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Nata a Firenze nel 1974, la Professoressa Eleonora Gambineri si è laureata in Medicina nel 1999 e si è specializzata in Pediatria nel 2006 presso l’Università di Firenze. Ha svolto attività di ricerca sui difetti congeniti del sistema immunitario presso l’Università di Washington e si è formata nel trapianto di cellule staminali presso l’Università di Newcastle. Dal 2004 al 2018 è stata ricercatrice e professore associato presso l’Università di Firenze, lavorando all’Ospedale Pediatrico Meyer. Dal 2018 è Professore Associato in Pediatria e responsabile dell’Unità di Immuno-Onco-Ematologia dello stesso ospedale. La sua ricerca si concentra su disordini ereditari della regolazione immunitaria, neoplasie pediatriche e malattie ematologiche. Autrice di circa 80 pubblicazioni scientifiche, ha contribuito attivamente per molti anni alla crescita della European Society for Immunodeficiencies e di altre organizzazioni. Crede fortemente nella collaborazione come chiave per il progresso della ricerca e della cura.
INFORMAZIONI PERSONALI
ELEONORA GAMBINERI
eleonora.gambineri@unifi.it
Skype ID: elegambis
Sesso F | Data di nascita 07/04/1974 | Nazionalità Italiana
SETTORE PROFESSIONALE Pediatria, Immunologia ed Ematologia Pediatrica
BIOMETRICA
POSIZIONE ATTUALE
ESPERIENZA PROFESSIONALE
ESPERIENZA
PROFESSIONALE ALL’ESTERO
ISTRUZIONE E FORMAZIONE
CAPACITA’ E COMPETENZE PERSONALI
Lingua madre
Italiano
Altre lingue
COMPRENSIONE
PARLATO
PRODUZIONE SCRITTA
Ascolto
Lettura
Interazione
Produzione orale
Inglese
C2
C1
2000-2001: corso avanzato di inglese presso il Wall Street Institute di Firenze
2001-2002: corso semestrale di inglese avanzato presso la University of Washington, Seattle, USA
Livelli: A1/A2: Utente base - B1/B2: Utente intermedio - C1/C2: Utente avanzato
Quadro Comune Europeo di Riferimento delle Lingue
Competenze comunicative
Possiedo buone competenze comunicative acquisite durante la mia esperienza di relatrice a congressi/simposi/corsi didattici sia nazionali che internazionali
Competenze organizzative e gestionali
Competenze informatiche
Ottima conoscenza ed utilizzo sia della piattaforma Windows che Mac, Microsoft Word, Power Point, Excel, posta elettronica, navigazione internet, SPSS, STATA, Open AI,
Area di interesse
Il mio percorso formativo e il mio principale interesse di ricerca si sono sempre concentrati sullo studio delle immunodeficienze primitive (PID), con particolare attenzione ai disturbi da disregolazione immunitaria. Parte della mia formazione si è svolta all'estero, presso centri di eccellenza (USA e UK), dove ho avuto modo di studiare sia gli aspetti clinici che molecolari delle PID, oltre alle opzioni terapeutiche (ad esempio, BMT/terapie cellulari). Questo mi ha aperto enormi possibilità di collaborazioni di ricerca fruttuose, ulteriormente arricchite dal mio impegno pluriennale nelle attività della European Society for Immunodeficiencies (ESID) dal 2006. La mia attività clinica e di ricerca degli ultimi 20 anni si è principalmente concentrata sulle PID, sulle malattie autoimmuni e sulla predisposizione al cancro. Ho partecipato a numerosi congressi internazionali e nazionali, presentando i miei dati di ricerca (tramite poster e comunicazioni orali) e come relatore invitato. Sono autore di numerosi articoli pubblicati su riviste scientifiche peer-review(https://www.ncbi.nlm.nih.gov/pubmed/?term=gambineri+e ) e di capitoli di libri in lingua inglese, oltre a diverse pubblicazioni su riviste nazionali. Inoltre, ho contribuito allo sviluppo di linee guida internazionali per la gestione immunologica della Sindrome da Delezione del Cromosoma 22q11.2 e di altri difetti dello sviluppo timico (DOI: 10.1007/s10875-024-01655-3). Attualmente, faccio parte di un comitato di esperti ESID che sta elaborando linee guida sulla vaccinazione per pazienti immunocompromessi (pubblicazione in corso).
