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Cristina NATIVI

Ruolo attuale:: Professore Ordinario
SSD:: CHEM-05/A - Chimica organica
Afferenza organizzativa:: Dipartimento di Chimica 'Ugo Schiff' - DICUS

Recapiti

	0554573540
	cristina.nativi(AT)unifi.it

Ulteriori Recapiti

https://sites.google.com/unifi.it/glycomore/home-page

Cristina NATIVI

Curriculum

Laureata in Chimica presso l'Universita' degli Studi di Firenze (magna cum laude).

1987-1989 Université de Lausanne con finanziamento Fond National Suisse (supervisore Prof. P. Vogel- Sintesi totale di monosaccaridi a partire da "naked sugars")

1989-1991 Universita' di Firenze - Vincitrice finanziamento CNR (progetto congiunto, finanziato IMI in collaborazione con Menarini Ricerche - Sintesi di analoghi sililati di beta-lattami)

Dicembre 1991 - Vincitrice di un posto di Ricercatore presso l'Universita' di Firenze (Facolta' di Farmacia)

1993-1994 Université de Montreal, vincitrice di un finanziamento NATO-CNR (supervisore Prof. S Hanessian- Sviluppo di una nuova metodologia di sintesi di C-glicosidi)

Novembre 2000 - Professore Associato presso l'Universita' degli Studi di Firenze (Facoltà di Farmacia)

Febbraio 2005 - Professore Ordinario presso l'Universita' degli Studi di Firenze

Principali interessi scientifici:

Sintesi stereoselettiva di glicoderivati, sintesi di derivati carboidratici solforati, inibitori di metallo proteine di membrana (MMPIs) di natura carboidratica, immunostimolanti e vaccini glicosidici, sviluppo di nuovi anti-patogeni carboidratici multivalenti. Riconoscimento molecolare di carboidrati.

Incarichi e Attività Scientifica:

E’ coautrice di piu' di 190 pubblicazioni su riviste nazionali e internazionali, di 9 capitoli-monografici, 5 brevetti, tutti approvati e di cui uno licenziato e per il quale sono in corso le prove in vivo. Oratore di numerose conferenze su invito.

E’ stata parte del Management Committee del progetto COST “ENOVA European Network on Vaccines” e co-chair della COST Action "GlycoNanoProbe". Ha fatto parte dal 2011 al 2015 del Management Committee del progetto COST “MultiGlycoNano -Multivalent Glycosystem for Nanoscience”. Co-proponente e responsabile della Comuncazione e disseminazione per la COST Action EUROSTOP, finanziata nel 2022 (strategie Europee per combattere la Resistenza Antimicrobica). Fino al 2024, coordinatore del Consiglio Direttivo del Gruppo Interdivisionale di Chimica dei Carboidrati e presidente del comitato organizzatore e scientifico del Congresso-Scuola di Chimica dei Carboidrati. Nel 2004, 2007, 2009 e 2010 ha partecipato come docente, a una scuola Europea SYNAPS sulla “Chimica dei Prodotti Naturali” nell’ambito del progetto Socrates-Erasmus. Ha fatto parte del comitato scientifico di FiorGen (Fondazione di Farmaco Genomica) e del consiglio scientifico della Da Vinci BioBank. Fa parte del Consiglio Scientifico di GiottoBiotech (spin-off dell’Universita’ degli Studi di Firenze). Nel 2022 è entrata a far parte del Consiglio Direttivo di CSAVRI (UniFi). Membro eletto per l'Italia nell'ambito della IUPAC.

Finanziamenti, Attività editoriale e Riconoscimenti

Per il 2004, 2006, 2008, 2010 e 2015 e’ stata responsabile locale di progetti PRIN finanziati dal Ministero dell’Universita’ e della Ricerca Scientifica. Responsabile scientifico del progetto “Sintesi del PNH Anchor” finanziato dall’Istituto Toscano Tumori (2008-2009) e del progetto “ A new anti-GM3 monoclonal antibody for immunotheraphy of melanoma” (2009-2010).

Nel 2012 e nel 2021 finanziata dall'Associazione AIRC per le ricerche relative allo sviluppo antigeni saccaridici per vaccini terapeutici contro il tumore (al seno triplo negativo, e adenocarcinomi).

Nel 2008 e nel 2012 finanziata dall'Universita' Italo-Francese (Progetto Galileo) con l'Universita' di Grenoble. Partecipazione a progetti EU MSCA (ENSCC finanziato nel 2023 e attivo) e coordinamento del progetto MSCA GlycoNoVi (finanziato nel 2022 e in fase di svolgimento).

E’ stato membro del direttivo della Sezione interdivisionale SCI sulla Chimica dei Carboidrati e del Direttivo SCI- Sezione Toscana. Fa parte dell’ Editorial Advisory Board della rivista Current Organic Synthesis,Vaccines and Molecules.

E’ stata presidente del Gruppo di Autovalutazione (certificazione di qualita’ CRUI) per il Corso di Studio in Chimica e Tecnologia Farmaceutiche della Facolta’ di Farmacia. Dal 2010 al 2014 ha fatto parte del Collegio dei Docenti del Dottorato in Chimica e dal 2010 e membro del Collegio dei Docenti del Dottorato Internazione in Structural Biology. Dal 2012 al 2019 e’ stata membro del collegio dell’ l'Ecole Doctorale SSBCV (Orléans-Tours). Dal 2018 al 2022 ha fatto parte del Consiglio Direttivo del Consorzio Interuniversitario CINMPIS.

Dal 2023 Membro Titolare della Divisione III della IUPAC. E’ reviewer di progetti scientifici per il MiUR, l’Israel Science Foundation e per l’Agènce de Recherche, France.

Nel 2019 è stata premiata dalla Società Chimica Italian con il Premio alla Ricerca nel settore Scienze della Vita e nel 2020 è stata selezionata come "Women in Science" dalla rivista americana ACS Omega (American Chemcal Society).

Cristina NATIVI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

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Brevetto |

Curatela | Altro

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Tesi di Dottorato

Santambrogio, Carlo; Toccafondi, Mirco; Donnici, Lorena; Pesce, Elisa; De Francesco, Raffaele; Grifantini, Renata; Ponzini, Erika; Milanesi, Francesco; Fragai, Marco; Nativi, Cristina; Roelens, Stefano; Grandori, Rita; Francesconi, Oscar (2025). Biomimetic Recognition of SARS‐CoV‐2 Receptor‐Binding Domain N‐Glycans by an Antiviral Synthetic Receptor. CHEMBIOCHEM, pp. 0-0, ISSN:1439-4227 DOI

Pesce E.; Sodini A.; Palmieri E.; Valensin S.; Tinti C.; Rossi M.; De Rosa A.; Fragai M.; Papi F.; Cordiglieri C.; Berti F.; Grifantini R.; Micoli F.; Nativi C. (2025). GMMA decorated with mucin 1 Tn/STn mimetics elicit specific antibodies response and inhibit tumor growth. NPJ VACCINES, vol. 10, pp. 1-14, ISSN:2059-0105 DOI

Priyanka Sahariah, Francesco Papi, Koi L. Merz, Olafur E. Sigurjonsson, Rikke Loiuse Meyer, Cristina Nativi (2024). Chitosan–saccharide conjugates for eradication of Pseudomonas aeruginosa biofilms. RSC APPLIED POLYMERS, vol. 2, pp. 461-472, ISSN:2755-371X DOI

Seguin-Devaux C.; Mestrovic T.; Arts J.J.; Sen Karaman D.; Nativi C.; Reichmann D.; Sahariah P.; Smani Y.; Rijo P.; Mori M. (2024). Solving the antibacterial resistance in Europe: The multipronged approach of the COST Action CA21145 EURESTOP. DRUG RESISTANCE UPDATES, vol. 74, pp. 101069-101071, ISSN:1368-7646 DOI

Corzana F.; Asin A.; Eguskiza A.; De Tomi E.; Martin-Carnicero A.; Martinez-Moral M.P.; Mangini V.; Papi F.; Breton C.; Oroz P.; Lagartera L.; Jimenez-Moreno E.; Avenoza A.; Busto J.H.; Nativi C.; Asensio J.L.; Hurtado-Guerrero R.; Peregrina J.M.; Malerba G.; Martinez A.; Fiammengo R. (2024). Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes. ANGEWANDTE CHEMIE, pp. 0-0, ISSN:1521-3773 DOI

Cristina Nativi (2023). Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 3475-3517, ISSN:1661-6596 Accesso ONLINE all'editore

Cristina Nativi (2023). The dual behavior of beta-vinylporphyrins in the presence of aka'-dioxones. NEW JOURNAL OF CHEMISTRY, vol. 47, pp. 20266-20271, ISSN:1144-0546 DOI

Cristina Nativi (2023). Early detection of tumour-associated antigens: Assessment of pointof- care electrochemical immunoassays. TRAC. TRENDS IN ANALYTICAL CHEMISTRY, vol. 160, pp. 116981-116990, ISSN:0165-9936 Accesso ONLINE all'editore

Fallarini S.; Cerofolini L.; Salobehaj M.; Rizzo D.; Gheorghita G.R.; Licciardi G.; Capialbi D.E.; Zullo V.; Sodini A.; Nativi C.; Fragai M. (2023). Site-Selective Functionalized PD-1 Mutant for a Modular Immunological Activity against Cancer Cells. BIOMACROMOLECULES, vol. 24, pp. 5428-5437, ISSN:1526-4602 DOI

Fallarini S.; Papi F.; Licciardi F.; Natali F.; Lombardi G.; Maestrelli F.; Nativi C. (2023). Niosomes as Biocompatible Scaffolds for the Multivalent Presentation of Tumor-Associated Antigens (TACAs) to the Immune System. BIOCONJUGATE CHEMISTRY, vol. 34, pp. 181-192, ISSN:1520-4812 DOI

Milanesi, Francesco; Unione, Luca; Ardá, Ana; Nativi, Cristina; Jiménez‐Barbero, Jesús; Roelens, Stefano; Francesconi, Oscar (2023). Biomimetic Tweezers for N‐Glycans: Selective Recognition of the Core GlcNAc2 Disaccharide of the Sialylglycopeptide SGP. CHEMISTRY-A EUROPEAN JOURNAL, vol. 29, pp. 0-0, ISSN:0947-6539 DOI

