Augusto Vaglio consegue la laurea in Medicina e Chirurgia nel 2000 presso l’Università di Parma.Presso lo stesso ateneo completa nel 2005 il percorso di specializzazione in Nefrologia e, successivamente, nel 2009, il Dottorato di ricerca in Fisiopatologia dell’Insufficienza Renale.
Nel corso della sua formazione ha svolto attività di ricerca a livello internazionale: è stato post-doctoral fellow presso la Emory University di Atlanta, USA, e visiting fellow presso l’Università di Cambridge, Regno Unito.
Attualmente è Professore Associato di Nefrologia presso l’Università di Firenze e Direttore della Scuola di Specializzazione in Nefrologia dello stesso ateneo. Svolge la propria attività clinico-assistenziale presso l’Unità di Nefrologia dell’Azienda Ospedaliero-Universitaria Meyer IRCCS di Firenze.
EDUCAZIONE
-Liceo Scientifico "A. Vallone", Galatina (LE) (votazione finale 60/60) (1988-1993)
-Facoltà di Medicina e Chirurgia, Università di Parma, Italia (votazione finale 110/110 con lode) (1994-2000)
-Scuola di Specializzazione in Nefrologia, Università di Parma, Italia (votazione finale 50/50 con lode) (2000-2005)
-Borsa di studio post-dottorato, Lowance Center for Human Immunology, Emory University, Atlanta, USA (2005-2006)
-Dottorato di ricerca in Nefrologia, Università di Parma, Italia (2006-2009)
INSEGNAMENTO
-Professore presso la Scuola di Specializzazione in Nefrologia, Università di Parma (2005-2018)
-Professore a contratto, Scuola di Medicina, Università di Parma (2012-2018)
-Professore nel programma di Dottorato in Scienze della Salute, Scuola di Medicina, Università di Parma (2013 - attuale)
-Professore visitatore, Dipartimento di Medicina, Università di Cambridge, Regno Unito (giugno-luglio 2017)
-Professore Associato di Nefrologia, Università di Firenze (2018 - attuale)
-Direttore del Programma di Formazione Specialistica in Nefrologia, Università di Firenze (2019 - attuale)
POSIZIONE ATTUALE
-Professore Associato di Nefrologia, Università di Firenze, e medico-nefrologo, Ospedale Pediatrico Meyer IRCCS, Firenze
-Direttore della scuola di specializzazione in Nefrologia, Università di Firenze
AREE DI RICERCA
-Vasculiti ANCA-Associate
-Fibrosi retroperitoneale e malattia correlata alle IgG4
-Malattia di Erdheim-Chester
-Lupus eritematoso sistemico
DATI BIBLIOMETRICI
-286 articoli pubblicati su riviste internazionali in lingua inglese, con revisione tra pari
-Primo o ultimo autore in 145 dei 286 articoli
-h-index: 65 (Scopus)
-Citazioni: 14.037 (Scopus)
GRANT
-PI senior del progetto “A new comprehensive approach to predict long-term prognosis in Erdheim-Chester disease: from cluster analysis to patient-reported outcomes” finanziato da Erdheim-Chester disease (ECD) Global Alliance nel 2024
-PI del progetto “Epigenome-wide association study in eosinophilic granulomatosis with polyangiitis: understanding disease pathogenesis and response to IL5 blockade.”, finanziato da GSK nel 2023
-PI senior del progetto “Aspetti clinici distintivi del Lupus pediatrico e diagnosi differenziale con le forme monogeniche”, finanziato da “Gruppo LES italiano” 2022
-PI del progetto “Exploring the genetic landscape of Erdheim-Chester disease by integrating GWAS and -omic data” finanziato da Erdheim-Chester disease (ECD) Global Alliance nel 2021
-PI del progetto “FAIRVASC - building registry interoperability to inform clinical care” finanziato da European Joint Programme on Rare Diseases 2019 (EJP-RD)
-PI del progetto “Genome-wide and epigenome-wide association study in patients with Erdheim-Chester disease”, finanziato da Histio UK, 2020
