_SKIPNAVIGATION
ITA |
ENG
Personale
Recapiti
Pagina Cercachi
Italiano
Curriculum
Pubblicazioni
Insegnamenti
Alessandro Maria VANNUCCHI
Ruolo attuale:
Professore Ordinario
SSD:
MEDS-09/B - Malattie del sangue
Afferenza organizzativa:
Dipartimento di Medicina Sperimentale e Clinica
Recapiti
0554277688
a.vannucchi(AT)unifi.it
Alessandro Maria VANNUCCHI
Curriculum
Titoli di studio
1976-Diploma di Maturità Classica, Pistoia, con il massimo dei voti
29/12/1982-Consegue la Laurea in Medicina e Chirurgia presso l’Università degli Studi di Firenze, con il punteggio di 110/110 e Lode, discutendo la tesi “Studio sulla produzione di trombossano A2 piastrinico nelle sindromi mieloproliferative”, pubblicata in J. Nuclear Medicine and Allied Sciences, 1983; 27:206
1983-Consegue l’abilitazione all’esercizio della professione di medico-chirurgo presso l’Università degli Studi di Firenze; da questa data, iscritto all’Ordine dei Medici della provincia di Pistoia prima e di Firenze attualmente
Specializzazioni
09/07/1985
Consegue la Specializzazione in Ematologia generale (clinica e di laboratorio) presso l’Università degli Studi di Firenze, con il punteggio di 70/70 e Lode, discutendo la tesi “Studio sulla crescita in vitro di colonie megacariocitarie in pazienti con disordini mieloproliferativi”, pubblicata in American Journal of Hematology, 1987; 25:371
Borse di studio, premi e riconoscimenti
1983-1985
Vincitore del concorso pubblico, indetto dal Ministero della Pubblica Istruzione, per l’attribuzione di una borsa di studio triennale (1983-1985) per la frequenza della Scuola di Specializzazione in Ematologia della Università di Firenze
1987-1989
Ottiene una borsa di studio della Associazione Italiana per la lotta contro le Leucemie (AIL) per studi sulla emopoiesi normale e patologica, con particolare interesse per le malattie mieloproliferative croniche e le leucemie mieloidi acute.
1994
Riceve il Premio SIBIOC, della Società Italiana di Biochimica Clinica, per una comunicazione orale presentata, in collaborazione con altri Autori, al 26° Congresso Nazionale della Società Italiana di Biochimica Clinica.
2001
Ottiene il Premio Associazione Italiana per le Leucemie per la migliore comunicazione scientifica come coautore, presentata in Sessione plenaria al 38° Congresso Nazionale della SIE, Firenze
1997
Nomina a Honorary Member della New England Cancer Society per “gli studi condotti su aspetti clinico-biologici del trapianto di midollo osseo applicato alle malattie tumorali”
2006-Selezione per Plenary Scientific Session al 48th Annual Meeting of the American Society of Hematology, Orlando, USA
2006
2007
2008-Press Conference in occasione del 48th Annual Meeting of the American Society of Hematology
Lettura Sessione Educazionale al 48th Annual Meeting of the American Society of Hematology, “Thrombocytosis and thrombosis”
Lettura Sessione Educazionale al 13 Annual Meeting European Society of Hematology, “Stratified management of essential thrombocythemia and polycythemia vera”
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Brevetti
2007
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E’ primo inventore, in collaborazione con i Dr. Guglielmelli, Ponziani e Pancrazzi, del Brevetto per Invenzione domanda depositata FI2007A000274, relativo ad “Analisi mutazionale delle malattie mieloproliferative croniche”, descrivente una nuova tecnologia per la determinazione quantitativa delle mutazioni a carico del gene MPL nelle malattie mieloproliferative croniche
• Posizioni professionali ricoperte
2/05/1990-
29/12/1993-Vincitore del concorso per Assistente di ruolo presso la Divisione di Ematologia, Ospedale di Careggi, Firenze, che ricopre dal 2 maggio 1990. Dal momento dell’assunzione in ruolo, ha prestato servizio in maniera continuativa presso il Servizio Trapianti di Midollo Osseo della Divisione di Ematologia, diretta dal Prof. Pierluigi Rossi Ferrini
30/12/1993-
31/12/1994-Vincitore del concorso per la qualifica di Aiuto Corresponsabile ospedaliero presso la stessa Divisione di Ematologia di Firenze
1.01.1995-Attribuzione della qualifica di Dirigente di I° livello, fascia A
02/02/1998-
a tutt’oggi-Attribuzione dell’incarico di Responsabile del settore organizzativo-gestionale del Laboratorio di Ematologia, con anche la responsabilità di sostituire temporaneamente il Direttore della U.O. di Ematologia. Incarico che riveste tutt’ora
01/11/2002-Viene chiamato a ricoprire il ruolo di Professore di II fascia nel settore disciplinare MED15 dalla Facoltà di Medicina e Chirurgia della Università degli Studi di Firenze, dopo avere ottenuto l’idoneità a professore Associato, settore disciplinare MED15 (Malattie del Sangue) nel 2002 (decreto Rettorale n. 5067 del 2 gennaio 2002) presso l’Università Cattolica del Sacro Cuore, Roma, con il seguente Giudizio Collegiale: “Il candidato ha svolto attività didattica di insegnamento sia nell’ambito della Scuola di Specializzazione in Ematologia sia nel Corso di Laurea in Medicina e Chirurgia, ed ha prestato servizio in Università come Professore a contratto. Ha svolto ottima attività di ricerca, congrua al raggruppamento disciplinare F07G/MED15, ed ha prestato attività clinico-assistenziale in una struttura ematologica. La discussione sui titoli è stata convincente e la prova didattica è risultata di eccellente livello.”
01/11/2005-
a tutt’oggi-Associato Confermato nella Facoltà di Medicina e Chirurgia della Università di Firenze per il settore scientifico-disciplinare MED/15 con Decreto Rettorale 313 sel 20/06/2006, ruolo che riveste attualmente
Esperienze di Ricerca all’estero
03/1987-Observer presso il Laboratorio Investigative Cytology , Department of Pathology, del Memorial Sloan-Kettering Cancer Center, New York, diretto dal Dr. Myron R. Melaned, ove ha collaborato a ricerche su modelli matematici di analisi della cinetica di piastrine radiomarcate e su aspetti della differenziazione e caratterizzazione citofluorimetrica di megacariociti umani e murini purificati
25/10/1988-11/11/1988-Visiting Scientist presso la Division of Haematology del United Medical and Dental Schools of Guy’s and St. Thomas Hospital, University of London, , diretto dal Dr. Thomas C. Pearson, ove si è recato dietro invito del Prof. S. Eridani, responsabile del Laboratorio di Ematologia sperimentale, per svolgere ricerche su originali metodiche di analisi della crescita megacariocitaria in vitro, applicata ai disordini delle sindromi mieloproliferative croniche
01/05/1995-
20/10/1995-Visiting Scientist presso il Laboratory of Hematopoietic Growth Factors del New York Blood Center, New York, diretto dalla Dr. Anna Rita Migliaccio, sotto la supervisione del Dr. John Adamson, ove ha condotto ricerche sulla purificazione e caratterizzazione molecolare di cellule staminali emopoietiche murine ed umane, in particolare su aspetti del differenziamento eritroide; ha inoltre approfondito tematiche relative alla caratterizzazione di cellule staminali umane ottenute da sangue di cordone ombelicale, a fine trapiantologico
Attività di ricerca sperimentale
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I principali campi di interesse attuali della ricerca sperimentale sono rappresentati dallo studio:
di meccanismi di regolazione della eritropoiesi e della megacariocitopoiesi normale
del fattore di trascrizione GATA-1 nella normale emopoiesi
del modello murino GATA-1low come modello di mielofibrosi umana
di alterazioni molecolari nelle neoplasie mieloproliferative, e delle correlazioni tra genotipo e fenotipo
di marcatori molecolari nelle leucemie acute mieloidi
di profili di espressione genica nelle neoplasie mieloproliferative, e del loro possibile ruolo come marcatori di malattia e di risposta alla terapia
di farmaci con attività selettiva nelle neoplasie mieloproliferative
Attività di ricerca clinica
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dal 2008--Ha partecipato/partecipa, in qualità di investigatore, a studi clinici controllati, condotti secondo le Good Clinical Practices, sia monocentrici che multicentrici, tra i quali i più recenti:
Studio osservazionale Excell di confronto tra Anagrelide e Idrossiurea in pazienti con trombocitemia essenziale ad alto rischio
Studio del Myeloproliferative Disorders Research Consortium- MPD-RC 102, “An open-label phase ? study of Velcade for injection in subjects with myelofibrosis with myeloid metaplasia”
Studio del Myeloproliferative Disorders Research Consortium- MPD-RC 106, “Research Tisseu Bank”
Studio multicentrico GIMEMA CYTO-PV, “Studio clinico controllato per valutare l’efficacia di terapie citoriduttive a diversa intensità nel prevenire gli eventi cardiovascolari in pazienti affetti da Polcitiemia Vera”
E’ coordinatore nazionale dello studio GIMEMA “CYTO-PV, Substudy CY-S1, “Prospective evaluation of the predicitve role of JAK2V617F allele burden on clinical outcome in patients with polycythemia vera”
E’ coordinatore nazionale dello studio multicentrico, finanziato da AIFA, “A phase1/2 trial of RAD001 in patients with myelofibrosis”
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Pubblicazioni
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L’attività scientifica del Prof. A.M. Vannucchi è testimoniata dalle pubblicazioni, riportate nell’allegato Elenco delle Pubblicazioni, che possono essere così suddivise:
-Articoli pubblicati in riviste internazionali n. 135
Capitoli o sezioni di libro: n. 29
Comunicazioni per extenso a congressi nazionali e internazionali:
64
Comunicazioni a congressi internazionali: n. 169
Comunicazioni a congressi nazionali: n. 125
Relativamente agli articoli pubblicati in riviste internazionali:
46 articoli come primo autore
17 articoli come ultimo autore
• Il valore Impact Factor (calcolato sui parametri IF 2007), relativamente agli articoli pubblicati in riviste internazionali, è il seguente:
I.F. totale : 682.98
I.F. medio: 5.69
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Finanziamenti per la ricerca
(elenco parziale)
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1997-1998-Responsabile di un progetto finanziato nell’ambito del Progetto finalizzato “30 ore per la vita” della Associazione Italiana per le Leucemie, per la “caratterizzazione di cellule di eritroleucemia umana”
2002-2004-Responsabile di Unità Operativa nell’ambito dei Progetti di ricerca finalizzata 2001, Ministero Italiano della sanità, “On/off regulation between proliferation and differentiation of hematopoietic stem cell” , progetto dal titolo “The GATA-1low mutant as a model for pathogenesis of human myelofibrosis”
2003-2005-Coordinatore Nazionale di un Programma “Mechanism underlying ex vivo expansion of cord blood hematopoietic stem cells and their proper differentiation toward the megakaryocyte phenotype” nell’ambito del “Progetto Nazionale sulle Cellule staminali”, Ministero della Sanità
2003-Responsabile di un Progetto AIRC dal titolo “Role of GATA-1 transcription factor in the pathogenesis of idiopathic myelofibrosis”
2004-Responsabile di un Progetto AIRC dal titolo “Gene expression profiling of idiopathic myelofibrosis cells: an approach to molecular mechanisms of disease”
2003-2004-Responsabile di Unità Operativa nell’ambito di un finanziamento MIUR, COFIN 2003-4, “Ph-negative chronic myeloproliferative disorders: biological and molecular aspects, diagnosis and complication prevention”, progetto dal titolo “Role of transcription factors GATA1/FOG1 in the abnormal regulation of megakaryocytopoiesis in the pathogenesis of chronic myeloproliferative disorders”.
2005-2007-Responsabile di un Progetto triennale AIRC dal titolo “A molecular approach to the pathogenesis and diagnosis of idiopathic myelofibrosis”
2005-2006-Responsabile di un Progetto finanziato dalla Fondazione Cassa di Risparmio (Firenze) (2005, 2006) “Development of innovative diagnostic approaches in patients with idiopathic myelofibrosis”
2006-2008-Responsabile di Unità Operativa nell’ambito di un Progetto di Ricerca Sanitaria Finalizzata del Ministero Italiano della Sanità, dal titolo “Study of the hemangioblast in idiopathic myelofibrosis”
2007-2008
2007-2009-Responsabile di Unità Operativa nell’ambito di un finanziamento MIUR, COFIN 2007-8, “Genomic and functional analysis of hematopoietic cells in chronic myeloproliferative disorders”, programma dal titolo “Analysis of expression profiling in myelofibrosis: pathogenetic and diagnostic implications”
Responsabile nazionale di un progetto multicentrico finanziato da AIFA, “A phase1/2 trial of RAD001 in patients with myelofibrosis”
2008-2009-Responsabile di un Progetto di ricerca finanziato dall’Istituto Toscano Tumori, “Novel therapeutic targets in the Philadelphia-negative chronic myeloproliferative disorders”
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Partecipazione a gruppi di studio nazionali ed internazionali
-Membro e responsabile locale del Registro Italiano della Mielofibrosi, http://rimm.it
-Membro e responsabile locale del Registro Italiano della Trombocitemia http://rit.it
Membro del International Working Group for Myelofibrosis Research and Treatment, Houston, USA,
http://www.mpdinfo.org/IWG_MRT/membership_roster.html
-Membro del Myeloproliferative Disorder Research Consortium, Mount Sinai Hospital, New York, http://mpd-rc.negrisud.it
Membro del Comitato Direttivo del Working Party delle Malattie mieloproliferative croniche Ph’-negative del GIMEMA
Membro del WP 9 (chronic Myeloproliferative disorders) del European LeukemiaNet
Attività didattica
1991-1993-Tiene il Corso di “Biologia Molecolare” alla Scuola per Tecnici di Laboratorio Biomedico, Firenze
1994-1995-Tiene il Corso di “Patologia Generale” alla Scuola per Tecnici di Laboratorio Biomedico, Firenze
dal 1992 al 2002
Professore a contratto (titolare del Corso Integrativo “Fisiopatologia del sangue e degli organi emopoietici”) presso la Scuola di Specializzazione in Genetica Medica della Università degli Studi di Firenze
Dal 1994 al 1999-Professore a contratto (titolare del Corso Integrativo “Fisiopatologia clinica e inquadramento nosografico della piastrinopoiesi”) presso la Scuola di Specializzazione in Ematologia dell’Università degli Studi di Firenze
Dal 2000 al 2002-Professore a contratto (Corso “Malattie del sangue. Area: Trapianto di cellule staminali emopoietiche”) presso la Scuola di Specializzazione in Ematologia Generale dell’Università degli Studi di Firenze
Dal 2000 al 2002-Professore a contratto (Corso “Malattie del sangue. Area: Laboratorio di Ematologia diagnostico”) presso la Scuola di Specializzazione in Ematologia Generale dell’Università degli Studi di Firenze
Dal 1999 al 2002-Professore a contratto del Corso “Immunologia” presso la Scuola di Specializzazione in Farmacologia Ospedaliera Università di Firenze
AA 2000-2001-Professore a contratto (settore F07G) per Malattie del Sangue nel Corso Integrato di Specialità Medico Chirurgiche I nel corso di Laurea in Medicina e Chirurgia, Università degli Studi di Firenze
2002-
a tutt’oggi-Insegna Malattie del Sangue nel Corso Integrato di Specialità Medico Chirurgiche I nel corso di Laurea in Medicina e Chirurgia, Università degli Studi di Firenze
2003-
a tutt’oggi-Co-titolare del Corso di Tecniche Diagnostiche in Ematologia al Corso di Laurea triennale in Biotecnologie Mediche, Università degli Studi di Firenze
2005-
a tutt’oggi-Titolare del Corso integrato MED/15 in Diagnostica Oncologia al Corso di Laurea specialistica in Biotecnologie Mediche, Percorso Medico-Diagnostico, Università degli Studi di Firenze
2002-
a tutt’oggi-Insegna alla Scuola di Specializzazione in Ematologia, Università degli Studi di Firenze, Corso di malattie della piastrinopoiesi, Corso di Fisopatologia e clinica delle malattie mieloproliferative croniche
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2002-
a tutt’oggi-Relatore e correlatore di Tesi di Laurea in Medicina e Chirurgia, Biotecnologie Mediche (corso triennale), e Tesi di Specializzazione in Malattie del Sangue
2004-
a tutt’oggi-Membro del Consiglio dei Docenti del Dottorato in Oncologia Clinica e Sperimentale della Facoltà di Medicina e Chirurgia della Università di Firenze
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Attivita’ editoriali e organizzative
1991-Traduttore della edizione italiana del testo “Hematology” di W.J. Williams, Mc Graw Hill, edizione del 1991 (capitoli 126-146)
1993-Editore (con A. Grossi & P. Rossi Ferrini) del volume “Disorders of erythropoiesis: therapeutical implications”. Wichtig Ed., Milano, di cui ha curato anche la Prefazione
1993-Revisore per il 34° Congresso Nazionale della Società Italiana di Ematologia
1994-Traduttore della edizione italiana del testo “Malattie della emostasi e della trombosi” di W.E. Hathaway & S.H. Goodnight, Mac Graw Hill
1994-Editore (con P. Rossi Ferrini) del volume “Malattie della emostasi e della trombosi” di W.E. Hathaway & S.H. Goodnight, Mac Graw Hill
1994-Tiene la Segreteria Scientifica del Congresso “Alterazioni della eritropoiesi: implicazioni terapeutiche”, Firenze
2001-Membro del Comitato Organizzatore Locale del 38° Congresso Nazionale della Società Italiana di Ematologia
2003-
Chairman del Symposium on Current Perspectives in Myeloproliferative Disorders, XVIIth Meeting of the International Society of Haematology, Graz, 9 settembre
2003-Moderatore all’Incontro su “Interferone in Ematologia”, Firenze
2004-Organizzatore e Moderatore dell’Incontro Discutiamone Insieme “I fattori trascrizionali che regolano l’emopoiesi normale e patologica”, Firenze
2005-Scientific Committe del Workshop of the European Network on Myelofibrosis-EUMNET, Firenze, 23-24 settembre
2006-Scientific Committe del II International Florence Meeting in Hematology “Focus on Ph’-negative chronic myeloproliferative disorders”, Firenze
2007-Revisore per il 49th Annual Meeting of the American Society of Hematology, ASH, Atlanta
2008-Revisore per il 13th Annual Meeting of the European Hematology Association-EHA, Copenhagen
2008-Revisore per il 34th Annual Meeting of the European Group for Blood and Bone Marrow Transplantation-EBMT, Firenze
2007-Responsabile della creazione del sito web della UF di Ematologia del Dipartimento di Area critica della Facoltà di medicina e Chirurgia della Università di Firenze, www.ematologiafirenze.com
2008-2010-Fa parte del Board Editoriale di Haematologica per il trienno 2008-2010
Dal 2000
a tutt’oggi-Effettua regolarmente attività di Revisore per riviste di argomento ematologico quali Blood, Leukemia, Haematologica, British Journal of Haematology, Stem Cells, Leukemia Research, Annals of Hematology, International Journal of Clinical and Laboratory Hematology
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Attività clinica
Dal momento dell’ assunzione a ruolo presso la Divisione di Ematologia dell’Ospedale di Careggi, Università degli Studi di Firenze, ha operato in maniera continuativa fino al 2006 presso il Servizio Trapianti di Midollo Osseo, partecipando all’attività di programmazione, esecuzione, e follow-up di tutti i trapianti (autologo, da midollo e da sangue periferico, allogenico, da donatore familiare e non familiare, e da cordone ombelicale) effettuati dal Centro, compresa l’attività di sala operatoria per espianto di midollo da pazienti e donatori, e l’attività di monitoraggio ambulatoriale dei pazienti trapiantati.
Ha inoltre acquisito particolare esperienza nel campo delle malattie mieloproliferative croniche, effettuando attività di diagnostica e monitoraggio terapeutico ambulatoriale presso l’Ambulatorio per pazienti esterni della Divisione di Ematologia di Firenze. Dal Settembre 2006, svolge la propria attività assistenziale nell’Ambulatorio per esterni della SODc di Ematologia della Azienda Ospedaliera-Universitaria Careggi, occupandosi della diagnosi, terapia e follow-up delle diverse patologie ematologiche, ma continuando ad occuparsi in particolare della malattie mieloproliferative croniche. A tal riguardo, ha sviluppato un Percorso Diagnostico Integrato per pazienti con Malattie Mieloproliferative croniche.
Si è interessato della messa a punto di alcune tecniche laboratoristiche utilizzate a scopo diagnostico nei pazienti emopatici; tra queste, lo studio della cinetica piastrinica con piastrine radiomarcate; lo studio della crescita spontanea in vitro di progenitori eritroidi e megacariocitari; la ricerca, mediante tecniche di biologia molecolare, del riarrangiamento genico bcl-1, bcl-2, bcl-6 per pazienti con linfoma non-Hodgkin; una metodica di indagine molecolare (ricerca del mRNA per la citocheratina-19) per la determinazione di micrometastasi midollari in pazienti con neoplasia mammaria avviate alla procedura autotrapiantologica; la determinazione, con tecnica molecolare, del grado di chimerismo in pazienti sottoposti a trapianto allogenico di cellule staminali, in particolare con protocolli non-mieloablativi; la definizione del polimorfismo di geni per citochine, in studi volti a definirne il rapporto con la comparsa di complicazioni post-trapiantologiche. Negli ultimi anni, ha coordinato nell’ambito del laboratorio di Diagnostica Molecolare delle Malattie Mieloproliferative croniche, di cui è responsabile, lo sviluppo di metodologie molecolari avanzate per la ricerca e la quantificazione delle mutazioni del gene JAK2, MPL, cKIT, GATA-1, del riarrangiamento PDGFRalpha-FIPL1, nonchè delle più frequenti anomalie molecolari in apzienti con leucemia Mieloide Acuta, quali le duplicazioni del gene FLT3, le mutazioni di NPM1,
In qualità di Responsabile del settore organizzativo-gestionale del Laboratorio di Ematologia, dal 1998 ha curato la organizzazione funzionale di questo stesso.
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Appartenenza a società scientifiche
Società Italiana di Ematologia (SIE)
Società Italiana di Ematologia Sperimentale (SIES)
European Hematology Association (EHA)
American Society of Hematology (ASH)
European Cooperative Group for Bone Marrow Transplantation (EBMT)
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Relazioni e Seminari ad invito
Ha tenuto le seguenti letture ad invito (lista parziale, ultimi 5 anni)
2002-Relazione “Valutazione molecolare dell’infiltrazione midollare nei linfomi follicolari e problemi clinici ad essa correlati” . Meeting “Linfomi follicolari. Un workshop per tante domande”, Firenze, 12 aprile 2002
-Relazione “Biologia molecolare” al Corso Residenziale sui Linfomi, Firenze 6 maggio
2003-Relazione “GATA-1 e mielofibrosi: dal modello animale all’uomo”, Workshop “Il registro Italiano della Mielofibrosi, Pavia 9 maggio
-Relazione “Fisiopatologia dell’eritropoiesi”, Meeting “L’anemia nel periodo perioperatorio”, Firenze 17 maggio
-Relazione “Impaired GATA-1 expression and myelofibrosis in an animal model”. (EHA meeting,). Satellite Symposium “New perspectives in the molecular pathogenesis and treatment of myeloproliferative diseases. Scientific meeting of the European Working Group on Myeloproliferative Diseases”. Lyon, 12 giugno
-Relazione “Clinical aspects of myelofibrosis and GATA-1 mutation”, Symposium on Current Perspectives in Myeloproliferative Disorders, XVIIth Meeting of the International Society of Haematology, Graz, 9 settembre
-Relazione “Terapia cellulare dell’infezione da CMV”, Simposio “Infezioni virali nel paziente trapiantato”, Modena 15 settembre
-Relazione “Insights into the role of GATA-1 in the pathogenesis of myelofibrosis”. 2nd International Congress “Myeloproliferative diseases and Myelodysplastic syndromes”, New York, 16-18 ottobre
-Relazione “Linfomi non-Hodgkin follicolari: La biologia Molecolare”. Incontri FirenzEmatologia, Dicembre 1
2004-Relazione “Regolazione trascrizionale della megacariocitopoiesi”, Discutiamone Insieme SIES, Firenze 24 giugno
-Lettura “Regolazione della eritropoiesi”, VIII Congresso Nazionale SIES, Pavia 15 settembre
-Relazione “Ruolo della biologia molecolare nel monitoraggio dei linfomi”, Corso di Aggiornamento “Progressi nella diagnosi e nel trattamento dei linfomi non-Hodgkin”, Firenze 25 settembre
-Lettura “Impiego della eritropoietina nella terapia delle anemie”, XXXVI Convegno Nazionale di Studi di medicina Trasfusionale, Firenze 3 ottobre
2005-Relazione “Eritro e megacariocitopoiesi nella mielofibrosi idiopatica”, Corso Aggiornementi teorico-pratici in Ematologia, Bologna 22 febbraio
-Lettura “Regolazione dell’eritropoiesi”, 3 Congresso Nazionale della Società Italiana di Citometria Clinica e Sperimentale, Palermo 13 aprile
-Relazione “Fisiologia dell’eritropoiesi”, Stage in Ematologia sulle Sindromi Mielodisplastiche, Blogna 9 maggio
-Relazione “Molecula profiling of hematopoietic stem cells in idiopathic myelofibrosis”, International Symposium on Malignant Stem Cells in Idiopathic Myelofibrosis, Firenze 23 settembre
2006-Relazione “Applicazioni del Bortezomib nella mielofibrosi”, Simposio “L’inibitore del proteasoma nelle neoplasie ematologiche”, Firenze 31 marzo
-Relazione “Fisiologia della eritropoiesi”, Corso teorico-pratico su Le anemie refrattarie, Bologna 8 maggio
-Relazione “La mutazione JAK2V617F nelle sindormi mieloproliferative croniche”, Simposio “Siena 1996-2006: 10 anni di progressi diagnostici e terapeutici”, Siena 19 maggio
-Lettura “Molecular markers in idiopathic myelofibrosis”, European School of Haematology, Madeira Portugal, 16 settembre
-Lettura “Molecular markers of the chronic myeloproliferative disorders” al II International Florence Meeting on Ph’-negative chronic myeloproliferative disorders, Firenze 27 ottobre
2007-Relazione “Correlazione genotipo-fenotipo nelle sindormi mieloproliferative croniche JAK2 positive”, Discutiamone Insieme della SIES, aprile 12
-Relazione “La mutazione di JAK2 nelle malattie mieloproliferative croniche”, Corso Residenziale Argomenti di Ematologia Pratica, Bergamo 25 giugno
-Relazione “Genetic and epigenetic events in the pathogenesis of myelofibrosis”, II Workshop of the Italian registry of Myelofibrosis, Pavia 29 giugno
-Relazione “Genotype and clinical phenotype”, Focus on Myeloproliferative and Myelodysplastic syndromes, Bergamo 21 settembre
-Relazione “Biologia molecolare delle malattie mieloproliferative croniche Ph-negative tipiche”, Meeting Educazionale del 41° Congresso Nazionale della SIE, Bologna 17 ottobre
-Relazione “Bortezomib e mielofibrosi”, Meeting su Terapie innovative del
Mieloma Multiplo, Siena 26 ottobre
-Relazione “Thrombocytosis and thrombosis”, Education Program del 49th ASH Annual Meeting, Atlanta, 9-10 dicembre
-Relazione “Epigenetic regulation in MPDs”, Second Global CML Workshop: Did Dameshek get the Myeloproliferative disease right?, Puerto Rico, 12 dicembre
2008-Seminario “Genetica, epigenetica e patogenesi della mielofibrosi”, presso il Dipartimento di Medicina Clinica e Sperimentale della Università di Padova, su invito del prof. G. Semenzato, Pavia 27 marzo
Lettura “Meccanismi molecolari delle malattie mieloproliferative croniche”, Corso Biotecnologie e Medicina della Accademia delle Biotecnologie, Firenze 15 aprile 2008
Relazione “Clinical relevance of JAK2V617F mutational status and allele burden in myelofibrosis”; 1st Annual Scott Richards Symposium on Myelofibrosis, MD Anderson Cancer center, Houston, Tx
Seminario “Genotipo e fenotipo nelle malattei mieloproliferative croniche”, presso il Dip. Di Ematologia della Università di Bari, su invito della prof. G. Specchia, Bari 28 maggio 2008
Lettura “Stratified management of essential thrombocythemia and polycythemia vera”, Educational program, EHA meeting, Copenhagen
Alessandro Maria VANNUCCHI
Pubblicazioni
Legenda
Contributo su rivista |
Articolo su libro |
Libro |
Contributo in atti di convegno (proceeding) |
Brevetto |
Curatela |
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Tesi di Dottorato
Boldrini, Valentina; Vannucchi, Alessandro M.; Guglielmelli, Paola (2024). A safety evaluation of ruxolitinib for the treatment of polycythemia vera. EXPERT OPINION ON DRUG SAFETY, vol. 23, pp. 1-7, ISSN:1474-0338
DOI
Loscocco, Giuseppe G.; Rotunno, Giada; Mannelli, Francesco; Coltro, Giacomo; Gesullo, Francesca; Pancani, Fabiana; Signori, Leonardo; Maccari, Chiara; Esposito, Maria; Paoli, Chiara; Vannucchi, Alessandro M.; Guglielmelli, Paola (2024). The prognostic contribution of CBL, NRAS, KRAS, RUNX1, and TP53 mutations to mutation-enhanced international prognostic score systems (MIPSS70/plus/plus v2.0) for primary myelofibrosis. AMERICAN JOURNAL OF HEMATOLOGY, vol. 99, pp. 68-78, ISSN:0361-8609
DOI
Abenavoli, Elisabetta M; Linguanti, Flavia; Anichini, Matilde; Miele, Vittorio; Mungai, Francesco; Palazzo, Marianna; Nassi, Luca; Puccini, Benedetta; Romano, Ilaria; Sordi, Benedetta; Sciagra', Roberto; Simontacchi, Gabriele; Vannucchi, Alessandro M; Berti, Valentina (2024). Texture analysis of 18F-FDG PET/CT and CECT: Prediction of refractoriness of Hodgkin lymphoma with mediastinal bulk involvement. HEMATOLOGICAL ONCOLOGY, vol. 42, pp. 0-0, ISSN:1099-1069
DOI
Accesso ONLINE all'editore
Guglielmelli, Paola; Szuber, Natasha; Gangat, Naseema; Capecchi, Giulio; Maccari, Chiara; Harnois, Michaël; Karrar, Omer; Abdelmagid, Maymona; Balliu, Manjola; Nacca, Elena; Atanasio, Alessandro; Sestini, Ilaria; Désilets, Audrey; Loscocco, Giuseppe Gaetano; Rotunno, Giada; Busque, Lambert; Tefferi, Ayalew; Vannucchi, Alessandro Maria (2024). CALR mutation burden in essential thrombocythemia and disease outcome. BLOOD, vol. 143, pp. 1310-1314, ISSN:1528-0020
DOI
Antonioli, Elisabetta; Pilerci, Sofia; Attucci, Irene; Buda, Gabriele; Gozzetti, Alessandro; Candi, Veronica; Simonetti, Federico; Giudice, Maria Livia Del; Ciofini, Sara; Staderini, Michela; Grammatico, Sara; Buzzichelli, Alessandra; Messeri, Maria; Bocchia, Monica; Galimberti, Sara; Vannucchi, Alessandro M (2023). Carfilzomib, lenalidomide, and dexamethasone in relapsed refractory multiple myeloma: a prospective real-life experience of the Regional Tuscan Myeloma Network. FRONTIERS IN ONCOLOGY, vol. 13, pp. 0-0, ISSN:2234-943X
DOI
