Paola TURANO

Ruolo attuale:: Professore Ordinario
SSD:: CHEM-03/A - Chimica generale e inorganica
Afferenza organizzativa:: Dipartimento di Chimica 'Ugo Schiff' - DICUS

Recapiti

	0554574266 - 0554573316
	paola.turano(AT)unifi.it

Paola TURANO

Orario di ricevimento (aggiornato al 29/08/2022)

Venerdì dalle 14 alle 15, stanza 359 del Dipartimento di Chimica.

Si prega di inviare una e-mail per controllare la disponibilità del docente nei giorni immediatamente precedenti.

Paola TURANO

Biografia

Paola Turano è professore ordinario di Chimica Generale e Inorganica all'Università di Firenze. La sua attività di ricerca è principalmente dedicata all'NMR in Life Sciences. Ha una lunga esperienza nello sviluppo e nell'applicazione di metodi NMR a sistemi inorganici di rilevanza biologica, con particolare attenzione alle proteine eme e alle ferritine. Dal 2008 ha ampliato il suo interesse di ricerca includendo la metabolomica basata sull'NMR. In questo campo ha portato un contributo originale nel settore della pre-analisi (sviluppato attraverso i progetti FP7 SPIDIA e H2020 SPIDIA4P), che l'ha portata al coinvolgimento nei comitati tecnici CEN e ISO per lo sviluppo di standard pre-analitici per la metabolomica. Dal 2020 è inoltre in corso una ricerca attiva sulla profilazione di metaboliti e liproproteine in campioni di siero o plasma di soggetti COVID-19.

Paola TURANO

Curriculum

Place & date of birth/Luogo e data di nascita: Firenze 05/07/1964

Nationality/Nazionalità: Italian/Italiana

Address/Indirizzo:

CERM – Via. Sacconi, 6

Dipartimento di Chimica Ugo Schiff – Via della Lastruccia 3-13

Università degli Studi di Firenze

50019 Sesto Fiorentino (Firenze) Italia

e-mail:turano@cerm.unifi.it,paola.turano@unifi.it

Education/Formazione:

1993 – Ph.D. in Chemical Sciences/Dottorato di Ricerca in Scienze Chimiche – Università di Firenze

1989 – Degree in Chemistry/Laurea in Chimica (110/110 cum laude) – Università di Firenze

Professional Appointments/Incarichi professionali

September 2021-present Full professor – Univ. of Florence

November2002–August 2021 Associate Professor – Univ. ofFlorence

October1997–October2002 Researcher at the Faculty of Sciences – Univ. of Florence

June1996–September1997 Research contract –Dept. of Chemistry –Univ. of Florence

May1994-April1996 Postdoctoral fellowship – Univ. ofFlorence

November1993-January1994 Visiting Associate in Chemistry – California Institute of Technology

Management activities (University of Florence)/Attività di gestione (Università di Firenze)

Support for the management of research centers and services:

2023-ongoing President, Magnetic Resonance Center (CERM)

2022-2024 Member of the Steering and Self-evaluation Committee, Department of Chemistry

2017-2023 Member of the Scientific Council of the Magnetic Resonance Center (CERM)

2017-2023 Scientific Director and President of the Scientific Committee, da Vinci European Biobank

2013-2015 Member of the Board of the Chemistry Department

2010-2014 Member of the Scientific Council of the Magnetic Resonance Center (CERM)

1998-2000 Member of the Board of Chemistry Department

Coordination of teaching activities:

2016-2024 Chair of the Bachelor's Degree Course in Biotechnology

2015-2022 Chair of the Master's Degree Course in Molecular Biotechnology

2001-ongoing Member of the Board of Teachers of the International Doctorate in Structural Biology / Mechanistic and Structural Systems Biology

2004-ongoing Teaching Committee, Master's Degree in Molecular Biotechnology

2001-ongoing Teaching Committee, Bachelor's Degree in Biotechnology (delegate for the biomolecular curriculum)

Offices held/Incarichi presso società o istituzioni scientifiche

National/Nazionali:

2024-ongoing Member of the Executive Board, Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine

2016-2019 Vice-Chair, Gruppo Italiano Discussione Risonanze Magnetiche(GIDRM)

2015-2016 Treasurer, Gruppo Italiano Discussione Risonanze Magnetiche (GIDRM)

2014-2015 Vice-Chair, Gruppo Italiano Discussione Risonanze Magnetiche (GIDRM)

2014-2017 Chair of the scientific committee, da Vinci EuropeanBiobank of the FiorGen Foundation

2009-2013 Scientific committee member, da Vinci European Biobank of the FiorGen Foundation

International/Internazionali

2024-ongoing Member of the SBIC nomination committee

2012-2014 Chair, Division of Chemistry in Life Sciences ofEuCheMS

2008-2012 Council member, Society of Biological Inorganic Chemistry (SBIC)

Awards/Premi

“GIDRM/GIRM Gold Medal 2023”

“Raffaello Nasini Medal 2003” of the Inorganic Chemistry Division of the Italian Chemical Society

European CEN-CENELEC Project Award 2021 (Project Award to the SPIDIA4P consortium)

Research funding/Finanziamenti (bandi competitivi)

Project/Progetto	Duration/Durata (months/mesi)	Role/Ruolo
Predictive modeling of Omics biomarkers in temporal lobe Epilepsy: a comprehensive multidisciplinary and Translational Approach from rodents to humans (POETA) – PRIN 2022	24	PI of Research Unit
A Flexible antibody-drug conjugate Approach for Innovative antiviral THerapy (FAITH) – PRIN 2020	36	PI of Research Unit
COMETA - Studio del fingerprint metabolomico dei pazienti affetti da Covid 19 per un accurato inquadramento diagnostico, prognostico e terapeutico - BANDO RICERCA COVID-19 TOSCANA	24	PI of Research Unit
Sviluppo di nanodispositivi a base di ferritina per il trasporto mirato di farmaci e sonde per imaging - Fondazione Cassa di Risparmio di Firenze 2020.1519	12	PI
Advanced mass spectrometry tools for cancer research: novel applications in proteomics, metabolomics and nanomedicine (AIRC - Fondazione CR Firenze Multi - user Equipment Program Call for Proposals 2016	24	PI of Research Unit
SPIDIA4P “SPIDIA for personalized Medicine Standardization of Generic Preanalytical procedures for In-vitro diagnostics for personalized medicine” H2020	48	PI of Research Unit
Valutazione del tempo di vita dei campioni in biobanche di materiale biologico - Ente CRF 2013.0494	18	PI of Research Unit
Progetto RISE - Regione Toscana PAR FAS 2007-2013 – Realizzazione Centri di Competenza	36	PI of Research Unit
Farmaci innovativi per Malattie Neurodegenerative - FINDING - POR CREO FESR 2007-2013	24	PI of Research Unit
Controllo Qualità di campioni biologici conservati in biobanca – Ente CRF 2011.1073	12	PI
Realizzazione laboratori di biologia cellulare e molecolare (BioLab) - Ente CRF 2008.2026	12	PI
SPIDIA "Standardisation and improvement of generic pre-analytical tools and procedures for in-vitro diagnostics" HEALTH-F5-2008-222916	54	PI of Research Unit
"Ingegneria proteica e caratterizzazione strutturale di eme proteine per applicazioni bioelettroniche" - Progetto Finalizzato Biotecnologie	24	PI

Invited Talks/Interventi su invito

Conferences /congressi:

- 17th European Biological Inorganic Chemistry Conference (EuroBIC 17), Münster (DE), August 25-29, 2024.

- Experimental and computational molecular biology, Florence (Italy) May 9, 2024

- 50^th National Congress on Magnetic Resonance, Roma (Italy), September 6-8, 2023 GIDRM/GIRM MEDAL LECTURE

- XIII International Conference NMR a tool for Biology, Paris (France), May 15-17, 2023. PLENARY

- Joint Italian-French meeting on magnetic resonance, Milano (Italy), September 27-30, 2022. PLENARY

- Biobanking applications in clinical research (online event), November 19, 2021.

- National Meeting of the Italian Chemical Society, Division of Biological Systems (virtual meeting), September 14-23, 2021. KEYNOTE

- 11th International Conference on Porphyrins and Phthalocyanines (ICPP-11), (virtual meeting), June 28-July 3, 2021.

- Meeting of BBMRI.at/it/cy/cz - Strengthening Synergies, Graz (Austria), December 9-11, 2019.

- Bruker Symposium at the Jahrestagung der DGKL, Magdeburg (Germany), September 25-27, 2019.

- 19th International Conference on Biological Inorganic Chemistry (ICBIC-19), Interlaken (Switzerland), August 11-16, 2019.

- 15th International Symposium on Applied Bioinorganic Chemistry (ISABC15), Nara (Japan) June 2–5, 2019.

- Nuclear Magnetic Resonance for Nanomedicine and Metabolomics Research – NMR 4 NMR Kick-off Meeting, Padova (Italy), February 21, 2019.

- Past, present and future of inorganic chemistry in italy: a path defined by the winners of the Nasini prize, February 11-12, 2019.

- Giornata Nazionale di BBMRI.it, Roma (Italy), January 10, 2019.

- 14th European Biological Inorganic Chemistry Conference (EuroBIC 14), Birmingham (UK), August 26-30, 2018. KEYNOTE

- 10th International Conference on Porphyrins and Phthalocyanines (ICPP-10), Munich (Germany), July 1-6, 2018

- Cecam Workshop Physiological role of ions in the brain: towards a comprehensive view by molecular simulation, Pisa (Italy) May 21-23, 2018

- NMR Day: HR-MAS NMR, metabolomics and multivariate analysis, Milano (Italy) 6 June, 2017.

- NMR & MS in metabolomica, Padova (Italia), February 3, 2017.

- NMR Pharma Day, IRBM Science Park, Pomezia (RM; Italy) November 16 2016.

- 6th EuCheMS Chemistry Congress: Chemistry, Seville (Spain), September 11-15,2016. KEYNOTE

- 9th International Conference on Porphyrins and Phthalocyanines (ICPP-9), Nanjing (China), July 3-8,2016.

- 3rd Jena HHDP Symposium, Jena (Germany), May 25-27,2016.

- Biobanking National Infrastructures meeting, Nice (France), May 17-19,2016.

- XIII International Symposium on Inorganic Biochemistry, Karpacz (Poland), September 1-6,2015.

- IV International Conference on Cofactors (ICC04), Parma (Italy), August 25-28,2014.

- 12th European Biological Inorganic Chemistry Conference (EuroBIC 12), Zürich (Switzerland), August 24-262014. PLENARY

- 8th International Conference on Porphyrins and Phthalocyanines (ICPP-8), Istanbul (Turkey), June 22-27,2014.

- XII International Symposium on Inorganic Biochemistry - Collaboration and Beyond, Wrocław (Poland), August 28- September 1, 2013. PLENARY

- Italian Meeting on Porphyrins and Phtalocyanines (IMPP-1), Roma (Italy), July 1-3,2013.

- 5th European Conference on “Chemistry for Life Sciences” (5th ECCLS), Barcelona (Spain), June 10-12, 2013. PLENARY

- The quality of molecular methods in the age of personalized medicine, Florence (Italy), May 18,2013.

- Metabolomics in clinics, Milan (Italy), November 30,2012.

- Convegno nazionale della Divisione di Chimica dei Sistemi Biologici, Napoli (Italy), September 24-25,2012.

- XLI National Congress on Magnetic Resonance, Pisa (Italy) September 17-19,2012.

- 7th International Conference on Porphyrins and Phthalocyanines (ICPP-7), Jeju (Korea), July 1-6,2012.

- 221st ECS Meeting, Seattle (WA, USA), May 6-10,2012.

- ACS 241st National Meeting, Anaheim (CA, USA), March 27 – 31,2011.

- 3rd EuCheMS Chemistry Congress: Chemistry - the Creative Force, Nürnberg (Germany), August 29 agosto – September 2, 2010.

- 6th International Conference on Porphyrins and Phthalocyanines (ICPP-6), Albuquerque (USA), July 4-9,2010.

- Early stage drug discovery, Berlin Buch (Germany), May 27-28,2010.

- N.M.R: a tool for biology IX, Paris (France), January 25-27,2010. PLENARY

- CEUM 2009, Cluj-Napoca (Romania), October 4-6,2009.

- 3rd European Conference on Chemistry in Life Sciences, Frankfurt am Main (Germany), September 2-5,2009.

- ICBIC 14, Nagoya (Japan), July 25-30,2009.

- Gordon Research Conference - Metals in Biology Ventura (CA, USA), January 25-30,2009.

- EUROBIC9, Wroclaw (Poland), September 2-6,2008.

- ACS 236th National Meeting, Philadelphia (PA, USA), August 17 – 21,2008.

- 5th International Conference on Porphyrins and Phthalocyanines (ICPP-5), Moscow (Russia), July 6-11,2008.

- XXXVII National Congress on Magnetic Resonance, Verbania Pallanza (Italy), September 12-15,2007. KEYNOTE

- NMR solid state Bruker user’s meeting, Florence (Italy), April 19,2007.

- VI International Symposium on Metals, Environment and Health, Szklarska Poreba (Poland), September 6-9,2006.