Obiettivi
Altre competenze
1994-1998: Giocatrice di pallanuoto femminile (squadra Rari Nantes Florentia, serie C e B)
2014 - oggi: Maratoneta e mezzo maratoneta amatoriale (gare internazionali e nazionali); Abbott World Marathon Majors: Six Stars Finisher (2015-2024)
2024 - oggi: Competizioni di nuoto nella categoria Masters
ULTERIORI INFORMAZIONI
Fondi di Ricerca
Riconoscimenti e premi
Attività Didattica
Supervisione di Studenti Laureati e Ricercatori Post-Dottorato
Organizzazione di Meeting Scientifici
Attività di revisore per riviste scientifiche internazionali e grants
Attività editoriale
Referenze
Organizzazioni Professionali
Dal 2005 al 2024, ho supervisionato circa 42 studenti laureati e ricercatori post-dottorato, supportandoli nello sviluppo accademico, nella formazione alla ricerca e nella progressione della carriera nel campo della pediatria e dell’immunologia pediatrica.
- Pediatric Research (2009)
- Pediatric Allergy and Immunology (2009)
- The Pediatric Infectious Disease Journal (2010)
- Journal of Allergy and Clinical Immunology (dal 2013 ad oggi)
- Clinical Immunology (2014)
- Journal of Clinical Immunology (dal 2014 ad oggi)
- Frontiers Immunology and Paediatrics (dal 2015 ad oggi)
- Frontiers in Paediatrics, sezione Paediatric Haematology and Immunology (dal 2016 ad oggi)
- Expert Review of Clinical Immunology (2016)
- Paediatric Allergy, Immunology, and Pulmonology (2016)
- Journal of Clinical Immunology (2017)
- Frontiers in Immunology (dal 2017 ad oggi)
- Research Council of K.U.Leuven, proposta di ricerca del professor Xavier Bossuyt "Regolazione della risposta immunitaria allo Streptococcus pneumoniae incapsulato" (2012)
- Università di Modena e Reggio Emilia, proposta di ricerca del professor Carlo Salvarani "Metabolomica e analisi immunologica per rilevare l'interazione tra vie metaboliche e infiammatorie tra psoriasi e artrite psoriasica", Bando FAR 2021
Dal 2009 ad oggi: Pediatric Reports, membro del comitato editoriale
Dal 2022 ad oggi: Associate Editor Frontiers in Pediatrics (Pediatric Immunology)
▪ Dr. Troy R. Torgerson/Professor Hans D. Ochs, Seattle Children’s Hospital, University of Washington, Seattle, WA, USA.
▪ Prof. Raffaele Badolato, Università di Brescia, Brescia, Italia.
▪ Dr. Alberto Tommasini, IRCCS Burlo Garofalo, Trieste, Italia.
▪ Prof. Isabelle Meyts, Università di Leuven, Belgio.
▪ Prof. Stephan Ehl, Università di Freiburg, Center for Chronic Immunodeficiency – CCI.
▪ Prof. Andrew Gennery/Prof. Sophie Hambleton, Università di Newcastle upon Tyne, Regno Unito.
▪ Sergio D. Rosenzweig, NIH, USA.
▪ Kate Sullivan, Chief of Allergy Immunology, CHOP, USA.
▪ Jolan Walter, USF, Johns Hopkins All Children’s Hospital, St. Petersburg, USA.
▪ Prof. Franco Locatelli, Ospedale Pediatrico Bambino Gesù IRCSS, Roma, Italia.
▪ Prof. Frederic Rieux-Laucat, Imagine Institute, Parigi, Francia.
▪ Prof. Père Soler Palacín, Vall d’Hebron Institut de Recerca, Barcellona, Spagna.