Barbui T, Vannucchi AM, De Stefano V, Carobbio A, Ghirardi A, Carioli G, Masciulli A, Rossi E, Ciceri F, Bonifacio M, Iurlo A, Palandri F, Benevolo G, Pane F, Ricco A, Carli G, Caramella M, Rapezzi D, Musolino C, Siragusa S, Rumi E, Patriarca A, Cascavilla N, Mora B, Cacciola E, Mannarelli C, Loscocco GG, Guglielmelli P, Gesullo F, Betti S, Lunghi F, Scaffidi L, Bucelli C, Vianelli N, Bellini M, Finazzi MC, Tognoni G, Rambaldi A (2023). Ropeginterferon versus Standard Therapy for Low-Risk Patients with Polycythemia Vera. NEJM EVIDENCE, pp. NEJM Evid 2023; 2 (6)-NEJM Evid 2023; 2 (6), ISSN:2766-5526
DOI
Atanasio, Alessandro; Bernabini, Sara; Consagra, Angela; Giotti, Irene; Carrai, Valentina; Pelo, Elisabetta; Vannucchi, Alessandro Maria (2023). Testing for rare types of Hereditary Hemochromatosis. A genetic study of two Italian families affected by early onset iron overload. INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, vol. 45, pp. 784-787, ISSN:1751-5521
DOI
Vannucchi, Alessandro Maria; Guglielmelli, Paola (2023). Acute Myocardial Infarction and Chronic Myeloproliferative Neoplasms: Friend and Enemy, Depending on Circumstances. JACC. CARDIOONCOLOGY, vol. 5, pp. 469-471, ISSN:2666-0873
DOI
Mora, Barbara; Maffioli, Margherita; Rumi, Elisa; Guglielmelli, Paola; Caramella, Marianna; Kuykendall, Andrew; Palandri, Francesca; Iurlo, Alessandra; De Stefano, Valerio; Kiladjian, Jean-Jacques; Elli, Elena M; Polverelli, Nicola; Gotlib, Jason; Albano, Francesco; Silver, Richard T; Benevolo, Giulia; Ross, David M; Devos, Timothy; Borsani, Oscar; Barbui, Tiziano; Porta, Matteo G Della; Bertù, Lorenza; Komrokji, Rami; Vannucchi, Alessandro M; Passamonti, Francesco (2023). Incidence of blast phase in myelofibrosis according to anemia severity. EJHAEM, vol. 4, pp. 679-689, ISSN:2688-6146
DOI
Karrar, Omer S; Abdelmagid, Maymona; Vannucchi, Alessandro M; Barbui, Tiziano; Tefferi, Ayalew; Gangat, Naseema (2023). ABO blood group type and risk of venous thrombosis in essential thrombocythemia. BRITISH JOURNAL OF HAEMATOLOGY, vol. 202, pp. 699-703, ISSN:0007-1048
DOI
Carobbio, Alessandra; Vannucchi, Alessandro Maria; Rumi, Elisa; De Stefano, Valerio; Rambaldi, Alessandro; Carli, Giuseppe; Randi, Maria Luigia; Gisslinger, Heinz; Passamonti, Francesco; Thiele, Juergen; Gangat, Naseema; Tefferi, Ayalew; Barbui, Tiziano (2023). Survival expectation after thrombosis and overt-myelofibrosis in essential thrombocythemia and prefibrotic myelofibrosis: a multistate model approach. BLOOD CANCER JOURNAL, vol. 13, pp. 1-3, ISSN:2044-5385
DOI
Mannelli, Francesco; Piccini, Matteo; Bencini, Sara; Gianfaldoni, Giacomo; Peruzzi, Benedetta; Caporale, Roberto; Scappini, Barbara; Fasano, Laura; Quinti, Elisa; Ciolli, Gaia; Pasquini, Andrea; Crupi, Francesca; Pilerci, Sofia; Pancani, Fabiana; Signori, Leonardo; Tarantino, Danilo; Maccari, Chiara; Paradiso, Vivian; Annunziato, Francesco; Guglielmelli, Paola; Vannucchi, Alessandro M (2023). Effect of age and treatment on predictive value of measurable residual disease: implications for clinical management of adult patients with acute myeloid leukemia. HAEMATOLOGICA, pp. 0-0, ISSN:1592-8721
DOI
Mesa, Ruben; Verstovsek, Srdan; Platzbecker, Uwe; Gupta, Vikas; Lavie, David; Giraldo, Pilar; Recher, Christian; Kiladjian, Jean-Jacques; Oh, Stephen T; Gerds, Aaron T; Devos, Timothy; Passamonti, Francesco; Vannucchi, Alessandro M; Egyed, Miklos; Lech-Maranda, Ewa; Pluta, Andrzej; Nilsson, Lars; Shimoda, Kazuya; McLornan, Donal; Kawashima, Jun; Klencke, Barbara; Huang, Mei; Strouse, Bryan; Harrison, Claire (2023). Clinical outcomes of patients with myelofibrosis after immediate transition to momelotinib from ruxolitinib. HAEMATOLOGICA, pp. 0-0, ISSN:1592-8721
DOI
Tefferi, Ayalew; Loscocco, Giuseppe G; Farrukh, Faiqa; Szuber, Natasha; Mannelli, Francesco; Pardanani, Animesh; Hanson, Curtis A; Ketterling, Rhett P; De Stefano, Valerio; Carobbio, Alessandra; Barbui, Tiziano; Guglielmelli, Paola; Gangat, Naseema; Vannucchi, Alessandro M (2023). A globally applicable "triple A" risk model for essential thrombocythemia based on Age, Absolute neutrophil count, and Absolute lymphocyte count. AMERICAN JOURNAL OF HEMATOLOGY, pp. 0-0, ISSN:0361-8609
DOI
Mascarenhas, John; Migliaccio, Anna Rita; Kosiorek, Heidi; Bhave, Rupali; Palmer, Jeanne; Kuykendall, Andrew; Mesa, Ruben; Rampal, Raajit K; Gerds, Aaron T; Yacoub, Abdulraheem; Pettit, Kristen; Talpaz, Moshe; Komrokji, Rami; Kremyanskaya, Marina; Gonzalez, Agapito; Fabris, Frank; Johnson, Kathryn; Dougherty, Mikaela; McGovern, Erin; Arango Ossa, Juan; Domenico, Dylan; Farnoud, Noushin; Weinberg, Rona Singer; Kong, Amy; Najfeld, Vesna; Vannucchi, Alessandro Maria; Arciprete, Francesca; Zingariello, Maria; Falchi, Mario; Salama, Mohamed E; Mead-Harvey, Carolyn; Dueck, Amylou; Varricchio, Lilian; Hoffman, Ronald (2023). A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis. CLINICAL CANCER RESEARCH, vol. 29, pp. 3622-3632, ISSN:1078-0432
DOI
Romagnoli, Simone; Bartalucci, Niccolò; Vannucchi, Alessandro Maria (2023). Resolving complex structural variants via nanopore sequencing. FRONTIERS IN GENETICS, vol. 14, pp. 0-0, ISSN:1664-8021
DOI
Paggi, Riccardo; Mariotti, Francesca; Mencarini, Jessica; Bresci, Silvia; Campolmi, Irene; Bartalesi, Filippo; Borchi, Beatrice; Nassi, Luca; Sordi, Benedetta; Vannucchi, Alessandro Maria; Bartoloni, Alessandro (2023). Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature. MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, vol. 15, pp. e2023028-0, ISSN:2035-3006
DOI
Accesso ONLINE all'editore
Shomali, William; Colucci, Philomena; George, Tracy I; Kiladjian, Jean-Jacques; Langford, Cheryl; Patel, Jay L; Reiter, Andreas; Vannucchi, Alessandro M; Gotlib, Jason (2023). Comprehensive response criteria for myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions: a proposal from the MLN International Working Group. LEUKEMIA, vol. 37, pp. 981-987, ISSN:0887-6924
DOI
Loscocco, Giuseppe G; Ascani, Stefano; Mannelli, Francesco; Zanelli, Magda; Rotunno, Giada; Santi, Raffaella; Vannucchi, Alessandro M (2023). Concomitant myeloproliferative neoplasm with eosinophilia, B and T cell lymphoblastic lymphoma/leukemia and mast cell proliferation driven by ZMYM2::FGFR1 rearrangement. AMERICAN JOURNAL OF HEMATOLOGY, pp. 1-4, ISSN:0361-8609
DOI
Gianelli, Umberto; Thiele, Jürgen; Orazi, Attilio; Gangat, Naseema; Vannucchi, Alessandro M; Tefferi, Ayalew; Kvasnicka, Hans Michael (2023). International Consensus Classification of myeloid and lymphoid neoplasms: myeloproliferative neoplasms. VIRCHOWS ARCHIV, vol. 482, pp. 53-68, ISSN:0945-6317
DOI
Guglielmelli, Paola; Maccari, Chiara; Sordi, Benedetta; Balliu, Manjola; Atanasio, Alessandro; Mannarelli, Carmela; Capecchi, Giulio; Sestini, Ilaria; Coltro, Giacomo; Loscocco, Giuseppe Gaetano; Rotunno, Giada; Angori, Eva; Borri, Filippo C; Tefferi, Ayalew; Vannucchi, Alessandro M (2023). Phenotypic correlations of CALR mutation variant allele frequency in patients with myelofibrosis. BLOOD CANCER JOURNAL, vol. 13, pp. 21-21, ISSN:2044-5385
DOI
Mascarenhas, John; Gleitz, Hélène F E; Chifotides, Helen T; Harrison, Claire N; Verstovsek, Srdan; Vannucchi, Alessandro Maria; Rampal, Raajit K; Kiladjian, Jean-Jacques; Vainchenker, William; Hoffman, Ronald; Schneider, Rebekka K; List, Alan F (2023). Biological drivers of clinical phenotype in myelofibrosis. LEUKEMIA, vol. 37, pp. 255-264, ISSN:1476-5551
DOI
Mascarenhas, John; Kremyanskaya, Marina; Patriarca, Andrea; Palandri, Francesca; Devos, Timothy; Passamonti, Francesco; Rampal, Raajit K; Mead, Adam J; Hobbs, Gabriella; Scandura, Joseph M; Talpaz, Moshe; Granacher, Nikki; Somervaille, Tim C P; Hoffman, Ronald; Wondergem, Marielle J; Salama, Mohamed E; Colak, Gozde; Cui, Jike; Kiladjian, Jean-Jacques; Vannucchi, Alessandro M; Verstovsek, Srdan; Curto-García, Natalia; Harrison, Claire; Gupta, Vikas (2023). MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis. JOURNAL OF CLINICAL ONCOLOGY, pp. 1-13, ISSN:1527-7755
DOI
Sordi, Benedetta; Vanderwert, Fiorenza; Crupi, Francesca; Gesullo, Francesca; Zanotti, Roberta; Bonadonna, Patrizia; Crosera, Lara; Elena, Chiara; Fiorelli, Nicolas; Ferrari, Jacqueline; Grifoni, Federica; Sciumè, Mariarita; Parente, Roberta; Triggiani, Massimo; Palterer, Boaz; Mecheri, Valentina; Almerigogna, Fabio; Santi, Raffaella; Di Medio, Lisa; Brandi, Maria Luisa; Iorno, Maria Loredana; Ciardetti, Isabella; Bencini, Sara; Annunziato, Francesco; Mannarelli, Carmela; Pieri, Lisa; Guglielmelli, Paola; Mannelli, Francesco; Vannucchi, Alessandro M (2023). Disease correlates and clinical relevance of hereditary α-tryptasemia in patients with systemic mastocytosis. THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 151, pp. 485-493, ISSN:1097-6825
DOI
Tefferi, Ayalew; Vannucchi, Alessandro M (2023). JAK2 inhibitor treatment of anemia in myelofibrosis. AMERICAN JOURNAL OF HEMATOLOGY, pp. 1-3, ISSN:1096-8652
DOI
Verstovsek, Srdan; Gerds, Aaron T; Vannucchi, Alessandro M; Al-Ali, Haifa Kathrin; Lavie, David; Kuykendall, Andrew T; Grosicki, Sebastian; Iurlo, Alessandra; Goh, Yeow Tee; Lazaroiu, Mihaela C; Egyed, Miklos; Fox, Maria Laura; McLornan, Donal; Perkins, Andrew; Yoon, Sung-Soo; Gupta, Vikas; Kiladjian, Jean-Jacques; Granacher, Nikki; Lee, Sung-Eun; Ocroteala, Luminita; Passamonti, Francesco; Harrison, Claire N; Klencke, Barbara J; Ro, Sunhee; Donahue, Rafe; Kawashima, Jun; Mesa, Ruben (2023). Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study. THE LANCET, vol. 401, pp. 269-280, ISSN:1474-547X
DOI
Verstovsek, Srdan; Kiladjian, Jean-Jacques; Vannucchi, Alessandro M; Mesa, Ruben A; Squier, Peg; Hamer-Maansson, J E; Harrison, Claire (2023). Early intervention in myelofibrosis and impact on outcomes: A pooled analysis of the COMFORT-I and COMFORT-II studies. CANCER, pp. 1-10, ISSN:1097-0142
DOI
Verstovsek, Srdan; Mesa, Ruben A; Gupta, Vikas; Lavie, David; Dubruille, Viviane; Cambier, Nathalie; Platzbecker, Uwe; Hus, Marek; Xicoy, Blanca; Oh, Stephen T; Kiladjian, Jean-Jacques; Vannucchi, Alessandro M; Gerds, Aaron T; Egyed, Miklos; Mayer, Jiri; Sacha, Tomasz; Kawashima, Jun; Morris, Marc; Huang, Mei; Harrison, Claire N (2023). Momelotinib Long-Term Safety and Survival in Myelofibrosis: Integrated Analysis of Phase 3 Randomized-Controlled Trials. BLOOD ADVANCES, pp. 1-31, ISSN:2473-9537
DOI
Bianchi, Elisa; Rontauroli, Sebastiano; Tavernari, Lara; Mirabile, Margherita; Pedrazzi, Francesca; Genovese, Elena; Sartini, Stefano; Dall'Ora, Massimiliano; Grisendi, Giulia; Fabbiani, Luca; Maccaferri, Monica; Carretta, Chiara; Parenti, Sandra; Fantini, Sebastian; Bartalucci, Niccolò; Calabresi, Laura; Balliu, Manjola; Guglielmelli, Paola; Potenza, Leonardo; Tagliafico, Enrico; Losi, Lorena; Dominici, Massimo; Luppi, Mario; Vannucchi, Alessandro Maria; Manfredini, Rossella (2023). Inhibition of ERK1/2 signaling prevents bone marrow fibrosis by reducing osteopontin plasma levels in a myelofibrosis mouse model. LEUKEMIA, pp. 1-12, ISSN:0887-6924
DOI
Accesso ONLINE all'editore
Arciprete, Francesca; Verachi, Paola; Martelli, Fabrizio; Valeri, Mauro; Balliu, Manjola; Guglielmelli, Paola; Vannucchi, Alessandro Maria; Migliaccio, Anna Rita; Zingariello, Maria (2023). Inhibition of CXCR1/2 reduces the emperipolesis between neutrophils and megakaryocytes in the Gata1low model of myelofibrosis. EXPERIMENTAL HEMATOLOGY, vol. 121, pp. 30-37, ISSN:0301-472X
DOI
Mannelli, Francesco; Crupi, Francesca; Zanotti, Roberta; Pagano, Livio; Rapezzi, Davide; Tanasi, Ilaria; Criscuolo, Marianna; Bonifacio, Massimiliano; Fresa, Alberto; Guglielmelli, Paola; Vannucchi, Alessandro M (2023). The clinical experience of compassionate use program for avapritinib: implications for drug positioning in the therapeutic scenario of systemic mastocytosis. THERAPEUTIC ADVANCES IN HEMATOLOGY, vol. 14, pp. 1-14, ISSN:2040-6207
DOI
Atanasio, A; Vanni, A; Maggi, L; Pilerci, S; Mazzoni, A; Capone, M; Crupi, F; Cicogna, P; Boldrini, V; Tekle, S; Colao, M G; Borella, M; Paoli, C; Rossolini, G M; Vannucchi, A M; Annunziato, F; Guglielmelli, P (2023). Humoral and cellular responses after third dose of SARS-CoV-2 vaccine in myeloproliferative neoplasms patients on ruxolitinib therapy. LEUKEMIA RESEARCH, vol. 131, pp. 107330-107330, ISSN:0145-2126
DOI
Marangoni, Davide; Antonello, Roberta Maria; Coppi, Marco; Palazzo, Marianna; Nassi, Luca; Streva, Noemi; Povolo, Laura; Malentacchi, Francesca; Zammarchi, Lorenzo; Rossolini, Gian Maria; Vannucchi, Alessandro Maria; Bartoloni, Alessandro; Spinicci, Michele (2023). Combination regimen of nirmatrelvir/ritonavir and molnupiravir for the treatment of persistent SARS-CoV-2 infection: A case report and a scoping review of the literature. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, vol. 133, pp. 53-56, ISSN:1878-3511
DOI
Calabresi, Laura; Carretta, Chiara; Romagnoli, Simone; Rotunno, Giada; Parenti, Sandra; Bertesi, Matteo; Bartalucci, Niccolò; Rontauroli, Sebastiano; Chiereghin, Chiara; Castellano, Sara; Gentili, Giulia; Maccari, Chiara; Vanderwert, Fiorenza; Mannelli, Francesco; Della Porta, Matteo; Manfredini, Rossella; Vannucchi, Alessandro Maria; Guglielmelli, Paola (2023). Clonal dynamics and copy number variants by single-cell analysis in leukemic evolution of myeloproliferative neoplasms. AMERICAN JOURNAL OF HEMATOLOGY, vol. 98, pp. 1520-1531, ISSN:0361-8609
DOI
Gupta, Vikas; Mascarenhas, John; Kremyanskaya, Marina; Rampal, Raajit K; Talpaz, Moshe; Kiladjian, Jean-Jacques; Vannucchi, Alessandro M; Verstovsek, Srdan; Colak, Gozde; Dey, Debarshi; Harrison, Claire (2023). Matching-adjusted indirect comparison of the pelabresib-ruxolitinib combination vs JAKi monotherapy in myelofibrosis. BLOOD ADVANCES, vol. 7, pp. 5421-5432, ISSN:2473-9537
DOI
g loscocco; am vannucchi (2023). Myeloid sarcoma: more and less than a distinct entity. ANNALS OF HEMATOLOGY, pp. 1-12, ISSN:0939-5555
DOI
Mannelli, Francesco; Guglielmelli, Paola; Fazi, Paola; Crea, Enrico; Piciocchi, Alfonso; Vignetti, Marco; Amadori, Sergio; Pane, Fabrizio; Venditti, Adriano; Vannucchi, Alessandro M (2023). ENABLE: treatment combination including decitabine and venetoclax in acute myeloid leukemia secondary to myeloproliferative neoplasms. FUTURE ONCOLOGY, vol. 19, pp. 103-111, ISSN:1744-8301
DOI
Mannelli, Francesco; Gesullo, Francesca; Mannarelli, Carmela; Vanderwert, Fiorenza; Lazzi, Stefano; Mungai, Francesco; Berti, Valentina; Santi, Raffaella; Guglielmelli, Paola; Vannucchi, Alessandro M (2023). Diagnostic and therapeutic challenges in mast cell sarcoma. AMERICAN JOURNAL OF HEMATOLOGY, vol. 98, pp. 529-532, ISSN:0361-8609
DOI
Coltro, Giacomo; Sant'Antonio, Emanuela; Palumbo, Giuseppe A; Mannelli, Francesco; De Stefano, Valerio; Ruggeri, Marco; Elli, Elena M; Zanotti, Roberta; Borsani, Oscar; Bertozzi, Irene; Duminuco, Andrea; Betti, Silvia; Carli, Giuseppe; Cavalca, Fabrizio; Tanasi, Ilaria; Rumi, Elisa; Randi, Maria L; Garibaldi, Bruno; Loscocco, Giuseppe G; Guglielmelli, Paola; Vannucchi, Alessandro M (2023). Assessment of the efficacy and tolerability of ruxolitinib for the treatment of myelofibrosis patients in a real-life setting: An Italian MYNERVA Project. CANCER MEDICINE, vol. 12, pp. 8166-8171, ISSN:2045-7634
DOI
Polverelli, Nicola; Hernández-Boluda, Juan Carlos; Czerw, Tomasz; Barbui, Tiziano; D'Adda, Mariella; Deeg, Hans Joachim; Ditschkowski, Markus; Harrison, Claire; Kröger, Nicolaus Martin; Mesa, Ruben; Passamonti, Francesco; Palandri, Francesca; Pemmaraju, Naveen; Popat, Uday; Rondelli, Damiano; Vannucchi, Alessandro Maria; Verstovsek, Srdan; Robin, Marie; Colecchia, Antonio; Grazioli, Luigi; Damiani, Enrico; Russo, Domenico; Brady, Jessica; Patch, David; Blamek, Slawomir; Damaj, Gandhi Laurent; Hayden, Patrick; McLornan, Donal P; Yakoub-Agha, Ibrahim (2023). Splenomegaly in patients with primary or secondary myelofibrosis who are candidates for allogeneic hematopoietic cell transplantation: a Position Paper on behalf of the Chronic Malignancies Working Party of the EBMT. THE LANCET. HAEMATOLOGY, vol. 10, pp. 59-70, ISSN:2352-3026
DOI
Abenavoli, Elisabetta Maria; Barbetti, Matteo; Linguanti, Flavia; Mungai, Francesco; Nassi, Luca; Puccini, Benedetta; Romano, Ilaria; Sordi, Benedetta; Santi, Raffaella; Passeri, Alessandro; Sciagrà, Roberto; Talamonti, Cinzia; Cistaro, Angelina; Vannucchi, Alessandro Maria; Berti, Valentina (2023). Characterization of Mediastinal Bulky Lymphomas with FDG-PET-Based Radiomics and Machine Learning Techniques. CANCERS, vol. 15, pp. 0-0, ISSN:2072-6694
DOI
Gangat, Naseema; Singh, Amritpal; Szuber, Natasha; Begna, Kebede; Elliott, Michelle; Wolanskyj-Spinner, Alexandra; Hanson, Curtis A; Pardanani, Animesh; De Stefano, Valerio; Barbui, Tiziano; Vannucchi, Alessandro M; Tefferi, Ayalew (2022). Site-specific venous thrombosis in essential thrombocythemia: Impact on subsequent vascular events and survival. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, vol. 20, pp. 2439-2443, ISSN:1538-7933
DOI
Francesca Gorini , Michele Santoro , Anna Pierini , Lorena Mezzasalma , Silvia Baldacci , Elena Bargagli , Alessandra Boncristiano , Maurizia Rossana Brunetto , Paolo Cameli , Francesco Cappelli , Giancarlo Castaman , Barbara Coco , Maria Alice Donati , Renzo Guerrini , Silvia Linari , Vittoria Murro , Iacopo Olivotto , Paola Parronchi , Francesca Pochiero , Oliviero Rossi , Barbara Scappini , Andrea Sodi , Alessandro Maria Vannucchi , Alessio Coi (2022). Orphan Drug Use in Patients With Rare Diseases: A Population-Based Cohort Study. FRONTIERS IN PHARMACOLOGY, vol. 13, pp. 0-0, ISSN:1663-9812
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Kuykendall, Andrew T; Sun, Libo; Mascarenhas, John; Kiladjian, Jean-Jacques; Vannucchi, Alessandro M; Wang, Julia; Xia, Qi; Zhu, Eugene; Feller, Faye; Rizo, Aleksandra; Bussolari, Jacqueline; Wan, Ying; Komrokji, Rami (2022). Favorable overall survival with imetelstat in relapsed/refractory myelofibrosis patients compared with real-world data. ANNALS OF HEMATOLOGY, vol. 101, pp. 139-146, ISSN:0939-5555
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Mascarenhas, John; Harrison, Claire N; Kiladjian, Jean-Jacques; Komrokji, Rami S; Koschmieder, Steffen; Vannucchi, Alessandro M; Berry, Tymara; Redding, Denise; Sherman, Laurie; Dougherty, Souria; Peng, Lixian; Sun, Libo; Huang, Fei; Wan, Ying; Feller, Faye M; Rizo, Aleksandra; Verstovsek, Srdan (2022). Imetelstat in intermediate-2 or high-risk myelofibrosis refractory to JAK inhibitor: IMpactMF phase III study design. FUTURE ONCOLOGY, vol. 18, pp. 2393-2402, ISSN:1744-8301
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Harrison, Claire; Heidel, Florian H; Vannucchi, Alessandro M; Kiladjian, Jean-Jacques; Hayat, Amjad; Passamonti, Francesco; Conneally, Eibhlin; Kindler, Thomas; Martino, Bruno; Lipka, Daniel B; Stefanelli, Tommaso; Roussou, Pantelia; Germano, Davide; Ewan, Jacqueline; Ribrag, Vincent (2022). A Phase Ib Dose-finding Study of Panobinostat and Ruxolitinib in Myelofibrosis. HEMASPHERE, vol. 6, pp. 1-4, ISSN:2572-9241
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Mascarenhas, John; Kosiorek, Heidi E; Prchal, Josef T; Rambaldi, Alessandro; Berenzon, Dmitriy; Yacoub, Abdulraheem; Harrison, Claire N; McMullin, Mary Frances; Vannucchi, Alessandro M; Ewing, Joanne; O'Connell, Casey L; Kiladjian, Jean-Jacques; Mead, Adam J; Winton, Elliott F; Leibowitz, David S; De Stefano, Valerio; Arcasoy, Murat O; Kessler, Craig M; Catchatourian, Rosalind; Rondelli, Damiano; Silver, Richard T; Bacigalupo, Andrea; Nagler, Arnon; Kremyanskaya, Marina; Levine, Max F; Arango Ossa, Juan E; McGovern, Erin; Sandy, Lonette; Salama, Mohamad E; Najfeld, Vesna; Tripodi, Joseph; Farnoud, Noushin; Penson, Alexander V; Weinberg, Rona Singer; Price, Leah; Goldberg, Judith D; Barbui, Tiziano; Marchioli, Roberto; Tognoni, Gianni; Rampal, Raajit K; Mesa, Ruben A; Dueck, Amylou C; Hoffman, Ronald (2022). A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia. BLOOD, vol. 139, pp. 2931-2941, ISSN:0006-4971
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Passamonti, Francesco; Romano, Alessandra; Salvini, Marco; Merli, Francesco; Porta, Matteo G Della; Bruna, Riccardo; Coviello, Elisa; Romano, Ilaria; Cairoli, Roberto; Lemoli, Roberto; Farina, Francesca; Venditti, Adriano; Busca, Alessandro; Ladetto, Marco; Massaia, Massimo; Pinto, Antonio; Arcaini, Luca; Tafuri, Agostino; Marchesi, Francesco; Fracchiolla, Nicola; Bocchia, Monica; Armiento, Daniele; Candoni, Anna; Krampera, Mauro; Luppi, Mario; Cardinali, Valeria; Galimberti, Sara; Cattaneo, Chiara; La Barbera, Elettra Ortu; Mina, Roberto; Lanza, Francesco; Visani, Giuseppe; Musto, Pellegrino; Petrucci, Luigi; Zaja, Francesco; Grossi, Paolo A; Bertù, Lorenza; Pagano, Livio; Corradini, Paolo; ITA-HEMA-COV Investigators*: Enrico Derenzini, Monia Marchetti, Anna M Scattolin, Alessandro Corso, Patrizia Tosi, Filippo Gherlinzoni, Carlo Gambacorti Passerini, Michele Cavo, Carmen Fava, Mauro Turrini, Carlo Visco, Patrizia Zappasodi, Michele Merli, Barbara Mora, Alessandro M Vannucchi (2021). COVID-19 elicits an impaired antibody response against SARS-CoV-2 in patients with haematological malignancies. BRITISH JOURNAL OF HAEMATOLOGY, vol. 195, pp. 371-377, ISSN:1365-2141
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Fantini S.; Rontauroli S.; Sartini S.; Mirabile M.; Bianchi E.; Badii F.; Maccaferri M.; Guglielmelli P.; Ottone T.; Palmieri R.; Genovese E.; Carretta C.; Parenti S.; Mallia S.; Tavernari L.; Salvadori C.; Gesullo F.; Maccari C.; Zizza M.; Grande A.; Salmoiraghi S.; Mora B.; Potenza L.; Rosti V.; Passamonti F.; Rambaldi A.; Voso M.T.; Mecucci C.; Tagliafico E.; Luppi M.; Vannucchi A.M.; Manfredini R. (2021). Increased plasma levels of lncrnas linc01268, gas5 and malat1 correlate with negative prognostic factors in myelofibrosis. CANCERS, vol. 13, pp. 4744-4765, ISSN:2072-6694
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Galata G.; Garcia-Montero A.C.; Kristensen T.; Dawoud A.A.Z.; Munoz-Gonzalez J.I.; Meggendorfer M.; Guglielmelli P.; Hoade Y.; Alvarez-Twose I.; Gieger C.; Strauch K.; Ferrucci L.; Tanaka T.; Bandinelli S.; Schnurr T.M.; Haferlach T.; Broesby-Olsen S.; Vestergaard H.; Moller M.B.; Bindslev-Jensen C.; Vannucchi A.M.; Orfao A.; Radia D.; Reiter A.; Chase A.J.; Cross N.C.P.; Tapper W.J. (2021). Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis. AMERICAN JOURNAL OF HUMAN GENETICS, vol. 108, pp. 284-294, ISSN:0002-9297
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Tanasi, Ilaria; Bonifacio, Massimiliano; Pizzolato, Miriam; Irene Grifoni, Federica; Sciumè, Mariarita; Elena, Chiara; Benvenuti, Pietro; Mannelli, Francesco; Parente, Roberta; Schena, Donatella; Scaffidi, Luigi; Bonadonna, Patrizia; Papayannidis, Cristina; Rondoni, Michela; Criscuolo, Marianna; Vannucchi, Alessandro M.; Triggiani, Massimo; Martinelli, Giovanni; Krampera, Mauro; Zanotti, Roberta (2021). Familial occurrence of systemic and cutaneous mastocytosis in an adult multicentre series. BRITISH JOURNAL OF HAEMATOLOGY, vol. 193, pp. 845-848, ISSN:0007-1048
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Todisco G.; Creignou M.; Galli A.; Guglielmelli P.; Rumi E.; Roncador M.; Rizzo E.; Nannya Y.; Pietra D.; Elena C.; Bono E.; Molteni E.; Rosti V.; Catricala S.; Sarchi M.; Dimitriou M.; Ungerstedt J.; Vannucchi A.M.; Hellstrom-Lindberg E.; Ogawa S.; Cazzola M.; Malcovati L. (2021). Co-mutation pattern, clonal hierarchy, and clone size concur to determine disease phenotype of SRSF2 P95-mutated neoplasms. LEUKEMIA, vol. 35, pp. 2371-2381, ISSN:0887-6924
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Verstovsek, Srdan; Mesa, Ruben; Talpaz, Moshe; Kiladjian, Jean-Jacques; Harrison, Claire N; Oh, Stephen T; Vannucchi, Alessandro M; Rampal, Raajit; Scott, Bart L; Buckley, Sarah A; Craig, Adam R; Roman-Torres, Karisse; Mascarenhas, John O (2021). Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia. HAEMATOLOGICA, pp. 1-21, ISSN:1592-8721
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Gotlib J.; Reiter A.; Radia D.H.; Deininger M.W.; George T.I.; Panse J.; Vannucchi A.M.; Platzbecker U.; Alvarez-Twose I.; Mital A.; Hermine O.; Dybedal I.; Hexner E.O.; Hicks L.K.; Span L.; Mesa R.; Bose P.; Pettit K.M.; Heaney M.L.; Oh S.T.; Sen J.; Lin H.-M.; Mar B.G.; DeAngelo D.J. (2021). Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial. NATURE MEDICINE, vol. 27, pp. 2192-2199, ISSN:1078-8956
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Vannucchi A.M.; Mortara A.; D'alessio A.; Morelli M.; Tedeschi A.; Festuccia M.B.; Monforte A.D.; Capochiani E.; Selleri C.; Simonetti F.; Saracino A.; Rapezzi D.; Badagliacca M.R.; Falasca K.; Molteni A.; Palazzolo R.; Schettino G.; Bocchia M.; Turrini M.; Ascierto P.A.; Zuurman M.; Paley C.; Coco P.; Saglio G. (2021). Jak inhibition with ruxolitinib in patients with covid‐19 and severe pneumonia: Multicenter clinical experience from a compassionate use program in italy. JOURNAL OF CLINICAL MEDICINE, vol. 10, pp. 3752-3764, ISSN:2077-0383
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Loscocco G.G.; Coltro G.; Guglielmelli P.; Vannucchi A.M. (2021). Integration of molecular information in risk assessment of patients with myeloproliferative neoplasms. CELLS, vol. 10, pp. 1962-1984, ISSN:2073-4409
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Gangat N.; Guglielmelli P.; Betti S.; Farrukh F.; Carobbio A.; Barbui T.; Vannucchi A.M.; De Stefano V.; Tefferi A. (2021). Cerebral venous thrombosis and myeloproliferative neoplasms: A three-center study of 74 consecutive cases. AMERICAN JOURNAL OF HEMATOLOGY, vol. 96, pp. 1580-1586, ISSN:0361-8609
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Bartalucci N.; Romagnoli S.; Vannucchi A.M. (2021). A blood drop through the pore: nanopore sequencing in hematology. TRENDS IN GENETICS, pp. 1-15, ISSN:0168-9525
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Vanderwert, Fiorenza Irushani; Sordi, Benedetta; Mannelli, Francesco; Palterer, Boaz; Gesullo, Francesca; Mecheri, Valentina; Santi, Raffaella; Mannarelli, Carmela; Crupi, Francesca; Zanotti, Roberta; Grifoni, Federica Irene; Elena, Chiara; Parente, Roberta; Triggiani, Massimo; Lisa, Pieri; Almerigogna, Fabio; Guglielmelli, Paola; Vannucchi, Alessandro (2021). Screening for Hereditary Alpha-Tryptasemia in Subjects with Systemic Mastocytosis (SM) and Non-SM Mast Cell Activation Symptoms. BLOOD, vol. 138, pp. 1500-1502, ISSN:0006-4971
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Guglielmelli, Paola; Mazzoni, Alessio; Maggi, Laura; Kiros, Seble Tekle; Zammarchi, Lorenzo; Pilerci, Sofia; Rocca, Arianna; Spinicci, Michele; Borella, Miriam; Bartoloni, Alessandro; Rossolini, Gian Maria; Annunziato, Francesco; Vannucchi, Alessandro M (2021). Impaired response to first SARS-CoV-2 dose vaccination in myeloproliferative neoplasm patients receiving ruxolitinib. AMERICAN JOURNAL OF HEMATOLOGY, pp. 1-1, ISSN:0361-8609
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Mannelli, Francesco; Gianfaldoni, Giacomo; Guglielmelli, Paola; Buccisano, Francesco; Caporale, Roberto; Chiarini, Marco; Rossi, Giuseppe; Venditti, Adriano; Fazi, Paola; Crea, Enrico; Piciocchi, Alfonso; Voso, Maria Teresa; Vignetti, Marco; Amadori, Sergio; Vannucchi, Alessandro Maria (2021). AMELIORATE: early intensification in FLT3-mutated acute myeloid leukemia based on peripheral blast clearance – MYNERVA-GIMEMA AML1919 trial. FUTURE ONCOLOGY, vol. 17, pp. 3787-3796, ISSN:1479-6694
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Tefferi A.; Szuber N.; Pardanani A.; Hanson C.A.; Vannucchi A.M.; Barbui T.; Gangat N. (2021). Extreme thrombocytosis in low-risk essential thrombocythemia: Retrospective review of vascular events and treatment strategies. AMERICAN JOURNAL OF HEMATOLOGY, vol. 96, pp. E182-E184, ISSN:0361-8609
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Zanelli, Magda; Loscocco, Giuseppe G.; Sabattini, Elena; Zizzo, Maurizio; Sanguedolce, Francesca; Panico, Luigi; Fanni, Daniela; Santi, Raffaella; Caprera, Cecilia; Rossi, Cristiana; Soriano, Alessandra; Cavazza, Alberto; Giunta, Alessandro; Mecucci, Cristina; Vannucchi, Alessandro M.; Pileri, Stefano A.; Ascani, Stefano (2021). T-Cell Lymphoblastic Lymphoma Arising in the Setting of Myeloid/Lymphoid Neoplasms with Eosinophilia: LMO2 Immunohistochemistry as a Potentially Useful Diagnostic Marker. CANCERS, vol. 13, pp. 1-17, ISSN:2072-6694
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Tefferi A.; Vannucchi A.M.; Barbui T. (2021). Polycythemia vera: historical oversights, diagnostic details, and therapeutic views. LEUKEMIA, vol. 35, pp. 3339-3351, ISSN:0887-6924
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Guglielmelli P.; Gangat N.; Coltro G.; Lasho T.L.; Loscocco G.G.; Finke C.M.; Morsia E.; Sordi B.; Szuber N.; Hanson C.A.; Pardanani A.; Vannucchi A.M.; Tefferi A. (2021). Mutations and thrombosis in essential thrombocythemia. BLOOD CANCER JOURNAL, vol. 11, pp. 77-80, ISSN:2044-5385
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Gangat N.; Guglielmelli P.; Szuber N.; Begna K.H.; Patnaik M.M.; Litzow M.R.; Al-Kali A.; Foran J.M.; Palmer J.M.; Alkhateeb H.; Elliott M.A.; Hanson C.A.; Pardanani A.; Mannelli F.; Vannucchi A.M.; Tefferi A. (2021). Venetoclax with azacitidine or decitabine in blast-phase myeloproliferative neoplasm: A multicenter series of 32 consecutive cases. AMERICAN JOURNAL OF HEMATOLOGY, vol. 96, pp. 781-789, ISSN:0361-8609
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Mascarenhas J.; Komrokji R.S.; Palandri F.; Martino B.; Niederwieser D.; Reiter A.; Scott B.L.; Baer M.R.; Hoffman R.; Odenike O.; Vannucchi A.M.; Bussolari J.; Zhu E.; Rose E.; Sherman L.; Dougherty S.; Sun L.; Huang F.; Wan Y.; Feller F.M.; Rizo A.; Kiladjian J.-J. (2021). Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis. JOURNAL OF CLINICAL ONCOLOGY, vol. 39, pp. 2881-2892, ISSN:1527-7755
