Personale

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Italiano

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English

Curriculum

Francesco DE LOGU

Ruolo attuale:: Ricercatore Legge 240/10 a tempo determinato
SSD:: BIOS-11/A - Farmacologia
Afferenza organizzativa:: Dipartimento di Scienze della Salute (DSS)

Recapiti

	0552758134
	francesco.delogu(AT)unifi.it

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PSICOFARMACOLOGIA - La lezione del giorno 13/03/2025 non si terrà

PSICOFARMACOLOGIA - La lezione del giorno 13/03/2025 (per motivi di salute) sarà recuperata in data 20/03/2025 con solito orario 15.30-18.30

Francesco DE LOGU

Pubblicazioni

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Tesi di Dottorato

Livio Tarchi, Gaia Maiolini, Gianluca Villa, Paolo Rovero, Francesco De Logu, Romina Nassini, Rachele Garella, Chiara Sassoli, Valdo Ricca, Giovanni Castellini, Roberta Squecco (2025). The hormetic potential of GDF15 in skeletal muscle health and regeneration: a comprehensive systematic review. CURRENT MOLECULAR MEDICINE, pp. 0-0, ISSN:1566-5240

Brum, Evelyne Silva; Fialho, Maria Fernanda Pessano; Souza Monteiro de Araújo, Daniel; Landini, Lorenzo; Marini, Matilde; Titiz, Mustafa; Kuhn, Bruna Luiza; Frizzo, Clarissa Piccinin; Araújo, Pedro Henrique Silva; Guimarães, Rafaela Mano; Cunha, Thiago Mattar; Silva, Cássia Regina; Trevisan, Gabriela; Geppetti, Pierangelo; Nassini, Romina; De Logu, Francesco; Oliveira, Sara Marchesan (2024). Schwann cell TRPA1 elicits reserpine‐induced fibromyalgia pain in mice. BRITISH JOURNAL OF PHARMACOLOGY, vol. 181, pp. 3445-3461, ISSN:0007-1188 DOI

Bellantoni, Elisa; Marini, Matilde; Chieca, Martina; Gabellini, Chiara; Crapanzano, Erica Lucia; Souza Monteiro de Araujo, Daniel; Nosi, Daniele; Roschi, Lorenzo; Landini, Lorenzo; De Siena, Gaetano; Pensieri, Pasquale; Mastricci, Alessandra; Scuffi, Irene; Geppetti, Pierangelo; Nassini, Romina; De Logu, Francesco (2024). Schwann cell transient receptor potential ankyrin 1 (TRPA1) ortholog in zebrafish larvae mediates chemotherapy‐induced peripheral neuropathy. BRITISH JOURNAL OF PHARMACOLOGY, vol. 181, pp. 4859-4873, ISSN:0007-1188 DOI

Titiz, Mustafa; Landini, Lorenzo; Souza Monteiro de Araujo, Daniel; Marini, Matilde; Seravalli, Viola; Chieca, Martina; Pensieri, Pasquale; Montini, Marco; De Siena, Gaetano; Pasquini, Benedetta; Vannuccini, Silvia; Iannone, Luigi Francesco; Cunha, Thiago M.; Brancolini, Giulia; Bellantoni, Elisa; Scuffi, Irene; Mastricci, Alessandra; Tesi, Martina; Di Tommaso, Mariarosaria; Petraglia, Felice; Geppetti, Pierangelo; Nassini, Romina; De Logu, Francesco (2024). Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis. NATURE COMMUNICATIONS, vol. 15, pp. 0-0, ISSN:2041-1723 DOI

Nozzoli, Filippo; Catalano, Martina; Messerini, Luca; Cianchi, Fabio; Nassini, Romina; De Logu, Francesco; Iannone, Luigi Francesco; Ugolini, Filippo; Simi, Sara; Massi, Daniela; Geppetti, Pierangelo; Roviello, Giandomenico (2024). Perineural invasion score system and clinical outcomes in resected pancreatic cancer patients. PANCREATOLOGY, vol. -, pp. 1-9, ISSN:1424-3903 DOI

Latini, Laura; De Araujo, Daniel Souza Monteiro; Amato, Rosario; Canovai, Alessio; Buccarello, Lucia; De Logu, Francesco; Novelli, Elena; Vlasiuk, Anastasiia; Malerba, Francesca; Arisi, Ivan; Florio, Rita; Asari, Hiroki; Capsoni, Simona; Strettoi, Enrica; Villetti, Gino; Imbimbo, Bruno Pietro; Dal Monte, Massimo; Nassini, Romina; Geppetti, Pierangelo; Marinelli, Silvia; Cattaneo, Antonino (2024). A p75 neurotrophin receptor‐sparing nerve growth factor protects retinal ganglion cells from neurodegeneration by targeting microglia. BRITISH JOURNAL OF PHARMACOLOGY, vol. 181, pp. 4890-4919, ISSN:0007-1188 DOI

Nozzoli, Filippo; Nassini, Romina; De Logu, Francesco; Catalano, Martina; Roviello, Giandomenico; Massi, Daniela (2024). Reconceiving Perineural Invasion in Cutaneous Squamous Cell Carcinoma: From Biological to Histopathological Assessment. PATHOBIOLOGY, vol. -, pp. 1-13, ISSN:1015-2008 DOI