PLENARY

- 4th International Conference on Porphyrins and Phthalocyanines (ICPP-4), Roma (Italy), July 2-7,2006.

- COST D21 Final Workshop on “Metalloenzymes and Chemical Biomimetics”, Leuven (Belgium), May 25-28,2006.

- XXXIII National Congress of the Inorganic Chemistry Division of the Italian Chemical Society, Siena (Italy), July 11-16,2005.

- 3rd International Conference on Porphyrins and Phthalocyanines (ICPP-3), New Orleans (USA), July 11-16,2004.

- 11th International Conference on Biological Inorganic Chemistry (ICBIC), Cairns (Australia), July 19-23,2003.

- National Meeting of the Italian Chemical Society, Division of Inorganic Chemistry Turin (Italy), June 22-25,2003. NASINI AWARD LECTURE

- 7th FIGIPS Meeting in Inorganic Chemistry, Lisboa (Portugal), June 11-15,2003.

- 10th Chianti Workshop on Magnetic Resonance, San Miniato (Pisa, Italy), May 25-30,2003.

- Sapio Meeting 2003, Florence (Italy), May 10, 2003.

- COST D21 Working Group meeting “Structural and Spectroscopic Studies of Metalloproteins and Electron Transfer Proteins”, Marseille (France), October 3-6,2002.

- 2nd International Conference on Porphyrins and Phthalocyanines (ICPP-2), Kyoto (Japan), June 30–July 5, 2002.

- Progress meeting of EEC METALBIOREDUCTION RTD project, Marseilles (France), June 11-12,2001.

- SAPIO NMR/MRI Conferences 2001 “NMR in Puglia: ambiente, alimentazione, salute” Bari (Italy), June 1,2001.

- Tavola Rotonda “La biologia strutturale e le biotecnologie” Collaretto Giacosa (Turin - Italy), February 14,2001.

- On the occasion of the Laurea honoris causa to K. Wuthrich, Siena (Italy), March 20,1997.

- IV Convegno Nazionale di Chimica dei Sistemi Biologici, Siena (Italy), September 24-26,1996.

- Workshop: The Dynamics of Protein Structure, San Miniato (Pisa - Italy), September 14-15,1996.

- 4th Joint Greek-ltalian Meeting on Chemistry of Biological Systems and Molecular Chemical Engineering, Turin (Italy), June1-3, 1996.

- Convegno Nazionale di Risonanze Magnetiche, Rome (Italy), October 21-23, 1992.

Schools/Scuole

-Scuola Nazionale di Bioinorganica, SCI, Caserta (Italy) 27-30 giugno 2023.

-NMR School – Advanced NMR, GIDRM/Università di Torino, Turin (Italy) 18-22 luglio 2022.

-NMR School – Advanced NMR, GIDRM/Università di Torino (via web), 20-23 luglio 2020.

-3rd Summer School of Medicinal Chemistry, Santa Margherita di Pula, Cagliari (Italy) August 28–September 1, 2017.

-Schulich Winter School, Frontiers in Inorganic Chemistry, Haifa (Israel), December 1-3, 2015.

-Summer Inorganic Medicinal Chemistry School, Cagliari (Italy), September 28-October 1, 2015.

-Summer School of Bioinorganic Chemistry, Cagliari (Italy), September 8-11, 2013.

-Scuola Nazionale di Chimica Bioinorganica, Siena (Italy), July 3-6, 2011.

-IX Laboratorio di Metodologie Sintetiche in Chimica Farmaceutica, Siena (Italy), February 14-18, 2010.

-Scuola Nazionale di Chimica Bioinorganica per Dottorandi, San Miniato (Pisa, Italy), June 24-28,2002.

-Metodologie in Biologia Strutturale, Collaretto Giacosa, Turin (Italy), February 12-15, 2001.

- Modern Techniques in Industrial Biology: Metodi per la determinazione della struttura delle proteine”, Turin (Italy), January 31–February 4, 2000.

Seminars/Seminari:

- ISA-Lyon, April 6, 2018

- Università di Perugia, May 3,2016

- Università di Roma - La Sapienza, April 7,2017

- Scuola Normale Superiore di Pisa, October 1,2014

- Medical University of Graz, October 10, 2012.

- University of Arizona, July 13,2010.

- University of Bayreuth, November 29,2006.

- Institut Pasteur, Paris, June 21,2005.

- Siena Biotech, Siena, March 16,2005.

- Institut de Chimie Minérale et Analitique, Université de Lausanne, April 16,1996.

- Institut für Anorganische Chemie, Universitat Basel, April 15,1996.

- Fachbereich Chemie, Universität Dortmund, February 1,1996.

Conference and school organization/Organizzazione di congressi e scuole

- Member of the Organizing Committee 51^th National Congress on Magnetic Resonance, Firenze, September 4-6, 2024

- Member of the Organizing Committee Italian Metabolomics Network General Meeting Genova, November 9-10, 2023

- Session Chair (T13 – Metals in biology) 44th International Conference on Coordination Chemistry (ICCC2022) Rimini, August 28-September 2, 2022.

- Member of the Scientific Committee Advances in NMR and MS Based Metabolomics, Lucca, November 20-22, 2019.

- Member of the Scientific Committee XLVIII National Congress on Magnetic Resonance, L’Aquila, September 11-13 2019.

- Member of the Scientific Committee - GIDRM day “Metabolomics in cancer”, Florence, November 28, 2018.

- Member of the Scientific Committee XLVII National Congress on Magnetic Resonance, Torino, September 19-21 2018.

- Member of the Scientific Committee - Workshop “CHANCES” - Crystallography And Nmr in Complementary Structural Investigations, Florence, September 4th, 2018.

- Member of the Scientific Committee - Advances in NMR and MS Based Metabolomics, Padova, November 14-16, 2017.

- Member of the Scientific Committee - XLVI National Congress on Magnetic Resonance, Fisciano (Salerno), September 27-29 2017.

- Member of the Scientific Committee - XLV National Congress on Magnetic Resonance, September 5-7 2016, Modena.

- Organizer - NMR Day: “Industrial applications of proteins: what role for NMR?”, Firenze, June 15 2016.

- Member of the Scientific Committee - XLIV National Congress on Magnetic Resonance, Roma, September 28-30 2015.

- Member of the Scientific Committee - XLIII National Congress on Magnetic Resonance, Bari, September 22-24 2014.

- Chair, EMBO Practical Course, Solution and solid-state NMR of paramagnetic molecules, Sesto Fiorentino (Italy) 13–19 July 2014

- Session organizer, 8th International Conference on Porphyrins and Phthalocyanines (ICPP-8), Istanbul (Turkey), June 22-27, 2014.

- Organizer of the “12th Chianti/INSTRUCT Workshop on BioNMR”, Montecatini (Italy), June 17-22, 2012.

- Session organizer, 7th International Conference on Porphyrins and Phthalocyanines (ICPP-7), Jeju (Korea), July 1-6, 2012.

- Member of the organizing Committee of “NMR to lay the bricks for molecular systems biology”, Montecatini Terme, Italy, December 14-18, 2008

- Session organizer of “2nd European Conference on Chemistry for Life Sciences”, Wroclaw, Poland, September 4-8 2007.

- Organizer of “Second EuCheMS School on protein Chemistry”, Alba di Canazei, January 15-20, 2006.

- Member of the Organizing Committee of “4th International Conference on Porphyrins and Phthalocyanines (ICPP-4), Roma (Italy), July 2-7, 2006.

- Member of the Organizing Committee of “First European Conference on Chemistry for Life Sciences”, Rimini, October 4-8, 2005.

- Organizer of “First FECS School on Protein Chemistry”, Brixen, January 9-14, 2005.

- Member of the Organizing Committee of “1st International Meeting on: Genome Based Drug Discovery”, Florence, March 22-27, 2004.

- Organizer of “X Chianti Workshop of Magnetic Resonance, Nuclear and Electron Relaxation”, San Miniato, Pisa, May 25 – 30, 2003.

- Organizer of “IX Chianti Workshop of Magnetic Resonance, Nuclear and Electron Relaxation”, Tirrenia, Pisa, May 26 – June 1, 2001.

- Organizer of the “VIII Chianti Workshop of Magnetic Resonance, Nuclear and Electron Relaxation”, San Miniato, Pisa, May 30 – June 5, 1999

- Member of the Organizing Committee of "NMR for the development of Science and Technology", Florence, June 7-8, 1996.

Editorial activities/Attività editorial2017- Section Board Member for 'Molecular Biophysics' - International Journal of Molecular Sciences2016- Member of the Editorial Board – Journal of Biological Inorganic Chemistry2009-2012 Member of the Editorial Board – Journal of Biological Inorganic Chemistry2008-2011 Member of the Editorial Board – Journal of Inorganic Biochemistry1996-1999 Assistant to the Editor – Journal of Biological Inorganic Chemistry1994-1995 Assistant to the Editor – La Chimica & l’Industria (SCI)

Reviewing activities/Attività di revisoreReferee for journal in chemistry/chemical biology/Riviste scientifiche:JACS, Chemical Science, Chem Com., BBA, Inorg. Chem, Analytical Chemistry, ACS Biomaterials Science & Engineering, Journal of Chemical Information and modeling, Dalton Transactions, FEBS Letters, J. Biol. Inorg. Chem, Journal of Proteome Research, RSC Advances, npj Parkinson’s Disease, Journal of colloid and interface Science, Materials & Design, Journal of Electroanalytical Chemistry, Sci. Reports, Molecular Oncology, Frontiers in Molecular Biosciences, Metabolomics, ….Referee for national and international funding agencies/agenzie di finanziamento nazionali e internazionali:ERCMIUR/ANVURFundação para a Ciência e a Tecnologia (FCT); Chair of the Chemistry panelSwiss national Science FoundationFrench National Research Agency (ANR)Deutsche Forschungsgemeinschaft (German Research Foundation)Dutch Research Council (NWO)National Institute for Health Research (NIHR) and UK Research and Innovation (UKRI)

Israel Science Foundation (ISF)

Member of selection or evaluation commitees at international institutions/Partecipazione a comitati di selezione o commissioni presso istituzioni straniere

Universidad del Pais Vasco, PhD Thesis defense committee

Ecole Normale Superior Lyon, PhD Thesis defense committee

Universidad de Sevilla, PhD Thesis defense committee

IRB Barcelona, Panel member for a position as Group Leader in Chemical Biology.

Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Member of the classification Jury for Job/Fellowships in "Biochemistry, Spectroscopy, and Molecular Biology" CIENCIA 2008 CQFB 05.

Teaching (University of Florence)/Insegnamenti (Università di Firenze)

Bachelor and Master’s degree/Corsi di Studio

Insegnamento B015921 - INTERAZIONI BIOMOLECOLARI: METODI IN SILICO ED IN VITRO

Modulo B015922 - INTERATTOMICA: STRUTTURA, TERMODINAMICA E CINETICA

Insegnamento B016769 - CHIMICA GENERALE E INORGANICA

Insegnamento B020968 - METABOLOMICA E PROTEOMICA STRUTTURALE NEL DRUG DISCOVERY

Insegnamento B012841 - STRUTTURA ELETTRONICA E PROPRIETA' MOLECOLARI

LT Biotecnologie

Insegnamento: A000938 - CHIMICA GENERALE E INORGANICA

Insegnamento: 0105787 CICLI BIOGEOCHIMICI

LS Biotecnologie Industriali e Ambientali

Insegnamento: 0105907 - LABORATORIO DI TECNOLOGIE STRUMENTALI A (modulo A)

Insegnamento: 0106110 - LABORATORIO DI TECNOLOGIE CHIMICHE A (modulo A)

Insegnamento: 0106073 - METODI DI INDAGINE DI MOLECOLE BIOLOGICHE

Modulo 0106073 - METODI DI INDAGINE DI MOLECOLE BIOLOGICHE (Parte B)

Insegnamento 0105910 - METODI DI INDAGINE STRUTTURALE (Parte B)

Insegnamento: Chimica Generale e Inorganica + Laboratorio di Chimica I

Insegnamento Modelli di Sistemi Biologici

LT Biotecnologie

Insegnamento: Chimica Generale e Inorganica con Laboratorio

CdL Chimica

Insegnamento: Chimica Inorganica II

International Doctorate in Structural Biology/Mechanistic and Structural Systems Biology:

2016 - NMR of large molecular assemblies

2013 - NMR of large molecular assemblies

2012 - Biophysical methods to study biomolecular interactions

2010 - NMR of large molecular assemblies

Other teaching activities/Altre attività didattiche

2013-2014 Docente - Percorso Abilitante Speciale (PAS) – Classe di concorso A013

2011-2012 Docente - Tirocinio Formativo Attivo per Insegnanti (TFA) – Classe di concorso A013

2014-2015 Docente - Tirocinio Formativo Attivo per Insegnanti (TFA) – Classe di concorso A013

2020: Fondamenti di chimica generale (3° edizione italiana; McGraw-Hill Education), Autori Raymond Chang & Kenneth Goldsby; Curatori: Alberto Costanzo, Roberta Galeazzi, Paola Turano.