-PI del progetto (Investigator initiated proposal) “Tocilizumab for difficult-to-treat retroperitoneal fibrosis (TOCIRET trial)”, finanziato da Roche, 2015
-PI del progetto “Molecular diagnostics of Erdheim-Chester disease”, finanziato da Cariparma Foundation 2014
-Responsabile di una delle 3 unità partecipanti al progetto “Tailoring Rituximab treatment in ANCA-associated vasculitis: a genetic and immunological approach”, finanziato da Regione Emilia-Romagna
-Progetto “A tailored approach to the immune-monitoring and clinical management of viral and autoimmune diseases”, finanziato da Programma di Ricerca Regione Università 2010-2012
-Co-PI del progetto "Withdrawal of immunosuppression for post-transplantlymphoproliferative disorders (PTLD) and development of tolerance in kidney transplant recipients " finanziato da Cariparma Foundation
-Co-PI del progetto “Etiopathogenesis of idiopatic retroperitoneal fibrosis”, finanziato dal MiUR
-PI del progetto (Investigator Originated Proposal) "Sirolimus plus prednisone for Erdheim-Chester disease. A pilot study", finanziato da Wyeth-Lederle
-Co-PI del progetto “Methotrexate as steroid-sparing agent in idiopathic retroperitoneal fibrosis: a randomised controlled trial”, finanziato da AIFA
RELAZIONI SU INVITO A CONGRESSI INTERNAZIONALI
-2010 (Roma), European Congress of Rheumatology (EULAR) Congress, lecture on “Chronic periaortitis/retroperitoneal fibrosis”
-2011 (Freiburg, Germany), Symposium on ANCA-associated vasculitis organized by Phadia, lecture on “Diagnosis of ANCA-associated vasculitis”
-2011 (Munich, Germany), 39th congress of the German Society of Rheumatology (DGRh), lecture on “Morbus Ormond- Inflammatory aortic aneurysms”
-2012 (Granada, Spain), 8th International Congress on Autoimmunity, lecture on “ANCA and other biomarkers in ANCA-associated vasculitides: a clinician perspective”
-2012 (Génève, Switzerland), Annual Meeting of the Swiss Society of Rheumatology: lectures on “Ormond’s disease” e “IgG4-related diseases”
-2012 (Paris, France): Grand Rounds of the Internal Medicine Dept of the Pitié Salpêtrière Hospital (Chair Pr Zahir Amoura), lecture on “Retroperitoneal Fibrosis”
-2012 (Paris, France): Grand Rounds of the Internal Medicine Dept of the Bichat Hospital (Chair Pr T Papo), lecture on “Retroperitoneal Fibrosis”
-2012 (Roma): 3rd GISEA (Gruppo Italiano di Studio su Early Arthritis) International Meeting “Biomarkers in Rheumatic Diseases”, lecture on “Biomarkers in large-vessel vasculitis”
-2013 (Parma, Italy): International congress “Vasculitis: an update”, lectures on “Hypereosinophilic syndromes and eosinophilic granulomatosis with polyangiitis” and “Update on primary and secondary retroperitoneal fibrosis”
-2013 (Paris): Grand Rounds of the Internal Medicine Department of the Hopital Saint-Louis (chair Pr Alfred Mahr), lecture on “Retroperitoneal Fibrosis”
-2013 (Paris): Séminaire National des DES de Médicine Interne, Journées André Thénot, lecture on “Systemic Idiopathic Fibrosing Diseases”
-2013 (Génève, Switzerland): grand rounds of the Allergy and Immunology Department of the University of Geneva (chair, Pr C. Chizzolini), lecture on “Periaortitis: from retroperitoneal fibrosis to IgG4-related disease”
-2014 (Marseille, France): Journée inter-régionale de formation des DES de médecine interne (chair Pr Nicolas Schleinitz), Université Aix-Marseille, Hôpital de la Conception, lecture on “Chronic periaortitis: from pathogenesis to clinic”
-2014 (Prague, Czech Republic): 5th International Immunology Summit organized by UCB (Chair, Maxime Dougados): lecture on “Managing vasculitis in the clinic”
-2014 (Dublin, Ireland): International course “New Horizons in Rheumatology”, University College Dublin, lecture on “Chronic periaortitis”