▪ Prof. Qiang Pan-Hammarström, Karolinska Institutet, Stoccolma, Svezia.
▪ Prof. Elie Haddad, CHU Sainte-Justine, Università di Montreal, Montreal, Canada.
▪ Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP), Membro
▪ Clinical Immunology Society (CIS), Membro
▪ European Haematology Association (EHA), Membro
▪ European Society for Immunodeficiencies (ESID), Membro
▪ Board Member (2006-2008) as head of the ESID Junior WP
▪ Board Member (2008-2014) as ESID Treasurer
▪ Board Member (2014-2018) as head of the ESID Educational WP
▪ Board Member (2020-2024) as ESID Secretary
DATI PERSONALI
Io sottoscritta, professoressa Eleonora Gambineri, nata a Firenze il 07/04/1974, residente a Firenze in via Trieste, 50 consapevole delle responsabilità e delle sanzioni penali stabilite dalla legge per le false attestazioni e le mendaci dichiarazioni (art. 76 del D.P.R. 445/2000) DICHIARA sotto la propria responsabilità che le informazioni contenute nel presente curriculum vitae corrispondono a verità
Autorizzo il trattamento dei miei dati personali ai sensi del Decreto Legislativo 30 giugno 2003, n. 196 "Codice in materia di protezione dei dati personali”.
Il mio percorso e i miei interessi di ricerca si sono sempre concentrati sulle immunodeficienze primitive (PID), con un’attenzione particolare ai disordini da disregolazione immunitaria. Parte della mia formazione si è svolta presso centri di eccellenza negli Stati Uniti e nel Regno Unito, dove ho approfondito sia gli aspetti clinici che molecolari delle PID, oltre alle opzioni terapeutiche, come il trapianto di midollo osseo e le terapie cellulari. Queste esperienze hanno aperto ampie possibilità di collaborazione scientifica, ulteriormente rafforzate dal mio coinvolgimento attivo nella European Society for Immunodeficiencies (ESID), di cui faccio parte dal 2006.
Negli ultimi 25 anni, la mia attività clinica e di ricerca si è focalizzata principalmente sulle PID, l’autoimmunità e la predisposizione allo sviluppo di neoplasie. Ho partecipato a numerosi congressi nazionali e internazionali presentando i miei dati sia con poster che con comunicazioni orali, anche in qualità di relatrice invitata. Sono autrice di numerose pubblicazioni su riviste peer-reviewed (PubMed), e di capitoli di libri in lingua inglese e di diversi articoli su riviste nazionali.
Migliori lavori recenti (fino 2024)
Ecco la traduzione in italiano:
1."Sviluppo di linee guida cliniche per la Sindrome da delezione del cromosoma 22q11.2" (2024)– Pubblicazione di raccomandazioni internazionali sulla gestione dei difetti dello sviluppo timico.2. "Ruolo del sistema immunitario intestinale nel controllo della disregolazione immunitaria" – Studio dei fattori immunitari intestinali nella GvHD e nelle sindromi IPEX/IPX-like.3. "Citopenie autoimmuni come nuovo segnale di allarme per le immunodeficienze primitive"– Analisi delle citopenie come marcatori diagnostici delle PID.4. "Linfomi Non-Hodgkin pediatrici e immunodeficienze primitive" – Indagine sul contributo dei difetti immunitari allo sviluppo dei tumori pediatrici.5. "Errori congeniti dell’immunità correlati a STAT3" (2023) – Studio dei meccanismi patologici e dei target terapeutici nei disordini legati a STAT3/STAT1.
Legenda
Born in Florence in 1974, Professor Eleonora Gambineri earned her medical degree in 1999 and specialized in Pediatrics in 2006 at the University of Florence. She trained in immune system defects at the University of Washington and in stem cell transplantation at Newcastle University. From 2004 to 2018, she was a researcher and assistant professor at the University of Florence and worked at Meyer Pediatric Hospital. Since 2018, she has been Associate Professor in Pediatrics and heads the Immuno-Onco-Hematology Unit at Meyer Children’s Hospital. Her research focuses on inherited immune dysregulation disorders, pediatric neoplasms, and hematological diseases. Author of about 80 scientific publications, she serves on the board of the European Society for Immunodeficiencies and other organizations. She strongly believes collaboration is key to advancing medical research and care.