Oscar Francesconi, Cristina Nativi, Stefano Roelens (2022). Synthetic carbohydrate-binding agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2. ISCIENCE, vol. 25, pp. 104239-104256, ISSN:2589-0042

Francesconi, Oscar; Corzana, Francisco; Kontogianni, Georgia-Ioanna; Pesciullesi, Giorgio; Gualdani, Roberta; Supuran, Claudiu T; Angeli, Andrea; Kavasi, Rafaela Maria; Chatzinikolaidou, Maria; Nativi, Cristina (2022). Lipoyl-Based Antagonists of Transient Receptor Potential Cation A (TRPA1) Downregulate Osteosarcoma Cell Migration and Expression of Pro-Inflammatory Cytokines. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, vol. 5, pp. 0-0, ISSN:2575-9108 DOI

Francesconi O.; Ienco A.; Papi F.; Dolce M.; Catastini A.; Nativi C.; Roelens S. (2022). A Sulfonated Tweezer-Shaped Receptor Selectively Recognizes Caffeine in Water. JOURNAL OF ORGANIC CHEMISTRY, vol. 87, pp. 2662-2667, ISSN:0022-3263 DOI

Silvia Fallarini, Francesco Papi, Federico Licciardi, Francesca Natali, Grazia Lombardi, Francesca Maestrelli, Cristina Nativi (2022). Niosomes as Biocompatible Scaffolds for the Multivalent Presen-tation of Tumor Associated Antigens (TACAs) to Immune System. BIOCONJUGATE CHEMISTRY, pp. 181-192, ISSN:1520-4812

Burgalassi, Susi; Fragai, Marco; Francesconi, Oscar; Cerofolini, Linda; Monti, Daniela; Leone, Gemma; Lamponi, Stefania; Greco, Giuseppe; Magnani, Agnese; Nativi, Cristina (2022). Functionalized Hyaluronic Acid for “In Situ” Matrix Metalloproteinase Inhibition: A Bioactive Material to Treat the Dry Eye Sydrome. ACS MACRO LETTERS, pp. 1190-1194, ISSN:2161-1653 DOI

Pasquale Palladino, Francesco Papi, Maria Minunni, Cristina Nativi, Simona Scarano (2022). Structurally Constrained MUC1-Tn Mimetic Antigen as Template for Molecularly Imprinted Polymers (MIPs): A Promising Tool for Cancer Diagnostics. CHEMPLUSCHEM, vol. e202200068, pp. 1-6, ISSN:2192-6506 DOI Accesso ONLINE all'editore

Forgione, Rosa Ester; Nieto, Ferran Fabregat; Di Carluccio, Cristina; Milanesi, Francesco; Fruscella, Martina; Papi, Francesco; Nativi, Cristina; Molinaro, Antonio; Palladino, Pasquale; Scarano, Simona; Minunni, Maria; Montefiori, Marco; Civera, Monica; Sattin, Sara; Francesconi, Oscar; Marchetti, Roberta; Silipo, Alba (2022). Conformationally Constrained Sialyl Analogues as New Potential Binders of h-CD22. CHEMBIOCHEM, vol. 23, pp. 0-0, ISSN:1439-7633 DOI Accesso ONLINE all'editore

Manning, Joachim C; Baldoneschi, Veronica; Romero-Hernández, Laura L; Pichler, Katharina M; GarcÍa Caballero, Gabriel; André, Sabine; Kutzner, Tanja J; Ludwig, Anna-Kristin; Zullo, Valerio; Richichi, Barbara; Windhager, Reinhard; Kaltner, Herbert; Toegel, Stefan; Gabius, Hans-Joachim; Murphy, Paul V; Nativi, Cristina (2022). Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 75, pp. -----, ISSN:1464-3391 DOI

Francesconi O.; Milanesi F.; Nativi C.; Roelens S. (2021). A Simple Biomimetic Receptor Selectively Recognizing the GlcNAc2 Disaccharide in Water. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 60, pp. 11168-11172, ISSN:1433-7851 DOI

Leone G.; Pepi S.; Consumi M.; Lamponi S.; Fragai M.; Martinucci M.; Baldoneschi V.; Francesconi O.; Nativi C.; Magnani A. (2021). Sodium hyaluronate-g-2-((N-(6-aminohexyl)-4-methoxyphenyl)sulfonamido)-N-hydroxyacetamide with enhanced affinity towards MMP12 catalytic domain to be used as visco-supplement with increased degradation resistance. CARBOHYDRATE POLYMERS, vol. 271, pp. 0-0, ISSN:0144-8617 DOI

Francesconi O.; Milanesi F.; Nativi C.; Roelens S. (2021). Molecular Recognition of Disaccharides in Water: Preorganized Macrocyclic or Adaptive Acyclic?. CHEMISTRY-A EUROPEAN JOURNAL, vol. 27, pp. 10456-10460, ISSN:0947-6539 DOI

Sakonwan Kuhaudomlarp; Linda Cerofolini; Sabrina Santarsia; Emilie Gillon; Silvia Fallarini; Grazia Lombardi; Maxime Denis; Stefano Giuntini; Carolina Valori; Marco Fragai; Anne Imberty; Alessandro Dondoni; Cristina Nativi (2020). Fucosylated ubiquitin and orthogonally glycosylated mutant A28C: conceptually new ligands for Burkholderia ambifaria lectin (BambL). CHEMICAL SCIENCE, vol. 11, pp. 12662-12670, ISSN:2041-6520 DOI Accesso ONLINE all'editore

Denis M.; Softley C.; Giuntini S.; Gentili M.; Ravera E.; Parigi G.; Fragai M.; Popowicz G.; Sattler M.; Luchinat C.; Cerofolini L.; Nativi C. (2020). The Photocatalyzed Thiol-ene reaction: A New Tag to Yield Fast, Selective and reversible Paramagnetic Tagging of Proteins. CHEMPHYSCHEM, vol. 21, pp. 863-869-869, ISSN:1439-4235 DOI Accesso ONLINE all'editore

Amedei A.; Asadzadeh F.; Papi F.; Vannucchi M.G.; Ferrucci V.; Bermejo I.A.; Fragai M.; De Almeida C.V.; Cerofolini L.; Giuntini S.; Bombaci M.; Pesce E.; Niccolai E.; Natali F.; Guarini E.; Gabel F.; Traini C.; Catarinicchia S.; Ricci F.; Orzalesi L.; Berti F.; Corzana F.; Zollo M.; Grifantini R.; Nativi C. (2020). A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer. ISCIENCE, vol. 23, pp. 0-53, ISSN:2589-0042 DOI

Ciaco S.; Humbert N.; Real E.; Boudier C.; Francesconi O.; Roelens S.; Nativi C.; Seguin-Devaux C.; Mori M.; Mely Y. (2020). A Class of Potent Inhibitors of the HIV-1 Nucleocapsid Protein Based on Aminopyrrolic Scaffolds. ACS MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 698-705, ISSN:1948-5875 DOI

Francesconi O.; Ienco A.; Nativi C.; Roelens S. (2020). Effective Recognition of Caffeine by Diaminocarbazolic Receptors. CHEMPLUSCHEM, vol. 85, pp. 1369-1373, ISSN:2192-6506 DOI

Cristina Nativi (2020). Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis. JOURNAL OF ORGANIC CHEMISTRY, pp. 5038-5047, ISSN:0022-3263

Francesconi O.; Cicero F.; Nativi C.; Roelens S. (2020). A Preorganized Hydrogen-Bonding Motif for the Molecular Recognition of Carbohydrates. CHEMPHYSCHEM, vol. 21, pp. 257-262, ISSN:1439-4235 DOI

Cristina Nativi (2020). Modulation of immune responses using adjuvants to facilitate therapeutic vaccination. IMMUNOLOGICAL REVIEWS, vol. 296, pp. 169-190, ISSN:0105-2896

Cristina Nativi (2020). On the scope of SuFEx as a bioorthogonal click process. NEW JOURNAL OF CHEMISTRY, vol. 44, pp. 4678-4680, ISSN:1369-9261

Cristina Nativi, Francesco Papi, Stefano Roelens (2019). Tn antigen analogues: the synthetic way to "upgrade" an attracting tumour associated carbohydrate antigen (TACA). CHEMICAL COMMUNICATIONS, vol. 55, pp. 7729-7736, ISSN:1359-7345 DOI

Francesco Papi, Giulia Targetti, Linda Cerofolini, Claudio Luchinat, Marco Fragai, Cristina Nativi (2019). Nanoparticles for the multivalent presentation of a TnThr mimetic and as tool for solid state NMR coating investigation. PURE AND APPLIED CHEMISTRY, vol. 91, pp. 1471-1478, ISSN:0033-4545 DOI Accesso ONLINE all'editore

Francesca Maestrelli, Elisa Landucci, Enrico De Luca, Giulia Nerli, Maria Camilla Bergonzi, Vieri Piazzini, Domenico E.Pellegrini-Giampietro, Francesca Gullo, Andrea Becchetti, Francesco Tadini-Buoninsegni, Oscar Francesconi,Cristina Nativi (2019). Niosomal Formulation of a Lipoyl-Carnosine Derivative Targeting TRPA1 Channels in Brain. PHARMACEUTICS, vol. 11, pp. 669-680, ISSN:1999-4923 DOI Accesso ONLINE all'editore

Cristina Nativi (2019). A structurally constrained and immunogenic TnThr antigen mimetic. In: 12th International Symposium on Biorganic Chemistry, IUPAC, pp. 42-42.