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Rambaldi A.; Iurlo A.; Vannucchi A.M.; Martino B.; Guarini A.; Ruggeri M.; von Bubnoff N.; De Muro M.; McMullin M.F.; Luciani S.; Martinelli V.; Nogai A.; Rosti V.; Ricco A.; Bettica P.; Manzoni S.; Di Tollo S. (2021). Long-term safety and efficacy of givinostat in polycythemia vera: 4-year mean follow up of three phase 1/2 studies and a compassionate use program. BLOOD CANCER JOURNAL, vol. 11, pp. 53-59, ISSN:2044-5385
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Rontauroli S.; Castellano S.; Guglielmelli P.; Zini R.; Bianchi E.; Genovese E.; Carretta C.; Parenti S.; Fantini S.; Mallia S.; Tavernari L.; Sartini S.; Mirabile M.; Mannarelli C.; Gesullo F.; Pacilli A.; Pietra D.; Rumi E.; Salmoiraghi S.; Mora B.; Villani L.; Grilli A.; Rosti V.; Barosi G.; Passamonti F.; Rambaldi A.; Malcovati L.; Cazzola M.; Bicciato S.; Tagliafico E.; Vannucchi A.M.; Manfredini R. (2021). Gene expression profile correlates with molecular and clinical features in patients with myelofibrosis. BLOOD ADVANCES, vol. 5, pp. 1452-1462, ISSN:2473-9529
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Loscocco G.G.; Guglielmelli P.; Gangat N.; Rossi E.; Mannarelli C.; Betti S.; Maccari C.; Ramundo F.; Jadoon Y.; Gesullo F.; Ceglie S.; Paoli C.; Pardanani A.; De Stefano V.; Tefferi A.; Vannucchi A.M. (2021). Clinical and molecular predictors of fibrotic progression in essential thrombocythemia: A multicenter study involving 1607 patients. AMERICAN JOURNAL OF HEMATOLOGY, vol. 96, pp. 1472-1480, ISSN:0361-8609
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Verstovsek S.; Chen C.-C.; Egyed M.; Ellis M.; Fox L.; Goh Y.T.; Gupta V.; Harrison C.; Kiladjian J.-J.; Lazaroiu M.C.; Mead A.; McLornan D.; McMullin M.F.; Oh S.T.; Perkins A.; Platzbecker U.; Scheid C.; Vannucchi A.; Yoon S.-S.; Kowalski M.M.; Mesa R.A. (2021). MOMENTUM: Momelotinib vs danazol in patients with myelofibrosis previously treated with JAKi who are symptomatic and anemic. FUTURE ONCOLOGY, vol. 17, pp. 1449-1458, ISSN:1479-6694
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Loscocco G.G.; Rotunno G.; Mannelli L.; Mannelli F.; Vergoni F.; Guglielmelli P.; Vannucchi A.M. (2021). BRAFV600E mutation in the wrong place: a case of concomitant polycythemia vera, hairy cell leukemia, and thyroid adenoma. TUMORI, vol. 107, pp. NP28-NP32, ISSN:0300-8916
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Mesa R.A.; Schaap N.; Vannucchi A.M.; Kiladjian J.-J.; Passamonti F.; Zweegman S.; Talpaz M.; Verstovsek S.; Rose S.; Abraham P.; Lord-Bessen J.; Tang D.; Guo S.; Ye X.; Harrison C.N. (2021). Patient-reported Effects of Fedratinib, an Oral, Selective Inhibitor of Janus Kinase 2, on Myelofibrosis-related Symptoms and Health-related Quality of Life in the Randomized, Placebo-controlled, Phase III JAKARTA Trial. HEMASPHERE, vol. 5, pp. 1-10, ISSN:2572-9241
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Barbui T.; Vannucchi A.M.; De Stefano V.; Masciulli A.; Carobbio A.; Ferrari A.; Ghirardi A.; Rossi E.; Ciceri F.; Bonifacio M.; Iurlo A.; Palandri F.; Benevolo G.; Pane F.; Ricco A.; Carli G.; Caramella M.; Rapezzi D.; Musolino C.; Siragusa S.; Rumi E.; Patriarca A.; Cascavilla N.; Mora B.; Cacciola E.; Mannarelli C.; Loscocco G.G.; Guglielmelli P.; Betti S.; Lunghi F.; Scaffidi L.; Bucelli C.; Vianelli N.; Bellini M.; Finazzi M.C.; Tognoni G.; Rambaldi A. (2021). Ropeginterferon alfa-2b versus phlebotomy in low-risk patients with polycythaemia vera (Low-PV study): a multicentre, randomised phase 2 trial. THE LANCET. HAEMATOLOGY, vol. 8, pp. e175-e184, ISSN:2352-3026
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Barbui T.; Iurlo A.; Masciulli A.; Carobbio A.; Ghirardi A.; Rossi G.; Harrison C.; Alvarez-Larran A.; Elli E.M.; Kiladjian J.-J.; Gasior Kabat M.; Marin Sanchez A.; Palandri F.; Andrade-Campos M.M.; Vannucchi A.M.; Carreno-Tarragona G.; Papadopoulos P.; Quiroz Cervantes K.; Angeles Foncillas M.; Fox M.L.; Sagues Serrano M.; Rumi E.; Osorio S.; Benevolo G.; Patriarca A.; Navas Elorza B.; Garcia-Gutierrez V.; Magro Mazo E.; Lunghi F.; Bonifacio M.; De Stefano V.; Hernandez-Boluda J.C.; Lopez Abadia E.; Angona A.; Xicoy Cirici B.; Ruggeri M.; Koschmieder S.; Sobas M.A.; Cuevas B.; Cattaneo D.; Daffini R.; Bellini M.; Curto-Garcia N.; Garrote M.; Cavalca F.; Benajiba L.; Bellosillo B.; Guglielmelli P.; Borsani O.; Betti S.; Salmoiraghi S.; Rambaldi A. (2021). Long-term follow-up of recovered MPN patients with COVID-19. BLOOD CANCER JOURNAL, vol. 11, pp. 1-4, ISSN:2044-5385
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Barbui T.; De Stefano V.; Carobbio A.; Iurlo A.; Alvarez-Larran A.; Cuevas B.; Ferrer Marin F.; Vannucchi A.M.; Palandri F.; Harrison C.; Sibai H.; Griesshammer M.; Bonifacio M.; Elli E.M.; Trotti C.; Koschmieder S.; Carli G.; Benevolo G.; Ianotto J.-C.; Goel S.; Falanga A.; Betti S.; Cattaneo D.; Arellano-Rodrigo E.; Mannelli L.; Vianelli N.; Doyle A.; Gupta V.; Wille K.; Tremblay D.; Mascarenhas J. (2021). Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients. LEUKEMIA, vol. 35, pp. 2989-2993, ISSN:0887-6924
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Zampieri, Mattia; Allinovi, Marco; Olivotto, Iacopo; Antonioli, Elisabetta; Gabriele, Martina; Argirò, Alessia; Fumagalli, Carlo; Nardi, Giulia; Di Mario, Carlo; Vannucchi, Alessandro M; Perfetto, Federico; Cappelli, Francesco (2021). Ventricular tachyarrhythmias and sudden cardiac death in light-chain amyloidosis: a clash of cardio-toxicities?. BRITISH JOURNAL OF HAEMATOLOGY, vol. 193, pp. e27-e31, ISSN:0007-1048
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Vannucchi A.M.; Sordi B.; Morettini A.; Nozzoli C.; Poggesi L.; Pieralli F.; Bartoloni A.; Atanasio A.; Miselli F.; Paoli C.; Loscocco G.G.; Fanelli A.; Para O.; Berni A.; Tassinari I.; Zammarchi L.; Maggi L.; Mazzoni A.; Scotti V.; Falchetti G.; Malandrino D.; Luise F.; Millotti G.; Bencini S.; Capone M.; Piccinni M.P.; Annunziato F.; Guglielmelli P.; Mannelli F.; Coltro G.; Fantoni D.; Borella M.; Ravenda E.; Peruzzi B.; Caporale R.; Cosmi L.; Liotta F.; Lombardelli L.; Logiodice F.; Vanni A.; Salvati L.; Lazzeri C.; Bonizzoli M.; Peris A.; Cianchi G.; Bosi A.; Pucatti M.; Fontanari P.; Benemei S.; MatucciCerinic M.; Turco L. (2021). Compassionate use of JAK1/2 inhibitor ruxolitinib for severe COVID-19: a prospective observational study. LEUKEMIA, pp. 1121-1133, ISSN:0887-6924
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Guglielmelli P.; Loscocco G.G.; Mannarelli C.; Rossi E.; Mannelli F.; Ramundo F.; Coltro G.; Betti S.; Maccari C.; Ceglie S.; Chiusolo P.; Paoli C.; Barbui T.; Tefferi A.; De Stefano V.; Vannucchi A.M. (2021). JAK2V617F variant allele frequency >50% identifies patients with polycythemia vera at high risk for venous thrombosis. BLOOD CANCER JOURNAL, vol. 11, pp. 199-208, ISSN:2044-5385
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Romagnoli S.; Bartalucci N.; Gesullo F.; Balliu M.; Bonifacio S.; Fernandez A.G.L.; Mannelli F.; Bolognini D.; Pelo E.; Mecucci C.; Guglielmelli P.; Vannucchi A.M. (2021). Nanopore sequencing for the screening of myeloid and lymphoid neoplasms with eosinophilia and rearrangement of PDGFRα, PDGFRβ, FGFR1 or PCM1-JAK2. BIOMARKER RESEARCH, vol. 9, pp. 83-86, ISSN:2050-7771
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Barbui T.; De Stefano V.; Alvarez-Larran A.; Iurlo A.; Masciulli A.; Carobbio A.; Ghirardi A.; Ferrari A.; Cancelli V.; Elli E.M.; Andrade-Campos M.M.; Kabat M.G.; Kiladjian J.-J.; Palandri F.; Benevolo G.; Garcia-Gutierrez V.; Fox M.L.; Foncillas M.A.; Morcillo C.M.; Rumi E.; Osorio S.; Papadopoulos P.; Bonifacio M.; Cervantes K.S.Q.; Serrano M.S.; Carreno-Tarragona G.; Sobas M.A.; Lunghi F.; Patriarca A.; Elorza B.N.; Angona A.; Mazo E.M.; Koschmieder S.; Carli G.; Cuevas B.; Hernandez-Boluda J.C.; Abadia E.L.; Cirici B.X.; Guglielmelli P.; Garrote M.; Cattaneo D.; Daffini R.; Cavalca F.; Bellosillo B.; Benajiba L.; Curto-Garcia N.; Bellini M.; Betti S.; Harrison C.; Rambaldi A.; Vannucchi A.M. (2021). Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19. BLOOD CANCER JOURNAL, vol. 11, pp. 21-31, ISSN:2044-5385
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Cervantes, Francisco; Ross, David M; Radinoff, Atanas; Palandri, Francesca; Myasnikov, Alexandr; Vannucchi, Alessandro M; Zachee, Pierre; Gisslinger, Heinz; Komatsu, Norio; Foltz, Lynda; Mannelli, Francesco; Passamonti, Francesco; Gilotti, Geralyn; Sadek, Islam; Tiwari, Ranjan; Zor, Evren; Al-Ali, Haifa Kathrin (2021). Correction: Efficacy and safety of a novel dosing strategy for ruxolitinib in the treatment of patients with myelofibrosis and anemia: the REALISE phase 2 study. LEUKEMIA, vol. 35, pp. 3626-3626, ISSN:0887-6924
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Pardanani A.; Tefferi A.; Masszi T.; Mishchenko E.; Drummond M.; Jourdan E.; Vannucchi A.; Jurgutis M.; Ribrag V.; Rambaldi A.; Koh L.P.; Rose S.; Zhang J.; Harrison C. (2021). Updated results of the placebo-controlled, phase III JAKARTA trial of fedratinib in patients with intermediate-2 or high-risk myelofibrosis. BRITISH JOURNAL OF HAEMATOLOGY, vol. 195, pp. 244-248, ISSN:0007-1048
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Harrison C.N.; Schaap N.; Vannucchi A.M.; Kiladjian J.-J.; Jourdan E.; Silver R.T.; Schouten H.C.; Passamonti F.; Zweegman S.; Talpaz M.; Verstovsek S.; Tang D.; Abraham P.; Lord-Bessen J.; Rose S.; Guo S.; Liao W.; Mesa R.A. (2021). Fedratinib Improves Myelofibrosis-related Symptoms and Health-related Quality of Life in Patients with Myelofibrosis Previously Treated with Ruxolitinib: Patient-reported Outcomes from the Phase II JAKARTA2 Trial. HEMASPHERE, vol. 5, pp. 1-11, ISSN:2572-9241
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Piccini, Matteo; Pilerci, Sofia; Merlini, Marta; Grieco, Pietro; Scappini, Barbara; Bencini, Sara; Peruzzi, Benedetta; Caporale, Roberto; Signori, Leonardo; Pancani, Fabiana; Vannucchi, Alessandro Maria; Gianfaldoni, Giacomo (2021). Venetoclax-Based Regimens for Relapsed/Refractory Acute Myeloid Leukemia in a Real-Life Setting: A Retrospective Single-Center Experience. JOURNAL OF CLINICAL MEDICINE, vol. 10, pp. 1684-1695, ISSN:2077-0383
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Vannucchi A.M. (2020). To be, or not to be. BLOOD, vol. 135, pp. 1617-1618, ISSN:0006-4971
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Calvani, Maura; Dabraio, Annalisa; Bruno, Gennaro; De Gregorio, Veronica; Coronnello, Marcella; Bogani, Costanza; Ciullini, Sara; Marca, Giancarlo la; Vignoli, Marina; Chiarugi, Paola; Nardi, Margherita; Vannucchi, Alessandro Maria; Filippi, Luca; Favre, Claudio (2020). β3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 1-18, ISSN:1422-0067
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Loscocco G.G.; Mannelli F.; Mannelli L.; Vergoni F.; Gesullo F.; Rotunno G.; Guglielmelli P.; Vannucchi A.M. (2020). A case of aleukemic mast cell leukemia with an underlying myeloproliferative neoplasm: Morphological and molecular characteristics of a highly aggressive disease. AMERICAN JOURNAL OF HEMATOLOGY, vol. 95, pp. 1622-1624, ISSN:0361-8609
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Tefferi A.; Guglielmelli P.; Lasho T.L.; Coltro G.; Finke C.M.; Loscocco G.G.; Sordi B.; Szuber N.; Rotunno G.; Pacilli A.; Hanson C.A.; Ketterling R.P.; Pardanani A.; Gangat N.; Vannucchi A.M. (2020). Mutation-enhanced international prognostic systems for essential thrombocythaemia and polycythaemia vera. BRITISH JOURNAL OF HAEMATOLOGY, vol. 189, pp. 291-302, ISSN:0007-1048
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Sant'Antonio E.; Guglielmelli P.; Pieri L.; Primignani M.; Randi M.L.; Santarossa C.; Rumi E.; Cervantes F.; Delaini F.; Carobbio A.; Betti S.; Rossi E.; Lavi N.; Harrison C.N.; Curto-Garcia N.; Gisslinger H.; Gisslinger B.; Specchia G.; Ricco A.; Vianelli N.; Polverelli N.; Koren-Michowitz M.; Ruggeri M.; Girodon F.; Ellis M.; Iurlo A.; Mannelli F.; Mannelli L.; Sordi B.; Loscocco G.G.; Cazzola M.; De Stefano V.; Barbui T.; Tefferi A.; Vannucchi A.M. (2020). Splanchnic vein thromboses associated with myeloproliferative neoplasms: An international, retrospective study on 518 cases. AMERICAN JOURNAL OF HEMATOLOGY, vol. 95, pp. 156-166, ISSN:0361-8609
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Mannelli L.; Guglielmelli P.; Vannucchi A.M. (2020). Stem cell transplant for the treatment of myelofibrosis. EXPERT REVIEW OF HEMATOLOGY, vol. 13, pp. 363-374, ISSN:1747-4086
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Bartalucci N.; Guglielmelli P.; Vannucchi A.M. (2020). Polycythemia vera: the current status of preclinical models and therapeutic targets. EXPERT OPINION ON THERAPEUTIC TARGETS, vol. 24, pp. 615-628, ISSN:1472-8222
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Guglielmelli P.; Carobbio A.; Rumi E.; De Stefano V.; Mannelli L.; Mannelli F.; Rotunno G.; Coltro G.; Betti S.; Cavalloni C.; Finazzi M.C.; Thiele J.; Cazzola M.; Vannucchi A.M.; Barbui T. (2020). Validation of the IPSET score for thrombosis in patients with prefibrotic myelofibrosis. BLOOD CANCER JOURNAL, vol. 10, pp. 21-28, ISSN:2044-5385
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Loscocco G.G.; Malandrino D.; Barchiesi S.; Berni A.; Poggesi L.; Guglielmelli P.; Vannucchi A.M. (2020). The HScore for secondary hemophagocytic lymphohistiocytosis, calculated without a marrow biopsy, is consistently low in patients with COVID-19. INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, vol. 42, pp. e270-e273, ISSN:1751-5521
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Barbui T.; Vannucchi A.M.; Guglielmelli P.; de Stefano V.; Rambaldi A. (2020). An agenda for future research projects in polycythemia vera and essential thrombocythemia. HAEMATOLOGICA, vol. 105, pp. 1999-2003, ISSN:0390-6078
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Alessandra Carobbio, Paola Guglielmelli, Elisa Rumi, Chiara Cavalloni, Valerio De Stefano, Silvia Betti, Alessandro Rambaldi, Maria Chiara Finazzi, Juergen Thiele, Alessandro M. Vannucchi, Ayalew Tefferi,Tiziano Barbui (2020). A multistate model of survival prediction and event monitoring in prefibrotic myelofibrosis. BLOOD CANCER JOURNAL, vol. 10, pp. 100-107, ISSN:2044-5385
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Guglielmelli P.; Pacilli A.; Coltro G.; Mannelli F.; Mannelli L.; Contini E.; Rotunno G.; Bartalucci N.; Fiaccabrino S.; Sordi B.; Loscocco G.G.; Paoli C.; Vannucchi A.M. (2020). Characteristics and clinical correlates of NFE2 mutations in chronic Myeloproliferative neoplasms. AMERICAN JOURNAL OF HEMATOLOGY, vol. 95, pp. E23-E26, ISSN:0361-8609
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Mora B.; Guglielmelli P.; Rumi E.; Maffioli M.; Barraco D.; Rambaldi A.; Caramella M.; Komrokji R.S.; Kiladjian J.-J.; Gotlib J.; Iurlo A.; Cervantes F.; Devos T.; Palandri F.; De Stefano V.; Ruggeri M.; Silver R.T.; Albano F.; Benevolo G.; Cavalloni C.; Uccella S.; Accetta R.; Siracusa C.; Agnoli S.; Merli M.; Barbui T.; Bertu L.; Cazzola M.; Vannucchi A.M.; Passamonti F. (2020). Impact of bone marrow fibrosis grade in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: A study of the MYSEC group. AMERICAN JOURNAL OF HEMATOLOGY, vol. 95, pp. E1-E3, ISSN:0361-8609
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Loscocco G.G.; Guglielmelli P.; Vannucchi A.M. (2020). Impact of mutational profile on the management of myeloproliferative neoplasms: A short review of the emerging data. ONCOTARGETS AND THERAPY, vol. 13, pp. 12367-12382, ISSN:1178-6930
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Breccia M.; Piciocchi A.; De Stefano V.; Finazzi G.; Iurlo A.; Fazi P.; Soddu S.; Martino B.; Palandri F.; Siragusa S.; Albano F.; Passamonti F.; Vignetti M.; Vannucchi A.M. (2020). COVID-19 in Philadelphia-negative myeloproliferative disorders: a GIMEMA survey. LEUKEMIA, vol. 34, pp. 2813-2814, ISSN:0887-6924
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Gupta V.; Wolleschak D.; Hasselbalch H.; Vannucchi A.M.; Koschmieder S.; Cervantes F.; Li Y.; Dong T.; Wroclawska M.; Bharathy S.; Harrison C. (2020). Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: A phase 1b/2 dose-finding study. BLOOD ADVANCES, vol. 4, pp. 3063-3071, ISSN:2473-9529
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Coltro G.; Rotunno G.; Mannelli L.; Mannarelli C.; Fiaccabrino S.; Romagnoli S.; Bartalucci N.; Ravenda E.; Gelli E.; Sant'Antonio E.; Patnaik M.M.; Tefferi A.; Vannucchi A.M.; Guglielmelli P. (2020). RAS/CBL mutations predict resistance to JAK inhibitors in myelofibrosis and are associated with poor prognostic features. BLOOD ADVANCES, vol. 4, pp. 3677-3687, ISSN:2473-9529
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Coltro, Giacomo; Antelo, Guadalupe; Lasho, Terra L; Finke, Christy M; Pardanani, Animesh; Gangat, Naseema; Carr, Ryan M; Binder, Moritz; Mangaonkar, Abhishek A; Ketterling, Rhett; Fernandez-Zapico, Martin E; Robertson, Keith D; Bosi, Alberto; Vannucchi, Alessandro M; Tefferi, Ayalew; Patnaik, Mrinal M (2020). Phenotypic Correlates and Prognostic Outcomes of TET2 Mutations in Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes: A Comprehensive Study of 504 Adult Patients. AMERICAN JOURNAL OF HEMATOLOGY, pp. 222-230, ISSN:0361-8609
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Coltro, Giacomo; Mannelli, Francesco; Vergoni, Federica; Santi, Raffaella; Massi, Daniela; Siliani, Luisa Margherita; Marzullo, Antonella; Bonifacio, Stefania; Pelo, Elisabetta; Pacilli, Annalisa; Paoli, Chiara; Franci, Annalisa; Calabresi, Laura; Bosi, Alberto; Vannucchi, Alessandro Maria; Guglielmelli, Paola (2020). Extramedullary blastic transformation of primary myelofibrosis in the form of disseminated myeloid sarcoma: a case report and review of the literature. CLINICAL AND EXPERIMENTAL MEDICINE, pp. 203-210, ISSN:1591-8890
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Rocca, Bianca; Tosetto, Alberto; Betti, Silvia; Soldati, Denise; Petrucci, Giovanna; Rossi, Elena; Timillero, Andrea; Cavalca, Viviana; Porro, Benedetta; Iurlo, Alessandra; Cattaneo, Daniele; Bucelli, Cristina; Dragani, Alfredo; Di Ianni, Mauro; Ranalli, Paola; Palandri, Francesca; Vianelli, Nicola; Beggiato, Eloise; Lanzarone, Giuseppe; Ruggeri, Marco; Carli, Giuseppe; Elli, Elena Maria; Carpenedo, Monica; Bertozzi, Irene; Paoli, Chiara; Randi, Maria L; Ricco, Alessandra; Specchia, Giorgina; Vannucchi, Alessandro Maria; Rodeghiero, Francesco; Patrono, Carlo; De Stefano, Valerio (2020). A randomized, double-blind trial of three aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia. BLOOD, pp. 1-33, ISSN:0006-4971
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Harrison C.N.; Schaap N.; Vannucchi A.M.; Kiladjian J.-J.; Jourdan E.; Silver R.T.; Schouten H.C.; Passamonti F.; Zweegman S.; Talpaz M.; Verstovsek S.; Rose S.; Shen J.; Berry T.; Brownstein C.; Mesa R.A. (2020). Fedratinib in patients with myelofibrosis previously treated with ruxolitinib: An updated analysis of the JAKARTA2 study using stringent criteria for ruxolitinib failure. AMERICAN JOURNAL OF HEMATOLOGY, vol. 95, pp. 594-603, ISSN:0361-8609
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Quattrocchi A.; Maiorca C.; Billi M.; Tomassini S.; De Marinis E.; Cenfra N.; Equitani F.; Gentile M.; Ceccherelli A.; Banella C.; Mecarocci S.; Scerpa M.C.; Pisano S.; Pacilli A.; Di Cristofano C.; Mancini M.; Guglielmelli P.; Vannucchi A.M.; Noguera N.; Grignani F.; Cimino G.; Nervi C. (2020). Genetic lesions disrupting calreticulin 3′-untranslated region in JAK2 mutation-negative polycythemia vera. AMERICAN JOURNAL OF HEMATOLOGY, vol. 95, pp. E263-E267, ISSN:0361-8609
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Gerds A.T.; Savona M.R.; Scott B.L.; Talpaz M.; Egyed M.; Harrison C.N.; Yacoub A.; Vannucchi A.; Mead A.J.; Kiladjian J.-J.; O'Sullivan J.; Garcia-Gutierrez V.; Bose P.; Rampal R.K.; Miller C.B.; Palmer J.; Oh S.T.; Buckley S.A.; Mould D.R.; Ito K.; Tyavanagimatt S.; Smith J.A.; Roman-Torres K.; Devineni S.; Craig A.R.; Mascarenhas J.O. (2020). Determining the recommended dose of pacritinib: Results from the PAC203 dose-finding trial in advanced myelofibrosis. BLOOD ADVANCES, vol. 4, pp. 5825-5835, ISSN:2473-9529
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Palandri F.; Piciocchi A.; De Stefano V.; Breccia M.; Finazzi G.; Iurlo A.; Fazi P.; Soddu S.; Martino B.; Siragusa S.; Albano F.; Passamonti F.; Vignetti M.; Vannucchi A.M. (2020). How the coronavirus pandemic has affected the clinical management of Philadelphia-negative chronic myeloproliferative neoplasms in Italy—a GIMEMA MPN WP survey. LEUKEMIA, vol. 34, pp. 2805-2808, ISSN:0887-6924
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Zingariello M.; Rosti V.; Vannucchi A.M.; Guglielmelli P.; Mazzarini M.; Barosi G.; Genova M.L.; Migliaccio A.R. (2020). Shared and Distinctive Ultrastructural Abnormalities Expressed by Megakaryocytes in Bone Marrow and Spleen From Patients With Myelofibrosis. FRONTIERS IN ONCOLOGY, vol. 10, pp. 1-12, ISSN:2234-943X
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Coltro, Giacomo; Mangaonkar, Abhishek A; Lasho, Terra L; Finke, Christy M; Pophali, Prateek; Carr, Ryan; Gangat, Naseema; Binder, Moritz; Pardanani, Animesh; Fernandez-Zapico, Martin; Robertson, Keith D; Bosi, Alberto; Droin, Nathalie; Vannucchi, Alessandro M; Tefferi, Ayalew; Hunter, Anthony; Padron, Eric; Solary, Eric; Patnaik, Mrinal M (2019). Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)-a study of 1084 patients. LEUKEMIA, pp. 78-85, ISSN:0887-6924
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Bolognini D.; Bartalucci N.; Mingrino A.; Vannucchi A.M.; Magi A. (2019). NANOR: A user-friendly R package to analyze and compare nanopore sequencing data. PLOS ONE, vol. 14, pp. 1-12, ISSN:1932-6203
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Bridgford, Jessica L; Lee, Su Min; Lee, Christine Mei Mei; Guglielmelli, Paola; Rumi, Elisa; Pietra, Daniela; Wilcox, Stephen; Chhabra, Yash; Rubin, Alan F; Cazzola, Mario; Vannucchi, Alessandro M.; Brooks, Andrew J; Call, Matthew Edwin; Call, Melissa Joy (2019). Novel Drivers and Modifiers of MPL-dependent Oncogenic Transformation Identified by Deep Mutational Scanning. BLOOD, pp. 1-14, ISSN:0006-4971
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Marchetti, Monia; Ghirardi, Arianna; Masciulli, Arianna; Carobbio, Alessandra; Palandri, Francesca; Vianelli, Nicola; Rossi, Elena; Betti, Silvia; Di Veroli, Ambra; Iurlo, Alessandra; Cattaneo, Daniele; Finazzi, Guido; Bonifacio, Massimiliano; Scaffidi, Luigi; Patriarca, Andrea; Rumi, Elisa; Casetti, Ilaria Carola; Stephenson, Clemency; Guglielmelli, Paola; Elli, Elena Maria; Palova, Miroslava; Rapezzi, Davide; Erez, Daniel; Gomez, Montse; Wille, Kai; Perez-Encinas, Manuel; Lunghi, Francesca; Angona, Anna; Fox, Maria Laura; Beggiato, Eloise; Benevolo, Giulia; Carli, Giuseppe; Cacciola, Rossella; McMullin, Mary Frances; Tieghi, Alessia; Recasens, Valle; Isfort, Susanne; Pane, Fabrizio; De Stefano, Valerio; Griesshammer, Martin; Alvarez-Larran, Alberto; Vannucchi, Alessandro Maria; Rambaldi, Alessandro; Barbui, Tiziano (2019). Second cancers in MPN: Survival analysis from an international study. AMERICAN JOURNAL OF HEMATOLOGY, pp. 1-19, ISSN:0361-8609
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Barbui T.; De Stefano V.; Falanga A.; Finazzi G.; Martinelli I.; Rodeghiero F.; Vannucchi A.M.; Barosi G. (2019). Addressing and proposing solutions for unmet clinical needs in the management of myeloproliferative neoplasm-associated thrombosis: A consensus-based position paper. BLOOD CANCER JOURNAL, vol. 9, pp. 1-10, ISSN:2044-5385
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Vannucchi A.M.; Te Boekhorst P.A.W.; Harrison C.N.; He G.; Caramella M.; Niederwieser D.; Boyer-Perrard F.; Duan M.; Francillard N.; Molloy B.; Wroclawska M.; Gisslinger H. (2019). EXPAND, a dose-finding study of ruxolitinib in patients with myelofibrosis and low platelet counts: 48-week follow-up analysis. HAEMATOLOGICA, vol. 104, pp. 947-954, ISSN:0390-6078
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Barbui T.; Thiele J.; Gisslinger H.; Orazi A.; Vannucchi A.M.; Gianelli U.; Beham-Schmid C.; Tefferi A. (2019). Comments on pre-fibrotic myelofibrosis and how should it be managed. BRITISH JOURNAL OF HAEMATOLOGY, vol. 186, pp. 358-360, ISSN:0007-1048
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Ferrari, Alberto; Carobbio, Alessandra; Masciulli, Arianna; Ghirardi, Arianna; Finazzi, Guido; De Stefano, Valerio; Vannucchi, Alessandro Maria; Barbui, Tiziano (2019). Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis. HAEMATOLOGICA, pp. 1-19, ISSN:0390-6078
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Barbui, Tiziano; Ghirardi, Arianna; Masciulli, Arianna; Carobbio, Alessandra; Palandri, Francesca; Vianelli, Nicola; De Stefano, Valerio; Betti, Silvia; Di Veroli, Ambra; Iurlo, Alessandra; Cattaneo, Daniele; Delaini, Federica; Bonifacio, Massimiliano; Scaffidi, Luigi; Patriarca, Andrea; Rumi, Elisa; Casetti, Ilaria Carola; Stephenson, Clemency; Guglielmelli, Paola; Elli, Elena Maria; Palova, Miroslava; Bertolotti, Laura; Erez, Daniel; Gomez, Montse; Wille, Kai; Perez-Encinas, Manuel; Lunghi, Francesca; Angona, Anna; Fox, Maria Laura; Beggiato, Eloise; Benevolo, Giulia; Carli, Giuseppe; Cacciola, Rossella; McMullin, Mary Frances; Tieghi, Alessia; Recasens, Valle; Marchetti, Monia; Griesshammer, Martin; Alvarez-Larran, Alberto; Vannucchi, Alessandro Maria; Finazzi, Guido (2019). Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study. LEUKEMIA, vol. 33, pp. 1996-2005, ISSN:1476-5551
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Mannelli F.; Gesullo F.; Rotunno G.; Pacilli A.; Bencini S.; Annunziato F.; Zanotti R.; Scaffidi L.; Giona F.; Santopietro M.; Grifoni F.; Pieri L.; Guglielmelli P.; Vannucchi A.M. (2019). Myelodysplasia as assessed by multiparameter flow cytometry refines prognostic stratification provided by genotypic risk in systemic mastocytosis. AMERICAN JOURNAL OF HEMATOLOGY, vol. 94, pp. 845-852, ISSN:0361-8609
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Rotunno G.; Mannarelli C.; Brogi G.; Pacilli A.; Gesullo F.; Mannelli F.; Fiaccabrino S.; Sordi B.; Paoli C.; Marone I.; Rumi E.; Manfredini R.; Barosi G.; Cazzola M.; Vannucchi A.M.; Guglielmelli P. (2019). Spectrum of ASXL1 mutations in primary myelofibrosis: Prognostic impact of the ASXL1 p.G646Wfs∗12 mutation. BLOOD, vol. 133, pp. 2802-2808, ISSN:0006-4971
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Salati S.; Genovese E.; Carretta C.; Zini R.; Bartalucci N.; Prudente Z.; Pennucci V.; Ruberti S.; Rossi C.; Rontauroli S.; Enzo E.; Calabresi L.; Balliu M.; Mannarelli C.; Bianchi E.; Guglielmelli P.; Tagliafico E.; Vannucchi A.M.; Manfredini R. (2019). Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants. SCIENTIFIC REPORTS, vol. 9, pp. 10558-10571, ISSN:2045-2322
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Loscocco G.G.; Mannelli F.; Guglielmelli P.; Paoli C.; Marone I.; Cucci R.; Coltro G.; Sordi B.; Albano F.; Breccia M.; De Stefano V.; Finazzi G.; Iurlo A.; Martino B.; Palandri F.; Passamonti F.; Siragusa S.; Mannelli L.; Fantoni D.; Fazi P.; Amadori S.; Vignetti M.; Barbui T.; Vannucchi A.M. (2019). Italian survey on clinical practice in myeloproliferative neoplasms. A GIMEMA Myeloproliferative Neoplasms Working Party initiative. AMERICAN JOURNAL OF HEMATOLOGY, vol. 94, pp. E239-E242, ISSN:0361-8609
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Vannucchi A.M.; Guglielmelli P. (2019). The JAK2 46/1 (GGCC) MPN-predisposing haplotype: A risky haplotype, after all. AMERICAN JOURNAL OF HEMATOLOGY, vol. 94, pp. 283-285, ISSN:0361-8609
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Magi, Alberto; Bolognini, Davide; Bartalucci, Niccoló; Mingrino, Alessandra; Semeraro, Roberto; Giovannini, Luna; Bonifacio, Stefania; Parrini, Daniela; Pelo, Elisabetta; Mannelli, Francesco; Guglielmelli, Paola; Vannucchi, Alessandro Maria (2019). Nano-GLADIATOR: real-time detection of copy number alterations from nanopore sequencing data. BIOINFORMATICS, pp. 1-9, ISSN:1367-4803
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Molin A.D.; Bresolin S.; Gaffo E.; Tretti C.; Boldrin E.; Meyer L.H.; Guglielmelli P.; Vannucchi A.M.; Kronnie G.; Bortoluzzi S. (2019). Circ RNAs are here to stay: A perspective on the MLL recombinome. FRONTIERS IN GENETICS, vol. 10, pp. 88-95, ISSN:1664-8021
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Mora B.; Rumi E.; Guglielmelli P.; Barraco D.; Maffioli M.; Rambaldi A.; Caramella M.; Komrokji R.; Gotlib J.; Kiladjian J.J.; Cervantes F.; Devos T.; Palandri F.; Stefano V.D.; Ruggeri M.; Silver R.T.; Benevolo G.; Albano F.; Cavalloni C.; Pietra D.; Barbui T.; Rotunno G.; Cazzola M.; Vannucchi A.M.; Giorgino T.; Passamonti F. (2019). Second primary malignancies in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 2233 patients. CANCER MEDICINE, vol. 8, pp. 4089-4092, ISSN:2045-7634
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Paola Guglielmelli, MD PhD, Niccolò Bartalucci, PhDBSc, Elisa Contini, PhD, Giada Rotunno, PhD, Annalisa Pacilli, PhD, Simone Romagnoli, BSc, Lara Mannelli, MD, Francesco Mannelli, MD, Giacomo Coltro, MD, Alessandro Pancrazzi, PhD, Valentina Ariu, BSci, Sara Fiaccabrino, Roberto Semeraro, Alberto Magi, PhD, Carmela Mannarelli, PhD, Francesca Gesullo, BSci, Chiara Paoli, PhD, Alessandro M. Vannucchi, MD (2019). Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs). BLOOD, pp. 0-0, ISSN:0006-4971
Bartalucci, N; Mannelli, F; Contini, E; Romagnoli, S; Gianfaldoni, G; Scappini, B; Pelo, E; Pancani, F; Magi, A; Bosi, A; Guglielmelli, P; Vannucchi, AM (2019). THIRD GENERATION SEQUENCING OF NORMAL KARYOTYPE ACUTE MYELOID LEUKEMIA: IMPLICATIONS FOR PROGNOSIS. In: HAEMATOLOGICA, FERRATA STORTI FOUNDATION, vol. 104, pp. 12-12.