-2014 (Paris, France): annual EULAR meeting: lecture on “Chronic periaortitis”
-2015 (London, UK): 17th Vasculitis and ANCA workshop, lecture on “An update on IgG4-related disease”
-2016 (Firenze, Italy): International course “Controversies in Systemic Lupus Erythematosus and Anti-phospholipid syndrome”, lecture on “Renal involvement in Systemic Lupus Erythematosus”
-2016 (Paris, France): lecture on “Renal and Ureteral involvement in Erdheim Chester disease” at the 4th International Erdheim Chester disease symposium
-2017 (Geneva, Switzerland): Grand Rounds of the Internal Medicine and Clinical Immunology Unit, Hopitaux Universitaires Genève (HUG) (chair Prof J Seebach), lecture on “Retroperitoneal fibrosis”
-2017 (Paris, France): National meeting of the French Vasculitis Study Group (chair, Pr L Guillevin): lecture on “Chronic periaortitis and IgG4-related disease”
-2017 (Cambridge, UK): Cambridge Immunology course, lecture on “IgG4-related disease and Erdheim-Chester disease”
-2017 (Vienna, Austria): National meeting of the Austrian Society of Rheumatology, lecture on “Retroperitoneal fibrosis and its overlap with IgG4-related disease”
-2018 (Rochester, MN, USA): 2018 International Conference on Large-Vessel Vasculitis and Related Disorders, Mayo Clinic. lecture on “Chronic periaortitis”
-2018 (Paris, France): XX Journée Pierre Godeau de Immunologie Clinique; lecture on “Aortitis and periaortitis”
-2018 (Fribourg, Switzerland): Grand Round of the Rheumatology Department, Fribourg Hospital (Chair Pr J Dudler): lecture on “IgG4-related disease”
-2018 (Interlaken, Switzerland): Congress of the Société Suisse de Rhumatologie et Société Suisse d’Allergologie et Immunologie, lecture on “Small Vessel Vasculitis: from physiopathology to treatment”
-2018 (Bologna, Italy): 2018 Technologies in endovascular aortic repair (TEAR), lecture on “Aortitis”
-2019 (Lausanne, CHUV, Switzerland): Séminaires de formation continue, lecture on “IgG4-related disease”
-2019 (Seoul, South Korea): 39th National Meeting of the Korean Congress of Rheumatology, Lettura dal titolo “Eosinophilic granulomatosis with polyangiitis”
-2019 (Cambridge, UK): 3rd EUVAS course, Downing College, lectures on “Eosinophilic granulomatosis with polyangiitis” and “IgG4-related disease”
-2019 (Antalya, Turkey): Annual Congress of the Turkish Society of Rheumatology, letcture on “Chronic periaortitis and other inflammatory aortic diseases”
-2019 (Vienna, Austria): Annual Congress of the Austrian Society of Rheumatology, lecture on “Pulmonary-Renal Syndrome”
-2019 (Porto, Portogallo): Porto Autoimmune Disease International Meeting, lecture on “Takayasu arteritis”
-2020 (Grindelwald, Switzerland): Allergy and Immunology Update (AIU) course of the Swiss Society for Allergology and Immunology, lecture on “Periaortitis and the spectrum of IgG4-related diseases”
-2022 (Dublin, Ireland): International vasculitis and ANCA workshop, lecture on Eopsinophilic granulomatosis with Polyangiitis
-2022 (Paris, France): 59th European renal association Congress, lecture on “ANCA-associated kidney vasculitis in childhood”
-2022 (Nantes, France): 84e Congrès de la Societé Nationale Française de Médecine Interne, lecture on “Periaortitis 2022”
-2022 (Lund, Sweden): Nephropathology Course-IgA nephropathy, lecture on”IgAN vs IgAV”
-2022 (Innsbruck, Austria): Nephrology meets Haemato-Oncology, lecture on “Immune check-point inhibitor-induced vasculitis”
-2022 (Firenze, Italy): 4th EUVAS vasculitis course, lectures on “EGPA guidelines”, “IgA vasculitis: towards new therapeutic approaches”, “Periaortitis: IgG4-related or unrelated?”
