Personale

Recapiti

Orario di ricevimento

Italiano

Biografia

Curriculum

Interessi

Note

Pubblicazioni

Insegnamenti

English

Biography

Curriculum

Interest

Note

Nicoletta GALEOTTI

Ruolo attuale:: Professore Associato
SSD:: BIOS-11/A - Farmacologia
Afferenza organizzativa:: Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)

Recapiti

	0552758391
	nicoletta.galeotti(AT)unifi.it

Nicoletta GALEOTTI

Orario di ricevimento (aggiornato al 01/03/2025)

tutti i giorni previo appuntamento.
Tel: 055 2758391
e-mail: nicoletta.galeotti@unifi.it

Nicoletta GALEOTTI

Biografia

1989: Laurea in Farmacia, Università di Pisa

1993: Specializzazione in Farmacologia Sperimentale, Università di Firenze

1999: Dottorato in Farmacologia e Tossicilogia, Università di Firenze

Nicoletta GALEOTTI

Curriculum

Titoli accademici

2000: Corso sulle nuove prospettive per la terapia delle cefalee

1999: Dottorato di Ricerca in Farmacologia e Tossicologia

1995: Corso di Perfezionamento sulle biotecnologie applicate allo studio delle proteine G eterotrimeriche

1993: Specializzazione in Farmacologia, 70 e lode

1989: Laurea in Farmacia, 110 e lode

Esperienze professionali

2015: Professore Associato, Università di Firenze

2000-2015: Ricercatore, Università di Firenze

1998-1999: ricercatore Price Foundation, Washington DC, USA, presso Dipartimento di Biologia Cellulare, Università degli Studi di Pisa,

1992-1994: assegnista di ricerca presso l'Università di Firenze

Incarichi Istituzionali:

2024: Coordinatore Sezione Farmacologia e Tossicologia, Dipartimento Neurofarba

2023: Membro del Comitato di Gestione Centro di Ricerca AGE-Florence

2022: Membro del Consiglio Direttivo del Centro per le Biotecnologie di Interesse Agrario, Chimico e Industriale (CIBIACI)

2012 ad oggi: membro del Collegio dei docenti dottorato Area del Farmaco e Trattamenti Innovativi

2005-2011: membro del Collegio dei Docenti dottorato Farmacologia e Tossicologia

2004 ad oggi: Membro del Comitato Scientifico Dipartimento Neurofarba

Attività didattica

2024 ad oggi: Farmacologia Generale, CdS in CTF

2000 ad oggi: Farmacognosia, CdS in CTF e SFA

2001: Farmacologia presso la Facoltà di Farmacia, Università di Odensa, Danimarca

2003-2004: corsi ECM per gli Ordini Professionali dei Farmacisti

2004-2005: Farmacologia e Farmacoterapia, Scuola di Specializzazione in Farmacia Ospedaliera; Farmacognosia per il corso di perfezionamento TEO

2019 ad oggi: Fitoterapia del dolore: Master di I e II livello in Fitoterapia

Attività editoriale

2023:Frontiers in Pharmaacology, membro del Comitato Editoriale

2022: Biomedicines, Special Issue Guest Editor

2021: Biomedicine, membro del comitato editoriale

2020: Neuropharmacology, membro del Comitato Editoriale

2017: EC Psychology and Psychiatry, membro del comitato editoriale

2015: SM Journal of Depression Research and Treatment, membro del comitato editoriale

2014: traduzione e revisione di “Fundamentals of Pharmacognosy and Phytotherapy”, seconda edizione, di Heinrich, Barnes, Gibbons, Williamson, Ed. Churchill Livingstone

2013: Pharmacognosy Journal (Elsevier), membro del comitato editoriale

2006: revisore farmacologico per monografie ESCOP

Premi e riconoscimenti:

2000: Premio Aventis

1999: premio Ricerca Farmacologica Maurizio Soma

1993-1999: borse di viaggio della Società Italiana di Farmacologia; relatore invitato

1993: premio di ricerca da LPB

1992: premio di ricerca da Fidia Spa

Nicoletta GALEOTTI

Interessi

Indagine sulle basi molecolari e cellulari della neuroinfiammazione microglia-mediata
Studio della senescenza cellulare e invecchiamento
Indagine sulle alterazioni epigenetiche e molecolari nel dolore neuropatico di origine centrale e periferica mirata all'identificazione di terapie innovative
Strategia antisenso applicata alle patologie neurodegenerative
Studio del fenotipo comportamentale indotto da composti naturali nel dolore neuropatico e nei disturbi neurodegenerativi
Indagine sulle vie di comunicazione neurone-glia nella demielinizzazione e nella neurodegenerazione

Nicoletta GALEOTTI

Note

Tematiche di tesi

- indagine su composti naturali in grado di promuovere attività analgesica e neurorigenerativa

- studio delle vie di comunicazione neurone-glia nella demielinizzazione e neurodegenerazione

- ruolo patologico della senescenza microgliale nei disturbi neurodegenerativi

- identificazione di terapia innovative anti-senescenza

- strategia antisenso applicata ai disturbi neurodegenerativi con sviluppo di dolore neuropatico

Nicoletta GALEOTTI

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Videtta, Giacomina; Sasia, Chiara; Galeotti, Nicoletta (2025). High Rosmarinic Acid Content Melissa officinalis L. Phytocomplex Modulates Microglia Neuroinflammation Induced by High Glucose. ANTIOXIDANTS, vol. 14, pp. 161-179, ISSN:2076-3921 DOI

Borgonetti, Vittoria; Governa, Paolo; Morozzi, Martina; Sasia, Chiara; Videtta, Giacomina; Biagi, Marco; Galeotti, Nicoletta (2025). A Standardized Extract of Zingiber officinale Roscoe Regulates Clinical and Biological Outcomes in Two Different EAE Mouse Models. BIOMEDICINES, vol. 13, pp. 278-294, ISSN:2227-9059 DOI

Sasia, Chiara; Borgonetti, Vittoria; Mancini, Caterina; Lori, Giulia; Arbiser, Jack L.; Taddei, Maria Letizia; Galeotti, Nicoletta (2024). The Neolignan Honokiol and Its Synthetic Derivative Honokiol Hexafluoro Reduce Neuroinflammation and Cellular Senescence in Microglia Cells. CELLS, vol. 13, pp. 1652-1666, ISSN:2073-4409 DOI

Borgonetti, Vittoria; Morozzi, Martina; Galeotti, Nicoletta (2024). Neuroinflammation evoked mechanisms for neuropathic itch in the spared nerve injury mouse model of neuropathic pain. NEUROPHARMACOLOGY, vol. 259, pp. 110120-110130, ISSN:0028-3908 DOI

Mugnaini, Claudia; Brizzi, Antonella; Paolino, Marco; Scarselli, Enrico; Castelli, Riccardo; de Candia, Modesto; Gambacorta, Nicola; Nicolotti, Orazio; Kostrzewa, Magdalena; Kumar, Poulami; Mahmoud, Ali Mokhtar; Borgonetti, Vittoria; Iannotta, Monica; Morace, Andrea; Galeotti, Nicoletta; Maione, Sabatino; Altomare, Cosimo D.; Ligresti, Alessia; Corelli, Federico (2024). Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo. ACS CHEMICAL NEUROSCIENCE, vol. 15, pp. 955-971, ISSN:1948-7193 DOI

Campagnoli, Lucrezia Irene Maria; Marchesi, Nicoletta; Varesi, Angelica; Morozzi, Martina; Mascione, Linda; Ricevuti, Giovanni; Esposito, Ciro; Galeotti, Nicoletta; Pascale, Alessia (2024). New therapeutic avenues in multiple sclerosis: is there a place for gut microbiota-based treatments?. PHARMACOLOGICAL RESEARCH, vol. 209, pp. 107456-107478, ISSN:1043-6618 DOI

Borgonetti, Vittoria; Vozella, Valentina; Ware, Tim; Cruz, Bryan; Bullard, Ryan; Cravatt, Benjamin F.; Galeotti, Nicoletta; Roberto, Marisa (2024). Excessive alcohol intake produces persistent mechanical allodynia and dysregulates the endocannabinoid system in the lumbar dorsal root ganglia of genetically-selected Marchigian Sardinian alcohol-preferring rats. PHARMACOLOGICAL RESEARCH, vol. 209, pp. 107462-107474, ISSN:1043-6618 DOI

Borgonetti, Vittoria; Galeotti, Nicoletta (2023). Novel Combination of Choline with Withania somnifera (L.) Dunal, and Bacopa monnieri (L.) Wetts Reduced Oxidative Stress in Microglia Cells, Promoting Neuroprotection. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24, pp. 14038-14051, ISSN:1422-0067 DOI Accesso ONLINE all'editore

Borgonetti, Vittoria; Galeotti, Nicoletta (2023). Honokiol-Rich Magnolia officinalis Bark Extract Attenuates Trauma-Induced Neuropathic Pain. ANTIOXIDANTS, vol. 12, pp. 1518-1534, ISSN:2076-3921 DOI

Borgonetti, Vittoria; Caroli, Clarissa; Governa, Paolo; Virginia, Brighenti; Pollastro, Federica; Franchini, Silvia; Manetti, Fabrizio; Les, Francisco; López, Victor; Pellati, Federica; Galeotti, Nicoletta (2023). Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol. PHYTOTHERAPY RESEARCH, pp. 1-17, ISSN:0951-418X DOI

Borgonetti, Vittoria; Sasia, Chiara; Morozzi, Martina; Cenci, Lorenzo; Galeotti, Nicoletta (2023). Protection against Microglia Senescence by the Dietary Supplement Dekosilhue® in BV2 Cells: A New Perspective for Obesity and Related Complications. NUTRACEUTICALS, vol. 3, pp. 250-261, ISSN:1661-3821 DOI

Borgonetti, Vittoria; Mugnaini, Claudia; Corelli, Federico; Galeotti, Nicoletta (2023). The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition. BIOMEDICINES, vol. 11, pp. 1546-1560, ISSN:2227-9059 DOI

Borgonetti, Vittoria; Galeotti, Nicoletta (2023). Posttranscriptional Regulation of Gene Expression Participates in the Myelin Restoration in Mouse Models of Multiple Sclerosis: Antisense Modulation of HuR and HuD ELAV RNA Binding Protein. MOLECULAR NEUROBIOLOGY, pp. 1-17, ISSN:0893-7648 DOI

Borgonetti, Vittoria; Galeotti, Nicoletta (2023). Microglia senescence is related to neuropathic pain-associated comorbidities in the spared nerve injury model. PAIN, vol. 164, pp. 1106-1117, ISSN:0304-3959 DOI

Borgonetti, Vittoria; Anceschi, Lisa; Brighenti, Virginia; Corsi, Lorenzo; Governa, Paolo; Manetti, Fabrizio; Pellati, Federica; Galeotti, Nicoletta (2023). Cannabidiol-rich non-psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms by regulation of CB2-mediated microglial neuroinflammation. PHYTOTHERAPY RESEARCH, vol. 37, pp. 1924-1937, ISSN:1099-1573 DOI

Matacchione, Giulia; Borgonetti, Vittoria; Ramini, Deborah; Silvestrini, Andrea; Ojetti, Marta; Galeotti, Nicoletta; Olivieri, Fabiola (2023). Zingiber officinale Roscoe Rhizome Extract Exerts Senomorphic and Anti-Inflammatory Activities on Human Endothelial Cells. BIOLOGY, vol. 12, pp. 438-450, ISSN:2079-7737 DOI