Mura, P.; Mennini, N.; Nativi, C.; Richichi, B. (2018). In situ mucoadhesive-thermosensitive liposomal gel as a novel vehicle for nasal extended delivery of opiorphin.. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 122, pp. 54-61, ISSN:0939-6411 DOI

Oscar, Francesconi; Marco, Martinucci; Lorenzo Badii; Nativi, Cristina; Stefano, Roelens (2018). A Biomimetic Synthetic Receptor Selectively Recognising Fucose in Water. CHEMISTRY-A EUROPEAN JOURNAL, vol. 24, pp. 6828-6836, ISSN:0947-6539 DOI

Gracia, Raquel; Marradi, Marco*; Salerno, Gianluca; Pérez-Nicado, Rocmira; Pérez-San Vicente, Adrián; Dupin, Damien; Rodriguez, Javier; Loinaz, Iraida; Chiodo, Fabrizio; Nativi, Cristina (2018). Biocompatible single-chain polymer nanoparticles loaded with an antigen mimetic as potential anticancer vaccine. ACS MACRO LETTERS, vol. 7, pp. 196-200, ISSN:2161-1653 DOI Accesso ONLINE all'editore

Demartini, Chiara; Greco, Rosaria; Zanaboni, Anna Maria; Francesconi, Oscar; Nativi, Cristina; Tassorelli, Cristina; Deseure, Kristof (2018). Antagonism of Transient Receptor Potential Ankyrin Type-1 Channels as a Potential Target for the Treatment of Trigeminal Neuropathic Pain: Study in an Animal Model. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 19, pp. 3320-3340, ISSN:1422-0067 DOI

Goyard, David; Baldoneschi, Veronica; Varrot, Annabelle; Fiore, Michele; Imberty, Anne*; Richichi, Barbara; Renaudet, Olivier; Nativi, Cristina (2018). Multivalent Glycomimetics with Affinity and Selectivity toward Fucose-Binding Receptors from Emerging Pathogens. BIOCONJUGATE CHEMISTRY, vol. 29, pp. 83-88, ISSN:1043-1802 DOI Accesso ONLINE all'editore

Benito-Alifonso, David; Richichi, Barbara; Baldoneschi, Veronica; Berry, Monica; Fragai, Marco; Salerno, Gianluca; Galan, M. Carmen*; Nativi, Cristina (2018). Quantum Dot-Based Probes for Labeling and Imaging of Cells that Express Matrix Metalloproteinases. ACS OMEGA, vol. 3, pp. 9822-9826, ISSN:2470-1343 DOI Accesso ONLINE all'editore

Salerno, Gianluca; Scarano, Simona; Mamusa, Marianna; Consumi, Marco; Giuntini, Stefano; Macagnano, Antonella; Nativi, Stefano; Fragai, Marco; Minunni, Maria; Berti, Debora; Magnani, Agnese; Nativi, Cristina; Richichi, Barbara (2018). A small heterobifunctional ligand provides stable and water dispersible core-shell CdSe/ZnS quantum dots (QDs). NANOSCALE, vol. 10, pp. 19720-19732, ISSN:2040-3364 DOI Accesso ONLINE all'editore

Alberto Marra, Jiajia Dong, Tiancheng Ma, Stefano Giuntini, Elisa Crescenzo, Linda Cerofolini, Marco Martinucci, Claudio Luchinat, Marco Fragai, Cristina Nativi, Alessandro Dondoni (2018). Protein Glycosylation through Sulfur Fluoride Exchange (SuFEx) Chemistry: The Key Role of a Fluorosulfate Thiolactoside. CHEMISTRY-A EUROPEAN JOURNAL, vol. 24, pp. 1-8, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Arosio, Paolo; Comito, Giuseppina; Orsini, Francesco; Lascialfari, Alessandro; Chiarugi, Paola; Ménard-Moyon, Cécilia*; Nativi, Cristina; Richichi, Barbara (2018). Conjugation of a GM3 lactone mimetic on carbon nanotubes enhances the related inhibition of melanoma-associated metastatic events. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 16, pp. 6086-6095, ISSN:1477-0520 DOI Accesso ONLINE all'editore

Fragai, Marco; Comito, Giuseppina; Di Cesare Mannelli, Lorenzo; Gualdani, Roberta; Calderone, Vito; Louka, Alexandra; Richichi, Barbara; Francesconi, Oscar; Angeli, Andrea; Nocentini, Alessio; Gratteri, Paola; Chiarugi, Paola; Ghelardini, Carla; Tadini-Buoninsegni, Francesco; Supuran, Claudiu T; Nativi, Cristina (2017). Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX). JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, pp. 9003-9011, ISSN:1520-4804 DOI

Cerofolini, Linda; Baldoneschi, Veronica; Dragoni, Elisa; Storai, Andrea; Mamusa, Marianna; Berti, Debora; Fragai, Marco; Richichi, Barbara; Nativi, Cristina (2017). Synthesis and binding monitoring of a new nanomolar PAMAM-based matrix metalloproteinases inhibitor (MMPIs). BIOORGANIC & MEDICINAL CHEMISTRY, vol. 25, pp. 523-527, ISSN:0968-0896 DOI Accesso ONLINE all'editore

Demartini, Chiara; Tassorelli, Cristina; Zanaboni, Anna Maria; Tonsi, Germana; Francesconi, Oscar; Nativi, Cristina; Greco, Rosaria (2017). The role of the transient receptor potential ankyrin type-1 (TRPA1) channel in migraine pain: evaluation in an animal model. THE JOURNAL OF HEADACHE AND PAIN, vol. 18, pp. 94-94, ISSN:1129-2369 DOI Accesso ONLINE all'editore

Cristina Nativi, Oscar Francesconi, Agnese Magnani, Marco Fragai, Barbara Richichi, Marco Consumi, Stefania Lamponi, Gemma Leone, Veronica Baldoneschi (2017). Functionalized Hyaluronic Acid. Numero: WO2018/029588 Università di Firenze, Università di Siena, INSTM

Fallarini, Silvia; Brittoli, Alvaro; Fiore, Michele; Lombardi, Grazia; Renaudet, Olivier; Richichi, Barbara; Nativi, Cristina (2017). Immunological characterization of a rigid α-Tn mimetic on murine iNKT and human NK cells. GLYCOCONJUGATE JOURNAL, vol. 34, pp. 553-562, ISSN:0282-0080 DOI Accesso ONLINE all'editore

Gunay, Gokhan; Sardan Ekiz, Melis; Ferhati, Xhenti; Richichi, Barbara; Nativi, Cristina; Tekinay, Ayse B.; Guler, Mustafa O. (2017). Antigenic GM3 Lactone Mimetic Molecule Integrated Mannosylated Glycopeptide Nanofibers for the Activation and Maturation of Dendritic Cells. ACS APPLIED MATERIALS & INTERFACES, vol. 9, pp. 16035-16042, ISSN:1944-8244 DOI Accesso ONLINE all'editore

Airoldi, Cristina; D'Orazio, Giuseppe; Richichi, Barbara; Guzzi, Cinzia; Baldoneschi, Veronica; Colombo, Laura; Salmona, Mario; Nativi, Cristina; Nicotra, Francesco; La Ferla, Barbara (2016). Structural Modifications of cis-Glycofused Benzopyran Compounds and Their Influence on the Binding to Amyloid b-Peptide. CHEMISTRY - AN ASIAN JOURNAL, vol. 11, pp. 299-309, ISSN:1861-4728 DOI Accesso ONLINE all'editore

Richichi, Barbara; Pastori, Claudia; Gherardi, Stefano; Venuti, Assunta; Cerreto, Antonella; Sanvito, Francesca; Toma, Lucio; Lopalco, Lucia; Nativi, Cristina (2016). GM‑3 Lactone Mimetic Interacts with CD4 and HIV‑1 Env Proteins, Hampering HIV‑1 Infection without Inducing a Histopathological Alteration. ACS INFECTIOUS DISEASES, vol. 2, pp. 564-571, ISSN:2373-8227 DOI

Nativi, Cristina; Magnani, Agnese; Leone, Gemma; Lamponi, Stefania; Consumi, Marco; Fragai, Marco; Baldoneschi, Veronica; Richichi, Barbara; Francesconi, Oscar (2016). Acido Ialuronico funzionalizzato. Numero: 16432PTIT/as INSTM

Richichi, B.; Baldoneschi, V.; Burgalassi, S.; Fragai, M.; Vullo, D.; Akdemir, A.; Dragoni, E.; Louka, A.; Mamusa, M.; Monti, D.; Berti, D.; Novellino, E.; Rosa, G. De; Supuran, C.T.; Nativi, C. (2016). A Divalent PAMAM-Based Matrix Metalloproteinase/Carbonic Anhydrase Inhibitor for the Treatment of Dry Eye Syndrome. CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, pp. 1714-1721, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Gentili, Matteo; Nativi, Cristina; Francesconi, Oscar; Roelens, Stefano (2016). Synthetic receptors for molecular recognition of carbohydrates. In: Amelia Pilar Rauter, Thisbe K Lindhorst, Yves Queneau. Carbohydrate Chemistry Volume 41, pp. 149-186 Royal Society of Chemistry, ISBN:9781782621218. DOI Accesso ONLINE all'editore

Baldoneschi, Veronica; Cerofolini, Linda; Dragoni, Elisa; Storai, Andrea; Luchinat, Claudio; Fragai, Marco; Richichi, Barbara; Nativi, Cristina (2016). Active-Site Targeting Paramagnetic Probe for Matrix Metalloproteinases. CHEMPLUSCHEM, vol. 81, pp. 1333-1338, ISSN:2192-6506 DOI Accesso ONLINE all'editore

Richichi, Barbara; Comito, Giuseppina; Renaudet, Olivier; Fiore, Michele; Marra, A.; Stecca, B.; Pasquato, L.; Chiarugi, P.; Nativi, C. (2016). Role of a Preorganized Scaffold Presenting Four Residues of a GM‑3 Lactone Mimetic on Melanoma Progression. ACS MEDICINAL CHEMISTRY LETTERS, vol. 7, pp. 28-33, ISSN:1948-5875 DOI Accesso ONLINE all'editore

Share, Andrew I.; Patel, Khushali; Nativi, Cristina; Cho, Eun J.; Francesconi, Oscar; Busschaert, Nathalie; Gale, Philip A.; Roelens, Stefano; Sessler, Jonathan L. (2016). Chloride anion transporters inhibit growth of methicillin-resistant: Staphylococcus aureus (MRSA) in vitro. CHEMICAL COMMUNICATIONS, vol. 52, pp. 7560-7563, ISSN:1359-7345 DOI Accesso ONLINE all'editore

