Laura DELLA CORTE

Ruolo attuale:: Professore Associato in Pensione
SSD:: BIO/14 - Farmacologia
Afferenza organizzativa:: Dipartimento di Farmacologia preclinica e clinica 'M. Aiazzi Mancini'

Recapiti

laura.dellacorte(AT)unifi.it

Ulteriori Recapiti

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Laura DELLA CORTE

Orario di ricevimento (aggiornato al 21/04/2025)

Dal pensionamento nel 2011, nessun orario di ricevimento

Laura DELLA CORTE

Biografia

Laura Della Corte è un Professore Associato di Farmacologia in pensione dal 2011.

In attività, ha svolto corsi di insegnamento di Farmacologia per studenti della Facoltà di Medicina e della Facoltà di Farmacia. LDC ha inoltre condotto ricerche principalmente nel settore delle Neuroscienze. Ha trascorso, per motivi di studio e ricerca, molti anni all’estero: in Inghilterra, a Cambridge (1970-72, 7 mesi/anno 1973-1975), dove ha conseguito il PhD in Farmacologia, e ad Oxford (1984-1985), negli USA a East Lansing (MI, 1992-93). Project Leader di un programma europeo BIOMED con 5 Università partner (1994-1997).

Dal 1989 al 2011, Responsabile delle Relazioni Internazionali per la Facoltà di Medicina, Coordinatrice di Reti Europee ERASMUS (poi SOCRATES) e TEMPUS per gli scambi di studenti e docenti, ogni anno con centinaia di studenti dei vari corsi di laurea della Facoltà di Medicina scambiati con 17 Università Partner.

Amante della montagna, negli anni dell’Università ha frequentato il CAI di Firenze ed effettuato arrampicate su roccia e ghiaccio raggiungendo l’ Aiguilles de Trélatēte, sul Monte Bianco, la cima del Gran Paradiso e le Torri del Vajolet, nelle Dolomiti, e alcune cime del massiccio del Gran Sasso. Nel ‘68 ha partecipato attivamente ai movimenti studenteschi.

Nel 1980 si è sposata con il fisico Alberto Dellafiore, nel 1981 è nato il figlio Paolo la cui figlia Sofia è nata nel 1999. Il marito è deceduto nel 2011.

Dopo il pensionamento i suoi interessi si sono spostati dalla scienza all’arte, alla storia e alle memorie di famiglia. Nell’ambito di queste aree di interesse ha seguito corsi all’Università dell’Età Libera (UEL), partecipato a visite guidate a Firenze e in altre città italiane, di mostre e musei, tramite l’adesione al Gruppo UEL, “Camminando e Ammirando”.

Ha frequentato un corso di restauro e rilegatura libri e restauro stampe. Attiva nel volontariato.

Recentemente, si è dedicata alle memorie di famiglia, pubblicando nel 2023, con l’Istituto Storico della Resistenza Senese e dell’Età Contemporanea (ISRSEC) il libretto “Storia di un Galantuomo, Nello Ticci, Libraio Antifascista” sulla vita del nonno, la cui libreria a Siena è stata sede di incontri clandestini di anti-fascisti e poi del Comitato di Liberazione Nazionale.

Infine, nel 2024 ha pubblicato il libro “Io e il Mondo” delle memorie che suo padre, il fisico Michele Della Corte, ha scritto per i nipoti. Un estratto riguardante l'attività clandestina in Radio CORA è stato pubblicato da Daniele Dominici sulla rivista il Colle di Galileo ("A fianco di Radio CORA: Arcetri 'resistente' nei ricordi di Michele Della Corte" (Il Colle di Galileo, vol. 4, 2, 2015, pp 7:28).

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Laura DELLA CORTE

Curriculum

CURRICULUM VITAE

NOME POSIZIONE

Della Corte, Laura Professore Associato in Pensione

ISTITUZIONE E LOCALITA' LIVELLO ANNO AREA DI STUDIO

Liceo Scientifico Diploma 1960

Università degli Studi di Firenze, IT Laurea 1964 Biologia

Università di Cambridge, UK Dottorato 1976 Farmacologia

Posizioni

1966-1983 Borsista del Consiglio Nazionale delle Ricerche Council (CNR), Dip. di Farmacologia, Università di Firenze, Firenze, IT

1970-1983 Assistente Incaricato di Farmacologia Molecolare, Dip. di Farmacologia, Università di Firenze, Firenze, IT

1983-2011 Professore Associato di Farmacologia Cellulare e Molecolare, Dip. di Farmacologia, Università di Firenze, Firenze, IT

Altre Esperienze e Appartenenza a Società Scientifiche

1964-1966 Borsa di Studio per giovani ricercatori, Università di Firenze

Dal 1966 Membro della Società Italiana di Farmacologia

1970-1971 Borsista British Council, Dip. di Farmacologia, Univ. di Cambridge, UK

1972-1975 Visitatore Borsista (28 mesi), Dip. di Farmacologia, Univ. di Cambridge, UK

Dal 1979 Membro della British Pharmacological Society

1984-1985 Borsista European Science Foundation & borsista NATO-Senior, Università di Oxford, UK

Dal 1985 Membro della European Neuroscience Association

1991-1992 Visitatore Borsista, Dip. di Neurosciense e Dip. di Farmacologia, Michigan State University, East Lansing, MI, USA

1989-1997 Coordinatore di Reti Europee ERASMUS e TEMPUS di Farmacologia, coinvolgendo 17 università partner europee (Firenze, Siena, Dublino TCD e Dublino UCD, Barcellona, Madrid, Oxford, Cambridge, Vienna, Karolinska, Helsinki, Kuopio, Riga, Sofia, Dip. di Farmacologia e Dip di Fisiologia, Varna e Budapest)

Dal 1996 Membro del Editorial Board of Neuroscience.