Yacoub, Abdulraheem; Mascarenhas, John; Kosiorek, Heidi; Prchal, Josef T.; Berenzon, Dmitry; Baer, Maria R.; Ritchie, Ellen; Silver, Richard T.; Kessler, Craig; Winton, Elliott; Finazzi, Maria Chiara; Rambaldi, Alessandro; Vannucchi, Alessandro M.; Leibowitz, David; Rondelli, Damiano; Arcasoy, Murat O.; Catchatourian, Rosalind; Vadakara, Joseph; Rosti, Vittorio; Hexner, Elizabeth; Kremyanskaya, Marina; Sandy, Lonette; Tripodi, Joseph; Najfeld, Vesna; Farnoud, Noushin; Papaemmanuil, Elli; Salama, Mohamed; Singer-Weinberg, Rona; Rampal, Raajit; Goldberg, Judith D.; Barbui, Tiziano; Mesa, Ruben; Dueck, Amylou C.; Hoffman, Ronald (2019). Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea. BLOOD, vol. 134, pp. 1498-1509, ISSN:0006-4971
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Mannelli F.; Gesullo F.; Rotunno G.; Pacilli A.; Pieri L.; Guglielmelli P.; Vannucchi A.M. (2019). Validation of the Mayo alliance prognostic system for mastocytosis. BLOOD CANCER JOURNAL, vol. 9, pp. 18-21, ISSN:2044-5385
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Bartalucci, Niccolò; Romagnoli, Simone; Contini, Elisa; Marseglia, Giuseppina; Magi, Alberto; Guglielmelli, Paola; Pelo, Elisabetta; Vannucchi, Alessandro M (2019). Long Reads, Short Time: Feasibility of Prenatal Sample Karyotyping by Nanopore Genome Sequencing. CLINICAL CHEMISTRY, vol. 65, pp. 1605-1608-1608, ISSN:0009-9147
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Barbui, Tiziano; Thiele, Jürgen; Gisslinger, Heinz; Kvasnicka, Hans Michael; Vannucchi, Alessandro M; Guglielmelli, Paola; Orazi, Attilio; Tefferi, Ayalew (2018). The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussion. BLOOD CANCER JOURNAL, vol. 8, pp. 15-25, ISSN:2044-5385
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Tefferi, Ayalew; Mudireddy, Mythri; Mannelli, Francesco; Begna, Kebede H; Patnaik, Mrinal M; Hanson, Curtis A; Ketterling, Rhett P; Gangat, Naseema; Yogarajah, Meera; De Stefano, Valerio; Passamonti, Francesco; Rosti, Vittorio; Finazzi, Maria Chiara; Rambaldi, Alessandro; Bosi, Alberto; Guglielmelli, Paola; Pardanani, Animesh; Vannucchi, Alessandro M (2018). Blast phase myeloproliferative neoplasm: Mayo-AGIMM study of 410 patients from two separate cohorts. LEUKEMIA, pp. 280-290, ISSN:1476-5551
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Loscocco, Giuseppe G; Piccini, Matteo; Vergoni, Federica; Vannucchi, Alessandro M; Bosi, Alberto (2018). A case of disseminated Blastic Plasmocytoid Dendritic Cell Neoplasm. AMERICAN JOURNAL OF HEMATOLOGY, pp. 25-28, ISSN:0361-8609
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Tefferi, Ayalew*; Vannucchi, Alessandro M.; Barbui, Tiziano (2018). Essential thrombocythemia treatment algorithm 2018. BLOOD CANCER JOURNAL, vol. 8, pp. 2-7, ISSN:2044-5385
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Tefferi, Ayalew*; Vannucchi, Alessandro M.; Barbui, Tiziano (2018). Polycythemia vera treatment algorithm 2018. BLOOD CANCER JOURNAL, vol. 8, pp. 3-9, ISSN:2044-5385
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Barosi G.; Passamonti F.; Accorsi P.; Pane F.; Vannucchi A.M.; Velati C.; Gale R.P.; Tura S.; Barbui T. (2018). Response to “Questions arising on phlebotomy in polycythemia vera: prophylactic measures to reduce thromboembolic events require patient-focused decisions” by Heidel et al. LEUKEMIA, vol. 32, pp. 2727-2728, ISSN:0887-6924
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Barbui T.; Passamonti F.; Accorsi P.; Pane F.; Vannucchi A.M.; Velati C.; Gale R.P.; Tura S.; Barosi G. (2018). Evidence- and consensus-based recommendations for phlebotomy in polycythemia vera. LEUKEMIA, vol. 32, pp. 2077-2081, ISSN:0887-6924
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De Stefano V.; Rossi E.; Carobbio A.; Ghirardi A.; Betti S.; Finazzi G.; Vannucchi A.M.; Barbui T. (2018). Hydroxyurea prevents arterial and late venous thrombotic recurrences in patients with myeloproliferative neoplasms but fails in the splanchnic venous district. Pooled analysis of 1500 cases. BLOOD CANCER JOURNAL, vol. 8, pp. 112-118, ISSN:2044-5385
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Barbui T.; Finazzi G.; Vannucchi A.M.; De Stefano V. (2018). Targeting myeloid cells to prevent recurrent stroke in general population: the lesson of hydroxyurea in myeloproliferative neoplasms. BLOOD CANCER JOURNAL, vol. 8, pp. 103-105, ISSN:2044-5385
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Barbui T.; De Stefano V.; Ghirardi A.; Masciulli A.; Finazzi G.; Vannucchi A.M. (2018). Different effect of hydroxyurea and phlebotomy on prevention of arterial and venous thrombosis in Polycythemia Vera. BLOOD CANCER JOURNAL, vol. 8, pp. 1-4, ISSN:2044-5385
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Tefferi A.; Guglielmelli P.; Lasho T.L.; Gangat N.; Ketterling R.P.; Pardanani A.; Vannucchi A.M. (2018). MIPSS701 version 2.0: Mutation and karyotype-enhanced international prognostic scoring system for primary myelofibrosis. JOURNAL OF CLINICAL ONCOLOGY, vol. 36, pp. 1769-1770, ISSN:0732-183X
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Mora B.; Giorgino T.; Guglielmelli P.; Rumi E.; Maffioli M.; Rambaldi A.; Caramella M.; Komrokji R.; Gotlib J.; Kiladjian J.J.; Cervantes F.; Devos T.; Palandri F.; De Stefano V.; Ruggeri M.; Silver R.T.; Benevolo G.; Albano F.; Cavalloni C.; Barraco D.; Merli M.; Pietra D.; Casalone R.; Barbui T.; Rotunno G.; Cazzola M.; Vannucchi A.M.; Passamonti F. (2018). Value of cytogenetic abnormalities in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: A study of the MYSEC project. HAEMATOLOGICA, vol. 103, pp. e392-e394, ISSN:0390-6078
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Rossi C.; Zini R.; Rontauroli S.; Ruberti S.; Prudente Z.; Barbieri G.; Bianchi E.; Salati S.; Genovese E.; Bartalucci N.; Guglielmelli P.; Tagliafico E.; Rosti V.; Barosi G.; Vannucchi A.M.; Manfredini R. (2018). Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis. MOLECULAR ONCOLOGY, vol. 12, pp. 2102-2123, ISSN:1574-7891
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Grinfeld J.; Nangalia J.; Baxter E.J.; Wedge D.C.; Angelopoulos N.; Cantrill R.; Godfrey A.L.; Papaemmanuil E.; Gundem G.; MacLean C.; Cook J.; O'Neil L.; O'Meara S.; Teague J.W.; Butler A.P.; Massie C.E.; Williams N.; Nice F.L.; Andersen C.L.; Hasselbalch H.C.; Guglielmelli P.; McMullin M.F.; Vannucchi A.M.; Harrison C.N.; Gerstung M.; Green A.R.; Campbell P.J. (2018). Classification and personalized prognosis in myeloproliferative neoplasms. THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 379, pp. 1416-1430, ISSN:0028-4793
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Pacilli A.; Rotunno G.; Mannarelli C.; Fanelli T.; Pancrazzi A.; Contini E.; Mannelli F.; Gesullo F.; Bartalucci N.; Fattori G.C.; Paoli C.; Vannucchi A.M.; Guglielmelli P. (2018). Mutation landscape in patients with myelofibrosis receiving ruxolitinib or hydroxyurea. BLOOD CANCER JOURNAL, vol. 8, pp. 122-131, ISSN:2044-5385
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Mora B.; Giorgino T.; Guglielmelli P.; Rumi E.; Maffioli M.; Rambaldi A.; Caramella M.; Komrokji R.; Gotlib J.; Kiladjian J.J.; Cervantes F.; Devos T.; Palandri F.; De Stefano V.; Ruggeri M.; Silver R.T.; Benevolo G.; Albano F.; Cavalloni C.; Barraco D.; Pietra D.; Barbui T.; Rotunno G.; Vannucchi A.M.; Passamonti F. (2018). Phenotype variability of patients with post polycythemia vera and post essential thrombocythemia myelofibrosis is associated with the time to progression from polycythemia vera and essential thrombocythemia. LEUKEMIA RESEARCH, vol. 69, pp. 100-102, ISSN:0145-2126
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Barraco D.; Mora B.; Guglielmelli P.; Rumi E.; Maffioli M.; Rambaldi A.; Caramella M.; Komrokji R.; Gotlib J.; Kiladjian J.J.; Cervantes F.; Devos T.; Palandri F.; De Stefano V.; Ruggeri M.; Silver R.T.; Benevolo G.; Albano F.; Merli M.; Pietra D.; Barbui T.; Rotunno G.; Cazzola M.; Giorgino T.; Vannucchi A.M.; Passamonti F. (2018). Gender effect on phenotype and genotype in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis: results from the MYSEC project. BLOOD CANCER JOURNAL, vol. 8, pp. 89-92, ISSN:2044-5385
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Pardanani A.; Shah S.; Mannelli F.; Elala Y.C.; Guglielmelli P.; Lasho T.L.; Patnaik M.M.; Gangat N.; Ketterling R.P.; Reichard K.K.; Hanson C.A.; Vannucchi A.M.; Tefferi A. (2018). Mayo alliance prognostic system for mastocytosis: Clinical and hybrid clinical-molecular models. BLOOD ADVANCES, vol. 2, pp. 2964-2972, ISSN:2473-9529
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Tefferi A.; Guglielmelli P.; Pardanani A.; Vannucchi A.M. (2018). Myelofibrosis Treatment Algorithm 2018. BLOOD CANCER JOURNAL, vol. 8, pp. 72-78, ISSN:2044-5385
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De Stefano V.; Carobbio A.; Di Lazzaro V.; Guglielmelli P.; Iurlo A.; Finazzi M.C.; Rumi E.; Cervantes F.; Elli E.M.; Randi M.L.; Griesshammer M.; Palandri F.; Bonifacio M.; Hernandez-Boluda J.-C.; Cacciola R.; Miroslava P.; Carli G.; Beggiato E.; Ellis M.H.; Musolino C.; Gaidano G.; Rapezzi D.; Tieghi A.; Lunghi F.; Loscocco G.G.; Cattaneo D.; Cortelezzi A.; Betti S.; Rossi E.; Finazzi G.; Censori B.; Cazzola M.; Bellini M.; Arellano-Rodrigo E.; Bertozzi I.; Sadjadian P.; Vianelli N.; Scaffidi L.; Gomez M.; Cacciola E.; Vannucchi A.M.; Barbui T. (2018). Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms. BLOOD CANCER JOURNAL, vol. 8, pp. 25-36, ISSN:2044-5385
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Tefferi, Ayalew; Guglielmelli, Paola; Nicolosi, Maura; Mannelli, Francesco; Mudireddy, Mythri; Bartalucci, Niccolo; Finke, Christy M; Lasho, Terra L; Hanson, Curtis A; Ketterling, Rhett P; Begna, Kebede H; Naseema Gangat, null; Pardanani, Animesh; Vannucchi, Alessandro M (2018). GIPSS: genetically inspired prognostic scoring system for primary myelofibrosis. LEUKEMIA, vol. 32, pp. 1631-1642, ISSN:1476-5551
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Chorzalska A.; Morgan J.; Ahsan N.; Treaba D.O.; Olszewski A.J.; Petersen M.; Kingston N.; Cheng Y.; Lombardo K.; Schorl C.; Yu X.; Zini R.; Pacilli A.; Tepper A.; Coburn J.; Hryniewicz-Jankowska A.; Zhao T.C.; Oancea E.; Reagan J.L.; Liang O.; Kotula L.; Quesenberry P.J.; Gruppuso P.A.; Manfredini R.; Vannucchi A.M.; Dubielecka P.M. (2018). Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling, human myelofibrosis. BLOOD, vol. 132, pp. 2053-2066, ISSN:0006-4971
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De Stefano V.; Rocca B.; Tosetto A.; Soldati D.; Petrucci G.; Beggiato E.; Bertozzi I.; Betti S.; Carli G.; Carpenedo M.; Cattaneo D.; Cavalca V.; Dragani A.; Elli E.; Finazzi G.; Iurlo A.; Lanzarone G.; Lissandrini L.; Palandri F.; Paoli C.; Rambaldi A.; Ranalli P.; Randi M.L.; Ricco A.; Rossi E.; Ruggeri M.; Specchia G.; Timillero A.; Turnu L.; Vianelli N.; Vannucchi A.M.; Rodeghiero F.; Patrono C. (2018). The Aspirin Regimens in Essential Thrombocythemia (ARES) phase II randomized trial design: Implementation of the serum thromboxane B 2 assay as an evaluation tool of different aspirin dosing regimens in the clinical setting. BLOOD CANCER JOURNAL, vol. 8, pp. 49-57, ISSN:2044-5385
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Finazzi G.; Vannucchi A.M.; Barbui T. (2018). Prefibrotic myelofibrosis: treatment algorithm 2018. BLOOD CANCER JOURNAL, vol. 8, pp. 104-108, ISSN:2044-5385
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Barbui T.; Tefferi A.; Vannucchi A.M.; Passamonti F.; Silver R.T.; Hoffman R.; Verstovsek S.; Mesa R.; Kiladjian J.-J.; Hehlmann R.; Reiter A.; Cervantes F.; Harrison C.; Mc Mullin M.F.; Hasselbalch H.C.; Koschmieder S.; Marchetti M.; Bacigalupo A.; Finazzi G.; Kroeger N.; Griesshammer M.; Birgegard G.; Barosi G. (2018). Philadelphia chromosome-negative classical myeloproliferative neoplasms: Revised management recommendations from European LeukemiaNet. LEUKEMIA, vol. 32, pp. 1057-1069, ISSN:0887-6924
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Avanzini, Maria Antonietta; Abbonante, Vittorio; Catarsi, Paolo; Dambruoso, Irene; Mantelli, Melissa; Poletto, Valentina; Lenta, Elisa; Guglielmelli, Paola; Croce, Stefania; Cobianchi, Lorenzo; Jemos, Basilio; Campanelli, Rita; Bonetti, Elisa; Di Buduo, Christian Andrea; Salmoiraghi, Silvia; Villani, Laura; Massa, Margherita; Boni, Marina; Zappatore, Rita; Iurlo, Alessandra; Rambaldi, Alessandro; Vannucchi, Alessandro Maria; Bernasconi, Paolo; Balduini, Alessandra; Barosi, Giovanni; Rosti, Vittorio* (2018). The spleen of patients with myelofibrosis harbors defective mesenchymal stromal cells. AMERICAN JOURNAL OF HEMATOLOGY, pp. 00-23, ISSN:0361-8609
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Passamonti, F.; Giorgino, T.; Mora, B.; Guglielmelli, P.; Rumi, E.; Maffioli, M.; Rambaldi, A.; Caramella, M.; Komrokji, R.; Gotlib, J.; Kiladjian, J. J.; Cervantes, F.; Devos, T.; Palandri, F.; De Stefano, V.; Ruggeri, M.; Silver, R. T.; Benevolo, G.; Albano, F.; Caramazza, D.; Merli, M.; Pietra, D.; Casalone, R.; Rotunno, G.; Barbui, T.; Cazzola, M.; Vannucchi, A. M. (2017). A clinical-molecular prognostic model to predict survival in patients with post polycythemia vera and post essential thrombocythemia myelofibrosis. LEUKEMIA, vol. 31, pp. 2726-2731, ISSN:0887-6924
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Guglielmelli, Paola; Lasho, Terra L; Rotunno, Giada; Mudireddy, Mythri; Mannarelli, Carmela; Nicolosi, Maura; Pacilli, Annalisa; Pardanani, Animesh; Rumi, Elisa; Rosti, Vittorio; Hanson, Curtis A; Mannelli, Francesco; Ketterling, Rhett P; Gangat, Naseema; Rambaldi, Alessandro; Passamonti, Francesco; Barosi, Giovanni; Barbui, Tiziano; Cazzola, Mario; Vannucchi, Alessandro M; Tefferi, Ayalew (2017). MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis. JOURNAL OF CLINICAL ONCOLOGY, vol. 36, pp. 310-318, ISSN:0732-183X
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Ruberti, S; Bianchi, E; Guglielmelli, P; Rontauroli, S; Barbieri, G; Tavernari, L; Fanelli, T; Norfo, R; Pennucci, V; G. Corbizi, Fattori; Mannarelli, C; Bartalucci, N; Mora, B; Elli, L; Avanzini, M. A; Rossi, C; Salmoiraghi, S; Zini, R; Salati, S; Prudente, Z; Rosti, V; Passamonti, F; Rambaldi, A; Ferrari, S; Tagliafico, E; Vannucchi, A. M; Manfredini, R. (2017). Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients. LEUKEMIA, pp. 00-01, ISSN:0887-6924
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Vannucchi, Alessandro M; Guglielmelli, Paola; Tefferi, Ayalew (2017). Polycythemia vera and essential thrombocythemia: algorithmic approach. CURRENT OPINION IN HEMATOLOGY, pp. 00-01, ISSN:1065-6251
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Bartalucci, Niccolã²; Calabresi, Laura; Balliu, Manjola; Martinelli, Serena; Rossi, Maria Caterina; Villeval, Jean Luc; Annunziato, Francesco; Guglielmelli, Paola; Vannucchi, Alessandro M. (2017). Inhibitors of the PI3K/mTOR pathway prevent STAT5 phosphorylation in JAK2V617F mutated cells through PP2A/ CIP2A axis. ONCOTARGET, vol. 8, pp. 96710-96724, ISSN:1949-2553
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Ellis, Martin H.; Koren-Michowitz, Maya; Lavi, Noa; Vannucchi, Alessandro M; Mesa, Ruben; Harrison, Claire N. (2017). Ruxolitinib for the management of myelofibrosis: Results of an international physician survey. LEUKEMIA RESEARCH, vol. 61, pp. 6-9, ISSN:0145-2126
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Tefferi, Ayalew; Betti, Silvia; Barraco, Daniela; Mudireddy, Mythri; Shah, Sahrish; Hanson, Curtis A.; Ketterling, Rhett P.; Pardanani, Animesh; Gangat, Naseema; Coltro, Giacomo; Guglielmelli, Paola; Vannucchi, Alessandro M. (2017). Gender and survival in essential thrombocythemia: A two-center study of 1,494 patients. AMERICAN JOURNAL OF HEMATOLOGY, vol. 92, pp. 1193-1197, ISSN:0361-8609
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Erba, Benedetta Gaia; Gruppi, Cristian; Corada, Monica; Pisati, Federica; Rosti, Vittorio; Bartalucci, Niccoloâ ; Villeval, Jean-Luc; Vannucchi, Alessandro Maria; Barosi, Giovanni; Balduini, Alessandra; Dejana, Elisabetta (2017). Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis. THE AMERICAN JOURNAL OF PATHOLOGY, vol. 187, pp. 1879-1892, ISSN:0002-9440
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Verstovsek, Srdan; Passamonti, Francesco; Rambaldi, Alessandro; Barosi, Giovanni; Rumi, Elisa; Gattoni, Elisabetta; Pieri, Lisa; Zhen, Huiling; Granier, Muriel; Assad, Albert; Cazzola, Mario; Kantarjian, Hagop M.; Barbui, Tiziano; Vannucchi, Alessandro M. (2017). Ruxolitinib for essential thrombocythemia refractory to or intolerant of hydroxyurea: long-term phase 2 study results. BLOOD, vol. 130, pp. 1768-1771, ISSN:0006-4971
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Harrison, Claire N; Schaap, Nicolaas; Vannucchi, Alessandro M; Kiladjian, Jean-Jacques; Tiu, Ramon V; Zachee, Pierre; Jourdan, Eric; Winton, Elliott; Silver, Richard T; Schouten, Harry C; Passamonti, Francesco; Zweegman, Sonja; Talpaz, Moshe; Lager, Joanne; Shun, Zhenming; Mesa, Ruben A. (2017). Janus kinase-2 inhibitor fedratinib in patients with myelofibrosis previously treated with ruxolitinib (JAKARTA-2): a single-arm, open-label, non-randomised, phase 2, multicentre study. THE LANCET. HAEMATOLOGY, vol. 4, pp. e317-e324, ISSN:2352-3026
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Barbui, Tiziano; Vannucchi, Alessandro Maria; Finazzi, Guido; Finazzi, Maria Chiara; Masciulli, Arianna; Carobbio, Alessandra; Ghirardi, Arianna; Tognoni, Gianni (2017). A reappraisal of the benefit-risk profile of hydroxyurea in polycythemia vera: A propensity-matched study. AMERICAN JOURNAL OF HEMATOLOGY, vol. 92, pp. 1131-1136, ISSN:0361-8609
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Vannucchi, Alessandro M.; Guglielmelli, Paola (2017). Traffic lights for ruxolitinib. BLOOD, vol. 130, pp. 1075-1077, ISSN:0006-4971
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Tefferi, Ayalew; Nicolosi, Maura; Mudireddy, Mythri; Szuber, Natasha; Finke, Christy M.; Lasho, Terra L.; Hanson, Curtis A.; Ketterling, Rhett P.; Pardanani, Animesh; Gangat, Naseema; Mannarelli, Carmela; Fanelli, Tiziana; Guglielmelli, Paola; Vannucchi, Alessandro M. (2017). Driver mutations and prognosis in primary myelofibrosis: Mayo-Careggi MPN alliance study of 1,095 patients. AMERICAN JOURNAL OF HEMATOLOGY, pp. 00-01, ISSN:0361-8609
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Kvasnicka, Hans Michael; Orazi, Attilio; Thiele, Juergen; Barosi, Giovanni; Bueso-Ramos, Carlos E.; Vannucchi, Alessandro M.; Hasserjian, Robert P.; Kiladjian, Jean-Jacques; Gianelli, Umberto; Silver, Richard; Mughal, Tariq I.; Barbui, Tiziano (2017). European LeukemiaNet study on the reproducibility of bone marrow features in masked polycythemia vera and differentiation from essential thrombocythemia. AMERICAN JOURNAL OF HEMATOLOGY, vol. 92, pp. 1062-1067, ISSN:0361-8609
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Vannucchi, Alessandro M.; Guglielmelli, Paola (2017). What are the current treatment approaches for patients with polycythemia vera and essential thrombocythemia?. HEMATOLOGY, vol. 2017, pp. 480-488, ISSN:1520-4391
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Scotch, Allison H.; Kosiorek, Heidi; Scherber, Robyn; Dueck, Amylou C.; Slot, Stefanie; Zweegman, Sonja; Boekhorst, Peter A. W. te; Commandeur, Suzan; Schouten, Harry; Sackmann, Federico; Fuentes, Ana Kerguelen; Hernández-Maraver, Dolores; Pahl, Heike L.; Griesshammer, Martin; Stegelmann, Frank; Dã¶hner, Konstanze; Lehmann, Thomas; Bonatz, Karin; Reiter, Andreas; Boyer, Francoise; Etienne, Gabriel; Ianotto, Jean-Christophe; Ranta, Dana; Roy, Lydia; Cahn, Jean-Yves; Harrison, Claire N.; Radia, Deepti; Muxi, Pablo; Maldonado, Norman; Besses, Carlos; Cervantes, Francisco; Johansson, Peter L.; Barbui, Tiziano; Barosi, Giovanni; Vannucchi, Alessandro M.; Paoli, Chiara; Passamonti, Francesco; Andreasson, Bjorn; Ferrari, Maria L.; Rambaldi, Alessandro; Samuelsson, Jan; Birgegard, Gunnar; Xiao, Zhijian; Zefeng, Xu; Zhang, Yue; Sun, Xiujuan; Junqing, Xu; Kiladjian, Jean-Jacques; Zhang, Peihong; Gale, Robert Peter; Mesa, Ruben A.; Geyer, Holly L. (2017). Symptom burden profile in myelofibrosis patients with thrombocytopenia: Lessons and unmet needs. LEUKEMIA RESEARCH, vol. 63, pp. 34-40, ISSN:0145-2126
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Zini, Roberta; Guglielmelli, Paola; Pietra, Daniela; Rumi, Elisa; Rossi, Chiara; Rontauroli, Sebastiano; Genovese, Elena; Fanelli, Tiziana; Calabresi, Laura; Bianchi, Elisa; Salati, Simona; Cazzola, Mario; Tagliafico, Enrico; Vannucchi, Alessandro M.; Manfredini, Rossella (2017). CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles. BLOOD CANCER JOURNAL, vol. 7, pp. 638-638, ISSN:2044-5385
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Verstovsek, Srdan; Gotlib, Jason; Mesa, Ruben A.; Vannucchi, Alessandro M.; Kiladjian, Jean-Jacques; Cervantes, Francisco; Harrison, Claire N.; Paquette, Ronald; Sun, William; Naim, Ahmad; Langmuir, Peter; Dong, Tuochuan; Gopalakrishna, Prashanth; Gupta, Vikas (2017). Long-Term survival in patients treated with ruxolitinib for myelofibrosis: COMFORT-I and-II pooled analyses. JOURNAL OF HEMATOLOGY & ONCOLOGY, vol. 10, pp. 156-156, ISSN:1756-8722
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Salati, Simona; Prudente, Zelia; Genovese, Elena; Pennucci, Valentina; Rontauroli, Sebastiano; Bartalucci, Niccolo'; Mannarelli, Carmela; Ruberti, Samantha; Zini, Roberta; Rossi, Chiara; Bianchi, Elisa; Guglielmelli, Paola; Tagliafico, Enrico; Vannucchi, Alessandro M; Manfredini, Rossella (2017). Calreticulin affects hematopoietic stem/progenitor cell fate by impacting erythroid and megakaryocytic differentiation. STEM CELLS AND DEVELOPMENT, pp. 00-01, ISSN:1547-3287
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Tefferi, Ayalew; Lavu, Sravanthi; Mudireddy, Mythri; Lasho, Terra L; Finke, Christy M; Gangat, Naseema; Pardanani, Animesh; Hanson, Curtis A; Mannarelli, Carmela; Guglielmelli, Paola; Vannucchi, Alessandro M. (2017). JAK2 exon 12 mutated polycythemia vera: Mayo-Careggi MPN Alliance study of 33 consecutive cases and comparison with JAK2V617F mutated disease. AMERICAN JOURNAL OF HEMATOLOGY, pp. 00-01, ISSN:0361-8609
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Loscocco, G. G.; Vannucchi, M.; Paoli, C.; Franci, A.; Pieri, L.; Annunziato, F.; Massi, D.; Vannucchi, A. M (2017). Kaposi Sarcoma in a patient treated with Ruxolitinib. ANNALS OF ONCOLOGY, pp. 1-5, ISSN:0923-7534
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Mesa, Ruben A; Vannucchi, Alessandro M; Mead, Adam; Egyed, Miklos; Szoke, Anita; Suvorov, Aleksandr; Jakucs, Janos; Perkins, Andrew; Prasad, Ritam; Mayer, Jiri; Demeter, Judit; Ganly, Peter; Singer, Jack W; Zhou, Huafeng; Dean, James P; te Boekhorst, Peter A; Nangalia, Jyoti; Kiladjian, Jean-Jacques; Harrison, Claire N (2017). Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial. THE LANCET. HAEMATOLOGY, vol. 4, pp. e225-e236, ISSN:2352-3026
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Goel, Swati; Paoli, Chiara; Iurlo, Alessandra; Pereira, Arturo; Efficace, Fabio; Barbui, Tiziano; Tefferi, Ayalew; Vannucchi, Alessandro M.; Cervantes, Francisco (2017). Socioeconomic burden of participation in clinical trials in patients with myeloproliferative neoplasms. EUROPEAN JOURNAL OF HAEMATOLOGY, pp. 1-6, ISSN:0902-4441
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Coltro, Giacomo; Mannelli, Francesco; Guglielmelli, Paola; Pacilli, Annalisa; Bosi, Alberto; Vannucchi, Alessandro Maria (2017). A life-threatening ruxolitinib discontinuation syndrome. AMERICAN JOURNAL OF HEMATOLOGY, pp. 24775-24776, ISSN:0361-8609
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Guglielmelli, Paola; Pietra, Daniela; Pane, Fabrizio; Pancrazzi, Alessandro; Cazzola, Mario; Vannucchi, Alessandro M.; Tura, Sante; Barosi, Giovanni (2017). Recommendations for molecular testing in classical Ph1-neg myeloproliferative disorders–A consensus project of the Italian Society of Hematology. LEUKEMIA RESEARCH, vol. 58, pp. 63-72, ISSN:0145-2126
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Pacilli, Annalisa; Fanelli, Tiziana; Mannarelli, Carmela; Rotunno, Giada; Pancrazzi, Alessandro; Vannucchi, Alessandro Maria; Guglielmelli, Paola (2017). Clonal architecture of JAK2V617F mutated cells during treatment with ruxolitinib. HEMATOLOGICAL ONCOLOGY, pp. 1-3, ISSN:0278-0232
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Rontauroli, Sebastiano; Norfo, Ruggiero; Pennucci, Valentina; Zini, Roberta; Ruberti, Samantha; Bianchi, Elisa; Salati, Simona; Prudente, Zelia; Rossi, Chiara; Rosti, Vittorio; Guglielmelli, Paola; Barosi, Giovanni; Vannucchi, Alessandro; Tagliafico, Enrico; Manfredini, Rossella (2017). miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6. ONCOTARGET, vol. 8, pp. 21380-21397, ISSN:1949-2553
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Barbui, Tiziano; Carobbio, Alessandra; Ghirardi, Arianna; Masciulli, Arianna; Rambaldi, Alessandro; Vannucchi, Alessandro M. (2017). No correlation of intensity of phlebotomy regimen with risk of thrombosis in polycythemia vera: evidence from ECLAP and CYTO-PV clinical trials. HAEMATOLOGICA, pp. 1-9, ISSN:0390-6078
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Al-Ali, Haifa Kathrin; Vannucchi, Alessandro M. (2017). Managing patients with myelofibrosis and low platelet counts. ANNALS OF HEMATOLOGY, vol. 96, pp. 537-548, ISSN:0939-5555
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Koren-Michowitz, Maya; Lavi, Noa; Ellis, Martin H.; Vannucchi, Alessandro M.; Mesa, Ruben; Harrison, Claire N. (2017). Management of extreme thrombocytosis in myeloproliferative neoplasms: an international physician survey. ANNALS OF HEMATOLOGY, vol. 96, pp. 87-92, ISSN:0939-5555
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Barbui, Tiziano; Vannucchi, Alessandro M.; Carobbio, Alessandra; Rumi, Elisa; Finazzi, Guido; Gisslinger, Heinz; Ruggeri, Marco; Randi, Maria Luigia; Cazzola, Mario; Rambaldi, Alessandro; Gisslinger, Bettina; Pieri, Lisa; Thiele, Juergen; Pardanani, Animesh; Tefferi, Ayalew (2017). The effect of arterial hypertension on thrombosis in low-risk polycythemia vera. AMERICAN JOURNAL OF HEMATOLOGY, vol. 92, pp. E5-E6, ISSN:0361-8609
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Geyer, Holly L; Kosiorek, Heidi; Dueck, Amylou C.; Scherber, Robyn; Slot, Stefanie; Zweegman, Sonja; te Boekhorst, Peter A. W.; Senyak, Zhenya; Schouten, Harry C.; Sackmann, Federico; Fuentes, Ana Kerguelen; Hernández-Maraver, Dolores; Pahl, Heike L.; Griesshammer, Martin; Stegelmann, Frank; Döhner, Konstanze; Lehmann, Thomas; Bonatz, Karin; Reiter, Andreas; Boyer, Francoise; Etienne, Gabriel; Ianotto, Jean-Christophe; Ranta, Dana; Roy, Lydia; Cahn, Jean-Yves; Harrison, Claire N.; Radia, Deepti; Muxi, Pablo; Maldonado, Norman; Besses, Carlos; Cervantes, Francisco; Johansson, Peter L.; Barbui, Tiziano; Barosi, Giovanni; Vannucchi, Alessandro M.; Paoli, Chiara; Passamonti, Francesco; Andreasson, Bjorn; Ferrari, Maria L.; Rambaldi, Alessandro; Samuelsson, Jan; Cannon, Keith; Birgegard, Gunnar; Xiao, Zhijian; Xu, Zefeng; Zhang, Yue; Sun, Xiujuan; Xu, Junqing; Kiladjian, Jean-Jacques; Zhang, Peihong; Gale, Robert Peter; Mesa, Ruben A. (2017). Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: An analysis by the MPN QOL international working group. HAEMATOLOGICA, vol. 102, pp. 85-93, ISSN:0390-6078
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Scherber, Robyn Marie; Geyer, Holly Lynn; Dueck, Amylou C.; Kosiorek, Heidi E.; Finazzi, Guido; Cavazzina, Riccardo; Masciulli, Arianna; Scarano, Marco; Vannucchi, Alessandro M.; Mesa, Ruben A.; Barbui, Tiziano (2017). The potential role of hematocrit control on symptom burden among polycythemia vera patients: Insights from the CYTO-PV and MPN-SAF patient cohorts. LEUKEMIA & LYMPHOMA, vol. 58, pp. 1481-1487, ISSN:1042-8194
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Vannucchi, Alessandro M.; Harrison, Claire N (2017). Emerging treatments for classical myeloproliferative neoplasms. BLOOD, vol. 129, pp. 693-703, ISSN:0006-4971
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Passamonti, Francesco; Griesshammer, Martin; Palandri, Francesca; Egyed, Miklos; Benevolo, Giulia; Devos, Timothy; Callum, Jeannie; Vannucchi, Alessandro M; Sivgin, Serdar; Bensasson, Caroline; Khan, Mahmudul; Mounedji, Nadjat; Saydam, Guray (2017). Ruxolitinib for the treatment of inadequately controlled polycythaemia vera without splenomegaly (RESPONSE-2): a randomised, open-label, phase 3b study. THE LANCET ONCOLOGY, vol. 18, pp. 88-99, ISSN:1470-2045
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Vannucchi, Alessandro M (2017). From leeches to personalized medicine: Evolving concepts in the management of polycythemia vera. HAEMATOLOGICA, vol. 102, pp. 18-29, ISSN:0390-6078
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Verstovsek, Srdan; Harrison, Claire N.; Kiladjian, Jean-Jacques; Miller, Carole; Naim, Ahmad B.; Paranagama, Dilan C.; Habr, Dany; Vannucchi, Alessandro M. (2017). Markers of iron deficiency in patients with polycythemia vera receiving ruxolitinib or best available therapy. LEUKEMIA RESEARCH, vol. 56, pp. 52-59, ISSN:0145-2126
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Pieri, Lisa; Paoli, Chiara; Arena, Umberto; Marra, Fabio; Mori, Fabio; Zucchini, Mery; Colagrande, Stefano; Castellani, Alessandro; Masciulli, Arianna; Rosti, Vittorio; De Stefano, Valerio; Betti, Silvia; Finazzi, Guido; Ferrari, Maria Luisa; Rumi, Elisa; Ruggeri, Marco; Nichele, Ilaria; Guglielmelli, Paola; Fjerza, Rajmonda; Mannarelli, Carmela; Fanelli, Tiziana; Merli, Lucia; Corbizi Fattori, Giuditta; Massa, Margherita; Cimino, Giuseppe; Rambaldi, Alessandro; Barosi, Giovanni; Cazzola, Mario; Barbui, Tiziano; Vannucchi, Alessandro M. (2017). Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms. AMERICAN JOURNAL OF HEMATOLOGY, vol. 92, pp. 187-195, ISSN:0361-8609
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Passamonti, F; Mora, B.; Giorgino, T.; Guglielmelli, P.; Cazzola, M.; Maffioli, M.; Rambaldi, A.; Caramella, M.; Komrokji, R.; Gotlib, J.; Kiladjian, J.J.; Cervantes, F.; Devos, T.; Palandri, F.; de Stefano, V.; Ruggeri, M.; Silver, R.; Benevolo, G.; Albano, F.; Caramazza, D.; Rumi, E.; Merli, M.; Pietra, D.; Casalone, R.; Barbui, T.; Pieri, L.; Vannucchi, A.M. (2017). Driver mutations’ effect in secondary myelofibrosis: an international multicenter study based on 781 patients. LEUKEMIA, pp. 0-0, ISSN:0887-6924