Borgonetti, Vittoria; Governa, Paolo; Manetti, Fabrizio; Galeotti, Nicoletta (2023). Zingiberene, a non-zinc-binding class I HDAC inhibitor: a novel strategy for the management of neuropathic pain. PHYTOMEDICINE, pp. 154670-154680, ISSN:0944-7113 DOI

Borgonetti, Vittoria; Roberts, Amanda J.; Bajo, Michal; Galeotti, Nicoletta; Roberto, Marisa (2023). Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: a mouse model of alcohol‐evoked neuropathic pain. BRITISH JOURNAL OF PHARMACOLOGY, pp. 1-16, ISSN:0007-1188 DOI

Borgonetti, Vittoria; López, Víctor; Galeotti, Nicoletta (2022). Ylang-ylang (Cananga odorata (Lam.) Hook. f. & Thomson) essential oil reduced neuropathic-pain and associated anxiety symptoms in mice. JOURNAL OF ETHNOPHARMACOLOGY, pp. 115362-115385, ISSN:0378-8741 DOI

Borgonetti V.; Meacci E.; Pierucci F.; Romanelli M.N.; Galeotti N. (2022). Dual HDAC/BRD4 Inhibitors Relieves Neuropathic Pain by Attenuating Inflammatory Response in Microglia After Spared Nerve Injury. NEUROTHERAPEUTICS, pp. 1-15, ISSN:1933-7213 DOI

Maach S.; Chiaramonte N.; Borgonetti V.; Sarno F.; Pierucci F.; Dei S.; Teodori E.; Altucci L.; Meacci E.; Galeotti N.; Romanelli M.N. (2022). Dual HDAC–BRD4 inhibitors endowed with antitumor and antihyperalgesic activity. MEDICINAL CHEMISTRY RESEARCH, pp. 1-15, ISSN:1054-2523 DOI

Borgonetti, Vittoria; Pressi, Giovanna; Bertaiola, Oriana; Guarnerio, Chiara; Mandrone, Manuela; Chiocchio, Ilaria; Galeotti, Nicoletta (2022). Attenuation of neuroinflammation in microglia cells by extracts with high content of rosmarinic acid from in vitro cultured Melissa officinalis L. cells. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, pp. 114969-114998, ISSN:0731-7085 DOI

Borgonetti, Vittoria; Biagi, Marco; Galeotti, Nicoletta; Manetti, Fabrizio; Governa, Paolo (2022). Investigation on the neuroprotective effect of a cannabidiol-enriched non-psychotropic Cannabis sativa L. extract in an in vitro model of excitotoxicity. FITOTERAPIA, pp. 105315-105345, ISSN:1873-6971 DOI

Vittoria Borgonetti, Mirco Giusti, Francesca Gamuzza, Martina Morozzi, Chiara Sasia, Maddalena Giomi, Livia Comparini, Nicoletta Galeotti (2022). ESTRATTO STANDARDIZZATO DI ZINGIBER OFFICINALE ROSCOE COME INTERVENTO NUTRACEUTICO NEUROPROTETTIVO PER IL CONTROLLO DEGLI ESITI CLINICI E BIOLOGICI DELLA SCLEROSI MULTIPLA. In: XXX CONGRESSO NAZIONALE DI FITOTERAPIA, Tipografia Senese, pp. 47-48.

Vittoria Borgonetti, Cristina Benatti, Paolo Governa, Giovanni Isoldi, Federica Pellati, Silvia Alboni, Fabio Tascedda, Monica Montopoli, Nicoletta Galeotti, Fabrizio Manetti, Elisabetta Miraldi, Marco Biagi, Giovanna Rigillo (2022). Non-psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors-, endocannabinoids- and NF-κB-mediated signaling. PHYTOTHERAPY RESEARCH, pp. 1-15, ISSN:1099-1573 DOI Accesso ONLINE all'editore

Borgonetti, Vittoria; Cenci, Lorenzo; Galeotti, Nicoletta (2022). Anti-Inflammatory and Neuroprotective Effect of the Anti-Obesity Dietary Supplement Dekosilhue® in an In Vitro Model of Neuroinflammation. NUTRACEUTICALS, vol. 2, pp. 22-31, ISSN:1661-3821 DOI

Borgonetti, Vittoria; Galeotti, Nicoletta (2022). The Histamine H4 Receptor Participates in the Neuropathic Pain-Relieving Activity of the Histamine H3 Receptor Antagonist GSK189254. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 14314-14327, ISSN:1422-0067 DOI Accesso ONLINE all'editore

Borgonetti, Vittoria; Galeotti, Nicoletta (2022). Rosmarinic Acid Reduces Microglia Senescence: A Novel Therapeutic Approach for the Management of Neuropathic Pain Symptoms. BIOMEDICINES, vol. 10, pp. 1468-1482, ISSN:2227-9059 DOI

Borgonetti V.; Galeotti N. (2021). Quantitative analysis of mor-1 internalization in spinal cord of morphine-tolerant mice. In: Borgonetti, V; Galeotti, N. Methods in Molecular Biology, pp. 99-108, New York: Humana Press Inc., ISBN:978-1-0716-0883-8. DOI

Borgonetti V.; Galeotti N. (2021). Fluorescence colocalization analysis of cellular distribution of mor-1. In: Borgonetti, V; Galeotti, N. Methods in Molecular Biology, pp. 27-34, New York: Humana Press Inc., ISBN:978-1-0716-0883-8. DOI

Vittoria Borgonetti, Paolo Governa, Marco Biagi, Federica Pellati, Nicoletta Galeotti (2021). ZINGIBER OFFICINALE ROSCOE RHIZOME EXTRACT ALLEVIATES NEUROPATHIC PAIN IN MICE BY REDUCING NEUROINFLAMMATION THROUGH THE INHIBITION OF CLASS I HDAC ISOFORMS. In: The 40th Congress of the Italian Pharmacological Society (SIF)-THE SCIENTIFIC VALUE AND APPROPRIATE USE OF DRUGS, Edra, pp. 49-50.

Vittoria Borgonetti, Amanda Roberts, Nicoletta Galeotti, Marisa Roberto (2021). CHRONIC ETHANOL EXPOSURE INDUCES NEUROPATHIC PAIN IN MICE BY PROMOTING NEUROINFLAMMATION. In: The 40th Congress of the Italian Pharmacological Society (SIF)-THE SCIENTIFIC VALUE AND APPROPRIATE USE OF DRUGS, Edra, pp. 50-51.

Galeotti, N (2021). A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract alleviates neuropathic pain by inhibiting neuroinflammation. PLANTA MEDICA, vol. 87, pp. 1280-1280, ISSN:1439-0221 DOI

Borgonetti, Vittoria; Galeotti, Nicoletta (2021). Combined inhibition of histone deacetylases and BET family proteins as epigenetic therapy for nerve injury-induced neuropathic pain. PHARMACOLOGICAL RESEARCH, vol. 165, pp. 105431-105441, ISSN:1043-6618 DOI

Borgonetti V.; Sanna M.D.; Lucarini L.; Galeotti N. (2021). Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis. NEUROTHERAPEUTICS, vol. 18, pp. 412-419, ISSN:1933-7213 DOI

Borgonetti, Vittoria; Galeotti, Nicoletta (2021). Intranasal delivery of an antisense oligonucleotide to the RNA-binding protein HuR relieves nerve injury-induced neuropathic pain. PAIN, vol. 162, pp. 1500-1510, ISSN:0304-3959 DOI

Borgonetti V.; Coppi E.; Galeotti N. (2021). Targeting the rna-binding protein hur as potential thera-peutic approach for neurological disorders: Focus on amyo-trophic lateral sclerosis (als), spinal muscle atrophy (sma) and multiple sclerosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 10394-10406, ISSN:1422-0067 DOI

Romanelli, Maria Novella; Borgonetti, Vittoria; Galeotti, Nicoletta (2021). Dual BET/HDAC inhibition to relieve neuropathic pain: recent advances, perspectives, and future opportunities. PHARMACOLOGICAL RESEARCH, pp. 105901-105916, ISSN:1043-6618 DOI

Borgonetti V.; Governa P.; Manetti F.; Miraldi E.; Biagi M.; Galeotti N. (2021). A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor. JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 73, pp. 1161-1168, ISSN:0022-3573 DOI

Sanna M.D.; Borgonetti V.; Masini E.; Galeotti N. (2020). Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 868, pp. 1-10, ISSN:0014-2999 DOI Accesso ONLINE all'editore

Sanna, Maria Domenica; Borgonetti, Vittoria; Galeotti, Nicoletta (2020). μ Opioid Receptor-Triggered Notch-1 Activation Contributes to Morphine Tolerance: Role of Neuron–Glia Communication. MOLECULAR NEUROBIOLOGY, vol. 57, pp. 331-345, ISSN:0893-7648 DOI

Borgonetti, Vittoria; Governa, Paolo; Biagi, Marco; Galeotti, Nicoletta (2020). Novel Therapeutic Approach for the Management of Mood Disorders: In Vivo and In Vitro Effect of a Combination of L-Theanine, Melissa officinalis L. and Magnolia officinalis Rehder & E.H. Wilson. NUTRIENTS, vol. 12, pp. 1803-1813, ISSN:2072-6643 DOI

Borgonetti, Vittoria; Les, Francisco; López, Víctor; Galeotti, Nicoletta (2020). Attenuation of Anxiety-Like Behavior by Helichrysum stoechas (L.) Moench Methanolic Extract through Up-Regulation of ERK Signaling Pathways in Noradrenergic Neurons. PHARMACEUTICALS, vol. 13, pp. 472-486, ISSN:1424-8247 DOI

Borgonetti, Vittoria; Governa, Paolo; Biagi, Marco; Pellati, Federica; Galeotti, Nicoletta (2020). Zingiber officinale Roscoe rhizome extract alleviates neuropathic pain by inhibiting neuroinflammation in mice. PHYTOMEDICINE, vol. --, pp. 153307-153317, ISSN:0944-7113 DOI

Sanna, Maria Domenica; Manassero, Giusi; Vercelli, Alessandro; Herdegen, Thomas; Galeotti, Nicoletta (2020). The isoform-specific functions of the c-Jun N-terminal kinase (JNK) in a mouse model of antiretroviral-induced painful peripheral neuropathy. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 868, pp. 1-6, ISSN:0014-2999 DOI

Murineddu, Gabriele; Asproni, Battistina; Corona, Paola; Gessi, Stefania; Merighi, Stefania; Battistello, Enrica; Sturaro, Chiara; Calò, Girolamo; Galeotti, Nicoletta; Temml, Veronika; Herdlinger, Sonja; Schuster, Daniela; Pinna, Gerard A. (2020). Synthesis, biological evaluation and docking studies of a novel class of sulfur-bridged diazabicyclo[3.3.1]nonanes. BIOORGANIC CHEMISTRY, pp. 104072-104082, ISSN:0045-2068 DOI

Sanna, Maria Domenica; Les, Francisco; Lopez, Victor; Galeotti, Nicoletta (2019). Lavender (Lavandula angustifolia Mill.) Essential Oil Alleviates Neuropathic Pain in Mice With Spared Nerve Injury. FRONTIERS IN PHARMACOLOGY, vol. 10, pp. 472-485, ISSN:1663-9812 DOI

Sanna, Maria Domenica*; Galeotti, Nicoletta (2018). The HDAC1/c-JUN complex is essential in the promotion of nerve injury-induced neuropathic pain through JNK signaling. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 825, pp. 99-106, ISSN:0014-2999 DOI Accesso ONLINE all'editore

Sanna, MARIA DOMENICA; Mello, Tommaso; Masini, Emanuela; Galeotti, Nicoletta (2018). Activation of ERK/CREB pathway in noradrenergic neurons contributes to hypernociceptive phenotype in H4 receptor knockout mice after nerve injury. NEUROPHARMACOLOGY, vol. 128, pp. 340-350, ISSN:0028-3908 DOI Accesso ONLINE all'editore

Vittoria Borgonetti, Paolo Governa, Marco Biagi, Nicoletta Galeotti (2018). ANTI-NOCICEPTIVE EFFECTS OF A STANDARDIZED EXTRACT OF ZINGIBER OF- FICINALE ROSCOE IN A MICE MODEL OF NEUROPATHIC PAIN. In: XXVII CONGRESSO NAZIONALE DI FITOTERAPIA, Tipografia Senese, pp. 9-10.