1996-1997 Organizzatrice di due International postgraduate Intensive Courses: “Modern Quantitative Techniques in Neurobiology: Advantages and Pitfalls”, Londra, UK, 14-17 Aprile 1996, e “Biochemical Pharmacological Techniques: Theoretical & Experimental Aspects”, Londra, UK, 6-16 Aprile 1997.

1994-1997 Project Leader della European BIOMED Concerted Action: "Eurotaurine: Regulation and Function of Taurine in the Mammalian Central Nervous System" (5 Università partner: Firenze, Siena, Dublino TCD, Dublino UCD e Barcellona).

Since 1996 Italian Representative nel Management Committee delle European COST Actions: COST D8 “Chemistry of Metals in Medicine” (1996-2001), COST D13 “New Molecules towards Human Health Care” (1998-2004), COST D28 “Natural Products as a Source for Discovery, Synthesis and Application of New Pharmaceuticals” (2001-2006), COST D34 "Molecular targeting and drug design in neurological and bacterial diseases” (2005-2010) and Vice chairman of COST CM1103 “Structure-based drug design for diagnosis and treatment of neurological diseases: dissecting and modulating complex function in the monoaminergic systems of the brain" (2011-2015).

1997-2011 Responsabile delle Relazioni Internazionali, Facoltà di Medicina e Chirurgia, Univ. di Firenze, Firenze, IT

Since 1998 Membro della: American Society for Neuroscience e della International Society for Neurochemistry

1999 Chairman del “International Symposium Taurine ‘99” tenutosi alla Certosa di Pontignano, Siena, IT, 4-8 Agosto 1999.

2002 Chairman del COST D13 Workshop “New Molecules towards Human Health Care” tenutosi al Convitto della Calza, Firenze, IT, 17-21 Aprile 2002.

2010 Chairman del COST D34 Final Meeting “Structure-based drug design for diagnosis and treatment of neurological diseases”, tenutosi al Convitto della Calza, Firenze, IT, 13-16 Ottobre 2010.

Distinzioni

2005 FBPharmacolS (Invited Fellow of the British Pharmacological Society)

Publicazioni

Bianchi, L., Sharp T., Bolam J.P. & Della Corte L. (1994) The effect of kainic acid on the release of GABA in rat neostriatum and substantia nigra. Neuroreport, 5, 1233-1236.

Corsi C., Pazzagli M., Bianchi L., Della Corte L., Pepeu G. & Pedata F.(1997) Excitatory amino acids and GABA release from the striatum of aging rats: adenosine modulation. Neurobiol Aging, 18, 243-250.

Bianchi L., Colivicchi M.A. Bolam J.P. and Della Corte L. (1998) The release of amino acids from rat neostriatum and substantia nigra in vivo: a dual probe microdialysis study. Neuroscience 87, 171-180.

Bianchi L., Della Corte L. & Tipton K.F. (1999) Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices. J. Chromatogr. B, 723, 47-59.

Frosini M., Sesti C., Palmi M., Valoti M., Fusi F., Mantovani P., Bianchi L., Della Corte L. & Sgaragli G.P. (2000) Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279, R2095-R2103.

Hayes J., Tipton K.F., Bianchi L. & Della Corte L. (2001) Complexities in the neurotoxic actions of 6-hydroxydopamine in relation to the cytoprotective properties of taurine. Brain Res. Bull. 55, 239-245.

Della Corte L., Crichton R.R., Duburs G., Nolan K., Tipton K.F., Tirzitis G. & Ward R.J, (2002) The use of taurine analogues to investigate taurine functions and their potential therapeutic applications. Amino Acids 23, 367-379.

Galeffi G., Bianchi L., Bolam J.P. & Della Corte L. (2003) The effect of 6-hydroxydopamine lesions on the release of amino acids in the direct and indirect pathways of the basal ganglia: a dual probe microdialysis. Eur J. Neurosci. 18, 856-868.

Bianchi L., Ballini C., Colivicchi M.A., Della Corte L., Giovannini M.G., & Pepeu G. (2003) Investigations on aspartate, glutamate and GABA release from ventral hippocampus during repeated exploratory activity in the rat. Neurochem. Res. 28, 565-573.

Melani A., De Micheli E., Pinna G., Alfieri A., Della Corte L. & Pedata F. (2003) Adenosine extracellular levels in human brain gliomas: an intraoperative microdialysis study. Neurosci. Lett. 346, 93-96.

Bianchi, L., De Micheli, E., Bricolo A., Fattori, M., Venturi, C., Pedata, F., Tipton, K.F. & Della Corte, L. (2004) Extracellular levels of amino acids and choline in human high grade gliomas: an intraoperative microdialysis study. Neurochem. Res. 29, 325-334.

Rosi S., Giovannini M.G., Lestage P.J., Munoz C., Della Corte L., & Pepeu G. (2004) S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rats. Neurosci. Lett. 361, 120-123.

Colivicchi M.A., Raimondi L., Bianchi L., Tipton K.F., Pirisino R. & Della Corte L. (2004) Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes. Eur. J. Pharmacol. 495, 209-215.

Marti M., Manzalini M., Fantin M., Bianchi C., Della Corte L. & Morari M. (2005) Striatal glutamate release evoked in vivo by NMDA is dependent upon ongoing neuronal activity in the substantia nigra, endogenous striatal substance P and dopamine. J. Neurochem. 93, 195–205.

Mlinar B., Tatini F., Ballini C., Nencioni S., Della Corte L. & Corradetti R. (2005) Differential autoinhibition of 5-hydroxytryptamine neurons by 5-hydroxytryptamine in the dorsal raphe nucleus. NeuroReport 16, 1351-1355.