Cherchi, Federica; Venturini, Martina; Magni, Giada; Frulloni, Lucia; Chieca, Martina; Buonvicino, Daniela; Santalmasi, Clara; Rossi, Francesca; De Logu, Francesco; Coppi, Elisabetta; Pugliese, Anna Maria (2024). Adenosine A2B receptors differently modulate oligodendrogliogenesis and myelination depending on their cellular localization. GLIA, vol. 72, pp. 1985-2000, ISSN:1098-1136 DOI

Mattei, Gianluca; Baragli, Marta; Gega, Barbara; Mingrino, Alessandra; Chieca, Martina; Ducci, Tommaso; Frigè, Gianmaria; Mazzarella, Luca; D'Aurizio, Romina; De Logu, Francesco; Nassini, Romina; Pelicci, Pier Giuseppe; Magi, Alberto (2024). PoreMeth2: decoding the evolution of methylome alterations with Nanopore sequencing. DOI

Nascimento, Thaianne Hanah Oliveira do; Pereira-Figueiredo, Danniel; Veroneze, Louise; Nascimento, Amanda Alves; De Logu, Francesco; Nassini, Romina; Campello-Costa, Paula; Faria-Melibeu, Adriana da Cunha; Souza Monteiro de Araújo, Daniel; Calaza, Karin Costa (2024). Functions of TRPs in retinal tissue in physiological and pathological conditions. FRONTIERS IN MOLECULAR NEUROSCIENCE, vol. 17, pp. 0-0, ISSN:1662-5099 DOI

Catalano, Martina; Nozzoli, Filippo; De Logu, Francesco; Nassini, Romina; Roviello, Giandomenico (2024). Management Approaches for High-Risk Cutaneous Squamous Cell Carcinoma with Perineural Invasion: An Updated Review. CURRENT TREATMENT OPTIONS IN ONCOLOGY, vol. -, pp. 1-9, ISSN:1527-2729 DOI

Landini, Lorenzo; Souza Monteiro de Araujo, Daniel; Chieca, Martina; De Siena, Gaetano; Bellantoni, Elisa; Geppetti, Pierangelo; Nassini, Romina; De Logu, Francesco (2023). Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine. JOURNAL OF BIOMEDICAL SCIENCE, vol. 30, pp. 28-34, ISSN:1423-0127 DOI

Marini, Matilde; Titiz, Mustafa; Souza Monteiro de Araújo, Daniel; Geppetti, Pierangelo; Nassini, Romina; De Logu, Francesco (2023). TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches. BIOMOLECULES, vol. 13, pp. 0-0, ISSN:2218-273X DOI

Dalenogare, Diéssica Padilha; Souza Monteiro de Araújo, Daniel; Landini, Lorenzo; Titiz, Mustafa; De Siena, Gaetano; De Logu, Francesco; Geppetti, Pierangelo; Nassini, Romina; Trevisan, Gabriela (2023). Neuropathic-like Nociception and Spinal Cord Neuroinflammation Are Dependent on the TRPA1 Channel in Multiple Sclerosis Models in Mice. CELLS, vol. 12, pp. 0-0, ISSN:2073-4409 DOI

Landini, Lorenzo; Marini, Matilde; Souza Monteiro de Araujo, Daniel; Romitelli, Antonia; Montini, Marco; Albanese, Valentina; Titiz, Mustafa; Innocenti, Alessandro; Bianchini, Francesca; Geppetti, Pierangelo; Nassini, Romina; De Logu, Francesco (2023). Schwann cell insulin-like growth factor receptor type-1 mediates metastatic bone cancer pain in mice. BRAIN, BEHAVIOR, AND IMMUNITY, vol. 110, pp. 348-364, ISSN:1090-2139 DOI

De Logu, Francesco; De Siena, Gaetano; Landini, Lorenzo; Marini, Matilde; Souza Monteiro de Araujo, Daniel; Albanese, Valentina; Preti, Delia; Romitelli, Antonia; Chieca, Martina; Titiz, Mustafa; Iannone, Luigi F; Geppetti, Pierangelo; Nassini, Romina (2023). Non-neuronal TRPA1 encodes mechanical allodynia associated with neurogenic inflammation and partial nerve injury in rats. BRITISH JOURNAL OF PHARMACOLOGY, vol. 180, pp. 1232-1246, ISSN:1476-5381 DOI

De Logu, Francesco; Ugolini, Filippo; Iannone, Luigi Francesco; Simi, Sara; Maio, Vincenza; de Giorgi, Vincenzo; Maria di Giacomo, Anna; Miracco, Clelia; Cossu, Antonio; Palmieri, Giuseppe; Mandalà, Mario; Massi, Daniela (2023). Spatial Proximity and Relative Distribution of Tumor-Infiltrating Lymphocytes and Macrophages Predict Survival in Melanoma. LABORATORY INVESTIGATION, vol. 103, pp. 0-0, ISSN:0023-6837 DOI