Sanna, Maria Domenica; Quattrone, Alessandro; Galeotti, Nicoletta (2018). Antidepressant-like actions by silencing of neuronal ELAV-like RNA-binding proteins HuB and HuC in a model of depression in male mice. NEUROPHARMACOLOGY, vol. 135, pp. 444-454, ISSN:0028-3908 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2017). St. John's Wort Potentiates anti-Nociceptive Effects of Morphine in Mice Models of Neuropathic Pain. PAIN MEDICINE, vol. 18, pp. 1334-1343, ISSN:1526-2375 DOI

Sanna, Maria Domenica; Lucarini, Laura; Durante, Mariaconcetta; Ghelardini, Carla; Masini, Emanuela; Galeotti, Nicoletta (2017). Histamine H4 receptor agonist-induced relief from painful peripheral neuropathy is mediated by inhibition of spinal neuroinflammation and oxidative stress. BRITISH JOURNAL OF PHARMACOLOGY, vol. 174, pp. 28-40, ISSN:0007-1188 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2017). Effect of amitriptyline treatment on neurofilament-H protein in an experimental model of depression. BRAIN RESEARCH BULLETIN, vol. 128, pp. 1-6, ISSN:0361-9230 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Thurmond, Robin L.; Masini, Emanuela; Galeotti, Nicoletta (2017). Behavioural phenotype of histamine H4 receptor knockout mice: Focus on central neuronal functions. NEUROPHARMACOLOGY, vol. 114, pp. 48-57, ISSN:0028-3908 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2017). Spinal astrocytic c-Jun N-terminal kinase (JNK) activation as counteracting mechanism to the amitriptyline analgesic efficacy in painful peripheral neuropathies. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 798, pp. 85-93, ISSN:0014-2999 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2017). HuD-mediated distinct BDNF regulatory pathways promote regeneration after nerve injury. BRAIN RESEARCH, vol. 1659, pp. 55-63, ISSN:1872-6240 DOI

Sanna, Maria Domenica; Quattrone, Alessandro; Galeotti, Nicoletta (2017). Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis. NEUROPHARMACOLOGY, vol. 123, pp. 116-125, ISSN:0028-3908 DOI

Sanna, Maria Domenica; Guandalini, Luca; Romanelli, Maria Novella; Galeotti, Nicoletta (2017). The new HDAC1 inhibitor LG325 ameliorates neuropathic pain in a mouse model. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, vol. 160, pp. 70-75, ISSN:0091-3057 DOI Accesso ONLINE all'editore

Galeotti, Nicoletta (2017). Hypericum perforatum (St John's wort) beyond depression: a therapeutic perspective for pain conditions. JOURNAL OF ETHNOPHARMACOLOGY, vol. 200, pp. 136-146, ISSN:0378-8741 DOI

Sanna, Maria Domenica; Galeotti, Nicoletta (2017). Central neuronal functions of histamine H4 receptors. ONCOTARGET, vol. 8, pp. 12556-12557, ISSN:1949-2553 DOI

Galeotti, Nicoletta (2017). Targeting JNK to prevent antiretroviral neuropathy. ONCOTARGET, vol. 8, pp. 12546-12547, ISSN:1949-2553 DOI

Isacchi, Benedetta; Bergonzi, Maria Camilla; Iacopi, Romina; Ghelardini, Carla; Galeotti, Nicoletta; Bilia, Anna Rita (2017). Liposomal Formulation to Increase Stability and Prolong Antineuropathic Activity of Verbascoside. PLANTA MEDICA, vol. 83, pp. 412-419, ISSN:0032-0943 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2016). Blockade of the spinal BDNF-activated JNK pathway prevents the development of antiretroviral-induced neuropathic pain. NEUROPHARMACOLOGY, vol. 105, pp. 543-552, ISSN:0028-3908 DOI

Sanna, M.D.; Galeotti, N.; Lucarini, L.; Lanzi, C.; Ghelardini, C.; Masini, E. (2016). Characterization of behavioral phenotypes in histamine H4-receptor knockout mice. INFLAMMATION RESEARCH, vol. 65, pp. 1-53, ISSN:1023-3830 DOI

Sanna, M.D.; Peroni, D.; Mello, T.; Ghelardini, C.; Quattrone, A.; Galeotti, N (2016). Increase of neurofilament-H protein in sensory neurons in antiretroviral neuropathy: Evidence for a neuroprotective response mediated by the RNA-binding protein HuD. PHARMACOLOGICAL RESEARCH, vol. 111, pp. 23-33, ISSN:1043-6618 DOI Accesso ONLINE all'editore

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2016). Altered Expression of Cytoskeletal and Axonal Proteins in Oxaliplatin-Induced Neuropathy. PHARMACOLOGY, vol. 97, pp. 146-150, ISSN:0031-7012 DOI Accesso ONLINE all'editore

Sanna, Maria Domenica; Stark, Holger; Lucarini, Laura; Ghelardini, Carla; Masini, Emanuela; Galeotti, Nicoletta (2015). Histamine H4 receptor activation alleviates neuropathic pain through differential regulation of ERK, JNK and P38 MAPK phosphorylation. PAIN, vol. 156, pp. 2492-2504, ISSN:0304-3959 DOI

Sanna MD; Peroni D; Quattrone A; Ghelardini C; Galeotti N (2015). Spinal RyR2 pathway regulated by the RNA-binding protein HuD induces pain hypersensitivity in antiretroviral neuropathy.. EXPERIMENTAL NEUROLOGY, vol. 267, pp. 53-63, ISSN:0014-4886 DOI

Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Nicoletta Galeotti, Tommaso Cassano, Fernando Benetti, Renato Corradetti, Patrizio Blandina (2015). Brain histamine is crucial for selective serotonin reuptake inhibitors behavioral and neurochemical effects. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, vol. 18, pp. 1-10, ISSN:1461-1457 DOI

Sanna, Maria Domenica; Mello, Tommaso; Ghelardini, Carla; Galeotti, Nicoletta (2015). Inhibition of spinal ERK1/2-c-JUN signaling pathway counteracts the development of low doses morphine-induced hyperalgesia. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 764, pp. 271-277-277, ISSN:0014-2999 DOI

Sanna, Maria Domenica; Monti, Martina; Casella, Luigi; Roggeri, Riccardo; Galeotti, Nicoletta; Morbidelli, Lucia (2015). Neuronal effects of a nickel-piperazine/NO donor complex in rodents. PHARMACOLOGICAL RESEARCH, vol. 99, pp. 162-173, ISSN:1043-6618 DOI

Sanna, Maria Domenica; Ghelardini, Carla; Galeotti, Nicoletta (2015). Activation of JNK pathway in spinal astrocytes contributes to acute ultra-low-dose morphine thermal hyperalgesia. PAIN, vol. 156, pp. 1265-75-1275, ISSN:0304-3959 DOI

M. D. Sanna;C. Ghelardini;N. Galeotti (2015). Differential contribution of Gαi/o subunits in the response to food deprivation.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 750, pp. 27-31, ISSN:0014-2999 DOI Accesso ONLINE all'editore

M.D. Sanna;A. Quattrone;T. Mello;C. Ghelardini;N. Galeotti (2014). The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy. EXPERIMENTAL NEUROLOGY, vol. 261, pp. 343-353, ISSN:0014-4886 DOI

Nicoletta Galeotti;Anna Maidecchi;Luisa Mattoli;Michela Burico;Carla Ghelardini (2014). St. John's Wort seed and feverfew flower extracts relieve painful diabetic neuropathy in a rat model of diabetes. FITOTERAPIA, vol. 92, pp. 23-33, ISSN:1971-551X DOI

Gustavo Provensi, Roberto Coccurello, Hayato Umehara, Leonardo Munari, Giacomo Giacovazzo, Nicoletta Galeotti, Daniele Nosi, Silvana Gaetani, Adele Romano, Anna Moles, Patrizio Blandina, Maria Beatrice Passani (2014). Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 111, pp. 11527-11532, ISSN:0027-8424 DOI

GALEOTTI N; GHELARDINI C (2014). Hypericum perforatum L. as adjuvant of opioid analgesia in an animal model of migraine. BRITISH JOURNAL OF MEDICINE AND MEDICAL RESEARCH, vol. 4, pp. 1591-1603, ISSN:2231-0614

Bibiana Mozzaquatro Gai;Maria Domenica Sanna;Andr? Luiz Stein;Gilson Zeni;Nicoletta Galeotti;Cristina Wayne Nogueira (2014). ERK1/2 phosphorylation is involved in the antidepressant-like action of 2,5-diphenyl-3-(4-fluorophenylseleno)-selenophene in mice. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 736, pp. 44-54, ISSN:0014-2999 DOI

M.D. Sanna;A. Quattrone;C. Ghelardini;N. Galeotti (2014). PKC-mediated HuD–GAP43 pathway activation in a mouse model of antiretroviral painful neuropathy. PHARMACOLOGICAL RESEARCH, vol. 81, pp. 44-53, ISSN:1043-6618 DOI

Maria Domenica Sanna;Carla Ghelardini;Nicoletta Galeotti (2014). Regionally selective activation of ERK and JNK in morphine paradoxical hyperalgesia: A step toward improving opioid pain therapy. NEUROPHARMACOLOGY, vol. 86, pp. 67-77, ISSN:0028-3908 DOI

Nicoletta Galeotti;Mersedeh Farzad;Enrica Bianchi;Carla Ghelardini (2014). PKC-Mediated Potentiation of Morphine Analgesia by St. John’s Wort in Rodents and Humans. JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 124, pp. 409-417, ISSN:1347-8613 DOI

M.D. Sanna; N. Galeotti; L. Lucarini; C. Lanzi; H. Stark; C. Ghelardini; E. Masini (2014). HISTAMINE H4 RECEPTOR ACTIVATION INDUCES ANTINOCICEPTION IN A NEUROPATHIC PAIN MODEL. INFLAMMATION RESEARCH, vol. 63 (Suppl 1), pp. S16-S17, ISSN:1023-3830 DOI

Galeotti N;Ghelardini C (2013). Inhibition of the PKCγ-ε Pathway Relieves from Meningeal Nociception in an Animal Model: An Innovative Perspective for Migraine Therapy?. NEUROTHERAPEUTICS, vol. 10, pp. 329-339, ISSN:1933-7213 DOI

Nicoletta Galeotti;Carla Ghelardini (2013). Reversal of NO-induced nociceptive hypersensitivity by St. John’s wort and hypericin: NF-κB, CREB and STAT1 as molecular targets. PSYCHOPHARMACOLOGY, vol. 227, pp. 149-163, ISSN:0033-3158 DOI

Nicoletta Galeotti;Carla Ghelardini (2013). PKC-Dependent Signaling Pathways within PAG and Thalamus Contribute to the Nitric Oxide-Induced Nociceptive Behavior. ISRN PAIN, vol. 2013, pp. 1-10, ISSN:2314-4718 DOI