Technology transfer/Trasferimento tecnologicoSpin-off activities:- Co-founder of the Research Biobank da Vinci European biobank (https://www.unifi.it/vp-11370-da-vinci-european-biobank.html) associated to BBMRI-ERIC via the Italian node BBMRI.itInternational standard development:- Member of the CEN/TC 140/WG 3 Working group "Quality management in the medical laboratory"- Member of the ISO/TC212/WG4 Working group “Clinical laboratory testing and in vitro diagnostic test systems” Public engagement/DivulgazionePublications/PubblicazioniCo-author of the book: L’Ateneo e il mondo della scienza. Firenze e l’Università: Passato, presente e futuro, Firenze University Press, 2024.P. Turano “L'importanza del biobanking nella ricerca”, contributo sulla testata Scenari Sole 24 Ore, Biotecnologie-Innovazione e ricerca tecnologiche, 27 maggio 2019.Bertini I, Turano P, Mangan S, La struttura delle proteine: dal cristallo alla soluzione. Le Scienze, 1998Vari contributi su La Chimica e l’Industria e Il Giorno (1994-1995). Events open to the public/Incontri aperti al pubblicoP. Turano “Via col ferro! "Nano" trasporto e vita “ Lezione aperta alla cittadinanza - Incontri con la città.Leggere il presente per comprendere il futuro. nell' Aula Magna del Rettorato - 14 dicembre 2014: (https://www.youtube.com/watch?v=Cz4v0RMBFk4)P. Turano (& C. Luchinat) “Diagnosi precoce e la ‘rivoluzione’ metabolomica” BRIGHT La notte dei ricercatori in Toscana, settembre 2016.P. Turano “Don’t alter the individual metabolome!” Open Workshop Scientific Background of a European Standardization Activity and Implications for Molecular Diagnostics and Biomarker Development, Medical University of Graz, ottobre 2012. P. Turano “Biobanca: una realtà di ricerca regionale, italiana ed europea al servizio dell’industria biomedica” Convegno FiorGen: opportunità per Firenze, eccellenza per l’Europa. Audotirium Ente Cassa di Risparmio di Firenze, Firenze, 15 giugno 2012. Interviste rilasciate a TG3 Leonardo (2004), TGR Toscana e Controradio (2022), Panorama (2023) Promoting science education/Promozione educazione scientificaP. Turano “La biologia strutturale nell'era dell'AI” in occasione dell’evento di Ateneo “UniStem Day L'infinito viaggio della ricerca scientifica”, 22 Marzo 2024.P. Turano “Prima lezione di ... Scienze Matematiche, Fisiche e Naturrali” in occasione dell’evento di ateneo “Un giorno all’Università”, 1 aprile 2017.P. Turano & S. Menichetti, AIRC nelle Scuole, Scuola secondaria I grado Convenevole da Prato (Prato), 13 aprile 2014.Partecipazione ad attività promosse dalla LM in Biotecnologie Moelcolari e dalla biobanca daVEB in occasione della European Biotech Week (2018-2022).Partecipazione a varie altre attività di orientamento in ingresso promosse dall’ateneo.

Mentoring/Supervisione

PhD Supervisor:

Giorgio Di Paco ”Computational and experimental startegies for the optimization of metal-based drugs in cancer therapy” (Doctorate in Structural Biology 2024-...)

Lucrezia Cosottini “Ferritin-based anticancers” (Doctorate in Chemical Sciences; 2021-2024)

Silvia Ciambellotti “Human ferritin nanocages: from iron oxidation to drug delivery” (International Doctorate in Structural Biology; 2013-2016)

Camilla Rosa “Labeling strategies for metalloprotein structural and functional characterization” (International Doctorate in Mechanistic and Structural Systems Biology; 2009-2012)

Daniela Lalli “Structure and dynamics of complexes and molecular aggregates trough NMR: from protein-ligand interactions to nanobioreactors” (Doctorate in Chemical Sciences; 2007-2010)

Elisa Libralesso “hSOD fALS mutants: an insight into molecular mechanisms of aggregation” (International Doctorate in Structural Biology; 2002-2005)

Visiting PhD students:

Ana Isabel Tristan - University of Almeria (hosted at CERM 15/01/2024-19/04/2024)

Deborah Quaglio - Università di Roma La Sapienza (hosted at CERM 11/01/2016-30/09/2016)

Galit Kuznets - Technion, Haifa (hosted at CERM 07/01/2014-08/02/2014)

J Blas Moreno-Beltrán - University of Seville (hosted at CERM 17/11/2012-28/02/2013)

Post-doc supervisor:

Veronica Ghini (04/2021-present)

Gaia Meoni (07/2021-12/2021), presently: young researcher (RTDa PON) @ Univ. of Florence

Silvia Ciambellotti (02/2017-01/2020), young researcher (RTDa PON) @ Univ. of Florence (31/12/2021-30/06/2023)

Caterina Bernacchioni (10/2014-09/2015 & 02/2013-01/2014), presently: associate professor @ Univ. of Florence

Daniela Lalli (02/2011-01/2014), presently: associate professor @ Univ. Piemonte Orientale

Michael Assfalg (2002), presently: associate professor @ Univ. of Verona

Author identifiers:

Scopus: 7003433915

WOS: F-9089-2011

ORCID: 0000-0002-7683-8614

Paola TURANO

Interessi

Principali linee di ricerca:

ottimizzazione degli esperimenti NMR su sistemi paramagnetici

relazione-struttura funzione in metalloproteine

biologia strutturale

NMR di sistemi parzialmente foldati o unfoldati

NMR di sistemi ad alto peso molecolare

interazioni proteina-leganti via NMR

metabolomica via NMR

biobanche

Paola TURANO

Pubblicazioni

Legenda

Contributo su rivista |

Articolo su libro |

Libro |

Contributo in atti di convegno (proceeding) |

Brevetto |

Curatela | Altro

Altro |

Tesi di Dottorato

Ghini V.; Tristan A.I.; Di Paco G.; Massai L.; Mannelli M.; Gamberi T.; Fernandez I.; Rosato A.; Turano P.; Messori L. (2025). Novel NMR-Based Approach to Reveal the ‘Metabolic Fingerprint’ of Cytotoxic Gold Drugs in Cancer Cells. JOURNAL OF PROTEOME RESEARCH, pp. 0-0, ISSN:1535-3893 DOI

Cosottini, Lucrezia; Buzzigoli, Jacopo; Turano, Paola (2024). Cage Architecture and Reactivity are Preserved in Cysteine‐mutated Ferritin. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, vol. 27, pp. 0-0, ISSN:1434-1948 DOI

Droescher, luigi Dei, Daniele Dominici, Massimo Mazzoni, Marco Benvenuti, Paola Bruni, Paola Turano, Giuseppe Anichini, Samuele Antonini, Luigi Barletti, Luigi Brugnano, Lorenzo Fusi, Veronica Gavagna, Carla Rampichini, Antonella Salvini, Pierandrea Lo Nostro (2024). L’Ateneo e il mondo della scienza.. In: Fulvio Conti, Emanuela Ferretti, Donatella Lippi, Antonella Salvini, Bernardo Sordi, Andrea Zorzi. Firenze e l’Università: Passato, presente e futuro., pp. 323-338, Firenze: Firenze University Press., vol. Firenze e l’Università: Passato, presente e futuro.: DOI Accesso ONLINE all'editore

Cosottini, Lucrezia; Geri, Andrea; Ghini, Veronica; Mannelli, Michele; Zineddu, Stefano; Di Paco, Giorgio; Giachetti, Andrea; Massai, Lara; Severi, Mirko; Gamberi, Tania; Rosato, Antonio; Turano, Paola; Messori, Luigi (2024). Unlocking the Power of Human Ferritin: Enhanced Drug Delivery of Aurothiomalate in A2780 Ovarian Cancer Cells. ANGEWANDTE CHEMIE, vol. 63, pp. 0-0, ISSN:1521-3773 DOI

Ghini, Veronica; Meoni, Gaia; Vignoli, Alessia; Di Cesare, Francesca; Tenori, Leonardo; Turano, Paola; Luchinat, Claudio (2023). Fingerprinting and profiling in metabolomics of biosamples. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, vol. 138-139, pp. 105-135, ISSN:0079-6565 DOI

Riccardi, Christopher; Calvanese, Marzia; Ghini, Veronica; Alonso-Vásquez, Tania; Perrin, Elena; Turano, Paola; Giurato, Giorgio; Weisz, Alessandro; Parrilli, Ermenegilda; Tutino, Maria Luisa; Fondi, Marco (2023). Metabolic Robustness to Growth Temperature of a Cold- Adapted Marine Bacterium. MSYSTEMS, vol. 8, pp. 0-0, ISSN:2379-5077 DOI

Vignoli, Alessia; Meoni, Gaia; Ghini, Veronica; Di Cesare, Francesca; Tenori, Leonardo; Luchinat, Claudio; Turano, Paola (2023). NMR-Based Metabolomics to Evaluate Individual Response to Treatments. In: Alessia Vignoli, Gaia Meoni, Veronica Ghini, Francesca Di Cesare, Leonardo Tenori, Claudio Luchinat, Paola Turano. Handbook of Experimental Pharmacology, pp. 0-0 Springer. DOI

Ghini, Veronica; Vieri, Walter; Celli, Tommaso; Pecchioli, Valentina; Boccia, Nunzia; Alonso-Vásquez, Tania; Pelagatti, Lorenzo; Fondi, Marco; Luchinat, Claudio; Bertini, Laura; Vannucchi, Vieri; Landini, Giancarlo; Turano, Paola (2023). COVID-19: A complex disease with a unique metabolic signature. PLOS PATHOGENS, vol. 19, pp. 0-0, ISSN:1553-7374 DOI

Cosottini, Lucrezia; Zineddu, Stefano; Massai, Lara; Ghini, Veronica; Turano, Paola (2023). 19F: A small probe for a giant protein. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 244, pp. 0-0, ISSN:0162-0134 DOI

Ghini, Veronica; Mannelli, Michele; Massai, Lara; Geri, Andrea; Zineddu, Stefano; Gamberi, Tania; Messori, Luigi; Turano, Paola (2023). The effects of two cytotoxic gold(i) carbene compounds on the metabolism of A2780 ovarian cancer cells: mechanistic inferences through NMR analysis. RSC ADVANCES, vol. 13, pp. 21629-21632, ISSN:2046-2069 DOI

Cosottini, L; Massai, L; Ghini, V; Zineddu, S; Geri, A; Mannelli, M; Ciambellotti, S; Severi, M; Gamberi, T; Messori, L; Turano, P (2023). Bioconjugation of the gold drug auranofin to human ferritin yields a potent cytotoxin. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, vol. 87, pp. 0-0, ISSN:1773-2247 DOI

Caterina Bernacchioni , Roberta Squecco , Tania Gamberi , Veronica Ghini , Fabian Schumacher , Michele Mannelli , Rachele Garella , Eglantina Idrizaj , Francesca Cencetti , Elisa Puliti , Paola Bruni , Paola Turano , Tania Fiaschi and Chiara Donati (2022). S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes. CELLS, vol. 11, pp. 0-0, ISSN:2073-4409 DOI

Ghini V.; Meoni G.; Pelagatti L.; Celli T.; Veneziani F.; Petrucci F.; Vannucchi V.; Bertini L.; Luchinat C.; Landini G.; Turano P. (2022). Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients. PLOS PATHOGENS, vol. 18, pp. 0-0, ISSN:1553-7374 DOI

Ghini V.; Abuja P.M.; Polasek O.; Kozera L.; Laiho P.; Anton G.; Zins M.; Klovins J.; Metspalu A.; Wichmann H.-E.; Gieger C.; Luchinat C.; Zatloukal K.; Turano P. (2022). Impact of the pre-examination phase on multicenter metabolomic studies. NEW BIOTECHNOLOGY, vol. 68, pp. 37-47, ISSN:1871-6784 DOI

Vignoli A.; Tenori L.; Morsiani C.; Turano P.; Capri M.; Luchinat C. (2022). Serum or Plasma (and Which Plasma), That Is the Question. JOURNAL OF PROTEOME RESEARCH, vol. 21, pp. 1061-1072, ISSN:1535-3893 DOI

Silvia Ciambellotti, Luca Conti, Barbara Valtancoli, Claudia Giorgi, Paola Turano (2022). Ferritin carriers to deliver Ru(II)-photosensitizers into cancer cells for photodynamic therapy. In: XLVIII Congresso Nazionale di Chimica Inorganica (INORG 2022), Pisa, 6-9 settembre 2022, Società Chimica Italiana, pp. 1-152. Accesso ONLINE all'editore

luca conti, Gina Elena Giacomazzo, Silvia Ciambellotti, Lucrezia Cosottini, Francesca Cencetti, Paolo Paoli, Alessio Mengoni, Camilla Fagorzi, Paola Turano, Barbara Valtancoli, Claudia Giorgi (2022). Ruthenium(II) polypyridyl complexes as versatile tools in the design of photoresponsive compounds for biological applications. In: 44th International Conference on Coordination Chemistry, AIM Group International, pp. 1-1.