Giovannini M.G., Pazzagli M., Malmberg-Aiello P., Della Corte L., Rakovska A.D., Cerbai E., Casamenti F. & Pepeu G. (2005) Inhibition of acetylcholine-induced activation of extracellular regulated protein kinase prevents the encoding of an inhibitory avoidance response in the rat. Neuroscience 136, 15-32. (IF=3.215)

Cenni G., Blandina P., Mackie K., Nosi D., Formigli L., Giannoni P., Ballini C., Della Corte, L., Mannaioni M.F. & Passani B. (2006) Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain.Eur. J. Neurosci. 24, 1633-1644.

Mucignat-Carretta C., Colivicchi M.A., Fattori M., Ballini C., Bianchi L., Gabai G., Cavaggioni A., Della Corte L. (2006) Species-specific chemosignals evoke delayed excitation of the vomeronasal amygdala in freely-moving female rats. J. Neurochem. 99, 881-891.

Freinbichler W, Colivicchi MA, Fattori M, Ballini C, Tipton KF, Linert W, Della Corte L. (2008) Validation of a robust and sensitive method for detecting hydroxyl radical formation together with evoked neurotransmitter release in brain microdialysis. J. Neurochem. 105, 738-749.

Freinbichler W., Bianchi L., Colivicchi M.A., Ballini .C, Tipton K.F., Linert W., Della Corte L. (2008) The detection of hydroxyl radicals in vivo. J. Inorg. Biochem. 102, 1329-1333.

Ballini C., Della Corte L., Pazzagli M., Colivicchi M.A., Pepeu G., Tipton K.F. and Giovannini M.G. (2008) Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat. J. Neurochem. 106, 1035-1043.

Petkova-Kirova P, Rakovska A, Zaekova G, Ballini C, Della Corte L, Radomirov R, Vágvölgyi A. (2008) Stimulation by neurotensin of dopamine and 5-hydroxytryptamine (5-HT) release from rat prefrontal cortex: Possible role of NTR1 receptors in neuropsychiatric disorders. Neurochem Int. 53, 355-61.

Petkova-Kirova P, Rakovska A, Della Corte L, Zaekova G, Radomirov R, Mayer A. (2008) Neurotensin modulation of acetylcholine, GABA, and aspartate release from rat prefrontal cortex studied in vivo with microdialysis. Brain Res Bull. 77, 129-35.

Freinbichler W., Tipton K.F., Della Corte L. and Linert W. (2009) Mechanistic aspects of the Fenton reaction under conditions approximated to the extracellular fluid. J. Inorg. Biochem. 103, 28-34.

Ward RJ, Colivicchi MA, Allen R, Schol F, Lallemand F, De Witte P, Ballini C, Della Corte L, Dexter D (2009) Neuro-inflammation induced in the hippocampus of ‘binge drinking’ rats may be mediated by elevated extracellular glutamate content. J. Neurochem. 111, 1119-1128.

Giannoni P, Medhurst AD, Passani M-B, Giovannini MG, Ballini C, Della Corte L, Blandina P. (2010) Regional differential effects of the novel histamine H₃ receptor antagonist GSK189254 on histamine release in the CNS of freely moving rats. J. Pharmacol. Exp. Ther. 332, 164-172.

Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano PF, Tofaris GK, Goedert M, Spillantini MG (2010) SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease. Brain 133, 2032–2044.

Ward RJ, Crichton RR, Taylor DL, Della Corte L, Srai SK, Dexter DT (2011) Iron and the immune system. J Neural Transm. 118, 315-328.

Freinbichler W, Colivicchi Maria A, Stefanini C, Ballini C, Bianchi L, Weinberger P, Linert W, Tipton KF and Della Corte L (2011)Highly reactive oxygen species: Detection, Formation and possible functions. Cell Mol Life Sci 68, 2067-2079.

Ward RJ, Lallemand F, de Witte P, Crichton RR, Piette J, Tipton K, Hemmings K, Pitard A, Page M, Della Corte L, Taylor D, Dexter D. (2011) Anti-inflammatory actions of a taurine analogue, ethane b-sultam, in phagocytic cells, in vivo and in vitro. Biochem Pharmac 81, 743-751.

Dexter DT, Statton SA, Whitmore C, Freinbichler W, Weinberger P, Tipton KF, Della Corte L, Ward RJ, Crichton RR. (2011) Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration. J Neural Transm 118,223-231.

Colivicchi MA, Stefanini C, Freinbichler W, Ballini C, Bianchi L, Tipton KF, Della Corte L (2013) Monitoring Extracellular Amino Acid Neurotransmitters and hROS by In Vivo Microdialysis in Rats: A Practical Approach, in: G Di Giovanni and V Di Matteo (eds.), Microdialysis Techniques in Neuroscience, Neuromethods, 75, 225-247, Springer Science + Business Media, LLC.

Di Giovanni G, García I, Colangeli R, Pierucci M, Rivadulla ML, Soriano E, Chioua M, Della Corte L, Yáñez M, De Deurwaerdère P, Fall Y, Marco-Contelles J.(2014) N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties. CNS Neurosci Ther 20, 633-640.

Bolea I, Colivicchi MA, Ballini C, Marco-Contelles J, Tipton KF, Unzeta M, Della Corte L. (2014) Neuroprotective effects of the MAO-B inhibitor, PF9601N, in an in vivo model of excitotoxicity. CNS Neurosci Ther 20, 641-650.

Kelly JA, Boyle NT, Cole N, Slator GR, Colivicchi MA, Stefanini C, Gobbo OL, Scalabrino GA, Ryan SM, Elamin M, Walsh C, Vajda A, Goggin MM, Campbell M, Mash DC, O'Mara SM, Brayden DJ, Callanan JJ, Tipton KF, Della Corte L, Hunter J, O'Boyle KM, Williams CH, Hardiman O. (2014) First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models. Neuropharmacology 89C, 193-203.