N. Galeotti;C. Ghelardini (2013). St. John's wort reversal of meningeal nociception: A natural therapeutic perspective for migraine pain. PHYTOMEDICINE, vol. 20, pp. 930-938, ISSN:0944-7113 DOI

Nicoletta Galeotti;Maria Domenica Sanna;Carla Ghelardini (2013). Pleiotropic effect of histamine H4 receptor modulation in the central nervous system. NEUROPHARMACOLOGY, vol. 71, pp. 141-147, ISSN:0028-3908 DOI

N Galeotti; C Ghelardini (2013). St. John's wort relieves pain in an animal model of migraine.. EUROPEAN JOURNAL OF PAIN, vol. 17, pp. 369-381, ISSN:1090-3801 DOI

Provensi G.; Munari L.; Blandina P.; Galeotti N.; Passani M. B. (2012). INTERACTIONS BETWEEN NEURONAL HISTAMINE AND OLEOYLETHANOLAMIDE IN THE CONTROL OF FOOD INTAKE: A BEHAVIORAL AND IMMUNOHISTOCHEMICAL STUDY. BEHAVIOURAL PHARMACOLOGY, vol. 23, pp. 626-635, ISSN:0955-8810 DOI

G. Provensi; L. Munari; P. Blandina; N. Galeotti; M. B. Passani (2012). THE ANOREXIANT EFFECT OF OLEOYLETHANOLAMIDE IS MODULATED BY NEURONAL HISTAMINE. INFLAMMATION RESEARCH, vol. 61, pp. 62-62, ISSN:1023-3830

N. Galeotti;C. Ghelardini (2012). Regionally selective activation and differential regulation of ERK, JNK and p38 MAP kinase signalling pathway by protein kinase C in mood modulation.. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, vol. 15, pp. 781-793, ISSN:1461-1457 DOI Accesso ONLINE all'editore

N. Galeotti;C. Ghelardini (2012). Selective modulation of the PKCɛ/p38MAP kinase signalling pathway for the antidepressant-like activity of amitriptyline.. NEUROPHARMACOLOGY, vol. 62, pp. 289-296, ISSN:0028-3908 DOI Accesso ONLINE all'editore

M. Biava;G. C. Porretta;G. Poce;C. Battilocchio;M. Botta;F. Manetti;M. Rovini;A. Cappelli;L. Sautebin;A. Rossi;C. Pergola;C. Ghelardini;N. Galeotti;F. Makovec;A. Giordani;P. Anzellotti;S. Tacconelli;P. Patrignani;M. Anzini (2011). Enlarging the NSAIDs family: ether, ester and acid derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.. CURRENT MEDICINAL CHEMISTRY, vol. 18, pp. 1540-1554, ISSN:0929-8673 DOI

Isacchi B; Iacopi R; Bergonzi MC; Ghelardini C; Galeotti N; Norcini M; Vivoli E; Vincieri FF; Bilia AR (2011). Antihyperalgesic activity of verbascoside in two models of neuropathic pain.. JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 63, pp. 594-601, ISSN:0022-3573 DOI

E. Bianchi;N. Galeotti;C. Menicacci;C. Ghelardini (2011). Contribution of G inhibitory protein alpha subunits in paradoxical hyperalgesia elicited by exceedingly low doses of morphine in mice.. LIFE SCIENCES, vol. 89, pp. 918-925, ISSN:0024-3205 DOI Accesso ONLINE all'editore

B Isacchi; V. Fabbri; N Galeotti; MC Bergonzi; A Karioti; C Ghelardini; MG Vannucchi; AR Bilia (2011). Salvianolic acid B and its liposomal formulations: anti-hyperalgesic activity in the treatment of neuropathic pain.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 44, pp. 552-558, ISSN:0928-0987 DOI

L. Munari; G. Provensi; M.B. Passani; N. Galeotti; T. Cassano; P. Blandina (2011). IS BRAIN HISTAMINE INVOLVED IN DEPRESSION?. INFLAMMATION RESEARCH, vol. 60, pp. 339-339, ISSN:1023-3830

N. Galeotti;C. Ghelardini (2011). Antidepressant phenotype by inhibiting the phospholipase Cβ(1)--protein kinase Cγ pathway in the forced swim test.. NEUROPHARMACOLOGY, vol. 60, pp. 937-943, ISSN:0028-3908 DOI Accesso ONLINE all'editore

V Mercati; F F Vincieri; A R Bilia; C Ghelardini; N Galeotti (2011). Use of hypericum perforatum extracts in the treatment of neuropathic pain. Numero: EP Patent 2,247,296, 2010; US8906430 US Patent Number, December 9, 2014 Aboca SpA Società Agricola

L. Munari; N. Galeotti; H. Ohtsu; P. Blandina; M.B. Passani (2010). OLEOYLETHANOLAMIDE AND BRAIN HISTAMINE INTERACT TO REGULATE FEEDING BEHAVIOUR. INFLAMMATION RESEARCH, vol. 59, pp. S318-S318, ISSN:1023-3830

L. Munari; M.B. Passani; N. Galeotti; P. Giannoni; H. Ohtsu; P. Blandina (2010). EFFECTS OF CITALOPRAM ON TAIL SUSPENSION TEST REQUIRE THE PRESENCE OF NEURONAL HISTAMINE. INFLAMMATION RESEARCH, vol. 59, pp. S318-S318, ISSN:1023-3830

Nicoletta Galeotti;Elisa Vivoli;Anna Rita Bilia;Franco Francesco Vincieri;Carla Ghelardini (2010). St. John's Wort reduces neuropathic pain through a hypericin-mediated inhibition of the protein kinase C γ and ɛ activity. BIOCHEMICAL PHARMACOLOGY, vol. 79, pp. 1327-1336, ISSN:0006-2952 DOI

N.Galeotti; E. Vivoli; A.R. Bilia; M.C. Bergonzi; A. Bartolini; C. Ghelardini (2010). A Prolonged Protein Kinase C-Mediated, Opioid-Related Antinociceptive Effect of St John's Wort in Mice. THE JOURNAL OF PAIN, vol. 11, pp. 149-159, ISSN:1526-5900 DOI

M. Biava;G. C. Porretta;G. Poce;C. Battilocchio;F. Manetti;M. Botta;S. Forli;L. Sautebin;A. Rossi;C. Pergola;C. Ghelardini;N. Galeotti;F. Makovec;A. Giordani;P. Anzellotti;P. Patrignani;M. Anzini (2010). Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, pp. 723-733, ISSN:1520-4804 DOI Accesso ONLINE all'editore

Carocci A; Lentini G; Catalano A; Cavalluzzi MM; Bruno C; Muraglia M; Colabufo NA; Galeotti N; Corbo F; Matucci R; Ghelardini C; Franchini C. (2010). Chiral aryloxyalkylamines: Selective 5-HT(1B/1D) activation and analgesic activity. CHEMMEDCHEM, vol. 5, pp. 696-704, ISSN:1860-7179 DOI

M. Norcini;E. Vivoli;N. Galeotti;E. Bianchi;A. Bartolini;C. Ghelardini (2009). Supraspinal role of protein kinase C in oxaliplatin-induced neuropathy in rat.. PAIN, vol. 146, pp. 141-147, ISSN:0304-3959 DOI Accesso ONLINE all'editore

M C Bergonzi;B Isacchi;R Iacopi;C Ghelardini;N Galeotti;M Norcini;E Vivoli;F F Vincieri;A R Bilia (2009). Antihyperalgesic activity of verbascoside in the chronic constriction injury of the sciatic nerve (CCI) and intra-articular injection of sodium monoiodoacetate (MIA) models of neuropatic pain. PLANTA MEDICA, vol. 75, pp. 45-45, ISSN:0032-0943 DOI

C. Ghelardini; N. Galeotti; E. Vivoli; I. Grazioli; C. Uslenghi (2009). The central analgesia induced by antimigraine drugs is independent from Gi proteins: superiority of a fixed combination of indomethacin, prochlorperazine and caffeine, compared to sumatriptan, in an in vivo model.. THE JOURNAL OF HEADACHE AND PAIN, vol. 10, pp. 435-440, ISSN:1129-2377 DOI Accesso ONLINE all'editore

B. Isacchi; N. Galeotti; M. C. Bergonzi; C. Ghelardini; A.R. Bilia; F.F. Vincieri (2009). Pharmacological in vivo test to evaluate the bioavailability of some St. John’s wort innovative oral preparations. PHYTOTHERAPY RESEARCH, vol. 11, pp. 197-205, ISSN:0951-418X DOI

Luigi Janiri; Giovanni Martinotti; Federico Tonioni; Carla Ghelardini; Raffaella Nicolai; Nicoletta Galeotti; Luigi Mosconi; Menotti Calvani; Alessandro Bartolini; Emerenziana Iannoni (2009). Acetyl-l-Carnitine in the Management of Pain During Methadone Withdrawal Syndrome.. CLINICAL NEUROPHARMACOLOGY, vol. 32, pp. 35-40, ISSN:0362-5664 DOI Accesso ONLINE all'editore

Nicoletta Galeotti; Alessandro Quattrone; Elisa Vivoli; Monica Norcini; Alessandro Bartolini; Carla Ghelardini (2008). Different involvement of type 1, 2, and 3 ryanodine receptors in memory processes.. LEARNING & MEMORY, vol. 15, pp. 315-323, ISSN:1072-0502 DOI Accesso ONLINE all'editore

Nicoletta Galeotti; Elisa Vivoli; Alessandro Bartolini; Carla Ghelardini (2008). A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.. JOURNAL OF NEUROCHEMISTRY, vol. 106, pp. 2385-2394, ISSN:0022-3042 DOI Accesso ONLINE all'editore

N. Galeotti; A. Quattrone; E. Vivoli; A. Bartolini; C. Ghelardini (2008). Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: An antisense study.. NEUROSCIENCE, vol. 153, pp. 814-822, ISSN:0306-4522 DOI Accesso ONLINE all'editore

Carla Ghelardini; Nicoletta Galeotti; Elisa Vivoli; Monica Norcini; Wei Zhu; George B Stefano; Massimo Guarna; Enrica Bianchi (2008). Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception.. JOURNAL OF NEUROCHEMISTRY, vol. 105, pp. 91-100, ISSN:0022-3042 DOI Accesso ONLINE all'editore

N. Galeotti; E. Vivoli; M. Norcini; A. Bartolini; C. Ghelardini (2008). An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.. NEUROPHARMACOLOGY, vol. 55, pp. 1156-1164, ISSN:0028-3908 DOI Accesso ONLINE all'editore

E Bianchi; N Galeotti; C Ghelardini; M Guarna (2008). Hypericum and derivatives thereof as analgesic potentiating agents. Numero: WO Patent 2008058938, 2008 Università degli Studi di Siena

E. Vivoli; M. Norcini; M.Bercigli; A. Maidecchi; A.R. Bilia; C. Ghelardini (2008). Antihyperalgesic Effect of Eschscholzia californica in Rat Models of Neuropatic Pain.. NATURAL PRODUCT COMMUNICATIONS, vol. 3, pp. 2099-2102, ISSN:1934-578X

G. GUERRINI; G. CICIANI; G. CAMBI; F. BRUNI; S. SELLERI; F. BESNARD; M. MONTALI; C. MARTINI; C. GHELARDINI; N. GALEOTTI; A. COSTANZO (2007). Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist, useful tools for therapy of mnemonic damage.. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15, pp. 2573-2586, ISSN:0968-0896 DOI Accesso ONLINE all'editore