Ghini V.; Maggi L.; Mazzoni A.; Spinicci M.; Zammarchi L.; Bartoloni A.; Annunziato F.; Turano P. (2022). Serum NMR Profiling Reveals Differential Alterations in the Lipoproteome Induced by Pfizer-BioNTech Vaccine in COVID-19 Recovered Subjects and Naïve Subjects. FRONTIERS IN MOLECULAR BIOSCIENCES, vol. 9, pp. 0-0, ISSN:2296-889X DOI

Ghini, Veronica; Magherini, Francesca; Massai, Lara; Messori, Luigi; Turano, Paola (2022). Comparative NMR metabolomics of the responses of A2780 human ovarian cancer cells to clinically established Pt-based drugs. DALTON TRANSACTIONS, vol. 51, pp. 12512-12523, ISSN:1477-9234 DOI

Veronica Ghini, Lorenzo Pelagatti, Tommaso Celli, Francesca Veneziani, Fabrizia Petrucci, Vieri Vannucchi, Laura Bertini, Claudio Luchinat, Giancarlo Landini, Paola Turano (2022). Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients. In: Metabolomics 2022, Valencia, Spain, 19-23 June 2022, Metabolomic Society, pp. 1-310. Accesso ONLINE all'editore

Meoni, G; Tenori, L; Schade, S; Licari, C; Pirazzini, C; Bacalini, MG; Garagnani, P; Turano, P; Trenkwalder, C; Franceschi, C; Mollenhauer, B; Luchinat, C (2022). Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson's disease patients. NPJ PARKINSON'S DISEASE, vol. 8, pp. 1-10, ISSN:2373-8057 DOI Accesso ONLINE all'editore

Luca Conti, Silvia Ciambellotti, Gina Elena Giacomazzo, Veronica Ghini, Lucrezia Cosottini, Elisa Puliti, Mirko Severi, Emiliano Fratini, Francesca Cencetti, Paola Bruni, Barbara Valtancoli, Claudia Giorgi, Paola Turano (2022). Ferritin nanocomposites for the selective delivery of photosensitizing ruthenium-polypyridyl compounds to cancer cells. INORGANIC CHEMISTRY FRONTIERS, pp. 1-12, ISSN:2052-1553 DOI Accesso ONLINE all'editore

Meoni, Gaia; Ghini, Veronica; Maggi, Laura; Vignoli, Alessia; Mazzoni, Alessio; Salvati, Lorenzo; Capone, Manuela; Vanni, Anna; Tenori, Leonardo; Fontanari, Paolo; Lavorini, Federico; Peris, Adriano; Bartoloni, Alessandro; Liotta, Francesco; Cosmi, Lorenzo; Luchinat, Claudio; Annunziato, Francesco; Turano, Paola (2021). Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab. PLOS PATHOGENS, vol. 17, pp. e1009243-e1009243, ISSN:1553-7374 DOI

Massai L.; Ciambellotti S.; Cosottini L.; Messori L.; Turano P.; Pratesi A. (2021). Direct detection of iron clusters in L ferritins through ESI-MS experiments. DALTON TRANSACTIONS, vol. 50, pp. 16464-16467, ISSN:1477-9226 DOI

Tsopra R.; Fernandez X.; Luchinat C.; Alberghina L.; Lehrach H.; Vanoni M.; Dreher F.; Sezerman O.U.; Cuggia M.; de Tayrac M.; Miklasevics E.; Itu L.M.; Geanta M.; Ogilvie L.; Godey F.; Boldisor C.N.; Campillo-Gimenez B.; Cioroboiu C.; Ciusdel C.F.; Coman S.; Hijano Cubelos O.; Itu A.; Lange B.; Le Gallo M.; Lespagnol A.; Mauri G.; Soykam H.O.; Rance B.; Turano P.; Tenori L.; Vignoli A.; Wierling C.; Benhabiles N.; Burgun A. (2021). A framework for validating AI in precision medicine: considerations from the European ITFoC consortium. BMC MEDICAL INFORMATICS AND DECISION MAKING, vol. 21, pp. 274-274, ISSN:1472-6947 DOI

Pirazzini C.; Azevedo T.; Baldelli L.; Bartoletti-Stella A.; Calandra-Buonaura G.; Dal Molin A.; Dimitri G.M.; Doykov I.; Gomez-Garre P.; Hagg S.; Hallqvist J.; Halsband C.; Heywood W.; Jesus S.; Jylhava J.; Kwiatkowska K.M.; Labrador-Espinosa M.A.; Licari C.; Maturo M.G.; Mengozzi G.; Meoni G.; Milazzo M.; Perinan-Tocino M.T.; Ravaioli F.; Sala C.; Sambati L.; Schade S.; Schreglmann S.; Spasov S.; Tenori L.; Williams D.; Xumerle L.; Zago E.; Bhatia K.P.; Capellari S.; Cortelli P.; Garagnani P.; Houlden H.; Lio P.; Luchinat C.; Delledonne M.; Mills K.; Mir P.; Mollenhauer B.; Nardini C.; Pedersen N.L.; Provini F.; Strom S.; Trenkwalder C.; Turano P.; Bacalini M.G.; Franceschi C.; Adarmes-Gomez A.; Bonilla-Toribio M.; Boninsegna C.; Broli M.; Buiza-Rueda D.; Carrion-Claro M.; Cilea R.; Clayton R.; Molin A.D.; De Luca S.; De Massis P.; Escuela-Martin R.; Fabbri G.; Gabellini A.; Giuliani C.; Guaraldi P.; Huertas I.; Macias D.; Macri S.; Magrinelli F.; Rodriguez J.F.M.; Mignani F.; Nassetti S.A.; Scaglione C.L.M.; Tejera-Parrado C.; Valzania F.; Ortega R.V. (2021). A geroscience approach for Parkinson's disease: Conceptual framework and design of PROPAG-AGEING project. MECHANISMS OF AGEING AND DEVELOPMENT, vol. 194, pp. 0-0, ISSN:0047-6374 DOI

Ciambellotti S.; Pratesi A.; Tassone G.; Turano P.; Mangani S.; Pozzi C. (2021). Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin. CHEMISTRY-A EUROPEAN JOURNAL, vol. -, pp. 0-0, ISSN:0947-6539 DOI

Ghini V.; Senzacqua T.; Massai L.; Gamberi T.; Messori L.; Turano P. (2021). NMR reveals the metabolic changes induced by auranofin in A2780 cancer cells: Evidence for glutathione dysregulation. DALTON TRANSACTIONS, vol. 50, pp. 6349-6355, ISSN:1477-9226 DOI

Fondi M.; Gonzi S.; Dziurzynski M.; Turano P.; Ghini V.; Calvanese M.; Colarusso A.; Lauro C.; Parrilli E.; Tutino M.L. (2021). Modelling hCDKL5 heterologous expression in bacteria. METABOLITES, vol. 11, pp. 0-0, ISSN:2218-1989 DOI

Ghini V.; Abuja P.M.; Polasek O.; Kozera L.; Laiho P.; Anton G.; Zins M.; Klovins J.; Metspalu A.; Wichmann H.-E.; Gieger C.; Luchinat C.; Zatloukal K.; Turano P. (2021). Metabolomic Fingerprints in Large Population Cohorts: Impact of Preanalytical Heterogeneity. CLINICAL CHEMISTRY, vol. 67, pp. 1153-1155, ISSN:1530-8561 DOI

Bendinelli B.; Vignoli A.; Palli D.; Assedi M.; Ambrogetti D.; Luchinat C.; Caini S.; Saieva C.; Turano P.; Masala G. (2021). Prediagnostic circulating metabolites in female breast cancer cases with low and high mammographic breast density. SCIENTIFIC REPORTS, vol. 11, pp. 13025-13025, ISSN:2045-2322 DOI

Perrin E.; Ghini V.; Giovannini M.; Di Patti F.; Cardazzo B.; Carraro L.; Fagorzi C.; Turano P.; Fani R.; Fondi M. (2020). Diauxie and co-utilization of carbon sources can coexist during bacterial growth in nutritionally complex environments. NATURE COMMUNICATIONS, vol. 11, pp. 3135-3151, ISSN:2041-1723 DOI

Lucia Banci, Letizia Barbieri, Vito Calderone, Francesca Cantini, Linda Cerofolini, Simone Ciofi-Baffoni, Isabella C. Felli, Marco Fragai, Moreno Lelli, Claudio Luchinat, Enrico Luchinat, Giacomo Parigi, Mario Piccioli, Roberta Pierattelli, Enrico Ravera, Antonio Rosato, Leonardo Tenori, Paola Turano (2020). Biomolecular NMR at 1.2 GHz. DOI Accesso ONLINE all'editore

Lalli D.; Rosa C.; Allegrozzi M.; Turano P. (2020). Distal unfolding of ferricytochrome C induced by the F82K mutation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 0-0, ISSN:1661-6596 DOI

Vignoli A.; Muraro E.; Miolo G.; Tenori L.; Turano P.; Di Gregorio E.; Steffan A.; Luchinat C.; Corona G. (2020). Effect of estrogen receptor status on circulatory immune and metabolomics profiles of her2-positive breast cancer patients enrolled for neoadjuvant targeted chemotherapy. CANCERS, vol. 12, pp. 0-0, ISSN:2072-6694 DOI

Vignoli A.; Paciotti S.; Tenori L.; Eusebi P.; Biscetti L.; Chiasserini D.; Scheltens P.; Turano P.; Teunissen C.; Luchinat C.; Parnetti L. (2020). Fingerprinting Alzheimer's Disease by 1H Nuclear Magnetic Resonance Spectroscopy of Cerebrospinal Fluid. JOURNAL OF PROTEOME RESEARCH, vol. 19, pp. 1696-1705, ISSN:1535-3907 DOI

Antonaros F.; Ghini V.; Pulina F.; Ramacieri G.; Cicchini E.; Mannini E.; Martelli A.; Feliciello A.; Lanfranchi S.; Onnivello S.; Vianello R.; Locatelli C.; Cocchi G.; Pelleri M.C.; Vitale L.; Strippoli P.; Luchinat C.; Turano P.; Piovesan A.; Caracausi M. (2020). Plasma metabolome and cognitive skills in Down syndrome. SCIENTIFIC REPORTS, vol. 10, pp. 0-0, ISSN:2045-2322 DOI

Ciambellotti S.; Pozzi C.; Mangani S.; Turano P. (2020). Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin. CHEMISTRY-A EUROPEAN JOURNAL, pp. 0-0, ISSN:0947-6539 DOI

Tenori L.; Turano P.; Luchinat C. (2020). Metabolic profiling by nm. EMAGRES, vol. 9, pp. 199-204, ISSN:2055-6101 DOI

Ciambellotti, Silvia; Turano, Paola (2019). Structural Biology of Iron-Binding Proteins by NMR Spectroscopy. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, vol. 2019, pp. 569-576, ISSN:1434-1948 DOI Accesso ONLINE all'editore

Pozzi, Cecilia; Di Pisa, Flavio; Lalli, Daniela; Rosa, Camilla; Turano, Paola; Mangani, Stefano (2019). Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H′ ferritin. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 197, pp. 0-0, ISSN:0162-0134 DOI Accesso ONLINE all'editore

Vignoli, Alessia; Ghini, Veronica; Meoni, Gaia; Licari, Cristina; Takis, Panteleimon G; Tenori, Leonardo; Turano, Paola; Luchinat, Claudio (2019). High-throughput metabolomics by 1D NMR. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 58, pp. 968-994, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Ghini, Veronica; Quaglio, Deborah; Luchinat, Claudio; Turano, Paola (2019). NMR for sample quality assessment in metabolomics. NEW BIOTECHNOLOGY, vol. 52, pp. 25-34, ISSN:1871-6784 DOI Accesso ONLINE all'editore

Ghini, Veronica; Chevance, Soizic; Turano, Paola (2019). About the use of 13C-13C NOESY in bioinorganic chemistry. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 192, pp. 25-32, ISSN:0162-0134 DOI Accesso ONLINE all'editore

Takis, Panteleimon G.; Ghini, Veronica; Tenori, Leonardo; Turano, Paola; Luchinat, Claudio (2019). Uniqueness of the NMR approach to metabolomics. TRAC. TRENDS IN ANALYTICAL CHEMISTRY, vol. 120, pp. 0-0, ISSN:0165-9936 DOI Accesso ONLINE all'editore

D'Alessandro G.; Quaglio D.; Monaco L.; Lauro C.; Ghirga F.; Ingallina C.; De Martino M.; Fucile S.; Porzia A.; Di Castro M.A.; Bellato F.; Mastrotto F.; Mori M.; Infante P.; Turano P.; Salmaso S.; Caliceti P.; Di Marcotullio L.; Botta B.; Ghini V.; Limatola C. (2019). 1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma. CELL COMMUNICATION AND SIGNALING, vol. 17, pp. 108-120, ISSN:1478-811X DOI Accesso ONLINE all'editore

Dagher G.; Becker K.-F.; Bonin S.; Foy C.; Gelmini S.; Kubista M.; Kungl P.; Oelmueller U.; Parkes H.; Pinzani P.; Riegman P.; Schroder U.; Stumptner C.; Turano P.; Sjoback R.; Wutte A.; Zatloukal K. (2019). Pre-analytical processes in medical diagnostics: New regulatory requirements and standards. NEW BIOTECHNOLOGY, vol. 52, pp. 121-125, ISSN:1871-6784 DOI Accesso ONLINE all'editore