Misini B, FreinbichlerW, Colivicchi MA, Bisilimi K, LinertW, TiptonKF, Della Corte L. (2015) Continous monitoring of highly reactive oxygen radicals during in vivo microdialysis. J Neurosci Meth 251, 1-6.

FreinbichlerW, Misini B, Colivicchi MA, LinertW, TiptonKF, Della Corte L. (2020) The application of bathophenanthroline for the determination of free iron in parallel with hROS in microdialysis samples. J. Neurosci Meth 331, 1-6.

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Laura DELLA CORTE

Interessi

Interessi di Ricerca

1- Il ruolo della taurina nel Sistema Nervoso Centrale

2- Interzioni tra neurotrasmettitori nei gangli della basa

3- Ruolo della neurotrasmissione amino acidergica nell'apprendimento e nella memoria.

4- Ruolo della neurotrasmissione amino acidergica nella comunicazione ferormonale.

5- Effetti neuroprotettivi del MAO-B inibitore, PF601N, in un modello in vivo di neurotossicità.

6- Tossicità e metabolismo degli additivi alimentari BHA e BHT nei roditori.

Laura DELLA CORTE

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

R.J. Ward; R.R. Crichton; D.L. Taylor; L. Della Corte; S.K. Srai; D.T. Dexter (2011). Iron and the immune system. JOURNAL OF NEURAL TRANSMISSION, vol. 118, pp. 315-328, ISSN:1435-1463 DOI

W. Freinbichler; M.A. Colivicchi; C. Stefanini; L. Bianchi; C. Ballini; B. Misini; P. Weinberger; W. Linert; D. Vareslija; K.F. Tipton; L. Della Corte (2011). Highly reactive oxygen species: detection, formation and possible functions. CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 68, pp. 2067-2079, ISSN:1420-9071 DOI

R.J. Ward; F. Lallemand; P. de Witte; R.R. Crichton; J. Piette; K.F. Tipton; K. Hemmings; A. Pitard; M. Page; L. Della Corte; D. Taylor; D.T. Dexter (2011). Anti-inflammatory actions of a taurine analogue, ethane β-sultam, in phagocytic cells, in vivo and in vitro. BIOCHEMICAL PHARMACOLOGY, vol. 81, pp. 743-751, ISSN:0006-2952 DOI

D.T. Dexter; S.A. Statton; C. Whitmore; W. Freinbichler; P. Weinberger; K.F. Tipton; L. Della Corte; R.J. Ward; R.R. Crichton (2011). Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration.. JOURNAL OF NEURAL TRANSMISSION, vol. 118, pp. 223-231, ISSN:0300-9564 DOI

P. Garcia-Reitbo; O. Anichtchik; A. Bellucci; M. Iovino; C. Ballini; E. Fineberg; B. Ghetti; L. Della Corte; P.F. Spano; G.K. Tofaris; M. Goedert; M.G. Spillantini (2010). SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease.. BRAIN, vol. 133, pp. 2032-2044, ISSN:0006-8950 DOI

P. Giannoni; A.D. Medhurst; M.B. Passani; M.G. Giovannini; C. Ballini; L. Della Corte; P. Blandina (2010). Regional differential effects of the novel histamine H3 receptor antagonist GSK189254 on histamine release in the CNS of freely moving rats. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 332, pp. 164-172, ISSN:1521-0103 DOI Accesso ONLINE all'editore

R.J. Ward; M.A. Colivicchi; R. Allen; F. Schol; F. Lallemand; P. De Witte; C. Ballini; L. Della Corte; D. Dexter (2009). Neuro-inflammation induced in the hippocampus of ‘binge drinking’ rats may be mediated by elevated extracellular glutamate content.. JOURNAL OF NEUROCHEMISTRY, vol. 111, pp. 1119-1128, ISSN:0022-3042 DOI

W. Freinbichler; K. F. Tipton; L. Della Corte; W. Linert (2009). Mechanistic aspects of the Fenton reaction under conditions approximated to the extracellular fluid. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 103, pp. 28-34, ISSN:0162-0134

P. Petkova-Kirova; A. Rakovska; L. Della Corte; G. Zaekova; R. Radomirov; A. Mayer (2008). Neurotensin modulation of acetylcholine, GABA, and aspartate release from rat prefrontal cortex studied in vivo with microdialysis. BRAIN RESEARCH BULLETIN, vol. 77, pp. 129-135, ISSN:0361-9230

W. Freinbichler; M. A. Colivicchi; M. Fattori; C. Ballini; K. F. Tipton; W. Linert; L. Della Corte (2008). Validation of a robust and sensitive method for detecting hydroxyl radical formation together with evoked neurotransmitter release in brain microdialysis. JOURNAL OF NEUROCHEMISTRY, vol. 105, pp. 738-749, ISSN:0022-3042

Ballini C; Della Corte L; Pazzagli M; Colivicchi MA; Pepeu G; Tipton KF; Giovannini MG. (2008). Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat.. JOURNAL OF NEUROCHEMISTRY, vol. 106, pp. 1035-1043, ISSN:0022-3042 DOI

W. Freinbichler; L. Bianchi; M. A. Colivicchi; C. Ballini; K. F. Tipton; W. Linert; L. Della Corte (2008). The detection of hydroxyl radicals in vivo. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 102, pp. 1329-1333, ISSN:0162-0134

P. Petkova-Kirova; A. Rakovska; G. Zaekova; C. Ballini; L. Della Corte; R. Radomirov; A. Vagvolgyi (2008). Stimulation by neurotensin of dopamine and 5-hydroxytryptamine (5-HT) release from rat prefrontal cortex: Possible role of NTR1 receptors in neuropsychiatric disorders. NEUROCHEMISTRY INTERNATIONAL, vol. 53, pp. 355-361, ISSN:0197-0186

BIANCHI L; COLIVICCHI MA; BALLINI C; FATTORI M; VENTURI C; GIOVANNINI MG; HEALY J; TIPTON KF; L. DELLA CORTE (2006). Taurine, taurine analogues, and taurine functions: overview. In: Oja SS, Saransaari P. Advances in Experimental Medicine and Biology, pp. 443-448 Finnish Physiological Society.