Sex F | Date of Birth 07/04/1974 | Nationality Italian
Professional Field Paediatrics, Paediatric Immunology, Haematology and Oncology
QUALIFICATION Medical Doctor; Paediatrician; Master in Paediatric Allergy and Immunology.
BIOMETRICS
▪ Official H Index: 33
▪ Total Citations: 5,059
▪ Average Citations/year (2014-2024): 340
▪ Scopus author id: 7801396916
▪ ORCID author id: 0000-0002-4676-6541
▪ RESEARCH ID author code: J-8747-2016
▪ PUBLICATIONS: https://www.ncbi.nlm.nih.gov/pubmed/?term=gambineri+e
EDUCATION
▪ November 2007: Selected Participant at CIS Summer School in Primary immunodeficiencies, Miami, USA
▪ September 2003: Selected Participant at ESID Summer School in Primary immunodeficiencies, Algavre, Portugal
▪ 2006-2008: University of Tor Vergata, Rome Italy, Master Degree in Paediatric Immunology
▪ 2000-2006: University of Florence, Department of Paediatrics/ Anna Meyer Children’s Hospital, Florence, Italy, Certification as Paediatrician
▪ 2000: National Medical Board, Italy
▪ 1993-1999: University of Florence, Florence, Italy, Doctorate in Medicine with highest honours
▪ 1993: High School Diploma (Classical education), Liceo Ginnasio “Dante”, Florence
CURRENT POSITION
▪ 2010 to date: Children’s BMT Unit, Department of Haematology/Oncology “Meyer Children’s Hospital, IRCCS, Florence, Italy
▪ 2018 to date: Associate Professor of Paediatrics (SC 06/G1, SSD MED/38, permanent position): University of Florence, Department of NEUROFARBA, Florence Italy.
▪ 2021 to date: Head of Immuno-haemato-oncology Unit, Department of Haematology/Oncology, Meyer Children’s Hospital, IRCCS, Florence, Italy
▪ 2021 to date: Search Coordinator IBMDR for the paediatric HSC transplant program, Meyer Children’s Hospital, IRCCS, Florence, Italy
PREVIOUS POSITIONS:
▪ 1996-2001: Research fellow in the Paediatric Immunology lab and in Primary Immunodeficiency Clinic, University of Florence, “Anna Meyer” University Children’s Hospital, Florence, Italy.
▪ 2003-2004: Researcher (time-contract): University of Florence, Florence Italy.
▪ 2005-2018: Researcher/Assistant Professor (permanent position): University of Florence, Florence Italy.
▪ 2013- 2014: Rare Diseases Coordinator/Facilitator, A.O.U. Meyer, Florence, Italy
PROFESSIONAL EXPERIENCE ABROAD
▪ 2001-2003: Fellowship, Paediatric Immunology: Professor Hans Ochs, University of Washington, Department of Paediatrics, Medical Center, Seattle, WA.
▪ 2009-2010: Clinical/Research attachment in Prof. Andrew Cant’s clinic and research program, Children’s Bone Marrow Transplantation Unit-Newcastle General Hospital, Newcastle upon Tyne, UK.
▪ 07/2010: "Honorary Observer Contract" at Great Ormond Street Children's Hospital (Dr. Paul Veys, BMT Unit), London, UK.
▪ 12/2010-12/2011: Appointed as Visiting Professor at Newcastle University, Newcastle upon Tyne, UK.