Ugolini, Filippo; De Logu, Francesco; Iannone, Luigi Francesco; Brutti, Francesca; Simi, Sara; Maio, Vincenza; de Giorgi, Vincenzo; Maria di Giacomo, Anna; Miracco, Clelia; Federico, Francesco; Peris, Ketty; Palmieri, Giuseppe; Cossu, Antonio; Mandalà, Mario; Massi, Daniela; Laurino, Marco (2023). Tumor-Infiltrating Lymphocyte Recognition in Primary Melanoma by Deep Learning Convolutional Neural Network. THE AMERICAN JOURNAL OF PATHOLOGY, pp. 0-0, ISSN:0002-9440 DOI

Souza Monteiro de Araújo, Daniel; Brito, Rafael; Pereira-Figueiredo, Danniel; Dos Santos-Rodrigues, Alexandre; De Logu, Francesco; Nassini, Romina; Zin, Andrea; Calaza, Karin C (2022). Retinal Toxicity Induced by Chemical Agents. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, pp. 8182-8210, ISSN:1422-0067 DOI

Audrito V., Moiso E., Ugolini F., Messana V.G., Brandimarte L., Manfredonia I., Bianchi S., De Logu F., Nassini R., Szumera-Ciećkiewicz A., Taverna D., Massi D. (2022). Tumors carrying BRAF-mutations over-express NAMPT that is genetically amplified and possesses oncogenic properties. JOURNAL OF TRANSLATIONAL MEDICINE, pp. 0-0, ISSN:1479-5876 DOI

De Logu, Francesco; Maglie, Roberto; Titiz, Mustafa; Poli, Giulio; Landini, Lorenzo; Marini, Matilde; Monteiro de Araujo, Daniel Souza; De Siena, Gaetano; Montini, Marco; Cabrini, Daniela Almeida; Otuki, Michel Fleith; Pawloski, Priscila Lúcia; Antiga, Emiliano; Tuccinardi, Tiziano; Calixto, João Batista; Geppetti, Pierangelo; Nassini, Romina; André, Eunice (2022). miRNA-203b-3p induces acute and chronic pruritus via 5-HTR2B and TRPV4. JOURNAL OF INVESTIGATIVE DERMATOLOGY, pp. 0-0, ISSN:0022-202X DOI

Ugolini, Filippo; Baroni, Gianna; Nassini, Romina; De Logu, Francesco; Massi, Daniela (2022). A Fast and Automated Melanin-bleaching Method for Histopathologic Evaluation of Pigmented Melanoma Tissues. APPLIED IMMUNOHISTOCHEMISTRY AND MOLECULAR MORPHOLOGY, vol. 30, pp. 311-316, ISSN:1541-2016 DOI

Maglie R.; Ugolini F.; De Logu F.; Nassini R.; Simi S.; Nardiello P.; Pasqualini E.; Baroni G.; Del Bianco E.; Massi D.; Antiga E. (2022). Overexpression of helper T cell type 2-related molecules in the skin of patients with eosinophilic dermatosis of hematologic malignancy. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, pp. .-., ISSN:0190-9622 DOI

Iannone L.F.; Nassini R.; Patacchini R.; Geppetti P.; De Logu F. (2022). Neuronal and non-neuronal TRPA1 as therapeutic targets for pain and headache relief. TEMPERATURE, pp. 1-17, ISSN:2332-8940 DOI

Iannone L.F.; De Logu F.; Geppetti P.; De Cesaris F. (2022). The role of TRP ion channels in migraine and headache. NEUROSCIENCE LETTERS, vol. 768, pp. 0-0, ISSN:0304-3940 DOI

Hurdogan, Ozge; De Logu, Francesco; Galli, Francesca; Tuncer, Samuray; Ugolini, Filippo; Simi, Sara; Portelli, Francesca; Nassini, Romina; Massi, Daniela; Buyukbabani, Nesimi (2022). Digital Quantification of Intratumoral CD8+ T-Cells Predicts Relapse and Unfavorable Outcome in Uveal Melanoma. CANCERS, vol. 14, pp. 0-0, ISSN:2072-6694 DOI

De Logu F.; Nassini R.; Hegron A.; Landini L.; Jensen D.D.; Latorre R.; Ding J.; Marini M.; Souza Monteiro de Araujo D.; Ramirez-Garcia P.; Whittaker M.; Retamal J.; Titiz M.; Innocenti A.; Davis T.P.; Veldhuis N.; Schmidt B.L.; Bunnett N.W.; Geppetti P. (2022). Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice. NATURE COMMUNICATIONS, vol. 13, pp. 0-0, ISSN:2041-1723 DOI

Nozzoli, Filippo; Lazar, Alexander J; Castiglione, Francesca; Campanacci, Domenico Andrea; Beltrami, Giovanni; De Logu, Francesco; Caporalini, Chiara; Massi, Daniela; Roviello, Giandomenico (2022). NTRK Fusions Detection in Paediatric Sarcomas to Expand the Morphological Spectrum and Clinical Relevance of Selected Entities. PATHOLOGY AND ONCOLOGY RESEARCH, vol. 28, pp. 0-0, ISSN:1532-2807 DOI