M. FATTORI; G. GABAI; A. CAVAGGIONI; L. DELLA CORTE; L. BIANCHI; C. BALLINI; M. COLIVICCHI; C. MUCIGNAT (2006). Species-specific chemosignals evoke delayed excitation of the vomeronasal amygdala in freely-moving female rats.. JOURNAL OF NEUROCHEMISTRY, vol. 99, pp. 881-891, ISSN:0022-3042

MG GIOVANNINI; M PAZZAGLI; P MALMBERG-AIELLO; L DELLA CORTE; AD RAKOVSKA; F CERBAI; F CASAMENTI; G PEPEU. (2005). Inhibition of acetylcholine-induced activation of extracellular regulated protein kinase prevents the encoding of an inhibitory avoidance response in the rat. NEUROSCIENCE, vol. 136, pp. 15-32, ISSN:0306-4522 DOI

MARTI M; MANZALINI M; FANTIN M; BIANCHI C; DELLA CORTE L; MORARI M (2005). Striatal glutamate release evoked in vivo by NMDA is dependent upon ongoing neuronal activity in the substantia nigra, endogenous striatal substance P and dopamine. JOURNAL OF NEUROCHEMISTRY, vol. 93, pp. 195-205, ISSN:0022-3042

MLINAR B; TATINI F; BALLINI C; NENCIONI S; DELLA CORTE L; CORRADETTI R. (2005). Differential autoinhibition of 5-hydroxytryptamine neurons by 5-hydroxytryptamine in the dorsal raphe nucleus.. NEUROREPORT, vol. 16, pp. 1351-1355, ISSN:0959-4965

ROSI S.; M. GIOVANNINI; LESTAGE PJ.; MUNOZ C.; DELLA CORTE L.; PEPEU G. (2004). S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rats.. NEUROSCIENCE LETTERS, vol. 361, pp. 120-123, ISSN:0304-3940 DOI

L. Bianchi; E. De Micheli; A. Bricolo; C. Ballini; M. Fattori; C. Venturi; F. Pedata; K. F. Tipton; L. Della Corte (2004). Extracellular levels of amino acids and choline in human high grade gliomas: An intraoperative microdialysis study. NEUROCHEMICAL RESEARCH, vol. 29, pp. 325-334, ISSN:0364-3190

M. A. Colivicchi; L. Raimondi; L. Bianchi; K. F. Tipton; R. Pirisino; L. Della Corte (2004). Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 495, pp. 209-215, ISSN:0014-2999

Melani A; De Micheli E; Pinna G; Alfieri A; Della Corte L; Pedata F. (2003). Adenosine extracellular levels in human brain gliomas: an intraoperative microdialysis study.. NEUROSCIENCE LETTERS, vol. 346, pp. 93-96, ISSN:0304-3940

GALEFFI F.; BIANCHI L.; BOLAM J.P.; DELLA CORTE L. (2003). The effect of 6-hydroxydopamine lesions on the release of amino acids in the direct and indirect pathways of the basal ganglia: a dual probe microdialysis.. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 18, pp. 856-868, ISSN:0953-816X

BIANCHI L; BALLINI C; COLIVICCHI MA; DELLA CORTE L; GIOVANNINI MG; PEPEU G. (2003). Investigations on acetylcholine, aspartate, glutamate and GABA extracellular levels from ventral hippocampus during repeated exploratory activity in the rat. NEUROCHEMICAL RESEARCH, vol. 28, pp. 565-573, ISSN:0364-3190 DOI

M.G. Giovannini; M.Pazzagli; P.Malberg-Aiello; L.Della Corte; C.Ballini; G.Pepeu (2003). AN INIBITORY AVOIDANCE TASK INCREASES ACETYLCHOLINE AND GABA RELEASE AND ACTIVATES ERKS IN THE MEDIAL PREFRONTAL CORTEX OF THE RAT.. In: 33rd Annual Meeting of the Society for Neuroscience, Society forNeuroscience, pp. Program No. 836.7.-Program No. 836.7..

DELLA CORTE L.; CRICHTON RR; DUBURS G; NOLAN K; TIPTON KF; TIRZITIS G; WARD RJ (2002). The use of taurine analogues to investigate taurine functions and their potential therapeutic applications.. AMINO ACIDS, vol. 23, pp. 367-379, ISSN:0939-4451

J. Hayes; K. F. Tipton; L. Bianchi; L. Della Corte (2001). Complexities in the neurotoxic actions of 6-hydroxydopamine in relation to the cytoprotective properties of taurine. BRAIN RESEARCH BULLETIN, vol. 55, pp. 239-245, ISSN:0361-9230

M.G. GIOVANNINI; A. RAKOVSKA; R.S. BENTON; L. BIANCHI; L. DELLA CORTE; G. PEPEU (2001). ACh and GABA release from the cortex and hippocampus of the rat during novelty and habituation. BRITISH JOURNAL OF PHARMACOLOGY, vol. 133, pp. 174-174, ISSN:0007-1188

G. GUASPRINI; L. BIANCHI; M.G. GIOVANNINI; G. PEPEU; L. DELLA CORTE (2001). Extracellular concentrations of acetylcholine, GABA, glutamate and aspartate in the rat ventral hippocampus during exploratory activity in an open field.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 133, pp. 76-76, ISSN:0007-1188