Checcucci, Alice; diCenzo, George; Ghini, Veronica; Bazzicalupo, Marco; Becker, Anke; Decorosi, Francesca; Döhlemann, Johannes; Fagorzi, Camilla; Finan, Turlough M; Fondi, Marco; Luchinat, Claudio; Turano, Paola; Vignolini, Tiziano; Viti, Carlo; Mengoni, Alessio (2018). Creation and Characterization of a Genomically Hybrid Strain in the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti. ACS SYNTHETIC BIOLOGY, vol. 7, pp. 2365-2378, ISSN:2161-5063 DOI Accesso ONLINE all'editore

Caracausi, Maria; Ghini, Veronica; Locatelli, Chiara; Mericio, Martina; Piovesan, Allison; Antonaros, Francesca; Pelleri, Maria Chiara; Vitale, Lorenza; Vacca, Rosa Anna; Bedetti, Federica; Mimmi, Maria Chiara; Luchinat, Claudio; Turano, Paola; Strippoli, Pierluigi; Cocchi, Guido (2018). Plasma and urinary metabolomic profiles of Down syndrome correlate with alteration of mitochondrial metabolism. SCIENTIFIC REPORTS, vol. 8, pp. 0-0, ISSN:2045-2322 DOI Accesso ONLINE all'editore

Cutrin, Juan Carlos; Alberti, Diego; Bernacchioni, Caterina; Ciambellotti, Silvia; Turano, Paola; Luchinat, Claudio; Crich, Simonetta Geninatti*; Aime, Silvio (2018). Cancer cell death induced by ferritins and the peculiar role of their labile iron pool. ONCOTARGET, vol. 9, pp. 27974-27984, ISSN:1949-2553 DOI Accesso ONLINE all'editore

Doucet, Marika; Becker, Karl Friedrich; Björkman, Jens; Bonnet, Jacques; Clément, Bruno; Daidone, Maria-Grazia; Duyckaerts, Charles; Erb, Gilles; Haslacher, Helmuth; Hofman, Paul; Huppertz, Berthold; Junot, Christophe; Lundeberg, Joakim; Metspalu, Andres; Lavitrano, Marialuisa; Litton, Jan-Eric; Moore, Helen; Morente, Manuel; Naimi, Ben-Youssef; Oelmueller, Uwe; Ollier, Bill; Parodi, Barbara; Ruan, Liangliang; Stanta, Giorgio; Turano, Paola; Vaught, Jim; Watson, Peter; Wichmann, H-Erich; Yuille, Martin; Zaomi, Myriam; Zatloukal, Kurt; Dagher, Georges (2017). Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking. BIOPRESERVATION AND BIOBANKING, vol. 23, pp. 9879-9887, ISSN:1947-5535 DOI Accesso ONLINE all'editore

Bernacchioni, Caterina; Ghini, Veronica; Cencetti, Francesca; Japtok, Lukasz; Donati, Chiara; Bruni, Paola; Turano, Paola (2017). NMR metabolomics highlights sphingosine kinase-1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells. MOLECULAR ONCOLOGY, vol. 11, pp. 517-533-533, ISSN:1574-7891 DOI

Pozzi, Cecilia; Ciambellotti, Silvia; Bernacchioni, Caterina; Di Pisa, Flavio; Mangani, Stefano; Turano, Paola (2017). Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ3-oxo)Tris[(μ2-peroxo)] triiron(III) cluster. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 114, pp. 2580-2585, ISSN:0027-8424 DOI Accesso ONLINE all'editore

Zanzoni, Serena; Pagano, Katiuscia; D'Onofrio, Mariapina; Assfalg, Michael; Ciambellotti, Silvia; Bernacchioni, Caterina; Turano, Paola; Aime, Silvio; Ragona, Laura; Molinari, Henriette (2017). Unsaturated Long-Chain Fatty Acids Are Preferred Ferritin Ligands That Enhance Iron Biomineralization. CHEMISTRY-A EUROPEAN JOURNAL, vol. 23, pp. 9879-9887, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Sala, Davide; Ciambellotti, Silvia; Giachetti, Andrea; Turano, Paola; Rosato, Antonio (2017). Investigation of the Iron(II) Release Mechanism of Human H-Ferritin as a Function of pH. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 57, pp. 2112-2118, ISSN:1549-9596 DOI

Bernacchioni, Caterina; Turano, Paola; Donati, Chiara (2017). Targeting sphingosine kinase 1 localization as novel target for ovarian cancer therapy. TRANSLATIONAL CANCER RESEARCH, vol. 6, pp. S1277-S1280, ISSN:2218-676X DOI Accesso ONLINE all'editore

Moreno-Beltrán, Blas; Guerra-Castellano, Alejandra; Díaz-Quintana, Antonio; Del Conte, Rebecca; García-Mauriño, Sofía M; Díaz-Moreno, Sofía; González-Arzola, Katiuska; Santos-Ocaña, Carlos; Velázquez-Campoy, Adrián; De la Rosa, Miguel A; Turano, Paola; Díaz-Moreno, Irene (2017). Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 114, pp. E3041-E3050-E3050, ISSN:0027-8424 DOI

Chandramouli, Balasubramanian; Bernacchioni, Caterina; Di Maio, Danilo; Turano, Paola; Brancato, Giuseppe (2016). Electrostatic and structural bases of Fe2+ translocation through ferritin channels. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 291, pp. 25617-25628, ISSN:0021-9258 DOI Accesso ONLINE all'editore

Feifel, Sven Christian; Stieger, Kai Ralf; Kapp, Andreas; Weber, Dennis; Allegrozzi, Marco; Piccioli, Mario; Turano, Paola; Lisdat, Fred (2016). Insights into Interprotein Electron Transfer of Human Cytochrome c Variants Arranged in Multilayer Architectures by Means of an Artificial Silica Nanoparticle Matrix. ACS OMEGA, vol. 1, pp. 1058-1066, ISSN:2470-1343 DOI Accesso ONLINE all'editore

Bernacchioni, Caterina; Pozzi, Cecilia; Di Pisa, Flavio; Mangani, Stefano; Turano, Paola (2016). Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity. CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, pp. 16213-16219, ISSN:0947-6539 DOI Accesso ONLINE all'editore

Bernacchioni, C.; Ghini, V.; Theil, E.C.; Turano, P. (2016). Modulating the permeability of ferritin channels. RSC ADVANCES, vol. 6, pp. 21219-21227, ISSN:2046-2069 DOI Accesso ONLINE all'editore

Wallner-Liebmann, Sandra; Tenori, Leonardo; Mazzoleni, Antonio; Dieber-Rotheneder, Martina; Konrad, Manuela; Hofmann, Peter; Luchinat, Claudio; Turano, Paola; Zatloukal, Kurt (2016). Individual human metabolic phenotype analyzed by 1H NMR of saliva samples. JOURNAL OF PROTEOME RESEARCH, vol. 15, pp. 1787-1793, ISSN:1535-3893 DOI Accesso ONLINE all'editore

Ravera, Enrico; Ciambellotti, Silvia; Cerofolini, Linda; Martelli, Tommaso; Kozyreva, Tatiana; Bernacchioni, Caterina; Giuntini, Stefano; Fragai, Marco; Turano, Paola; Luchinat, Claudio (2016). Solid-State NMR of PEGylated Proteins. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 55, pp. 2446-9-2449, ISSN:1433-7851 DOI Accesso ONLINE all'editore

Wruck, Wasco; Kashofer, Karl; Rehman, Samrina; Daskalaki, Andriani; Berg, Daniela; Gralka, Ewa; Jozefczuk, Justyna; Drews, Katharina; Pandey, Vikash; Regenbrecht, Christian; Wierling, Christoph; Turano, Paola; Korf, Ulrike; Zatloukal, Kurt; Lehrach, Hans; Westerhoff, Hans V.; Adjaye, James (2015). Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. SCIENTIFIC DATA, vol. 2, pp. 150068-150068, ISSN:2052-4463 DOI Accesso ONLINE all'editore

Mario Piccioli; Paola Turano (2015). Transient iron coordination sites in proteins: Exploiting the dual nature of paramagnetic NMR. COORDINATION CHEMISTRY REVIEWS, vol. 284, pp. 313-328, ISSN:0010-8545 DOI

Wallner-Liebmann S;Gralka E;Tenori L;Konrad M;Hofmann P;Dieber-Rotheneder M;Turano P;Luchinat C;Zatloukal K (2015). The impact of free or standardized lifestyle and urine sampling protocol on metabolome recognition accuracy.. GENES & NUTRITION, vol. 10, pp. 441-449, ISSN:1555-8932 DOI

Salek, Reza M.; Neumann, Steffen; Schober, Daniel; Hummel, Jan; Billiau, Kenny; Kopka, Joachim; Correa, Elon; Reijmers, Theo; Rosato, Antonio; Tenori, Leonardo; Turano, Paola; Marin, Silvia; Deborde, Catherine; Jacob, Daniel; Rolin, Dominique; Dartigues, Benjamin; Conesa, Pablo; Haug, Kenneth; Rocca-Serra, Philippe; O’Hagan, Steve; Hao, Jie; van Vliet, Michael; Sysi-Aho, Marko; Ludwig, Christian; Bouwman, Jildau; Cascante, Marta; Ebbels, Timothy; Griffin, Julian L.; Moing, Annick; Nikolski, Macha; Oresic, Matej; Sansone, Susanna-Assunta; Viant, Mark R.; Goodacre, Royston; Günther, Ulrich L.; Hankemeier, Thomas; Luchinat, Claudio; Walther, Dirk; Steinbeck, Christoph (2015). COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access. METABOLOMICS, vol. 11, pp. 1587-1597, ISSN:1573-3882 DOI Accesso ONLINE all'editore

Ghini, Veronica; Unger, Florian T; Tenori, Leonardo; Turano, Paola; Juhl, Hartmut; David, Kerstin A (2015). Metabolomics profiling of pre-and post-anesthesia plasma samples of colorectal patients obtained via Ficoll separation. METABOLOMICS, vol. 11, pp. 1769-1778-1778, ISSN:1573-3882 DOI

Pozzi, Cecilia; Di Pisa, Flavio; Lalli, Daniela; Rosa, Camilla; Theil, Elizabeth; Turano, Paola; Mangani, Stefano (2015). Time-lapse anomalous X-ray diffraction shows how Fe<sup>2+</sup> substrate ions move through ferritin protein nanocages to oxidoreductase sites. ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY, vol. 71, pp. 941-953, ISSN:0907-4449 DOI Accesso ONLINE all'editore

Pozzi, Cecilia; Di Pisa, Flavio; Bernacchioni, Caterina; Ciambellotti, Silvia; Turano, Paola; Mangani, Stefano (2015). Iron binding to human heavy-chain ferritin. ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY, vol. 71, pp. 1909-1920, ISSN:0907-4449 DOI Accesso ONLINE all'editore

Bernacchioni, Caterina; Ciambellotti, Silvia; Theil, Elizabeth C.; Turano, Paola (2015). Is His54 a gating residue for the ferritin ferroxidase site?. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, vol. 1854, pp. 1118-1122, ISSN:1570-9639 DOI Accesso ONLINE all'editore

Carotenuto, Dario; Luchinat, Claudio; Marcon, Giordana; Rosato, Antonio; Turano, Paola (2015). The Da Vinci European BioBank: A Metabolomics-Driven Infrastructure. JOURNAL OF PERSONALIZED MEDICINE, vol. 5, pp. 107-19-119, ISSN:2075-4426 DOI

Elizabeth C. Theil;Paola Turano;Veronica Ghini;Marco Allegrozzi;Caterina Bernacchioni (2014). Coordinating subdomains of ferritin protein cages with catalysis and biomineralization viewed from the C 4 cage axes. JBIC, vol. 19, pp. 615-622, ISSN:0949-8257 DOI

Caterina Bernacchioni;Veronica Ghini;Cecilia Pozzi;Flavio Di Pisa;Elizabeth C. Theil;Paola Turano (2014). Loop Electrostatics Modulates the Intersubunit Interactions in Ferritin. ACS CHEMICAL BIOLOGY, vol. 9, pp. 2517-2525, ISSN:1554-8929 DOI

Abdul-Hamid Emwas;Claudio Luchinat;Paola Turano;Leonardo Tenori;Raja Roy;Reza M. Salek;Danielle Ryan;Jasmeen S. Merzaban;Rima Kaddurah-Daouk;Ana Carolina Zeri;G. A. Nagana Gowda;Daniel Raftery;Yulan Wang;Lorraine Brennan;David S. Wishart (2014). Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review. METABOLOMICS, pp. 872-894, ISSN:1573-3882 DOI

Galit Kuznets;Elena Vigonsky;Ziva Weissman;Daniela Lalli;Tsvia Gildor;Sarah J. Kauffman;Paola Turano;Jeffrey Becker;Oded Lewinson;Daniel Kornitzer (2014). A Relay Network of Extracellular Heme-Binding Proteins Drives C. albicans Iron Acquisition from Hemoglobin. PLOS PATHOGENS, vol. 10, pp. e1004407-e1004407, ISSN:1553-7374 DOI