PERSONAL SKILLS AND COMPETENCES
Mother Tongue
Italian
Other Languages
COMPREHENSION
SPEAKING
WRITING
Listening
Reading
Spoken interaction
Spoken production
English
2000-2001: Advance English Course at Wall Street Institute, Florence
2001-2002: Advance English Course at University of Washington, Seattle, USA
Levels: A1/A2: Basic user - B1/B2: Independent user - C1/C2 Proficient user
Communication Skills
I have good communication skills acquired during my experience as a speaker at national and international conferences / symposia / educational courses
Organizational and management skills
▪ From 2006 to 2024, as a member of the executive board of the European Society for Immunodeficiencies, I participate in the organization of international congresses and educational courses
▪ From 2004 I coordinate a research laboratory team (now 2 research fellows, 1 senior biologist and PhD students) at the NEUROFARBA Department, University of Florence
▪ I have a valid network of international and national collaborations in both scientific and clinical fields of paediatric immunology and haemato-oncology
Field of Interest
Professional Goals
Other Skills
My background and strong research interest have always been revolved around primary immunodeficiency (PID), with particular focus on immune dysregulation disorders. I did part of my training abroad in preeminent centres (USA and UK) and I was involved in studying both clinical and molecular aspects of PID as well as treatment options (i.e. BMT/cellular therapies). This has opened enormous possibilities for fruitful collaborative research also enhanced by my longstanding involvement in the activities of the European Society for Immunodeficiencies (ESID) since 2006. My clinical and research activity during the past 20 years has been mainly focused on PID, autoimmunity and predisposition to cancer. I have participated to several international and national conferences presenting my research data (posters and orals) and as invited speaker. I am author of several manuscripts, in peer-reviewed papers (https://www.ncbi.nlm.nih.gov/pubmed/?term=gambineri+e), and chapters of books in English, besides several publications in national journals.
Moreover, I was involved in the development of international clinical practice guidelines for the immunological management of chromosome 22q11.2 Deletion Syndrome and other defects in thymic development (DOI: 10.1007/s10875-024-01655-3) and I am currently part of an ESID expert committee that is developing vaccination guidelines for immunocompromised patients (pending publication).
To unravel congenital Immune defects in haematologic diseases.
To define the role of the immune system in development and progression of pediatric cancer.
Experience in cellular based therapies for malignant and non-malignant diseases.
To Explore the mechanisms of immune reconstitution post allogeneic HSCT.
1994-1998: Waterpolo player (Rari Nantes Florentia, C and B division)
2014 to date: amateur marathon and half-marathon runner (international and national races); Abbott World Marathon Majors: Six Stars Finisher (2015-2024)
2024 to date: swimming competitions in Masters category
ADDITIONAL INFORMATIONS
Research Grants
Awards and Honours
Teaching
Supervision of graduate students and postdoctoral fellows
Organisation of scientific meetings
Reviewing Activities
Editorial Boards
Collaborations
Professional Organizations
▪ 12/2004 and 07/2007: Telethon Research Grant: “From FOXP3 mutation to IPEX: genotype-phenotype, pathogenetic mechanisms and therapeutic options” (2004-2006) and (2007-2010)
▪ 04/2005: MIUR-Cofin 2005 (Italian National Institute of research and education) research grant: “Innovative approaches on gene therapy for neurological and immunological genetic diseases” (2006-2008)
▪ 12/ 2008: Health Ministry Research Grant for Young Investigators: “HLA-G: a new tolerogenic marker for tolerance induction mediated by regulatory T cells” (2008-2010)
▪ 03/2013: Jeffrey Modell Foundation Specific Defect Research Grant: “Role of gut immune system in controlling immune dysregulation: acute gut GvHD and IPEX/IPEX-like syndromes as models” (2013-2015)