E. De Micheli; G. Pinna; A. Alfieri; G. Caramia; L. Bianchi; M. A. Colivicchi; L. Della Corte; A. Bricolo (2000). Post-operative monitoring of cortical taurine in patients with subarachnoid hemorrhage: A microdialysis study. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 595-603, ISSN:0065-2598

M. Frosini; C. Sesti; M. Palmi; M. Valoti; F. Fusi; P. Mantovani; L. Bianchi; L. Della Corte; G. Sgaragli (2000). The possible role of taurine and GABA as endogenous cryogens in the rabbit - Changes in CSF levels in heat-stress. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 335-344, ISSN:0065-2598

E. De Micheli; A. Alfieri; G. Pinna; L. Bianchi; M. A. Colivicchi; A. Melani; F. Pedata; L. Della Corte; A. Bricolo (2000). Extracellular levels of taurine in tumoral, peritumoral and normal brain tissue in patients with malignant glioma: An intraoperative microdialysis study. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 621-625, ISSN:0065-2598

FROSINI M; SESTI C; PALMI M; VALOTI M; FUSI F; MANTOVANI P; BIANCHI L; L. DELLA CORTE; GP SGARAGLI (2000). Heat-stress induced hyperthermia alters CSF osmolality and composition in conscious rabbits.. AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, vol. 279, pp. R2095-R2103, ISSN:0363-6119

M. Palmi; G. T. Youmbi; G. Sgaragli; A. Meini; A. Benocci; F. Fusi; M. Frosini; L. Della Corte; G. Davey; K. F. Tipton (2000). The mitochondrial permeability transition and taurine. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 87-96, ISSN:0065-2598

S. Capodarca; C. M. Cunningham; P. Bartolini; K. F. Tipton; L. Della Corte; L. Bianchi; R. J. Ward; A. Dachour; E. Quertemont; F. Lallemand; P. De Witte (2000). Effects of ethanol and glutamate agonist infusion on the outflow of sulphoacetaldehyde - Microdialysis studies. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 297-304, ISSN:0065-2598

L. Bianchi; M. A. Colivicchi; M. Frosini; M. Palmi; L. Della Corte (2000). The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 483, pp. 293-296, ISSN:0065-2598

Pinna G.; Pedata F.; Bianchi L.; Alfieri A.; De Micheli E.; Melani A.; Della Corte L.; Colivicchi M.A. (1999). Amino acids, adenosine choline extracellular levels as possible markers in human brain gliomas: an intraoperative microdialysis study.. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol. 37, pp. S222-S222, ISSN:1434-6621

BIANCHI L; L. DELLA CORTE; TIPTON KF (1999). Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices.. JOURNAL OF CHROMATOGRAPHY B. BIOMEDICAL APPLICATIONS, vol. 723, pp. 47-59, ISSN:0378-4347, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

Bianchi L.; Melani A.; Colivicchi A.; De Micheli E.; Alfieri A.; Pinna G.; Pedata F.; Della Corte L. (1999). Intraoperative microdialysis in human brain gliomas: amino acids, adenosine and choline extracellular levels.. PHARMACOLOGICAL RESEARCH, vol. 39 (suppl), pp. 105-105, ISSN:1043-6618

L BIANCHI; MA COLIVICCHI; JP BOLAM; L DELLA CORTE (1998). The release of amino acids from rat neostriatum and substantia nigra in vivo: a dual microdialysis probe analysis. NEUROSCIENCE, vol. 87, pp. 171-180, ISSN:0306-4522, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

M.G. GIOVANNINI; A. RAKOVSKA; L. DELLA CORTE; L. BIANCHI; G. PEPEU (1998). Activation of non-NMDA receptors stimulates acethylcholine and GABA release from dorsal hippocampus: a microdialysis study in the rat. NEUROSCIENCE LETTERS, vol. 243, pp. 152-156, ISSN:0304-3940 DOI

A RAKOVSKA; MG GIOVANNINI; L DELLA CORTE; R KALFIN; L BIANCHI; G PEPEU (1998). Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study.. NEUROCHEMISTRY INTERNATIONAL, vol. 33, pp. 335-340, ISSN:0197-0186 DOI

C. CORSI; M. PAZZAGLI; L. BIANCHI; L. DELLA CORTE; G. PEPEU; F. PEDATA (1997). In vivo amino acid release from the striatum of aging rats: adenosine modulation. NEUROBIOLOGY OF AGING, vol. 18, pp. 243-250, ISSN:0197-4580

C CORSI; M PAZZAGLI; L BIANCHI; L. DELLA CORTE; G PEPEU (1997). Excitatory amino acids and GABA release from the striatum of aging rats: adenosine modulation. NEUROBIOLOGY OF AGING, vol. 18, pp. 243-250, ISSN:0197-4580, Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680:

L. Bianchi; M. A. Colivicchi; L. Della Corte; M. Valoti; G. P. Sgaragli; P. Bechi (1997). Measurement of synthetic phenolic antioxidants in human tissues by high-performance liquid chromatography with coulometric electrochemical detection. JOURNAL OF CHROMATOGRAPHY B. BIOMEDICAL SCIENCES AND APPLICATIONS, vol. 694, pp. 359-365, ISSN:1387-2273

A. D. RAKOVSKA; M.G. GIOVANNINI; L. DELLA CORTE; L. BIANCHI; G. PEPEU (1996). Excitatory amino acid, GABA and acetylcholine release from the rat hippocampus. Neurotensin modulation: an in vivo microdialysis study.. In: International School on Strategies in Drug Design and Development. Sozopol, Sozopol, Bulgaria, October 6-12, 1996, pp. 46-46.