Dalenogare D.P.; Ritter C.; Bellinaso F.R.A.; Kudsi S.Q.; Pereira G.C.; Fialho M.F.P.; Luckemeyer D.D.; Antoniazzi C.T.D.; Landini L.; Ferreira J.; Bochi G.V.; Oliveira S.M.; De Logu F.; Nassini R.; Geppetti P.; Trevisan G. (2021). Periorbital nociception in a progressive multiple sclerosis mouse model is dependent on trpa1 channel activation. PHARMACEUTICALS, vol. 14, pp. 0-0, ISSN:1424-8247 DOI

de Logu F.; Marini M.; Landini L.; de Araujo D.S.M.; Bartalucci N.; Trevisan G.; Bruno G.; Marangoni M.; Schmidt B.L.; Bunnett N.W.; Geppetti P.; Nassini R. (2021). Peripheral nerve resident macrophages and schwann cells mediate cancer-induced pain A C. CANCER RESEARCH, vol. 81, pp. 3387-3401, ISSN:0008-5472 DOI

De Logu F.; Boccella S.; Guida F. (2021). Editorial: The Role of Neuroinflammation in Chronic Pain Development and Maintenance. FRONTIERS IN PHARMACOLOGY, vol. 12, pp. 0-0, ISSN:1663-9812 DOI

De Logu F.; de Araujo D.S.M.; Ugolini F.; Iannone L.F.; Vannucchi M.; Portelli F.; Landini L.; Titiz M.; De Giorgi V.; Geppetti P.; Massi D.; Nassini R. (2021). The trpa1 channel amplifies the oxidative stress signal in melanoma. CELLS, vol. 10, pp. 0-0, ISSN:2073-4409 DOI

Bruno G.; De Logu F.; Souza Monteiro de Araujo D.; Subbiani A.; Lunardi F.; Rettori S.; Nassini R.; Favre C.; Calvani M. (2021). β2-and β3-Adrenergic Receptors Contribute to Cancer-Evoked Pain in a Mouse Model of Osteosarcoma via Modulation of Neural Macrophages. FRONTIERS IN PHARMACOLOGY, vol. 12, pp. 0-0, ISSN:1663-9812 DOI

Maglie R.; de Araujo D.S.M.; Antiga E.; Geppetti P.; Nassini R.; De Logu F. (2021). The role of trpa1 in skin physiology and pathology. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, pp. 1-13, ISSN:1661-6596 DOI

Maglie R.; Ugolini F.; De Logu F.; Simi S.; Senatore S.; Montefusco F.; Nassini R.; Massi D.; Antiga E. (2021). Dupilumab for the treatment of recalcitrant eosinophilic dermatosis of haematologic malignancy. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, vol. 35, pp. e501-e503, ISSN:0926-9959 DOI

Dalenogare, Diéssica P; Theisen, Maria C; Peres, Diulle S; Fialho, Maria F P; Andrighetto, Nathaly; Barros, Laura; Landini, Lorenzo; Titiz, Mustafa; De Logu, Francesco; Oliveira, Sara M; Geppetti, Pierangelo; Nassini, Romina; Trevisan, Gabriela (2021). Transient receptor potential ankyrin 1 mediates headache-related cephalic allodynia in a mouse model of relapsing-remitting multiple sclerosis. PAIN, vol. Publish Ahead of Print, pp. 0-0, ISSN:0304-3959 DOI

De Logu F.; Galli F.; Nassini R.; Ugolini F.; Simi S.; Cossa M.; Miracco C.; Gianatti A.; De Giorgi V.; Rulli E.; Cossu A.; Massi D.; Mandala M. (2021). Digital immunophenotyping predicts disease free and overall survival in early stage melanoma patients. CELLS, vol. 10, pp. 1-20, ISSN:2073-4409 DOI

Novelli D.; Fumagalli F.; Staszewsky L.; Ristagno G.; Olivari D.; Masson S.; De Giorgio D.; Ceriani S.; Massafra R.; De Logu F.; Nassini R.; Milioli M.; Facchinetti F.; Cantoni S.; Trevisani M.; Letizia T.; Russo I.; Salio M.; Latini R. (2020). Primary pulmonary arterial hypertension: Protocol to assess comprehensively in the rat the response to pharmacologic treatments. METHODSX (AMSTERDAM), vol. 7, pp. 100771-100771, ISSN:2215-0161 DOI

Calvani M.; Bruno G.; Dabraio A.; Subbiani A.; Bianchini F.; Fontani F.; Casazza G.; Vignoli M.; De Logu F.; Frenos S.; Filippi L.; Favre C. (2020). β3-Adrenoreceptor Blockade Induces Stem Cells Differentiation in Melanoma Microenvironment. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 21, pp. 0-0, ISSN:1661-6596 DOI

1. Jain P., Materazzi S., De Logu F., Rossi Degl’Innocenti D., Fusi C., Li Puma S., Marone I. M., Coppi E., Holzer P., Geppetti P., and Nassini R. (2020). Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis. SCIENTIFIC REPORTS, pp. 0-0, ISSN:2045-2322 DOI

Szumera-Cieckiewicz A.; Bosisio F.; Teterycz P.; Antoranz A.; De Logu F.; Koljenovic S.; van de Wiel B.A.; Blokx W.; van Kempen L.C.; Rutkowski P.; Christopher van Akkooi A.; Cook M.; Massi D. (2020). SOX10 is as specific as S100 protein in detecting metastases of melanoma in lymph nodes and is recommended for sentinel lymph node assessment. EUROPEAN JOURNAL OF CANCER, vol. 137, pp. 175-182, ISSN:0959-8049 DOI