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Bianchi, Elisa; Ruberti, Samantha; Rontauroli, Sebastiano; Guglielmelli, Paola; Salati, Simona; Rossi, Chiara; Zini, Roberta; Tagliafico, Enrico; Vannucchi, Alessandro Maria; Manfredini, Rossella (2017). Role of miR-34a-5p in hematopoietic progenitor cells proliferation and fate decision: Novel insights into the pathogenesis of primary myelofibrosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 18, pp. 145-167, ISSN:1661-6596
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Guglielmelli, Paola; Pacilli, Annalisa; Rotunno, Giada; Rumi, Elisa; Rosti, Vittorio; Delaini, Federica; Maffioli, Margherita; Fanelli, Tiziana; Pancrazzi, Alessandro; Pietra, Daniela; Salmoiraghi, Silvia; Mannarelli, Carmela; Franci, Annalisa; Paoli, Chiara; Rambaldi, Alessandro; Passamonti, Francesco; Barosi, Giovanni; Barbui, Tiziano; Cazzola, Mario; Vannucchi, Alessandro M (2017). Presentation and outcome of patients with 2016 WHO diagnosis of prefibrotic and overt primary myelofibrosis. BLOOD, vol. 129, pp. 0-0, ISSN:0006-4971
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Tefferi A.; Vannucchi A.M. (2017). Genetic Risk Assessment in Myeloproliferative Neoplasms. MAYO CLINIC PROCEEDINGS, vol. 92, pp. 1283-1290, ISSN:0025-6196
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Tefferi, A; Al Ali, H. K; Barosi, G; Devos, T; Gisslinger, H; Jiang, Q; Kiladjian, J. J; Mesa, R; Passamonti, F; Mcmullin, M. F; Ribrag, V; Schiller, G; Vannucchi, ALESSANDRO MARIA; Zhou, D; Reiser, D; Zhong, J; Gale, R. P. (2017). Erratum: A randomized study of pomalidomide vs placebo in persons with myeloproliferative neoplasm-associated myelofibrosis and RBC-transfusion dependence. LEUKEMIA, vol. 31, pp. 1252-1252, ISSN:0887-6924
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Vannucchi, Alessandro Maria; Verstovsek, Srdan; Guglielmelli, Paola; Griesshammer, Martin; Burn, Timothy C.; Naim, Ahmad; Paranagama, Dilan; Marker, Mahtab; Gadbaw, Brian; Kiladjian, Jean-Jacques (2017). Ruxolitinib reduces JAK2 p.V617F allele burden in patients with polycythemia vera enrolled in the RESPONSE study. ANNALS OF HEMATOLOGY, pp. 1-8, ISSN:0939-5555
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Barbui, Tiziano; Thiele, Juergen; Gisslinger, Heinz; Carobbio, Alessandra; Vannucchi, Alessandro M.; Tefferi, Ayalew (2017). Diagnostic impact of the 2016 revised who criteria for polycythemia vera. AMERICAN JOURNAL OF HEMATOLOGY, vol. 92, pp. 417-419, ISSN:0361-8609
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Mesa, Ruben; Vannucchi, Alessandro M.; Yacoub, Abdulraheem; Zachee, Pierre; Garg, Mamta; Lyons, Roger; Koschmieder, Steffen; Rinaldi, Ciro; Byrne, Jennifer; Hasan, Yasmin; Passamonti, Francesco; Verstovsek, Srdan; Hunter, Deborah; Jones, Mark M.; Zhen, Huiling; Habr, Dany; Martino, Bruno (2017). The efficacy and safety of continued hydroxycarbamide therapy versus switching to ruxolitinib in patients with polycythaemia vera: a randomized, double-blind, double-dummy, symptom study (RELIEF). BRITISH JOURNAL OF HAEMATOLOGY, vol. 176, pp. 76-85, ISSN:0007-1048
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Lussana, Federico; Carobbio, Alessandra; Salmoiraghi, Silvia; Guglielmelli, Paola; Vannucchi, Alessandro Maria; Bottazzi, Barbara; Leone, Roberto; Mantovani, Alberto; Barbui, Tiziano; Rambaldi, Alessandro (2017). Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera. JOURNAL OF HEMATOLOGY & ONCOLOGY, vol. 10, pp. 1-8, ISSN:1756-8722
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Marchetti, M; Barosi, G.; Cervantes, F.; Birgegård, G.; Griesshammer, M.; Harrison, C.; Hehlmann, R.; Kiladjian, J.-J.; Kröger, N.; Mcmullin, M.F.; Passamonti, F.; Vannucchi, A.; Barbui, T. (2017). Which patients with myelofibrosis should receive ruxolitinib therapy? ELN-SIE evidence-based recommendations. LEUKEMIA, vol. 31, pp. 882-888, ISSN:0887-6924
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Harrison, Claire N; Vannucchi, Alessandro M; Platzbecker, Uwe; Cervantes, Francisco; Gupta, Vikas; Lavie, David; Passamonti, Francesco; Winton, Elliott F; Dong, Hua; Kawashima, Jun; Maltzman, Julia D; Kiladjian, Jean-Jacques; Verstovsek, Srdan (2017). Momelotinib versus best available therapy in patients with myelofibrosis previously treated with ruxolitinib (SIMPLIFY 2): a randomised, open-label, phase 3 trial. THE LANCET. HAEMATOLOGY, pp. 00-01, ISSN:2352-3026
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Rotunno, Giada; Pacilli, Annalisa; Artusi, Valentina; Rumi, Elisa; Maffioli, Margherita; Delaini, Federica; Brogi, Giada; Fanelli, Tiziana; Pancrazzi, Alessandro; Pietra, Daniela; Bernardis, Isabella; Belotti, Clara; Pieri, Lisa; Sant'Antonio, Emanuela; Salmoiraghi, Silvia; Cilloni, Daniela; Rambaldi, Alessandro; Passamonti, Francesco; Barbui, Tiziano; Manfredini, Rossella; Cazzola, Mario; Tagliafico, Enrico; Vannucchi, Alessandro M; Guglielmelli, Paola (2016). Epidemiology and clinical relevance of mutations in post-polycythemia vera and post-essential thrombocythemia myelofibrosis. A study on 359 patients of the AGIMM group. AMERICAN JOURNAL OF HEMATOLOGY, vol. ....., pp. n/a-n/a, ISSN:0361-8609
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Geyer, Holly L.; Andreasson, Bjorn; Kosiorek, Heidi E.; Dueck, Amylou C.; Scherber, Robyn M.; Martin, Kari A.; Butler, Kristina A.; Harrison, Claire N.; Radia, Deepti H.; Cervantes, Francisco; Kiladjian, Jean-Jacques; Reiter, Andreas; Birgegard, Gunnar; Passamonti, Francesco; Senyak, Zhenya; Vannucchi, Alessandro M.; Paoli, Chiara; Xiao, Zhijian; Samuelsson, Jan; Mesa, Ruben A (2016). The role of sexuality symptoms in myeloproliferative neoplasm symptom burden and quality of life: An analysis by the MPN QOL International Study Group. CANCER, vol. 122, pp. 1888-1896, ISSN:0008-543X
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Verstovsek, Srdan; Vannucchi, Alessandro M.; Griesshammer, Martin; Masszi, Tamas; Durrant, Simon; Passamonti, Francesco; Harrison, Claire N.; Pane, Fabrizio; Zachee, Pierre; Kirito, Keita; Besses, Carlos; Hino, Masayuki; Moiraghi, Beatriz; Miller, Carole B.; Cazzola, Mario; Rosti, Vittorio; Blau, Igor; Mesa, Ruben; Jones, Mark M.; Zhen, Huiling; Li, Jingjin; Francillard, Nathalie; Habr, Dany; Kiladjian, Jean-Jacques (2016). Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial. HAEMATOLOGICA, vol. 101, pp. 821-829, ISSN:0390-6078
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Barbui, Tiziano; Thiele, Jürgen; Vannucchi, Alessandro M.; Tefferi, Ayalew (2016). Myeloproliferative neoplasms: Morphology and clinical practice. AMERICAN JOURNAL OF HEMATOLOGY, vol. 91, pp. 430-433, ISSN:0361-8609
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Harrison, Claire N.; Vannucchi, Alessandro M. (2016). Closing the gap: Genetic landscape of MPN. BLOOD, vol. 127, pp. 276-278, ISSN:0006-4971
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Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; De Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; De Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Sall Es, Gilles; Schuringa, Jan Jacob; André, Marc; Andre-Schmutz, Isabelle; Bacigalupo, Andrea; Bochud, Pierre-Yves; Den Boer, Monique; Bonini, Chiara; Camaschella, Clara; Cant, Andrew; Cappellini, Maria Domenica; Cazzola, Mario; Celso, Cristina Lo; Dimopoulos, Meletios; Douay, Luc; Dzierzak, Elaine; Einsele, Hermann; Ferreri, Andrés; De Franceschi, Lucia; Gaulard, Philippe; Gottgens, Berthold; Greinacher, Andreas; Gresele, Paolo; Gribben, John; De Haan, Gerald; Hansen, John-Bjarne; Hochhaus, Andreas; Kadir, Rezan; Kaveri, Srini; Kouskoff, Valerie; Kühne, Thomas; Kyrle, Paul; Ljungman, Per; Maschmeyer, Georg; Méndez-Ferrer, Simón; Milsom, Michael; Mummery, Christine; Ossenkoppele, Gert; Pecci, Alessandro; Peyvandi, Flora; Philipsen, Sjaak; Reitsma, Pieter; Ribera, José Maria; Risitano, Antonio; Rivella, Stefano; Ruf, Wolfram; Schroeder, Timm; Scully, Marie; Socie, Gerard; Staal, Frank; Stanworth, Simon; Stauder, Reinhard; Stilgenbauer, Stephan; Tamary, Hannah; Theilgaard-Mönch, Kim; Thein, Swee Lay; Tilly, Hervé; Trneny, Marek; Vainchenker, William; Vannucchi, Alessandro Maria; Viscoli, Claudio; Vrielink, Hans; Zaaijer, Hans; Zanella, Alberto; Zolla, Lello; Zwaginga, Jaap Jan; Martinez, Patricia Aguilar; Van Den Akker, Emile; Allard, Shubha; Anagnou, Nicholas; Andolfo, Immacolata; Andrau, Jean-Christophe; Angelucci, Emanuele; Anstee, David; Aurer, Igor; Avet-Loiseau, Hervé; Aydinok, Yesim; Bakchoul, Tamam; Balduini, Alessandra; Barcellini, Wilma; Baruch, Dominique; Baruchel, André; Bayry, Jagadeesh; Bento, Celeste; Van Den Berg, Anke; Bernardi, Rosa; Bianchi, Paola; Bigas, Anna; Biondi, Andrea; Bohonek, Milos; Bonnet, Dominique; Borchmann, Peter; Borregaard, Niels; Brækkan, Sigrid; Van Den Brink, Marcel; Brodin, Ellen; Bullinger, Lars; Buske, Christian; Butzeck, Barbara; Cammenga, Jörg; Campo, Elias; Carbone, Antonino; Cervantes, Francisco; Cesaro, Simone; Charbord, Pierre; Claas, Frans; Cohen, Hannah; Conard, Jacqueline; Coppo, Paul; Vives Corron, Joan-Lluis; Da Costa, Lydie; Davi, Frederic; Delwel, Ruud; Dianzani, Irma; Domanović, Dragoslav; Donnelly, Peter; Drnovšek, Tadeja Dovč; Dreyling, Martin; Du, Ming-Qing; Dufour, Carlo; Durand, Charles; Efremov, Dimitar; Eleftheriou, Androulla; Elion, Jacques; Emonts, Marieke; Engelhardt, Monika; Ezine, Sophie; Falkenburg, Fred; Favier, Remi; Federico, Massimo; Fenaux, Pierre; Fitzgibbon, Jude; Flygare, Johan; Foà, Robin; Forrester, Lesley; Galacteros, Frederic; Garagiola, Isabella; Gardiner, Chris; Garraud, Olivier; Van Geet, Christel; Geiger, Hartmut; Geissler, Jan; Germing, Ulrich; Ghevaert, Cedric; Girelli, Domenico; Godeau, Bertrand; Gökbuget, Nicola; Goldschmidt, Hartmut; Goodeve, Anne; Graf, Thomas; Graziadei, Giovanna; Griesshammer, Martin; Gruel, Yves; Guilhot, Francois; Von Gunten, Stephan; Gyssens, Inge; Halter, Jörg; Harrison, Claire; Harteveld, Cornelis; Hellström-Lindberg, Eva; Hermine, Olivier; Higgs, Douglas; Hillmen, Peter; Hirsch, Hans; Hoskin, Peter; Huls, Gerwin; Inati, Adlette; Johnson, Peter; Kattamis, Antonis; Kiefel, Volker; Kleanthous, Marina; Klump, Hannes; Krause, Daniela; Hovinga, Johanna Kremer; Lacaud, Georges; Lacroix-Desmazes, Sébastien; Landman-Parker, Judith; Legouill, Steven; Lenz, Georg; Von Lilienfeld-Toal, Marie; Von Lindern, Marieke; Lopez-Guillermo, Armando; Lopriore, Enrico; Lozano, Miguel; Macintyre, Elizabeth; Makris, Michael; Mannhalter, Christine; Martens, Joost; Mathas, Stephan; Matzdorff, Axel; Medvinsky, Alexander; Menendez, Pablo; Migliaccio, Anna Rita; Miharada, Kenichi; Mikulska, Malgorzata; Minard, Véronique; Montalbán, Carlos; De Montalembert, Mariane; Montserrat, Emili; Morange, Pierre-Emmanuel; Mountford, Joanne; Muckenthaler, Ma (2016). The european hematology association roadmap for european hematology research: A consensus document. HAEMATOLOGICA, vol. 101, pp. 115-208, ISSN:0390-6078
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Al-Ali, Haifa Kathrin; Griesshammer, Martin; le Coutre, Philipp; Waller, Cornelius F.; Liberati, Anna Marina; Schafhausen, Philippe; Tavares, Renato; Giraldo, Pilar; Foltz, Lynda; Raanani, Pia; Gupta, Vikas; Tannir, Bayane; Ronco, Julian Perez; Ghosh, Jagannath; Martino, Bruno; Vannucchi, Alessandro M. (2016). Safety and efficacy of ruxolitinib in an open-label, multicenter, single-arm phase 3b expanded-access study in patients with myelofibrosis: A snapshot of 1144 patients in the JUMP trial. HAEMATOLOGICA, vol. 101, pp. 1065-1073, ISSN:0390-6078
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Harrison, C.N; Vannucchi, A.M.; Kiladjian, J.-J.; Al-Ali, H.K.; Gisslinger, H.; Knoops, L.; Cervantes, F.; Jones, M.M.; Sun, K.; Mcquitty, M.; Stalbovskaya, V.; Gopalakrishna, P.; Barbui, T. (2016). Long-term findings from COMFORT-II, a phase 3 study of ruxolitinib vs best available therapy for myelofibrosis. LEUKEMIA, vol. 30, pp. 1701-1707, ISSN:0887-6924
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De Stefano, V.; Ruggeri, M.; Cervantes, F.; Alvarez-Larrán, A.; Iurlo, A.; Randi, M.L.; Elli, E.; Finazzi, M.C.; Finazzi, G.; Zetterberg, E.; Vianelli, N.; Gaidano, G.; Rossi, E.; Betti, S.; Nichele, I.; Cattaneo, D.; Palova, M.; Ellis, M.H.; Cacciola, R.; Tieghi, A.; Hernandez-Boluda, J.C.; Pungolino, E.; Specchia, G.; Rapezzi, D.; Forcina, A.; Musolino, C.; Carobbio, A.; Griesshammer, M.; Sant'Antonio, E.; Vannucchi, A.M.; Barbui, T (2016). High rate of recurrent venous thromboembolism in patients with myeloproliferative neoplasms and effect of prophylaxis with Vitamin K antagonists. LEUKEMIA, vol. 30, pp. 2032-2038, ISSN:0887-6924
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Pieri, Lisa; Vannucchi, Alessandro M. (2016). Improving prognostic tools in systemic mastocytosis: Insights from mutations. AMERICAN JOURNAL OF HEMATOLOGY, vol. 91, pp. 867-868, ISSN:0361-8609
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Barbui, T; Thiele, J.; Gisslinger, H.; Finazzi, G.; Vannucchi, A.M.; Tefferi, A. (2016). The 2016 revision of WHO classification of myeloproliferative neoplasms: Clinical and molecular advances. BLOOD REVIEWS, vol. 30, pp. 453-459, ISSN:0268-960X
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Balliu, Manjola; Cellai, Cristina; Lulli, Matteo; Laurenzana, Anna; Torre, Eugenio; Vannucchi, Alessandro Maria; Paoletti, Francesco (2016). HDAC1 controls CIP2A transcription in human colorectal cancer cells. ONCOTARGET, vol. 7, pp. 25862-25871, ISSN:1949-2553
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Loscocco, Giuseppe Gaetano; Mannarelli, Carmela; Pacilli, Annalisa; Fanelli, Tiziana; Rotunno, Giada; Gesullo, Francesca; Corbizi-Fattori, Giuditta; Vannucchi, Alessandro Maria; Guglielmelli, Paola (2016). Germline transmission of LNKE208Q variant in a family with myeloproliferative neoplasms. AMERICAN JOURNAL OF HEMATOLOGY, vol. 91, pp. E356-E356, ISSN:0361-8609
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Guglielmelli, Paola; Rotunno, Giada; Pacilli, Annalisa; Rumi, Elisa; Rosti, Vittorio; Delaini, Federica; Maffioli, Margherita; Fanelli, Tiziana; Pancrazzi, Alessandro; Pieri, Lisa; Fjerza, Rajmonda; Pietra, Daniela; Cilloni, Daniela; Sant'Antonio, Emanuela; Salmoiraghi, Silvia; Passamonti, Francesco; Rambaldi, Alessandro; Barosi, Giovanni; Barbui, Tiziano; Cazzola, Mario; Vannucchi, Alessandro M. (2016). Prognostic impact of bone marrow fibrosis in primary myelofibrosis. A study of the AGIMM group on 490 patients. AMERICAN JOURNAL OF HEMATOLOGY, vol. 91, pp. 918-922, ISSN:0361-8609
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De Stefano, V.; Vannucchi, A.M.; Ruggeri, M.; Cervantes, F.; Alvarez-Larrán, A.; Iurlo, A.; Randi, M.L.; Pieri, L.; Rossi, E.; Guglielmelli, P.; Betti, S.; Elli, E.; Finazzi, M.C.; Finazzi, G.; Zetterberg, E.; Vianelli, N.; Gaidano, G.; Nichele, I.; Cattaneo, D.; Palova, M.; Ellis, M.H.; Cacciola, E.; Tieghi, A.; Hernandez-Boluda, J.C.; Pungolino, E.; Specchia, G.; Rapezzi, D.; Forcina, A.; Musolino, C.; Carobbio, A.; Griesshammer, M.; Barbui, T (2016). Splanchnic vein thrombosis in myeloproliferative neoplasms: Risk factors for recurrences in a cohort of 181 patients. BLOOD CANCER JOURNAL, vol. 6, pp. e493-e500, ISSN:2044-5385
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Pieri, Lisa; Rotunno, Giada; Gesullo, Francesca; Fanelli, Tiziana; Corbizi Fattori, Giuditta; Pacilli, Annalisa; Scarfì, Federica; Iorno, Maria Loredana; Almerigogna, Fabio; Salerno, Roberto; Guglielmelli, Paola; Zanotti, Roberta; Vannucchi, Alessandro M. (2016). Prognotic Impact of Mutations in Systemic Mastocytosis. BLOOD, vol. 128, pp. 1953-1953, ISSN:0006-4971
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Tefferi, Ayalew; Lasho, Terra L; Guglielmelli, Paola; Finke, Christy M; Rotunno, Giada; Elala, Yoseph; Pacilli, Annalisa; Hanson, Curtis A; Pancrazzi, Alessandro; Ketterling, Rhett P; Mannarelli, Carmela; Barraco, Daniela; Fanelli, Tiziana; Pardanani, Animesh; Gangat, Naseema; Vannucchi, Alessandro M (2016). Targeted deep sequencing in polycythemia vera and essential thrombocythemia. BLOOD ADVANCES, vol. 1, pp. 21-30, ISSN:2473-9529
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Shimizu, Takafumi; Kubovcakova, Lucia; Nienhold, Ronny; Zmajkovic, Jakub; Meyer, Sara C.; Hao-Shen, Hui; Geier, Florian; Dirnhofer, Stephan; Guglielmelli, Paola; Vannucchi, Alessandro M.; Milosevic Feenstra, Jelena D.; Kralovics, Robert; Orkin, Stuart H.; Skoda, Radek C (2016). Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis. JOURNAL OF EXPERIMENTAL MEDICINE, vol. 213, pp. 1479-1496, ISSN:0022-1007
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Guglielmelli, Paola; Vannucchi, Alessandro M. (2016). The prognostic impact of bone marrow fibrosis in primary myelofibrosis. AMERICAN JOURNAL OF HEMATOLOGY, vol. 91, pp. E454-E455, ISSN:0361-8609
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Calura, E; Pizzini, S; Bisognin, A; Coppe, A; Sales, G; Gaffo, E; Fanelli, T; Mannarelli, C; Zini, R; Norfo, R; Pennucci, V; Manfredini, R; Romualdi, C; Guglielmelli, P; Vannucchi, A M; Bortoluzzi, S (2016). A data-driven network model of primary myelofibrosis: transcriptional and post-transcriptional alterations in CD34+ cells. BLOOD CANCER JOURNAL, vol. 6, pp. e439-e448, ISSN:2044-5385
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De Luca, Francesca; Rotunno, Giada; Salvianti, Francesca; Galardi, Francesca; Pestrin, Marta; Gabellini, Stefano; Simi, Lisa; Mancini, Irene; Vannucchi, Alessandro Maria; Pazzagli, Mario; Di Leo, Angelo; Pinzani, Pamela (2016). Mutational analysis of single circulating tumor cells by next generation sequencing in metastatic breast cancer. ONCOTARGET, vol. 7, pp. 26107-26119, ISSN:1949-2553
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Calistri, Linda; Pieri, Lisa; Santi, Raffaella; Nardi, Cosimo; Vannucchi, Alessandro Maria; Colagrande, Stefano (2016). MR imaging in non-hepatosplenic extramedullary hematopoiesis in primary myelofibrosis. AMERICAN JOURNAL OF HEMATOLOGY, pp. 0-0, ISSN:1096-8652
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Emmi, Giacomo; Silvestri, Elena; Marconi, Roberto; Carrai, Valentina; Fanelli, Tiziana; Zucchini, Patrizia; Marasca, Roberto; Vannucchi, Alessandro Maria; Emmi, Lorenzo; Prisco, Domenico; Vaglio, Augusto (2015). First report of FIP1L1-PDGFR alpha-positive eosinophilic granulomatosis with polyangiitis. RHEUMATOLOGY, vol. 54, pp. 1751-1753, ISSN:1462-0324
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L. Pieri;P. Guglielmelli;A. M. Vannucchi (2015). Ruxolitinib-induced reversal of alopecia universalis in a patient with essential thrombocythemia.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 90, pp. 82-83, ISSN:0361-8609
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Vannucchi, Alessandro M; Bartalucci, Niccolo; Pieri, Lisa; Guglielmelli, Paola (2015). Rationale for combination therapies in myelofibrosis. In: alessandro maria vannucchi, Niccolò bartalucci, Lisa Pieri, paola guglielmelli,. Novel Insights into Myelofibrosis Pathophysiology and Treatment, pp. 136-150 Future Medicine Ltd., ISBN:9781780845494.
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Guglielmelli, P; Rotunno, G; Brogi, G; Pacilli, A; Bogani, C; Mannarelli, C; Pancrazzi, A; Fjerza, R; Pieri, L; Rumi, E; Pietra, D; Salmoiraghi, S; Provenzano, A; Giunti, L; Giglio, S; Maffioli, M; Bosi, A; Rambaldi, A; Barbui, T; Passamonti, F; Cazzola, M; Vannucchi, Am (2014). Calreticulin Mutation Is Associated with Milder Disease in Patients with Post Essential Thrombocythemia Myelofibrosis (PET-MF) Compared with JAK2V617F Mutation: A Study from the AGIMM Group. BLOOD, vol. 124, pp. 3179-3179, ISSN:0006-4971
Pennucci V;Zini R;Norfo R;Guglielmelli P;Bianchi E;Salati S;Sacchi G;Prudente Z;Tenedini E;Ruberti S;Paoli C;Fanelli T;Mannarelli C;Tagliafico E;Ferrari S;Vannucchi AM;Manfredini R. (2014). Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34+ cells from patients with primary myelofibrosis and their clinical correlations.. LEUKEMIA & LYMPHOMA, pp. 1-5, ISSN:1042-8194
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Guglielmelli P;Bartalucci N;Rotunno G;Vannucchi AM (2014). Calreticulin: a new horizon for the testing and treatment of myeloproliferative neoplasms.. EXPERT REVIEW OF HEMATOLOGY, vol. 7, pp. 423-425, ISSN:1747-4086
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Rotunno G;Guglielmelli P;Biamonte F;Rumi E;Cazzola M;Vannucchi AM (2014). Mutational analysis of BCORL1 in the leukemic transformation of chronic myeloproliferative neoplasms.. ANNALS OF HEMATOLOGY, vol. 93, pp. 523-524, ISSN:0939-5555
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G. Finazzi;A. Carobbio;P. Guglielmelli;C. Cavalloni;S. Salmoiraghi;A. M. Vannucchi;M. Cazzola;F. Passamonti;A. Rambaldi;T. Barbui (2014). Calreticulin mutation does not modify the IPSET score for predicting the risk of thrombosis among 1150 patients with essential thrombocythemia.. BLOOD, vol. 124, pp. 2611-2612, ISSN:0006-4971
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Norfo R;Zini R;Pennucci V;Bianchi E;Salati S;Guglielmelli P;Bogani C;Fanelli T;Mannarelli C;Rosti V;Pietra D;Salmoiraghi S;Bisognin A;Ruberti S;Rontauroli S;Sacchi G;Prudente Z;Barosi G;Cazzola M;Rambaldi A;Bortoluzzi S;Ferrari S;Tagliafico E;Vannucchi AM;Manfredini R (2014). miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells unveils the role of miR-155/JARID2 axis in abnormal megakaryopoiesis.. BLOOD, vol. 124, pp. E21-E32, ISSN:0006-4971
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R. Castelli;M. Cugno;U. Gianelli;A. Pancrazzi;A. M. Vannucchi (2014). Neutrophilic progression in a case of polycytemia vera mimicking chronic neutrophilic leukemia: Clinical and molecular characterization.. PATHOLOGY RESEARCH AND PRACTICE, vol. 14, pp. 287-288, ISSN:0344-0338
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Rumi E, Pietra D, Pascutto C, Guglielmelli P, Martínez-Trillos A, Casetti I, Colomer D, Pieri L, Pratcorona M, Rotunno G, Sant'Antonio E, Bellini M, Cavalloni C, Mannarelli C, Milanesi C, Boveri E, Ferretti V, Astori C, Rosti V, Cervantes F, Barosi G, Vannucchi AM, Cazzola M;Bisognin, A; Bogani, C; Bortoluzzi, S; Bosi, A (2014). Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis.. BLOOD, pp. 1062-1069, ISSN:0006-4971
Barosi G;Vannucchi AM;De Stefano V;Pane F;Passamonti F;Rambaldi A;Saglio G;Barbui T;Tura S (2014). Identifying and addressing unmet clinical needs in Ph-neg classical myeloproliferative neoplasms: a consensus-based SIE, SIES, GITMO position paper.. LEUKEMIA RESEARCH, vol. 38, pp. 155-160, ISSN:0145-2126
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Barbui T;Thiele J;Carobbio A;Gisslinger H;Finazzi G;Rumi E;Luigia Randi M;Vannucchi AM;Gisslinger B;Müllauer L;Ruggeri M;Rambaldi A;Tefferi A (2014). Masked polycythemia vera diagnosed according to WHO and BCSH classification.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 89, pp. 199-202, ISSN:0361-8609
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Barbui T;Thiele J;Vannucchi AM;Tefferi A (2014). Rethinking the diagnostic criteria of polycythemia vera.. LEUKEMIA, vol. 28, pp. 1191-1195, ISSN:0887-6924
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Rondelli D;Goldberg JD;Isola L;Price LS;Shore TB;Boyer M;Bacigalupo A;Rambaldi A;Scarano M;Klisovic RB;Gupta V;Andreasson B;Mascarenhas J;Wetzler M;Vannucchi AM;Prchal JT;Najfeld V;Orazi A;Weinberg RS;Miller C;Barosi G;Silverman LR;Prosperini G;Marchioli R;Hoffman R (2014). MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis.. BLOOD, vol. 124, pp. 1183-1191, ISSN:0006-4971
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Verstovsek S;Passamonti F;Rambaldi A;Barosi G;Rosen PJ;Rumi E;Gattoni E;Pieri L;Guglielmelli P;Elena C;He S;Contel N;Mookerjee B;Sandor V;Cazzola M;Kantarjian HM;Barbui T;Vannucchi AM (2014). A phase 2 study of ruxolitinib, an oral JAK1 and JAK2 Inhibitor, in patients with advanced polycythemia vera who are refractory or intolerant to hydroxyurea.. CANCER, vol. 120, pp. 513-520, ISSN:0008-543X
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Tefferi A;Wassie EA;Guglielmelli P;Gangat N;Belachew AA;Lasho TL;Finke C;Ketterling RP;Hanson CA;Pardanani A;Wolanskyj AP;Maffioli M;Casalone R;Pacilli A;Vannucchi AM;Passamonti F (2014). Type 1 versus Type 2 calreticulin mutations in essential thrombocythemia: A collaborative study of 1027 patients.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 89, pp. e121-e124, ISSN:0361-8609
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Tefferi A;Guglielmelli P;Lasho TL;Rotunno G;Finke C;Mannarelli C;Belachew AA;Pancrazzi A;Wassie EA;Ketterling RP;Hanson CA;Pardanani A;Vannucchi AM (2014). CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: an international study of 570 patients.. LEUKEMIA, vol. 28, pp. 1494-1500, ISSN:0887-6924
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Rotunno G;Mannarelli C;Guglielmelli P;Pacilli A;Pancrazzi A;Pieri L;Fanelli T;Bosi A;Vannucchi AM. (2014). Impact of calreticulin mutations on clinical and hematological phenotype and outcome in essential thrombocythemia.. BLOOD, vol. 123, pp. 1552-1555, ISSN:0006-4971
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Randi ML;Bertozzi I;Rumi E;Elena C;Finazzi G;Vianelli N;Polverelli N;Ruggeri M;Vannucchi AM;Antonioli E;Lussana F;Tieghi A;Iurlo A;Elli E;Ruella M;Fabris F;Cazzola M;Barbui T (2014). Pregnancy complications predict thrombotic events in young women with essential thrombocythemia.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 89, pp. 306-309, ISSN:0361-8609
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Tenedini E;Bernardis I;Artusi V;Artuso L;Roncaglia E;Guglielmelli P;Pieri L;Bogani C;Biamonte F;Rotunno G;Mannarelli C;Bianchi E;Pancrazzi A;Fanelli T;Malagoli Tagliazucchi G;Ferrari S;Manfredini R;Vannucchi AM;Tagliafico E. (2014). Targeted cancer exome sequencing reveals recurrent mutations in myeloproliferative neoplasms.. LEUKEMIA, vol. 28, pp. 1052-1059, ISSN:0887-6924
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Guglielmelli P;Biamonte F;Rotunno G;Artusi V;Artuso L;Bernardis I;Tenedini E;Pieri L;Paoli C;Mannarelli C;Fjerza R;Rumi E;Stalbovskaya V;Squires M;Cazzola M;Manfredini R;Harrison C;Tagliafico E;Vannucchi AM. (2014). Impact of mutational status on outcomes in myelofibrosis patients treated with ruxolitinib in the COMFORT-II study.. BLOOD, vol. 123, pp. 2157-2160, ISSN:0006-4971
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F. Lussana;A. Carobbio;M. L. Randi;C. Elena;E. Rumi;G. Finazzi;I. Bertozzi;L. Pieri;M. Ruggeri;F. Palandri;N. Polverelli;E. Elli;A. Tieghi;A. Iurlo;M. Ruella;M. Cazzola;A. Rambaldi;A. M. Vannucchi;T. Barbui (2014). A lower intensity of treatment may underlie the increased risk of thrombosis in young patients with masked polycythaemia vera.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 167, pp. 541-546, ISSN:0007-1048
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Passamonti F;Maffioli M;Cervantes F;Vannucchi AM;Morra E;Barbui T;Caramazza D;Pieri L;Rumi E;Gisslinger H;Knoops L;Kiladjian JJ;Mora B;Hollaender N;Pascutto C;Harrison C;Cazzola M (2014). Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts.. BLOOD, vol. 123, pp. 1833-1835, ISSN:0006-4971
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Mughal TI;Vannucchi AM;Soverini S;Bazeos A;Tibes R;Saglio G;Abdel-Wahab O;Pardanani A;Hehlmann R;Barbui T;Van Etten R;Tefferi A;Goldman JM (2014). Current pre-clinical and clinical advances in the BCR-ABL1-positive and -negative chronic myeloproliferative neoplasms.. HAEMATOLOGICA, vol. 99, pp. 797-801, ISSN:0390-6078
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Barbui T;Thiele J;Gisslinger H;Finazzi G;Carobbio A;Rumi E;Luigia Randi M;Betozzi I;Vannucchi AM;Pieri L;Carrai V;Gisslinger B;Müllauer L;Ruggeri M;Rambaldi A;Tefferi A (2014). Masked polycythemia vera (mPV): results of an international study.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 89, pp. 52-54, ISSN:0361-8609
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Martinelli I;De Stefano V;Carobbio A;Randi ML;Santarossa C;Rambaldi A;Finazzi MC;Cervantes F;Arellano-Rodrigo E;Rupoli S;Canafoglia L;Tieghi A;Facchini L;Betti S;Vannucchi AM;Pieri L;Cacciola R;Cacciola E;Cortelezzi A;Iurlo A;Pogliani EM;Elli EM;Spadea A;Barbui T (2014). Cerebral vein thrombosis in patients with Philadelphia-negative myeloproliferative neoplasms An European Leukemia Net study.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 89, pp. E200-E205, ISSN:0361-8609
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A. M. Vannucchi (2014). How I treat polycythemia vera.. BLOOD, vol. 124, pp. 3212-3220, ISSN:0006-4971
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T. Barbui;A. Carobbio;E. Rumi;G. Finazzi;H. Gisslinger;F. Rodeghiero;M. L. Randi;A. Rambaldi;B. Gisslinger;L. Pieri;I. Bertozzi;I. Casetti;A. Pardanani;F. Passamonti;A. M. Vannucchi;A. Tefferi (2014). In contemporary patients with polycythemia vera, rates of thrombosis and risk factors delineate a new clinical epidemiology.. BLOOD, vol. 124, pp. 3021-3023, ISSN:0006-4971
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M. H. Ellis;N. Lavi;A. Vannucchi;C. Harrison (2014). Treatment of thromboembolic events coincident with the diagnosis of myeloproliferative neoplasms: a physician survey.. THROMBOSIS RESEARCH, vol. 134, pp. 251-254, ISSN:0049-3848
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Barbui T;Thiele J;Carobbio A;Guglielmelli P;Rambaldi A;Vannucchi AM;Tefferi A (2014). Discriminating between essential thrombocythemia and masked polycythemia vera in JAK2 mutated patients.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 89, pp. 588-590, ISSN:0361-8609
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Geyer HL;Scherber RM;Dueck AC;Kiladjian JJ;Xiao Z;Slot S;Zweegman S;Sackmann F;Fuentes AK;Hernández-Maraver D;Döhner K;Harrison CN;Radia D;Muxi P;Besses C;Cervantes F;Johansson PL;Andreasson B;Rambaldi A;Barbui T;Vannucchi AM;Passamonti F;Samuelsson J;Birgegard G;Mesa RA (2014). Distinct clustering of symptomatic burden among myeloproliferative neoplasm patients: retrospective assessment in 1470 patients.. BLOOD, vol. 123, pp. 3803-3810, ISSN:0006-4971
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Francesco Epifani; Paola Guglielmelli; Idalba Loiacono; Andrea Epifani; Lisa Pieri; Alessandro Maria Vannucchi (2014). MPN Score.