G. P. SGARAGLI; M. VALOTI; M. PALMI; M. FROSINI; M. G. GIOVANNINI; L. BIANCHI; L. DELLA CORTE (1995). Rat-Tissue Concentrations Of Chlorimipramine, Chlorpromazine And Their N-Demethylated Metabolites After A Single Oral Dose Of The Parent Compounds. JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 47, pp. 782-790, ISSN:0022-3573

Pedata F.; Corsi C.; Pazzagli M.; Bianchi L.; Della Corte L.; Pepeu G. (1995). Regulation between adenosine and excitatory aminoacids release "in vivo" in adult and old freely moving rats.. PHARMACOLOGICAL RESEARCH, vol. 31, pp. 167-167, ISSN:1043-6618

L BIANCHI; T SHARP; JP BOLAM; L. DELLA CORTE (1994). The effect of kainic acid on the release of GABA in rat neostriatum and substantia nigra. NEUROREPORT, vol. 5, pp. 1233-1236, ISSN:0959-4965, Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320:

L. DELLA CORTE; M. VALOTI; M. PALMI; M. G. GIOVANNINI; G. P. SGARAGLI (1993). Pharmacokinetics Of Chlorimipramine, Chlorpromazine And Their N-Dealkylated Metabolites In Plasma Of Healthy-Volunteers After A Single Oral Dose Of The Parent Compounds. JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 45, pp. 825-829, ISSN:0022-3573

M. VALOTI; M. PALMI; L. DELLA CORTE; M. NARDINI; P. CORTI; G. P. SGARAGLI (1992). Dehalogenation And N-Dealkylation Of Chlorpromazine As Revealed By Plasma-Concentrations Of Metabolites In A Population Of Chronically Medicated Schizophrenics. METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, vol. 14, pp. 445-450, ISSN:0379-0355

L. DELLA CORTE; J. P. BOLAM; D. J. CLARKE; D. M. PARRY; A. D. SMITH (1990). Sites Of [H-3] Taurine Uptake In The Rat Substantia-Nigra In Relation To The Release Of Taurine From The Striatonigral Pathway. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 2, pp. 50-61, ISSN:0953-816X

Sgaragli GP;L. Della Corte; M.G. Giovannini;Ninci R;Franco C;Nardini M (1984). Microdetermination of some tricyclic psychotropic drugs and their N-demethylated metabolites by GLC with nitrogen-phosphorus sensitive detection. BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE, vol. 60, pp. 1757-1763, ISSN:0037-8771

Della Corte L;Giovannini MG;Sgaragli GP (1984). Microanalytical GCMS method for the assay of the food additive 2-t-butyl-4-methoxyphenol (BHA) in plasma.. BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE, vol. 60, pp. 1765-1769, ISSN:0037-8771

L. DELLA CORTE; M.G. GIOVANNINI; G.P. SGARAGLI (1984). Distribution and metabolism of 2-t-butyl-4-methoxyphenol in the everted rat gut preparation. ARCHIVES OF TOXICOLOGY, vol. 7, pp. 307-310, ISSN:0340-5761

A. GUARNA; L. DELLA CORTE; M.G. GIOVANNINI; F. DE SARLO; G.SGARAGLI (1983). 2,2'-Dihydroxy-3,3'-di-t-butyl-5,5'-dimethoxydiphenyl, a New Metabolite of 2-t-Butyl-4-methoxyphenol in the Rat. DRUG METABOLISM AND DISPOSITION, vol. 11, pp. 581-584, ISSN:0090-9556, American Society for Pharmacology and Experimental Therapeutics:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7024, EMAIL: pstoute@aspet.org, INTERNET: http://www.aspet.org, Fax: (301)634-7099:

L. DELLA CORTE; M.G. GIOVANNINI; P. MARTINI; I. MEGAZZINI; R. PULITI; G.P. SGARAGLI; G. WONDRAK. (1981). In vivo N-dealkylation of chlorpromazine and chlorimipramine: a single-dose kinetic study in the rat. BRITISH JOURNAL OF PHARMACOLOGY, vol. 72, pp. 184-185, ISSN:0007-1188

Puliti R;Giovannini MG;Megazzini I;Della Corte L;Marconi M;Sgaragli GP (1980). Biochemical characterization of partially purified rat intestinal peroxidase (EC 1.11.1.7).. BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE, vol. 56, pp. 2530-2534, ISSN:0037-8771

M.G. Giovannini;Puliti R;Megazzini I;Della Corte L;Marconi M;Sgaragli GP (1980). Preliminary results on a purification method for intestinal peroxidase of the rat (EC 1.11.1.7).. BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE, vol. 56, pp. 2525-2529, ISSN:0037-8771

Franchi-Micheli S;Della Corte L;Puliti R;Giovannini MG;Zilletti L;Marconi M;Sgaragli GP (1980). Mechanism of action of butylhydroxyanisole (BHA) toxicity: in vivo and in vitro effects on mammalian smooth muscle. BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE, vol. 56, pp. 2521-2524, ISSN:0037-8771

G. SGARAGLI; L. DELLA CORTE; R. PULITI; F. DE SARLO; R. FRANCALANCI; A. GUARNA; P. DOLARA; M. KOMARYNSKY (1980). Oxidation of 2-tert-butyl-4-methoxyphenol (BHA) by horseradish and mammalian peroxidase systems. BIOCHEMICAL PHARMACOLOGY, vol. 29, pp. 763-769, ISSN:0006-2952, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

L.DellaCorte;A.Broadhurst;G.Sgaragli;S.Filippini;A.Heeley.H.James;C.Faravelli;A.Pazzagli (1979). Clinical response and tricyclic plasma levels during treatment with clomipramine.. BRITISH JOURNAL OF PSYCHIATRY, vol. 134, pp. 390-400, ISSN:0007-1250

Laura DELLA CORTE

Biography

Laura Della Corte, Associate Professor, retired since 2011.