▪ 12/2013: Health Ministry Research Grant for Young Investigators: “Role of gut environment in the immune reconstitution after hematopoietic stem cell transplantation (HSCT)” (GR-2011-02349759) (2014-2017)
▪ 09/2014: Ente Cassa di Risparmio di Firenze 2014 Research Grant: “Ruolo del sistema immunitario intestinale nel controllo delle immunodisregolazioni: malattia del trapianto verso l'ospite sindromi IPEX e “IPEX-like” come modelli di studio” (2014-2015)
▪ 12/2017: MIUR-Cofin 2016 (Italian National Institute of Research and Education) research grant: “From allergic and autoimmune diseases to immune-dysregulated disorders: clinical, immunological, genetic characterization and proposal of diagnostic and therapeutic protocols (2018-2021)
▪ 01/2018: Jeffrey Modell Foundation Specific Defect Research Grant: “Autoimmune cytopenias as “new warning sign” of primary immunodeficiency disorders” (2018-2020)
▪ 09/2018 and 09/2020: Ente Cassa di Risparmio di Firenze 2018 Research Grant: “Citopenie autoimmuni come segno di immunodeficienza primitiva: approccio immunologico e molecolare per ottimizzare il percorso diagnostico-terapeutico” (2018-2019;2020-2021)
▪ 01/2022: Jeffrey Modell Foundation Specific Defect Research Grant: “Pediatric Non-Hodgkin lymphomas as new “pointer” of primary immunodeficiencies: focusing on immune defect-associated cancer” (2022-2024)
▪ 10/2023: PRIN 2022 (Italian Ministry of University and Research) research grant (2022W839, years 2023-2025): “STAT3-related inborn errors of immunity: unraveling disease mechanisms and potential targets”
▪ 07/2023: Fondazione Telethon-Cariplo Grant (GJC22072, years 2023-2025): “Unravelling the role of ZNF341 in Hyper IgE, STAT3- and STAT1-gain of function related inborn errors of immunity”
▪ 12/2023: European Joint Program on Rare Disease 2023 (coordinator of an international multicenter study 2024-2027): “The interplay between Inborn Error of Immunity and blood disorders: unravelling immune defects behind common haematological diseases”; IEI-HAEM Consortium (Coordinator: E. Gambineri, Italy; Partners: Frédéric Rieux-Laucat, France, Pere Soler Palacín, Spain, Elie Haddad and Vincent-Philippe Lavallée, Canada, Maria Teresa Voso, Italy, Qiang Pan-Hammarström, Sweeden)
▪ 01/ 2004: Elected as the head of the European ESID registry for IPEX syndrome, serving as "Head of the Steering Committee."
▪ 12/ 2005: Elected as co-lead of the IPEX Study Protocol within the AIEOP Strategic Study Committee on Primary Immunodeficiencies.
▪ 06/2006: Invited to participate in the European Primary Immunodeficiencies Consensus Conference, Frankfurt, Germany, June 19–20, 2006.
▪ 2006-2018: ESID Board Member with the following roles: Head of ESID Juniors Working Party (2006-2008), ESID Treasurer (2008-2014), Head of Educational Working Party (2014-2018)
▪ 2009: Appointed guest editor for a multi-author review on "Heritable Immunodeficiencies" for the journal *Cellular and Molecular Life Sciences (CMLS)*.
▪ December 1, 2011: Served as a Telethon researcher testimonial at the event held in the Salone dei Cinquecento at Palazzo Vecchio, Florence, during the 2011 Telethon Marathon.
▪ December 3, 2011: Served as a Telethon researcher testimonial at the event held at the Maliseti football field in Prato for a match between the "Prato City Councilors and Hospital Doctors" during the 2011 Telethon Marathon.
▪ 2012: Awarded with “Premio Giovani Ricercatori 2012 (Young Researcher Award)” Anna Meyer Children’s Hospital
▪ 2002-2019: Awarded with 9 Travel Grants to attend international meetings and Summer Schools (ESID Summer School, FOCIS, CIS Primary Immune Disorders Consortium Conference, AAAAI, CIS Annual Meeting Primary Immune Deficiency Diseases etc.)
▪ 2015: Elected by Baxalta/Shire as a member of the PID Management Steering Committee to develop and moderate clinical cases within the interactive workshop “Patient in Practice” at the IPIC Meeting 2015 and the ESID Meeting 2016.