Filomena Corbo; Carlo Franchini; Giovanni Lentini; Marilena Muraglia; Carla Ghelardini; Rosanna Matucci; Nicoletta Galeotti; Elisa Vivoli; Vincenzo Tortorella (2007). Synthesis and biological evaluation of chiral α-aminoanilides with central antinociceptive activity. JOURNAL OF MEDICINAL CHEMISTRY, vol. 50, pp. 1907-1915, ISSN:0022-2623 DOI Accesso ONLINE all'editore

N. Galeotti; A. Quattrone; E. Vivoli; A. Bartolini; C. Ghelardini (2007). Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.. NEUROSCIENCE, vol. 149, pp. 409-420, ISSN:0306-4522 DOI Accesso ONLINE all'editore

Nicoletta Galeotti; George B Stefano; Massimo Guarna; Enrica Bianchi; Carla Ghelardini (2006). Signaling pathway of morphine induced acute thermal hyperalgesia in mice.. PAIN, vol. 123, pp. 294-305, ISSN:0304-3959 DOI Accesso ONLINE all'editore

Renato Pirisino; Nicoletta Galeotti; Silvia Livi; Laura Raimondi; Carla Ghelardini (2006). 4-methyl benzylamine stimulates food consumption and counteracts the hypophagic effects of amphetamine acting on brain Shaker-like Kv1.1 channels.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 147, pp. 218-224, ISSN:0007-1188 DOI Accesso ONLINE all'editore

GALEOTTI N; A. BARTOLINI; GHELARDINI C (2006). Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test.. NEUROPHARMACOLOGY, vol. 50, pp. 309-316, ISSN:0028-3908, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598: DOI Accesso ONLINE all'editore

N.CESARI; C.BIANCALANI; C.VERGELLI; V. DAL PIAZ; A.GRAZIANO; P.BIAGINI; C.GHELARDINI; N.GALEOTTI; M.GIOVANNONI (2006). Arylpiperazinylalkylpyridazinones and analogues as potent and orally active antinociceptive agents: synthesis and studies on mechanism of action. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 7826-7835, ISSN:0022-2623 DOI

Di Cesare Mannelli, L.; Pacini, A.; Toscano, A.; Fortini, M.; Berti, D.; Ghelardini, C.; Galeotti, N.; Baglioni, P.; Bartolini, A. (2006). Gi/o proteins: expression for direct activation enquiry. PROTEIN EXPRESSION AND PURIFICATION, vol. 47, pp. 303-310, ISSN:1046-5928, Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495: DOI

M. ROMANELLI; N. GALEOTTI; C. GHELARDINI; D. MANETTI; E. MARTINI; F. GUALTIERI (2006). Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers. CNS DRUG REVIEWS, vol. 12, pp. 39-52, ISSN:1080-563X DOI

A R Bilia; M C Bergonzi; B Isacchi; N Galeotti; C Ghelardini; F F Vincieri (2006). Pharmacological in vivo test to evaluate the bioavailability of some St. John's wort innovative oral preparations. PLANTA MEDICA, vol. 72, pp. 241-241, ISSN:0032-0943 DOI

V. COLOTTA; D. CATARZI; F. VARANO; O. LENZI; G. FILACCHIONI; C. COSTAGLI; A. GALLI; C. GHELARDINI; N. GALEOTTI; P.GRATTERI; J.SGRIGNANI; F. DEFLORIAN; S. MORO; (2006). Structural Investigation of the 7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione Scaffold to Obtain AMPA and Kainate Receptor Selective Antagonists. Synthesis, Pharmacological and Molecular Modeling Studies. JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, pp. 6015-6026, ISSN:0022-2623 DOI Accesso ONLINE all'editore

A Bartolini; C Ghelardini; N Galeotti (2005). Analgesic drugs acting through a central cholinergic mechanism. In: A Capasso. Recent Developments in Pain Research, pp. 289-312, Fisciano: A Capasso, ISBN:8130800128.

Nicoletta Galeotti; Alessandro Bartolini; Carla Ghelardini (2005). Ryanodine receptors are involved in muscarinic antinociception in mice.. BEHAVIOURAL BRAIN RESEARCH, vol. 164, pp. 165-171, ISSN:0166-4328 DOI Accesso ONLINE all'editore

A. Toscano; L. Di Cesare Mannelli; C. Ghelardini; N. galeotti; A. bartolini; A. Pacini (2005). Transductor-effector system as model for the study of Gi protein dysfunction treatment.. In: XV Convegno Nazionale del Gruppo Italiano per lo Studio della Neuromorfologia (GISN), Bologna, 24-25 Novembre, Gruppo Italiano per lo Studio della Neuromorfologia (GISN), pp. 0-0.

D. Manetti; L. Di Cesare Mannelli; S. Dei; N. Galeotti; C. Ghelardini; M. Romanelli; S. Scapecchi; E. Teodori; A. Pacini; A. Bartolini; F. Gualtieri (2005). Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, pp. 6491-6503, ISSN:0022-2623 DOI

Pirisino R;Ghelardini C;De Siena G;Malmberg P;Galeotti N;Cioni L;Banchelli G;Raimondi L (2005). Methylamine: a new endogenous modulator of neuron firing?. MEDICAL SCIENCE MONITOR, vol. 11, pp. 257-261, ISSN:1234-1010

Massimo Guarna; Carla Ghelardini; Nicoletta Galeotti; George B Stefano; Enrica Bianchi (2005). Neurotransmitter role of endogenous morphine in CNS.. MEDICAL SCIENCE MONITOR, vol. 11, pp. RA190-RA193, ISSN:1234-1010

Nicoletta Galeotti; Alessandro Bartolini; Menotti Calvani; Raffaella Nicolai; Carla Ghelardini (2004). Acetyl-L-carnitine requires phospholipase C-IP3 pathway activation to induce antinociception.. NEUROPHARMACOLOGY, vol. 47, pp. 286-294, ISSN:0028-3908 DOI Accesso ONLINE all'editore

S. SCAPECCHI; E. MARTINI; D. MANETTI; C. GHELARDINI; C. MARTELLI; S. DEI; N. GALEOTTI; L. GUANDALINI; M. ROMANELLI; E. TEODORI (2004). Structure-activity relationship studies on unifiram (DM232) and sunifiram (DM235), two novel and potent cognition enhancing drugs. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 12, pp. 71-85, ISSN:0968-0896 DOI

N. GALEOTTI; A. BARTOLINI; C. GHELARDINI (2004). Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype.. BEHAVIOURAL BRAIN RESEARCH, vol. 153, pp. 409-417, ISSN:0166-4328 DOI

Nicoletta Galeotti; Petra Malmberg-Aiello; Alessandro Bartolini; Walter Schunack; Carla Ghelardini (2004). H1-receptor stimulation induces hyperalgesia through activation of the phospholipase C-PKC pathway.. NEUROPHARMACOLOGY, vol. 47, pp. 295-303, ISSN:0028-3908 DOI Accesso ONLINE all'editore

GUARNA M; GHELARDINI C; GALEOTTI N; A. BARTOLINI; NOLI L; NERI C; STEFANO GB; BIANCHI E (2004). Effect of endogenous morphine deprivation on memory retention of passive avoidance learning in mice.. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, vol. 7, pp. 311-319, ISSN:1461-1457 DOI

Carla Ghelardini; Nicoletta Galeotti; Irene Grazioli; Carla Uslenghi (2004). Indomethacin, alone and combined with prochlorperazine and caffeine, but not sumatriptan, abolishes peripheral and central sensitization in in vivo models of migraine.. THE JOURNAL OF PAIN, vol. 5, pp. 413-419, ISSN:1526-5900 DOI Accesso ONLINE all'editore

N. GALEOTTI; A. BARTOLINI; C. GHELARDINI (2004). Alpha-2 agonits induce amnesia through activation of the Gi-protein signalling pathway.. NEUROSCIENCE, vol. 126, pp. 451-460, ISSN:0306-4522 DOI

C. GHELARDINI; N. GALEOTTI; C. USLENGHI; I. GRAZIOLI; A. BARTOLINI (2004). Prochlorperazine induces central antinociception mediated by the muscarinic system.. PHARMACOLOGICAL RESEARCH, vol. 50, pp. 351-358, ISSN:1043-6618 DOI

N. GALEOTTI; A. BARTOLINI; C. GHELARDINI (2004). Role of intracellular calcium in acute thermal pain perception. NEUROPHARMACOLOGY, vol. 47, pp. 935-944, ISSN:0028-3908 DOI Accesso ONLINE all'editore

D. Manetti; L.Di Cesare Mannelli; S. Dei; N. Galeotti; C. Ghelardini; M.N. Romanelli; S. Scapecchi; E. Teodori; A. Bartolini; F. Gualtieri (2004). Progettazione, sintesi e valutazione farmacologica preliminare di attivatori diretti delle proteine Gi. In: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana, Pisa, 6-10 Settembre 2004, Società Chimica Italiana, pp. 249-249.

R. Pirisino; C. Ghelardini; A. Pacini; N. Galeotti; L. Raimondi (2004). Methylamine, but not ammonia, is hypophagic in mouse by interaction with brain Kv1.6 channel subtype.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 142, pp. 381-389, ISSN:0007-1188 DOI

GIOVANNONI M.P.; VERGELLI C.; GHELARDINI C.; GALEOTTI N.; BARTOLINI A.; V. DAL PIAZ (2003). [(3-chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents. JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, pp. 1055-1059, ISSN:0022-2623 DOI

D. MANETTI; E. MARTINI; C. GHELARDINI; S. DEI; N. GALEOTTI; L. GUANDALINI; M. ROMANELLI; S. SCAPECCHI; E. TEODORI; A. BARTOLINI; F. GUALTIERI (2003). 4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, pp. 2303-2306, ISSN:0960-894X DOI

N. GALEOTTI; A. BARTOLINI; C. GHELARDINI (2003). Diphenhydramine-induced amnesia is mediated by Gi-protein activation.. NEUROSCIENCE, vol. 122, pp. 471-478, ISSN:0306-4522 DOI

C. GHELARDINI; A. QUATTRONE; N. GALEOTTI; S. LIVI; G. BANCHELLI; L. RAIMONDI; R. PIRISINO. (2003). Antisense knockdown of the Shaker Kv1.1 gene family abolishes the central stimulatory effect of amphetamines in mice and rats.. NEUROPSYCHOPHARMACOLOGY, vol. 28, pp. 1096-1105, ISSN:0893-133X DOI

N. GALEOTTI; A. BARTOLINI; C. GHELARDINI (2003). THE PHOSPHOLIPASE C-IP3 PATHWAY IS INVOLVED IN MUSCARINIC ANTINOCICEPTION. NEUROPSYCHOPHARMACOLOGY, vol. 28, pp. 888-897, ISSN:0893-133X DOI

M. Guarna; A. Bartolini; C. Ghelardini; N. Galeotti; L. Bracci; G. B. Stefano; E. Bianchi (2003). Anti-mu opioid antiserum against the third external loop of the cloned mu-opioid receptor acts as a mu receptor neutral antagonist.. MOLECULAR BRAIN RESEARCH, vol. 119, pp. 100-110, ISSN:0169-328X DOI Accesso ONLINE all'editore

Maurizio Anzini; Laura Canullo; Carlo Braile; Andrea Cappelli; Andrea Gallelli; Salvatore Vomero; M. Cristina Menziani; Pier G De; Milena Rizzo; Simona Collina; Ornella Azzolina; Massimo Sbacchi; Carla Ghelardini; Nicoletta Galeotti (2003). Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, pp. 3853-3864, ISSN:0022-2623 DOI Accesso ONLINE all'editore