Francesco De Logu, Filippo Ugolini, Vincenza Maio, Sara Simi, Antonio Cossu, Daniela Massi, Italian Association for Cancer Research (AIRC) Study Group, Romina Nassini, Marco Laurino (2020). Recognition of Cutaneous Melanoma on Digitized Histopathological Slides via Artificial Intelligence Algorithm. FRONTIERS IN ONCOLOGY, pp. 0-0, ISSN:2234-943X DOI

Roviello G.; D'Angelo A.; Sciortino M.; Mini E.; Nobili S.; De Logu F.; Massi D. (2020). TRK fusion positive cancers: From first clinical data of a TRK inhibitor to future directions. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, vol. 152, pp. 0-0, ISSN:1040-8428 DOI

Souza Monteiro de Araujo D.; Nassini R.; Geppetti P.; De Logu F. (2020). TRPA1 as a therapeutic target for nociceptive pain. EXPERT OPINION ON THERAPEUTIC TARGETS, pp. 1-12-12, ISSN:1472-8222 DOI

Souza Monteiro de Araujo D.; De Logu F.; Adembri C.; Rizzo S.; Janal M.N.; Landini L.; Magi A.; Mattei G.; Cini N.; Pandolfo P.; Geppetti P.; Nassini R.; Calaza K.C. (2020). TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice. CELL DEATH & DISEASE, vol. 11, pp. 0-0, ISSN:2041-4889 DOI

De Logu F.; Trevisan G.; Marone I.M.; Coppi E.; Padilha Dalenogare D.; Titiz M.; Marini M.; Landini L.; Souza Monteiro de Araujo D.; Li Puma S.; Materazzi S.; De Siena G.; Geppetti P.; Nassini R. (2020). Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4. BMC BIOLOGY, vol. 18, pp. 197-197, ISSN:1741-7007 DOI

de Logu, Francesco; Dal-Toé De Prá, Samira; Tatiane de David Antoniazzi, Caren; Qader Kudsi, Sabrina; Ronsani Ferro, Paula; Landini, Lorenzo; Karine Rigo, Flávia; de Bem Silveira, Gustavo; Cesar Lock Silveira, Paulo; Marchesan Oliveira, Sara; Marini, Matilde; Mattei, Gianluca; Ferreira, Juliano; Geppetti, Pierangelo; Nassini, Romina; Trevisan, Gabriela (2020). Macrophages and Schwann cell TRPA1 mediate chronic allodynia in a mouse model of complex regional pain syndrome type I. BRAIN BEHAVIOR AND IMMUNITY, pp. ---, ISSN:0889-1591 DOI

De Logu F.; Ugolini F.; Caporalini C.; Palomba A.; Simi S.; Portelli F.; Campanacci D.A.; Beltrami G.; Massi D.; Nassini R. (2020). Trpa1 expression in synovial sarcoma may support neural origin. BIOMOLECULES, vol. 10, pp. 1-13, ISSN:2218-273X DOI

Vanni I., Casula M., Pastorino L., Manca A., Dalmasso B., Andreotti V., Pisano M., Colombino M., Covre A., Di Giacomo A.M., Maio M., De Logu F., Massi D., Portelli F., Anichini A., Mortarini R., Bruno W., Cabiddu F., Spagnolo F., Palomba G., Sini M.C., Fedeli M.A., Lissia A., Pfeffer U., Tanda E.T., Rozzo C., Paliogiannis P., Cossu A., Ghiorzo P., Palmieri G., Caracò C., Grimaldi A.M., Ferraresi V., Mandalà M., Patuzzo R., Quaglino P., Queirolo P., Stanganelli I. (2020). Quality assessment of a clinical next-generation sequencing melanoma panel within the Italian Melanoma Intergroup (IMI). DIAGNOSTIC PATHOLOGY, vol. 15, pp. 143-145, ISSN:1746-1596 DOI

Massi D.; Rulli E.; Cossa M.; Valeri B.; Rodolfo M.; Merelli B.; De Logu F.; Nassini R.; Del Vecchio M.; Di Guardo L.; De Penni R.; Guida M.; Sileni V.C.; Di Giacomo A.M.; Tucci M.; Occelli M.; Portelli F.; Vallacchi V.; Consoli F.; Quaglino P.; Queirolo P.; Baroni G.; Carnevale-Schianca F.; Cattaneo L.; Minisini A.; Palmieri G.; Rivoltini L.; Mandala M.; Simi S.; Galli F. (2019). The density and spatial tissue distribution of CD8+ and CD163+ immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors. JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 7, pp. 308-308, ISSN:2051-1426 DOI

De Logu F.; Geppetti P. (2019). Ion channel pharmacology for pain modulation. In: James E. Barrett, Clive P. Page, Martin C. Michel. Handbook of Experimental Pharmacology, pp. 161-186 Springer, ISBN:978-3-030-35361-2. DOI

Francesco De Logu (2019). Caratterizzazione del ruolo fisiopatologico e funzionale del canali Transient Receptor Potential (TRP) nelle patologie dolorose di origine infiammatoria e neuropatica. (Tutor: Pierangelo Geppetti)

Li Puma S.; Landini L.; Macedo S.J.; Seravalli V.; Marone I.M.; Coppi E.; Patacchini R.; Geppetti P.; Materazzi S.; Nassini R.; De Logu F. (2019). TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 23, pp. 1976-1986, ISSN:1582-1838 DOI Accesso ONLINE all'editore