Gaelle Michaud; Ricardo Visini; Bergmann Myriam; Salerno Gianluca; Bosco Rosa; Gillon Emilie; Richichi Barbara; Nativi Cristina; Imberty Anne; Stocker Achim; Tamis Darbre; Jean-Louis Reymond. (2016). Overcoming antibiotic resistance in Pseudomonas aeruginosa biofilms using glycopeptide dendrimers. CHEMICAL SCIENCE, vol. 7, pp. 166-182, ISSN:2041-6520 DOI

Nativi, Cristina; Richichi, Barbara; Roelens, Stefano (2015). Carbohydrate-containing Matrix Metalloproteinase Inhibitors (MMPIs): a second Childhood for sulfonamidic inhibitors?. In: Martin-Santamaria S.,Jimenez-Barbero J.,Canada F.J.. RSC Drug Discovery Series, pp. 242-254 RCS Drug Discovery Series, ISBN:978-1-84973-939-9. Accesso ONLINE all'editore

Francesconi, O.; Nativi, C.; Gabrielli, G.; De Simone, I.; Noppen, S.; Balzarini, J.; Liekens, S.; Roelens, S. (2015). Antiviral activity of synthetic aminopyrrolic carbohydrate binding agents: targeting the glycans of viral gp120 to inhibit HIV entry. CHEMISTRY, vol. 21, pp. 10089-10093, ISSN:1521-3765

Ardà, A.; Bosco, R.; Sastre, J.; Canada, J.F.; André, S.; Gabius, H.J.; Richichi, B.; Jimenez-Barbero, J.; Nativi, C. (2015). Structural Insight into the Binding of Sugar Receptor (Lectin) to a Synthetic Tricyclic Tn Mimetic and its Glycopeptide Version. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, pp. 6823-6831, ISSN:1099-0690 DOI

Gualdani, Roberta; Ceruti, Stefania; Magni, Giulia; Merli, Davide; di Cesare Mannelli, Lorenzo; Francesconi, Oscar; Richichi, Barbara; la Marca, Giancarlo; Ghelardini, Carla; Moncelli, Maria Rosa; Nativi, Cristina (2015). The Role of TRPA1 and TRPV1 Channels in Orofacial Pain. BIOPHYSICAL JOURNAL, vol. 108, pp. 123a-123a, ISSN:0006-3495 DOI

Gualdani, R.; Cerruti, S.; Magni, G.; Merli, D.; Di Cesare Mannelli, L.; Francesconi, O.; Richichi, B.; la Marca, G.; Ghelardini, C.; Moncelli, M.R.; Nativi, C. (2015). Lipoic-Based TRPA1/TRPV1 Antagonist to Treat Orofacial Pain. ACS CHEMICAL NEUROSCIENCE, vol. 6, pp. 380-385, ISSN:1948-7193 DOI

Mennini, Natascia; Mura, Paola; Nativi, Cristina; Richichi, Barbara; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla (2015). Injectable liposomal formulations of opiorphin as a new therapeutic strategy in pain management. FUTURE SCIENCE OA, vol. 1, pp. 1-10, ISSN:2056-5623 Accesso ONLINE all'editore

Park, S.-H.; Choi, Y.P.; Park, J.; Share, A.; Francesconi, O.; Nativi, C.; Namkung, W.; Sessler, J. L.; Roelens, S.; Shin, I. (2015). Synthetic aminopyrrolic receptors have apoptosis inducing activity. CHEMICAL SCIENCE, vol. 6, pp. 7284-7292, ISSN:2041-6520

Nativi, Cristina; Ghelardini, Carla; LA MARCA, Giancarlo (2014). NOVEL COMPOUNDS HAVING ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITY. Numero: PCT WO/2015/128697 CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI [IT/IT]; Piazza S.Marco, 4 I-50121 Firenze (IT). UNIVERSITA' DEGLI STUDI DI FIRENZE [IT/IT]; Piazza San Marco, 4 I-50121 Firenze (IT)

Renato Ribeiro-Viana;Elena Bonechi;Javier Rojo;Clara Ballerini;Giuseppina Comito;Barbara Richichi;Cristina Nativi (2014). Human dendritic cell activation induced by a permannosylated dendron containing an antigenic GM3-lactone mimetic. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, vol. 10, pp. 1317-1324, ISSN:1860-5397 DOI

C. Nativi; B. Richichi; L. Toma; C. Lunghi (2014). Synthetic Immunogenic Glycoconjugate for melanoma immunotherapy. Numero: US 08680043 AUOC

Oscar Francesconi;Matteo Gentili;Cristina Nativi;Ana Ardá;F. Javier Cañada;Jesús Jiménez-Barbero;Stefano Roelens (2014). Systematic Dissection of an Aminopyrrolic Cage Receptor for β-Glucopyranosides Reveals the Essentials for Effective Recognition. CHEMISTRY-A EUROPEAN JOURNAL, vol. 20, pp. 6081-6091, ISSN:0947-6539 DOI

Richichi, Barbara; Thomas, Baptiste; Fiore, Michele; Bosco, Rosa; Qureshi, Huma; Nativi, Cristina; Renaudet, Olivier; Benmohamed, Lbachir (2014). A Cancer Therapeutic Vaccine based on Clustered Tn-Antigen Mimetics Induces Strong Antibody-Mediated Protective Immunity. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 53, pp. 11917-11920, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Barbara Richichi; Jennifer McKimm-Breschkin; Veronica Baldoneschi; Cristina Nativi (2014). Stereoselective synthesis and sialidase inhibition properties of KDO-based glycosyloxathiins. ARKIVOC, pp. 65-79, ISSN:1551-7012

Massimo Manuelli; Silvia Fallarini; Grazia Lombardi; Claudio Sangregorio; Cristina Nativi; Barbara Richichi (2014). Iron oxide superparamagnetic nanoparticles conjugated with a conformationally blocked -Tn antigen mimetic for macrophage activation. NANOSCALE, vol. 6, pp. 7643-7655, ISSN:2040-3364 DOI

Francesconi, Oscar; Nativi, Cristina; Gabrielli, Gabriele; Gentili, Matteo; Palchetti, Marco; Bonora, Beatrice; Roelens, Stefano (2013). Pyrrolic tripodal receptors for the molecular recognition of carbohydrates: Ditopic receptors for dimannosides. CHEMISTRY-A EUROPEAN JOURNAL, vol. 19, pp. 11742-11752, ISSN:0947-6539 DOI

Tania Fiaschi;Elisa Giannoni;Maria Letizia Taddei;Paolo Cirri;Alberto Marini;Gianfranco Pintus;Cristina Nativi;Barbara Richichi;Andrea Scozzafava;Fabrizio Carta;Eugenio Torre;Claudiu T. Supuran;Paola Chiarugi (2013). Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells. CELL CYCLE, vol. 12, pp. 1791-1801, ISSN:1538-4101 DOI

Marco Bartoloni;Blanca E. Domínguez;Elisa Dragoni;Barbara Richichi;Marco Fragai;Sabine André;Hans-Joachim Gabius;Ana Ardá;Claudio Luchinat;Jesús Jiménez-Barbero;Cristina Nativi (2013). Targeting Matrix Metalloproteinases: Design of a Bifunctional Inhibitor for Presentation by Tumour-Associated Galectins. CHEMISTRY-A EUROPEAN JOURNAL, vol. 19, pp. 1896-1902, ISSN:0947-6539 DOI

Barbara Richichi;Giuseppina Comito;Linda Cerofolini;Gabriele Gabrielli;Alberto Marra;Lisa Moni;Alice Pace;Lucia Pasquato;Paola Chiarugi;Alessandro Dondoni;Lucio Toma;Cristina Nativi (2013). Multivalent presentation of ahydrolytically stable GM 3 lactone mimetic as modulator of melanoma cells motility and adhesion. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, pp. 2756-2763, ISSN:0968-0896 DOI

Nativi, Cristina; Gualdani, R; Dragoni, Elisa; DI CESARE MANNELLI, Lorenzo; Sostegni, S; Norcini, M; Gabrielli, G; LA MARCA, Giancarlo; Richichi, Barbara; Francesconi, Oscar; Moncelli, MARIA ROSA; Ghelardini, Carla; Roelens, Stefano (2013). A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain. SCIENTIFIC REPORTS, vol. 3, pp. 1-10, ISSN:2045-2322 DOI

Barbara Richichi;Carlotta Lunghi;Athanasios Papakyriakou;Oscar Francesconi;Cristina Nativi (2013). Sialylexoenitols as precursors for new analogues of sialidase inhibitors. PURE AND APPLIED CHEMISTRY, vol. 85, pp. 1803-1811, ISSN:0033-4545 DOI

L. Gargiulo;M. Papaioannou;M. Sica;G. Talini;A. Chaidos;B. Richichi;A. V. Nikolaev;C. Nativi;M. Layton;J. de la Fuente;I. Roberts;L. Luzzatto;R. Notaro;A. Karadimitris (2013). Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria. BLOOD, vol. 121, pp. 2753-2761, ISSN:0006-4971 DOI

P. Arapitsas; B. Turchetti; F. Melani; D.Tacconi; C. Nativi; A. Romani; S. Menichetti; P. Buzzini (2013). In Vitro Synergistic Anti-yeast Activity between Galloyl Derivatives and Amphotericin B. THE NATURAL PRODUCTS JOURNAL, vol. 3, pp. 131-139, ISSN:2210-3155 DOI

Anna Bernardi;Jesus Jiménez-Barbero;Alessandro Casnati;Cristina De Castro;Tamis Darbre;Franck Fieschi;Jukka Finne;Horst Funken;Karl-Erich Jaeger;Martina Lahmann;Thisbe K. Lindhorst;Marco Marradi;Paul Messner;Antonio Molinaro;Paul V. Murphy;Cristina Nativi;Stefan Oscarson;Soledad Penadés;Francesco Peri;Roland J. Pieters;Olivier Renaudet;Jean-Louis Reymond;Barbara Richichi;Javier Rojo;Francesco Sansone;Christina Schäffer;W. Bruce Turnbull;Trinidad Velasco-Torrijos;Sébastien Vidal;Stéphane Vincent;Tom Wennekes;Han Zuilhof;Anne Imberty (2013). Multivalent glycoconjugates as anti-pathogenic agents. CHEMICAL SOCIETY REVIEWS, vol. 42, pp. 4709-4727, ISSN:0306-0012 DOI