Paola Turano (2014). Colorectal cancer: the potential of metabolic fingerprinting. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, vol. 8, pp. 847-849, ISSN:1747-4124 DOI

Franziska Wegerich;Andrea Giachetti;Marco Allegrozzi;Fred Lisdat;Paola Turano (2013). Mechanistic insights into the superoxide–cytochrome c reaction by lysine surface scanning. JBIC, vol. 18, pp. 429-440, ISSN:0949-8257 DOI

Stefano Cacciatore;Xiaoyu Hu;Christian Viertler;Marcel Kap;Gerwin A. Bernhardt;Hans-Jörg Mischinger;Peter Riegman;Kurt Zatloukal;Claudio Luchinat;Paola Turano (2013). Effects of Intra- and Post-Operative Ischemia on the Metabolic Profile of Clinical Liver Tissue Specimens Monitored by NMR. JOURNAL OF PROTEOME RESEARCH, vol. 12, pp. 5723-5729, ISSN:1535-3893 DOI

Cacciatore S; Piccioli M; Turano P (2013). Electron self-exchange of cytochrome c measured via 13C detected protonless NMR. JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, vol. 17, pp. 142-149, ISSN:1088-4246 DOI

R. Del Conte; D. Lalli; P. Turano (2013). NMR as a tool to target protein-protein interactions. In: Stefano Mangani. Disruption of Protein-Protein Interfaces. In Search of New Inhibitors, pp. 83-111, Heidelberg: Springer, ISBN:9783642379987. DOI

Cristiana, Castaldo; Silvia, Ciambellotti; Raquel, de Pablo-Latorre; Daniela, Lalli; Valentina, Porcari; Paola, Turano (2013). Soluble Variants of Human Recombinant Glutaminyl Cyclase. PLOS ONE, vol. 8, pp. 1-9, ISSN:1932-6203 DOI

Daniela Lalli;Paola Turano (2013). Solution and Solid State NMR Approaches To Draw Iron Pathways in the Ferritin Nanocage. ACCOUNTS OF CHEMICAL RESEARCH, vol. 46, pp. 2676-2685, ISSN:0001-4842 DOI

Franziska Wegerich;Andrea Giachetti;Marco Allegrozzi;Fred Lisdat;Paola Turano (2013). Cytochrome c and superoxide: a reply. JBIC, pp. 867-869, ISSN:0949-8257 DOI

Rui M. Almeida;Paola Turano;Isabel Moura;José J. G. Moura;Sofia R. Pauleta (2013). Superoxide Reductase: Different Interaction Modes with its Two Redox Partners. CHEMBIOCHEM, vol. 14, pp. 1858-1866, ISSN:1439-4227 DOI

Elizabeth C Theil;Paola Turano (2013). Metalloenzymes: Cage redesign explains assembly. NATURE CHEMICAL BIOLOGY, vol. 9, pp. 143-144, ISSN:1552-4450 DOI

L. Ferella; A. Rosato; P. Turano (2012). Determination of protein structure and dynamics. In: I. Bertini, K.S. McGreevy, G. Parigi. NMR of biomolecules. Towards mechanistic systems biology, pp. 53-94, Weinheim: Wiley-Blackwell, ISBN:9783527328505. DOI

J. Jozefczuk; K. Kashofer; R. Ummanni; F. Henjes; S. Rehman; S. Geenen; W. Wruck; C. Regenbrecht; A. Daskalaki; C. Wierling; P. Turano; I. Bertini; U. Korf; K. Zatloukal; H. V. Westerhoff; H. Lehrach; J. Adjaye (2012). A systems biology approach to deciphering the etiology of steatosis employing patient-derived dermal fibroblasts and iPS cells. FRONTIERS IN PHYSIOLOGY, vol. 3, pp. 1-18, ISSN:1664-042X DOI

B. Zambelli ; N. Cremades; P. Neyroz; P. Turano; V.N. Uversky; S. Ciurli (2012). Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme.. MOLECULAR BIOSYSTEMS, vol. 8, pp. 220-228, ISSN:1742-206X DOI

L. Ferella; A. Rosato; P. Turano (2012). What Can be Learned About the Structure and Dynamics of Biomolecules from NMR. In: I. Bertini, K.S. McGreevy, G. Parigi. NMR of biomolecules. Towards Mechanistic Systems Biology, pp. 33-45, Weinheim: Wiley-Blackwell, ISBN:9783527328505. DOI

I. Bertini;D. Lalli; S. Mangani; C. Pozzi; C. Rosa; E.C. Theil; P. Turano (2012). Structural insights into the ferroxidase site of ferritins from higher eukaryotes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 134, pp. 6169-6176, ISSN:0002-7863 DOI

I.Bertini; F.Engelke; C.Luchinat; G.Parigi; E.Ravera;C.Rosa; P.Turano; (2012). NMR properties of sedimented solutes. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 14, pp. 439-447, ISSN:1463-9076 DOI

I.Bertini; S.Cacciatore; B.V.Jensen; J.V.Schou; J.S.Johansen; M.Kruhøffer; C.Luchinat; D.L.Nielsen; P.Turano; (2012). Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer. CANCER RESEARCH, vol. 72, pp. 356-364, ISSN:0008-5472 DOI

C. Caillet-Saguy; M. Piccioli; P. Turano; G. Lukat-Rodgers; N. Wolff; K.R. Rodgers; N. Izadi-Pruneyre; M. Delepierre; A. Lecroisey (2012). Role of the iron axial ligands of heme carrier HasA in heme uptake and release. JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, pp. 26932-26943, ISSN:1083-351X DOI

I.Bertini; S.Chevance; R.Del Conte; D.Lalli; P.Turano (2011). The Anti-Apoptotic Bcl-xL Protein, a New Piece in the Puzzle of Cytochrome C Interactome. PLOS ONE, vol. 6(4), pp. e18329-e18329, ISSN:1932-6203 DOI

P.Bernini; I.Bertini; C.Luchinat; P.Nincheri; S.Staderini; P.Turano (2011). Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks. JOURNAL OF BIOMOLECULAR NMR, vol. 49 (3-4), pp. 231-243, ISSN:0925-2738 DOI

R. Gattai; P. Turano; P. Bechi (2011). New Approach to Diagnosis and Prognosis. In: A. Barbarisi. Biotechnology in Surgery, pp. 15-40, Berlin Heidelberg: Springer -Verlag, ISBN:9788847016576. DOI

F. Wegerich; P. Turano; M. Allegrozzi; H. Möhwald;F. Lisdat (2011). Electroactive Multilayer Assemblies of Bilirubin Oxidase and Human Cytochrome c Mutants: Insight in Formation and Kinetic Behavior.. LANGMUIR, vol. 27, pp. 4202-4211, ISSN:0743-7463 DOI

I.Bertini; C.Luchinat; G.Parigi; E.Ravera; B.Reif; P.Turano (2011). Solid-state NMR of proteins sedimented by ultracentrifugation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108(26), pp. 10396-10399, ISSN:1091-6490 DOI

P.Turano; D.Lalli; I.C.Felli; E.C.Theil; I.Bertini (2010). NMR reveals a pathway for iron mineral precursors to the central cavity of ferritin. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 107, pp. 545-550, ISSN:1091-6490 DOI

M.Agamennone; L.Cesari; D.Lalli; E.Turlizzi; R. Del Conte; P. Turano; S. Mangani; A. Padova (2010). Fragmenting the S100B–p53 Interaction: CombinedVirtual/Biophysical Screening Approaches to IdentifyLigands. CHEMMEDCHEM, vol. 5, pp. 428-435, ISSN:1860-7179 DOI

R. GAttai; P. Bechi; R. Turano (2010). Secondary Peritoneal Carcinomatosis and BiotecHnology: A New Approach to Diagnosis and Terapy. In: A. Barbarisi. Biotechnology in Surgery, pp. 15-18, milano: Springer, ISBN:9788847016576. DOI

F. Musiani; B. Bertoa; A. Magistrato; B. Zambelli; P. Turano; V. Losasso; C. Micheletti; S. Ciurli; P. Carloni (2010). Computational Study of the DNA-Binding Protein Helicobacter pylori NikR: The Role of Ni2+. JOURNAL OF CHEMICAL THEORY AND COMPUTATION, vol. 6, pp. 3503-3515, ISSN:1549-9618 DOI

Turano P. (2010). Heme acquisition by hemophores: a lesson from NMR. In: K.M. Kadish, K.M. Smith, R. Guillard. Handbook of Porphyrin Science, pp. 339-365, Singapore: World Scientific (Singapore, New Jersey, London, Hong Kong), ISBN:9789814307192.

F. Wegerich; P. Turano; M. Allegrozzi; H. Moehwald; F. Lisdat (2009). Superoxide biosensing with engineered cytochrome c. PROCEDIA CHEMISTRY, vol. 1, pp. 1287-1290, ISSN:1876-6196 DOI Accesso ONLINE all'editore

F. Wegerich; P. Turano; M. Allegrozzi; H. Moehwald; F. Lisdat (2009). Cytochrome c mutants for superoxide biosensors. ANALYTICAL CHEMISTRY, vol. 15, pp. 2976-2984, ISSN:1520-6882 DOI

B.Zambelli; P.Turano;F.Musiani;P.Neyroz;S.Ciurli (2009). Zn2+-linked dimerization of UreG from Helicobacter pylori, a chaperone involved in nickel trafficking and urease activation. PROTEINS, vol. 74, pp. 222-239, ISSN:0887-3585 DOI

M.Bellucci;B.Zambelli;F.Musiani;P.Turano;S.Ciurli (2009). Helicobacter pylori UreE, a urease accessory protein: specific Ni(2+)- and Zn(2+)-binding properties and interaction with its cognate UreG. BIOCHEMICAL JOURNAL, vol. 422, pp. 91-100, ISSN:1470-8728 DOI

C. Caillet-Saguy; M. Piccioli; P. Turano; N. Izadi-Prunyere; M. Delepierre; I. Bertini; A. Lecroisey (2009). Mapping the interaction between the Hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 131, pp. 1736-1744, ISSN:0002-7863 DOI

I. Bertini; P. Turano (2008). Inorganic chemistry in biology. In: T.P. Begley. Wiley Encyclopedia of Chemical Biology, pp. 1-9, Singapore: Wiley-Blackwell, ISBN:9780471754770. DOI

C. CAILLET-SAGUY; P. TURANO; M. PICCIOLI; G.S. LUKAT-RODGERS; M. CZJZEK; B. GUIGLIARELLI; N. IZADI-PRUNEYRE; K.R. RODGERS; M. DELEPIERRE; A. LECROISEY (2008). Deciphering the structural role of Histidine 83 for Heme binding in Hemophore HasA. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, pp. 5960-5970, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824: DOI

M.Assfalg; I.Bertini; R.Del Conte; A.Giachetti; P.Turano (2007). Cytochrome c and organic molecules: solution structure of the p-aminophenol adduct. BIOCHEMISTRY, vol. 46, pp. 6232-6238, ISSN:0006-2960 DOI

W.Bermel; I.Bertini; I.C.Felli; M.Matzapetakis; R.Pierattelli; E.C.Theil; P.Turano (2007). A method for C(alpha) direct-detection in protonless NMR. JOURNAL OF MAGNETIC RESONANCE, vol. 188, pp. 301-310, ISSN:1090-7807 DOI

L.Banci; I.Bertini; N.D'Amelio; E.Libralesso; P.Turano; J.S.Valentine (2007). Metalation of the amyotrophic lateral sclerosis mutant glycine 37 to arginine superoxide dismutase (SOD1) apoprotein restores its structural and dynamical properties in solution to those of metalated wild-type SOD1.. BIOCHEMISTRY, vol. 46, pp. 9953-9962, ISSN:0006-2960 DOI

M.Matzapetakis; P.Turano; E.C.Theil; I.Bertini (2007). 13C-13C NOESY spectra of a 480 kDa protein: solution NMR of ferritin. JOURNAL OF BIOMOLECULAR NMR, vol. 38, pp. 237-242, ISSN:0925-2738 DOI

L. Banci; I. Bertini; C. Luchinat; P. Turano (2006). Special cofactors and metal clusters. In: I. Bertini, H.B. Gray, J. S. Valentine, E.I. Stiefel. Biological Inorganic Chemistry: Structure & Reactivity, pp. 43-56, Sausalito (CA): University Science Books, ISBN:9781891389436.

J.S. Magyar; P. Turano (2006). Structural zinc-binding domains. In: I. Bertini, H.B. Gray, J.S. Valentine, E.I. Stiefel. Biological Inorganic Chemistry: Structure & Reactivity, pp. 628-634, Sausalito (CA): University Science Books, ISBN:9781891389436.

M.Stola;F.Musiani;S.Mangani;P.Turano;N.Safarov;B.Zambelli;S.Ciurli (2006). The nickel site of Bacillus pasteurii UreE, a urease metallo-chaperone, as revealed by metal-binding studies and X-ray absorption spectroscopy. BIOCHEMISTRY, vol. 45, pp. 6495-6509, ISSN:0006-2960 DOI

I. Bertini; S. Stagni; P. Turano (2006). Inorganic biochemistry. In: na. Encyclopedia of Life Support System, pp. na-na, Oxford: Eolss Publishers, Oxford ,UK.