De Logu F.; Landini L.; Janal M.N.; Li Puma S.; De Cesaris F.; Geppetti P.; Nassini R. (2019). Migraine-provoking substances evoke periorbital allodynia in mice. THE JOURNAL OF HEADACHE AND PAIN, vol. 20, pp. 18-18, ISSN:1129-2369 DOI Accesso ONLINE all'editore

Noroes M.M.; Santos L.G.; Gavioli E.C.; de Paula Soares Rachetti V.; Otuki M.F.; de Almeida Cabrini D.; da Silveira Prudente A.; Oliveira J.R.J.M.; de Carvalho Goncalves M.; Ferreira J.; Preti D.; De Logu F.; Nassini R.; Andre E. (2019). Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 858, pp. 172460--, ISSN:0014-2999 DOI Accesso ONLINE all'editore

De Logu F.; Li Puma S.; Landini L.; Tuccinardi T.; Poli G.; Preti D.; De Siena G.; Patacchini R.; Tsagareli M.G.; Geppetti P.; Nassini R. (2019). The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel. PHARMACOLOGICAL RESEARCH, vol. 142, pp. 127-139, ISSN:1043-6618 DOI Accesso ONLINE all'editore

Cantoni S.; Cavalli S.; Pastore F.; Accetta A.; Pala D.; Vaccaro F.; Cesari N.; De Logu F.; Nassini R.; Villetti G.; Facchinetti F. (2019). Pharmacological characterization of a highly selective Rho kinase (ROCK) inhibitor and its therapeutic effects in experimental pulmonary hypertension. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 850, pp. 126-134, ISSN:0014-2999 DOI Accesso ONLINE all'editore

Brusco, Indiara; Li Puma, Simone; Chiepe, Kelly Braga; da Silva Brum, Evelyne; de David Antoniazzi, Caren Tatiane; de Almeida, Amanda Spring; Camponogara, Camila; Silva, Cássia Regina; De Logu, Francesco; de Andrade, Vanessa Moraes; Ferreira, Juliano; Geppetti, Pierangelo; Nassini, Romina; Oliveira, Sara Marchesan; Trevisan, Gabriela (2019). Dacarbazine alone or associated with melanoma-bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice. INTERNATIONAL JOURNAL OF CANCER, pp. 0-0, ISSN:0020-7136 DOI

Calvani, Maura; Bruno, Gennaro; Dal Monte, Massimo; Nassini, Romina; Fontani, Filippo; Casini, Arianna; Cavallini, Lorenzo; Becatti, Matteo; Bianchini, Francesca; De Logu, Francesco; Forni, Giulia; la Marca, Giancarlo; Calorini, Lido; Bagnoli, Paola; Chiarugi, Paola; Pupi, Alberto; Azzari, Chiara; Geppetti, Pierangelo; Favre, Claudio; Filippi, Luca (2019). β3-adrenoceptor as a potential immuno-suppressor agent in melanoma. BRITISH JOURNAL OF PHARMACOLOGY, vol. 176, pp. 2509-2524, ISSN:1476-5381 DOI

De Logu, Francesco; Li Puma, Simone; Landini, Lorenzo; Portelli, Francesca; Innocenti, Alessandro; de Araújo, Daniel Souza Monteiro; Janal, Malvin N; Patacchini, Riccardo; Bunnett, Nigel W; Geppetti, Pierangelo; Nassini, Romina (2019). Schwann cells expressing nociceptive channel TRPA1 orchestrate ethanol-evoked neuropathic pain in mice. THE JOURNAL OF CLINICAL INVESTIGATION, pp. 128022-128022, ISSN:1558-8238 DOI

De Logu F, Nassini R, Landini L, Geppetti P (2019). Pathways of CGRP Release from Primary Sensory Neurons.. In: De Logu, F., Nassini, R., Landini, L. and Geppetti, P.. Handbook of Experimental Pharmacology, pp. 65-84 Springer, Cham.

Novelli D.; Fumagalli F.; Staszewsky L.; Ristagno G.; Olivari D.; Masson S.; De Giorgio D.; Ceriani S.; Affatato R.; De Logu F.; Nassini R.; Milioli M.; Facchinetti F.; Cantoni S.; Trevisani M.; Letizia T.; Russo I.; Salio M.; Latini R. (2019). Monocrotaline-induced pulmonary arterial hypertension: Time-course of injury and comparative evaluation of macitentan and Y-27632, a Rho kinase inhibitor. EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 865, pp. 0-0, ISSN:0014-2999 DOI

Maura Calvani , Lorenzo Cavallini, Annalisa Tondo , Valentina Spinelli , Luisa Ricci , Amada Pasha , Gennaro Bruno , Daniela Buonvicino , Elisabetta Bigagli , Marina Vignoli , Francesca Bianchini , Laura Sartiani , Maura Lodovici , Roberto Semeraro, Filippo Fontani , Francesco De Logu , Massimo Dal Monte , Paola Chiarugi, Claudio Favre , and Luca Filippi (2018). "β3-Adrenoreceptors Control Mitochondrial Dormancy in Melanoma and Embryonic Stem Cells,. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, pp. 1-10, ISSN:1942-0900