Barbara Richichi;Anne Imberty;Emilie Gillon;Rosa Bosco;Ieva Sutkeviciute;Franck Fieschi;Cristina Nativi (2013). Synthesis of a selective inhibitor of a fucose binding bacterial lectin from Burkholderia ambifaria. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 11, pp. 4086-4094, ISSN:1477-0520 DOI

Mattia Mori;Emanuele De Lorenzo;Eugenio Torre;Marco Fragai;Cristina Nativi;Claudio Luchinat;Annarosa Arcangeli (2012). A Highly Soluble Matrix Metalloproteinase-9 Inhibitor for Potential Treatment of Dry Eye Syndrome. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, vol. 111, pp. 289-295, ISSN:1742-7835 DOI

C. Nativi; O. Francesconi; G. Gabrielli; I. De Simone; B. Turchetti; T. Mello; L. Di Cesare Mannelli; C. Ghelardini; P. Buzzini; S. Roelens (2012). Aminopyrrolic synthetic receptors for monosaccharides: A class of carbohydrate-binding agents endowed with antibiotic activity versus pathogenic yeasts. CHEMISTRY, vol. 18, pp. 5064-5072, ISSN:1521-3765 DOI Accesso ONLINE all'editore

R. U. Kadam; M. Bergmann; M. Hurley; D. Garg; M. Cacciarini; M. A. Swiderska; C. Nativi; M. Sattler; A. R. Smith; P. Williams; M. Càmara; A. Stocker; T. Darbre; J. L. Reymond (2011). A glycopeptide dendrite inhibitor of the galactose-specific lectin LecA and of Pseudomonas Aeruginosa biofilm. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 50, pp. 10613-10635, ISSN:1433-7851 DOI

C. Nativi; L. Toma; B. Richichi; C. Lunghi (2011). Synthetic Immunogenic Glycoconjugate for Melanoma Immunotherapy. Numero: WO/2011/055324 A1 AOUC

A. Ardá; F. J. Cañada; C. Nativi; O. Francesconi; G. Gabrielli; A. Ienco; J. Jiménez-Barbero; S. Roelens (2011). Chiral diaminopyrrolic receptors for selective recognition of mannosides, part 2: A 3D view of the recognition modes by X-ray, NMR spectroscopy and molecular modeling. CHEMISTRY, vol. 17, pp. 4821-4829, ISSN:1521-3765 DOI Accesso ONLINE all'editore

C. Nativi; E. Dragoni; B. Richichi; S. Roelens (2011). Diels-Alder Based Synthesis of Glycomimetics. In: O. Renaudet and N. Spinelli. Synthesis and Biological application of Glycoconjugates, pp. 240-254, Grenoble: O. Renaudet and N. Spinelli, ISBN:978-1-60805-277-6. DOI

B. Richichi; L. Luzzatto; R. Notaro; G. la Marca; C. Nativi (2011). Synthesis of the essential core of the human glycosylphosphatidylinositol (GPI) anchor. BIOORGANIC CHEMISTRY, vol. 39, pp. 88-93, ISSN:0045-2068 DOI

C. Nativi; O. Francesconi; G. Gabrielli; A. Vacca; S. Roelens (2011). Chiral diaminopyrrolic receptors for selective recognition of mannosides, part 1: Design, synthesis, and affinities of second-generation tripodal receptors. CHEMISTRY, vol. 17, pp. 4814-4820, ISSN:1521-3765 DOI Accesso ONLINE all'editore

M. Cacciarini; C. Nativi; M. Norcini; S. Staderini; O. Francesconi; S. Roelens (2011). Pyrrolic tripodal receptors for carbohydrates. Role of functional groups and binding geometry on carbohydrate recognition. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, pp. 1085-1091, ISSN:1477-0520 DOI

A. Ardà; C. Venturi; C. Nativi; O. Francesconi; F. Javier Cañada; J. Jiménez-Barbero; S. Roelens (2010). Selective Recognition of -Mannosides by Synthetic Tripodal Receptors: A 3D view of the Recognition Mode by NMR. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. -, pp. 64-71, ISSN:1434-193X

C. Nativi; C. Ghelardini; E. Dragoni (2010). Composti ad efficacia sia analgesica che antiperalgesica. Numero: 10049PTIT C. Nativi, C. Ghelardini, E. Dragoni

NATIVI C.; GHELARDINI C.; LA MARCA G.; DRAGONI E. (2010). COMPOUNDS WITH BOTH ANALGESIC AND ANTI-HYPERALGESIC EFFICACY. Numero: WO 2011080725 A1 NATIVI, Cristina [IT/IT]; (IT).GHELARDINI, Carla [IT/IT]; (IT).LA MARCA, Giancarlo [IT/IT]; (IT).DRAGONI, Elisa [IT/IT]; (IT).CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI (INSTM) [IT/IT]; Piazza San Marco, 4 I-50121 Firenze (IT) (For All Designated States Except US)

Arcangeli A.; Toma L.; Contiero L.; Crociani O.; Legnani L.; Lunghi C.; Nesti E.; Moneti G.; Richichi B.; Nativi C. (2010). Stable GM3 lactone mimetic raises antibodies specific for the antigens expressed on melanoma cells. BIOCONJUGATE CHEMISTRY, vol. 21, pp. 1432-1438, ISSN:1043-1802 DOI

Ardá, A; Venturi, C; Nativi, C; Francesconi, O; Cañada, F.J; Jiménez-Barbero, J; Roelens, S (2010). Selective Recognition of β-Mannosides by Synthetic Tripodal Receptors: A 3D View of the Recognition Mode by NMR. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, pp. 64-71, ISSN:1434-193X, Wiley-V C H Verlag Gmbh: DOI

Ardà, A.; Venturi, C.; Nativi, C.; Francesconi, O.; Gabrielli, G.; Canada F. X.; Jimenez-Barbero, J.; Roelens, S.; (2010). A Chiral Pyrrolic Tripodal Receptor Enantioselectively Recognizes beta-Mannose and beta-Mannosides. CHEMISTRY-A EUROPEAN JOURNAL, vol. 16, pp. 414-418, ISSN:0947-6539

E.Attolino; V.Calderone; E.Dragoni; M.Fragai; B.Richichi; C.Luchinat; C.Nativi (2010). Structure-Based Approach to Nanomolar, Water Soluble Matrix Metalloproteinases Inhibitors (MMPIs). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, pp. 5919-5925, ISSN:0223-5234 DOI

G. Gabrielli; F. Melani; S. Bernasconi; C. Lunghi; B. Richichi; P. Rollin; C. Venturi; C. Nativi (2009). Stereoselective synthesis of 1,3-disaccharides through Diels-Alder reactions: Part 2: convenient protecting groups for heterodienes and conformational evaluations. JOURNAL OF CARBOHYDRATE CHEMISTRY, vol. 28, pp. 124-141, ISSN:0732-8303 DOI Accesso ONLINE all'editore

S. Ristori; E. Di Cola; C. Lunghi; B. Richichi; C. Nativi (2009). Structural study of liposomes loaded with a GM3 lactone analogue for the targeting of tumor epitopes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, vol. 1788, pp. 2518-2525, ISSN:0005-2736 DOI

C. Nativi; L. Toma; B. Richichi; C. Lunghi (2009). Glicoconiugato sintetico immunogeno utile per l'immunoterapia del melanoma. Numero: FI2009A000230 Azienda Ospedaliera Universitaria di Careggi

E. Dragoni; V. Calderone; M. Fragai; R. Jaiswal; C. Luchinat; C. Nativi (2009). Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties. BIOCONJUGATE CHEMISTRY, vol. 20, pp. 719-727, ISSN:1043-1802 DOI Accesso ONLINE all'editore

M. Altamura; E. Dragoni; A. S. Infantino; L. Legnani; S. B. Ludbrook; G. Menchi; L. Toma; C. Nativi (2009). Cyclic Glycopeptidomimetics Through a Versatile Sugar-based Scaffold. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, pp. 3841-3844, ISSN:0960-894X Accesso ONLINE all'editore

J. Jimenez-Barbero; E. Dragoni; C. Venturi; F. Nannucci; A. Arda; M. Fontanella; S. Andre; F. J. Canada; H.-J. Gabius; C. Nativi (2009). Alpha-O-linked Glycopeptide Mimetics: Synthesis, Conformation Analysis and Interactions with Viscumin, a Galactoside-Binding Model Lectin. CHEMISTRY-A EUROPEAN JOURNAL, vol. 15, pp. 10423-10431, ISSN:0947-6539

E.M.V. Johansson; S.A. Crusz; E. Kolomiets; L. Buts; R.U. Kadam; M. Cacciarini; K.-M. Bartels; S.P. Diggle; M. Cámara; P. Williams; R. Loris; C. Nativi; F. Rosenau; K.-E. Jaeger; T. Darbre; J.-L. Reymond (2008). Inhibition and Dispersion of Pseudomonas aeruginosa Biofilms by Glycopeptide Dendrimers Targeting the Fucose-Specific Lectin LecB. CHEMISTRY & BIOLOGY, vol. 15, pp. 1249-1257, ISSN:1074-5521 DOI

C. Nativi; S. Roelens (2008). 1-n Diols. Stuttgart: Thieme Verlag

G.Cipriani; A.Salvini; D.Buralli; C.Nativi; P.Baglioni (2007). Sintesi e caratterizzazione di oligomeri e polimeri poliossidrilati per il trattamento di legni archeologici. In: II Convegno La diagnostica e la conservazione di manufatti lignei: il legno bagnato, Cantiere delle Navi Antiche di Pisa, II Convegno La diagnostica e la conservazione di manufatti lignei: il legno bagnato, Cantiere delle Navi Antiche di Pisa, 5-7/12/07, PRIN 2005 - cantiere delle Navi Antiche di Pisa, pp. 55-55.