L. Banci; I. Bertini; C. Luchinat; P. Turano (2006). Electron transfer proteins. In: I. Bertini, H.B. Gray, J.S. Valentine, E.I. Stiefel. Biological Inorganic Chemistry: Structure & Reactivity, pp. 229-261, Sausalito (CA): University Science Books, ISBN:9781891389436.

F.Arnesano; L.Banci; I.Bertini; F.Capozzi; S.Ciofi-Baffoni; S.Ciurli; C.Luchinat; S.Mangani; A.Rosato; P.Turano; M.S.Viezzoli (2006). An Italian contribution to structural genomics: understanding metalloproteins. COORDINATION CHEMISTRY REVIEWS, vol. 250, pp. 1419-1450, ISSN:0010-8545 DOI

I. Bertini; P. Turano (2006). Metal cofactors and their ligands for protein stability and folding. In: I. Bertini, H.B. Gray, J.S. Valentine, E.I. Stiefel. Biological Inorganic Chemistry: Structure & Reactivity, pp. 31-41, Sausalito (CA): University Science Books, ISBN:9781891389436.

C.Caillet-Saguy; M.Delepierre; A.Lecroisey; I.Bertini; M.Piccioli; P.Turano (2006). Direct-detected 13C NMR to investigate the iron(III) hemophore HasA.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128, pp. 150-158, ISSN:0002-7863 DOI

E.LIBRALESSO; K.NERINOVSKI; G.PARIGI; P.TURANO (2005). 1H nuclear magnetic relaxation dispersion of Cu,Zn superoxide dismutase in the native and guanidinium-induced unfolded forms.. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 328, pp. 633-639, ISSN:0006-291X DOI

B. ZAMBELLI;M. STOLA;F. MUSIANI;K. DE VRIENDT;B. SAMYN; B. DEVREESE;J. VAN BEEUMEN; P. TURANO;A. DIKIY;D.A. BRYANT; S. CIURLI (2005). UreG, a chaperone in the urease assembly process, is an intrinsically unstructured GTPase that specifically binds Zn2+.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, pp. 4684-4695, ISSN:0021-9258, American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824: DOI

L.Banci; I.Bertini; N.D'Amelio; E.Gaggelli; E.Libralesso; I.Matecko; P.Turano; J.S.Valentine (2005). Fully metallated S134N Cu,Zn-superoxide dismutase displays abnormal mobility and intermolecular contacts in solution. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, pp. 35815-35821, ISSN:0021-9258 DOI

I. Bertini; V. Calderone; M. Cosenza; M. Fragai; Y. M. Lee; C. Luchinat; S. Mangani; B. Terni; P. Turano (2005). Conformational variability of matrix metalloproteinases: beyond a single 3D structure. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, pp. 5334-5339, ISSN:0027-8424 DOI Accesso ONLINE all'editore

S.J.Berners-Price; I.Bertini; H.B.Gray; G.A.Spyroulias; P.Turano (2004). The stability of the cytochrome c scaffold as revealed by NMR spectroscopy. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 98, pp. 814-823, ISSN:0162-0134, Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680: DOI

I.Bertini; P.Turano; P.R.Vasos; A.Bondon; S.Chevance; G.Simonneaux (2004). Cytochrome c and SDS: a molten globule protein with altered axial ligation. JOURNAL OF MOLECULAR BIOLOGY, vol. 336, pp. 489-496, ISSN:0022-2836 DOI

L. Messori; F. Piccioli; C. Temperini; A.R. Bilia; F.F. Vincieri; M. Allegrozzi; P. Turano (2004). The reaction of artemisinin with hemin: a further insight into the mechanism. INORGANICA CHIMICA ACTA, vol. 357, pp. 4602-4606, ISSN:0020-1693

I.Bertini; A.Rosato; P.Turano (2004). Cytochrome c folding/unfolding: a unifying picture. JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, vol. 8, pp. 238-245, ISSN:1088-4246, Soc Porphyrins & Phthalocyanin:6 Boulevard Gabriel, JPP Office, 21000 Dijon France:011 33 3 80396118, EMAIL: jpp@u-bourgogne.fr, Fax: 011 33 3 80396869:

P. TURANO (2004). Insights into partially folded or unfolded States of metalloproteins from nuclear magnetic resonance.. INORGANIC CHEMISTRY, vol. 43, pp. 7945-7952, ISSN:0020-1669, American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671: DOI

M. Assfalg; I. Bertini; A. Dolfi; P. Turano; A.G. Mauk; F.I. Rosell;H.B. Gray (2003). Structural Model for an Alkaline Form of Ferricytochrome c. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, pp. 2913-2922, ISSN:0002-7863

M.ASSFALG; I.BERTINI; P.TURANO; A.G.MAUK; J.R.WINKLER; H.B.GRAY (2003). 15N-1H residual dipolar coupling analysis of native and alkaline-K79A S. cerevisiae cytochrome c.. BIOPHYSICAL JOURNAL, vol. 84, pp. 3917-3923, ISSN:0006-3495

M. Assfalg; L. Banci; I. Bertini; P. Turano; P.R.Vasos (2003). Superoxide dismutase folding/unfolding pathway: role of the metal ions in modulating structural and dynamical features.. JOURNAL OF MOLECULAR BIOLOGY, vol. 330, pp. 145-158, ISSN:0022-2836 DOI

P. Turano; G. Battaini; L. Casella (2003). Validation of paramagnetic cross correlation rates for solution structure determination of high spin iron(III) heme proteins. CHEMICAL PHYSICS LETTERS, vol. 373, pp. 460-463, ISSN:0009-2614

I. Bertini; C. Luchinat; P. Turano; G. Battaini; L. Casella (2003). The magnetic properties of myoglobin as studied by NMR spectroscopy. CHEMISTRY-A EUROPEAN JOURNAL, vol. 9, pp. 2316-2322, ISSN:0947-6539 DOI

I. BARTALESI; I. BERTINI; G. KAUSHIK; A. ROSATO; P. TURANO (2002). The unfolding of oxidized c-type cytochromes: the instructive case of B. pasteurii.. JOURNAL OF MOLECULAR BIOLOGY, vol. 321, pp. 693-701, ISSN:0022-2836

M. ASSFALG; I. BERTINI; M. BRUSCHI; C. MICHEL; P. TURANO (2002). The metal reductase activity of some multiheme cytochromes c: NMR structural characterization of the reduction of chromium(VI) to chromium(III) by cytochrome c7.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, pp. 9750-9754, ISSN:0027-8424

M. Assfalg; I. Bertini; P. Turano; M. Bruschi; M.C. Durand; M.T. Giudici-Orticoni; A. Dolla (2002). A quick solution structure determination of the fully oxidized double mutant K9-10A cytochrome c 7 from Desulfuromonas acetoxidans and mechanistic implications.. JOURNAL OF BIOMOLECULAR NMR, vol. 22, pp. 107-122, ISSN:0925-2738, Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254:

F. Arnesano;L. Banci;I. Bertini;I. Felli;P. Hajieva;D. Koulougliotis;C. Luchinat;A. Rosato;G. Spyroulias;P. Turano;M. S. Viezzoli (2001). Cytochrome b5. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 86, pp. 495-495, ISSN:0162-0134

BANCI L; I. BERTINI; BR. BRANCHINI; P. HAJIEVA; G.A. SPYROULIAS; P. TURANO (2001). Dimethyl Propionate Ester Heme- Containing Cytochrome b5: Structure and Stability.. JBIC, vol. 6, pp. 490-503, ISSN:0949-8257, Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229:

BARKER P.D.; I. BERTINI; R. DEL CONTE; S.J. FERGUSON; P. HAJIEVA; P. TOMLINSON; P. TURANO; M.S. VIEZZOLI (2001). A further clue to understanding the mobility of mitochondrial yeast cytocrome c: a 15N T1p investigation of the oxidized and reduced species.. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 268, pp. 4468-4476, ISSN:0014-2956, Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205:

Banci L.; Bertini I.; Luchinat C.;Turano P. (2000). Solution Structures of Hemoproteins. In: Kadish, K.M., Smith, K.M. and Guilard, R.. The Porphyrin Handbook, pp. 323-350, San Diego: Academic Press.

I. BERTINI; C. LUCHINAT; P. TURANO (2000). 15N chemical shift changes in cytochrome b5: redox-dependent vs. guanidinium chloride-induced changes. JBIC, vol. 5, pp. 761-764, ISSN:0949-8257, Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229:

I. Bertini; P. Turano (2000). Effects of folding on metalloprotein active sites. CHEMTRACTS, vol. 13, pp. 388-391, ISSN:1431-9268

ASSFALG M.; L. BANCI; I. BERTINI; M. BRUSCHI; M.T. GIUDICI-ORTICONI; P. TURANO (1999). A proton-NMR investigation of the fully reduced cytochrome c7 from Desulfuromonas acetoxidans: comparison between the reduced and the oxidized forms. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 266, pp. 634-643, ISSN:0014-2956, Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205:

I. BERTINI; A. ROSATO; P. TURANO (1999). Solution structure of paramagnetic metalloproteins.. PURE AND APPLIED CHEMISTRY, vol. 71, pp. 1717-1725, ISSN:0033-4545, Editore attuale:INT UNION PURE APPLIED CHEMISTRY, 104 TW ALEXANDER DR, PO BOX 13757, RES TRIANGLE PK, USA, NC, 27709-3757 Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205:

BANCI L; I. BERTINI; HUBER J.G; SPYROULIAS G.A; TURANO P (1999). Solution structure of reduced horse heart cytochrome c. JBIC, vol. 4, pp. 21-31, ISSN:0949-8257, Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229:

I.Bertini; A.Clemente; I.Rombeck, A. Rosato, P. Turano, B. Lippert, F. Quadrifoglio (1999). Three-dimensional solution structures of two DNA dodecamers through full relaxation matrix analysis. MAGNETIC RESONANCE IN CHEMISTRY, vol. 37, pp. 564-572, ISSN:0749-1581

L. Banci; S. J. Berners-Price; I. Bertini; V. Clementi; C. Luchinat; G. A. Spyroulias; P. Turano (1998). Water-protein interaction in native and partially unfolded equine cytochrome c. MOLECULAR PHYSICS, vol. 95, pp. 797-808, ISSN:0026-8976

L. Banci; I. Bertini; G. A. Spyroulias; P. Turano (1998). The conformational flexibility of oxidized cytochrome c studied through its interaction with NH3 and at high temperatures. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, vol. issue 5, pp. 583-591, ISSN:1434-1948

M. Assfalg; L. Banci; I. Bertini; M. Bruschi; P. Turano (1998). 800 MHz H-1 NMR solution structure refinement of oxidized cytochrome c(7) from Desulfuromonas acetoxidans. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 256, pp. 261-270, ISSN:0014-2956

L. Banci; I. Bertini; T. Reddig; P. Turano (1998). Monitoring the conformational flexibility of cytochrome c at low ionic strength by H-1-NMR spectroscopy. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 256, pp. 271-278, ISSN:0014-2956

Banci L.; Bertini I.; Turano P. ; Luchinat C. (1998). The solution structure of redox proteins and beyond.. In: Canters, G.W. and Vijgenboom, E.. Biological electron transfer chains: genetics and mode of operation, pp. 225-238, Dordrecht: Attuale:KLUWER ACADEMIC PUBL, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ ACM / Association for Computing Machinery:1515 Broadway, 17th Floor:New York, NY 10036:(212)869-7440, EMAIL: acmhelp@hq.acm.org, INTERNET: http://www.acm.org, Fax: (212)944-1318.