-2022 (Bruxelles, Belgium): XVI UCLouvain review Course on Systemic Rheumatic Diseases, lecture on “The spectrum of periaortitis and related disorders”
-2022 (Madrid, Spain): 2a Reunión de la Sociedad Española Multidisciplinar de Enfermedades Autoinmunes Sistémicas, lecture on “Erdheim-Chester disease” and “Eosinophilic Granulomatosis with Polyangiitis and the role of biologics”
-2022 (Marseille, France): 85ème Congrès de la SNFMI “Fibrose retro-peritonéale: une maladie associée aux IgG4…ou pas!/ Retroperitoneal fibrosis spectrum in the world of IgG4-related disease”
-2023 (Rochester, USA) Annual Symposium of the Erdheim Chester Disease Global Alliance
Mayo Clinic, Lecture on Genetic aspects of Erdheim Chester disease
-2023 (Zagreb, Croatia) 5th International Conference of the Renal Pathology Society
Lecture on ANCA-associated vasculitis and other rare vasculitides in children
-2023 (Florence, Italy) 5th meeting of the European EGPA study group, lecture “Pathogenesis of EGPA"
-2023 (Paris, France): MaRIH (Maladies Rares immune-hematologiques), lecture on “The genetic landscape of Erdheim-Chester disease”
-2024 (Philadelphia) Lecture on “European EGPA study group” at the Vasculitis Clinical Research Consortium meeting
-2024 (Online) Canadian Vasculitis webinar series, lecture on “EGPA guidelines”
-2024 (Online) Johns Hopkins University, Baltimore, Grand Round lecture on “IgG4-related disease”
-2024 (Online) Royal Society of Medicine webinar series, lecture on “EGPA”
-2024 (Istanbul, Turkey) EUVAS course, lecture on “IgG4-related disease: not just a matter of IgG4”
-2024 (Lausanne, Switzerland) Annual Meeting of the Swiss Society of Rheumatology, lecture on “IgG4-related diseases”
-2024 (Goteborg, Sweden) Annual Meeting of the Pediatric Rheumatology European Society (PReS), lecture entitled “Genome-wide association studies in vasculitis”
-2024 (Graz, Austria) EUVAS course (satellite to the Austrian Nephrology Society meeting), lecture on “IgA vasculitis”
-2024 (Genova, Italy) International meeting “Podocytopathies and lupus nephritis”, lecture on “DNASE mutations, significance and therapy”
-2025 (Firenze, Italy) Florence Multidisciplinary Expert Meeting on Renal Cell Carcinoma, lecture entitled “Nephrological assessment before and after treatment for RCC”
-2025 (Prague, Czech Republic), international meeting “Rheumatology Update Europe”, lecture entitled “Retroperitoneal fibrosis and IgG4-related disease”
-2025 (Riyadh, Saudi Arabia), EUVAS Middle East course, lectures entitled “Pathophysiology of EGPA”, “IgA Vasculitis”, IgG4-related disease”
-2025 (online) ERN RITA and EUVAS webinar, lecture entitled “IgA vasculitis in adults”
ALTRI APPUNTAMENTI
-Esperto esterno per il Comitato per i Medicinali Orfani di European Medicines Agency (EMA)
-Segretario dI “European Vasculitis Genetics Consortium”
-Membro del gruppo di lavoro sull’Eosinophilic Granulomatosis with Polyangiitis (EGPA)
-Membro del comitato consultivo della Erdheim Chester Disease Global Alliance
-Membro del comitato ERA-EDTA e EULAR per le raccomandazioni sulle vasculiti ANCA-associate
-Co-presidente del European EGPA Study Group
-Revisore per l’HDR (Habilitation à Diriger la Recherche), Université Pierre et Marie Curie (Sorbonne Universités), Parigi
-Revisore per il Ministero della Salute francese
-Esaminatore esterno per tesi di dottorato presso University of Cambridge (Regno Unito), University of Granada (Spagna), University of Leiden (Paesi Bassi)
La sua attività di ricerca si incentra sullo studio delle malattie rare immuno-mediate con coinvolgimento renale quali le vasculiti ed il lupus eritematoso sistemico, le malattie fibro-infiammatorie come la malattia IgG4-correlata, e l’istiocitosi di Erdheim-Chester.
Legenda
Augusto Vaglio graduated in Medicine and Surgery in 2000 from the University of Parma. At the same university, he completed his specialization in Nephrology in 2005 and subsequently earned a PhD in Pathophysiology of Renal Failure in 2009.
During his training, he conducted research at the international level: he was a post-doctoral fellow at Emory University in Atlanta, USA, and a visiting fellow at the University of Cambridge, United Kingdom.
He is currently an Associate Professor of Nephrology at the University of Florence and Director of the School of Specialization in Nephrology at the same university. He carries out his clinical work at the Nephrology Unit of the Meyer IRCCS University Hospital in Florence.