▪ 2008-2025: invited speaker to several national and mostly international Conferences on Paediatric Immunology and Haematology (average 2-3/year in the past 10 years)
▪ 2018 and 2024: Elected as a member of the Health Council, Meyer University Hospital, IRCCS, Florence
▪ 2019 to date: Member of SIOPEN Immunotherapy Subcommittee
▪ 2020 to 2024: Secretary of ESID
▪ 2022 to 2024: Expert member (ESID representative) of Scree4Rare
▪ 11/2023: Participation as expert to Ad-hoc Expert Group (AHEG) meeting on Joenja (leniolisib) by Committee for Human Medicinal Products (CHMP)- European Medicines Agengy (EMA)
▪ 2023 to date: Member of the Education subcommittee of the EHA SWG on Pediatric Hematology
▪ 03/2024 to date: Member of the IPEX Clinical Expert Committee (IRIS RHU project for development of gene therapy)
▪ 2005 to present: faculty member of School of Medicine, School of Nurses, Physiotherapy School, Science of Primary Education School, and Paediatric Residency Program University of Florence
▪ Since 2025: Member of the Academic Board of the PhD program: Translational Research in Health Protection Sciences (41st cycle), managed by the PhD Office of the University of Florence.
▪ 2006 to 2022: Member of ESID Educational Committee and faculty member of ESID Summer Schools
▪ 2020 and 2024: Faculty member of the International Alliance of PID Societies (IAPIDS) Advance course on Primary Immunodeficiencies (February 2020 and 2024)
From 2005 to 2024, I have supervised approximately 42 graduate students and postdoctoral fellows, supporting their academic development, research training, and career progression in the field of paediatrics and paediatric immunology.
▪ 2010: Meeting President of the ESID Junior Educational Workshop, (January 11-12, 2010, Florence, Italy)
▪ 2012: Meeting President of the 15th Biennial Meeting of ESID (October 3-6, 2012, Florence, Italy)
▪ 2008-2018 and 2020-2025: Member of the Scientific Committee for the organization of the annual and biennial ESID Congresses (2008:'s-Hertogenbosch, The Netherlands (October 16-19); 2010: Istanbul, Turkey (October, 6-9); 2012: Florence, Italy (October 3-6); 2014: Prague, Czech Republic (October 29 – November 1); 2016: Barcelona, Spain (September 21-24); 2017: Edinburgh, United Kingdom (September 11-14); 2018: Lisbon, Portugal (October 24-27); 2021: Online (September 27-29); 2022: Gothenburg, Sweden (October 12-15); 2024: Marseille, France (October 16-19); 2025: ESID-EHA-SIOPE Focused Symposium (November 18-20)
▪ 2025: Meeting President of the First international meeting of the IEI-Haem Consortium (January 24, 2025, Florence, Italy)
Referee for peer reviewed journals: Pediatric Research (2009); Pediatric Allergy and Immunology (2009); The Pediatric Infectious Disease Journal (2010); Journal of Allergy and Clinical Immunology (from 2013 to date); Clinical Immunology (2014); Journal of Clinical Immunology (from 2014 to date); Frontiers Immunology and Paediatrics (from 2015 to date); Frontiers in Paediatrics, section Paediatric Haematology and Immunology (from 2016 to date); Expert Review of Clinical Immunology (2016); Paediatric Allergy, Immunology, and Pulmonology (2016); Journal of Clinical Immunology (2017); Frontiers in Immunology (2017 to date);
Scientific Evaluator for research grants: Research Council of K.U.Leuven, Research proposal by professor Xavier Bossuyt"; Regulation of the immune response to encapsulated Streptococcus pneumoniae " (2012); University of Modena Reggio Emilia, Research Proposal by professor Carlo Salvarani “Metabolomics and immunological analysis to detect metabolic and inflammatory pathways interaction between psoriasis and psoriatic arthritis”, Bando FAR 2021;
Review panel member of the HDR Committee for Marianna Parlato’s Defence, University of Paris, November 23, 2021
2009 to date: Pediatric Reports, Member of Editorial Board
2022 to date: Associate Editor Frontiers in Pediatrics (Pediatric Immunology)
▪ 05-07/2004: Collaborative work in Professor Maria Grazia Roncarolo’s laboratory, San Raffaele Telethon Institute for Gene therapy (HSR-TIGET), Milan, Italy.
▪ 01/2005: Collaborative work in Professor Luigi D. Notarangelo’s clinic, Department of Paediatrics, University of Brescia, Brescia, Italy.