N.GALEOTTI; C.GHELARDINI; A.PITTALUGA; A. PUGLIESE; A.BARTOLINI; D.MANETTI; M.ROMANELLI; F.GUALTIERI (2003). AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, vol. 368, pp. 538-545, ISSN:0028-1298

N. GALEOTTI; A. BARTOLINI; C. GHELARDINI (2002). Inactivation of Gi proteins induces an antidepressant-like effect in the mouse forced-swimming test.. NEUROPHARMACOLOGY, vol. 43, pp. 457-465, ISSN:0028-3908 DOI

M. GUARNA; E. BIANCHI; A. BARTOLINI; C. GHELARDINI; N. GALEOTTI; BRACCI; L. C. NERI; D. SONETTI; G. STEFANO; (2002). Endogenous morphine modulates acute thermonociception in mice.. JOURNAL OF NEUROCHEMISTRY, vol. 80, pp. 271-277, ISSN:0022-3042 DOI

Ghelardini C.;Galeotti N.;Gualtieri F.;Romanelli M.;Bucherelli C.;Baldi E.;Bartolini A. (2002). DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, vol. 365, pp. 419-426, ISSN:0028-1298 DOI

C. GHELARDINI; N. GALEOTTI; M. CALVANI; L. MOSCONI; R. NICOLAI; A. BARTOLINI; (2002). ACETYL-L-CARNITINE INDUCES MUSCARINIC ANTINOCICEPTION IN MICE AND RATS. NEUROPHARMACOLOGY, vol. 43, pp. 1180-1187, ISSN:0028-3908 DOI

M. NICOLODI; N. GALEOTTI; C. GHELARDINI; A. BARTOLINI; F. SICUTERI (2002). CENTRAL CHOLINERGIC CHALLENGING OF MIGRAINE BY TESTING SECOND-GENERATION ANTICHOLINESTERASE DRUG. HEADACHE, vol. 42, pp. 596-602, ISSN:0017-8748 DOI

C. GHELARDINI; N. GALEOTTI; A. BARTOLINI (2002). AMITRIPTYLINE AND CLOMIPRAMINE ACTIVATE GI-PROTEIN SIGNALING PATHWAY IN THE INDUCTION OF ANALGESIA. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, vol. 365, pp. 1-7, ISSN:0028-1298 DOI

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (2002). ANTIHISTAMINE ANTINOCICEPTION IS MEDIATED BY GI-PROTEIN ACTIVATION. NEUROSCIENCE, vol. 109, pp. 811-818, ISSN:0306-4522 DOI

N. GALEOTTI; L. DI CESARE MANNELLI; G. MAZZANTINI; A. BARTOLINI; C. GHELARDINI (2002). MENTHOL: A NATURAL ANALGESIC COMPOUND. NEUROSCIENCE LETTERS, vol. 322, pp. 145-148, ISSN:0304-3940 DOI Accesso ONLINE all'editore

Carla Ghelardini;Nicoletta Galeotti;Fulvio Gualtieri;Dina Manetti;Corrado Bucherelli;Elisabetta Baldi;Alessandro Bartolini (2002). The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats. DRUG DEVELOPMENT RESEARCH, vol. 56, pp. 23-32, ISSN:0272-4391 DOI

N. GALEOTTI; C. GHELARDINI; I. GRAZIOLI; I. USLENGHI (2002). INDOMETHACIN, CAFFEINE AND PROCHLORPERAZINE ALONE AND COMBINED REVERT HYPERALGESIA IN VIVO MODELS OF MIGRAINE. PHARMACOLOGICAL RESEARCH, vol. 46, pp. 245-250, ISSN:1043-6618 DOI

C. Ghelardini; N. Galeotti; F. Gualtieri; D. Manetti; M.N. Romanelli; A. Bartolini (2002). The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats. In: COST Action D13 Workshop new molecules toward human health care, Firenze, 17-20 Aprile 2002, Università degli Studi di Firenze, pp. 52-52.

Nicoletta Galeotti; Alessandro Bartolini; Carla Ghelardini (2002). Role of Gi proteins in the antidepressant-like effect of amitriptyline and clomipramine.. NEUROPSYCHOPHARMACOLOGY, vol. 27, pp. 554-564, ISSN:0893-133X DOI Accesso ONLINE all'editore

N. GALEOTTI; C. GHELARDINI; L. DI CESARE MANNELLI; A. BARTOLINI (2001). ANTINOCICEPTIVE PROFILE OF THE NATURAL CHOLINESTERASE INHIBITOR HUPERZINE A. DRUG DEVELOPMENT RESEARCH, vol. 54, pp. 19-26, ISSN:0272-4391 DOI Accesso ONLINE all'editore

A Bartolini; E Beneforti; N Galeotti; C Ghelardini; M Zoppi (2001). Diagnostic method for algic pathologies. Numero: EP Patent 1,076,825,2001 Università degli Studi di Firenze

A Bartolini; N Galeotti; C Ghelardini; M Zoppi; E Del Bene; L Raimondi; E Beneforti (2001). Hypofunctionality of Gi proteins as aetiopathogenetic mechanism for migraine and cluster headache.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 133, pp. U31-U31, ISSN:0007-1188

N. GALEOTTI; C. GHELARDINI; M. ZOPPI; E. DEL BENE; L. RAIMONDI; E. BENEFORTI; A. BARTOLINI (2001). HYPOFUNCTIONALITY OF GI PROTEINS AS AETIOPHATOGENETIC MECHANISM FOR MIGRAINE AND CLUSTER HEADACHE. CEPHALALGIA, vol. 21, pp. 38-45, ISSN:0333-1024 DOI Accesso ONLINE all'editore

C. GHELARDINI; N. GALEOTTI; L. DI CESARE MANNELLI; A. CAPPELLI; M. ANZINI; A. BARTOLINI (2001). ANTIAMNESIC EFFECT OF THE TWO NOVEL K-OPIOID AGONISTS, VA-100 AND VA-101, IN THE MOUSE PASSIVE AVOIDANCE TEST. DRUG DEVELOPMENT RESEARCH, vol. 54, pp. 12-18, ISSN:0272-4391 DOI

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (2001). Involvement of potassium channels in amitriptyline and clomipramine analgesia.. NEUROPHARMACOLOGY, vol. 40, pp. 75-84, ISSN:0028-3908 DOI

C. GHELARDINI; N. GALEOTTI; G. MAZZANTI (2001). LOCAL ANAESTHETIC ACTIVITY OF MONOTERPENES AND PHENYLPROPANES OF ESSENTIAL OILS. PLANTA MEDICA, vol. 67, pp. 564-566, ISSN:0032-0943 DOI

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (2001). Differential prevention of morphine amnesia by antisense oligodeoxynucleotides directed against Gi-protein a subunits.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 133, pp. 267-274, ISSN:0007-1188 DOI

C. Ghelardini;N. Galeotti;L. Di Cesare Mannelli;G. Mazzanti;A. Bartolini (2001). Local anaesthetic activity of beta-caryophyllene.. IL FARMACO, vol. 56, pp. 387-389, ISSN:0014-827X DOI

N. GALEOTTI; C. GHELARDINI; L. DI CESARE MANNELLI; G. MAZZANTI; L. BAGHIROLI; A. BARTOLINI (2001). LOCAL ANAESTHETIC ACTIVITY OF (+) AND (-) MENTHOL. PLANTA MEDICA, vol. 67, pp. 174-176, ISSN:0032-0943 DOI Accesso ONLINE all'editore

C. Ghelardini; N. Galeotti; C. Lelli; A. Bartolini (2001). M1 receptor activation is a requirement for arecoline analgesia.. IL FARMACO, vol. 56, pp. 383-385, ISSN:0014-827X DOI Accesso ONLINE all'editore

Galeotti, Nicoletta; Ghelardini, Carla; Zoppi, M.; DEL BENE, Enrico; Raimondi, Laura; Beneforti, Elisabetta; Bartolini, Alessandro (2001). A REDUCED FUNCTIONALITY OF GI PROTEINS AS A POSSIBLE CAUSE FOR FIBROMYALGIA. THE JOURNAL OF RHEUMATOLOGY, vol. 28, pp. 2298-2304, ISSN:0315-162X Accesso ONLINE all'editore

A Bartolini; C Bellucci; N Galeotti; C Ghelardini; F Gualtieri; D Manetti (2001). Piperazine derivatives possessing nootropic activity. Numero: EP1118612, 2001. Università degli Studi di Firenze

R Pirisino;C Ghelardini;G Banchelli;N Galeotti;L Raimondi (2001). Methylamine and benzylamine induced hypophagia in mice: Modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels. BRITISH JOURNAL OF PHARMACOLOGY, vol. 134, pp. 880-886, ISSN:0007-1188 DOI

G. Banchelli; C. Ghelardini; L. Raimondi; N. Galeotti; R. Pirisino (2001). Selective inhibition of amine oxidases differently potentiate the hypophagic effect of benzylamine in mice.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 413, pp. 91-99, ISSN:0014-2999 DOI Accesso ONLINE all'editore

C. GHELARDINI; N. GALEOTTI; M. ROMANELLI; F. GUALTIERI; A. BARTOLINI (2000). PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9).. CNS DRUG REVIEWS, vol. 6, pp. 63-78, ISSN:1080-563X

C. GHELARDINI; N. GALEOTTI; L. DI CESARE MANNELLI; S. DEI; F. GUALTIERI; A. BARTOLINI (2000). AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES. DRUG DEVELOPMENT RESEARCH, vol. 51, pp. 191-196, ISSN:0272-4391 DOI

GHELARDINI C; GALEOTTI N; A. BARTOLINI (2000). Loss of muscarinic antinociception by antisense inhibition of M1 receptors.. BRITISH JOURNAL OF PHARMACOLOGY, vol. 129, pp. 1633-1640, ISSN:0007-1188 DOI

A Bartolini; L Di Cesare Mannelli; N Galeotti; C Lelli; S Livi; C Uslenghi; I Grazioli; C Ghelardini (2000). Un’aumentata liberazione di acetilcolina alla base dell’effetto analgesico indotto da proclorperazina. In: V. Gallai, G. Mazzotta, P. Sarchielli, A. Alberti. : Nuove prospettive nella terapia delle Cefalee, pp. 357-359, Firenze: V. Gallai, G. Mazzotta, P. Sarchielli, A. Alberti.

Dina Manetti; Carla Ghelardini; Alessandro Bartolini; Cristina Bellucci; Silvia Dei; Nicoletta Galeotti; Fulvio Gualtieri; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori (2000). 1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. In: 7th IBN SINA International Conference on pure and applied heterocyclic chemistry, Alexandria, Egypt, 25-28 March 2000, Chemistry Department Faculty of Science, pp. IL-51-IL-51.