Vannucchi, A.M.; Rotunno, G.; Bartalucci, N.; Raugei, G.; Carrai, V.; Balliu, M.; Mannarelli, C.; Pacilli, A.; Calabresi, L.; Fjerza, R.; Pieri, L.; Bosi, A.; Manfredini, R.; Guglielmelli, P. (2014). Calreticulin mutation-specific immunostaining in myeloproliferative neoplasms: Pathogenetic insight and diagnostic value. LEUKEMIA, vol. 28, pp. 1811-1818, ISSN:0887-6924
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T. Barbui;J. Thiele;A. Carobbio;A. M. Vannucchi;A. Tefferi (2014). The rate of transformation from JAK2-mutated ET to PV is influenced by an accurate WHO-defined clinico-morphological diagnosis.. LEUKEMIA, vol. 29, pp. 992-993, ISSN:0887-6924
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Marchioli R; Specchia G; Finazzi G; Cacciola R; Cavazzina R; Cilloni D; De Stefano V; Elli E; Iurlo A; Latagliata R; Lunghi F; Marfisi RM; Musto P; Masciulli A; Musolino C; Cascavilla N; Quarta G; Randi ML; Rapezi Davide; Ruggeri M; Rumi E; Scortechini AR; Santini S; Scarano M; Siragusa S; Spadea A; Tieghi A; Angelucci E; Visani G; Vannucchi AM; Barbui T; CYTO-PV Collaborative Group (2013). Cardiovascular events and intensity of treatment in polycythemia vera.. THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 368, pp. 22-33, ISSN:0028-4793
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Barosi G;Mesa R;Finazzi G;Harrison C;Kiladjian JJ;Lengfelder E;McMullin MF;Passamonti F;Vannucchi AM;Besses C;Gisslinger H;Samuelsson J;Verstovsek S;Hoffman R;Pardanani A;Cervantes F;Tefferi A;Barbui T (2013). Revised response criteria for polycythemia vera and essential thrombocythemia: an ELN and IWG-MRT consensus project.. BLOOD, vol. 121, pp. 4778-4781, ISSN:0006-4971
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Susini MC;Guglielmelli P;Spolverini A;Biamonte F;Mannarelli C;Barosi G;Zoi K;Reiter A;Duncombe A;Cervantes F;Cazzola M;Cross N;Vannucchi AM. (2013). The ERCC2 Gln/Gln polymorphism at codon 751 is not associated with leukaemic transformation in primary myelofibrosis.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 162, pp. 424-427, ISSN:0007-1048
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Tefferi A;Cervantes F;Mesa R;Passamonti F;Verstovsek S;Vannucchi AM;Gotlib J;Dupriez B;Pardanani A;Harrison C;Hoffman R;Gisslinger H;Kröger N;Thiele J;Barbui T;Barosi G (2013). Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report.. BLOOD, vol. 122, pp. 1395-1398, ISSN:0006-4971
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Poletto V;Villani L;Catarsi P;Campanelli R;Massa M;Vannucchi AM;Rosti V;Barosi G (2013). No association between the XPD Lys751Gln (rs13181) polymorphism and disease phenotype or leukemic transformation in primary myelofibrosis.. HAEMATOLOGICA, vol. 98, pp. e83-e84, ISSN:0390-6078
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Klampfl T;Milosevic JD;Puda A;Schönegger A;Bagienski K;Berg T;Harutyunyan AS;Gisslinger B;Rumi E;Malcovati L;Pietra D;Elena C;Della Porta MG;Pieri L;Guglielmelli P;Bock C;Doubek M;Dvorakova D;Suvajdzic N;Tomin D;Tosic N;Racil Z;Steurer M;Pavlovic S;Vannucchi AM;Cazzola M;Gisslinger H;Kralovics R (2013). Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.. PLOS ONE, vol. 8, pp. e77819-e77826, ISSN:1932-6203
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Bartalucci N;Bogani C;Vannucchi AM (2013). Preclinical models for drug selection in myeloproliferative neoplasms.. CURRENT HEMATOLOGIC MALIGNANCY REPORTS, vol. 8, pp. 317-324, ISSN:1558-8211
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Nangalia J;Massie CE;Baxter EJ;Nice FL;Gundem G;Wedge DC;Avezov E;Li J;Kollmann K;Kent DG;Aziz A;Godfrey AL;Hinton J;Martincorena I;Van Loo P;Jones AV;Guglielmelli P;Tarpey P;Harding HP;Fitzpatrick JD;Goudie CT;Ortmann CA;Loughran SJ;Raine K;Jones DR;Butler AP;Teague JW;O'Meara S;McLaren S;Bianchi M;Silber Y;Dimitropoulou D;Bloxham D;Mudie L;Maddison M;Robinson B;Keohane C;Maclean C;Hill K;Orchard K;Tauro S;Du MQ;Greaves M;Bowen D;Huntly BJ;Harrison CN;Cross NC;Ron D;Vannucchi AM;Papaemmanuil E;Campbell PJ;Green AR (2013). Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.. THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 369, pp. 2391-2405, ISSN:0028-4793
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Jovanovic JV;Ivey A;Vannucchi AM;Lippert E;Oppliger Leibundgut E;Cassinat B;Pallisgaard N;Maroc N;Hermouet S;Nickless G;Guglielmelli P;van der Reijden BA;Jansen JH;Alpermann T;Schnittger S;Bench A;Tobal K;Wilkins B;Cuthill K;McLornan D;Yeoman K;Akiki S;Bryon J;Jeffries S;Jones A;Percy MJ;Schwemmers S;Gruender A;Kelley TW;Reading S;Pancrazzi A;McMullin MF;Pahl HL;Cross NC;Harrison CN;Prchal JT;Chomienne C;Kiladjian JJ;Barbui T;Grimwade D (2013). Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM0902) study.. LEUKEMIA, vol. 27, pp. 2032-2039, ISSN:0887-6924
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Spolverini A;Pieri L;Guglielmelli P;Pancrazzi A;Fanelli T;Paoli C;Bosi A;Nichele I;Ruggeri M;Vannucchi AM (2013). Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis.. HAEMATOLOGICA, vol. 98, pp. e101-e102, ISSN:0390-6078
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Barbui T;Carobbio A;Finazzi G;Guglielmelli P;Salmoiraghi S;Rosti V;Rambaldi A;Vannucchi AM;Barosi G (2013). Elevated C-reactive protein is associated with shortened leukemia-free survival in patients with myelofibrosis.. LEUKEMIA, vol. 27, pp. 2084-2086, ISSN:0887-6924
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Guglielmelli P;Vannucchi AM (2013). Struggling with myelofibrosis-associated anemia.. LEUKEMIA RESEARCH, vol. 37, pp. 1429-1431, ISSN:0145-2126
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Vannucchi AM;Guglielmelli P (2013). JAK2 mutation-related disease and thrombosis.. SEMINARS IN THROMBOSIS AND HEMOSTASIS, vol. 39, pp. 496-506, ISSN:0094-6176
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Bartalucci N;Tozzi L;Bogani C;Martinelli S;Rotunno G;Villeval JL;Vannucchi AM (2013). Co-targeting the PI3K/mTOR and JAK2 signalling pathways produces synergistic activity against myeloproliferative neoplasms.. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 17, pp. 1385-1396, ISSN:1582-1838
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Marchioli R;Vannucchi AM;Barbui T (2013). Treatment target in polycythemia vera.. THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 368, pp. 1556-1556, ISSN:0028-4793
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Finazzi G;Vannucchi AM;Martinelli V;Ruggeri M;Nobile F;Specchia G;Pogliani EM;Olimpieri OM;Fioritoni G;Musolino C;Cilloni D;Sivera P;Barosi G;Finazzi MC;Di Tollo S;Demuth T;Barbui T;Rambaldi A (2013). A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 161, pp. 688-694, ISSN:0007-1048
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Vannucchi AM;Lasho TL;Guglielmelli P;Biamonte F;Pardanani A;Pereira A;Finke C;Score J;Gangat N;Mannarelli C;Ketterling RP;Rotunno G;Knudson RA;Susini MC;Laborde RR;Spolverini A;Pancrazzi A;Pieri L;Manfredini R;Tagliafico E;Zini R;Jones A;Zoi K;Reiter A;Duncombe A;Pietra D;Rumi E;Cervantes F;Barosi G;Cazzola M;Cross NC;Tefferi A (2013). Mutations and prognosis in primary myelofibrosis.. LEUKEMIA, vol. 27, pp. 1861-1869, ISSN:0887-6924
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Bogani C;Bartalucci N;Martinelli S;Tozzi L;Guglielmelli P;Bosi A;Vannucchi AM. (2013). mTOR inhibitors alone and in combination with JAK2 inhibitors effectively inhibit cells of myeloproliferative neoplasms.. PLOS ONE, vol. 8, pp. e54826-e54826, ISSN:1932-6203
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Bartalucci N;Guglielmelli P;Vannucchi AM (2013). Rationale for targeting the PI3K/Akt/mTOR pathway in myeloproliferative neoplasms.. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, vol. 13 Suppl 2, pp. 307-309, ISSN:2152-2650
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Cervantes F;Vannucchi AM;Kiladjian JJ;Al-Ali HK;Sirulnik A;Stalbovskaya V;McQuitty M;Hunter DS;Levy RS;Passamonti F;Barbui T;Barosi G;Harrison CN;Knoops L;Gisslinger H; (2013). Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis.. BLOOD, vol. 122, pp. 4047-4053, ISSN:0006-4971
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Harrison CN;Mesa RA;Kiladjian JJ;Al-Ali HK;Gisslinger H;Knoops L;Squier M;Sirulnik A;Mendelson E;Zhou X;Copley-Merriman C;Hunter DS;Levy RS;Cervantes F;Passamonti F;Barbui T;Barosi G;Vannucchi AM (2013). Health-related quality of life and symptoms in patients with myelofibrosis treated with ruxolitinib versus best available therapy.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 162, pp. 229-239, ISSN:0007-1048
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Tefferi A;Rumi E;Finazzi G;Gisslinger H;Vannucchi AM;Rodeghiero F;Randi ML;Vaidya R;Cazzola M;Rambaldi A;Gisslinger B;Pieri L;Ruggeri M;Bertozzi I;Sulai NH;Casetti I;Carobbio A;Jeryczynski G;Larson DR;Müllauer L;Pardanani A;Thiele J;Passamonti F;Barbui T (2013). Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study.. LEUKEMIA, vol. 27, pp. 1874-1881, ISSN:0887-6924
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Alessandro M. Vannucchi; Costanza Bogani; Niccolò Bartalucci (2013). JAK PI3K/mTOR COMBINATION THERAPY. Numero: US20130040973 A1 Incyte Corp., Novartis Pharma AG
Barbui T;Thiele J;Vannucchi AM;Tefferi A (2013). Problems and pitfalls regarding WHO-defined diagnosis of early/prefibrotic primary myelofibrosis versus essential thrombocythemia.. LEUKEMIA, vol. 27, pp. 1953-1958, ISSN:0887-6924
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Pieri L;Loiacono I;Vannucchi AM (2013). The burden of symptoms in myelofibrosis: from patient-reported outcomes to health economics.. LEUKEMIA RESEARCH, vol. 37, pp. 855-856, ISSN:0145-2126
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Rumi E;Pietra D;Guglielmelli P;Bordoni R;Casetti I;Milanesi C;Sant'Antonio E;Ferretti V;Pancrazzi A;Rotunno G;Severgnini M;Pietrelli A;Astori C;Fugazza E;Pascutto C;Boveri E;Passamonti F;De Bellis G;Vannucchi A;Cazzola M. (2013). Acquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasms.. BLOOD, vol. 121, pp. 4388-4395, ISSN:0006-4971
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Vittorio Rosti; Laura Villani; Roberta Riboni; Valentina Poletto; Elisa Bonetti; L. Tozzi; Gaetano Bergamaschi; Paolo Catarsi; Elena Dallera; Francesca Novara; Margherita Massa; Rita Campanelli; Gabriela Fois; Benedetta Peruzzi; Marco Lucioni; Paola Guglielmelli; Alessandro Pancrazzi; Giacomo Fiandrino; Orsetta Zuffardi; Umberto Magrini; Marco Paulli; A.M. Vannucchi ; Giovanni Barosi; (2012). Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation. BLOOD, vol. 0, pp. 0-0, ISSN:0006-4971
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Susini MC; Masala G; Antonioli E; Pieri L; Guglielmelli P; Palli D; Bosi A; Vannucchi AM (2012). Risk of second cancers in chronic myeloproliferative neoplasms. BLOOD, vol. 119, pp. 3861-3862, ISSN:0006-4971
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Milosevic JD; Puda A; Malcovati L; Berg T; Hofbauer M; Stukalov A; Klampf T; Harutyunyan AS; Gisslinger H; Gisslinger B; Burjanivova T; Rumi E; Pietra D; Elena C; Vannucchi AM; Doubek M; Dvorakova D; Robesova B; Wieser R; Koller E; Suvajdzic N; Tomin D; Tosic N; Colinge J; Racil Z; Steurer M; Pavlovic S; Cazzola M; Kralovics R (2012). Clinical significance of genetic aberrations in secondary acute myeloid leukemia. AMERICAN JOURNAL OF HEMATOLOGY, vol. 87, pp. 1010-1016, ISSN:1096-8652
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Spolverini A; Pieri L; Guglielmelli P; Pancrazzi A; Fanelli T; Paoli C;Bosi A; Vannucchi AM (2012). LNK MUTATIONS IN JAK2 NEGATIVE ERYTHROCYTOSIS. In: XII Congress of the Italian Society of Experimental Hematology, Roma, Ferrata Storti Foundation, pp. 128-128.
Vannucchi AM; Fanci R (2012). Fisiopatologia e morfologia del sangue e degli organi emopoietici. In: Bosi A, De Stefano V, Di Raimondo F, La Nasa G. Manuale di malattie del sangue, pp. 1-20, Milano: Elsevier, ISBN:9788821432620.
Vannucchi AM; Guglielmelli P (2012). Neoplasie mieloproliferative croniche Ph negative. In: Bosi A, De Stefano V, Di raimondo F, La Nasa G. Manuale di malattie del sangue, pp. 70-75, Milano: Elsevier, ISBN:9788821432620.
T. Barbui; J. Thiele; F. Passamonti; E. Rumi; E. Boveri; M.L. Randi; I. Bertozzi; F. Marino; A.M. Vannucchi; L. Pieri; G. Rotunno; H. Gisslinger; B. Gisslinger; L. Mullauer; G. Finazzi; A. Carobbio; A. Gianatti; M. Ruggeri; I. Nichele; E. D'Amore; A. Rambaldi; A. Tefferi (2012). Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome. BLOOD, vol. 119, pp. 2239-2241, ISSN:0006-4971
A. Carobbio; G. Finazzi; J. Thiele; H.M. Kvasnicka; F. Passamonti; E. Rumi; M. Ruggeri; F. Rodeghiero; M.L. Randi; I. Bertozzi; A.M. Vannucchi; E. Antonioli; H. Gisslinger; V. Buxhofer-Ausch; N. Gangat; A. Rambaldi; A. Tefferi; T. Barbui (2012). Blood tests may predict early primary myelofibrosis in patients presenting with essential thrombocythemia.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 87, pp. 203-204, ISSN:0361-8609
R.P. Gale; G. Barosi; T. Barbui; F. Cervantes; K. Dohner; B. Dupriez; V. Gupta; C. Harrison; R. Hoffman; J.J. Kiladjian; R. Mesa; M.F. Mc Mullin; F. Passamonti; V. Ribrag; G. Roboz; G. Saglio; A.M. Vannucchi; S. Verstovsek (2012). RBC-transfusion guidelines update. LEUKEMIA RESEARCH, vol. 36, pp. 659-660, ISSN:0145-2126
Antonioli, E; Guglielmelli, P; Pieri, L; Finazzi, M; Rumi, E; Martinelli, V; Vianelli, N; Randi, Ml; Bertozzi, I; De Stefano, V; Za, T; Rossi, E; Ruggeri, M; Elli, E; Cacciola, R; Cacciola, E; Pogliani, E; Rodeghiero, F; Baccarani, M; Passamonti, F; Finazzi, G; Rambaldi, A; Bosi, A; Cazzola, M; Barbui, T; Vannucchi, Am (2012). Hydroxyurea-related toxicity in 3,411 patients with Ph'-negative MPN. AMERICAN JOURNAL OF HEMATOLOGY, vol. 87, pp. 552-554, ISSN:0361-8609
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L. Villani;G. Bergamaschi;M. Primignani;V. Rosti;A. Carolei;V. Poletto;P. Catarsi;A. Spolverini;A.M. Vannucchi;G. Barosi. (2012). JAK2 46/1 haplotype predisposes tosplanchnic vein thrombosis-associated BCR-ABL negative classic myeloproliferativeneoplasms.. LEUKEMIA RESEARCH, vol. 36(1), pp. 7-9, ISSN:0145-2126
A. Tefferi; A. Pardanani; N. Gangat; K.H. Begna; C.A. Hanson; D.L. Van Dyke; D. Caramazza; A.M. Vannucchi; E. Morra; M. Cazzola; A. Pereira; F. Cervantes; F. Passamonti (2012). Leukemia risk models in primary myelofibrosis: an International Working Group study. LEUKEMIA, vol. 26, pp. 1439-1441, ISSN:0887-6924
A.M. Vannucchi (2012). Polycythemia Vera and Essential Thrombocythemia: When to Change Therapy - Second-Line Options. In: T. Barbui, A. Tefferi. Myeloproliferative Neoplasms. Critical Concepts and Management, pp. 119-129, Heidelberg: Springer, ISBN:9783642249884.
Barbui T; Finazzi G; Carobbio A; Thiele J; Passamonti F; Rumi E; Ruggeri M; Rodeghiero F; Randi ML; Bertozzi I; Gisslinger H; Buxhofer-Ausch V; De Stefano V; Betti S; Rambaldi A; Vannucchi AM; Tefferi A (2012). Development and validation of an International Prognostic Score of thrombosis in WHO-Essential thrombocythemia (IPSET-thrombosis. BLOOD, vol. 0, pp. 0-0, ISSN:0006-4971
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Barbui T; Thiele J; Carobbio A; Passamonti F; Rumi E; Randi ML; Bertozzi I; Vannucchi AM; Gisslinger H; Gisslinger B; Finazzi G; Ruggeri M; Rodeghiero F; Rambaldi A; Gangat N; Tefferi A. (2012). Disease characteristics and clinical outcome in young adults with essential thrombocythemia versus early /prefibrotic primary myelofibrosis. BLOOD, vol. 120, pp. 569-571, ISSN:0006-4971
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Vannucchi AM; Pieri L; Susini MC; Guglielmelli P (2012). BCR-ABL1-negative chronic myeloid neoplasms: an update on management techniques. FUTURE ONCOLOGY, vol. 8, pp. 575-593, ISSN:1479-6694
Susini, Mc; Masala, G; Antonioli, Elisabetta; Pieri, Lisa; Guglielmelli, P; Palli, D; Bosi, Alberto; Vannucchi, Am (2012). Risk of second cancers in chronic myeloproliferative neoplasms.. BLOOD, vol. 119, pp. 3861-3862, ISSN:0006-4971
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Passamonti F;Thiele J;Girodon F;Rumi E;Carobbio A;Gisslinger H;Kvasnicka HM;Ruggeri M;Randi ML;Gangat N;Vannucchi AM;Gianatti A;Gisslinger B;Müllauer L;Rodeghiero F;d'Amore ES;Bertozzi I;Hanson CA;Boveri E;Marino F;Maffioli M;Caramazza D;Antonioli E;Carrai V;Buxhofer-Ausch V;Pascutto C;Cazzola M;Barbui T;Tefferi A (2012). A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment.. BLOOD, vol. 120, pp. 1197-1201, ISSN:0006-4971
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Cervantes F; Dupriez B; Passamonti F; Vannucchi AM; Morra E; Reilly JT; Demory JL; Rumi E; Guglielmelli P; Roncoroni E; Tefferi A; Pereira A (2012). Improving survival trends in primary myelofibrosis: an international study. JOURNAL OF CLINICAL ONCOLOGY, vol. 30, pp. 2981-2987, ISSN:0732-183X
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C. Harrison; J.J. Kiladjian;H.K. Al-Ali; H.Gisslinger; R. Waltzman; V. Stalbovskaya; M. McQuitty; D. S. Hunter; R. Levy; L. Knoops; F. Cervantes; A.M. Vannucchi; T. Barbui; G. Barosi (2012). JAK Inhibition with Ruxolitinib versus Best Available Therapyfor Myelofibrosis. THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 366(9), pp. 787-798, ISSN:0028-4793
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Abdel-Wahab O; Pardanani A; Bernard OA; Finazzi G; Crispino JD; Gisslinger H; Kralovics R; Odenike O; Bhalla K; Gupta V; Barosi G; Gotlib J; Guglielmelli P; Kiladjian JJ; Noel P; Cazzola M; Vannucchi AM; Hoffman R; Barbui T; Thiele J; Van Etten RA; Mughal T; Tefferi A. (2012). Unraveling the genetic underpinnings of myeloproliferative neoplasms and understanding their effect on disease course and response to therapy: proceedings from the 6th International Post-ASH Symposium. AMERICAN JOURNAL OF HEMATOLOGY, vol. 87, pp. 562-568, ISSN:0361-8609
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C. Harrison; A.M. Vannucchi (2012). Ruxolitinib: a potent and selective Janus kinase 1 and 2 inhibitor in patients with myelofibrosis. An update for clinicians.. THERAPEUTIC ADVANCES IN HEMATOLOGY, vol. 3, pp. 341-354, ISSN:2040-6207
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A.Puda;J.D. Milosevic;T. Berg;T. Klampfl;A.S. Harutyunyan;B. Gisslinger;E. Rumi;D. Pietra;L. Malcovati;C. Elena;M. Doubek;M. Steurer;N. Tosic;S. Pavlovic;P. Guglielmelli;L. Pieri;A.M. Vannucchi;H. Gisslinger;M. Cazzola;R. Kralovics. (2012). Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 87, pp. 245-250, ISSN:0361-8609
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G. Finazzi;A. Carobbio;J. Thiele;F. Passamonti;E. Rumi;M. Ruggeri;F. Rodeghiero;M.L. Randi;I. Bertozzi;A.M. Vannucchi;E. Antonioli;H. Gisslinger;V. Buxhofer-Ausch;N. Gangat;A. Rambaldi;A. Tefferi;T. Barbui (2012). Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria.. LEUKEMIA, vol. 26, pp. 716-719, ISSN:0887-6924
Emanuel RM; Dueck AC; Geyer HL; Kiladjian JJ; Slot S; Zweegman S; Te Boekhorst PA; Commandeur S; Schouten HC; Sackmann F; Kerguelen Fuentes A; Hernández-Maraver D; Pahl HL; Griesshammer M; Stegelmann F; Doehner K; Lehmann T; Bonatz K; Reiter A; Boyer F; Etienne G; Ianotto JC; Ranta D; Roy L; Cahn JY; Harrison CN; Radia D; Muxi P; Maldonado N; Besses C; Cervantes F; Johansson PL; Barbui T; Barosi G; Vannucchi AM; Passamonti F; Andreasson B; Ferarri ML; Rambaldi A; Samuelsson J; Birgegard G; Tefferi A; Mesa RA. (2012). Myeloproliferative Neoplasm (MPN) Symptom Assessment Form Total Symptom Score: Prospective International Assessment of an Abbreviated Symptom Burden Scoring System Among Patients With MPNs.. JOURNAL OF CLINICAL ONCOLOGY, vol. 0, pp. 0-0, ISSN:0732-183X
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L. Pieri; M.L. Iorno; E. DiFonzo; F. Almerigogna; N. Pimpinelli; C. Cardinali; E. Antonioli; P. Guglielmelli; A. Bosi; P. Fabbri; A.M. Vannucchi (2012). Mastocitosi: approccio multidisciplinare a una patologia misconoscciuta. TOSCANA MEDICA, vol. XXIX (1), pp. 47-49, ISSN:2611-9412
T. Barbui; G. Barosi; V. De Stefabo; A. Falanga; G. Finazzi; F. Passamonti; M. Ruggeri; A.M. Vannucchi (2012). Le Neoplasie Mieloproliferative Philadelphia negative. Un approccio per problemi. In: T. Barbui, G. Barosi, V. De Stefabo, A. Falanga, G. Finazzi, F. Passamonti, M. Ruggeri, A.M. Vannucchi. Le Neoplasie Mieloproliferative Philadelphia negative. Un approccio per problemi, pp. 1-255, Milano: Oxys.
A.M. VANNUCCHI; C. BOGANI; P. GUGLIELMELLI; NOVARTIS PHARMA AG; INCYTE CORP. (2012). mTOR/JAK INHIBITOR COMBINATION THERAPY. Numero: 20120214825 A.M. VANNUCCHI, C. BOGANI, P. GUGLIELMELLI, NOVARTIS PHARMA AG, INCYTE CORP.
Godfrey AL; Chen E; Pagano F; Ortmann CA; Silber Y; Bellosillo B; Guglielmelli P; Harrison CN; Reilly T; Stegelman F; Bijoux F; Lippert E; McMullin MF; Boiron JM; Dohner K; Vannucchi AM; Besses C; Camplbell PJ; Green AR (2012). JAK2V617F-homozigosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant clone. BLOOD, vol. 120, pp. 2704-2707, ISSN:0006-4971
S. Bortoluzzi; A. Bisognin; M. Biasolo; P. Guglielmelli; F. Biamonte; R. Norfo; R. Manfredini; AM. Vannucchi (2012). Characterisation and discovery of novel miRNAs andmoRNAs in JAK2V617F mutated SET2 cells. BLOOD, vol. 119, pp. e120-e130, ISSN:0006-4971
Buxhofer-Ausch V; Gisslinger H; Thiele J; Gisslinger B; Kvasnicka HM; Müllauer L; Frantal S; Carobbio A; Passamonti F; Rumi E; Ruggeri M; Rodeghiero F; Randi ML; Bertozzi I; Vannucchi AM; Antonioli E; Finazzi G; Gangat N; Tefferi A; Barbui T. (2012). Leukocytosis as an important risk factor for arterial thrombosis in WHO-defined early/prefibrotic myelofibrosis: An international study of 264 patients.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 87, pp. 669-672, ISSN:0361-8609
G. Barosi;V. Rosti;A.M. Vannucchi (2011). Therapeutic approaches in myelofibrosis.. EXPERT OPINION ON PHARMACOTHERAPY, vol. 12(10), pp. 1597-1611, ISSN:1465-6566
A.M. Vannucchi (2011). Management of myelofibrosis.. HEMATOLOGY, vol. 2011, pp. 222-230, ISSN:1520-4391
A.M. Vannucchi (2011). Diagnosis and treatment of polcythenia vera and essential thrombocythemia. In: 16th congress of the European Hematology Association, pp. 255-263.
L. Pieri; A. Spolverini;B. Scappini;U. Occhini;S. Birtolo;A. Bosi;F. Albano;C. Fava;A.M. Vannucchi (2011). Concomitant occurrence of BCR-ABL and JAK2V617F mutation.. BLOOD, vol. 118(12), pp. 3445-3446, ISSN:0006-4971
Spolverini A; Jones AV; Hochhaus A; Pieri L; Cross NC; Vannucchi AM. (2011). The myeloproliferative neoplasm-associated JAK2 46/1 haplotype is not overrepresented in chronic myelogenous leukemia.. ANNALS OF HEMATOLOGY, vol. 90(3), pp. 365-366, ISSN:0939-5555
L. Varricchio;E. Masselli;E. Alfani;A. Battistini;G. Migliaccio;A.M. Vannucchi;W. Zhang;D. Rondelli;J. Godbold;B. Ghinassi;C. Whitsett; R. Hoffman; A.R.Migliaccio (2011). The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients.. BLOOD, vol. 118(2), pp. 425-436, ISSN:0006-4971
Vannucchi AM (2011). Management of myelofibrosis. In: 53rd Annual Meeting of the American Society of Hematology, pp. 222-228.
A.M. Vannucchi; E. Antonioli; P. Guglielmelli; L. Pieri; A. Pancrazzi; A. Bosi (2011). Percorsi diagnostici-terapeutici per le neoplasie mieloproliferative nella AOU Careggi. TOSCANA MEDICA, vol. xxix(4), pp. 46-48, ISSN:2611-9412
R.P. Gale;G. Barosi;T. Barbui;F. Cervantes;K. Dohner;B. Dupriez; V. Gupta;C. Harrison;R. Hoffman;J.J. Kiladjian;R. Mesa;M.F. Mc Mullin;F. Passamonti;V. Ribrag;G. Roboz;G. Saglio;A.M. Vannucchi;S.Verstovsek (2011). What are RBC-transfusion-dependence and -independence?. LEUKEMIA RESEARCH, vol. 35(1), pp. 8-11, ISSN:0145-2126
A.M. Vannucchi;F. Biamonte (2011). Epigenetics and mutations in chronic myeloproliferative neoplasms.. HAEMATOLOGICA, vol. 96(10), pp. 1398-1402, ISSN:0390-6078
F. Passamonti;C. Elena;S. Schnittger;R.C. Skoda;A.R. Green;F. Girodon;J.J. Kiladjian;M.F. McMullin;M. Ruggeri;C. Besses;A.M. Vannucchi;E. Lippert;H. Gisslinger;E. Rumi;T. Lehmann;C.A. Ortmann;D. Pietra;C. Pascutto;T. Haferlach;M. Cazzola (2011). Molecular and clinical features of the myeloproliferative neoplasm associated with JAK2 exon 12 mutations.. BLOOD, vol. 117(10), pp. 2813-2816, ISSN:0006-4971
A. Carobbio;J. Thiele;F. Passamonti;E. Rumi;M. Ruggeri; F. Rodeghiero;M.L. Randi;I. Bertozzi;A.M. Vannucchi;E. Antonioli;H. Gisslinger;V. Buxhofer-Ausch;G. Finazzi;N. Gangat;A. Tefferi;T. Barbui (2011). Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: an international study of 891 patients.. BLOOD, vol. 117(22), pp. 5857-5859, ISSN:0006-4971
Guglielmelli, P.; Tozzi, L.; Bogani, C.; Iacobucci, I.; Ponziani, V.; Martinelli, G.; Bosi, A.; Vannucchi, A.M. . (2011). Overexpression of microRNA-16-2 contributes to the abnormalerythropoiesis in polycythemia vera.. BLOOD, vol. 117(25), pp. 6923-6927, ISSN:0006-4971
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A. M. Vannucchi;L. Pieri;P. Guglielmelli (2011). JAK2 Allele Burden in the Myeloproliferative Neoplasms: Effects on Phenotype, Prognosis and Change with Treatment.. THERAPEUTIC ADVANCES IN HEMATOLOGY, vol. 2, pp. 21-32, ISSN:2040-6207
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C. Desterke;C. Bilhou-Nabéra;B. Guerton;C. Martinaud;C. Tonetti;D. Clay;P. Guglielmelli;A.M. Vannucchi;D. Bordessoule;H. Hasselbalch;B. Dupriez;N. Benzoubir;M.F. Bourgeade;O. Pierre-Louis;V. Lazar;W. Vainchenker;A. Bennaceur-Griscelli;H. Gisslinger;S. Giraudier;M.C. Le Bousse-Kerdilès. (2011). FLT3-mediated p38-MAPK activation participates in the control ofmegakaryopoiesis in primary myelofibrosis.. CANCER RESEARCH, vol. 71(11), pp. 4049-4050, ISSN:0008-5472
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A. Pardanani;P. Guglielmelli;T. Lasho;A. Pancrazzi;C.M. Finke;A.M. Vannucchi;A. Tefferi (2011). Primary myelofibrosis with or without mutant MPL: comparison ofsurvival and clinical features involving 603 patients.. LEUKEMIA, vol. 25(12), pp. 1834-1839, ISSN:0887-6924
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T. Klampfl;A. Harutyunyan;T. Berg;B. Gisslinger;M. Schalling;K. Bagienski;D. Olcaydu;F. Passamonti;E. Rumi;D. Pietra;R. Jäger;L. Pieri;P. Guglielmelli; I. Iacobucci;G. Martinelli;M. Cazzola;A.M. Vannucchi;H. Gisslinger;R. Kralovics. (2011). Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression.. BLOOD, vol. 118(1), pp. 167-176, ISSN:0006-4971
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T. Barbui;J. Thiele;F. Passamonti;E. Rumi;E. Boveri;M. Ruggeri;F. Rodeghiero;E.S. d'Amore;M.L. Randi;I. Bertozzi;F. Marino;A.M. Vannucchi;E. Antonioli;V. Carrai;H. Gisslinger;V. Buxhofer-Ausch;L. Müllauer;A. Carobbio;A. Gianatti;N. Gangat;C.A. Hanson;A. Tefferi (2011). Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis:an international study.. JOURNAL OF CLINICAL ONCOLOGY, vol. 29, pp. 3179-3184, ISSN:0732-183X
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Guglielmelli, Paola; Barosi, Giovanni; Rambaldi, Alessandro; Marchioli, Roberto; Masciulli, Arianna; Tozzi, Lorenzo; Biamonte, Flavia; Bartalucci, Niccolò; Gattoni, Elisabetta; Lupo, Maria Letizia; Finazzi, Guido; Pancrazzi, Alessandro; Antonioli, Elisabetta; Susini, Maria Chiara; Pieri, Lisa; Malevolti, Elisa; Usala, Emilio; Occhini, Ubaldo; Grossi, Alberto; Caglio, Silvia; Paratore, Simona; Bosi, Alberto; Barbui, Tiziano; Vannucchi, Alessandro M (2011). Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis. BLOOD, vol. 118, pp. 2069-2076, ISSN:0006-4971
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Tiziano Barbui; Giovanni Barosi; Gunnar Birgegard; Francisco Cervantes; Guido Finazzi; Martin Griesshammer; Claire Harrison; Hans Carl Hasselbalch; Rudiger Hehlmann; Ronald Hoffman; Jean-Jacques Kiladjian; Nicolaus Kröger; Ruben Mesa; Mary F. McMullin; Animesh Pardanani; Francesco Passamonti; Alessandro M. Vannucchi; Andreas Reiter; Richard T. Silver; Srdan Verstovsek; Ayalew Tefferi (2011). Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet.. JOURNAL OF CLINICAL ONCOLOGY, vol. 29, pp. 761-770, ISSN:0732-183X
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R. Scherber;A.C. Dueck;P. Johansson;T. Barbui;G. Barosi;A.M. Vannucchi;F. Passamonti;B. Andreasson;M.L. Ferarri;A. Rambaldi;J. Samuelsson;G. Birgegard;A. Tefferi;C.N. Harrison;D. Radia;R.A. Mesa (2011). The Myeloproliferative Neoplasm Symptom Assessment Form (MPN-SAF): international prospective validation and reliability trial in 402 patients.. BLOOD, vol. 118(2), pp. 401-408, ISSN:0006-4971
A. Pardanani;A.M. Vannucchi;F. Passamonti;F. Cervantes;T. Barbui;A. Tefferi (2011). JAK inhibitor therapy for myelofibrosis: critical assessment of value and limitations.. LEUKEMIA, vol. 25(2), pp. 218-225, ISSN:0887-6924
Barbui, T; Carobbio, A; Finazzi, G; Vannucchi, Am; Barosi, G; Antonioli, E; Guglielmelli, P; Pancrazzi, A; Salmoiraghi, S; Zilio, P (2011). Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3.. HAEMATOLOGICA, vol. 96(2), pp. 315-318, ISSN:0390-6078
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Biamonte F;Guglielmelli P;Fanelli T;Pancrazzi A;Villani L;Bosi A;Barosi G;Vannucchi AM (2011). ANALYSIS OF ASXL1 MUTATIONS IN 215 PATIENTS WITH MYELOFIBROSIS : IMPACT ON DISEASE PHENOTYPE AND PROGNOSIS. In: 43° Congress of the Italian Society of Hematology, Ferrata Storti Foundation, pp. 31-31.