▪ 06-09/2005; 08/2008; 02-03/2017: Collaborative work in Dr Troy R. Torgerson/Professor Hans D. Ochs’ lab, Seattle Children’s Hospital, University of Washington, Seattle, WA, USA.
▪ 01/2013-12/2014: Collaboration with Department of Foetal and Neonatal Medicine: Rare Diseases, "Anna Meyer" University Children's Hospital, Florence, Italy.
▪ Major collaborators:
– Dr Troy R. Torgerson/Professor Hans D. Ochs’ lab, Seattle Children’s Hospital, University of Washington, Seattle, WA, USA.
– Prof. Raffaele Badolato, University of Brescia, Brescia, Italy
– Dr. Alberto Tommasini, IRCCS Burlo Garofalo, Trieste, Italy
– Prof. Isabelle Meyts, University of Leuven, Belgium
– Prof. Stephan Ehl, University of Freiburg, Center for Chronic Immunodeficiency – CCI
– Prof. Andrew Gennery/Prof. Sophie Hambleton, University of Newcastle upon Tyne, UK
– Sergio D. Rosenzweig, NIH, USA
– Kate Sullivan, Chief of Allergy Immunology, CHOP, USA
– Jolan Walter, USF, Johns Hopkins All Children's Hospital, St. Petersburg, USA
– Prof. Franco Locatelli, Ospedale Pediatrico Bambino Gesù IRCSS, Rome, Italy
– Prof. Frederic Rieux-Laucat, Imagine Institute, Paris, France
– Prof. Père Soler Palacín, Vall d’Hebron Institut de Recerca, Barcelona, Spain
– Prof. Qiang Pan-Hammarström, Karolinska Institutet, Stockholm, Sweden
– Prof. Elie Haddad, CHU Sainte-Justine, University of Montreal, Montreal, Canada
▪ Italian Society of Haematology/Oncology (AIEOP), Member
▪ Clinical Immunology Society (CIS), Member
▪ European Haematology Association (EHA), member
▪ European Society for Immunodeficiencies (ESID), Member
– Board Member (2006-2008) as head of the ESID Junior WP
– Board Member (2008-2014) as ESID Treasurer
– Board Member (2014-2018) as head of the ESID Educational WP
– Board Member (2020-2024) as ESID Secretary
I hereby authorize the use of my personal data in accordance to the GDPR 679/16 - "European regulation on the protection of personal data".
My background and research interests have consistently focused on primary immunodeficiencies (PID), with a particular emphasis on immune dysregulation disorders. As part of my training, I spent time at leading centers in the USA and UK, where I studied both the clinical and molecular aspects of PID, as well as treatment strategies such as bone marrow transplantation and cellular therapies. These experiences fostered valuable international collaborations, further strengthened by my active involvement with the European Society for Immunodeficiencies (ESID) since 2006.
Over the past 25 years, my clinical and research work has primarily addressed PID, autoimmunity, and cancer predisposition. I have presented my findings at numerous national and international conferences, both through oral presentations and posters, and as an invited speaker. I am the author of several peer-reviewed publications ([PubMed](https://www.ncbi.nlm.nih.gov/pubmed/?term=gambineri+e)) and book chapters in English, and several articles in national journals.
Best recent work (up to 2024):
1. "Development of clinical practice guidelines for chromosome 22q11.2 Deletion Syndrome" (2024) – Published international recommendations on managing defects in thymic development.2. "Role of gut immune system in controlling immune dysregulation" – Studied gut immune factors in GvHD and IPEX/IPEX-like syndromes.3. "Autoimmune cytopenias as a new warning sign of primary immunodeficiency disorders" – Explored cytopenias as diagnostic markers for PID.4. "Pediatric Non-Hodgkin lymphomas and primary immunodeficiencies" – Investigated immune defects' contribution to pediatric cancers.5. "STAT3-related inborn errors of immunity" (2023) – Elucidated disease mechanisms and therapeutic targets for STAT3/STAT1-related disorders.