C. GHELARDINI; N. GALEOTTI; A. BARTOLINI (2000). ANTINOCICEPTION INDUCED BY AMITRIPTYLINE AND IMIPRAMINE IS MEDIATED BY A2A-ADRENOCEPTORS. JAPANESE JOURNAL OF PHARMACOLOGY, vol. 82, pp. 130-137, ISSN:0021-5198 DOI

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (2000). ROLE OF 5-HT1A RECEPTORS IN A MOUSE PASSIVE AVOIDANCE PARADIGM. JAPANESE JOURNAL OF PHARMACOLOGY, vol. 84, pp. 418-424, ISSN:0021-5198 DOI Accesso ONLINE all'editore

C. Ghelardini; N. Galeotti; A. Bartolini (2000). Pro-cognitive activity induced in the rat by low doses of R-(+)-hyoscyamine.. FITOTERAPIA, vol. 71 Suppl 1, pp. S124-S130, ISSN:1971-551X DOI Accesso ONLINE all'editore

D. Manetti; C. Ghelardini; A. Bartolini; C. Bellucci; S. Dei; N. Galeotti; F. Gualtieri; M.N. Romanelli; S Scapecchi; E. Teodori (2000). 1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs. In: XVIth International Symposium on Medicinal Chemistry, Bologna, 18-22 Settembre 2000, Italian Chemical Society Division of Medicinal Chemistry, pp. 395-395.

C. GHELARDINI; N. GALEOTTI; A. BARTOLINI (2000). PHARMACOLOGICAL IDENTIFICATION OF SM-21, THE NOVEL SIGMA2 ANTAGONIST. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, vol. 67, pp. 659-662, ISSN:0091-3057 DOI

D. MANETTI; C. GHELARDINI; A. BARTOLINI; S. DEI; N. GALEOTTI; F. GUALTIERI; M. N. ROMANELLI; E. TEODORI (2000). Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 4499-4507, ISSN:0022-2623 DOI

C Ghelardini; N Galeotti; L Di Cesare Mannelli; M Nicolodi; F Sicuteri; C Uslenghi; I Grazioli; A Bartolini (2000). Effetto antiiperalgico della proclorperazina. In: V. Gallai, G. Mazzotta, P. Sarchielli, A. Alberti. Nuove prospettive nella terapia delle Cefalee, pp. 379-381, Firenze: V. Gallai, G. Mazzotta, P. Sarchielli, A. Alberti.

D. MANETTI; C. GHELARDINI; A. BARTOLINI; C. BELLUCCI; S. DEI; N. GALEOTTI; F. GUALTIERI; M.N. ROMANELLI; S. SCAPECCHI; E. TEODORI (2000). Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, pp. 1969-1974, ISSN:0022-2623 DOI

C. GHELARDINI; N. GALEOTTI; L. FANTETTI; F. GUALTIERI; S. SCAPECCHI; A. BARTOLINI; (1999). ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS. JAPANESE JOURNAL OF PHARMACOLOGY, vol. 81, pp. 34-37, ISSN:0021-5198 DOI

N. GALEOTTI; C. GHELARDINI; M.C.VINCI; A. BARTOLINI (1999). Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors. BRITISH JOURNAL OF PHARMACOLOGY, vol. 126, pp. 1214-1220, ISSN:0007-1188 DOI

C. GHELARDINI; N. GALEOTTI; G. SALVATORE; G. MAZZANTI (1999). LOCAL ANAESTHETIC AVTIVITY OF ESSENTIAL OIL OF LAVANDULA ANGUSTIFOLIA. PLANTA MEDICA, vol. 65, pp. 700-703, ISSN:0032-0943 DOI

C. GHELARDINI; I. MIZUMA; F. GUALTIERI; A. BARTOLINI; N. GALEOTTI; M. ROMANELLI; E. TEODORI (1999). Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity. ARZNEIMITTEL-FORSCHUNG, vol. 49 (I), pp. 483-488, ISSN:0004-4172

N. GALEOTTI; C. GHELARDINI; B. CALDARI; A. BARTOLINI (1999). EFFECT OF POTASSIUM CHANNEL MODULATORS IN MOUSE FORCED SWIMMING TEST. BRITISH JOURNAL OF PHARMACOLOGY, vol. 126, pp. 1653-1659, ISSN:0007-1188 DOI Accesso ONLINE all'editore

V. Marchese; N. Galeotti; C. Ghelardini; A. Bartolini; D. Manetti; S. Furukawa; A. Nitta; F. Gualtieri (1999). Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG-9. In: Society for Neuroscience 29th Annual Meeting, Miami Beach, Florida, 23-28 Ottobre 1999, Society of Neuroscience, pp. 1014-1014.

GHELARDINI C.; GALEOTTI N.; MATUCCI R.; BELLUCCI C.; GUALTIERI F.; CAPACCIOLI S.; QUATTRONE A.; BARTOLINI A. (1999). Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice. NEUROPHARMACOLOGY, vol. 38, pp. 339-348, ISSN:0028-3908 DOI

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; S. SCAPECCHI; A. BARTOLINI (1999). IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21. DRUG DEVELOPMENT RESEARCH, vol. 47, pp. 118-126, ISSN:0272-4391 DOI

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (1999). THE ROLE OF POTASSIUM CHANNELS IN ANTIHISTAMINE ANALGESIA. NEUROPHARMACOLOGY, vol. 38, pp. 1893-1901, ISSN:0028-3908 DOI Accesso ONLINE all'editore

D. Barlocco; G. Cignarella; D. Tondi; P. Vianello; S. Villa; A. Bartolini; C. Ghelardini; N. Galeotti; D. J. Anderson; T. A. Kuntzweiler; D. Colombo; L. Toma (1998). Mono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine: synthesis, activity, and modeling.. JOURNAL OF MEDICINAL CHEMISTRY, vol. 41, pp. 674-681, ISSN:0022-2623 DOI Accesso ONLINE all'editore

C. Ghelardini; N. Galeotti; F. Gualtieri; C. Bellucci; A. Bartolini (1998). Memory facilitation with atropine: a paradoxical effect. PHYTOTHERAPY RESEARCH, vol. 12, pp. S7-S9, ISSN:0951-418X DOI Accesso ONLINE all'editore

C Ghelardini; N Galeotti; A Bartolini (1998). Depressive behaviour induced by inhibition of mKv1.1 potassium channel expression by antisense ODN. JOURNAL OF NEUROCHEMISTRY, vol. 71, pp. S26-S26, ISSN:0022-3042

C Ghelardini; N Galeotti; A Ouattrone; A Bartolini (1998). Amnesia induced in mice by ICV treatment with an aODN to the M-1 receptor subtype gene. EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 10, pp. 156-156, ISSN:0953-816X

A Bartolini; C Ghelardini; N Galeotti; C Martini (1998). Analgesia induced by H-1 antagonists is not subjected to tolerance. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, vol. 358, pp. R118-R118, ISSN:0028-1298

E. GRATACOS; C. GHELARDINI; L.M. GHERARDINI; N. GALEOTTI; K. MURPHY; A. BARTOLINI; C. REGAN (1998). KV1.1 CHANNEL ANTISENSE ATTENUATES LEARNING AND MODULATION OF DENTATE POLYSIALYLATED NCAM. NEUROREPORT, vol. 9, pp. 2727-2731, ISSN:0959-4965 DOI

C. Ghelardini; N. Galeotti; S. Donaldson; A. Bartolini (1998). The antimigraine drug ergotamine is endowed with anti-hyperalgesic activity. PHYTOTHERAPY RESEARCH, vol. 12, pp. S10-S12, ISSN:0951-418X DOI Accesso ONLINE all'editore

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (1998). ROLE OF 5-HT4 RECEPTORS IN THE MOUSE PASSIVE AVOIDANCE TEST. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 286, pp. 1115-1121, ISSN:0022-3565 Accesso ONLINE all'editore

C. GHELARDINI; N. GALEOTTI; A. BARTOLINI (1998). Influence of potassium channel modulators on cognitive processes in mice. BRITISH JOURNAL OF PHARMACOLOGY, vol. 123, pp. 1079-1084, ISSN:0007-1188 DOI

C. GHELARDINI; N. GALEOTTI; F. GIULIANI; D. BARLOCCO; A. BARTOLINI (1998). ANTIAMNESIC ACTIVITY OF THE NICOTINIC AGONIST DBO-83 IN MICE. DRUG DEVELOPMENT RESEARCH, vol. 45, pp. 45-51, ISSN:0272-4391 DOI

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (1998). EFFECT OF PERTUSSIS TOXIN ON BACLOFEN-AND DIPHENHYDRAMINE- INDUCED AMNESIA. PSYCHOPHARMACOLOGY, vol. 136, pp. 328-334, ISSN:0033-3158 DOI Accesso ONLINE all'editore

C. GHELARDINI; N. GALEOTTI; A. BARTOLINI; S. FURUKAWA; A. NITTA; D. MANETTI; F. GUALTIERI (1998). Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9. JAPANESE JOURNAL OF PHARMACOLOGY, vol. 78, pp. 245-251, ISSN:0021-5198 DOI

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; V. MARCHESE; C. BELLUCCI; A. BARTOLINI (1998). Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 284, pp. 806-816, ISSN:0022-3565

C. GHELARDINI; N. GALEOTTI; A. BARTOLINI (1998). NO DEVELOPMENT OF TOLERANCE TO ANALGESIA BY REPEATED ADMINISTRATION OF H1 ANTAGONISTS. LIFE SCIENCES, vol. 63, pp. PL317-PL322, ISSN:0024-3205 DOI

C. GHELARDINI; N. GALEOTTI; D. BARLOCCO; A. BARTOLINI (1997). ANTINOCICEPTIVE PROFILE OF THE NEW NICOTINIC AGONIST DBO-83. DRUG DEVELOPMENT RESEARCH, vol. 40, pp. 251-258, ISSN:0272-4391

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (1997). 5-HT1A AGONISTS INDUCE CENTRAL CHOLINERGIC ANTINOCICEPTION. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, vol. 57, pp. 835-841, ISSN:0091-3057 DOI Accesso ONLINE all'editore

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; S. SCAPECCHI; A. BARTOLINI (1997). 3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION.. CNS DRUG REVIEWS, vol. 3, pp. 346-362, ISSN:1080-563X DOI

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; C. BELLUCCI; D. MANETTI; A. GIOTTI; P. MALMBERG; A. GALLI; A. BARTOLINI (1997). Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 282, pp. 430-439, ISSN:0022-3565

N. MEIRI; C. GHELARDINI; G. TESCO; N. GALEOTTI; D. DAHL; D. TOMSIC; S. CAVALLARO; A. QUATTRONE; S. CAPACCIOLI; A. BARTOLINI; D. ALKON (1997). Reversible antisense inhibition of Shaker-like Kv1.1 potassium channel expression impairs associative memory in mouse and rat. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 94, pp. 4430-4434, ISSN:0027-8424 DOI

C. GHELARDINI; A. BARTOLINI; N. GALEOTTI; C. BELLUCCI; S. DEI; F. GUALTIERI (1997). In vitro characterization of a novel, potent and selective M3 antagonist. LIFE SCIENCES, vol. 61, pp. 1217-1226, ISSN:0024-3205 DOI

GHELARDINI C; GALEOTTI N; PECORI VETTORI A; CAPACCIOLI S; QUATTRONE A; A. BARTOLINI (1997). Effect of K+ channel modulation on mouse feeding behaviour. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 329, pp. 1-8, ISSN:0014-2999 DOI

N Meiri; C Ghelardini; G Tesco; N Galeotti; D Dahl; D Tomsic; S Cavallaro; A Quattrone; S Capaccioli; A Bartolini; DL Alkon (1997). Antisense to the rodent Shaker-like potassium channel Kv1.1 alters memory without effecting LTP. BIOPHYSICAL JOURNAL, vol. 72, pp. TUAM8-TUAM8, ISSN:0006-3495

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; C. BELLUCCI; D. MANETTI; P. BOREA; A. BARTOLINI (1997). Antinociceptive property of the nicotinic agonist AG4 in rodents. DRUG DEVELOPMENT RESEARCH, vol. 41, pp. 1-9, ISSN:0272-4391 DOI

N. GALEOTTI; C. GHELARDINI; E. TEODORI; F. GUALTIERI; A. BARTOLINI (1997). ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST. PHARMACOLOGICAL RESEARCH, vol. 36, pp. 59-67, ISSN:1043-6618

M Nicolodi; F Sicuteri; C Ghelardini; N Galeotti; A Bartolini (1997). Proposal of an animal model to test specific acute drugs for migraine attacks. CEPHALALGIA, vol. 17, pp. 400-400, ISSN:0333-1024

N. Galeotti ; C. Ghelardini ; L. Papucci ; S. Capaccioli ; A. Quattrone ; A. Bartolini (1997). An antisense oligonucleotide on the mouse Shaker-like potassium channel Kv1.1 gene prevents antinociception induced by morphine and baclofen. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 281, pp. 941-949, ISSN:0022-3565

V. Marchese; C. Ghelardini; N. galeotti; C. Bellucci; D. Manetti; F. Gualtieri; P.A.Borea; A. Bartolini (1997). Antinociceptive and antiamnesic properties of the nicotinic agonist AG-4. In: 27th Annual Meeting Society for neuroscience, New Orleans, LA, 25-30 Ottobre 1997, Society of Neuroscience, pp. 216-216.