Marone, IM; De Logu F; Nassini R; De Carvalho Goncalves M, Benemei S, Ferreira J, Piyush J; Li Puma S, Bunnett NW, Geppetti P; Materazzi s (2018). TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice. BRAIN, vol. 141, pp. 2312-2328, ISSN:0006-8950 DOI

Boccella, Serena; Guida, Francesca; De Logu, Francesco; De Gregorio, Danilo; Mazzitelli, Mariacristina; Belardo, Carmela; Iannotta, Monica; Serra, Nicola; Nassini, Romina; de Novellis, Vito; Geppetti, Pierangelo; Maione, Sabatino; Luongo, Livio (2018). Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain. THE FASEB JOURNAL, pp. fj201801033R-fj201801033R, ISSN:0892-6638 DOI

Antoniazzi, Caren Tatiane De David; Nassini, Romina; Rigo, Flávia Karine; Milioli, Alessandra Marcon; Bellinaso, Fernando; Camponogara, Camila; Silva, Cássia Regina; de Almeida, Amanda Spring; Rossato, Mateus Fortes; De Logu, Francesco; Oliveira, Sara Marchesan; Cunha, Thiago Mattar; Geppetti, Pierangelo; Ferreira, Juliano; Trevisan, Gabriela (2018). Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain. INTERNATIONAL JOURNAL OF CANCER, pp. 0-., ISSN:0020-7136 DOI

de David Antoniazzi C.T.; De Pra S.D.-T.; Ferro P.R.; Silva M.A.; Adamante G.; de Almeida A.S.; Camponogara C.; da Silva C.R.; de Bem Silveira G.; Silveira P.C.L.; Oliveira S.M.; Rigo F.K.; De Logu F.; Nassini R.; Trevisan G. (2018). Topical treatment with a transient receptor potential ankyrin 1 (TRPA1) antagonist reduced nociception and inflammation in a thermal lesion model in rats. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 125, pp. 28-38, ISSN:0928-0987 DOI Accesso ONLINE all'editore

Tonello R, FusiC, Materazzi S, Marone IM, De Logu F, Benemei S, Gonçalves M, Coppi E, Castro-Junior CJ, Gomez MV, Geppetti P, Ferreira J, Nassini R. (2017). The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice. BRITISH JOURNAL OF PHARMACOLOGY, pp. 0-0, ISSN:0007-1188 DOI

Mandalà M, De Logu F, Merelli B, Nassini R, Massi D. (2017). Immunomodulating property of MAPK inhibitors: From translational knowledge to clinical implementation. LABORATORY INVESTIGATION, vol. 97, pp. 166-175, ISSN:0023-6837 DOI Accesso ONLINE all'editore

Massi D; Romano E, Rulli E, Merelli B; Nassini R, De Logu F, Bieche I, Baroni G; Cattaneo L, Xue G, Mandalà M. (2017). Baseline β-catenin, programmed death-ligand 1 expression and tumour-infiltrating lymphocytes predict response and poor prognosis in BRAF inhibitor-treated melanoma patients. EUROPEAN JOURNAL OF CANCER, vol. 78, pp. 70-81, ISSN:0959-8049 DOI Accesso ONLINE all'editore

Benemei S; De Logu F; Li Puma S; Marone IM; Coppi E; Ugolin F; Liedtke W; Pollastro F; Appendino G; Geppetti P; Materazzi S; Nassini R. (2017). The anti-migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel. BRITISH JOURNAL OF PHARMACOLOGY, vol. 174, pp. 2897-2911, ISSN:0007-1188 DOI Accesso ONLINE all'editore

De Logu F, Nassini R, Materazzi S, Carvalho Gonçalves M, Nosi D, Rossi Degl'Innocenti D, Marone IM, Ferreira J, Li Puma S, Benemei S, Trevisan G, Souza Monteiro De Araújo D, Patacchini R, Bunnett NW, Geppetti, P. (2017). Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice. NATURE COMMUNICATIONS, vol. 8, pp. 1887-1887, ISSN:2041-1723 DOI Accesso ONLINE all'editore

Parenti, A; De Logu, F; Geppetti, P; Benemei, S1. (2016). What does evidence indicate about the role of TRP channels in inflammatory and immune cells?. BRITISH JOURNAL OF PHARMACOLOGY, vol. 173, pp. 953-969, ISSN:1476-5381 DOI

De Logu F, Tonello R, Materazzi S, Nassini R, Fusi C, Coppi E, Li Puma S, Marone IM, Sadofsky LR, Morice AM, Susini T, Terreni A, Moneti G, Di Tommaso M, Geppetti P, Benemei S. (2016). TRPA1 mediates aromatase inhibitor-evoked pain by the aromatase substrate androstenedione. CANCER RESEARCH, vol. 76, pp. 7024-7035, ISSN:0008-5472 DOI Accesso ONLINE all'editore

De Logu, Francesco; Patacchini, Riccardo; Fontana, Giovanni; Geppetti, Pierangelo (2016). TRP functions in the broncho-pulmonary system. SEMINARS IN IMMUNOPATHOLOGY, vol. 38, pp. 321-329, ISSN:1863-2297 DOI Accesso ONLINE all'editore