EDUCATION
-Scientific Liceo ”A. Vallone” Galatina (LE) (final mark 60/60) (1988-1993)
-Medical School, University of Parma Italy (final mark 110/110 magna cum laude) (1994-2000)
-Post-graduate School of Nephrology (final mark 50/50 magna cum laude), University of Parma, Italy (2000-2005)
-Post-doctoral fellowship, Lowance Center for Human Immunology, Emory University, Atlanta, USA (2005-2006)
-PhD in Nephrology, University of Parma, Italy (2006-2009)
TEACHING
-Professor at the Post-Graduate Nephrology School, Parma University (2005-2018)
-Adjunct Professor, Parma University School of Medicine (2012-2018)
-Professor at the PhD program in Health Sciences, Medical School, Parma University (2013-date)
-Visiting Professor, Department of Medicine, University of Cambridge, UK (June-July 2017)
-Associate Professor of Nephrology, University of Firenze 2018-date)
-Director, Post-graduate fellowship program in nephrology, University of Firenze (2019-date)
CURRENT POSITION
-Associate Professor of Nephrology, University of Firenze, and Consultant Nephrologist, Meyer Children’s Hospital IRCCS, Firenze
-Director of the Post-Graduate Fellowship Program in Nephrology, University of Firenze
RESEARCH AREAS
-ANCA-associated vasculitis
-Retroperitoneal fibrosis and IgG4-related disease
-Erdheim-Chester disease
-Systemic lupus erythematosus
BIBLIOMETRIC DATA
-286 articles published in international, English-language, peer-reviewed journals
-First or last author in 145/286 articles
-Citations: 14037 (Scopus)
GRANTS
-Senior PI of the project “A new comprehensive approach to predict long-term prognosis in Erdheim-Chester disease: from cluster analysis to patient-reported outcomes” funded by Erdheim-Chester disease (ECD) Global Alliance in 2024
-PI of the project “Epigenome-wide association study in eosinophilic granulomatosis with polyangiitis: understanding disease pathogenesis and response to IL5 blockade.”, funded by GSK in 2023
-Senior investigator of the project “Aspetti clinici distintivi del Lupus pediatrico e diagnosi differenziale con le forme monogeniche”, funded by “Gruppo LES italiano” 2022
-PI of the project entitled “Exploring the genetic landscape of Erdheim-Chester disease by integrating GWAS and -omic data” funded by the Erdheim-Chester disease (ECD) Global Alliance in 2021
-PI of the project “FAIRVASC - building registry interoperability to inform clinical care” funded by the European Joint Programme on Rare Diseases 2019 (EJP-RD)
-PI of the project “Genome-wide and epigenome-wide association study in patients with Erdheim-Chester disease”, funded by Histio UK, 2020
-PI of the project (Investigator initiated proposal) “Tocilizumab for difficult-to-treat retroperitoneal fibrosis (TOCIRET trial)”, funded by Roche, 2015
-PI of the project “Molecular diagnostics of Erdheim-Chester disease”, funded by Cariparma Foundation 2014
-Leader of one of the 3 participating units of the project “Tailoring Rituximab treatment in ANCA-associated vasculitis: a genetic and immunological approach”, funded by Regione Emilia-Romagna
-Workpackage leader of the project “A tailored approach to the immune-monitoring and clinical management of viral and autoimmune diseases”, funded by Programma di Ricerca Regione Università 2010-2012
-Co-PI of the project "Withdrawal of immunosuppression for post-transplantlymphoproliferative disorders (PTLD) and development of tolerance in kidney transplant recipients " funded by Cariparma Foundation
-Co-PI of the project “Etiopathogenesis of idiopatic retroperitoneal fibrosis”, funded by the ministry of University and Research (MiUR)
-PI of the Project (Investigator Originated Proposal) "Sirolimus plus prednisone for Erdheim-Chester disease. A pilot study", funded by Wyeth-Lederle
-Co-PI of the project “Methotrexate as steroid-sparing agent in idiopathic retroperitoneal fibrosis: a randomised controlled trial”, funded by AIFA
INVITED LECTURES IN INTERNATIONAL MEETINGS
OTHER APPOINTMENTS
-External expert for the European Medicines Agency (EMA) Committee for Orphan Medicinal Products
-Secretary of the European Vasculitis Genetics Consortium
-Member of the Eosinophilic Granulomatosis with Polyangiitis Task Force
-Member of the advisory board of the Erdheim Chester Disease Global Alliance
-Member of the ERA-EDTA and EULAR committee for the Recommendations on ANCA-associated vasculitis
-Co-president of the European EGPA Study Group
-Reviewer for HDR (Habilitation à Diriger la Recherche), Université Pierre et Marie Curie (Sorbonne Universités), Paris
-Reviewer for the French Ministry of Health
-External examiner for PhD theses University of Cambridge, UK; University of Granada, Spain; Uniiversity of Leiden, the Netherlands
His research focuses on the study of rare immune-mediated diseases with renal involvement, such as vasculitis and systemic lupus erythematosus, fibro-inflammatory diseases such as IgG4-related disease, and Erdheim-Chester disease.