Guglielmelli P; Biamonte F; Score J; Hidalgo-Curtis C; Cervantes F; Maffioli M; Fanelli T; Ernst T; Winkelman N; Jones AV; Zoi K; Reiter A; Duncombe A; Villani L; Bosi A; Barosi G; Cross NC; Vannucchi AM (2011). EZH2 mutational status predicts poor survival in myelofibrosis.. BLOOD, vol. 2011 Nov 10;118(19):5227-34., pp. 5227-5234, ISSN:0006-4971
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L. Gugliotta; A. Tieghi; G. Tortorella; P.R. Scalzulli;R. Ciancia;M. Lunghi; E. Cacciola; R. Cacciola; A. Candoni;M. Crugnola; K. Codeluppi; E. Usala;G. Specchia;V. Martinelli;F. Palmieri;I. Pierri;AM Liberati; A. Iurlo; A. Grossi; A.M. Vannucchi; N. Vianelli; M.G. Mazzucconi. (2011). Low impact of cardiovascular adverse events onanagrelide treatment discontinuation in a cohort of 232 patients with essential thrombocythemia.. LEUKEMIA RESEARCH, vol. 35(12), pp. 1557-1563, ISSN:0145-2126
Vannucchi AM. (2010). JAK2 mutation and thrombosis in the myeloproliferative neoplasms.. CURRENT HEMATOLOGIC MALIGNANCY REPORTS, vol. 5(1), pp. 22-28, ISSN:1558-8211
l. Pieri;P. Guglielmelli;A.M. Vannucchi (2010). Chronic myeloproliferative neoplasms: a collaborative approach.. MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, vol. 2(2), pp. e2010017-0, ISSN:2035-3006
Carobbio A; Finazzi G; Antonioli E; Vannucchi AM; Barosi G; Ruggeri M; Rodeghiero F; Delaini F; Rambaldi A; Barbui T. (2010). Hydroxyurea in essential thrombocythemia: rate and clinical relevance of responses by European LeukemiaNet criteria.. BLOOD, vol. 116(7), pp. 1051-1055, ISSN:0006-4971
Vannucchi AM. (2010). From palliation to targeted therapy in myelofibrosis.. THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 363(12), pp. 1180-1182, ISSN:0028-4793
Passamonti F; Cervantes F; Vannucchi AM; Morra E; Rumi E; Cazzola M; Tefferi A. (2010). Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis.. BLOOD, vol. 116(15), pp. 2857-2858, ISSN:0006-4971
P. Guglielmelli;F. Biamonte;A. Spolverini;L. Pieri;A. Isgrò;E. Antonioli;A. Pancrazzi;A. Bosi;G. Barosi;A.M. Vannucchi (2010). Frequency and clinical correlates of JAK2 46/1 (GGCC) haplotype in primary myelofibrosis.. LEUKEMIA, vol. 24(8), pp. 1533-1537, ISSN:0887-6924
P. Guglielmelli; A.M. Vannucchi (2010). Recent advances in diagnosis and treatment of chronic myeloproliferative neoplasms. F1000 MEDICINE REPORTS, vol. 2, pp. pii:16-pii:16, ISSN:1757-5931
Jones AV; Campbell PJ; Beer PA; Schnittger S; Vannucchi AM; Zoi K; Percy MJ; McMullin MF; Scott LM; Tapper W; Silver RT; Oscier D; Harrison CN; Grallert H; Kisialiou A; Strike P; Chase AJ; Green AR; Cross NC. (2010). The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms.. BLOOD, vol. 115(22), pp. 4517-4523, ISSN:0006-4971
Pieri L; Bosi A; Vannucchi AM. (2010). Imatinib and cardiac failure in idiopathic hypereosinophilic syndrome.. ANNALS OF HEMATOLOGY, vol. 89(7), pp. 745-746, ISSN:0939-5555
Rinaldi CR; Rinaldi P; Gemei M; Grimaldi F; Battipaglia G; Del Vecchio L; Martino B; Specchia G; Candoni A; Gugliotta L; Vannucchi AM; Barbui T; Pane F. (2010). JAK2V617F mutation persists in blasts and mature cells of transformed JAK2V617F-positive-myeloproliferative neoplasia: a European Leukemia Net (ENL) study.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 85(5), pp. 383-386, ISSN:0361-8609
Beer PA; Ortmann CA; Stegelmann F; Guglielmelli P; Reilly JT; Larsen TS; Hasselbalch H; Vannucchi AM; Moller P; Dohner K; Green A. (2010). Molecular mechanisms associated with leukaemic transformation of MPL-mutant myeloproliferative neoplasms.. HAEMATOLOGICA, vol. 95(12), pp. 2153-2156, ISSN:0390-6078
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Barbui T; Carobbio A; Cervantes F; Vannucchi AM; Guglielmelli P; Antonioli E; Alvarez-Larran A; Rambaldi A; Finazzi G; Barosi G. (2010). Thrombosis in primary myelofibrosis: incidence and risk factors.. BLOOD, vol. 115, pp. 778-782, ISSN:0006-4971
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Passamonti F; Cervantes F; Vannucchi AM; Morra E; Rumi E; Pereira A; Guglielmelli P; Pungolino E; Caramella M; Maffioli M; Pascutto C; Lazzarino M; Cazzola M; Tefferi A. (2010). A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment).. BLOOD, vol. 115, pp. 1703-1708, ISSN:0006-4971
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Verrucci M; Pancrazzi A; Aracil M; Martelli F; Guglielmelli P; Zingariello M; Ghinassi B; D'Amore E; Jimeno J; Vannucchi AM; Migliaccio AR. (2010). CXCR4-independent rescue of the myeloproliferative defect of the Gata1low myelofibrosis mouse model by Aplidin.. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 225(2), pp. 490-499, ISSN:0021-9541
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Tefferi A; Lasho TL; Abdel-Wahab O; Guglielmelli P; Patel J; Caramazza D; Pieri L; Finke CM; Kilpivaara O; Wadleigh M; Mai M; McClure RF; Gilliland DG; Levine RL; Pardanani A; Vannucchi AM. (2010). IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis.. LEUKEMIA, vol. 24(7), pp. 1302-1309, ISSN:0887-6924
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Rambaldi A; Dellacasa CM; Finazzi G; Carobbio A; Ferrari ML; Guglielmelli P; Gattoni E; Salmoiraghi S; Finazzi MC; Di Tollo S; D'Urzo C; Vannucchi AM; Barosi G; Barbui T. (2010). A pilot study of the Histone-Deacetylase inhibitor Givinostat in patients with JAK2V617F positive chronic myeloproliferative neoplasms.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 150(4), pp. 446-455, ISSN:0007-1048
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Vannucchi AM; Guglielmelli P. (2010). Advances in understanding and management of polycythemia vera.. CURRENT OPINION IN ONCOLOGY, vol. 22(6), pp. 636-641, ISSN:1040-8746
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Vannucchi AM. (2010). Insights into pathogenesis and management of thrombosis in polycythemia vera and essential thrombocythemia. Internal and Emergency medicine. INTERNAL AND EMERGENCY MEDICINE, vol. 5(3), pp. 177-184, ISSN:1970-9366
Gianfaldoni G; Mannelli F; Ponziani V; Longo G; Bencini S; Bosi A; Vannucchi AM. (2010). Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia.. HAEMATOLOGICA, vol. 95(8), pp. 1435-1438, ISSN:0390-6078
Gianfaldoni G;Mannelli F;Ponziani V;Longo G;Bencini S;Bosi A;Vannucchi AM (2010). Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia.. HAEMATOLOGICA, vol. 95, pp. 833-836, ISSN:0390-6078
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Antonioli E; Carobbio A; Pieri L; Pancrazzi A; Guglielmelli P; Delaini F; Ponziani V; Bartalucci N; Tozzi L; Bosi A; Rambaldi A; Barbui T; Vannucchi A (2010). Hydroxyurea does not appreciably reduce JAK2 V617F allele burden in patients with polycythemia vera or essential thrombocythemia.. HAEMATOLOGICA, vol. 95, pp. 1435-1438, ISSN:0390-6078
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Barosi G; Gattoni E; Guglielmelli P; Campanelli R; Facchetti F; Fisogni S; Goldberg J; Marchioli R; Hoffman R; Vannucchi AM. (2010). Phase I/II study of single-agent bortezomib for the treatment of patients with myelofibrosis. Clinical and biological effects of proteasome inhibition.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 85(8), pp. 616-619, ISSN:0361-8609
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Barosi G; Birgegard G; Finazzi G; Griesshammer M; Harrison C; Hasselbalch H; Kiladijan JJ; Lengfelder E; Mesa R; Mc Mullin MF; Passamonti F; Reilly JT; Vannucchi AM; Barbui T. (2010). A unified definition of clinical resistance and intolerance to hydroxycarbamide in polycythaemia vera and primary myelofibrosis: results of a European LeukemiaNet (ELN) consensus process.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 148(6), pp. 961-963, ISSN:0007-1048
Beer PA; Delhommeau F; Lecouedic JP; Dawson MA; Chen E; Bareford D; Kusec R; McMullin MF; Harrison CN; Vannucchi AM; Vainchenker W; Green AR. (2010). Two routes to leukemic transformation following a JAK2 mutation-positive myeloproliferative neoplasm. BLOOD, vol. 115(14), pp. 2891-2900, ISSN:0006-4971
De Stefano V; Za T; Rossi E; Vannucchi AM; Ruggeri M; Elli E; Micò C; Tieghi A; Cacciola RR; Santoro C; Gerli G; Guglielmelli P; Pieri L; Scognamiglio F; Rodeghiero F; Pogliani EM; Finazzi G; Gugliotta L; Leone G; Barbui T. (2010). Leukocytosis is a risk factor for recurrent arterial thrombosis in young patients with polycythemia vera and essential thrombocythemia.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 85(2), pp. 97-100, ISSN:0361-8609
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V. Rosti; E. Bonetti; G. Bergamaschi; R. Campanelli; P. Guglielmelli; M. Maestri;U. Magrini; M. Massa; C. Tinelli; G. Viarengo; L. Villani; M. Primignani; A.M. Vannucchi; F. Frassoni; G. Barosi. (2010). High frequency of endothelial colony forming cells marks a non-active myeloproliferative neoplasm with high risk ofsplanchnic vein thrombosis.. PLOS ONE, vol. 5, pp. e15277-e15277, ISSN:1932-6203
Ghinassi B; Martelli F; Verrucci M; D'Amore E; Migliaccio G; Vannucchi AM; Hoffman R; Migliaccio AR. (2010). Evidence for organ-specific stem cell microenvironments.. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 223(2), pp. 460-470, ISSN:0021-9541
Vannucchi AM; Masala G; Antonioli E; Chiara Susini M; Guglielmelli P; Pieri L; Maggi L; Caini S; Palli D; Bogani C; Ponziani V; Pancrazzi A; Annunziato F; Bosi A. (2009). Increased risk of lymphoid neoplasms in patients with Philadelphia chromosome-negative myeloproliferative neoplasms.. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, vol. 18(7), pp. 2068-2073, ISSN:1055-9965
Barbara Ghinassi; Maria Zingariello; Fabrizio Martelli; Rodolfo Lorenzini; Alessandro M Vannucchi; Rosa Alba Rana; Mitsuo Nishikawa; Giovanni Migliaccio; John Mascarenhas; Anna Rita Migliaccio (2009). Increased differentiation of dermal mast cells in mice lacking the Mpl gene.. STEM CELLS AND DEVELOPMENT, vol. 18, pp. 1081-1092, ISSN:1547-3287
Olcaydu D; Skoda RC; Looser R; Li S; Cazzola M; Pietra D; Passamonti F; Lippert E; Carillo S; Girodon F; Vannucchi A; Reading NS; Prchal JT; Ay C; Pabinger I; Gisslinger H; Kralovics R. (2009). The “GGCC” haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation positive polycythemia vera. LEUKEMIA, vol. 23, pp. 1924-1926, ISSN:0887-6924
Vannucchi AM. (2009). How JAK2-inhibitors work in myelofibrosis: an alternative hypothesis.. LEUKEMIA RESEARCH, vol. 33, pp. 1581-1583, ISSN:0145-2126
Francisco Cervantes; Brigitte Dupriez; Arturo Pereira; Francesco Passamonti; John T Reilly; Enrica Morra; Alessandro M Vannucchi; Ruben A Mesa; Jean-Loup Demory; Giovanni Barosi; Elisa Rumi; Ayalew Tefferi (2009). A new prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment.. BLOOD, vol. 113, pp. 2895-2901, ISSN:0006-4971
Barosi G; Birgegard G; Finazzi G; Griesshammer M; Harrison C; Hasselbalch HC; Kiladjian JJ; Lengfelder E; McMullin MF; Passamonti F; Reilly JT; Vannucchi AM; Barbui T. (2009). Response criteria for essential thrombocythemia and polycythemia vera. Result of a European LeukemiaNet (ELN) consensus conference. BLOOD, vol. 113, pp. 4829-4833, ISSN:0006-4971
C. Cellai; A. Laurenzana; E. Bianchi; S. Sdelci; R. Manfredini; A.M. Vannucchi; R. Caporale; M. Balliu; F. Mannelli; S. Ferrari; A. Bosi; D. Miniat; P.L. Cocco; S. Veronneau; J. Stankova; F. Paoletti (2009). Mechanistic insight into WEB-2170-induced apoptosis in human acute myelogenous leukemia cells: the crucial role of PTEN. EXPERIMENTAL HEMATOLOGY, vol. 37, pp. 1176-1185, ISSN:0301-472X
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Accesso ONLINE all'editore
P. Guglielmelli; G. Barosi; L. Pieri; E. Antonioli; A. Bosi; A.M. Vannucchi (2009). JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis. HAEMATOLOGICA, vol. 94, pp. 144-146, ISSN:0390-6078
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De Stefano V; Za T; Rossi E; Vannucchi AM; Ruggeri M; Elli E; Micò C; Tieghi A; Cacciola RR; Santoro C; Vianelli N; Guglielmelli P; Pieri L; Scognamiglio F; Cacciola E; Rodeghiero F; Pogliani EM; Finazzi G; Gugliotta L; Leone G; Barbui T (2009). Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation. ANNALS OF HEMATOLOGY, vol. 89, pp. 141-146, ISSN:0939-5555
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Carobbio A; Finazzi G; Antonioli E; Guglielmelli P; Vannucchi AM; Dellacasa CM; Salmoiraghi S; Delaini F; Rambaldi A; Barbui T. (2009). JAK2V617F allele burden and thrombosis: a direct comparison in Essential Thrombocythemia and Polycythemia Vera. EXPERIMENTAL HEMATOLOGY, vol. 37, pp. 1016-1021, ISSN:0301-472X
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De Stefano, V; Za, T; Rossi, E; Vannucchi, Am; Ruggeri, M; Elli, E; Micò, C; Tieghi, A; Cacciola, Rr; Santoro, C; Vianelli, N; Guglielmelli, P; Pieri, L; Scognamiglio, F; Cacciola, E; Rodeghiero, F; Pogliani, Em; Finazzi, G; Gugliotta, L; Leone, G; Barbui, T; Bosi, A; Ruggeri, M; Scognamiglio, F (2009). Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation.. ANNALS OF HEMATOLOGY, pp. 141-146, ISSN:0939-5555
Pieri L1; Bogani C; Guglielmelli P; Zingariello M; Rana RA; Bartalucci N; Bosi A; Vannucchi AM (2009). The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera.. HAEMATOLOGICA, pp. 1537-1545, ISSN:0390-6078
Migliaccio AR; Martelli F; Verrucci M; Sanchez M; Valeri M; Migliaccio G; Vannucchi AM; Zingariello M; Di Baldassarre A; Ghinassi B; Rana RA; van Hensbergen Y; Fibbe WE. (2009). GATA1 expression driven by the alternative hs2 enhancer in the spleen rescues the hematopoietic failure induced by the hypomorphic GATA1low mutation. BLOOD, vol. 114, pp. 2107-2120, ISSN:0006-4971
Guglielmelli P; Barosi G; Specchia G; Rambaldi A; Lo Coco F; Antonioli E; Pieri L; Pancrazzi A; Ponziani V; Delaini F; Longo G; Ammatuna E; Liso V; Bosi A; Barbui T; Vannucchi AM. (2009). Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele.. BLOOD, vol. 114, pp. 1477-1483, ISSN:0006-4971
Martelli F; Verrucci M; Migliaccio G; Zingariello M; Rana RA; Vannucchi AM; Migliaccio AR. (2009). Removal of the spleen in mice alters the cytokine expression profile of the marrow micro-environment and increases bone formation.. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 1176, pp. 77-86, ISSN:0077-8923
Intermesoli T; Delaini F; Acerboni S; Salmoiraghi S; Spinelli O; Guerini V; Vannucchi AM; Mappa S; Rossi G; Rossi V; Di Bona E; Paratore S; Carobbio A; Rambaldi A; Barbui T; Bassan R. (2009). A short low-dose imatinib trial allows rapid identification of responsive patients in hypereosinophilic syndromes.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 147, pp. 681-685, ISSN:0007-1048
A.M. Vannucchi; P. Guglielmelli; A. Tefferi (2009). Advances in understanding and management of myeloproliferative neoplasms. CA, vol. 59, pp. 171-191, ISSN:0007-9235
L. Catani; R. Zini; D. Solazzo; E. Ottaviani; A.M. Vannucchi; S. ferrari; M. Baccarani; N. Vianelli; R.M. Lemoli; R. Manfredini (2009). Molecular profile of CD34+ stem/progenitor cells according to JAK2V617F mutation status in essential thrombocythemia.. LEUKEMIA, vol. 23, pp. 997-1000, ISSN:0887-6924
Vannucchi AM; Guglielmelli P; Rambaldi A; Bogani C; Barbui T. (2009). Epigenetic therapy in myeloproliferative neoplasms: evidence and perspectives. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 13, pp. 1437-1450, ISSN:1582-1838
Goldman JM; Green AR; Holyoake T; Jamieson C; Mesa R; Mughal T; Pellicano F; Perrotti D; Skoda R; Vannucchi AM. (2009). Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.. LEUKEMIA, vol. 23, pp. 1708-1715, ISSN:0887-6924
P. Guglielmelli; C. Fatini; M. Lenti; A. Bosi; A.M. Vannucchi (2009). JAK2V617F mutational screening in patients with retinal vein thrombosis or recurrent fetal loss.. THROMBOSIS RESEARCH, vol. 124, pp. 377-378, ISSN:0049-3848
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A.M. Vannucchi; P. Guglielmelli; L. Pieri; E. Antonioli; A. Bosi (2009). Treatment options for essential thrombocythemia and polycythemia vera. EXPERT REVIEW OF HEMATOLOGY, vol. 2, pp. 41-55, ISSN:1747-4086
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L. Pieri ; C. Bogani ; P. Guglielmelli ; M. Zingariello ; RA. Rana ; N. Bartalucci ;A Bosi ; AM. Vannucchi (2009). The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils of polycythemia vera.. HAEMATOLOGICA, vol. 94, pp. 1537-1545, ISSN:0390-6078
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M. Verrucci; A.R. Migliaccio; A.M. Vannucchi; J.M. Jimeno Donaque (2009). Aplidine in the treatment of chronic myeloproliferative disorders. PHARMA MAR S.A., M. Verrucci, A.R. Migliaccio, A.M. Vannucchi, J.M. Jimeno Donaque
A.M. Vannucchi; T. Barbui (2008). Startified management of essential thrombocythemia and polycythemia vera. In: 13th Congress of the European Society of Hematology association, pp. 201-208.
Anna Rita Migliaccio; Fabrizio Martelli; Maria Verrucci; Giovanni Migliaccio; Alessandro Maria Vannucchi; Hongyu Ni; Mingjiang Xu; Yi Jiang; Betty Nakamoto; Thalia Papayannopoulou; Ronald Hoffman (2008). Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1 low mouse model of the disease.. EXPERIMENTAL HEMATOLOGY, vol. 36, pp. 158-171, ISSN:0301-472X
A.M. Vannucchi (2008). JAK2: how many faces in MPDs?. BLOOD, vol. 111, pp. 2499-2499, ISSN:0006-4971
Alessandro M Vannucchi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro Pancrazzi; Vittoria Guerini; Giovanni Barosi; Marco Ruggeri; Giorgina Specchia; Francesco Lo-Coco; Federica Delaini; Laura Villani; Silvia Finotto; Emanuele Ammatuna; Renato Alterini; Valentina Carrai; Gloria Capaccioli; Simonetta Di Lollo; Vincenzo Liso; Alessandro Rambaldi; Alberto Bosi; Tiziano Barbui (2008). Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia.. BLOOD, vol. 112, pp. 844-847, ISSN:0006-4971
Alessandro Pancrazzi; Paola Guglielmelli; Vanessa Ponziani; Gaetano Bergamaschi; Alberto Bosi; Giovanni Barosi; Alessandro M Vannucchi (2008). A sensitive detection method for MPLW515L or MPLW515K mutation in chronic myeloproliferative disorders with locked nucleic acid-modified probes and real-time polymerase chain reaction.. THE JOURNAL OF MOLECULAR DIAGNOSTICS, vol. 10, pp. 435-441, ISSN:1525-1578
Lisa Pieri; Paola Guglielmelli; Costanza Bogani; Alberto Bosi; Alessandro M Vannucchi; (2008). Mesenchymal stem cells from JAK2(V617F) mutant patients with primary myelofibrosis do not harbor JAK2 mutant allele.. LEUKEMIA RESEARCH, vol. 32, pp. 516-517, ISSN:0145-2126
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A. M. Vannucchi; E. Antonioli; P. Guglielmelli; A. Pardanani; A. Tefferi (2008). Clinical correlates of JAK2V617F presence or allele burden in myeloproliferative neoplasms: a critical reappraisal.. LEUKEMIA, vol. 22, pp. 1299-1307, ISSN:0887-6924
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Costanza Bogani; Vanessa Ponziani; Paola Guglielmelli; Cristophe Desterke; Vittorio Rosti; Alberto Bosi; Marie-Caroline Le Bousse-Kerdilès; Giovanni Barosi; Alessandro M Vannucchi. (2008). Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis.. STEM CELLS, vol. 26, pp. 1920-1930, ISSN:1066-5099
De Stefano V; Za T; Rossi E; Vannucchi AM; Ruggeri M; Elli E; Micò C; Tieghi A; Cacciola RR; Santoro C; Gerli G; Vianelli N; Guglielmelli P; Pieri L; Scognamiglio F; Rodeghiero F; Pogliani EM; Finazzi G; Gugliotta L; Marchioli R; Leone G; Barbui T (2008). Recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia: incidence, risk factors, and effect of treatments.. HAEMATOLOGICA, vol. 93, pp. 372-380, ISSN:0390-6078
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Accesso ONLINE all'editore
PANCRAZZI A; AM VANNUCCHI; V. PONZIANI; P. GUGLIELMELLI (2008). ANALISI MUTAZIONALI DELLE MALATTIE MIELOPROLIFERTAIVE CRONICHE. Università di Firenze
Marco Ruggeri; Francesco Rodeghiero; Alberto Tosetto; Giancarlo Castaman; Francesca Scognamiglio; Guido Finazzi; Federica Delaini; Caterina Micò; Alessandro M Vannucchi; Elisabetta Antonioli; Valerio De Stefano; Tommaso Za; Luigi Gugliotta; Alessia Tieghi; Maria Gabriella Mazzucconi; Cristina Santoro; Tiziano Barbui; (2008). Postsurgery outcomes in patients with polycythemia vera and essential thrombocythemia: a retrospective survey.. BLOOD, vol. 111, pp. 666-671, ISSN:0006-4971
G. Barosi; R. A. Mesa; J. Thiele; F. Cervantes; P. J. Campbell; S. Verstovsek; B. Dupriez; R. L. Levine; F. Passamonti; J. Gotlib; J. T. Reilly; A. M. Vannucchi; C. A. Hanson; L. A. Solberg; A. Orazi; A. Tefferi; International Working Group; Treatment (IWG-MRT) (2008). Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment.. LEUKEMIA, vol. 22, pp. 437-438, ISSN:0887-6924
A. Carobbio; G. Finazzi; E. Antonioli; P. Guglielmelli; A.M. Vannucchi; F. Delaini; V. Guerini; M. Ruggeri; F. Rodeghiero; A. Rambaldi; T. Barbui (2008). Thrombocytosis and leukocytosis interactions in vascular complications of essential thrombocythemia. BLOOD, vol. 112(8), pp. 3135-3137, ISSN:0006-4971
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Elisabetta Antonioli; Paola Guglielmelli; Giada Poli; Costanza Bogani; Alessandro Pancrazzi; Giovanni Longo; Vanessa Ponziani; Lorenzo Tozzi; Lisa Pieri; Valeria Santini; Alberto Bosi; Alessandro M Vannucchi. (2008). Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia.. HAEMATOLOGICA, vol. 93, pp. 41-48, ISSN:0390-6078
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V. Ponziani; F. Mannelli; N. Bartalucci; G. Gianfaldoni; F. Leoni; E. Antonioli; P. Guglielmelli; S. Ciolli; A. Bosi; A. M. Vannucchi (2008). No role for CXCL12-G801A polymorphism in the development of extramedullary disease in acute myeloid leukemia.. LEUKEMIA, vol. 22, pp. 669-671, ISSN:0887-6924, Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358:
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Alessandra Carobbio; Elisabetta Antonioli; Paola Guglielmelli; Alessandro M Vannucchi; Federica Delaini; Vittoria Guerini; Guido Finazzi; Alessandro Rambaldi; Tiziano Barbui (2008). Leukocytosis and risk stratification assessment in essential thrombocythemia.. JOURNAL OF CLINICAL ONCOLOGY, vol. 26, pp. 2732-2736, ISSN:0732-183X
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Alessandro M Vannucchi; Paola Guglielmelli (2008). Molecular pathophysiology of Philadelphia-negative myeloproliferative disorders: beyond JAK2 and MPL mutations.. HAEMATOLOGICA, vol. 93, pp. 972-976, ISSN:0390-6078
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Fabrizio Martelli; Barbara Ghinassi; Rodolfo Lorenzini; Alessandro M Vannucchi; Rosa Alba Rana; Mitsuo Nishikawa; Sandra Partamian; Giovanni Migliaccio; Anna Rita Migliaccio (2008). Thrombopoietin inhibits murine mast cell differentiation.. STEM CELLS, vol. 26, pp. 912-919, ISSN:1066-5099
Vittorio Rosti; Margherita Massa; Alessandro M Vannucchi; Gaetano Bergamaschi; Rita Campanelli; Alessandro Pecci; Gianluca Viarengo; Valentina Meli; Monia Marchetti; Paola Guglielmelli; Edward Bruno; Mingjiang Xu; Ronald Hoffman; Giovanni Barosi. (2007). The expression of CXCR4 is down-regulated on the CD34+ cells of patients with myelofibrosis with myeloid metaplasia.. BLOOD CELLS, MOLECULES, & DISEASES, vol. 38, pp. 280-286, ISSN:1079-9796
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A.M. Vannucchi (2007). Biologia molecolare delle malattie mieloproliferative croniche Ph Negative tipiche. In: 41° Congresso Nazionale Società Italiana di Ematologia, vol. Libro degli atti, pp. 164-172.
Alessandro M. Vannucchi; Alessandro Pancrazzi; paola guglielmelli; Vanessa Ponziani (2007). Analisi mutazionale delle malattie mieloproliferative croniche. Numero: FI2007A000274; PCT IB2008/055122 Università di Firenze
Alessandro M Vannucchi; Tiziano Barbui (2007). Thrombocytosis and thrombosis.. HEMATOLOGY, vol. 2007, pp. 363-370, ISSN:1520-4391
Eva Zetterberg; Alessandro M Vannucchi; Anna Rita Migliaccio; William Vainchenker; Micheline Tulliez; Renée Dickie; Hans Hasselbalch; Rick Rogers; Jan Palmblad (2007). Pericyte coverage of abnormal blood vessels in myelofibrotic bone marrows.. HAEMATOLOGICA, vol. 92, pp. 597-604, ISSN:0390-6078
Barbara Ghinassi; Massimo Sanchez; Fabrizio Martelli; Giovanni Amabile; Alessandro Maria Vannucchi; Giovanni Migliaccio; Stuart H Orkin; Anna Rita Migliaccio (2007). The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor.. BLOOD, vol. 109, pp. 1460-1471, ISSN:0006-4971
Vannucchi Alessandro Maria; Pancrazi Alessandro; Guglielmelli Paola; Ponziani Vanessa (2007). MPL mutational analysis in chronic myeloproliferative disorders. Numero: WO2009072084 A2 Vannucchi Alessandro Maria, Pancrazi Alessandro, Guglielmelli Paola, Ponziani Vanessa
PIERI L; GUGLIELMELLI P; BOGANI C; A. BOSI; VANNUCCHI AM; FOR THE MYELOPROLIFERATIVE DISORDERS RESEARCH CONSORTIUM MPD-RC (2007). Mesenchymal stem cells from JAK2(V617F) mutant patients with primary myelofibrosis do not harbor JAK2 mutant allele. LEUKEMIA RESEARCH, vol. 32, pp. 516-517, ISSN:0145-2126, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:
Giovanni Barosi; Gaetano Bergamaschi; Monia Marchetti; Alessandro M Vannucchi; Paola Guglielmelli; Elisabetta Antonioli; Margherita Massa; Vittorio Rosti; Rita Campanelli; Laura Villani; Gianluca Viarengo; Elisabetta Gattoni; Giancarla Gerli; Giorgina Specchia; Carmine Tinelli; Alessandro Rambaldi; Tiziano Barbui. (2007). JAK2 V617F mutational status predicts progression to large splenomegaly and leukemic transformation in primary myelofibrosis.. BLOOD, vol. 110, pp. 4030-4036, ISSN:0006-4971
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Elisabetta Antonioli; Paola Guglielmelli; Giada Poli; Valeria Santini; Alberto Bosi; Alessandro M Vannucchi (2007). Polycythemia vera following autologous transplantation for AML: insights on the kinetics of JAK2V617F clonal dominance.. BLOOD, vol. 110, pp. 4620-4621, ISSN:0006-4971
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A. M. Vannucchi; S. Guidi; P. Guglielmelli; S. Glinz; L. Lombardini; A. Busca; F. Locatelli; A. M. Dall'Omo; A. Bosi (2007). Significance of CTLA-4 and CD14 genetic polymorphisms in clinical outcome after allogeneic stem cell transplantation.. BONE MARROW TRANSPLANTATION, vol. 40, pp. 1001-1002, ISSN:0268-3369
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A.M. Vannucchi; J-L- Villeval; O. Wagner-Ballon; P. Guglielmelli; A.R. Migliaccio (2007). Animal models of myelofibrosis. In: M.P. Conn. Sourcebook of models for biomedical research, pp. 713-723, Totowa NJ, Human Press Inc.: P.M. Conn, ISBN:978-1-59745-285-4.
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Alessandro M Vannucchi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro Rambaldi; Giovanni Barosi; Roberto Marchioli; Rosa Maria Marfisi; Guido Finazzi; Vittoria Guerini; Fabrizio Fabris; Maria Luigia Randi; Valerio De Stefano; Sabrina Caberlon; Agostino Tafuri; Marco Ruggeri; Giorgina Specchia; Vincenzo Liso; Edoardo Rossi; Enrico Pogliani; Luigi Gugliotta; Alberto Bosi; Tiziano Barbui (2007). Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia.. BLOOD, vol. 110, pp. 840-846, ISSN:0006-4971
Ayalew Tefferi; Juergen Thiele; Attilio Orazi; Hans Michael Kvasnicka; Tiziano Barbui; Curtis A Hanson; Giovanni Barosi; Srdan Verstovsek; Gunnar Birgegard; Ruben Mesa; John T Reilly; Heinz Gisslinger; Alessandro M Vannucchi; Francisco Cervantes; Guido Finazzi; Ronald Hoffman; D. Gary Gilliland; Clara D Bloomfield; James W Vardiman (2007). Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel.. BLOOD, vol. 110, pp. 1092-1097, ISSN:0006-4971
Anna Rita Migliaccio; Rosa Alba Rana; Alessandro M Vannucchi; Francesco A Manzoli (2007). Role of thrombopoietin in mast cell differentiation.. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 1106, pp. 152-174, ISSN:0077-8923
A.M. Vannucchi; P. Guglielmelli (2007). Regolazione dell’emopoiesi. In: A. Bosi. Il sangue cordonale, pp. 41-63, Firenze, SEE Editrice: A. Bosi.
Paola Guglielmelli; Roberta Zini; Costanza Bogani; Simona Salati; Alessandro Pancrazzi; Elisa Bianchi; Francesco Mannelli; Sergio Ferrari; Marie-Caroline Le Bousse-Kerdilès; Alberto Bosi; Giovanni Barosi; Anna Rita Migliaccio; Rossella Manfredini; Alessandro M Vannucchi (2007). Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).. STEM CELLS, vol. 25, pp. 165-173, ISSN:1066-5099
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Marcello Di Nisio; Tiziano Barbui; Leonardo Di Gennaro; Giovanna Borrelli; Guido Finazzi; Raffaele Landolfi; Giuseppe Leone; Rosamaria Marfisi; Ettore Porreca; Marco Ruggeri; Anne W S; Gianni Tognoni; Alessandro M Vannucchi; Roberto Marchioli; (2007). The haematocrit and platelet target in polycythemia vera.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 136, pp. 249-259, ISSN:0007-1048
Ruben A Mesa; Srdan Verstovsek; Francisco Cervantes; Giovanni Barosi; John T Reilly; Brigitte Dupriez; Ross Levine; Marie-Caroline Le Bousse-Kerdiles; Martha Wadleigh; Peter J Campbell; Richard T Silver; Alessandro M Vannucchi; H. Joachim Deeg; Heinz Gisslinger; Deborah Thomas; Olatoyosi Odenike; Lawrence A Solberg; Jason Gotlib; Elizabeth Hexner; Stephen D Nimer; Hagop Kantarjian; Attilio Orazi; James W Vardiman; Juergen Thiele; Ayalew Tefferi; (2007). Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): Consensus on terminology by the international working group for myelofibrosis research and treatment (IWG-MRT).. LEUKEMIA RESEARCH, vol. 31, pp. 737-740, ISSN:0145-2126
Costanza Bogani; Paola Guglielmelli; Elisabetta Antonioli; Alessandro Pancrazzi; Alberto Bosi; Alessandro Maria Vannucchi (2007). B-, T-, and NK-cell lineage involvement in JAK2V617F-positive patients with idiopathic myelofibrosis.. HAEMATOLOGICA, vol. 92, pp. 258-259, ISSN:0390-6078
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A. M. Vannucchi; E. Antonioli; P. Guglielmelli; G. Longo; A. Pancrazzi; V. Ponziani; C. Bogani; P. R. Ferrini; A. Rambaldi; V. Guerini; A. Bosi; T. Barbui. (2007). Prospective identification of high-risk polycythemia vera patients based on JAK2(V617F) allele burden.. LEUKEMIA, vol. 21, pp. 1952-1959, ISSN:0887-6924
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Paola Guglielmelli; Lorenzo Tozzi; Alessandro Pancrazzi; Costanza Bogani; Elisabetta Antonioli; Vanessa Ponziani; Giada Poli; Roberta Zini; Sergio Ferrari; Rossella Manfredini; Alberto Bosi; Alessandro M Vannucchi. (2007). MicroRNA expression profile in granulocytes from primary myelofibrosis patients.. EXPERIMENTAL HEMATOLOGY, vol. 35, pp. 1708-1718, ISSN:0301-472X
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Paola Guglielmelli; Alessandro Pancrazzi; Gaetano Bergamaschi; Vittorio Rosti; Laura Villani; Elisabetta Antonioli; Alberto Bosi; Giovanni Barosi; Alessandro M Vannucchi; (2007). Anaemia characterises patients with myelofibrosis harbouring Mpl mutation.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 137, pp. 244-247, ISSN:0007-1048
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Monica Bocchia; Alessandro M Vannucchi; Alessandro Gozzetti; Paola Guglielmelli; Giada Poli; Rosaria Crupi; Marzia Defina; Alberto Bosi; Lauria Francesco (2007). Insights into JAK2-V617F mutation in CML.. THE LANCET ONCOLOGY, vol. 8, pp. 864-866, ISSN:1470-2045
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Vannucchi AM; Barbui T (2007). Thrombocytosis and thrombosis. In: 49th Annual Meeting of the American Society of Hematology, pp. 363-369.
Ponziani V; Porfirio B; Guglielminelli P; Poli G; Guidi S; Nozzoli C; Lombardini L; Vannucchi AM; Bosi A. (2006). Development of a quantitative real time PCR assay for chimerism monitoring after sex-mismatched stem cell transplantation. Haematologica 91(s3) 2006, p. 20.. HAEMATOLOGICA, pp. 20-20, ISSN:0390-6078
A. MIGLIACCIO; A. VANNUCCHI; G. MIGLIACCIO; R. HOFFMAN (2006). MOLECULAR ADVANCES TOWARD THE UNDERSTANDING OF THE PATHO-BIOLOGY OF IDIOPATHIC MYELOFIBROSIS. CURRENT IMMUNOLOGY REVIEW, vol. 2, pp. 169-186, ISSN:1573-3955
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A. M. Vannucchi;P. Guglielmelli;E. Antonioli;S. Mappa;A. Pancrazzi;C. Bogani;V. Ponziani;A. Bosi (2006). Inconsistencies in the association between the JAK2(V617F) mutation and PRV-1 over-expression among the chronic myeloproliferative diseases.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 132, pp. 652-4; author reply 654, ISSN:0007-1048
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M. SANCHEZ; I. WEISSMAN; M. PALLAVICINI; M. VALERI; P. GUGLIELMELLI; G. MIGLIACCIO; A. VANNUCCHI; A. MIGLIACCIO (2006). Differential amplification of murine bipotent megakaryocytic/erythroid progenitor and precursor cells during recovery from acute and chronic erythroid stress. STEM CELLS, vol. 24, pp. 337-348, ISSN:1066-5099
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V. Ponziani;G. Gianfaldoni;F. Mannelli;F. Leoni;S. Ciolli;P. Guglielmelli;E. Antonioli;G. Longo;A. Bosi;A. M. Vannucchi (2006). The size of duplication does not add to the prognostic significance of FLT3 internal tandem duplication in acute myeloid leukemia patients.. LEUKEMIA, vol. 20, pp. 2074-2076, ISSN:0887-6924
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A. VANNUCCHI; A. PANCRAZZI; C. BOGANI; E. ANTONIOLI; P. GUGLIELMELLI (2006). A QUANTITATIVE ASSAY FOR JAK2V617F MUTATION IN MYELOPROLIFERATIVE DISORDERS BY ARMS-PCR AND CAPILLARY ELECTROPHORESIS. LEUKEMIA, vol. 20, pp. 1055-1060, ISSN:0887-6924
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Nozzoli C; Bartolozzi B; Guidi S; Orsi A; Vannucchi AM; Leoni F; Bosi A. (2006). Epstein-Barr virus-associated post-transplant lymphoproliferative disease with central nervous system involvement after unrelated allogeneic hematopoietic stem cell transplantation.. LEUKEMIA & LYMPHOMA, vol. 47(1), pp. 167-169, ISSN:1042-8194
Vannucchi, A.; Guglielmelli, P.; Antonioli, E.; Mappa, S.; Pancrazzi, A.; Bogani, C.; Ponziani, V.; Bosi, A. (2006). Inconsistencies in the association between the JAL2V617F mutation and PRV-1 over-expression among the chronic myeloproliferative diseases. BRITISH JOURNAL OF HAEMATOLOGY, vol. 132, pp. 651-654, ISSN:0007-1048
CELLAI C; LAURENZANA A; VANNUCCHI AM; CAPORALE R; PAGLIERANI M; DI LOLLO S; PANCRAZZI A; PAOLETTI F (2006). GROWTH INHIBITION AND DIFFERENTIATION OF HUMAN BREAST CANCER CELLS BY THE PAFR ANTAGONIST WEB-2086. BRITISH JOURNAL OF CANCER, vol. 94, pp. 1637-1642, ISSN:0007-0920
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Gianfaldoni, G; Antonioli, E; Mannelli, F; Vannucchi, Am; Bosi, A. (2005). Chronic relapsing thrombotic thrombocytopenic purpura successfully treated with rituximab: case report.. JOURNAL OF CHEMOTHERAPY, pp. 449-451, ISSN:1973-9478
Antonioli E; Guglielmelli P; Pancrazzi A; Bogani C; Verrucci M; Ponziani V; Longo G; Bosi A; Vannucchi AM. (2005). Clinical implications of the JAK2 V617F mutation in essential thrombocythemia.. LEUKEMIA, vol. 19(10), pp. 1847-1849, ISSN:0887-6924
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MARTELLI F.; GHINASSI B.; ALFANI E.; GATTA V.; PANETTA B.; PANCRAZZI A.; BOGANI C.; VANNUCCHI A.M.; F. PAOLETTI; MIGLIACCIO G.; MIGLIACCIO A.R. (2005). Variegation of the phenotype induced by the GATA-1low mutation in mice of different genetic backgrounds.. BLOOD, vol. 106, pp. 4102-4113, ISSN:0006-4971
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A. MIGLIACCIO; R. RANA; A. VANNUCCHI; F. MANZOLI (2005). ROLE OF GATA-1 IN NORMAL AND NEOPLASTIC HEMATOPOIESIS. In: Orkin SH. HEMATOPOIETIC STEM CELLS V, pp. 142-158, New York: KANZ L, WEISEL KC, ORLIC D, FIBBE WE.