G.Cipriani; A.Salvini; D.Buralli; C.Nativi; P.Baglioni (2007). Composti oligo- e polisaccaridi per il consolidamento del legno archeologico. In: XXVI Convegno Interregionale- Toscana Umbria Marche Abruzzo, Assisi, Assisi, 26-28/09/2007, TUMA - SCI, pp. 21-21.

I. Bertini; V. Calderone; M. Fragai; A. Giachetti; M. Loconte; C. Luchinat; M. Maletta; C. Nativi; K. J. Yeo (2007). Exploring the subtleties of drug-receptor interactions: The case of matrix metalloproteinases. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, pp. 2466-2475, ISSN:0002-7863 DOI Accesso ONLINE all'editore

C. NATIVI; M. CACCIARINI; O. FRANCESCONI; G. MONETI; S. ROELENS (2007). A b-Mannoside-Selective Pyrrolic Tripodal Receptor. ORGANIC LETTERS, vol. 9, pp. 4685-4688, ISSN:1523-7060 DOI Accesso ONLINE all'editore

M. CACCIARINI; S. MENICHETTI; C. NATIVI; B. RICHICHI (2007). The hetero Diels-Alder approach to carbohydrate-containing molecular scaffolding. CURRENT ORGANIC SYNTHESIS, vol. 4, pp. 47-57, ISSN:1570-1794 DOI

L. Toma; E. Di Cola; A. Ienco; L. Legnani; C. Lunghi; G. Moneti; B. Richichi; S. Ristori; D. Dell'Atti; C. Nativi (2007). Synthesis, conformational studies, binding assessment and liposome insertion of a thioether-bridged mimetic of the antigen GM3 ganglioside lactone. CHEMBIOCHEM, vol. 8, pp. 1646-1649, ISSN:1439-4227 DOI

L. Legnani; C. Lunghi; F. Albini Marione; C. Nativi; B. Richichi; L. Toma (2007). Alternative Mechanistic Paths in the Hetero Diels-Alder Reaction of Oxothiones: A Theoretical Study. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, pp. 3547-3554, ISSN:1434-193X DOI

M. CACCIARINI; E. CORDIANO; C. NATIVI; S. ROELENS (2007). A tricatecholic receptor for carbohydrate recognition: synthesis and binding studies. JOURNAL OF ORGANIC CHEMISTRY, vol. 72, pp. 3933-3936, ISSN:0022-3263 DOI

C. NATIVI; M. CACCIARINI; O. FRANCESCONI; A. VACCA; G. MONETI; A. IENCO; S. ROELENS (2007). Pyrrolic Tripodal Receptors Effectively Recognizing Monosaccharides. Affinity Assessment through a Generalized Binding Descriptor.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, pp. 4377-4385, ISSN:0002-7863 DOI

M. Altamura; G. Balacco; F. Cuda; A. Guidi; S. Meini; S. Menichetti; C. Nativi; F. Pasqui (2006). A Way to Manage the Thermal Flexibility of Ligand Candidates for Bioassays. TETRAHEDRON, vol. 62, pp. 6754-6761, ISSN:0040-4020, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010: DOI

E. ATTOLINO; C. NATIVI (2006). Process for the preparation of S-carbamoyl cysteine derivatives. Numero: WO 2006056233 E. ATTOLINO; C. NATIVI

V. Calderone; M. Fragai; C. Luchinat; C. Nativi; B. Richichi; S. Roelens (2006). A high-affinity carbohydrate-containing inhibitor of matrix metalloproteinases. CHEMMEDCHEM, vol. 1, pp. 598-601, ISSN:1860-7179 DOI

O. FRANCESCONI; A. IENCO; G. MONETI; C. NATIVI; S. ROELENS (2006). A Self-Assembled Pyrrolic Cage Receptor Specifically Recognizes β-Glucopyranosides. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 45, pp. 6693-6696, ISSN:1433-7851 DOI

G.Cipriani; A.Salvini; D.Buralli; C.Nativi; P.Baglioni (2006). Synthesis and characterization of oligo- and polysaccharides for their use in wood conservation. In: 3rd European Students Conference on Physical, Organic and Polymer Chemistry”, Vienna, Austria, 18-20/09/2006, Herwijnen - Wagner Editors, pp. L02-L02.

A. ROMANI; S. MENICHETTI; P. ARAPITSAS; C. NATIVI; B. TURCHETTI; P. BUZZINI (2005). O-methylglucogalloyl esters: Synthesis and evaluation of their antimycotic avtivity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, pp. 4000-4003, ISSN:0960-894X DOI

M. Fragai; C. Nativi; B. Richichi; C. Venturi (2005). Design in silico, synthesis and binding evaluation of a carbohydrate-based scaffold for structurally novel inhibitors of matrix metalloproteinases. CHEMBIOCHEM, vol. 6, pp. 1345-1349, ISSN:1439-4227 DOI

S. Menichetti; M. Mori; C. Nativi (2005). Inverse Electron Demand Hetero Diels-Alder Reactions of Solid Supported alpha-Acilthiones. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 180, pp. 1327-1331, ISSN:1042-6507

BERTINI I; M. FRAGAI; LO CONTE M; LUCHINAT C; NATIVI C; VENTURI C (2005). Preparation of arylsulfonamide-substituted hydroxamic acid derivatives as matrix metalloproteinases inhibitors. Numero: WO/2006/013193 ABIOGEN PHARMA S.P.A. [IT/IT]; Via Meucci 36, I-56014 Loc. Ospedaletto (IT) (All Except US).BERTINI, Ivano [IT/IT]; (IT) (US Only).FRAGAI, Marco [IT/IT]; (IT) (US Only).LO CONTE, Mauro [IT/IT]; (IT) (US Only).LUCHINAT, Claudio [IT/IT]; (IT) (US Only).NATIVI, Cristina [IT/IT]; (IT) (US Only).VENTURI, Chiara [IT/IT]; (IT) (US Only).

S. Menichetti; M. Mori; C. Nativi (2005). Hetero Diels-Alder Reactions (HDAR) of α,α'-Dioxothiones on Solid Support. TETRAHEDRON, vol. 61, pp. 5005-5010, ISSN:0040-4020, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

M. ALTAMURA; G. COPPINI; F. CUDA; P. DAPPORTO; A. GUERRI; A. GUIDI; C. NATIVI; P. PAOLI; P. ROSSI (2005). A STRUCTURAL INVESTIGATION ON THE FLEXIBILITY OF CERTAIN O-PHTHALIC ACID DERIVATIVES. JOURNAL OF MOLECULAR STRUCTURE, vol. 749, pp. 20-30, ISSN:0022-2860 DOI

F. VENTURI; C. VENTURI; F. LIGUORI; M. CACCIARINI; M. MONTALBANO; C. NATIVI (2004). A new scaffold for the stereoselective synthesis of a-O-linked glycopeptide mimetics. JOURNAL OF ORGANIC CHEMISTRY, vol. 69, pp. 6153-6155, ISSN:0022-3263 DOI

Menichetti S.; Romani A.; Pinelli P. ; Vignolini P. ; Vincieri F.F.; Buzzini P.; Arapitsas P.; Nativi C. (2004). Synthesis of pirogalloyl esters methylglucosides and evaluation of antioxidant and antimycotic activity. In: XXII International confernce on polyphenols, pp. 655-656, ISBN:9521019778

A. VACCA; C. NATIVI; M. CACCIARINI; R. PERGOLI; S. ROELENS (2004). A New Tripodal Receptor for Molecular Recognition of Monosaccharides. A Paradigm for Assessing Glycoside Binding Affinities and Selectivities by 1H NMR Spectroscopy.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 126, pp. 16456-16465, ISSN:0002-7863 DOI

S. Menichetti; C. Nativi; P. Sarri; C. Viglianisi (2004). Sulfur Mediated Synthesis and Antimicrobial Activity of 4-Thioisosteres of Flavanoids. JOURNAL OF SULFUR CHEMISTRY, vol. 25, pp. 317-327, ISSN:1741-5993 DOI

G. Delogu; D. Fabbri; S. Menichetti; C. Nativi (2003). Torsional angles in 6,6'-bridged atropoisomeric biphenyls control the electrophilic substitution with phthalimidesulfenyl chloride. TETRAHEDRON, vol. 59, pp. 2131-2136, ISSN:0040-4020, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

A. BARTOLOZZI; S. PACCIANI; C. BENVENUTI; M. CACCIARINI; F. LIGUORI; S. MENICHETTI; C. NATIVI (2003). Totally Stereoselective Synthesis of 1,3-Disaccharides through Diels-Alder Reactions. JOURNAL OF ORGANIC CHEMISTRY, vol. 68, pp. 8529-8533, ISSN:0022-3263 DOI

S. MENICHETTI; C. NATIVI; G. CAPOZZI; G. CATELANI; F. D'ANDREA (2003). CONFORMATIONAL EVALUATION OF SOME 4-DEOXY-HEX-4-ENOPYRANOSE DERIVATIVES AND THEIR USE IN THE PREPARATION OF A PREVIOUSLY UNDESCRIBED CLASS OF 3-THIO-L-SORBOPYRANOSIDES AND THEIR 6-C-METHOXY ANALOGUES. CARBOHYDRATE RESEARCH, vol. 338, pp. 123-132, ISSN:0008-6215

G. Capozzi; G. Delogu; D. Fabbri; M. Marini; S. Menichetti; C. Nativi (2002). Regiocontrolled Synthesis of Enantiopure 3,3’-Thiosubstituted Biphenyls. JOURNAL OF ORGANIC CHEMISTRY, vol. 67, pp. 2019-2026, ISSN:0022-3263

G. Capozzi; S. Giannini; S. Menichetti; C. Nativi; A. Giolitti; R. Patacchini; E. Perrotta; M. Altamura; C. A. Maggi (2002). Design, Synthesis and Biological Activity of Carbohydrate-Containing Peptidomimetics as New Ligands for the Human Tachykinin NK-2 Receptor. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, pp. 2263-2266, ISSN:0960-894X, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

G. Capozzi; C. Ciampi; G. Delogu; S. Menichetti; C. Nativi (2001). Induction of a Preferred Sense of Twist in Flexible Diphenyls by Carbohydrate Scaffolds. Synthesis of Two “Naked” Ellagitannin Analogous. JOURNAL OF ORGANIC CHEMISTRY, vol. 66, pp. 8787-8792, ISSN:0022-3263, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671:

G. Capozzi; S. Giacomelli; S. Menichetti; C. Nativi (2001). Generation and Trapping of alpha,beta-Unsaturated Thioketones. Synthesis of 5,6-Dihydrothiopyranes. SYNTHESIS, vol. -, pp. 409-412, ISSN:0039-7881, Georg Thieme Verlag Stuttgart:Postfach 301120, D-70451 Stuttgart Germany:011 49 711 8931321, EMAIL: aboservice@thieme.de, INTERNET: http://www.thieme.de, Fax: 011 49 711 8931422:

A. Bartolozzi; G. Capozzi; S. Menichetti; C. Nativi (2001). Stereoselective 2-Deoxy-b-O-Glycoside Synthesis Based on the Remote Activation of Novel Oxathiine Donors. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. -, pp. 2083-2090, ISSN:1434-193X, Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328:

Capozzi, Giuseppe; LO NOSTRO, Pierandrea; Menichetti, Stefano; Nativi, Cristina; Sarri, P. (2001). Easy synthesis of polyphenolic 4-thiaflavans with a 'double-faced' antioxidant activity. CHEMICAL COMMUNICATIONS, vol. -, pp. 551-552, ISSN:1359-7345 DOI Accesso ONLINE all'editore

G. Capozzi; G. Delogu; A. Dettori; D. Fabbri; S. Menichetti; C. Nativi (2001). Desymmetrization of 2,2’,6,6’-tetramethoxybiphenyl by Regioselective Sulfenylation Reaction. TETRAHEDRON-ASYMMETRY, vol. 12, pp. 3313-3317, ISSN:0957-4166, PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OX5 1GB:

Capozzi, G; Menichetti, S; Nativi, C; Sarri, P; Viglianisi, C (2001). Sintesi di 4-Tiaflavani Poli-Idrossilati con una “Doppia” Attività Antiossidante. In: XXVII Convegno Nazionale Della Divisione Di Chimica Organica, Trieste, Italy, 3-7 settembre 2001, comitato organizzatore, pp. 0-0.

G. Capozzi; S. Menichetti; C. Nativi; A. Provenzani (2000). alpha-Oxosulfines, IV: Intramolecular Hetero Diels-Alder Reaction of alpha,alpha’-Dioxosulfines A New Access to the [3.3.1]-Bicyclic Skeleton. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. -, pp. 3721-3725, ISSN:1434-193X, Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328:

A. Bartolozzi; G. Capozzi; S. Menichetti; C. Nativi (2000). A New Procedure for the Preparation of beta-Keto-delta-lactones from Sugars and Their Transformation into Glycosyl Acceptors in Disaccharides Synthesis. ORGANIC LETTERS, vol. 2, pp. 251-253, ISSN:1523-7060

G. Capozzi; S. Menichetti; C. Nativi (2000). alpha-Oxothiones. IV: Electrophilic Substitution of Phenols with alpha,alpha’-Dioxothiones and ortho-Thioquinones”. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. -, pp. 3653-3657, ISSN:1434-193X, Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328:

B. Becattini; G. Capozzi; C. Falciani; S. Menichetti; C. Nativi; A. Salvini (2000). Carbohydrate-based peptido mimetics. Synthesis of two new scaffolds for combinatorial libraries. JOURNAL OF CARBOHYDRATE CHEMISTRY, vol. 19, pp. 653-657, ISSN:0732-8303

G. Capozzi; C. Nativi; A. Bartolozzi; C. Falciani; S. Menichetti; A. Paolacci (1999). Regio- and Stereoselective Synthesis of 4’-Thiaspiroacetals from Carbohydrates. JOURNAL OF ORGANIC CHEMISTRY, vol. 64, pp. 6490-6494, ISSN:0022-3263

B. Cantini; G. Capozzi; S. Menichetti; C. Nativi (1999). Phthalimidesulfenyl Chloride 12. Generation and Trapping of para-Monothioquinones. SYNTHESIS, vol. -, pp. 1046-1050, ISSN:0039-7881, Georg Thieme Verlag Stuttgart:Postfach 301120, D-70451 Stuttgart Germany:011 49 711 8931321, EMAIL: aboservice@thieme.de, INTERNET: http://www.thieme.de, Fax: 011 49 711 8931422:

G. Capozzi; C. Falciani; S. Menichetti; C. Nativi; B. Raffaelli (1999). Ortho-Thioquinones, New Acceptors for the Stereoselective Synthesis of Aryl 2-Deoxy-O-Glycosides.. CHEMISTRY-A EUROPEAN JOURNAL, vol. 5, pp. 1748-1754, ISSN:0947-6539

G. Capozzi; M. Fragai; S. Menichetti; C. Nativi (1999). alpha ',alpha '-dioxothiones, III Regio- and stereoselective ene and tandem "ene-cycloaddition'' reactions of 2,4-dioxopentane-3-thione. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 1999, pp. 3375-3379, ISSN:1434-193X

G. Capozzi; G. Delogu; M. A. Dettori; D. Fabbri; S. Menichetti; C. Nativi; R. Nuti (1999). Phthalimidesulfenyl Chloride 13. Regioselective Thiofunctionalization of Atropisomeric 2,2’-Biphenols. TETRAHEDRON LETTERS, vol. 40, pp. 4421-4424, ISSN:0040-4039, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

G. Capozzi; C. Nativi; A. Bartolozzi; C. Falciani; S. Menichetti (1999). Thiaspiroacetals from Carbohydrates. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 153-154, pp. 309-310, ISSN:1042-6507

B. Li; R. W. Franck; G. Capozzi; S. Menichetti; C. Nativi (1999). Glycosyl Tranfer to Nitrogen via Cycloaddition. ORGANIC LETTERS, vol. 1, pp. 111-114, ISSN:1523-7060, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671:

G. Capozzi; S. Menichetti; C. Nativi; C. Vergamini (1998). Formation and Hetero Diels-Alder Reaction of a-Iminosulfines: Synthesis of 5,6-Dihydro-1,4-Thiazin S-Oxides. SYNTHESIS, vol. -, pp. 915-918, ISSN:0039-7881, Georg Thieme Verlag Stuttgart:Postfach 301120, D-70451 Stuttgart Germany:011 49 711 8931321, EMAIL: aboservice@thieme.de, INTERNET: http://www.thieme.de, Fax: 011 49 711 8931422:

G. Capozzi; A. Corti; S. Menichetti; C. Nativi (1997). alpha-Oxosulfines Part 3. Generation and Trapping of alpha-Oxothioaldehyde S-Oxides". TETRAHEDRON LETTERS, vol. 38, pp. 5041-5044, ISSN:0040-4039, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

G. Capozzi; F. Mannocci; S. Menichetti; C. Nativi; S. Paoletti (1997). A versatile intermediate for complete alpha/beta stereocontrol in O-glycosidation reactions. CHEMICAL COMMUNICATIONS, vol. -, pp. 2291-2292, ISSN:1359-7345

G. Capozzi; C. Falciani; S. Menichetti; C. Nativi (1997). Phthalimidesulfenyl Chloride 11. Generation, General Reactivity and Synthetic Applications of Ortho-Thioquinones”. JOURNAL OF ORGANIC CHEMISTRY, vol. 62, pp. 2611-2615, ISSN:0022-3263

G. Boccardo; G. Capozzi; M. Giuntini; S. Menichetti; C. Nativi (1997). alpha,alpha’-Dioxothiones Part 2. Asymmetric Diels-Alder Reactions of Chiral Non-Racemic alpha,alpha’-Dioxothiones”. TETRAHEDRON, vol. 53, pp. 17383-17394, ISSN:0040-4020, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:

G. Capozzi; R. Franck; S. Menichetti; C. Nativi; S. Paoletti (1997). Sulfur-Mediated Carbohydrate Chemistry: Use of ortho-Thioquinones and alpha,alpha'-Dioxothiones. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 120, pp. 339-340, ISSN:1042-6507

G. Capozzi; T. Becucci; S. Menichetti; C. Nativi (1997). Characterisation and reactivity of a ketodeoxypentose of natural origin. GAZZETTA CHIMICA ITALIANA, vol. 127, pp. 73-78, ISSN:0016-5603

G. Capozzi; C. Falciani; S. Menichetti; C. Nativi (1997). Selective Hydrolysis of Bicyclic Ortho Esters: Synthesis of Dithioacetals of Glyoxylic Acid Derivatives. SULFUR LETTERS, vol. 20, pp. 173-177, ISSN:0278-6117

G. Capozzi; A. Corti; S. Menichetti; C. Nativi (1997). alpha-Oxosulfines: New Generation Methods and Reactivity. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 120, pp. 317-318, ISSN:1042-6507

G. Capozzi; P. Fratini; S. Menichetti; C. Nativi (1996). alpha-Oxosulfines Part 1: Reactivity of alpha-Oxosulfines Obtained From Retro Diels-Alder Reaction of 1,4-Oxathiin-S-Oxides. TETRAHEDRON, vol. 52, pp. 12233-12246, ISSN:0040-4020

G. Capozzi; C. Falciani; S. Menichetti; C. Nativi (1996). Phthalimidesulfenyl Chloride Part 10. A Synthetic Equivalent of HS+ and +S-S+ Species in Electrophilic Aromatic Substitutions. GAZZETTA CHIMICA ITALIANA, vol. 126, pp. 227-232, ISSN:0016-5603

G. Capozzi; P. Fratini; S. Menichetti; C. Nativi (1996). alpha-Oxosulfines Part 2: The First Example of Ortho-thioquinones-S-Oxides. TETRAHEDRON, vol. 52, pp. 12247-12252, ISSN:0040-4020

G. Capozzi; A. Dios; R. Franck; A. Geer; C. Marzabadi; S. Menichetti; C. Nativi; M. Tamarez (1996). The Cycloaddition Way to Glycosyl Transfer. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION IN ENGLISH, vol. 35, pp. 777-779, ISSN:0570-0833 DOI Accesso ONLINE all'editore