Trevisan G, Benemei S, Materazzi S, De Logu F, De Siena G, Fusi C, Fortes Rossato M, Coppi E, Marone IM, Ferreira J, Geppetti P, Nassini R. (2016). TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress. BRAIN, vol. 139, pp. 1361-1377, ISSN:0006-8950 DOI Accesso ONLINE all'editore

Falanga A, Marchetti M, Massi D, Merelli B, Verzeroli C, Russo L, Rulli E, Tondini C, Legramandi L, Nassini R, Scatena C, De Logu F, Cattaneo L, Mandalà M. (2016). Thrombophilic status may predict prognosis in patients with metastatic BRAFV600-mutated melanoma who are receiving BRAF inhibitors.. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, vol. 74(6):, pp. 1254-1256, ISSN:0190-9622 DOI

Prandini P, De Logu F, Fusi C, Provezza L, Nassini R, Montagner G, Materazzi S, Munari S, Gilioli E, Bezzerri V, Finotti A, Lampronti I, Tamanini A, Dechecchi MC, Lippi G, Ribeiro CM, Rimessi A, Pinton P, Gambari, R, Geppetti P, Cabrini G. (2016). Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, vol. 55, pp. 645-656-656, ISSN:1044-1549 DOI

Nassini R, Fusi C, Materazzi S, Coppi E, Tuccinardi T, Marone IM, De Logu F, Preti D, Tonello R, Chiarugi A, Patacchini R, Geppetti P, Benemei S. (2015). The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives. BRITISH JOURNAL OF PHARMACOLOGY, vol. 172, pp. 3397-3411, ISSN:1476-5381 DOI Accesso ONLINE all'editore

Fusi C, Benemei S, Coppi E, Trevisan Dos Santos G, Marone IM, Minocci D, De Logu F, Di Tommaso M, Susini T, Moneti G, Pieraccini G, Geppetti P, Materazzi S, Nassini R. (2014). Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1. NATURE COMMUNICATIONS, vol. 5, pp. 5736-5749, ISSN:2041-1723 DOI Accesso ONLINE all'editore

Francesco DE LOGU

Curriculum

Education and Training

2013 Degree in Biological Science, University of Florence

2013-2015 Research Fellowship in Pharmacology, University of Florence, Department of Health Sciences, Clinical Pharmacology and Oncology Unit

2015-2018 PhD in Clinical Sciences-Pain Therapy, University of Florence, Department of Health Sciences, Clinical Pharmacology and Oncology Unit

2019 FELASA educational Course Care and use of laboratory animals: mice, rats and zebrafishat University of Crete Modules (A, B, C, D -1, 2, 3.1, 4, 5, 6.1)

2019 Teaching course on ‘Application of immunohistochemistry in pharmacology’ Universidade Federal de Santa Maria-Department of Physiology and Pharmacology, Santa Maria, Brazil.

2019 Assistant Professor (grade A), University of Florence, Department of Health Sciences Clinical Pharmacology and Oncology Unit.

Prizes and awards

2016 Best oral presentation at the 37th Congresso Nazionale della Società Italiana di Farmacologia, Napoli, Italy, 27-30 October 2015

2018 Italian National Prize “SIF-Farmindustria” Edtion 2018, for the best pharmacological research

2019 Research Prize “Fondazione Valentina de Castro” for the best publication

2019 Italian Prix Galien, “Premio per la ricerca, l’innovazione dei farmaci e dei dispositivi medici” for the best publication.

2019 Best oral presentation at the 33° Congresso Nazionale della Società Italiana per lo Studio delle Cefalee, Napoli, Italy, 14-16 June 2019.

Congresses speaker

2016 37^th Congresso Nazionale della Società Italiana di Farmacologia, Napoli,Italy, 27-30 October 2015

2018 Monothematic Congress SIF, Glial Cells and Therapeutic Perspective: Form Maladaptive Plasticity to Neurorestoration. Firenze, 29 June 2018.

2019 33° Congresso Nazionale della Società Italiana per lo Studio delle Cefalee, Napoli, Italy, 14-16 June 2019.

2019 50th anniversary of the foundation of the EORTC Melanoma Group

Function in the international Scientific Community

2017-today Responsible for the Illustration Redraw Service for Virchows Archiv

2019 Review Editor in Experimental Pharmacology and Drug Discovery for Frontiers in Pharmacology

2020 Operational Coordinator of the Advanced Bioimaging Research Unit (ABiR)

2020 Scientific Evaluator for the Czech Academy of Sciences

Scientific society member

Società Italiana di Farmacologia (SIF), International Association for the Study of Pain (IASP), Società Italiana per lo Studio delle Cefalee (SISC)

Research experience

Francesco De Logu is a basic scientist who has opened a new area of investigation in the lab by coupling pharmacology and bio-imaging. Francesco, using unique expertise in several in vitro (molecular and cellular biology and immunohistochemistry) and in vivo (mastering complex models of diseases in mice) techniques, has markedly contributed to the understanding of the cellular and molecular basis of neuroinflammatory pathways that sustain chronic pain. Editor in Experimental Pharmacology and Drug Discovery, Frontiers in Pharmacology.

Francesco De Logu is author of 32 peer-reviewed articles. He participated to 15 national and international congresses.

Scientific records

Total Citations = 349; H-Index 11 (Scopus Basic Search)