L. Banci; G. GoriSavellini; P. Turano (1997). A molecular dynamics study in explicit water of the reduced and oxidized forms of yeast iso-1-cytochrome c--solvation and dynamic properties of the two oxidation states. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 249, pp. 716-723, ISSN:0014-2956

L.Banci; I.Bertini; G.GoriSavellini; A.Romagnoli; P.Turano; M.A.Cremonini; C.Luchinat; H.B.Gray (1997). Pseudocontact shifts as constraints for energy minimization and molecular dynamics calculations on solution structures of paramagnetic metalloproteins. PROTEINS, vol. 29, pp. 68-76, ISSN:0887-3585

L.Banci; I.Bertini; H.B.Gray; C.Luchinat; T.Reddig; A.Rosato; P.Turano (1997). Solution structure of oxidized horse heart cytochrome c. BIOCHEMISTRY, vol. 36, pp. 9867-9877, ISSN:0006-2960

L.Banci; I.Bertini; K.L.Bren; H.B.Gray; P.Sompornpisut; P.Turano (1997). Solution structure of oxidized Saccharomyces cerevisiae iso-1-cytochrome c. BIOCHEMISTRY, vol. 36, pp. 8992-9001, ISSN:0006-2960

L.Banci; I.Bertini; K.L.Bren; M.A.Cremonini; H.B.Gray; C.Luchinat; P.Turano (1996). The use of pseudocontact shifts to refine solution structures of paramagnetic metalloproteins: Met80Ala cyano-cytochrome c as an example. JBIC, vol. 1, pp. 117-126, ISSN:0949-8257

P.Baistrocchi; L.Banci; I.Bertini; P.Turano; K.L.Bren; H.B.Gray (1996). Three-dimensional solution structure of Saccharomyces cerevisiae reduced iso-1-cytochrome c. BIOCHEMISTRY, vol. 35, pp. 13788-13796, ISSN:0006-2960

L. Banci; A. Rosato; P. Turano (1996). Can the axial ligand strength be monitored through spectroscopic measurements?. JBIC, vol. 1, pp. 364-367, ISSN:0949-8257

L. Banci; I. Bertini; M. Bruschi; P. Sompornpisut; P. Turano (1996). NMR characterization and solution structure determination of the oxidized cytochrome c7 from Desulfuromonas acetoxidans.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, pp. 14396-14400, ISSN:0027-8424

L. BANCI; I. BERTINI; K.L. BREN; H.B. GRAY; P. SOMPORNPISUT; P. TURANO (1995). 3-DIMENSIONAL SOLUTION STRUCTURE OF THE CYANIDE ADDUCT OF A MET80ALA VARIANT OF SACCHAROMYCES-CEREVISIAE ISO-1-CYTOCHROME-C - IDENTIFICATION OF LIGAND-RESIDUE INTERACTIONS IN THE DISTAL HEME CAVITY. BIOCHEMISTRY, vol. 34, pp. 11385-11398, ISSN:0006-2960

P.TURANO; J.C.FERRER; M.R.CHEESMAN; A.J.THOMSON; L.BANCI; I.BERTINI; A.G.MAUK (1995). pH, Electrolyte, and Substrate-Linked Variation in Active Site Structure of the Trp51Ala Variant of Cytochrome c Peroxidase. BIOCHEMISTRY, vol. 34, pp. 13895-13905, ISSN:0006-2960

L.BANCI; I.BERTINI; K.L.BREN; H.B.GRAY; P.TURANO (1995). pH-dependent equilibria of yeast Met80Ala-iso-1-cytochrome c probed by NMR spectroscopy: a comparison with the wild-type protein. CHEMISTRY & BIOLOGY, vol. 2, pp. 377-383, ISSN:1074-5521

K.L.BREN; H.B.GRAY; L.BANCI; I.BERTINI; P.TURANO (1995). Paramagnetic 1H NMR spectroscopy of the cyanide derivative of Met80Ala-iso-1-cytochrome c.. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 117, pp. 8067-8073, ISSN:0002-7863

J. C. FERRER; P. TURANO; L. BANCI; I. BERTINI; I. K. MORRIS; K. M. SMITH; M. SMITH; A. G. MAUK (1994). Active-Site Coordination Chemistry Of The Cytochrome-C Peroxidase Asp235ala Variant - Spectroscopic And Functional-Characterization. BIOCHEMISTRY, vol. 33, pp. 7819-7829, ISSN:0006-2960, Amer Chemical Soc:

L. Banci; I. Bertini; I. C. Kuan; M. Tien; P. Turano; A. J. Vila (1993). NMR investigation of isotopically labeled cyanide derivatives of lignin peroxidase and manganese peroxidase.. BIOCHEMISTRY, vol. 32, pp. 13483-13489, ISSN:0006-2960

L. BANCI; I. BERTINI; C. LUCHINAT; L. MESSORI; P. TURANO (1993). Frontiers in 2D NMR of paramagnetic metalloproteins. APPLIED MAGNETIC RESONANCE, vol. 4, pp. 461-476, ISSN:0937-9347

I.Bertini; P.Turano; A.J.Vila (1993). NMR of paramagnetic metalloproteins. CHEMICAL REVIEWS, vol. 93, pp. 2833-2932, ISSN:0009-2665

L. Banci; I. Bertini; T. Bini; M. Tien; P. Turano (1993). Binding of horseradish, lignin, and manganese peroxidases to their respective substrates.. BIOCHEMISTRY, vol. 32, pp. 5825-5831, ISSN:0006-2960

L. BANCI; I. BERTINI; P. TURANO; M. VICENS OLIVER (1992). Noe And 2-Dimensional Correlated H-1-Nmr Spectroscopy Of Cytochrome-C' From Chromatium-Vinosum. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 204, pp. 107-112, ISSN:0014-2956

L. BANCI; I. BERTINI; E. A. PEASE; M. TIEN; P. TURANO (1992). H-1-Nmr Investigation Of Manganese Peroxidase From Phanerochaete-Chrysosporium - A Comparison With Other Peroxidases. BIOCHEMISTRY, vol. 31, pp. 10009-10017, ISSN:0006-2960

I. BERTINI; F. CAPOZZI; C. LUCHINAT; P. TURANO (1991). Applications Of Cosy To Paramagnetic Heme-Containing Systems. JOURNAL OF MAGNETIC RESONANCE, vol. 95, pp. 244-252, ISSN:0022-2364

L. BANCI; I. BERTINI; P. TURANO (1991). An investigation of Cu2Zn2 superoxide dismutase and its Ile-137 mutant at high pH. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, vol. 19, pp. 141-146, ISSN:0175-7571

L. BANCI; I. BERTINI; P. TURANO; J. C. FERRER; A. G. MAUK (1991). Comparative H-1-Nmr Study Of Ferric Low-Spin Cytochrome-C Peroxidase And Horseradish-Peroxidase. INORGANIC CHEMISTRY, vol. 30, pp. 4510-4516, ISSN:0020-1669

I. BERTINI; A. LEPORI; C. LUCHINAT; P. TURANO (1991). Role Of Arg-143 In Human Cu2zn2sod Studied Through Anion Binding. INORGANIC CHEMISTRY, vol. 30, pp. 3363-3364, ISSN:0020-1669

L. BANCI; I. BERTINI; P. TURANO; M. TIEN; T. K. KIRK (1991). Proton Nmr Investigation Into The Basis For The Relatively High Redox Potential Of Lignin Peroxidase. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 88, pp. 6956-6960, ISSN:0027-8424

C. Luchinat;S. Steuernagel;P. Turano (1990). APPLICATION OF 2D NMR TECHNIQUES TO PARAMAGNETIC SYSTEMS. INORGANIC CHEMISTRY, vol. 29, pp. 4351-4353, ISSN:0020-1669

L.Banci; I.Bertini; C.Luchinat; A.Scozzafava; P.Turano (1989). Binding of fluoride to copper zinc superoxide dismutase.. INORGANIC CHEMISTRY, vol. 28, pp. 2377-2381, ISSN:0020-1669

L. BANCI; I. BERTINI; C. LUCHINAT; M. PICCIOLI; A. SCOZZAFAVA; P. TURANO (1989). H-1 Noe Studies On Dicopper(II) Dicobalt(II) Superoxide-Dismutase. INORGANIC CHEMISTRY, vol. 28, pp. 4650-4656, ISSN:0020-1669, Amer Chemical Soc:

Paola TURANO

Biography

Paola Turano is full professor of General and Inorganic Chemistry at the University of Florence. Her research activity is mainly dedicated to NMR in Life Sciences. She has a long term experience in the development and application of NMR methods to inorganic systems of biological relevance, with a special focus on heme proteins and ferritins. Since 2008, Paola Turano expanded her research interest to include NMR-based metabolomics. In this field, she brought an original contribution in the pre-analytics sector (developed through the FP7 SPIDIA and H2020 SPIDIA4P projects), which led to her involvement in CEN and ISO technical committees for the development of pre-analytical standards for metabolomics. Since 2020 active research is also ongoing on the profiling of metabolites and liproproteins in serum or plasma specimens from COVID-19 subjects.

Paola TURANO

Curriculum

Place & date of birth/Luogo e data di nascita: Firenze 05/07/1964

Nationality/Nazionalità: Italian/Italiana

Address/Indirizzo:

CERM – Via. Sacconi, 6

Dipartimento di Chimica Ugo Schiff – Via della Lastruccia 3-13

Università degli Studi di Firenze

50019 Sesto Fiorentino (Firenze) Italia

e-mail:turano@cerm.unifi.it,paola.turano@unifi.it

Education/Formazione:

1993 – Ph.D. in Chemical Sciences/Dottorato di Ricerca in Scienze Chimiche – Università di Firenze

1989 – Degree in Chemistry/Laurea in Chimica (110/110 cum laude) – Università di Firenze

Professional Appointments/Incarichi professionali

September 2021-present Full professor – Univ. of Florence

November2002–August 2021 Associate Professor – Univ. ofFlorence

October1997–October2002 Researcher at the Faculty of Sciences – Univ. of Florence

June1996–September1997 Research contract –Dept. of Chemistry –Univ. of Florence

May1994-April1996 Postdoctoral fellowship – Univ. ofFlorence

November1993-January1994 Visiting Associate in Chemistry – California Institute of Technology

Management activities (University of Florence)/Attività di gestione (Università di Firenze)

Support for the management of research centers and services:

2023-ongoing President, Magnetic Resonance Center (CERM)

2022-2024 Member of the Steering and Self-evaluation Committee, Department of Chemistry

2017-2023 Member of the Scientific Council of the Magnetic Resonance Center (CERM)

2017-2023 Scientific Director and President of the Scientific Committee, da Vinci European Biobank

2013-2015 Member of the Board of the Chemistry Department

2010-2014 Member of the Scientific Council of the Magnetic Resonance Center (CERM)

1998-2000 Member of the Board of Chemistry Department

Coordination of teaching activities:

2016-2024 Chair of the Bachelor's Degree Course in Biotechnology

2015-2022 Chair of the Master's Degree Course in Molecular Biotechnology

2001-ongoing Member of the Board of Teachers of the International Doctorate in Structural Biology / Mechanistic and Structural Systems Biology

2004-ongoing Teaching Committee, Master's Degree in Molecular Biotechnology

2001-ongoing Teaching Committee, Bachelor's Degree in Biotechnology (delegate for the biomolecular curriculum)

Offices held/Incarichi presso società o istituzioni scientifiche

National/Nazionali:

2024-ongoing Member of the Executive Board, Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine

2016-2019 Vice-Chair, Gruppo Italiano Discussione Risonanze Magnetiche(GIDRM)

2015-2016 Treasurer, Gruppo Italiano Discussione Risonanze Magnetiche (GIDRM)

2014-2015 Vice-Chair, Gruppo Italiano Discussione Risonanze Magnetiche (GIDRM)

2014-2017 Chair of the scientific committee, da Vinci EuropeanBiobank of the FiorGen Foundation

2009-2013 Scientific committee member, da Vinci European Biobank of the FiorGen Foundation

International/Internazionali

2024-ongoing Member of the SBIC nomination committee

2012-2014 Chair, Division of Chemistry in Life Sciences ofEuCheMS

2008-2012 Council member, Society of Biological Inorganic Chemistry (SBIC)

Awards/Premi

“GIDRM/GIRM Gold Medal 2023”

“Raffaello Nasini Medal 2003” of the Inorganic Chemistry Division of the Italian Chemical Society

European CEN-CENELEC Project Award 2021 (Project Award to the SPIDIA4P consortium)

Research funding/Finanziamenti (bandi competitivi)

Project/Progetto	Duration/Durata (months/mesi)	Role/Ruolo
Predictive modeling of Omics biomarkers in temporal lobe Epilepsy: a comprehensive multidisciplinary and Translational Approach from rodents to humans (POETA) – PRIN 2022	24	PI of Research Unit
A Flexible antibody-drug conjugate Approach for Innovative antiviral THerapy (FAITH) – PRIN 2020	36	PI of Research Unit
COMETA - Studio del fingerprint metabolomico dei pazienti affetti da Covid 19 per un accurato inquadramento diagnostico, prognostico e terapeutico - BANDO RICERCA COVID-19 TOSCANA	24	PI of Research Unit
Sviluppo di nanodispositivi a base di ferritina per il trasporto mirato di farmaci e sonde per imaging - Fondazione Cassa di Risparmio di Firenze 2020.1519	12	PI
Advanced mass spectrometry tools for cancer research: novel applications in proteomics, metabolomics and nanomedicine (AIRC - Fondazione CR Firenze Multi - user Equipment Program Call for Proposals 2016	24	PI of Research Unit
SPIDIA4P “SPIDIA for personalized Medicine Standardization of Generic Preanalytical procedures for In-vitro diagnostics for personalized medicine” H2020	48	PI of Research Unit
Valutazione del tempo di vita dei campioni in biobanche di materiale biologico - Ente CRF 2013.0494	18	PI of Research Unit
Progetto RISE - Regione Toscana PAR FAS 2007-2013 – Realizzazione Centri di Competenza	36	PI of Research Unit
Farmaci innovativi per Malattie Neurodegenerative - FINDING - POR CREO FESR 2007-2013	24	PI of Research Unit
Controllo Qualità di campioni biologici conservati in biobanca – Ente CRF 2011.1073	12	PI
Realizzazione laboratori di biologia cellulare e molecolare (BioLab) - Ente CRF 2008.2026	12	PI
SPIDIA "Standardisation and improvement of generic pre-analytical tools and procedures for in-vitro diagnostics" HEALTH-F5-2008-222916	54	PI of Research Unit
"Ingegneria proteica e caratterizzazione strutturale di eme proteine per applicazioni bioelettroniche" - Progetto Finalizzato Biotecnologie	24	PI