G. Capozzi; P. Fratini; S. Menichetti; C. Nativi (1995). Generation and Trapping of alpha,alpha'-Dioxosulfines from 1,4-Oxathiine-S-Oxides. TETRAHEDRON LETTERS, vol. 36, pp. 5089-5092, ISSN:0040-4039

G. Capozzi; C. Falciani; R. Franck; S. Menichetti; C. Nativi (1995). A Novel Stereo- and Regio-Controlled Synthesis of 2-Deoxy-alpha-O-Aryl Glucosides. TETRAHEDRON LETTERS, vol. 36, pp. 6755-6758, ISSN:0040-4039

G. Capozzi; R. Franck; M. Mattioli; S. Menichetti; C. Nativi; G. Valle (1995). Phthalimidesulfenyl Chloride Part 9. A Simple Access to alpha,alpha'-Dioxothiones, a New Class of Bis-Heterodienes. Synthesis of 1,4-Oxathiin Systems. JOURNAL OF ORGANIC CHEMISTRY, vol. 60, pp. 6416-6426, ISSN:0022-3263

G. Capozzi; S. Menichetti; C. Nativi; M. C. Simonti (1994). Phthalimidesulfenyl Chloride Part 8. Reaction with Activated Arenes: The First Example of Ortho-Thioquinone Generation. TETRAHEDRON LETTERS, vol. 35, pp. 9451-9454, ISSN:0040-4039

G. Capozzi; F. De Sio; C. Nativi; S. Menichetti; P.L. Pacini (1994). Phthalimidesulfenyl Chloride Part 7. Synthesis of 2-Substituted-3-Chloro Benzo[b]Thiophenes and Related Heteroaromatics. SYNTHESIS, vol. -, pp. 521-525, ISSN:0039-7881

G. Capozzi; S. Menichetti; C. Nativi (1994). Cyclic Sulfides" in The Reactivity of Functional Groups: The Syntheses of Sulfones Sulfoxides and Cyclic Sulfides. New York: S. Patai, Z. Rappoport

G. Capozzi; S. Menichetti; C. Nativi (1994). Reactivity of alpha,alpha'-dioxothiones. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 75, pp. 356-360, ISSN:1042-6507 DOI

G. Capozzi; S. Menichetti; C. Nativi; R. Seraglia; P. Traldi (1993). Comparison Between the Mass Spectrometric Behaviour and Condensed phase Reactivity of Products of Addition of Phthalimidesulphenyl Chloride to Aryl Acetylenes. OMS, ORGANIC MASS SPECTROMETRY, vol. 28, pp. 101-106, ISSN:0030-493X

G. Capozzi; C. Nativi; S. Menichetti; A. Rosi; R. Franck (1993). Phthalimidesulfenyl Chloride Part 6. The First Example of an alpha-Oxothione Acting as Heterodiene: Synthesis of 2,3-Dihydro-1,4-Oxathiines. TETRAHEDRON LETTERS, vol. 34, pp. 4253-4257, ISSN:0040-4039

G. Capozzi; C. Nativi; S. Menichetti; A. Rosi; G. Valle (1992). Phthalimidesulfenyl Chloride. Part 5. Reaction with enolizable carbonyl compounds and synthesis of functionalized thiones. TETRAHEDRON, vol. 48, pp. 9023-9032, ISSN:0040-4020

E. Busi; G. Capozzi; S. Menichetti; C. Nativi (1992). Phtahlimidosulfenyl Chloride. Part 3. A novel and efficient synthesis of alkynyl vinyl sulphides. SYNTHESIS, vol. -, pp. 643-645, ISSN:0039-7881

G. Capozzi; L. Gori; S. Menichetti; C. Nativi (1992). Phthalimidesulfenyl Chloride. Part 4. Addition to Acetylenes and Synthetic Utilization of their Adducts. JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. I, vol. -, pp. 1923-1928, ISSN:0300-922X DOI

C. Nativi; N. Ravida’; A. Ricci; G. Seconi; M. Taddei (1991). C-Centered Optically Active Organosilanes. A Rational Approach to an Efficient Silylated Chiral Auxiliary. JOURNAL OF ORGANIC CHEMISTRY, vol. 56, pp. 1951-1955, ISSN:0022-3263

C. Nativi; E. Perrotta; A. Ricci; M. Taddei (1991). Synthetic Approaches Towards 4-(Silylmethyl)-2-Azetidinones. TETRAHEDRON LETTERS, vol. =, pp. 2265-2268, ISSN:0040-4039

C. Nativi; G. Palio; M. Taddei (1991). Acyclic Stereoselection in the Reaction of Chiral Allylsilanes with Electrophiles. TETRAHEDRON LETTERS, vol. 32, pp. 1583-1586, ISSN:0040-4039

C. Nativi; A. Ricci; M. Taddei (1990). Synthesis of 4-(Trimethylsilyl) and 4-(Tributylstannyl)-2-azetidinones and some of their Applications to -Lactam Chemistry. TETRAHEDRON LETTERS, vol. 31, pp. 2637-2640, ISSN:0040-4039

C. Nativi; M. Taddei; A. Mann (1989). Stannyldienes, New Tools for Organic Synthesis. Preparation and Reactivity. TETRAHEDRON, vol. 45, pp. 1131-1144, ISSN:0040-4020

C. Nativi; J.L. Reymond; P. Vogel (1989). Acid Catalyzed Rearrangement of 3-Aza-8-oxatricyclo[3.2.1.0]octan-6-one Acetals. Stereoselective Total Synthesis of 3-Amino-3-deoxy-D-altrose and Derivatives. HELVETICA CHIMICA ACTA, vol. 72, pp. 882-891, ISSN:0018-019X

A. Mann; C. Nativi; M. Taddei (1988). Acetal-Initiated Cyclization of Allylsilanes to Highly Functionalized Piperidine Derivatives. TETRAHEDRON LETTERS, vol. 29, pp. 3247-3250, ISSN:0040-4039

C. Nativi; M. Taddei (1988). Some Observations on the Stereochemical and Regiochemical Outcome of Hydrostannylation of Substituted Propargyl Alcohols. JOURNAL OF ORGANIC CHEMISTRY, vol. 53, pp. 820-826, ISSN:0022-3263

C. Nativi; M. Taddei; A. Mann (1987). A Regioselective Synthesis of 2-Tributylstannyl-1,3-dienes. TETRAHEDRON LETTERS, vol. =, pp. 347-350, ISSN:0040-4039

C. Nativi; A. Ricci; M. Taddei (1987). A Simple Synthesis of 1-Trimethylsilyl-2,3-Dienes. TETRAHEDRON LETTERS, vol. 28, pp. 2751-2752, ISSN:0040-4039

Cristina NATIVI

Curriculum

Education :

- July 1987, Doctorate Degree in Chemistry (summa con laude), University of Florence, Italy
- 1987-1989, Fellowship at the University of Lausanne, Switzerland (Prof. P. Vogel - Naked sugars).
- 1993-1994, Post-doc at the University of Montreal, Canada (Prof. S. Hanessian - C-glycosidation)

Career:
- 1989-1991: Grant from CNR (National Research Council), University of Florence, Italy (Synthesis of silyl analogues of beta-lactams).
- 1991-2000: Assistant Professor, University of Florence, Italy (Sulfur-mediated stereoselective synthesis of deoxy glycosides).
- 2000-2005: Associate Professor, University of Florence, Italy.

- 2005- present : Full Professor, University of Florence, Italy

Main fields of research: Carbohydrate chemistry, Synthesis of oligosaccharides of biological relevance, Sulfur chemistry, Molecular Recognition of Carbohydrate, Stereoselective Synthesis and glycosyl-containing inhibitors of Matrix Metallo Proteinases (MMPs). Saccharidic immunostiomulants and therapeutic vaccines. Bioactive multivalent glycosides.

Grant:

MiUR – Progetti PRIN di interesse Nazionale 2004-06, 2006-08, 2008-2010, 2010-2013 and 2015-2019.

Regione Toscana - 2006

ITT (Istituto Toscano Tumori) –2008-2009 and 2009-2010

Fondazione Cassa di Risparmio di Firenze – 2006-2008, 2007-2009, 2008-2009, 2009-2010, 2011-2012, 2012-2013, 2015 and 2018-2020.

Bilateral project (Galileo project IT-FR) – 2009 and 2012 (Florence-Grenoble)

AIRC 2012-2014 and 2021- now (Associazione Italiana Ricerca sul Cancro)

She is co-authors of more than 190 publications on international journals, 9 book-chapters, 5 licenced patents and more than 50 oral communications. One of the paptent is currently object of industrial licence.

She has been member of the Management Committee of the COST project titled “Multivalent Glycosystem for Nanoscience”- COST Action CM1102 and currently is in the Management Committee of the COST Action 16231 titled “Eu Network of Vaccines Adjuvants”. Co-applicant of the new granted COST Action EUROSTOP (starting on Oct. 2022). She is the coordinator of the Italian Interdivisional Group of Carbohydrate, she is in the organizing committee of the National Meeting and School of Carbohydrate Chemistry and was member the scientific committee of FiorGen (Pharmaco-genomic Foundation), “Leonardo da Vinci BioBank” and is member of the scientific committee of the spin-off GiottoBiotech. She is member of the Editorial Advisory Board of the Current of Organic Synthesis (COS), Global Vaccine & Immunology and Molecules. In 2007, 2009 and 2010 she has been involved in the Erasmus Intensive program “SYNAPS: Synthesis and retrosynthesis in the chemistry of Natural products” delivering lectures on biological role of carbohydrates and stereoselective synthesis of mono and oligosaccharides. She is in the teaching board of the International PhD School of the University of Florence on Structural Biology. She is a grant applications’ reviewer for MiUR (Ministero for University and Reaserch, Italy), for the Israel Science Foundationand for l’Agence de Recherche, France.

She has been the delegate for the University of Florence in the scientific committee of the Italian academic consortium CINMPIS. Since 2023 Titular Member of IUPAC Division III.

She is member of the commission for the Communication and Public Engagement of the University of Florence and of CSAVRI (UniFi).

In 2019 she has been awarded by the Italian Society of Chemistry with the Life Science Research Prize and in 2020 selected by ACS Omega journal as "Women in Science" fellow.