During its activity, she has been a Pharmacology lecturer for Medical and Pharmacy students. She has been active in research, mainly in the field of Neuroscience. spending abroad long periods of study and research: in England, Cambridge (1970-72, 7 months/year 1973-1975) where she obtained her PhD in Pharmacology, and in Oxford (1984-1985), in USA, East Lancing (MI, 1991-1992).

Project Leader of a European BIOMED project (1994-1997) involving 5 European Universities. From 1989 to 2011, Head of the Medical Faculty International Relations, Coordinator of ERASMUS (later SOCRATES) and TEMPUS Networks for student and teacher exchanges, with hundreds of students of various degree courses of the Medical Faculty exchanged with 17 European partner Universities.

Mountain lover, during her university years, as a member of the Italian Alpine Club (CAI), she did rock and ice climbing on Aiguiles de Trélatēte (Mont Blanc), Gran Paradise, Vajolet Towers (Dolomites) and Gran Sasso Massif.

In the ’68 she was active in the student’s movement.

In 1980 she married the physicist Alberto Dellafiore, her son Paolo was born in 1981, whose daughter Sofia was born in 1999. Her husband died in 2011.

After retirement, her interests have shifted from Science to Art, History and family memories. Within these areas of interest, she attends courses at the Third Age University (UEL), and, through the UEL group “Walking and Admiring”, joining guided tours of exhibitions and Museums in Florence and other Italian cities.

She attended courses on book and print restoration and book binding.

She is active in volunteer work.

Recently, she dedicated herself to collect the family memoirs, publishing in 2023, under the Institute of Sienese Resistance and Contemporary Age (ISRSEC), the booklet “Story of a Man of Honour, Nello Ticci, Anti-fascist Book Seller”, about the life of her grandfather whose bookshop in Siena did host clandestine anti-fascist meetings and then the National Liberation Committee.

Finally, in 2024, she published the book, entitled “Myself and the World”, of the memoirs that her father, the physicist Michele Dalla Corte, had written for his grandchildren. Parts of it, related to his clandestine activity, had been published by Daniele Dominici in the Journal Il Colle di Galileo (Supporting Radio CORA: 'resistant' Arcetri, in the memoirs of Michele Della Corte, vol. 4, 2, 2015, pp 7:28).

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Laura DELLA CORTE

Curriculum

CURRICULUM VITAE

NAME POSITION TITLE

Della Corte, Laura Retired Associate Professor

INSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDY

Scientific High School Diploma 1960

Università degli Studi di Firenze, Italy BSc 1964 Biology

University of Cambridge, UK PhD 1976 Pharmacology

Positions and Employment

1966-1983 Fellow of the Italian National Research Council (CNR), Pharmacology Dept., Florence Univ., Florence, IT

1970-1983 Lecturer in Molecular Pharmacology, Pharmacology Dept., Florence Univ., Florence, IT

1983-2011 Associate Professor in Cellular and Molecular Pharmacology, Pharmacology Dept., Florence Univ., Florence, IT

Other Experience and Professional Memberships

1964-1966 Scholarship for young researchers, University of Florence

since 1969 Member of the Italian Pharmacological Society

1970-1971 British Council Scholar, Pharmacology Dept., University of Cambridge, UK

1972-1975 Visiting Fellow (28 months), Pharmacology Dept., University of Cambridge, UK

Since 1979 Member of the British Pharmacological Society

1984-1985 European Science Foundation & NATO-Senior Fellowship, University of Oxford, UK

Since 1985 Member of the European Neuroscience Association

1991-1992 Visiting Fellow, Neuroscience and Pharmacology Depts., Michigan State University, East Lansing, MI, USA

1989-1997 Coordinator of European ERASMUS and TEMPUS Networks in Pharmacology, involving 17 european partner universities (Florence, Siena, Dublin TCD and UCD, Barcelona, Madrid, Oxford, Cambridge, Vienna, Karolinska, Helsinki, Kuopio, Riga, Sofia Pharmacologi and Physiology Depts., Varna, Budapest,

Since 1996 Member of the Editorial Board of Neuroscience.

1996-1997 Organizer of two International postgraduate Intensive Courses: “Modern Quantitative Techniques in Neurobiology: Advantages and Pitfalls”, London, UK, 14-17 April 1996, and “Biochemical Pharmacological Techniques: Theoretical & Experimental Aspects”, London, UK, 6-16 Aprile 1997.

1994-1997 Project Leader of the European BIOMED Concerted Action: "Eurotaurine: Regulation and Function of Taurine in the Mammalian Central Nervous System" (5 partner Universities).

Since 1996 Italian Representative in the Management Committee of the European COST Actions: COST D8 “Chemistry of Metals in Medicine” (1996-2001), COST D13 “New Molecules towards Human Health Care” (1998-2004), COST D28 “Natural Products as a Source for Discovery, Synthesis and Application of New Pharmaceuticals” (2001-2006), COST D34 "Molecular targeting and drug design in neurological and bacterial diseases” (2005-2010) and Vice chairman of COST CM1103 “Structure-based drug design for diagnosis and treatment of neurological diseases: dissecting and modulating complex function in the monoaminergic systems of the brain" (2011-2015).

1997-2011 International Relations Officer, Faculty of Medicine and Surgery, Florence Univ., Firenze, Italy

Since 1998 Member of: American Society for Neuroscience and International Society for Neurochemistry

1999 Chairman of the “International Symposium Taurine ‘99” held in Certosa di Pontignano, Siena, Italy, 4-8 August 1999.

2002 Chairman of the COST D13 Workshop “New Molecules towards Human Health Care” held in Convitto della Calza, Firenze, Italy, 17-21 Aprile 2002.

2010 Chairman of the COST D34 Final Meeting “Structure-based drug design for diagnosis and treatment of neurological diseases”, held at Convitto della Calza, Firenze, Italy, 13-16 October 2010.

Honors

2005 FBPharmacolS (Invited Fellow of the British Pharmacological Society)

Publications