A. M. Vannucchi;A. Pancrazzi;P. Guglielmelli;S. D. Lollo;C. Bogani;G. Baroni;L. Bianchi;A. R. Migliaccio;A. Bosi;F. Paoletti (2005). Abnormalities of GATA-1 in megakaryocytes from patients with idiopathic myelofibrosis.. THE AMERICAN JOURNAL OF PATHOLOGY, vol. 167, pp. 849-858, ISSN:0002-9440
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Vannucchi, ALESSANDRO MARIA; Ficarra, G.; Antonioli, E.; Bosi, Alberto (2005). Osteonecrosis of the jaw associated with zoledronate therapy in a patient with multiple myeloma.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 128, pp. 738-738, ISSN:0007-1048
E. ANTONIOLI; A. VANNUCCHI; A. BOSI; G. GIANFALDONI; F. MANNELLI (2005). Chronic relapsing thrombotic thrombocytopenic purpura succesfully treated with rituximab: case report. JOURNAL OF CHEMOTHERAPY, vol. 17, pp. 449-451, ISSN:1120-009X
AMABILE G; DI NOIA A; ALFANI E; A. VANNUCCHI; SANCHEZ M; BOSCO D; MIGLIACCIO AR; MIGLIACCIO G (2005). Isolation of TPO-dependent subclones from the multipotent 32D cell line. BLOOD CELLS, MOLECULES, & DISEASES, vol. 35, pp. 241-252, ISSN:1079-9796
A. Laurenzana; C. Cellai; A. Vannucchi; A. Pancrazzi; M. Romanelli; F. Paoletti (2005). WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential. LEUKEMIA, vol. 19, pp. 390-395, ISSN:0887-6924
A. VANNUCCHI; A. MIGLIACCIO; F. PAOLETTI; H. CHAGRAUOI; F. WENDLING (2005). Pathogenesis of myelofibrosis with myeloid metaplasia: lesson from mouse models of disease. SEMINARS IN ONCOLOGY, vol. 32, pp. 365-372, ISSN:0093-7754
VANNUCCHI AM.; BIANCHI L.; F. PAOLETTI; PANCRAZZI A.; TORRE E.; NISHIKAWA M.; ZINGARIELLO M.; DI BALDASSARRE A.; RANA RA.; LORENZINI R.; ALFANI E.; MIGLIACCIO G.; MIGLIACCIO AR. (2005). A pathobiological pathway linking thrombopoietin, GATA1 and TGFbeta1 in the development of myelofibrosis. BLOOD, vol. 105, pp. 3493-3501, ISSN:0006-4971
G.FICARRA; F.BENINATI; I.RUBINO; A.VANNUCCHI; G.LONGO; P. TONELLI; G.PINI PRATO (2005). Osteonecrosis of the jaws in periodontal patients with a history of biphosphonates treatment. JOURNAL OF CLINICAL PERIODONTOLOGY, vol. 32, pp. 1125-1128, ISSN:0303-6979
AM. Vannucchi; F.Martelli; A.Pancrazzi; P.Guglielmelli; F.Almerigogna; M.Valeri; E.Alfani; G.Migliaccio; AR. Migliaccio. (2005). Splenectomy favours development of extramedullary hematopoiesis in the GATA-1low model of myelofibrosis.. BLOOD, vol. 106, pp. 3513-3513, ISSN:0006-4971
MIGLIACCIO AR; RANA RA; A. VANNUCCHI; MANZOLI FA (2005). Role of GATA-1 in normal and neoplastic hemopoiesis. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 1044, pp. 142-158, ISSN:0077-8923, New York Academy of Sciences:Subscription Services Department, 2 East 63rd Street:New York, NY 10021:(800)843-6927, (212)838-0230, EMAIL: publications@nyas.org, INTERNET: http://www.nyas.org, Fax: (212)888-2894:
CENTURIONE L; DI BALDASSARRE A; ZINGARIELLO M; BOSCO D; GATTA V; RANA RA; LANGELLA V; DI VIRGILIO A; A. VANNUCCHI; MIGLIACCIO AR (2004). Increased and pathological emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1low mice. BLOOD, vol. 104, pp. 3573-3580, ISSN:0006-4971
A. M. Vannucchi;A. Grossi;A. Pancrazzi;E. Antonioli;P. Guglielmelli;F. Balestri;M. Biscardi;S. Bulgarelli;G. Longo;C. Graziano;L. Gugliotta;A. Bosi (2004). PRV-1, erythroid colonies and platelet Mpl are unrelated to thrombosis in essential thrombocythaemia.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 127, pp. 214-219, ISSN:0007-1048
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CIOLLI S; A. VANNUCCHI; LEONI F; NOZZOLI C; LONGO G; SALATI A; PANCRAZZI A; BIANCHI L; BOSI A; ROSSI FERRINI P. (2004). Internal tandem duplication of FLT3 gene (FLT3/TID) predicts a poor post-remission outcome in adult patients witha cute non-promyelocytic leukemia. LEUKEMIA & LYMPHOMA, vol. 45, pp. 73-78, ISSN:1042-8194
A. VANNUCCHI; L. BIANCHI ; F. PAOLETTI; V. DI GIACOMO; G. MIGLIACCIO; A.R.MIGLIACCIO (2004). Impaired GATA-1 expression and myelofibrosis in an animal model. PATHOLOGIE BIOLOGIE, vol. 52, pp. 275-279, ISSN:0369-8114
A. M. Vannucchi;A. Grossi;A. Pancrazzi;E. Antonioli;P. Guglielmelli;F. Balestri;M. Biscardi;S. Bulgarelli;G. Longo;C. Graziano;L. Gugliotta;A. Bosi (2004). PRV-1, erythroid colonies and platelet Mpl are unrelated to thrombosis in essential thrombocythaemia.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 127, pp. 214-219, ISSN:0007-1048
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A. MIGLIACCIO; R. LORENZINI; A. VANNUCCHI; G. MIGLIACCIO; G. SPANGRUDE (2003). Robust levels of long term multilineage reconstitution in the absence of stem cell self-replication in W/Wv mice transplanted with purified stem cells. JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, vol. 12, pp. 409-424, ISSN:1525-8165
A. VANNUCCHI; A. MIGLIACCIO (2003). Little steps toward the identification of the myelofibrotic locus. BLOOD, vol. 101, pp. 5088-5089, ISSN:0006-4971
A. MIGLIACCIO; R. RANA; R. LORENZINI; L. BIANCHI; A. VANNUCCHI;G. MIGLIACCIO; M. SANCHEZ; L. CENTURIONE; S. ORKIN (2003). GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant.. JOURNAL OF EXPERIMENTAL MEDICINE, vol. 197, pp. 281-296, ISSN:0022-1007
F. PAOLETTI; A. VANNUCCHI; L. BIANCHI; N. DELLA MALVA; C. CELLAI; A. LAURENZANA (2002). Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells. THE FASEB JOURNAL, vol. 16, pp. 733-735, ISSN:0892-6638
Bosi A; Bartolozzi B; Vannucchi AM; Orsi A; Guidi S; Rossi Ferrini P. (2002). Polymerase chain reaction-based "pre-emptive" therapy with cidofovir for cytomegalovirus reactivation in allogeneic hematopoietic stem cells transplantation recipients: a prospective study.. HAEMATOLOGICA, vol. 87(4), pp. 446-447, ISSN:0390-6078
A. VANNUCCHI; L. BIANCHI; C. CELLAI; F. PAOLETTI; R. RANA; R. LORENZINI; G. MIGLIACCIO; A. MIGLIACCIO (2002). DEVELOPMENT OF MYELOFIBROSIS IN MICE GENETICALLY IMPAIRED FOR GATA-1 EXPRESSION (GATA-1LOW) MICE.. BLOOD, vol. 100, pp. 1123-1132, ISSN:0006-4971
A. VANNUCCHI; L. BIANCHI; C. CELLAI; F. PAOLETTI; V. CARRAI; A. CALZOLARI; L. CENTURIONE; R. LORENZINI; C. CARTA; E. ALFANI; M. SANCHEZ; G. MIGLIACCIO; A. MIGLIACCIO (2001). Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their Gata-1 expressione (GATA-1low mice).. BLOOD, vol. 97, pp. 3040-3050, ISSN:0006-4971
A. VANNUCCHI; GLINZ S; BOSI A; CAPORALE R; ROSSI FERRINI P (2001). Selective ex vivo expansion of cytomegalovirus/specific CD4 and CD8 T lymphocytes using dendritic cells pulsed with a human leukocyte antigen A201 restricted peptide. BRITISH JOURNAL OF HAEMATOLOGY, vol. 113, pp. 479-482, ISSN:0007-1048
A. VANNUCCHI; F. PAOLETTI; C. CELLAI; R. CAPORALE; M. SANCHEZ; S. LINARI; P. ROSSI FERRINI; G. MIGLIACCIO; A. MIGLIACCIO (2000). Identification and characterization of a bipotent (eryhtroid and megakaryocytic) cell precursor from the spleen of phenylhydrazine-treated mice.. BLOOD, vol. 95, pp. 2559-2568, ISSN:0006-4971
A. Bosi; D. Laszlo; S. Bacci; R. Fanci; S. Guidi; R. Saccardi; A. M. Vannucchi; P. Rossi-Ferrini (1999). An open evaluation of triple antibiotic therapy including vancomycin for febrile bone marrow transplant recipients with severe neutropenia.. JOURNAL OF CHEMOTHERAPY, vol. 11, pp. 287-292, ISSN:1120-009X
A. M. Vannucchi; S. Glinz; A. Bosi; C. Fallai; P. Rossi-Ferrini (1999). Detection of contaminating tumor cells by RT-PCR in breast cancer patients.. BONE MARROW TRANSPLANTATION, vol. 24, pp. 228-229, ISSN:0268-3369
C. Cellai; R. Matucci; A. M. Vannucchi; F. Paoletti (1999). Constitutive muscarinic receptors are involved in the growth and differentiation of friend erythroleukemia cells.. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 178, pp. 333-340, ISSN:0021-9541
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A. VANNUCCHI; LINARI S.; LIN C-S.; KOURY M.J.; BONDURANT M.C.; MIGLIACCIO A.R. (1999). Increased expression of the distal, but not of the proximal, Gata1 transcripts during differentiation of primary erythroid cells.. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 180, pp. 390-401, ISSN:0021-9541, John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551:
Rossi Ferrini P; Grossi A; Vannucchi AM; Barosi G; Guarnone R; Piva N; Musto P; Balleari E (1998). A randomized double-blind placebo-controlled study with subcutaneous recombinant human erythropoietin in patients with low-risk myelodysplastic syndromes.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 103, pp. 1070-1074, ISSN:1365-2141
GROSSI A.; A. VANNUCCHI; BACCI P.; CAPORALE R.; CAPPELLI G.; VISCONTI G.; PAGLIAI G.; FERRINI PR. (1998). Erythropoietin upregulates the expression of its own receptor in TF-1 cell line. LEUKEMIA RESEARCH, vol. 22(2), pp. 145-151, ISSN:0145-2126, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:
A. Bosi; M. Zazzi; A. Amantini; M. Cellerini; A. M. Vannucchi; A. De Milito; S. Guidi; R. Saccardi; L. Lombardini; D. Laszlo; P. Rossi Ferrini (1998). Fatal herpesvirus 6 encephalitis after unrelated bone marrow transplant.. BONE MARROW TRANSPLANTATION, vol. 22, pp. 285-288, ISSN:0268-3369
A. M. Vannucchi; A. Bosi; S. Glinz; P. Pacini; S. Linari; R. Saccardi; R. Alterini; L. Rigacci; S. Guidi; L. Lombardini; G. Longo; M. P. Mariani; P. Rossi-Ferrini (1998). Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RT-PCR for cytokeratin-19 mRNA.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 103, pp. 610-617, ISSN:0007-1048
S. Linari; A. M. Vannucchi; S. Ciolli; F. Leoni; R. Caporale; A. Grossi; G. Pagliai; V. Santini; F. Paoletti; P. R. Ferrini (1998). Coexpression of erythroid and megakaryocytic genes in acute erythroblastic (FAB M6) and megakaryoblastic (FAB M7) leukaemias.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 102, pp. 1335-1337, ISSN:0007-1048
A. VANNUCCHI; LINARI S.; CELLAI C.; KOURY M.J.; PAOLETTI F. (1997). Constitutive and inducible expression of megakaryocyte-specific genes in Friend erythroleukaemia cells.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 99, pp. 500-508, ISSN:0007-1048
A. M. Vannucchi; A. Bosi; S. Linari; S. Guidi; G. Longo; L. Lombardini; M. P. Mariani; R. Saccardi; D. Laszlo; P. Rossi Ferrini (1997). High doses of recombinant human erythropoietin fail to accelerate platelet reconstitution in allogeneic bone marrow transplantation. Results of a pilot study.. HAEMATOLOGICA, vol. 82, pp. 53-56, ISSN:0390-6078
G. Longo; E. Filimberti; S. Cinotti; A. M. Vannucchi; L. Lombardini; P. R. Ferrini (1997). Pretransplant factor XII levels correlate with prognosis in patients undergoing autologous graft for hematological malignancies.. HAEMATOLOGICA, vol. 82, pp. 360-361, ISSN:0390-6078
D. Laszlo; S. Bacci; A. Bosi; R. Fanci; S. Guidi; R. Saccardi; A. M. Vannucchi; P. Rossi Ferrini (1997). Randomized trial comparing netilmicin plus imipenem-cilastatin versus netilmicin plus ceftazidime as empiric therapy for febrile neutropenic bone marrow transplant recipients.. JOURNAL OF CHEMOTHERAPY, vol. 9, pp. 95-101, ISSN:1120-009X
ASHIHARA E.; A. VANNUCCHI; MIGLIACCIO G.; MIGLIACCIO A.R. (1997). Growth factor receptor expression during in vitro differentiation of partially purified populations containing murine stem cells.. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 171(3), pp. 343-356, ISSN:0021-9541, John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551:
BONSI L.; GROSSI A.; STRIPPOLI P.; TUMIETTO F.; TONELLI R.; A. VANNUCCHI; RONCHI A.; OTTOLENGHI S.; VISCONTI G.; AVANZI G.C.; PEGORARO L.; BAGNARA G.P. (1997). An erythroid and megakaryocytic common precursor cell line (B1647) expressing both c-mpl and erythropoietin receptor (Epo-R) proliferates and modifies globin chain synthesis in response to megakaryocyte growth and development factor (MGDF) but not to erythropoietin (Epo).. BRITISH JOURNAL OF HAEMATOLOGY, vol. 98(3), pp. 549-559, ISSN:0007-1048, Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205:
F. Paoletti; A. Mocali; C. Cellai; R. Caporale; A. M. Vannucchi (1996). Megakaryocyte-like increase in ploidy of Friend's erythroleukemia cells induced to endoreplication by colcemid.. EXPERIMENTAL HEMATOLOGY, vol. 24, pp. 1441-1448, ISSN:0301-472X
A. R. Migliaccio; A. M. Vannucchi; G. Migliaccio (1996). Molecular control of erythroid differentiation.. INTERNATIONAL JOURNAL OF HEMATOLOGY, vol. 64, pp. 1-29, ISSN:0925-5710
V. Santini; A. Zoccolante; A. Bosi; S. Guidi; R. Saccardi; A. M. Vannucchi; G. Martinazzo; P. A. Bernabei; P. R. Ferrini (1996). Detection of bcr/abl transcripts by RT-PCR and their colorimetric evaluation in chronic myeloid leukemia patients receiving allogeneic bone marrow transplantation.. HAEMATOLOGICA, vol. 81, pp. 201-207, ISSN:0390-6078
A. M. Vannucchi; A. Bosi; A. Ieri; S. Guidi; R. Saccardi; L. Lombardini; S. Linari; D. Laszlo; G. Longo; P. Rossi-Ferrini (1996). Combination therapy with G-CSF and erythropoietin after autologous bone marrow transplantation for lymphoid malignancies: a randomized trial.. BONE MARROW TRANSPLANTATION, vol. 17, pp. 527-531, ISSN:0268-3369
F. PAOLETTI; A. VANNUCCHI; A. MOCALI; R. CAPORALE; S. BURSTEIN (1995). Identification and conditions for selective expression of megakaryocytic markers in Friend erythroleukemia cells. BLOOD, vol. 86, pp. 2624-2631, ISSN:0006-4971
D.Laszlo ; A. Bosi ; S. Guidi ; R. Saccardi R; A. M .Vannucchi ; L.Lombardini;G. Longo ; R.Fanci ; A. Azzi ;R. De Santis ; PL . Rossi Ferrini. (1995). Prostaglandin E2 bladder instillation for the treatment of hemorrhagic cystitis after allogeneic bone marrow transplantation.. HAEMATOLOGICA, vol. 80 (5), pp. 421-425, ISSN:0390-6078
GROSSI A.; A. VANNUCCHI; BACCI P.; LONGO G.; RAFANELLI D.; ALTERINI R.; ROSSI FERRINI P. (1995). In vivo administration of stem cell factor enhances both proliferation and maturation of murine megakaryocytes.. HAEMATOLOGICA, vol. 80(1), pp. 18-24, ISSN:0390-6078, Fondaz Ferrata Storti:Strada Nuova 134, 27100 Pavia Italy:011 39 0382 531182, EMAIL: office@haematologica.it, Fax: 011 39 0382 27721:
A. M. Vannucchi; A. Bosi; L. Lombardini; A. Grossi; P. Bacci; S. Guidi; R. Saccardi; P. Rossi-Ferrini (1995). Circulating CFU-E during hematopoietic recovery after allogeneic bone marrow transplantation: relationship to erythroid engraftment.. EXPERIMENTAL HEMATOLOGY, vol. 23, pp. 1337-1340, ISSN:0301-472X
A. M. Vannucchi; A. Bosi; D. Laszlo; S. Guidi; R. Saccardi; P. Rossi-Ferrini (1995). Treatment of a delayed graft failure after allogeneic bone marrow transplantation with IL-3 and GM-CSF.. HAEMATOLOGICA, vol. 80, pp. 341-343, ISSN:0390-6078
A. Azzi; R. Fanci; A. Bosi; S. Ciappi; K. Zakrzewska; R. de Santis; D. Laszlo; S. Guidi; R. Saccardi; A. M. Vannucchi (1994). Monitoring of polyomavirus BK viruria in bone marrow transplantation patients by DNA hybridization assay and by polymerase chain reaction: an approach to assess the relationship between BK viruria and hemorrhagic cystitis.. BONE MARROW TRANSPLANTATION, vol. 14, pp. 235-240, ISSN:0268-3369
A. M. Vannucchi; A. Bost; A. Grossi; S. Guidi; R. Saccardi; P. Rossi-Ferrini (1994). Down-modulation of serum erythropoietin levels following cyclosporin A infusion.. BONE MARROW TRANSPLANTATION, vol. 13, pp. 497-498, ISSN:0268-3369
A. VANNUCCHI; PAOLETTI F.; GROSSI A. (1994). A common megakaryocytic and erythrocytic precursor in murine erythroleukemia (Friend) cells?. EXPERIMENTAL HEMATOLOGY, vol. 22(2), pp. 110-110, ISSN:0301-472X, Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680:
A. M. Vannucchi; D. Rafanelli; G. Longo; A. Bosi; S. Guidi; R. Saccardi; E. Filimberti; S. Cinotti; A. Grossi; M. Morfini (1994). Early hemostatic alterations following bone marrow transplantation: a prospective study.. HAEMATOLOGICA, vol. 79, pp. 519-525, ISSN:0390-6078
P.L. Rossi Ferrini; A.M.Vannucchi (1994). Terapia con eritropoietina dopo trapianto di midollo osseo. In: C. Bernasconi. Citochine emopoietiche: Impiego clinico, pp. 115-121, Pavia: Edizioni Medico-Scientifiche Pavia.
A. M. Vannucchi; A. Grossi; D. Rafanelli; M. Statello; S. Cinotti; P. Rossi-Ferrini (1994). Inhibition of erythropoietin production in vitro by human interferon gamma.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 87, pp. 18-23, ISSN:0007-1048
S. Porciani; A. Becciolini; A. Lanini; M. Storto; R. Saccardi; A. Bosi; S. Guidi; A.M. Vannucchi; L. Lombardini (1994). Erythrocyte polyamines in the monitoring of bone marrow transplantation.. In: Convegno, vol. Int. J. Biol. Markers vol. 9, pp. 160-160.
P. Rossi Ferrini; A.M. Vannucchi (1994). Malattie dell'emostasi e della trombosi. di W.E. Hathaway, S.H. Goodnight, Milano: Mc-Graw Hill, 883862240X.
S. Porciani; A. Lanini; P. Comeglio; A. Tani; R. Saccardi; A. Bosi; S. Guidi; A.M. Vannucchi; A. Becciolini (1993). Significance of erythrocyte polyamines in bone marrow transplantation.. THE INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, vol. Int. J. Biol. Markers vol. 8, pp. 46-47, ISSN:0393-6155
A. Grossi; A.M. Vannucchi; D. Rafanelli; P.L. Rossi Ferrini (1993). The humoral regulation of normal and pathological erythropoieisis. In: P.P. Foà. Humoral factors in the regulation of tissue growth, pp. 47-70, New York: Sringer-Verlag, ISBN:0387978798.
A. Bosi; S. Guidi; A. Messori; R. Saccardi; L. Lombardini; A. M. Vannucchi; R. Fanci; P. Rossi-Ferrini (1993). Ondansetron versus chlorpromazine for preventing emesis in bone marrow transplant recipients: a double-blind randomized study.. JOURNAL OF CHEMOTHERAPY, vol. 5, pp. 191-196, ISSN:1120-009X
Rossi Ferrini P; Santini V; Ciolli S; Grossi A; Leoni F; Rafanelli D; Vannucchi AM. (1993). The role of haematopoietic growth factors in the treatment of myelodysplastic syndromes.. HEMATOLOGICAL ONCOLOGY, vol. 11, pp. 32-35, ISSN:0278-0232
A. M. Vannucchi; A. Bosi; A. Grossi; S. Guidi; R. Saccardi; P. Bacci; L. Lombardini; P. Rossi-Ferrini (1993). The use of erythropoietin in the treatment of post-bone marrow transplantation anemia.. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol. 16 Suppl 5, pp. 8-12, ISSN:0391-3988
A. M. Vannucchi; A. Grossi; A. Bosi; D. Rafanelli; M. Statello; S. Guidi; R. Saccardi; P. Rossi-Ferrini (1993). Effects of cyclosporin A on erythropoietin production by the human Hep3B hepatoma cell line.. BLOOD, vol. 82, pp. 978-984, ISSN:0006-4971
A. Bosi; R. Fanci; P. Pecile; S. Guidi; R. Saccardi; A. M. Vannucchi; G. Longo; E. Donnini; A. Orsi; P. Rossi-Ferrini (1992). Aztreonam versus colistin-neomycin for selective decontamination of the digestive tract in patients undergoing bone marrow transplantation: a randomized study.. JOURNAL OF CHEMOTHERAPY, vol. 4, pp. 30-34, ISSN:1120-009X
D. Rafanelli; A. Grossi; G. Longo; A. M. Vannucchi; P. Bacci; P. R. Ferrini (1992). Recombinant human erythropoietin for treatment of myelodysplastic syndromes.. LEUKEMIA, vol. 6, pp. 323-327, ISSN:0887-6924
A. Messori; A. Bosi; S. Guidi; G. Longo; C. Pistolesi; R. Saccardi; T. Valenza; A. M. Vannucchi (1992). PKRD: a pharmacokinetic program for least-squares and bayesian analysis of repeated-dose pharmacokinetic curves.. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, vol. 38, pp. 27-35, ISSN:0169-2607
F. PAOLETTI; MOCALI A.; VANNUCCHI A.M. (1992). Acetylcholinesterase in murine erythroleukemia (Friend) cells: evidence for megakaryocyte-like expression and potential growt-regulatory role of enzyme activity. BLOOD, vol. 79, pp. 2873-2879, ISSN:0006-4971
P. Bacci; A. Grossi; A. M. Vannucchi; D. Rafanelli; A. Casini; M. De Luca (1992). Effects of miocamycin and erythromycin on polymorphonuclear cell function.. JOURNAL OF CHEMOTHERAPY, vol. 4, pp. 268-270, ISSN:1120-009X
A. M. Vannucchi; A. Bosi; A. Grossi; S. Guidi; R. Saccardi; L. Lombardini; P. Rossi-Ferrini (1992). Stimulation of erythroid engraftment by recombinant human erythropoietin in ABO-compatible, HLA-identical, allogeneic bone marrow transplant patients.. LEUKEMIA, vol. 6, pp. 215-219, ISSN:0887-6924
A. VANNUCCHI; GROSSI A.; PAOLETTI F.; RAFANELLI D.; BACCI P.; FERRINI P.R. (1992). Constitutive expression of a megakaryocytic functional property by murine erythroleukemia (Friend) cells: the incorporation of serotonin.. EXPERIMENTAL HEMATOLOGY, vol. 20, pp. 1296-1301, ISSN:0301-472X
A. Grossi; A. M. Vannucchi; G. Longo; D. Rafanelli; P. Rossi Ferrini (1991). [Essential thrombocythemia: conventional therapy]. HAEMATOLOGICA, vol. 76 Suppl 3, pp. 368-370, ISSN:0390-6078
A. M. Vannucchi; A. Grossi; A. Bosi; D. Rafanelli; S. Guidi; R. Saccardi; R. Alterini; P. R. Ferrini (1991). Impaired erythropoietin production in mice treated with cyclosporin A.. BLOOD, vol. 78, pp. 1615-1618, ISSN:0006-4971
A. Bosi; A. M. Vannucchi; A. Grossi; S. Guidi; R. Saccardi; D. Rafanelli; G. Longo; P. R. Ferrini (1991). Inadequate erythropoietin production in allogeneic bone marrow transplant patients.. HAEMATOLOGICA, vol. 76(4), pp. 280-284, ISSN:0390-6078
J. H. Amuasi; P. Ferri; A. Grossi; L. Vannucchi; A. M. Vannucchi; P. R. Ferrini (1991). Quantitative platelet imaging and comparison of four mathematical models for the evaluation of platelet mean life span in patients with chronic immune thrombocytopenia.. HAEMATOLOGICA, vol. 76, pp. 104-108, ISSN:0390-6078
A. Bosi; A. M. Vannucchi; A. Grossi; S. Guidi; D. Rafanelli; R. Saccardi; P. R. Ferrini (1991). Serum erythropoietin levels in allogeneic, non T-depleted bone marrow transplantation, and the effects of rhEpo administration.. BONE MARROW TRANSPLANTATION, vol. 7 Suppl 2, pp. 87-87, ISSN:0268-3369
A. Bosi; A. M. Vannucchi; A. Grossi; S. Guidi; L. Vannucchi; R. Saccardi; P. A. Bernabei; G. Longo; D. Rafanelli; P. Rossi-Ferrini (1991). Serum erythropoietin levels in patients undergoing autologous bone marrow transplantation.. BONE MARROW TRANSPLANTATION, vol. 7, pp. 421-425, ISSN:0268-3369
A. M. Vannucchi; G. Longo; A. Bosi; S. Cinotti; E. Filimberti; S. Guidi; R. Saccardi; M. Morfini; E. Boni; P. Rossi Ferrini (1991). Early haemostatic modifications following cryopreserved graft infusion.. BONE MARROW TRANSPLANTATION, vol. 8, pp. 171-176, ISSN:0268-3369
D. Rafanelli; A. Grossi; A. M. Vannucchi; S. Cinotti; M. Morfini; P. R. Ferrini (1990). The effect of picotamide on platelet function in patients with myeloproliferative disorders.. THROMBOSIS AND HAEMOSTASIS, vol. 63, pp. 525-526, ISSN:0340-6245
A. Bosi; E. De Majo; S. Guidi; F. Parri; R. Saccardi; A. M. Vannucchi; R. Fanci; P. R. Ferrini (1990). Kinetics of anti-CMV antibodies after administration of intravenous immunoglobulins to bone marrow transplant recipients.. HAEMATOLOGICA, vol. 75, pp. 109-112, ISSN:0390-6078
A. VANNUCCHI; GROSSI A.; RAFANELLI D.; FERRINI P.R. (1990). In vivo stimulation of megakaryocytopoiesis by recombinant murine granulocyte-macrophage colony-stimulating factor.. BLOOD, vol. 76(8), pp. 1473-1480, ISSN:0006-4971, American Society of Hematology:1900 M Street Northwest, Suite 200:Washington, DC 20036:(800)633-4931, (202)776-0544, EMAIL: publishing@hematology.org, ash@hematology.org, INTERNET: http://www.hematology.org, Fax: (202)776-0551:
Vannucchi AM; Grossi A; Rafanelli D; Vannucchi L; Rossi Ferrini P. (1990). Binding of recombinant human 125I-erythropoietin to CFU-E from the spleen of anemic mice.. HAEMATOLOGICA, vol. 75(1), pp. 21-26, ISSN:0390-6078
Kimmel M; Grossi A; Amuasi J; Vannucchi AM. (1990). Non-parametric analysis of platelet lifespan.. CELL AND TISSUE KINETICS, vol. 23(3), pp. 191-202, ISSN:0008-8730
GROSSI A.; A. VANNUCCHI; ROSSI FERRINI P. (1990). Humoral regulation of megakaryocytopoiesis.. BIOTHERAPY, vol. 2(4), pp. 375-385, ISSN:0921-299X, Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254:
P. Rossi Ferrini; A. Grossi; V. Santini; A. M. Vannucchi (1989). [GM-CSF: its clinical administration; the treatment of aplasia]. HAEMATOLOGICA, vol. 74, pp. 489-500, ISSN:0390-6078
GROSSI A.; A. VANNUCCHI; RAFANELLI D.; ROSSI FERRINI P. (1989). Recombinant human erythropoietin has little influence on megakaryocytopoiesis in mice.. BRITISH JOURNAL OF HAEMATOLOGY, vol. 71(4), pp. 463-468, ISSN:0007-1048, Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205:
A. M. Vannucchi; A. Grossi; D. Rafanelli; L. Vannucchi; P. R. Ferrini (1989). A dot assay for the erythropoietin receptor using human recombinant 125I-erythropoietin.. ANALYTICAL BIOCHEMISTRY, vol. 182, pp. 182-186, ISSN:0003-2697
A. VANNUCCHI; GROSSI A.; RAFANELLI D.; VANNUCCHI L.; FERRINI P.R. (1988). Serotonin incorporation as a marker of murine megakaryocyte proliferation in liquid cultures.. EXPERIMENTAL HEMATOLOGY, vol. 16(11), pp. 916-921, ISSN:0301-472X, Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680:
A. M. Vannucchi; A. Grossi; D. Rafanelli; P. Rossi Ferrini; G. Ramponi (1988). Partial purification and biochemical characterization of human plasma thrombopoietin.. LEUKEMIA, vol. 2, pp. 236-240, ISSN:0887-6924
A. Grossi; S. Rosseti; A. M. Vannucchi; D. Rafanelli; P. R. Ferrini (1988). Occurrence of haemorrhagic and thrombotic events in myeloproliferative disorders: a retrospective study of 108 patients.. CLINICAL AND LABORATORY HAEMATOLOGY, vol. 10, pp. 167-175, ISSN:0141-9854
GROSSI A.; A. VANNUCCHI; RAFANELLI D.; VANNUCCHI L.; FERRINI P.R. (1987). Megakaryocyte progenitors in the bone marrow and peripheral blood of patients with myeloproliferative diseases.. AMERICAN JOURNAL OF HEMATOLOGY, vol. 25(4), pp. 371-376, ISSN:0361-8609, John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551:
A. Grossi; A. M. Vannucchi; D. Rafanelli; P. R. Ferrini (1987). Biological characterization of partially purified human urinary thrombopoietin.. HAEMATOLOGICA, vol. 72, pp. 291-295, ISSN:0390-6078
A.M. Vannucchi; A. grossi; D. Rafanelli; S. Di Lollo; C. Bertani; P.L. Rossi Ferrini (1986). Partial purification of thrombopoietic stimulating activity from human urine. In: R.R. Levine, N. Williams, J. Levin, B.L. Evatt. Megakayocyte development and function, pp. 221-226, New York: Alan R. Liss, Inc, ISBN:0845150650.
GROSSI A.; A. VANNUCCHI; RAFANELLI D.; FILIMBERTI E.; ROSSI FERRINI P. (1986). Beta-thromboglobulin content in megakaryocytes of patients with myeloproliferative diseases.. THROMBOSIS RESEARCH, vol. 43(3), pp. 367-374, ISSN:0049-3848, Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010:
A. Grossi; A. M. Vannucchi; P. Casprini; M. Morfini; P. R. Ferrini (1986). Effects of high-dose intravenous gammaglobulin on kinetic parameters of 51Cr-labelled platelets in chronic ITP.. HAEMATOLOGICA, vol. 71, pp. 123-127, ISSN:0390-6078
A. M. Vannucchi; A. Grossi; D. Rafanelli; S. DiLollo; C. Bertani; P. RossiFerrini (1986). Partial purification of a thrombopoietic stimulating activity from human urine.. PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH, vol. 215, pp. 221-225, ISSN:0361-7742
GROSSI A.; A. VANNUCCHI; RAFANELLI D.; FERRINI P.R. (1985). Megakaryocyte enrichment procedures.. BLOOD, vol. 65(2), pp. 506-507, ISSN:0006-4971, American Society of Hematology:1900 M Street Northwest, Suite 200:Washington, DC 20036:(800)633-4931, (202)776-0544, EMAIL: publishing@hematology.org, ash@hematology.org, INTERNET: http://www.hematology.org, Fax: (202)776-0551:
M. Morfini; A. M. Vannucchi; A. Grossi; S. Cinotti; D. Rafanelli; P. R. Ferrini (1985). Direct evidence that high dose intravenous gammaglobulin blocks splenic and hepatic sequestration of 51Cr-labeled platelets in ITP.. THROMBOSIS AND HAEMOSTASIS, vol. 54, pp. 554-554, ISSN:0340-6245
A. Grossi; A. M. Vannucchi; D. Rafanelli; P. Rossi Ferrini (1984). Transient remission of chronic idiopathic thrombocytopenic purpura during septic abscess and pneumothorax.. HAEMATOLOGICA, vol. 69, pp. 572-575, ISSN:0390-6078
G. Longo; F. Cecchi; A. Grossi; M. Matucci; D. Rafanelli; A. M. Vannucchi; P. Casprini; S. Vannini; M. Morfini; A. Dolara (1984). Coagulation and platelet function in hypertrophic cardiomyopathy.. THROMBOSIS AND HAEMOSTASIS, vol. 51, pp. 299-299, ISSN:0340-6245
A. Grossi; A. M. Vannucchi; P. Casprini; S. Guidi; D. Rafanelli; M. G. Pecchioli; P. Rossi Ferrini (1983). Different patterns of platelet turnover in chronic idiopathic thrombocytopenic purpura.. SCANDINAVIAN JOURNAL OF HAEMATOLOGY, vol. 31, pp. 206-214, ISSN:0036-553X