C. Ghelardini; N. Galeotti; M. Nicolodi; S. Donaldson; F. Sicuteri; A. Bartolini (1997). Involvement of central cholinergic system in antinociception induced by sumatriptan in mouse.. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY RESEARCH, vol. 17, pp. 105-109, ISSN:0251-1649 Accesso ONLINE all'editore

C. Ghelardini; N. Galeotti; A. Bartolini (1997). Caffeine induces central cholinergic analgesia.. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, vol. 356, pp. 590-595, ISSN:0028-1298 DOI Accesso ONLINE all'editore

GALEOTTI N.; GHELARDINI C.; S. CAPACCIOLI; QUATTRONE A.; NICOLIN A.; BARTOLINI A. (1997). Blockade of clomipramine and amitriptyline analgesia by an antisense oligonucleotide to mKv1.1, a mouse Shaker-like potassium channe. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 330, pp. 15-25, ISSN:0014-2999 DOI

C. GHELARDINI; N. GALEOTTI; L. FANTETTI; F. GUALTIERI; S. DEI; S. SCAPECCHI; A. BARTOLINI (1997). Central muscarinic antinociception induced by ET-142 and SS-20 in rodents. DRUG DEVELOPMENT RESEARCH, vol. 42, pp. 26-34, ISSN:0272-4391 DOI

C.GHELARDINI; N.GALEOTTI; A.PECORI VETTORI; S.CAPACCIOLI; A.QUATTRONE; A.BARTOLINI (1997). Effects of potassium channels modulation on mouse feeding behaviour.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 329, pp. 1-8, ISSN:0014-2999, Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598:

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; M. ROMANELLI; A. BARTOLINI (1997). ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM. PHARMACOLOGICAL RESEARCH, vol. 35, pp. 141-147, ISSN:1043-6618 DOI

C Ghelardini; N Galeotti; S Capaccioli; A Quattrone; A Bartolini (1997). Amnesia induced by ICV treatment with aODN to the K+ channel mKv1.1 gene. JOURNAL OF NEUROCHEMISTRY, vol. 69, pp. S251-S251, ISSN:0022-3042

N. GALEOTTI; C. GHELARDINI; A. BARTOLINI (1996). PIRACETAM AND ANIRACETAM ANTAGONISM OF CENTRALLY ACTIVE DRUG-INDUCED ANTINOCICEPTION. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, vol. 53, pp. 943-950, ISSN:0091-3057 DOI Accesso ONLINE all'editore

GALEOTTI N; C. GHELARDINI; BARTOLINI A (1996). Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception.. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 308, pp. 125-133, ISSN:0014-2999 DOI

C. GHELARDINI; N. GALEOTTI; M. NICOLODI; F. SICUTERI; A. BARTOLINI; M. FIGINI; A. IMPERATO; G. GESSA (1996). THE CENTRAL CHOLINERGIC SYSTEM HAS A ROLE IN THE ANTINOCICEPTION INDUCED IN RODENTS AND GUINEA-PIGS BY THE ANTIMIGRAINE DRUG SUMATRIPTAN. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 279, pp. 884-890, ISSN:0022-3565

C. Ghelardini; N. Galeotti; F. Casamenti; P. Malmberg-Aiello; G. Pepeu; F. Gualtieri; A. Bartolini (1996). Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8. LIFE SCIENCES, vol. 58, pp. 2297-2309, ISSN:0024-3205 DOI

C. GHELARDINI; N. GALEOTTI; F. GUALTIERI; S. SCAPECCHI; A. BARTOLINI (1996). R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER. PHYTOTHERAPY RESEARCH, vol. 10, pp. 62-64, ISSN:0951-418X

C. GHELARDINI; A. BARTOLINI; N. GALEOTTI; E. TEODORI; F. GUALTIERI (1996). S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo. LIFE SCIENCES, vol. 58, pp. 991-1000, ISSN:0024-3205 DOI

N. Galeotti; F. Follegatti; S. Donaldson; D. Manetti; C. Ghelardini (1996). Valutazione dell'attività antinocicettiva dell'agonista nicotinico AG-4 in topi e ratti. In: Società Italiana di Neuroscienze V Convegno Nazionale, Pisa, 12-14 Dicembre 1996, Società Italiana di Neuroscienze, pp. D10-D10.

Galeotti N; Ghelardini C; Quattrone A; Schiavone N; Capaccioli S; Bartolini A (1996). Baclofen antinociception is prevented by ICV injection of pertussis toxin and by an aODN to the mKv1.1 potassium channel... In: 3rd International GABA(B) Symposium., BAIA PARAELIOS, ITALY, SEP 21-25, 1996, Elsevier B.V., vol. 8, pp. 135-140.

C. Ghelardini;M. Baldini;N. Galeotti;F. Gualtieri;E. Teodori;A Bartolini (1995). Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype?. LIFE SCIENCES, vol. 56, pp. 1040-1040, ISSN:0024-3205 DOI

N Galeotti; C Ghelardini; A Bartolini (1995). Involvement of the serotoninergic system in the analgesic effect of tricyclic antidepressants. BEHAVIOURAL PHARMACOLOGY, vol. 6, pp. 20-20, ISSN:0955-8810

C Ghelardini; N Galeotti; L Fantetti; A Bartolini (1995). Buspirone and gepirone: two anxiolytic drugs endowed with antinociception mediated by the cholinergic system. BEHAVIOURAL PHARMACOLOGY, vol. 6, pp. 42-43, ISSN:0955-8810

Nicoletta Galeotti; Carla Ghelardini; Marco Baldini; Lisa Gherardini; Fulvio Gualtieri; Silvia Dei; Alessandro Bartolini (1995). S-(-)-ET126: a potent and selective M1 antagonist. LIFE SCIENCES, pp. 1051-1051, ISSN:0024-3205

F. GUALTIERI; C. BOTTALICO; A. CALANDRELLA; S. DEI; M. GIOVANNONI; S. MEALLI; M. ROMANELLI; S. SCAPECCHI; E. TEODORI; N. GALEOTTI; C. GHELARDINI; A. GIOTTI; A. BARTOLINI (1994). Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters. JOURNAL OF MEDICINAL CHEMISTRY, vol. 37, pp. 1712-1719, ISSN:0022-2623 DOI

A BARTOLINI; L FANFANI; N GALEOTTI; C GHELARDINI; A GIOTTI; P MALMBERG-AIELLO; P MEONI (1994). Antagonism by piracetam of baclofen antinociception. BRITISH JOURNAL OF PHARMACOLOGY, vol. 111, pp. P95-P95, ISSN:0007-1188

Galeotti, N; Fanfani, L; Meonin, P; Ghelardini, C; Giotti, A; Gualtieri, F; Romanelli, Mn; Bartolini, A (1993). Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory. In: XXI International Congress of Neurovegetative Research, Elsevier, vol. 43, pp. 78-79.

Nicoletta GALEOTTI

Biography

1989: Degree, Pharmacy, University of Pisa, summa cum laude

1993: Specialty School, Experimental Pharmacology, University of Florence, summa cum laude

1999: PhD, Pharmacology and Toxicology, University of Florence

Nicoletta GALEOTTI

Curriculum

Education and Training

2000: National Course on New Perspective for Headache Therapy

1999: Ph.D. in Pharmacology and Toxicology, University of Florence

1995: Course on Biotechnologies applied to the study of heterotrimeric G proteins

1993: Specialty School in Pharmacology summa cum laude, University of Florence

1989: Degree summa cum laude in Pharmacy, University of Pisa

Work Experience

2015 to date: Associate Professor, University of Florence

2006-2012: Member of the Board of the Department of Pharmacology, University of Florence

2004 to date: Member of the Scientific Committee of the Department of Pharmacology, University of Florence

2000-2015: Researcher, University of Florence

1998-1999: research fellow Price Foundation, Washington DC, USA Laboratory of Cellular Biology, University of Pisa

1992-1994: research fellow at University of Florence, awarded by Fidia Spa, Abbot Laboratories

Teaching experience

2024 to date: Professor of General Pharmacology, University of Florence

2017 to date: Professor of Pharmacology and Pharmacognosy; II level Master (University of Siena, University of Milan)

2000 to date: Professor of Pharmacology and Pharmacognosy, University of Florence

2003-2004: Professor of Pharmacy, Specialty School in Hospital Pharmacy, University of Florence

2001: Professor of Pharmacology, University of Odense (Denmark), Socrates Project

Editorial activity:

2023: Frontiers in Pharmacology, Editorial Board Member

2022: Biomedicines, Special Issue Guest Editor

2021: Biomedicine, Editorial Board Member

2020: Neuropharmacology, Editorial Board Member

2017: EC Psychology and Psychiatry, Editorial Board Member

2015: SM Journal of Depression Research and Treatment, Editorial Board Member

2014: translation and revision of “Fundamentals of Pharmacognosy and Phytotherapy”, second edition, By Heinrich, Barnes, Gibbons, Williamson, Ed. Churchill Livingstone

2013: ad hoc reviewer for FIRB project - Futuro in Ricerca 2013;

2013: Pharmacognosy Journal (Elsevier), Editorial Board Member

2012: ad hoc reviewer for PRIN project 2010-2011

2006: pharmacological reviewer for ESCOP monographies

1998 to date: Ad hoc reviewer for international scientific journals

Awards and prizes:

2000: Aventis Prize

1999: award Pharmacological Research Maurizio Soma

1993-1999: travel grants from the Italian Society of Pharmacology; invited speaker

1993: award from LPB

1992: award from Fidia Spa

Nicoletta GALEOTTI

Interest

Investigation into cellular and molecular bases of microglia-mediated neuroinflammation
Study of the cellular senscence and aging
Investigation into epigenetic and molecular alterations in neuropathic pain of central and peripheral origin to identify innovative therapeutic perspectives
Antisense strategy applied to neurodegenerative disorders
Study of behavioural phenotype induced by natural compounds in neuropathic pain and neurodegenerative disorders
Investigation into the neuron-glia communication pathways in demyelination and neurodegeneration

Nicoletta GALEOTTI

Note

Thesis topics

- investigation of natural compounds able to promote analgesic and neuroregenerative activity

- study of neuron-glia communication pathways in demyelination and neurodegeneration

- pathological role of microglial senescence in neurodegenerative disorders

- identification of innovative anti-senescence therapies

- antisense strategy applied to neurodegenerative disorders with development of neuropathic pain

Area riservata