origin. NUTRIENTS, vol. 12, pp. 0-0, ISSN:2072-6643 DOI  

  Parisio C.; Lucarini E.; Micheli L.; Toti A.; Bellumori M.; Cecchi L.; Calosi L.; Bani D.; Di Cesare Mannelli L.; Mulinacci N.; Ghelardini C. (2020). Extra virgin olive oil and related by-products (: Olea europaea L.) as natural sources of phenolic compounds for abdominal pain relief in gastrointestinal disorders in rats. FOOD & FUNCTION, vol. 11, pp. 10423-10435, ISSN:2042-6496 DOI   Accesso ONLINE all'editore